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MCL coexpression mm9:568

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Phase1 CAGE Peaks

 Short description
Mm9::chr12:111326146..111326190,-p@chr12:111326146..111326190
-
Mm9::chr13:54891345..54891350,+p@chr13:54891345..54891350
+
Mm9::chr15:43002727..43002745,-p5@Rspo2
Mm9::chr16:25865862..25865871,+p8@Trp63
Mm9::chr16:25865901..25865908,+p@chr16:25865901..25865908
+
Mm9::chr18:52718847..52718852,+p@chr18:52718847..52718852
+
Mm9::chr2:24192402..24192413,+p6@Il1rn
Mm9::chr2:24192424..24192445,+p3@Il1rn
Mm9::chr2:24192453..24192465,+p5@Il1rn
Mm9::chr2:46298201..46298233,-p1@ENSMUST00000123911
Mm9::chr3:83578591..83578595,-p@chr3:83578591..83578595
-
Mm9::chr6:117124183..117124190,+p@chr6:117124183..117124190
+
Mm9::chr8:113861783..113861814,-p2@Mlkl


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0060157urinary bladder development0.0227907741193229
GO:0007499ectoderm and mesoderm interaction0.0227907741193229
GO:0030353fibroblast growth factor receptor antagonist activity0.0256227681126851
GO:0005152interleukin-1 receptor antagonist activity0.0256227681126851
GO:0048745smooth muscle development0.0256227681126851
GO:0048019receptor antagonist activity0.0256227681126851
GO:0030547receptor inhibitor activity0.0256227681126851
GO:0030859polarized epithelial cell differentiation0.0256227681126851
GO:0001736establishment of planar polarity0.0256227681126851
GO:0007164establishment of tissue polarity0.0256227681126851
GO:0002347response to tumor cell0.0256227681126851
GO:0030545receptor regulator activity0.0256227681126851
GO:0007267cell-cell signaling0.0256227681126851
GO:0010464regulation of mesenchymal cell proliferation0.0256227681126851
GO:0002053positive regulation of mesenchymal cell proliferation0.0256227681126851
GO:0010463mesenchymal cell proliferation0.0256227681126851
GO:0001738morphogenesis of a polarized epithelium0.0294697120049581
GO:0005149interleukin-1 receptor binding0.0303602380595734
GO:0030308negative regulation of cell growth0.031156630686983
GO:0031069hair follicle morphogenesis0.0318730099422934
GO:0045792negative regulation of cell size0.039307685169038
GO:0005104fibroblast growth factor receptor binding0.039307685169038
GO:0030216keratinocyte differentiation0.0436033990801299
GO:0030073insulin secretion0.0436033990801299
GO:0045926negative regulation of growth0.0440452218976995
GO:0004672protein kinase activity0.0440452218976995
GO:0006468protein amino acid phosphorylation0.0454767631410165
GO:0030072peptide hormone secretion0.0454767631410165
GO:0002790peptide secretion0.0454767631410165
GO:0016773phosphotransferase activity, alcohol group as acceptor0.0465059855234204
GO:0016310phosphorylation0.0465059855234204
GO:0042475odontogenesis of dentine-containing teeth0.0465059855234204
GO:0030855epithelial cell differentiation0.0465059855234204
GO:0042476odontogenesis0.0465059855234204
GO:0015833peptide transport0.0465059855234204
GO:0022404molting cycle process0.0465059855234204
GO:0001942hair follicle development0.0465059855234204
GO:0022405hair cycle process0.0465059855234204
GO:0007166cell surface receptor linked signal transduction0.0465059855234204
GO:0046879hormone secretion0.0465059855234204
GO:0042633hair cycle0.0465059855234204
GO:0042303molting cycle0.0465059855234204
GO:0006793phosphorus metabolic process0.0482960797623162
GO:0006796phosphate metabolic process0.0482960797623162
GO:0007498mesoderm development0.0482960797623162
GO:0048730epidermis morphogenesis0.0482960797623162
GO:0007219Notch signaling pathway0.0482960797623162



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
smooth muscle cell8.11e-123
vascular associated smooth muscle cell8.11e-123
aortic smooth muscle cell8.11e-123
smooth muscle myoblast8.11e-123


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.00104704
MA0004.10.279808
MA0006.10.14766
MA0007.10.267314
MA0009.10.678286
MA0014.10.0830612
MA0017.10.166909
MA0019.10.506787
MA0024.10.636635
MA0025.10.9035
MA0027.12.3071
MA0028.10.470606
MA0029.10.616052
MA0030.10.622264
MA0031.11.43735
MA0038.10.405578
MA0040.10.690239
MA0041.10.218039
MA0042.10.207696
MA0043.10.771094
MA0046.10.712646
MA0048.10.0358824
MA0050.10.840337
MA0051.11.06334
MA0052.10.697946
MA0055.10.0835619
MA0056.10
MA0057.10.302463
MA0058.10.202403
MA0059.10.212009
MA0060.10.0941959
MA0061.11.20639
MA0063.10
MA0066.10.395746
MA0067.11.01206
MA0068.10.571204
MA0069.10.698271
MA0070.10.688999
MA0071.10.838726
MA0072.10.680902
MA0073.10.000800861
MA0074.10.363923
MA0076.10.181159
MA0077.10.660245
MA0078.10.443468
MA0081.10.230351
MA0083.11.8156
MA0084.11.33532
MA0087.10.728855
MA0088.10.204026
MA0089.10
MA0090.10.251458
MA0091.10.290854
MA0092.10.70143
MA0093.10.161141
MA0095.10
MA0098.10
MA0100.10.353762
MA0101.10.219061
MA0103.10.174916
MA0105.10.196316
MA0106.11.14333
MA0107.10.508149
MA0108.22.25321
MA0109.10
MA0111.10.263095
MA0113.10.424958
MA0114.10.359761
MA0115.10.773793
MA0116.10.147513
MA0117.10.742722
MA0119.10.219527
MA0122.10.761823
MA0124.10.959967
MA0125.10.887718
MA0130.10
MA0131.10.502588
MA0132.10
MA0133.10
MA0135.10.806261
MA0136.10.38151
MA0139.10.942843
MA0140.10.353662
MA0141.10.555407
MA0142.11.40862
MA0143.12.91753
MA0144.10.365041
MA0145.10.4279
MA0146.10.11048
MA0147.10.121834
MA0148.10.293462
MA0149.10.223436
MA0062.20.0556611
MA0035.20.357786
MA0039.20.120228
MA0138.20.495254
MA0002.20.266731
MA0137.20.55008
MA0104.20.0856657
MA0047.20.404891
MA0112.21.02934
MA0065.20.429377
MA0150.10.737147
MA0151.10
MA0152.10.404987
MA0153.10.822355
MA0154.10.139881
MA0155.10.105935
MA0156.10.180505
MA0157.12.3091
MA0158.10
MA0159.10.403827
MA0160.10.80274
MA0161.10
MA0162.10.0186388
MA0163.10.0025245
MA0164.10.993886
MA0080.20.170995
MA0018.20.390455
MA0099.22.12597
MA0079.20.00289425
MA0102.21.38728
MA0258.10.336791
MA0259.10.114734
MA0442.10
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