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Coexpression cluster:C2099: Difference between revisions

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{{Coexpression_clusters
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|full_id=C2099_Adipocyte_Osteoblast_Mesenchymal_Endothelial_Renal_Retinal_Preadipocyte
|gostat_on_coexpression_clusters=GO:0006817!phosphate transport!0.034862043251305!114902$GO:0015698!inorganic anion transport!0.034862043251305!114902$GO:0006820!anion transport!0.034862043251305!114902
|id=C2099
|ontology_enrichment_celltype=CL:0000055!9.13e-21!180;CL:0000222!8.62e-19!119;CL:0000115!6.00e-16!35;CL:0002139!4.40e-15!24;CL:0002078!1.75e-14!44;CL:0000071!6.39e-12!18;CL:0002546!6.39e-12!18;CL:0000213!2.40e-11!57;CL:0000215!2.40e-11!57;CL:0000057!1.76e-10!75;CL:0000136!1.17e-08!15;CL:0000183!2.45e-08!59;CL:0000680!2.67e-08!57;CL:0000056!2.67e-08!57;CL:0000355!2.67e-08!57;CL:0000187!6.87e-08!54;CL:0000393!1.89e-07!60;CL:0000211!1.89e-07!60;CL:1000413!2.65e-07!9
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0004111!5.37e-21!241;UBERON:0000483!1.71e-20!309;UBERON:0000477!1.98e-20!286;UBERON:0000119!2.73e-20!312;UBERON:0000025!2.93e-19!194;UBERON:0002049!3.33e-19!79;UBERON:0007798!3.33e-19!79;UBERON:0000055!4.52e-19!69;UBERON:0004872!2.68e-18!84;UBERON:0003914!1.07e-16!118;UBERON:0001981!1.88e-16!60;UBERON:0007500!1.88e-16!60;UBERON:0004537!1.88e-16!60;UBERON:0006965!1.88e-16!60;UBERON:0000475!1.92e-15!365;UBERON:0001009!8.88e-15!113;UBERON:0004535!2.71e-14!110;UBERON:0000468!4.56e-13!659;UBERON:0000490!5.71e-13!138;UBERON:0007023!1.34e-12!115;UBERON:0001986!6.39e-12!18;UBERON:0004638!6.39e-12!18;UBERON:0004852!6.39e-12!18;UBERON:0000481!1.24e-10!347;UBERON:0006914!6.56e-10!25;UBERON:0005256!8.31e-10!143;UBERON:0002385!1.12e-09!63;UBERON:0001015!1.12e-09!63;UBERON:0000383!1.12e-09!63;UBERON:0000467!2.46e-09!625;UBERON:0001637!2.89e-09!42;UBERON:0003509!2.89e-09!42;UBERON:0004572!2.89e-09!42;UBERON:0001134!3.35e-09!61;UBERON:0002036!3.35e-09!61;UBERON:0003082!3.35e-09!61;UBERON:0000487!3.42e-09!22;UBERON:0000480!3.86e-09!626;UBERON:0003075!6.58e-09!86;UBERON:0007284!6.58e-09!86;UBERON:0000914!2.54e-08!83;UBERON:0002329!2.54e-08!83;UBERON:0003077!2.54e-08!83;UBERON:0003059!2.54e-08!83;UBERON:0007282!2.54e-08!83;UBERON:0009618!2.54e-08!83;UBERON:0007285!2.54e-08!83;UBERON:0004290!3.59e-08!70;UBERON:0002346!1.04e-07!90;UBERON:0001049!1.26e-07!57;UBERON:0005068!1.26e-07!57;UBERON:0006241!1.26e-07!57;UBERON:0007135!1.26e-07!57;UBERON:0004573!1.52e-07!33;UBERON:0004571!1.52e-07!33;UBERON:0005743!1.98e-07!86;UBERON:0002100!2.32e-07!216;UBERON:0003915!2.65e-07!9;UBERON:0004700!2.65e-07!9;UBERON:0001917!2.65e-07!9;UBERON:0002616!3.62e-07!59;UBERON:0000947!5.95e-07!21;UBERON:0010191!5.95e-07!21;UBERON:0000486!6.90e-07!82
}}

Latest revision as of 11:58, 17 September 2013


Full id: C2099_Adipocyte_Osteoblast_Mesenchymal_Endothelial_Renal_Retinal_Preadipocyte



Phase1 CAGE Peaks

Hg19::chr11:119211162..119211175,-p2@AB590791
Hg19::chr11:119211254..119211316,-p1@AB590791
Hg19::chr11:119211525..119211614,-p1@C1QTNF5
Hg19::chr11:119211627..119211642,-p4@C1QTNF5


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006817phosphate transport0.034862043251305
GO:0015698inorganic anion transport0.034862043251305
GO:0006820anion transport0.034862043251305



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
epithelium8.48e-20306
cell layer1.55e-19309
anatomical conduit4.36e-19240
vasculature1.02e-1878
vascular system1.02e-1878
vessel2.09e-1868
anatomical cluster1.03e-17373
splanchnic layer of lateral plate mesoderm2.37e-1783
tube2.45e-17192
epithelial tube open at both ends6.15e-1659
blood vessel6.15e-1659
blood vasculature6.15e-1659
vascular cord6.15e-1659
epithelial tube6.57e-15117
circulatory system6.93e-14112
cardiovascular system1.50e-13109
multi-cellular organism2.14e-13656
multi-tissue structure1.96e-12342
adult organism2.92e-12114
unilaminar epithelium8.97e-12148
blood vessel endothelium1.02e-1118
endothelium1.02e-1118
cardiovascular system endothelium1.02e-1118
structure with developmental contribution from neural crest8.37e-11132
muscle tissue2.75e-1064
musculature2.75e-1064
musculature of body2.75e-1064
epithelial vesicle7.24e-1078
skeletal muscle tissue7.67e-1062
striated muscle tissue7.67e-1062
myotome7.67e-1062
squamous epithelium1.22e-0925
anatomical system2.06e-09624
mesenchyme2.56e-09160
entire embryonic mesenchyme2.56e-09160
anatomical group3.18e-09625
artery3.96e-0942
arterial blood vessel3.96e-0942
arterial system3.96e-0942
trunk mesenchyme4.79e-09122
simple squamous epithelium6.45e-0922
dense mesenchyme tissue8.12e-0973
neural plate1.04e-0882
presumptive neural plate1.04e-0882
paraxial mesoderm1.24e-0872
presumptive paraxial mesoderm1.24e-0872
somite1.81e-0871
presomitic mesoderm1.81e-0871
presumptive segmental plate1.81e-0871
dermomyotome1.81e-0871
trunk paraxial mesoderm1.81e-0871
neurectoderm1.44e-0786
systemic artery1.54e-0733
systemic arterial system1.54e-0733
endothelial tube2.60e-079
arterial system endothelium2.60e-079
endothelium of artery2.60e-079
multilaminar epithelium2.84e-0783
neural tube3.99e-0756
neural rod3.99e-0756
future spinal cord3.99e-0756
neural keel3.99e-0756
aorta6.97e-0721
aortic system6.97e-0721
organism subdivision7.66e-07264


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.11.8989
MA0004.10.71247
MA0006.10.532262
MA0007.11.65296
MA0009.11.20602
MA0014.11.86845
MA0017.10.577281
MA0019.10.873355
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.10.25531
MA0050.10.69864
MA0051.10.820063
MA0052.11.12718
MA0055.10.396851
MA0056.10
MA0057.13.6449
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.841508
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.214613
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.10.604638
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.11.62583
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.11.98562
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.11.43218
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.912459
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.11.70272
MA0146.10.221129
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.20.483275
MA0138.22.1393
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.21.65877
MA0065.22.43626
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.649108
MA0155.11.61785
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.10.462502
MA0160.10.756582
MA0161.10
MA0162.10.309472
MA0163.10.539587
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.23.97967
MA0102.21.75932
MA0258.10.418966
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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