UBERON:0002106
From FANTOM5_SSTAR
Name: | spleen | ||
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Definition: | "Organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system.[1] In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve in case of hemorrhagic shock, especially in animals like horses (not in humans), while recycling iron.[2] It synthesizes antibodies in its white pulp and removes, from blood and lymph node circulation, antibody-coated bacteria along with antibody-coated blood cells." [Wikipedia:Spleen] | ||
Xrefs: |
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Comments: | This class was created automatically from a combination of ontologies | ||
Alt_id: | UBERON:FMA_7196-MA_0000141-MIAA_0000085-XAO_0000328-ZFA_0000436 | ||
Subset: |
organ_slim uberon_slim vertebrate_core |
Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data
Parents
is_a: | UBERON:0000077(mixed endoderm/mesoderm-derived structure),UBERON:0002075(viscus),UBERON:0004177(hemopoietic organ),UBERON:0005057(immune organ),UBERON:0005172(abdomen element) |
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develops_from: | UBERON:0003104(mesenchyme),UBERON:0006293(spleen primordium) |
part_of: | UBERON:0000916(abdomen),UBERON:0001007(digestive system),UBERON:0002323(body cavity),UBERON:0002390(hematopoietic system),UBERON:0002405(immune system) |
Children
is a: | FF:10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL) |
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derives from: | FF:0010025 (human spleen - adult sample),FF:0010044 (human spleen - fetal sample),FF:0011306 (mouse spleen- adult sample),FF:0011360 (mouse spleen- embryo E16 sample),FF:0011417 (mouse spleen- neonate N10 sample),FF:0011430 (mouse spleen- neonate N20 sample),FF:0011491 (mouse spleen- neonate N25 sample),FF:0011517 (mouse spleen-, embryo E18 sample) |
Ontology Tree: Loaded from BioPortal
Ontorolgy tree(Small window open)
FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology
Human (Homo sapiens)
- 10025-101D7 (spleen, adult, pool1)
- 10044-101F8 (spleen, fetal, pool1)
- 10095-102C5
- 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
- 1271-21F2 (spleen, embryo E18)
- 1354-25G3 (spleen, neonate N25)
- 25-2G2 (spleen, adult)
- 461-43C1 (spleen, embryo E16)
- 752-24D1 (spleen, neonate N10)
- 824-19H1 (spleen, neonate N20)
Mouse (Mus musculus)
- 10025-101D7 (spleen, adult, pool1)
- 10044-101F8 (spleen, fetal, pool1)
- 10095-102C5
- 10424-106D1 (splenic lymphoma with villous lymphocytes cell line:SLVL)
- 1271-21F2 (spleen, embryo E18)
- 1354-25G3 (spleen, neonate N25)
- 25-2G2 (spleen, adult)
- 461-43C1 (spleen, embryo E16)
- 752-24D1 (spleen, neonate N10)
- 824-19H1 (spleen, neonate N20)
Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0002106 (spleen), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data