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MCL coexpression mm9:833

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Phase1 CAGE Peaks

 Short description
Mm9::chr16:85080106..85080121,-p@chr16:85080106..85080121
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Mm9::chr16:85080128..85080143,-p@chr16:85080128..85080143
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Mm9::chr16:85080172..85080187,-p@chr16:85080172..85080187
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Mm9::chr16:85120817..85120847,-p@chr16:85120817..85120847
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Mm9::chr2:121129145..121129157,+p@chr2:121129145..121129157
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Mm9::chr4:149022062..149022065,+p@chr4:149022062..149022065
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Mm9::chr5:136387216..136387230,-p@chr5:136387216..136387230
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Mm9::chr7:17501688..17501702,-p@chr7:17501688..17501702
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Mm9::chr9:109906142..109906146,+p@chr9:109906142..109906146
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006874cellular calcium ion homeostasis0.00273189028276919
GO:0055074calcium ion homeostasis0.00273189028276919
GO:0006875cellular metal ion homeostasis0.00273189028276919
GO:0055065metal ion homeostasis0.00273189028276919
GO:0030005cellular di-, tri-valent inorganic cation homeostasis0.00339561591060371
GO:0055066di-, tri-valent inorganic cation homeostasis0.00339561591060371
GO:0030003cellular cation homeostasis0.00339561591060371
GO:0055080cation homeostasis0.00339561591060371
GO:0051233spindle midzone0.00421926693595706
GO:0048669collateral sprouting in the absence of injury0.00421926693595706
GO:0006873cellular ion homeostasis0.00421926693595706
GO:0055082cellular chemical homeostasis0.00421926693595706
GO:0050801ion homeostasis0.00461903084077554
GO:0007268synaptic transmission0.00461903084077554
GO:0032469endoplasmic reticulum calcium ion homeostasis0.00461903084077554
GO:0016199axon midline choice point recognition0.00461903084077554
GO:0051563smooth endoplasmic reticulum calcium ion homeostasis0.00461903084077554
GO:0051319G2 phase0.00461903084077554
GO:0000085G2 phase of mitotic cell cycle0.00461903084077554
GO:0048878chemical homeostasis0.0050343338130714
GO:0019725cellular homeostasis0.0050343338130714
GO:0019226transmission of nerve impulse0.00546315535128408
GO:0048668collateral sprouting0.00572326810172875
GO:0051124synaptic growth at neuromuscular junction0.00626799780861376
GO:0016198axon choice point recognition0.00626799780861376
GO:0016322neuron remodeling0.00626799780861376
GO:0045931positive regulation of progression through mitotic cell cycle0.00626799780861376
GO:0035235ionotropic glutamate receptor signaling pathway0.00626799780861376
GO:0042592homeostatic process0.00833950846167801
GO:0007267cell-cell signaling0.00833950846167801
GO:0001967suckling behavior0.00990585192898534
GO:0006378mRNA polyadenylation0.0106342712872807
GO:0006878cellular copper ion homeostasis0.0106342712872807
GO:0035253ciliary rootlet0.0106696132004251
GO:0055070copper ion homeostasis0.0106696132004251
GO:0007617mating behavior0.0106696132004251
GO:0042551neuron maturation0.0106696132004251
GO:0007215glutamate signaling pathway0.0112465543043183
GO:0008088axon cargo transport0.0112465543043183
GO:0043631RNA polyadenylation0.0120612685275445
GO:0045787positive regulation of progression through cell cycle0.0125305013899836
GO:0008038neuron recognition0.0125305013899836
GO:0031594neuromuscular junction0.0129569674991925
GO:0007618mating0.0129569674991925
GO:0031124mRNA 3'-end processing0.0130622824706538
GO:0044441cilium part0.0130622824706538
GO:0019098reproductive behavior0.0130622824706538
GO:0031123RNA 3'-end processing0.0155283450968913
GO:0007416synaptogenesis0.0159234052610371
GO:0022610biological adhesion0.0159234052610371
GO:0007155cell adhesion0.0159234052610371
GO:0065008regulation of biological quality0.0162361224778823
GO:0007528neuromuscular junction development0.0162361224778823
GO:0007346regulation of progression through mitotic cell cycle0.0162361224778823
GO:0051705behavioral interaction between organisms0.0169178940622229
GO:0007632visual behavior0.0169178940622229
GO:0008542visual learning0.0169178940622229
GO:0050803regulation of synapse structure and activity0.0173809901844654
GO:0007049cell cycle0.0192668237931291
GO:0005905coated pit0.0225298621556466
GO:0043169cation binding0.0225298621556466
GO:0050885neuromuscular process controlling balance0.0225298621556466
GO:0005509calcium ion binding0.0225298621556466
GO:0007631feeding behavior0.0232708228893785
GO:0048471perinuclear region of cytoplasm0.0235854233527861
GO:0005819spindle0.0252148981851856
GO:0016358dendrite development0.0254908050191597
GO:0046872metal ion binding0.025646726470486
GO:0051325interphase0.025646726470486
GO:0051329interphase of mitotic cell cycle0.025646726470486
GO:0008344adult locomotory behavior0.0259008044232371
GO:0043167ion binding0.0260312870700015
GO:0050808synapse organization and biogenesis0.0260312870700015
GO:0008037cell recognition0.0260312870700015
GO:0050905neuromuscular process0.0274308861076562
GO:0048589developmental growth0.0276443939001637
GO:0007612learning0.0278522937473146
GO:0007219Notch signaling pathway0.0280548013426924
GO:0040014regulation of multicellular organism growth0.0286456814313374
GO:0007154cell communication0.0286456814313374
GO:0005507copper ion binding0.0291705937692192
GO:0030198extracellular matrix organization and biogenesis0.0304106761431405
GO:0008201heparin binding0.0310950567036684
GO:0030534adult behavior0.0313892328921681
GO:0035264multicellular organism growth0.0313892328921681
GO:0030424axon0.0315311064098134
GO:0048741skeletal muscle fiber development0.0318050168723877
GO:0048747muscle fiber development0.0318050168723877
GO:0005929cilium0.0326716115387583
GO:0007611learning and/or memory0.0326716115387583
GO:0044463cell projection part0.0326716115387583
GO:0009416response to light stimulus0.0344083582451081
GO:0005539glycosaminoglycan binding0.0344083582451081
GO:0048469cell maturation0.0344083582451081
GO:0045177apical part of cell0.0354205845017605
GO:0007411axon guidance0.035958105758459
GO:0030247polysaccharide binding0.0364843466577046
GO:0007018microtubule-based movement0.03699965253807
GO:0007156homophilic cell adhesion0.0370651609049179
GO:0001871pattern binding0.0371293112372035
GO:0021700developmental maturation0.0393436810109145
GO:0009314response to radiation0.0398098077097394
GO:0007519skeletal muscle development0.0402666976046528
GO:0030705cytoskeleton-dependent intracellular transport0.041132097842153
GO:0043062extracellular structure organization and biogenesis0.0411538226977741
GO:0030900forebrain development0.0411750925299826
GO:0004867serine-type endopeptidase inhibitor activity0.0411959200989067
GO:0005515protein binding0.0435749539184473
GO:0045211postsynaptic membrane0.043624040836567
GO:0043005neuron projection0.0459858578633989
GO:0044456synapse part0.0474851397193773
GO:0014706striated muscle development0.0474851397193773



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
nervous system8.60e-3275
central nervous system2.20e-3173
ectoderm-derived structure2.02e-2695
ectoderm2.02e-2695
presumptive ectoderm2.02e-2695
regional part of nervous system2.16e-2554
neural tube6.88e-2452
neural rod6.88e-2452
future spinal cord6.88e-2452
neural keel6.88e-2452
neurectoderm2.94e-2264
neural plate2.94e-2264
presumptive neural plate2.94e-2264
brain3.26e-2047
future brain3.26e-2047
regional part of brain7.23e-2046
ecto-epithelium1.79e-1973
gray matter8.06e-1934
structure with developmental contribution from neural crest2.39e-1892
anterior neural tube4.03e-1740
regional part of forebrain1.09e-1639
forebrain1.09e-1639
future forebrain1.09e-1639
brain grey matter1.45e-1529
regional part of telencephalon1.45e-1529
telencephalon1.45e-1529
pre-chordal neural plate3.58e-1549
cerebral cortex2.18e-1121
cerebral hemisphere2.18e-1121
pallium2.18e-1121
tube5.99e-10114
anatomical conduit7.26e-10122
regional part of cerebral cortex8.59e-1017
occipital lobe3.38e-0810
visual cortex3.38e-0810
neocortex3.38e-0810
posterior neural tube2.02e-0712
chordal neural plate2.02e-0712


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0854318
MA0004.10.394951
MA0006.10.238555
MA0007.10.38073
MA0009.10.82278
MA0014.10.119217
MA0017.10.26239
MA0019.10.642876
MA0024.10.779446
MA0025.11.05446
MA0027.12.46647
MA0028.10.24786
MA0029.10.757957
MA0030.10.764448
MA0031.10.729293
MA0038.10.534262
MA0040.10.835181
MA0041.13.26728
MA0042.11.51496
MA0043.10.918718
MA0046.10.858391
MA0048.10.0824771
MA0050.12.88159
MA0051.12.30238
MA0052.10.84317
MA0055.10.0882028
MA0056.10
MA0057.10.549903
MA0058.10.305206
MA0059.10.316585
MA0060.10.9744
MA0061.10.56663
MA0063.10
MA0066.10.523573
MA0067.11.16502
MA0068.10.266547
MA0069.10.843506
MA0070.10.833895
MA0071.10.431174
MA0072.10.825495
MA0073.11.0215
MA0074.10.488775
MA0076.10.279739
MA0077.11.88507
MA0078.11.40897
MA0081.10.338098
MA0083.10.917931
MA0084.11.49188
MA0087.10.87515
MA0088.10.18495
MA0089.10
MA0090.11.69525
MA0091.10.407455
MA0092.10.362847
MA0093.10.2553
MA0095.10
MA0098.10
MA0100.10.477594
MA0101.10.324888
MA0103.10.748482
MA0105.10.109964
MA0106.10.582805
MA0107.10.266586
MA0108.20.665343
MA0109.10
MA0111.10.980871
MA0113.11.36684
MA0114.10.561811
MA0115.10.921497
MA0116.10.238371
MA0117.10.88947
MA0119.10.868953
MA0122.10.909168
MA0124.11.11203
MA0125.11.03833
MA0130.10
MA0131.10.638414
MA0132.10
MA0133.10
MA0135.10.954884
MA0136.10.508047
MA0139.10.143341
MA0140.10.477483
MA0141.10.29014
MA0142.10.714976
MA0143.10.571221
MA0144.10.195095
MA0145.10.442138
MA0146.10.0111657
MA0147.10.205697
MA0148.10.410398
MA0149.10.330018
MA0062.20.113962
MA0035.20.482026
MA0039.20.0946163
MA0138.20.630612
MA0002.23.48375
MA0137.20.287486
MA0104.20.157347
MA0047.20.533516
MA0112.20.442124
MA0065.20.44341
MA0150.10.380623
MA0151.10
MA0152.10.53362
MA0153.10.971406
MA0154.10.276788
MA0155.10.0631765
MA0156.10.278949
MA0157.10.683365
MA0158.10
MA0159.10.614411
MA0160.10.413266
MA0161.10
MA0162.10.0672805
MA0163.10.542069
MA0164.10.508398
MA0080.20.267388
MA0018.20.51781
MA0099.20.624421
MA0079.20.0340753
MA0102.21.5442
MA0258.10.533988
MA0259.10.196451
MA0442.10
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