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UBERON:0000007

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Name:pituitary gland
Definition:"The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]." [Wikipedia:Pituitary_gland, ZFIN:curator]
Xrefs:
links:

AAO:0010536
BM:Die-Hy-HY
BTO:0001073
EFO:0000857
EHDAA:2183
EHDAA:4477
EHDAA2:0001471
EMAPA:16647
EMAPA:16898
EV:0100132
FMA:13889
GAID:457
[ 200px-Gray1180.png 200px-Gray1180.png]
MA:0000176
MAT:0000077
MESH:A.06.407.747
MIAA:0000077
ncithesaurus:Pituitary_Gland
NIF_GrossAnatomy:birnlex_1353
OpenCyc:Mx4rv6NQYJwpEbGdrcN5Y29ycA
SCTID:181125003
TAO:0000118
VHOG:0000143
XAO:0000017

ZFA:0000118
Synonyms: "glandula pituitaria" RELATED [BTO:0001073]
"hypophysis" RELATED [ZFA:0000118]
"hypophysis cerebri" RELATED [MA:0000176]
"pituitary" EXACT [BTO:0001073]
"pituitary body" EXACT [BTO:0001073]
Comments:Taxon notes: The lamprey possesses a distinct pituitary organ and hormones, the ascidian does not show distinct evidence of them [Sower S, Freamat M, Kavanaugh S. The origins of the vertebrate hypothalamic窶菟ituitary窶堵onadal (HPG) and hypothalamic窶菟ituitary窶鍍hyroid (HPT) endocrine systems: new insights from lampreys. Gen Comp Endocrinol 2009;161:20-9]
Subset: organ_slim
uberon_slim
vertebrate_core

Ontology association<br>Each term has an is_a parent in the Uberon Ontology, which has a linkage to an another entity and FANTOM5 samples.Libraries were grouped into mutually exclusive facets according to the FANTOM5 sample ontology mapping to UBERON ontologies.<br><br>link to ontology dataset<br>data


Parents

is_a:UBERON:0002368(endocrine gland),UBERON:0003296(gland of diencephalon),UBERON:0010133(neuroendocrine gland)
develops_from:UBERON:0000924(ectoderm)
part_of:UBERON:0001894(diencephalon)



Children

derives from:FF:0010162 (human pituitary gland - adult sample),FF:0011303 (mouse pituitary gland- adult sample),FF:0011317 (mouse pituitary gland- embryo E12 sample),FF:0011325 (mouse pituitary gland- embryo E13 sample),FF:0011334 (mouse pituitary gland- embryo E14 sample),FF:0011345 (mouse pituitary gland- embryo E15 sample),FF:0011353 (mouse pituitary gland- embryo E16 sample),FF:0011507 (mouse pituitary gland- neonate N00 sample),FF:0011519 (mouse pituitary gland- embryo E17 sample)
part of:FF:0000114 (mouse pituitary cell),UBERON:0002196 (adenohypophysis)

Ontology Tree: Loaded from BioPortal

Ontorolgy tree(Small window open)

FF samples<br>It includes FANTOM5 samples that overlay the Uberon ontology


Human (Homo sapiens)

... further results Mouse (Mus musculus)

... further results


Enrichment analysis: top 100 FFCP enriched with this ontology term TOP 100 FANTOM5 Cage Peaks enriched with UBERON:0000007 (pituitary gland), sorted by p-values <br>Analyst: Hideya Kawaji<br><br>link to source dataset <br>human : data <br>mouse : data