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MCL coexpression mm9:2889

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Phase1 CAGE Peaks

 Short description
Mm9::chr14:13177759..13177769,-p@chr14:13177759..13177769
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Mm9::chr3:127336052..127336058,+p1@Neurog2
Mm9::chr3:127336115..127336130,+p4@Neurog2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0007411axon guidance0.00124906291015972
GO:0030900forebrain development0.00124906291015972
GO:0007409axonogenesis0.00124906291015972
GO:0048667neuron morphogenesis during differentiation0.00124906291015972
GO:0048812neurite morphogenesis0.00124906291015972
GO:0007420brain development0.00124906291015972
GO:0000904cellular morphogenesis during differentiation0.00124906291015972
GO:0031175neurite development0.00124906291015972
GO:0048666neuron development0.00134628048437791
GO:0007417central nervous system development0.00134628048437791
GO:0032990cell part morphogenesis0.00134628048437791
GO:0030030cell projection organization and biogenesis0.00134628048437791
GO:0048858cell projection morphogenesis0.00134628048437791
GO:0016477cell migration0.00134628048437791
GO:0030182neuron differentiation0.00134628048437791
GO:0048699generation of neurons0.00153572334330818
GO:0051674localization of cell0.00153572334330818
GO:0006928cell motility0.00153572334330818
GO:0022008neurogenesis0.00158354700218042
GO:0000902cell morphogenesis0.00265576217263822
GO:0032989cellular structure morphogenesis0.00265576217263822
GO:0007413axonal fasciculation0.00306748455208771
GO:0007399nervous system development0.00437908889444871
GO:0008038neuron recognition0.00481967251181162
GO:0048468cell development0.0124834871001263
GO:0009653anatomical structure morphogenesis0.0124834871001263
GO:0016358dendrite development0.0139131968176813
GO:0008037cell recognition0.0151342595956548
GO:0048513organ development0.0159305679619117
GO:0001764neuron migration0.0176513093251753
GO:0048731system development0.0224973360348367
GO:0048869cellular developmental process0.0224973360348367
GO:0030154cell differentiation0.0224973360348367
GO:0006355regulation of transcription, DNA-dependent0.023515171790163
GO:0006351transcription, DNA-dependent0.023515171790163
GO:0032774RNA biosynthetic process0.023515171790163
GO:0003677DNA binding0.023515171790163
GO:0045449regulation of transcription0.023515171790163
GO:0048856anatomical structure development0.023515171790163
GO:0045165cell fate commitment0.023515171790163
GO:0019219regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.023515171790163
GO:0006350transcription0.0235599839458425
GO:0010468regulation of gene expression0.0245836626103766
GO:0031323regulation of cellular metabolic process0.0260348618131743
GO:0007275multicellular organismal development0.0266433296142497
GO:0019222regulation of metabolic process0.0267785168787377
GO:0016070RNA metabolic process0.0276105812568531
GO:0016043cellular component organization and biogenesis0.0294279617847082
GO:0051179localization0.036777439749709
GO:0010467gene expression0.036777439749709
GO:0045944positive regulation of transcription from RNA polymerase II promoter0.036777439749709
GO:0007626locomotory behavior0.036777439749709
GO:0003676nucleic acid binding0.036777439749709
GO:0032502developmental process0.0384454815889651
GO:0045893positive regulation of transcription, DNA-dependent0.0404244133536262
GO:0006139nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0404244133536262
GO:0050794regulation of cellular process0.0456755795278891
GO:0045941positive regulation of transcription0.0463567189513623
GO:0045935positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process0.0465363489932472
GO:0007610behavior0.0497125321318605



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Cell Type
Ontology termp-valuen
neuron of cerebral cortex3.51e-126
CNS neuron (sensu Vertebrata)6.25e-1123
neuroblast (sensu Vertebrata)6.25e-1123

Uber Anatomy
Ontology termp-valuen
pre-chordal neural plate3.92e-1449
neurectoderm1.57e-1164
neural plate1.57e-1164
presumptive neural plate1.57e-1164
eye3.12e-109
camera-type eye3.12e-109
simple eye3.12e-109
immature eye3.12e-109
ocular region3.12e-109
visual system3.12e-109
face3.12e-109
optic cup3.12e-109
optic vesicle3.12e-109
eye primordium3.12e-109
ecto-epithelium2.56e-0973
subdivision of head4.00e-0811
ectoderm-derived structure6.86e-0895
ectoderm6.86e-0895
presumptive ectoderm6.86e-0895
regional part of forebrain8.67e-0839
forebrain8.67e-0839
future forebrain8.67e-0839
anterior neural tube1.69e-0740
sense organ2.46e-0712
sensory system2.46e-0712
entire sense organ system2.46e-0712
regional part of brain4.96e-0746
brain grey matter5.08e-0729
regional part of telencephalon5.08e-0729
telencephalon5.08e-0729
regional part of nervous system5.65e-0754
brain8.48e-0747
future brain8.48e-0747


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.899234
MA0004.10.801718
MA0006.12.49698
MA0007.10.784593
MA0009.11.27673
MA0014.10.416365
MA0017.10.635031
MA0019.11.08369
MA0024.11.23079
MA0025.11.51835
MA0027.12.9431
MA0028.10.61552
MA0029.11.20789
MA0030.11.21482
MA0031.11.17722
MA0038.10.963265
MA0040.11.28983
MA0041.11.69964
MA0042.10.69885
MA0043.11.3775
MA0046.11.31428
MA0048.10.353763
MA0050.10.845669
MA0051.10.973068
MA0052.11.29825
MA0055.10.190475
MA0056.10
MA0057.12.43475
MA0058.10.690848
MA0059.10.705317
MA0060.10.502699
MA0061.10.5406
MA0063.10
MA0066.10.951196
MA0067.11.63197
MA0068.10.343188
MA0069.11.29861
MA0070.11.28847
MA0071.10.844726
MA0072.11.2796
MA0073.10.121346
MA0074.10.911576
MA0076.10.657929
MA0077.11.2569
MA0078.11.0091
MA0081.10.732313
MA0083.11.37668
MA0084.11.96428
MA0087.11.33189
MA0088.10.27999
MA0089.10
MA0090.10.762482
MA0091.10.816659
MA0092.11.80015
MA0093.10.62555
MA0095.10
MA0098.10
MA0100.10.89873
MA0101.10.71579
MA0103.10.647985
MA0105.10.405648
MA0106.11.01755
MA0107.10.640607
MA0108.21.10817
MA0109.10
MA0111.10.778753
MA0113.10.986839
MA0114.10.537669
MA0115.11.38041
MA0116.11.46662
MA0117.11.34691
MA0119.10.716476
MA0122.11.36752
MA0124.11.57762
MA0125.11.5017
MA0130.10
MA0131.11.07881
MA0132.10
MA0133.10
MA0135.11.4152
MA0136.10.933582
MA0139.10.462282
MA0140.10.898603
MA0141.10.671467
MA0142.11.16183
MA0143.11.00467
MA0144.10.541532
MA0145.12.21145
MA0146.10.900029
MA0147.10.556853
MA0148.10.820161
MA0149.10.722227
MA0062.20.412742
MA0035.20.903829
MA0039.20.71803
MA0138.21.07027
MA0002.21.17677
MA0137.20.668025
MA0104.20.48458
MA0047.20.962424
MA0112.20.794478
MA0065.20.79573
MA0150.10.784464
MA0151.10
MA0152.10.962542
MA0153.11.43238
MA0154.10.35067
MA0155.10.312898
MA0156.10.656895
MA0157.11.12772
MA0158.10
MA0159.10.569393
MA0160.10.823568
MA0161.10
MA0162.10.166722
MA0163.11.48428
MA0164.10.933981
MA0080.20.64167
MA0018.20.944669
MA0099.21.06348
MA0079.26.70315
MA0102.22.01714
MA0258.10.520639
MA0259.10.543506
MA0442.10
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