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Coexpression cluster:C480

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Full id: C480_Pericytes_Skeletal_skeletal_mesenchymal_Hepatic_diaphragm_tongue



Phase1 CAGE Peaks

Hg19::chr11:67186174..67186179,+p@chr11:67186174..67186179
+
Hg19::chr11:67186200..67186211,+p@chr11:67186200..67186211
+
Hg19::chr13:75493774..75493776,-p@chr13:75493774..75493776
-
Hg19::chr18:8054314..8054316,-p@chr18:8054314..8054316
-
Hg19::chr19:48281847..48281853,+p7@SEPW1
Hg19::chr19:48283739..48283754,+p@chr19:48283739..48283754
+
Hg19::chr1:203052309..203052311,-p@chr1:203052309..203052311
-
Hg19::chr1:203055129..203055147,-p1@MYOG
Hg19::chr1:203144944..203144961,-p1@MYBPH
Hg19::chr1:32138785..32138796,-p18@COL16A1
Hg19::chr1:32138798..32138820,-p13@COL16A1
Hg19::chr22:24026194..24026197,-p5@GUSBP11
Hg19::chr2:121637394..121637397,+p@chr2:121637394..121637397
+
Hg19::chr2:218718071..218718103,-p@chr2:218718071..218718103
-
Hg19::chr4:167520111..167520112,-p@chr4:167520111..167520112
-
Hg19::chr8:144874971..144874988,-p@chr8:144874971..144874988
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Hg19::chr8:144875208..144875222,-p@chr8:144875208..144875222
-
Hg19::chr8:144875233..144875250,-p@chr8:144875233..144875250
-
Hg19::chr8:144875310..144875315,-p19@SCRIB
Hg19::chr9:136390071..136390087,-p1@TMEM8C


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0005597collagen type XVI0.0169257035205463
GO:0005593FACIT collagen0.0380648999849687
GO:0006942regulation of striated muscle contraction0.0380648999849687
GO:0030934anchoring collagen0.0380648999849687
GO:0032982myosin filament0.044193204806296
GO:0005863striated muscle thick filament0.044193204806296
GO:0005859muscle myosin complex0.044193204806296
GO:0016460myosin II complex0.044193204806296
GO:0006941striated muscle contraction0.044193204806296
GO:0006937regulation of muscle contraction0.044193204806296
GO:0005178integrin binding0.044193204806296
GO:0048741skeletal muscle fiber development0.044193204806296
GO:0048747muscle fiber development0.044193204806296
GO:0008307structural constituent of muscle0.044193204806296
GO:0030017sarcomere0.044193204806296
GO:0008430selenium binding0.044193204806296
GO:0022610biological adhesion0.044193204806296
GO:0007155cell adhesion0.044193204806296
GO:0030016myofibril0.044193204806296
GO:0005581collagen0.044193204806296
GO:0044424intracellular part0.044193204806296
GO:0044449contractile fiber part0.0451849650734512
GO:0043292contractile fiber0.0451849650734512
GO:0005737cytoplasm0.0451849650734512
GO:0007519skeletal muscle development0.0451849650734512



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
cell of skeletal muscle6.74e-089
Uber Anatomy
Ontology termp-valuen
adult organism4.83e-14115
organism subdivision3.31e-09365
brain1.29e-0769
future brain1.29e-0769
central nervous system1.81e-0782
neural tube6.41e-0757
neural rod6.41e-0757
future spinal cord6.41e-0757
neural keel6.41e-0757
regional part of nervous system7.53e-0794
nervous system7.53e-0794
regional part of brain9.46e-0759
anterior region of body9.65e-07129
craniocervical region9.65e-07129


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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