MCL coexpression mm9:339

Phase1 CAGE Peaks

	Short description
Mm9::chr10:77512581..77512592,+	p3@Dnmt3l
Mm9::chr10:77512605..77512612,+	p7@Dnmt3l
Mm9::chr12:3871355..3871364,+	p@chr12:3871355..3871364 +
Mm9::chr13:47139250..47139274,+	p@chr13:47139250..47139274 +
Mm9::chr15:13062678..13062684,-	p@chr15:13062678..13062684 -
Mm9::chr15:97929103..97929108,-	p@chr15:97929103..97929108 -
Mm9::chr16:48431443..48431452,+	p2@Morc1
Mm9::chr19:46745201..46745211,-	p@chr19:46745201..46745211 -
Mm9::chr2:169058730..169058732,-	p@chr2:169058730..169058732 -
Mm9::chr3:136950856..136950861,+	p@chr3:136950856..136950861 +
Mm9::chr4:129606011..129606014,+	p@chr4:129606011..129606014 +
Mm9::chr4:129606033..129606044,+	p@chr4:129606033..129606044 +
Mm9::chr7:12573893..12573904,-	p@chr7:12573893..12573904 -
Mm9::chr7:12573906..12573931,-	p@chr7:12573906..12573931 -
Mm9::chr7:50683014..50683022,+	p4@Lim2
Mm9::chr7:50683034..50683049,+	p3@Lim2
Mm9::chr8:73125228..73125269,-	p@chr8:73125228..73125269 -
Mm9::chr8:74241107..74241116,-	p@chr8:74241107..74241116 -
Mm9::chr9:14545062..14545068,-	p7@Piwil4
Mm9::chr9:14545086..14545097,-	p4@Piwil4
Mm9::chr9:14545110..14545121,-	p1@Piwil4
Mm9::chr9:14545135..14545140,-	p6@Piwil4
Mm9::chr9:55139944..55139951,-	p@chr9:55139944..55139951 -

Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

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GO ID	GO name	FDR corrected p-value
GO:0007275	multicellular organismal development	0.021161115316747
GO:0032502	developmental process	0.021161115316747
GO:0021937	Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	0.021161115316747
GO:0021692	cerebellar Purkinje cell layer morphogenesis	0.021161115316747
GO:0021940	positive regulation of granule cell precursor proliferation	0.021161115316747
GO:0021694	cerebellar Purkinje cell layer formation	0.021161115316747
GO:0021936	regulation of granule cell precursor proliferation	0.021161115316747
GO:0021702	cerebellar Purkinje cell differentiation	0.021161115316747
GO:0021534	cell proliferation in hindbrain	0.021161115316747
GO:0021930	granule cell precursor proliferation	0.021161115316747
GO:0021924	cell proliferation in the external granule layer	0.021161115316747
GO:0032501	multicellular organismal process	0.021161115316747
GO:0021697	cerebellar cortex formation	0.021161115316747
GO:0021533	cell differentiation in hindbrain	0.021161115316747
GO:0021680	cerebellar Purkinje cell layer development	0.0233375147164997
GO:0021696	cerebellar cortex morphogenesis	0.0235599773010943
GO:0021587	cerebellum morphogenesis	0.0237560075770642
GO:0021575	hindbrain morphogenesis	0.0239300109561331
GO:0008270	zinc ion binding	0.0242251532587318
GO:0021695	cerebellar cortex development	0.0242251532587318
GO:0005720	nuclear heterochromatin	0.0269057763554648
GO:0022037	metencephalon development	0.0269057763554648
GO:0021549	cerebellum development	0.0269057763554648
GO:0000794	condensed nuclear chromosome	0.0313771730989331
GO:0000790	nuclear chromatin	0.0332211727732593
GO:0046914	transition metal ion binding	0.0332211727732593
GO:0000792	heterochromatin	0.0358360502863889
GO:0030902	hindbrain development	0.0402956744087905
GO:0000793	condensed chromosome	0.0407521414766671

Relative expression of the co-expression cluster over median <br>Analyst:

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Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

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Uber Anatomy

Ontology term	p-value	n
testis	1.21e-49	14
male reproductive organ	2.35e-46	15
male organism	1.78e-43	16
male reproductive system	1.78e-43	16
external genitalia	6.20e-41	17
indifferent external genitalia	6.20e-41	17
indifferent gonad	6.20e-41	17
gonad	1.13e-38	18
gonad primordium	1.13e-38	18
reproductive organ	4.66e-29	24
reproductive structure	7.77e-27	26
reproductive system	7.77e-27	26
body cavity	6.84e-19	37
body cavity or lining	6.84e-19	37
body cavity precursor	2.14e-18	38
anatomical cavity	6.32e-18	39
anatomical space	2.88e-12	57
immaterial anatomical entity	7.96e-09	79

TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

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Novel motifs

JASPAR motifs

Motifs	-log10(p-value)
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