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{{f5samples
{{f5samples
|ancestors_in_anatomy_facet=UBERON:0000015,UBERON:0000025,UBERON:0000058,UBERON:0000061,UBERON:0000062,UBERON:0000077,UBERON:0000119,UBERON:0000465,UBERON:0000466,UBERON:0000467,UBERON:0000468,UBERON:0000475,UBERON:0000477,UBERON:0000479,UBERON:0000480,UBERON:0000481,UBERON:0000483,UBERON:0000922,UBERON:0000923,UBERON:0000925,UBERON:0000926,UBERON:0001007,UBERON:0001041,UBERON:0001048,UBERON:0001062,UBERON:0001173,UBERON:0001555,UBERON:0002050,UBERON:0002100,UBERON:0002294,UBERON:0002394,UBERON:0002423,UBERON:0002532,UBERON:0003104,UBERON:0003894,UBERON:0003914,UBERON:0003928,UBERON:0004111,UBERON:0004119,UBERON:0004120,UBERON:0004161,UBERON:0004185,UBERON:0004912,UBERON:0004921,UBERON:0005256,UBERON:0005423,UBERON:0005911,UBERON:0006235,UBERON:0007026,UBERON:0008835,UBERON:0009142
|DRA_sample_Accession=CAGE@SAMD00005118
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000063,CL:0000066,CL:0000255,CL:0000548
|accession_numbers=CAGE;DRX007833;DRR008705;DRZ000130;DRZ001515;DRZ011480;DRZ012865
|ancestors_in_disease_facet=DOID:0050687,DOID:14566,DOID:162,DOID:305,DOID:4,DOID:7
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002394,UBERON:0000058,UBERON:0001007,UBERON:0004119,UBERON:0000062,UBERON:0004111,UBERON:0000061,UBERON:0000465,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003928,UBERON:0010317,UBERON:0002294,UBERON:0001173,UBERON:0002423
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:7,DOID:305
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0101120,FF:0103910,FF:0103911
|comment=
|comment=
|created_by=
|created_by=
|creation_date=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|def=
|expression_enrichment_score=chr11:34642612..34642646,+!p1@EHF!2.37!233.75!EHF;;chr11:65686802..65686818,+!p6@DRAP1!1.65!75.13!DRAP1;;chr1:201979743..201979762,+!p1@ELF3!1.64!42.51!ELF3;;chr11:65686732..65686756,+!p2@DRAP1!1.53!134.89!DRAP1;;chr11:65667884..65667895,-!p2@FOSL1!1.52!120.78!FOSL1;;chr1:201979703..201979721,+!p2@ELF3!1.52!31.81!ELF3;;chr6:1312325..1312340,+!p1@FOXQ1!1.49!47.99!FOXQ1;;chr8:102504651..102504683,+!p1@GRHL2!1.47!28.31!GRHL2;;chr11:34642656..34642667,+!p2@EHF!1.43!25.88!EHF;;chr11:65667846..65667868,-!p1@FOSL1!1.41!627.28!FOSL1;;chr17:46682321..46682362,-!p1@HOXB6!1.41!24.89!HOXB6;;chr1:209979467..209979494,-!p1@IRF6!1.37!25.43!IRF6;;chr3:111314186..111314204,-!p1@ZBED2!1.36!22.11!ZBED2;;chr12:66218255..66218304,+!p3@HMGA2!1.33!53.92!HMGA2;;chr6:34204921..34204939,+!p3@HMGA1!1.30!557.27!HMGA1;;chr11:34645791..34645836,+!p3@EHF!1.30!19.14!EHF;;chr12:66218598..66218645,+!p2@HMGA2!1.27!80.34!HMGA2;;chr21:36421535..36421610,-!p2@RUNX1!1.26!60.12!RUNX1;;chr8:67525443..67525459,-!p2@MYBL1!1.26!25.70!MYBL1;;chr11:65668011..65668020,-!p3@FOSL1!1.26!17.16!FOSL1;;chr8:10588010..10588030,-!p1@SOX7!1.26!17.07!SOX7;;chr15:67418119..67418162,+!p5@SMAD3!1.24!18.15!SMAD3;;chr11:128457446..128457461,-!p4@ETS1!1.19!14.65!ETS1;;chr14:75988771..75988826,+!p1@BATF!1.18!18.78!BATF;;chr3:12330560..12330579,+!p1@PPARG!1.16!15.28!PPARG;;chr18:19749541..19749557,+!p1@GATA6!1.12!38.19!GATA6;;chr12:80084737..80084763,-!p3@PAWR!1.11!44.31!PAWR;;chr15:67418047..67418093,+!p4@SMAD3!1.11!15.01!SMAD3;;chr11:120107344..120107351,+!p1@POU2F3!1.10!14.11!POU2F3;;chr20:22564895..22564910,-!p1@FOXA2!1.10!11.50!FOXA2;;chr11:65686776..65686787,+!p9@DRAP1!1.09!13.30!DRAP1;;chr5:134369905..134369972,-!p1@PITX1!1.08!16.90!PITX1;;chr12:27485762..27485776,+!p3@ARNTL2!1.04!27.23!ARNTL2;;chr13:73633131..73633149,+!p1@KLF5!1.02!101.64!KLF5;;chr12:66218212..66218244,+!p5@HMGA2!1.00!13.21!HMGA2;;chr12:77459306..77459365,-!p1@E2F7!0.99!112.96!E2F7;;chr20:50159198..50159299,-!p1@NFATC2!0.99!12.94!NFATC2;;chr17:70117153..70117174,+!p1@SOX9!0.98!91.04!SOX9;;chr17:46675558..46675577,-!p2@HOXB6!0.98!8.45!HOXB6;;chr11:65554528..65554546,+!p1@OVOL1!0.96!8.09!OVOL1;;chr12:66218183..66218209,+!p4@HMGA2!0.95!15.55!HMGA2;;chr11:129245526..129245553,+!p1@BARX2!0.95!7.91!BARX2;;chr12:2986275..2986363,-!p1@FOXM1!0.94!79.26!FOXM1;;chr7:26191809..26191890,+!p1@NFE2L3!0.94!39.36!NFE2L3;;chr5:134369879..134369898,-!p2@PITX1!0.94!7.73!PITX1;;chr8:102504690..102504704,+!p3@GRHL2!0.94!7.73!GRHL2;;chr17:41277372..41277418,-!p1@BRCA1!0.92!27.59!BRCA1;;chr11:61520075..61520136,+!p1@C11orf9!0.92!16.09!C11orf9;;chr6:10415276..10415341,-!p2@TFAP2A!0.91!8.81!TFAP2A;;chr11:65554563..65554576,+!p2@OVOL1!0.91!7.10!OVOL1;;chr19:45908292..45908374,-!p1@PPP1R13L!0.90!64.08!PPP1R13L;;chr8:102504979..102505010,+!p2@GRHL2!0.90!6.92!GRHL2;;chr12:66218378..66218401,+!p6@HMGA2!0.88!10.51!HMGA2;;chr6:10413188..10413249,-!p7@TFAP2A!0.88!6.56!TFAP2A;;chr3:168864315..168864339,-!p2@MECOM!0.87!10.87!MECOM;;chr17:41623692..41623715,-!p1@ETV4!0.86!27.86!ETV4;;chr18:19749386..19749404,+!p2@GATA6!0.86!9.08!GATA6;;chr12:66218836..66218888,+!p1@HMGA2!0.85!60.75!HMGA2;;chr15:96869255..96869291,+!p6@NR2F2!0.85!11.50!NR2F2;;chr15:67418177..67418204,+!p9@SMAD3!0.85!6.02!SMAD3;;chr14:38064429..38064486,-!p1@FOXA1!0.84!5.93!FOXA1;;chr1:209979411..209979433,-!p2@IRF6!0.84!5.84!IRF6;;chr20:22565185..22565223,-!p3@FOXA2!0.83!5.75!FOXA2;;chr6:10415484..10415508,-!p3@TFAP2A!0.82!5.66!TFAP2A;;chr6:34204672..34204692,+!p1@HMGA1!0.80!644.36!HMGA1;;chr12:80084303..80084332,-!p1@PAWR!0.79!33.43!PAWR;;chr12:66218003..66218018,+!p9@HMGA2!0.79!6.47!HMGA2;;chrY:2803415..2803468,+!p1@ZFY!0.79!5.12!ZFY;;chr3:193853927..193853944,+!p1@HES1!0.78!181.53!HES1;;chr14:62162285..62162296,+!p3@HIF1A!0.78!28.67!HIF1A;;chr15:96869511..96869525,+!p16@NR2F2!0.78!5.66!NR2F2;;chrY:21906594..21906622,-!p1@KDM5D!0.78!5.03!KDM5D;;chr6:34524093..34524135,-!p1@SPDEF!0.78!5.03!SPDEF;;chr3:141087339..141087387,+!p2@ZBTB38!0.77!54.64!ZBTB38;;chr12:27485785..27485816,+!p1@ARNTL2!0.77!37.03!ARNTL2;;chr11:128392273..128392308,-!p2@ETS1!0.77!22.74!ETS1;;chr12:26277956..26277980,-!p1@BHLHE41!0.77!18.87!BHLHE41;;chr15:96874145..96874166,+!p7@NR2F2!0.77!9.98!NR2F2;;chr6:10412600..10412637,-!p1@TFAP2A!0.77!8.63!TFAP2A;;chr17:36105042..36105060,-!p1@HNF1B!0.77!4.94!HNF1B;;chr12:27485823..27485868,+!p2@ARNTL2!0.76!21.21!ARNTL2;;chr8:67525473..67525518,-!p1@MYBL1!0.76!11.50!MYBL1;;chr15:67357924..67357952,+!p2@SMAD3!0.74!33.34!SMAD3;;chr2:122042770..122042785,-!p1@TFCP2L1!0.74!4.49!TFCP2L1;;chr2:238592039..238592054,+!p4@LRRFIP1!0.74!4.49!LRRFIP1;;chr12:80084279..80084293,-!p8@PAWR!0.73!7.64!PAWR;;chr12:66218573..66218596,+!p7@HMGA2!0.73!6.74!HMGA2;;chr4:149363475..149363492,-!p2@NR3C2!0.73!4.40!NR3C2;;chr17:36105074..36105086,-!p2@HNF1B!0.73!4.31!HNF1B;;chr7:27153454..27153469,-!p2@HOXA3!0.73!4.31!HOXA3;;chr15:96874012..96874042,+!p2@NR2F2!0.72!43.23!NR2F2;;chr6:34524025..34524045,-!p3@SPDEF!0.72!4.22!SPDEF;;chr3:141087393..141087426,+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|ffid_belonging_in_development=UBERON:0001041,UBERON:0002532,UBERON:0006595,UBERON:0009497,UBERON:0010316
|fonse_cell_line=FF:0101120,FF:0103910
|fonse_cell_line=FF:0101120,FF:0103910
|fonse_cell_line_closure=FF:0101120,FF:0103910
|fonse_cell_line_closure=FF:0101120,FF:0103910
Line 35: Line 41:
|fonse_treatment_closure=
|fonse_treatment_closure=
|has_quality=
|has_quality=
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/bile%2520duct%2520carcinoma%2520cell%2520line%253aHuCCT1.CNhs10750.10432-106D9.hg19.nobarcode.bam
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/bile%2520duct%2520carcinoma%2520cell%2520line%253aHuCCT1.CNhs10750.10432-106D9.hg19.ctss.bed.gz
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/bile%2520duct%2520carcinoma%2520cell%2520line%253aHuCCT1.CNhs10750.10432-106D9.hg19.nobarcode.rdna.fa.gz
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/bile%2520duct%2520carcinoma%2520cell%2520line%253aHuCCT1.CNhs10750.10432-106D9.hg38.nobarcode.bam
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/bile%2520duct%2520carcinoma%2520cell%2520line%253aHuCCT1.CNhs10750.10432-106D9.hg38.nobarcode.ctss.bed.gz
|id=FF:10432-106D9
|id=FF:10432-106D9
|is_a=EFO:0002091;;FF:0000003;;FF:0000210;;FF:0100297;;FF:0103911
|is_a=EFO:0002091;;FF:0000210;;FF:0100297;;FF:0103911
|is_obsolete=
|library_id=CNhs10750
|library_id_phase_based=2:CNhs10750
|microRNAs=
|microRNAs_nn=
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10432
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10432
|name=bile duct carcinoma cell line:HuCCT1
|name=bile duct carcinoma cell line:HuCCT1
|namespace=FANTOM5
|namespace=FANTOM5
Line 42: Line 60:
|profile_cagescan=,,,
|profile_cagescan=,,,
|profile_hcage=CNhs10750,LSID692,release008,COMPLETED
|profile_hcage=CNhs10750,LSID692,release008,COMPLETED
|profile_rnaseq=,,,
|profile_rnaseq=
|profile_srnaseq=,,,
|profile_srnaseq=,,,
|refex=http://refex.dbcls.jp/genelist.php?lang
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|rna_box=106
|rna_box=106
|rna_catalog_number=
|rna_catalog_number=
Line 57: Line 78:
|rna_weight_ug=46.08825
|rna_weight_ug=46.08825
|sample_age=56
|sample_age=56
|sample_category=cell lines
|sample_cell_catalog=RCB1960
|sample_cell_catalog=RCB1960
|sample_cell_line=HuCCT1
|sample_cell_line=HuCCT1
Line 69: Line 91:
|sample_ethnicity=unknown
|sample_ethnicity=unknown
|sample_experimental_condition=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.95956618914634e-248!GO:0005737;cytoplasm;3.84142022629202e-199!GO:0043226;organelle;1.31141037597469e-193!GO:0043229;intracellular organelle;4.25415815306125e-193!GO:0043231;intracellular membrane-bound organelle;1.26596755219379e-186!GO:0043227;membrane-bound organelle;1.74078455706637e-186!GO:0044422;organelle part;2.06983686773336e-160!GO:0044446;intracellular organelle part;6.52241403385751e-159!GO:0044444;cytoplasmic part;8.21100049514745e-130!GO:0032991;macromolecular complex;9.65547807175113e-107!GO:0030529;ribonucleoprotein complex;6.54935136785556e-91!GO:0044237;cellular metabolic process;2.10577738241129e-84!GO:0044238;primary metabolic process;1.85763359483756e-83!GO:0005515;protein binding;3.25562053108566e-82!GO:0044428;nuclear part;3.51107434014945e-81!GO:0003723;RNA binding;2.8319475733286e-79!GO:0043170;macromolecule metabolic process;3.24284651154191e-78!GO:0005634;nucleus;1.45702740119887e-76!GO:0043233;organelle lumen;2.12967878349407e-73!GO:0031974;membrane-enclosed lumen;2.12967878349407e-73!GO:0005739;mitochondrion;1.02221808715452e-65!GO:0006412;translation;1.76488530839284e-57!GO:0005840;ribosome;4.43393893441241e-55!GO:0019538;protein metabolic process;5.56928094304972e-55!GO:0016043;cellular component organization and biogenesis;4.85627014257648e-54!GO:0043234;protein complex;6.57029118869271e-54!GO:0006396;RNA processing;2.21788551020764e-53!GO:0031090;organelle membrane;9.74232573420179e-53!GO:0044267;cellular protein metabolic process;1.49413003234075e-49!GO:0044260;cellular macromolecule metabolic process;1.08846637106691e-48!GO:0031981;nuclear lumen;6.78667056220176e-48!GO:0043228;non-membrane-bound organelle;9.11582393344743e-48!GO:0043232;intracellular non-membrane-bound organelle;9.11582393344743e-48!GO:0003735;structural constituent of ribosome;1.10448243035106e-47!GO:0015031;protein transport;3.89065968456294e-47!GO:0033036;macromolecule localization;6.10309518404829e-47!GO:0009058;biosynthetic process;4.27745384103374e-44!GO:0043283;biopolymer metabolic process;5.45948396101896e-44!GO:0009059;macromolecule biosynthetic process;1.31140456799536e-43!GO:0045184;establishment of protein localization;2.15610497714765e-42!GO:0044249;cellular biosynthetic process;2.41281917758297e-42!GO:0008104;protein localization;2.41281917758297e-42!GO:0044429;mitochondrial part;7.36556831487234e-42!GO:0031967;organelle envelope;9.38119194412488e-42!GO:0031975;envelope;2.41414773906764e-41!GO:0006996;organelle organization and biogenesis;5.09601789485374e-41!GO:0033279;ribosomal subunit;3.60097711780734e-39!GO:0016071;mRNA metabolic process;4.72531451900796e-39!GO:0006259;DNA metabolic process;1.28786710031367e-38!GO:0005829;cytosol;1.8806416940396e-38!GO:0046907;intracellular transport;1.50339162658162e-37!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.4293757394167e-37!GO:0007049;cell cycle;1.30935356373585e-36!GO:0065003;macromolecular complex assembly;1.30935356373585e-36!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.01007809391291e-36!GO:0008380;RNA splicing;2.15122240963789e-35!GO:0010467;gene expression;5.69939491521431e-35!GO:0006397;mRNA processing;1.43073616501258e-34!GO:0006886;intracellular protein transport;9.71236429970149e-33!GO:0022607;cellular component assembly;1.07928848642594e-31!GO:0000166;nucleotide binding;6.3063433794326e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.08196558757302e-28!GO:0005654;nucleoplasm;9.01709577953132e-28!GO:0022402;cell cycle process;2.76112511829764e-27!GO:0005740;mitochondrial envelope;2.37897549294483e-26!GO:0000278;mitotic cell cycle;1.17427170579555e-25!GO:0005681;spliceosome;1.95152234194874e-25!GO:0031966;mitochondrial membrane;6.41354206807522e-25!GO:0012505;endomembrane system;9.16157291656026e-25!GO:0051649;establishment of cellular localization;1.96086888987611e-24!GO:0019866;organelle inner membrane;3.93070758140238e-24!GO:0044445;cytosolic part;5.11758082939728e-24!GO:0051641;cellular localization;5.94687089207802e-24!GO:0016462;pyrophosphatase activity;1.79997259600304e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.52145907472884e-23!GO:0006974;response to DNA damage stimulus;3.07949433477111e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;3.37399015471235e-23!GO:0017111;nucleoside-triphosphatase activity;4.61239915658903e-23!GO:0044451;nucleoplasm part;6.06085976138621e-22!GO:0005743;mitochondrial inner membrane;6.09399946407331e-22!GO:0005730;nucleolus;1.46403182595416e-21!GO:0032553;ribonucleotide binding;1.60802330972493e-21!GO:0032555;purine ribonucleotide binding;1.60802330972493e-21!GO:0017076;purine nucleotide binding;2.17664569625133e-21!GO:0005694;chromosome;3.73713125095995e-21!GO:0015935;small ribosomal subunit;4.7474208864731e-21!GO:0022618;protein-RNA complex assembly;5.71975028114031e-21!GO:0016874;ligase activity;1.04877725497517e-20!GO:0000087;M phase of mitotic cell cycle;2.57507132355759e-20!GO:0006119;oxidative phosphorylation;3.09769590617765e-20!GO:0006281;DNA repair;5.49025876616483e-20!GO:0007067;mitosis;5.8289941668421e-20!GO:0022403;cell cycle phase;8.60764062032049e-20!GO:0044427;chromosomal part;1.8532928535314e-19!GO:0015934;large ribosomal subunit;3.19444262451409e-19!GO:0005524;ATP binding;8.04589644105245e-19!GO:0051301;cell division;1.93867059559086e-18!GO:0006457;protein folding;2.20150910755661e-18!GO:0031980;mitochondrial lumen;2.87248796613294e-18!GO:0005759;mitochondrial matrix;2.87248796613294e-18!GO:0032559;adenyl ribonucleotide binding;3.35189792317859e-18!GO:0003676;nucleic acid binding;4.58286744169247e-18!GO:0006260;DNA replication;5.21644092403922e-18!GO:0030554;adenyl nucleotide binding;6.4898000118865e-18!GO:0006605;protein targeting;1.72370971825102e-17!GO:0044265;cellular macromolecule catabolic process;2.38620037149396e-17!GO:0042254;ribosome biogenesis and assembly;2.82131208489762e-17!GO:0008134;transcription factor binding;3.52427285369446e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;3.76103827357567e-17!GO:0006512;ubiquitin cycle;4.04347174012691e-17!GO:0043412;biopolymer modification;5.42641186610695e-17!GO:0000279;M phase;5.57267181324724e-17!GO:0019941;modification-dependent protein catabolic process;6.23935507160037e-17!GO:0043632;modification-dependent macromolecule catabolic process;6.23935507160037e-17!GO:0044455;mitochondrial membrane part;8.18403574328432e-17!GO:0008135;translation factor activity, nucleic acid binding;9.71003888892801e-17!GO:0006511;ubiquitin-dependent protein catabolic process;1.18862042893783e-16!GO:0044257;cellular protein catabolic process;1.27823294035529e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.31193797304838e-16!GO:0043285;biopolymer catabolic process;1.93723636128544e-16!GO:0009719;response to endogenous stimulus;2.6196166221243e-16!GO:0005783;endoplasmic reticulum;3.32008946869238e-16!GO:0044432;endoplasmic reticulum part;5.99205784887943e-16!GO:0005635;nuclear envelope;1.16951736931065e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.3045691264504e-15!GO:0051276;chromosome organization and biogenesis;1.49874283057722e-15!GO:0012501;programmed cell death;1.96625614864894e-15!GO:0048770;pigment granule;2.84105348267517e-15!GO:0042470;melanosome;2.84105348267517e-15!GO:0005761;mitochondrial ribosome;3.16807570883132e-15!GO:0000313;organellar ribosome;3.16807570883132e-15!GO:0006915;apoptosis;4.07412834678872e-15!GO:0051726;regulation of cell cycle;4.0808116584385e-15!GO:0005794;Golgi apparatus;4.34552754446768e-15!GO:0031965;nuclear membrane;5.87389223800123e-15!GO:0000074;regulation of progression through cell cycle;6.03492464465308e-15!GO:0009057;macromolecule catabolic process;9.85000387952622e-15!GO:0051186;cofactor metabolic process;1.02632777777944e-14!GO:0006464;protein modification process;1.07740955155146e-14!GO:0044248;cellular catabolic process;1.60771460308649e-14!GO:0005746;mitochondrial respiratory chain;3.38167529171168e-14!GO:0030163;protein catabolic process;3.39090324121293e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.26945010504104e-14!GO:0008219;cell death;9.44391894345683e-14!GO:0016265;death;9.44391894345683e-14!GO:0006413;translational initiation;1.01877547532673e-13!GO:0016887;ATPase activity;1.03628943576023e-13!GO:0044453;nuclear membrane part;1.10977518189347e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;1.46081216134333e-13!GO:0000375;RNA splicing, via transesterification reactions;1.46081216134333e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.46081216134333e-13!GO:0003743;translation initiation factor activity;2.02329086266882e-13!GO:0042623;ATPase activity, coupled;2.66381291666281e-13!GO:0050136;NADH dehydrogenase (quinone) activity;2.75475771618489e-13!GO:0003954;NADH dehydrogenase activity;2.75475771618489e-13!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.75475771618489e-13!GO:0048193;Golgi vesicle transport;2.76672714008323e-13!GO:0004386;helicase activity;3.03950297398536e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.00590386325584e-13!GO:0006399;tRNA metabolic process;4.0360775756931e-13!GO:0016192;vesicle-mediated transport;4.27859737563639e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.00798797262134e-13!GO:0016070;RNA metabolic process;6.351978259962e-13!GO:0006913;nucleocytoplasmic transport;7.4545328504184e-13!GO:0005789;endoplasmic reticulum membrane;9.61823020745537e-13!GO:0043687;post-translational protein modification;1.71259332656456e-12!GO:0051169;nuclear transport;1.85762938941029e-12!GO:0006732;coenzyme metabolic process;2.06106460967692e-12!GO:0051082;unfolded protein binding;2.08707077766852e-12!GO:0006446;regulation of translational initiation;2.54020078471574e-12!GO:0042775;organelle ATP synthesis coupled electron transport;8.67587722276057e-12!GO:0042773;ATP synthesis coupled electron transport;8.67587722276057e-12!GO:0016072;rRNA metabolic process;1.02893706586375e-11!GO:0006325;establishment and/or maintenance of chromatin architecture;1.06236869437589e-11!GO:0006364;rRNA processing;1.22264574289082e-11!GO:0006366;transcription from RNA polymerase II promoter;1.56702934694587e-11!GO:0030964;NADH dehydrogenase complex (quinone);2.35594939699057e-11!GO:0045271;respiratory chain complex I;2.35594939699057e-11!GO:0005747;mitochondrial respiratory chain complex I;2.35594939699057e-11!GO:0005643;nuclear pore;2.64998821515094e-11!GO:0008026;ATP-dependent helicase activity;2.74494158935926e-11!GO:0006323;DNA packaging;3.39206253054914e-11!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.0482480706073e-11!GO:0006461;protein complex assembly;5.44278361445575e-11!GO:0016604;nuclear body;5.98814488332529e-11!GO:0006403;RNA localization;6.9047881169838e-11!GO:0050657;nucleic acid transport;7.38265673042804e-11!GO:0051236;establishment of RNA localization;7.38265673042804e-11!GO:0050658;RNA transport;7.38265673042804e-11!GO:0008639;small protein conjugating enzyme activity;7.88193820188344e-11!GO:0000785;chromatin;8.21181548622619e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.60312443803078e-11!GO:0043067;regulation of programmed cell death;9.68343015449152e-11!GO:0042981;regulation of apoptosis;1.26301306721374e-10!GO:0003712;transcription cofactor activity;1.83216462753461e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.39453022366942e-10!GO:0004842;ubiquitin-protein ligase activity;2.64456620418703e-10!GO:0019787;small conjugating protein ligase activity;5.75279809390192e-10!GO:0017038;protein import;8.07119460994311e-10!GO:0048523;negative regulation of cellular process;1.00660497328165e-09!GO:0016787;hydrolase activity;1.1362103001107e-09!GO:0015630;microtubule cytoskeleton;1.46827886066054e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.46998062020236e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.46998062020236e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.46998062020236e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.69370714937274e-09!GO:0008565;protein transporter activity;2.05343564442992e-09!GO:0016740;transferase activity;2.23392919970439e-09!GO:0065002;intracellular protein transport across a membrane;2.24538098208788e-09!GO:0043038;amino acid activation;2.24538098208788e-09!GO:0006418;tRNA aminoacylation for protein translation;2.24538098208788e-09!GO:0043039;tRNA aminoacylation;2.24538098208788e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.57672411641511e-09!GO:0009055;electron carrier activity;2.83867987192565e-09!GO:0016779;nucleotidyltransferase activity;3.39536033680239e-09!GO:0005793;ER-Golgi intermediate compartment;3.7346246411258e-09!GO:0016881;acid-amino acid ligase activity;4.32842461928683e-09!GO:0065004;protein-DNA complex assembly;4.50689221248338e-09!GO:0046930;pore complex;4.88648835118992e-09!GO:0006333;chromatin assembly or disassembly;5.5645466518899e-09!GO:0051246;regulation of protein metabolic process;5.5645466518899e-09!GO:0051028;mRNA transport;6.1205540701566e-09!GO:0009060;aerobic respiration;7.09703363159566e-09!GO:0009259;ribonucleotide metabolic process;1.16393759097787e-08!GO:0005819;spindle;1.36896636963586e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.36896636963586e-08!GO:0006163;purine nucleotide metabolic process;1.39736356826921e-08!GO:0016607;nuclear speck;1.48850178728581e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.62075446977778e-08!GO:0006261;DNA-dependent DNA replication;1.71956242319311e-08!GO:0005768;endosome;1.77973825640731e-08!GO:0009056;catabolic process;2.60398690112794e-08!GO:0007005;mitochondrion organization and biogenesis;3.55196719471898e-08!GO:0006793;phosphorus metabolic process;3.71764524637182e-08!GO:0006796;phosphate metabolic process;3.71764524637182e-08!GO:0000775;chromosome, pericentric region;4.57221949659823e-08!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;4.86538865701212e-08!GO:0048519;negative regulation of biological process;5.77301093238908e-08!GO:0015986;ATP synthesis coupled proton transport;6.6106870920564e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.6106870920564e-08!GO:0006164;purine nucleotide biosynthetic process;6.81284582934157e-08!GO:0051188;cofactor biosynthetic process;6.90787816674537e-08!GO:0045333;cellular respiration;9.86992427821808e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.0190450234598e-07!GO:0009150;purine ribonucleotide metabolic process;1.19630946688446e-07!GO:0009260;ribonucleotide biosynthetic process;1.24498814810501e-07!GO:0043566;structure-specific DNA binding;1.3234176883451e-07!GO:0043623;cellular protein complex assembly;1.41094710253988e-07!GO:0043069;negative regulation of programmed cell death;1.53070381346521e-07!GO:0032446;protein modification by small protein conjugation;1.57955501365467e-07!GO:0016567;protein ubiquitination;2.04440460516248e-07!GO:0016568;chromatin modification;2.08144092617653e-07!GO:0019829;cation-transporting ATPase activity;2.13410112076843e-07!GO:0044431;Golgi apparatus part;2.4597573117067e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;2.4715094451102e-07!GO:0006916;anti-apoptosis;2.66040649770849e-07!GO:0007051;spindle organization and biogenesis;2.83037972726964e-07!GO:0009141;nucleoside triphosphate metabolic process;3.06927711130703e-07!GO:0000075;cell cycle checkpoint;3.32263204191328e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.46670536610058e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.46670536610058e-07!GO:0051170;nuclear import;3.60598327846576e-07!GO:0009199;ribonucleoside triphosphate metabolic process;4.48150420343563e-07!GO:0043066;negative regulation of apoptosis;4.65694386787695e-07!GO:0046034;ATP metabolic process;5.56785307138364e-07!GO:0009152;purine ribonucleotide biosynthetic process;5.81001300870992e-07!GO:0003697;single-stranded DNA binding;6.00554467672558e-07!GO:0003924;GTPase activity;7.19551675237226e-07!GO:0006752;group transfer coenzyme metabolic process;7.72227460727237e-07!GO:0031324;negative regulation of cellular metabolic process;7.72227460727237e-07!GO:0006099;tricarboxylic acid cycle;7.72866051548893e-07!GO:0046356;acetyl-CoA catabolic process;7.72866051548893e-07!GO:0005839;proteasome core complex (sensu Eukaryota);8.10249981408046e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;8.42560942770985e-07!GO:0009144;purine nucleoside triphosphate metabolic process;8.42560942770985e-07!GO:0051329;interphase of mitotic cell cycle;8.42560942770985e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;8.74955428483102e-07!GO:0006888;ER to Golgi vesicle-mediated transport;9.18723415071937e-07!GO:0005813;centrosome;9.28673357493837e-07!GO:0005667;transcription factor complex;9.28673357493837e-07!GO:0016310;phosphorylation;9.45184783750897e-07!GO:0006606;protein import into nucleus;9.66933408893542e-07!GO:0006754;ATP biosynthetic process;1.02536851057619e-06!GO:0006753;nucleoside phosphate metabolic process;1.02536851057619e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.09040310729507e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.11326284544133e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.11326284544133e-06!GO:0051325;interphase;1.17761749068163e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.22821275186745e-06!GO:0005815;microtubule organizing center;1.22821275186745e-06!GO:0009108;coenzyme biosynthetic process;1.26671329168861e-06!GO:0005657;replication fork;1.26809818606602e-06!GO:0030532;small nuclear ribonucleoprotein complex;1.32959268137823e-06!GO:0003724;RNA helicase activity;1.58010640304502e-06!GO:0048522;positive regulation of cellular process;1.58891581826604e-06!GO:0007010;cytoskeleton organization and biogenesis;1.60007663222249e-06!GO:0006334;nucleosome assembly;1.68889315412935e-06!GO:0048475;coated membrane;1.7201593656683e-06!GO:0030117;membrane coat;1.7201593656683e-06!GO:0045786;negative regulation of progression through cell cycle;1.90696412453e-06!GO:0006084;acetyl-CoA metabolic process;1.94696313743503e-06!GO:0030120;vesicle coat;1.96958717579919e-06!GO:0030662;coated vesicle membrane;1.96958717579919e-06!GO:0000245;spliceosome assembly;1.97852873899105e-06!GO:0009117;nucleotide metabolic process;1.99117012856905e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.12822594832119e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.12822594832119e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.15056911461514e-06!GO:0019899;enzyme binding;2.16538038275933e-06!GO:0007088;regulation of mitosis;2.21235672329711e-06!GO:0009109;coenzyme catabolic process;2.2593375961391e-06!GO:0016563;transcription activator activity;2.33194521737522e-06!GO:0031497;chromatin assembly;2.73585220592537e-06!GO:0004298;threonine endopeptidase activity;3.06402130489344e-06!GO:0003713;transcription coactivator activity;3.19364967155488e-06!GO:0007243;protein kinase cascade;3.54574056453544e-06!GO:0009892;negative regulation of metabolic process;3.55682408899324e-06!GO:0005525;GTP binding;3.90066694690092e-06!GO:0003899;DNA-directed RNA polymerase activity;3.92768449655749e-06!GO:0050794;regulation of cellular process;4.79332327083933e-06!GO:0045259;proton-transporting ATP synthase complex;5.51635944683133e-06!GO:0044440;endosomal part;5.54399342508792e-06!GO:0010008;endosome membrane;5.54399342508792e-06!GO:0006613;cotranslational protein targeting to membrane;7.50213965797014e-06!GO:0008094;DNA-dependent ATPase activity;7.67267672235034e-06!GO:0051187;cofactor catabolic process;8.07165953168943e-06!GO:0000151;ubiquitin ligase complex;8.07998131129197e-06!GO:0005762;mitochondrial large ribosomal subunit;1.06755594654151e-05!GO:0000315;organellar large ribosomal subunit;1.06755594654151e-05!GO:0016853;isomerase activity;1.25753060146472e-05!GO:0000139;Golgi membrane;1.39985588889505e-05!GO:0006950;response to stress;1.87390728655777e-05!GO:0051168;nuclear export;1.98258326184249e-05!GO:0065009;regulation of a molecular function;2.37584831188558e-05!GO:0051427;hormone receptor binding;3.00495195729805e-05!GO:0005770;late endosome;3.27204533609721e-05!GO:0003690;double-stranded DNA binding;3.32777807990294e-05!GO:0006302;double-strand break repair;3.38752491374616e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.56979720166341e-05!GO:0043021;ribonucleoprotein binding;3.89818856655614e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;3.93112705999355e-05!GO:0008033;tRNA processing;3.9743581117305e-05!GO:0005798;Golgi-associated vesicle;5.07596986958566e-05!GO:0044452;nucleolar part;5.07833250240869e-05!GO:0016363;nuclear matrix;5.1401053727201e-05!GO:0032561;guanyl ribonucleotide binding;5.231129156879e-05!GO:0019001;guanyl nucleotide binding;5.231129156879e-05!GO:0008186;RNA-dependent ATPase activity;5.94464300696384e-05!GO:0007059;chromosome segregation;6.52884895860989e-05!GO:0035257;nuclear hormone receptor binding;6.59902262044035e-05!GO:0051052;regulation of DNA metabolic process;6.70319590270551e-05!GO:0031988;membrane-bound vesicle;8.0879602125884e-05!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.21666556019006e-05!GO:0016023;cytoplasmic membrane-bound vesicle;8.56098116742576e-05!GO:0005773;vacuole;0.000102590338860213!GO:0000314;organellar small ribosomal subunit;0.000104502249194735!GO:0005763;mitochondrial small ribosomal subunit;0.000104502249194735!GO:0051252;regulation of RNA metabolic process;0.000108525826379689!GO:0000776;kinetochore;0.000110465276276996!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000114840376149874!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000129411632060174!GO:0007093;mitotic cell cycle checkpoint;0.000134032282505109!GO:0030036;actin cytoskeleton organization and biogenesis;0.000143051728234086!GO:0008654;phospholipid biosynthetic process;0.000165354151929344!GO:0016859;cis-trans isomerase activity;0.000170637445429301!GO:0004004;ATP-dependent RNA helicase activity;0.000173844930796994!GO:0009967;positive regulation of signal transduction;0.000187481562655478!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000187481562655478!GO:0045941;positive regulation of transcription;0.000200756206995956!GO:0043681;protein import into mitochondrion;0.000209310449888027!GO:0005769;early endosome;0.000211646591372052!GO:0031252;leading edge;0.000213512147381839!GO:0000323;lytic vacuole;0.000224078123538832!GO:0005764;lysosome;0.000224078123538832!GO:0042802;identical protein binding;0.000225778980621828!GO:0045454;cell redox homeostasis;0.00023444082549017!GO:0006612;protein targeting to membrane;0.000244959861440846!GO:0007052;mitotic spindle organization and biogenesis;0.000247656216069904!GO:0045893;positive regulation of transcription, DNA-dependent;0.000247656216069904!GO:0016564;transcription repressor activity;0.000250522297190426!GO:0030867;rough endoplasmic reticulum membrane;0.000254991940265732!GO:0003714;transcription corepressor activity;0.000285527007883335!GO:0019843;rRNA binding;0.000308987473818363!GO:0003729;mRNA binding;0.000319217542368994!GO:0006626;protein targeting to mitochondrion;0.000328505227210728!GO:0043065;positive regulation of apoptosis;0.000342266304233893!GO:0005788;endoplasmic reticulum lumen;0.000358129518305094!GO:0031982;vesicle;0.000397688256314649!GO:0031968;organelle outer membrane;0.000428955972531944!GO:0006402;mRNA catabolic process;0.000451296565642627!GO:0003678;DNA helicase activity;0.000462125854392067!GO:0006401;RNA catabolic process;0.000472321193644397!GO:0005048;signal sequence binding;0.000493524622340487!GO:0006310;DNA recombination;0.00050719143738854!GO:0043068;positive regulation of programmed cell death;0.00050917485727444!GO:0000059;protein import into nucleus, docking;0.000515258431215567!GO:0031410;cytoplasmic vesicle;0.000539100177505796!GO:0016491;oxidoreductase activity;0.000550813972586661!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000553230578732157!GO:0048471;perinuclear region of cytoplasm;0.00055426416274506!GO:0008250;oligosaccharyl transferase complex;0.00055848508902752!GO:0003682;chromatin binding;0.000559664930599963!GO:0019867;outer membrane;0.000565913226483742!GO:0003684;damaged DNA binding;0.000573186526095165!GO:0048518;positive regulation of biological process;0.000586819350793441!GO:0033116;ER-Golgi intermediate compartment membrane;0.00058748270520415!GO:0000082;G1/S transition of mitotic cell cycle;0.000589194957229883!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000606671051626852!GO:0006383;transcription from RNA polymerase III promoter;0.000631575193513717!GO:0000049;tRNA binding;0.000675118771727775!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000680319680384574!GO:0000786;nucleosome;0.000739951011647609!GO:0008092;cytoskeletal protein binding;0.000772020631216853!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000803385260997624!GO:0009112;nucleobase metabolic process;0.000805245525956752!GO:0004576;oligosaccharyl transferase activity;0.000825283042780149!GO:0046483;heterocycle metabolic process;0.000830105782733605!GO:0006414;translational elongation;0.000861674983680969!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000866834172941576!GO:0050790;regulation of catalytic activity;0.000867401998213546!GO:0005791;rough endoplasmic reticulum;0.000878207936105282!GO:0005885;Arp2/3 protein complex;0.000932886675890841!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00095126492350529!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00096156564427233!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000967882989567202!GO:0030029;actin filament-based process;0.000985706833140274!GO:0016481;negative regulation of transcription;0.000992763528171957!GO:0006417;regulation of translation;0.000999749478928612!GO:0007017;microtubule-based process;0.00103655739703604!GO:0030176;integral to endoplasmic reticulum membrane;0.00107816351005704!GO:0006839;mitochondrial transport;0.00109847995843018!GO:0007264;small GTPase mediated signal transduction;0.00111585766337821!GO:0016126;sterol biosynthetic process;0.00116440023608512!GO:0016044;membrane organization and biogenesis;0.00116440023608512!GO:0051920;peroxiredoxin activity;0.00124171044131485!GO:0006091;generation of precursor metabolites and energy;0.00124976580478045!GO:0005741;mitochondrial outer membrane;0.00126654917861197!GO:0004674;protein serine/threonine kinase activity;0.00126945850273352!GO:0015980;energy derivation by oxidation of organic compounds;0.00127301692426138!GO:0006275;regulation of DNA replication;0.00132170118421321!GO:0051338;regulation of transferase activity;0.00139509579673051!GO:0032508;DNA duplex unwinding;0.00140179899600386!GO:0032392;DNA geometric change;0.00140179899600386!GO:0030880;RNA polymerase complex;0.00144523216610775!GO:0005874;microtubule;0.0014657089819089!GO:0050662;coenzyme binding;0.00146940177139091!GO:0048500;signal recognition particle;0.00149972311980916!GO:0005876;spindle microtubule;0.00161096122603746!GO:0018196;peptidyl-asparagine modification;0.0017454452860597!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0017454452860597!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00176099122271509!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00176099122271509!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00176099122271509!GO:0043488;regulation of mRNA stability;0.00183783674981301!GO:0043487;regulation of RNA stability;0.00183783674981301!GO:0006352;transcription initiation;0.00185162346947464!GO:0008632;apoptotic program;0.00201766088588147!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00203616996004293!GO:0043596;nuclear replication fork;0.00204076791381437!GO:0006405;RNA export from nucleus;0.00204178553617833!GO:0043549;regulation of kinase activity;0.00232814464249097!GO:0006695;cholesterol biosynthetic process;0.00243958928193151!GO:0005905;coated pit;0.00245684888853855!GO:0008168;methyltransferase activity;0.00254985726275266!GO:0006268;DNA unwinding during replication;0.00281281736853524!GO:0030132;clathrin coat of coated pit;0.00285134038575629!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00289232507531979!GO:0000428;DNA-directed RNA polymerase complex;0.00289232507531979!GO:0030118;clathrin coat;0.00293914994478496!GO:0007050;cell cycle arrest;0.00294371035527091!GO:0008361;regulation of cell size;0.00301120305778812!GO:0005637;nuclear inner membrane;0.00303478281749008!GO:0008312;7S RNA binding;0.0030468426975003!GO:0016741;transferase activity, transferring one-carbon groups;0.00311256287612706!GO:0005684;U2-dependent spliceosome;0.00316171971685213!GO:0051789;response to protein stimulus;0.00316543882704892!GO:0006986;response to unfolded protein;0.00316543882704892!GO:0031072;heat shock protein binding;0.00323043670323193!GO:0006891;intra-Golgi vesicle-mediated transport;0.00325130848700911!GO:0008243;plasminogen activator activity;0.0033160525228262!GO:0007006;mitochondrial membrane organization and biogenesis;0.00342685303757535!GO:0016272;prefoldin complex;0.00343852615838029!GO:0001889;liver development;0.00347508187099881!GO:0001558;regulation of cell growth;0.00363637514050055!GO:0030133;transport vesicle;0.00366151699379189!GO:0042770;DNA damage response, signal transduction;0.00369101444641452!GO:0004518;nuclease activity;0.00370541279706945!GO:0016197;endosome transport;0.00384032245622861!GO:0051287;NAD binding;0.00389188073504387!GO:0051087;chaperone binding;0.00389372152724489!GO:0006611;protein export from nucleus;0.00392595316698906!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00393612325691127!GO:0045047;protein targeting to ER;0.00393612325691127!GO:0016049;cell growth;0.00397392359933722!GO:0050789;regulation of biological process;0.00403749342204026!GO:0030521;androgen receptor signaling pathway;0.00415860640054523!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00416621412416962!GO:0009889;regulation of biosynthetic process;0.00416621412416962!GO:0006520;amino acid metabolic process;0.00430894705980208!GO:0009116;nucleoside metabolic process;0.00430894705980208!GO:0019752;carboxylic acid metabolic process;0.00439538818643387!GO:0008180;signalosome;0.00446305900886328!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00452410850524991!GO:0015399;primary active transmembrane transporter activity;0.00452410850524991!GO:0006984;ER-nuclear signaling pathway;0.00466027018947172!GO:0031326;regulation of cellular biosynthetic process;0.00478776559228935!GO:0004527;exonuclease activity;0.0048591004453453!GO:0006082;organic acid metabolic process;0.00489166801829898!GO:0045859;regulation of protein kinase activity;0.00504089927622597!GO:0009165;nucleotide biosynthetic process;0.00525682391157011!GO:0035258;steroid hormone receptor binding;0.00530623525653068!GO:0016251;general RNA polymerase II transcription factor activity;0.00530756966436932!GO:0003711;transcription elongation regulator activity;0.00545470720786675!GO:0043022;ribosome binding;0.00546776338799774!GO:0008234;cysteine-type peptidase activity;0.00548108665863168!GO:0006144;purine base metabolic process;0.00548826316254697!GO:0031124;mRNA 3'-end processing;0.00549827166589745!GO:0015992;proton transport;0.00549827166589745!GO:0008047;enzyme activator activity;0.00559488636243518!GO:0008637;apoptotic mitochondrial changes;0.00559571170151942!GO:0006818;hydrogen transport;0.00571405558162123!GO:0008139;nuclear localization sequence binding;0.00585318173719598!GO:0008629;induction of apoptosis by intracellular signals;0.00600074342860492!GO:0000922;spindle pole;0.00600074342860492!GO:0009893;positive regulation of metabolic process;0.00612192040363233!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00612192040363233!GO:0008610;lipid biosynthetic process;0.00635256174801291!GO:0046467;membrane lipid biosynthetic process;0.00637632946228214!GO:0008022;protein C-terminus binding;0.00651214010835823!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00676940113288523!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00676940113288523!GO:0048468;cell development;0.00718742631904337!GO:0033673;negative regulation of kinase activity;0.00745878021488314!GO:0006469;negative regulation of protein kinase activity;0.00745878021488314!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00749732349157229!GO:0048487;beta-tubulin binding;0.00763055682347818!GO:0006509;membrane protein ectodomain proteolysis;0.00767315179427325!GO:0033619;membrane protein proteolysis;0.00767315179427325!GO:0003746;translation elongation factor activity;0.00776785619278522!GO:0042393;histone binding;0.00787682345432189!GO:0030658;transport vesicle membrane;0.00787682345432189!GO:0046489;phosphoinositide biosynthetic process;0.00831910961324159!GO:0006284;base-excision repair;0.00840865978886039!GO:0009119;ribonucleoside metabolic process;0.00872964057880036!GO:0016791;phosphoric monoester hydrolase activity;0.0091175323999607!GO:0030119;AP-type membrane coat adaptor complex;0.0091175323999607!GO:0006289;nucleotide-excision repair;0.00949076121593103!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00968813742531668!GO:0006270;DNA replication initiation;0.00985678607365749!GO:0006892;post-Golgi vesicle-mediated transport;0.00995202757449781!GO:0000792;heterochromatin;0.00997141674306084!GO:0005856;cytoskeleton;0.0100200814398172!GO:0016301;kinase activity;0.0100801505985536!GO:0045045;secretory pathway;0.010281159309122!GO:0009451;RNA modification;0.0104865974042777!GO:0048146;positive regulation of fibroblast proliferation;0.0104978445788615!GO:0043601;nuclear replisome;0.0105945118210698!GO:0030894;replisome;0.0105945118210698!GO:0051348;negative regulation of transferase activity;0.0109698296076468!GO:0006595;polyamine metabolic process;0.0110893393579536!GO:0000086;G2/M transition of mitotic cell cycle;0.0110893393579536!GO:0005832;chaperonin-containing T-complex;0.0111360472559789!GO:0046983;protein dimerization activity;0.0111693798507221!GO:0006917;induction of apoptosis;0.011183528925226!GO:0046474;glycerophospholipid biosynthetic process;0.0112797914931335!GO:0016311;dephosphorylation;0.0115682315511359!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0115751723626197!GO:0006497;protein amino acid lipidation;0.0117699744884895!GO:0030659;cytoplasmic vesicle membrane;0.0121819897498867!GO:0043624;cellular protein complex disassembly;0.012406066360323!GO:0030663;COPI coated vesicle membrane;0.0124090185323657!GO:0030126;COPI vesicle coat;0.0124090185323657!GO:0000339;RNA cap binding;0.0126330712912017!GO:0017166;vinculin binding;0.0130351518524518!GO:0006506;GPI anchor biosynthetic process;0.0131594029346026!GO:0048144;fibroblast proliferation;0.0133365669676446!GO:0048145;regulation of fibroblast proliferation;0.0133365669676446!GO:0032984;macromolecular complex disassembly;0.0134716444682617!GO:0000070;mitotic sister chromatid segregation;0.0135226430972591!GO:0000228;nuclear chromosome;0.0137724910966032!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0137724910966032!GO:0004003;ATP-dependent DNA helicase activity;0.0138287144191322!GO:0031570;DNA integrity checkpoint;0.0138287144191322!GO:0006400;tRNA modification;0.0139716134050867!GO:0000819;sister chromatid segregation;0.0139740927634006!GO:0001726;ruffle;0.0145220829785585!GO:0016584;nucleosome positioning;0.0145220829785585!GO:0030131;clathrin adaptor complex;0.0146009035942852!GO:0006376;mRNA splice site selection;0.0146009035942852!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0146009035942852!GO:0012502;induction of programmed cell death;0.0146588144795252!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0153018792840042!GO:0045936;negative regulation of phosphate metabolic process;0.0153856073818648!GO:0030125;clathrin vesicle coat;0.0154462427754849!GO:0030665;clathrin coated vesicle membrane;0.0154462427754849!GO:0006213;pyrimidine nucleoside metabolic process;0.0156832766636349!GO:0016408;C-acyltransferase activity;0.0158132748613997!GO:0006378;mRNA polyadenylation;0.0158952056563549!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0160663505894548!GO:0046966;thyroid hormone receptor binding;0.016095716861446!GO:0031902;late endosome membrane;0.0161346088945937!GO:0030134;ER to Golgi transport vesicle;0.0162225673943319!GO:0030660;Golgi-associated vesicle membrane;0.0162693065056601!GO:0005869;dynactin complex;0.0163099101824321!GO:0000725;recombinational repair;0.0164099590032235!GO:0000724;double-strand break repair via homologous recombination;0.0164099590032235!GO:0051540;metal cluster binding;0.0164306006069913!GO:0051536;iron-sulfur cluster binding;0.0164306006069913!GO:0051053;negative regulation of DNA metabolic process;0.0164937691183848!GO:0030833;regulation of actin filament polymerization;0.0166350406285054!GO:0032200;telomere organization and biogenesis;0.0169439690845698!GO:0000723;telomere maintenance;0.0169439690845698!GO:0042026;protein refolding;0.0173923971451346!GO:0004721;phosphoprotein phosphatase activity;0.0174084478897308!GO:0046822;regulation of nucleocytoplasmic transport;0.0174084478897308!GO:0006672;ceramide metabolic process;0.0177424453782315!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0179338662667177!GO:0015631;tubulin binding;0.0182969318539136!GO:0045792;negative regulation of cell size;0.0182969318539136!GO:0031123;RNA 3'-end processing;0.0182969318539136!GO:0000118;histone deacetylase complex;0.0182969318539136!GO:0051656;establishment of organelle localization;0.0184408235951254!GO:0043241;protein complex disassembly;0.0185726292538502!GO:0006740;NADPH regeneration;0.0188135756229324!GO:0006098;pentose-phosphate shunt;0.0188135756229324!GO:0006505;GPI anchor metabolic process;0.0188730530501043!GO:0007242;intracellular signaling cascade;0.0191251508175003!GO:0006338;chromatin remodeling;0.019873740206193!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0199110266168454!GO:0030308;negative regulation of cell growth;0.0199387140098405!GO:0022890;inorganic cation transmembrane transporter activity;0.0208377206458708!GO:0043492;ATPase activity, coupled to movement of substances;0.0209464653032605!GO:0030137;COPI-coated vesicle;0.0209909722355536!GO:0048037;cofactor binding;0.0210996613137892!GO:0000152;nuclear ubiquitin ligase complex;0.021341079864749!GO:0031529;ruffle organization and biogenesis;0.0215363205786959!GO:0008538;proteasome activator activity;0.0216959018746717!GO:0000910;cytokinesis;0.0221166156313561!GO:0004177;aminopeptidase activity;0.0223399335050742!GO:0030384;phosphoinositide metabolic process;0.0227939982478212!GO:0022406;membrane docking;0.0230019416267007!GO:0048278;vesicle docking;0.0230019416267007!GO:0008283;cell proliferation;0.0230716760504177!GO:0030127;COPII vesicle coat;0.0231439107331165!GO:0012507;ER to Golgi transport vesicle membrane;0.0231439107331165!GO:0008097;5S rRNA binding;0.0234434772181855!GO:0051059;NF-kappaB binding;0.0236139004132559!GO:0046519;sphingoid metabolic process;0.0242774330472432!GO:0051539;4 iron, 4 sulfur cluster binding;0.0242774330472432!GO:0031325;positive regulation of cellular metabolic process;0.0246799974603608!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.025130360305203!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.025242999698387!GO:0031575;G1/S transition checkpoint;0.0252874894003591!GO:0000726;non-recombinational repair;0.0253044433860951!GO:0046128;purine ribonucleoside metabolic process;0.0255946142490668!GO:0042278;purine nucleoside metabolic process;0.0255946142490668!GO:0050681;androgen receptor binding;0.0256047862832143!GO:0007034;vacuolar transport;0.0259887134508154!GO:0004860;protein kinase inhibitor activity;0.0266190639704039!GO:0042326;negative regulation of phosphorylation;0.0267880467930471!GO:0004680;casein kinase activity;0.0267880467930471!GO:0031901;early endosome membrane;0.0268159367994992!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0278578099608766!GO:0010257;NADH dehydrogenase complex assembly;0.0278578099608766!GO:0033108;mitochondrial respiratory chain complex assembly;0.0278578099608766!GO:0008408;3'-5' exonuclease activity;0.0279458686982002!GO:0051716;cellular response to stimulus;0.0284823970953335!GO:0006650;glycerophospholipid metabolic process;0.0285399898574754!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0286855682018157!GO:0031625;ubiquitin protein ligase binding;0.0288176111253118!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0288593981400332!GO:0005092;GDP-dissociation inhibitor activity;0.0301607934319931!GO:0030518;steroid hormone receptor signaling pathway;0.0306100680840886!GO:0016407;acetyltransferase activity;0.0307422382814108!GO:0043189;H4/H2A histone acetyltransferase complex;0.0308188378947825!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0316868295049713!GO:0032906;transforming growth factor-beta2 production;0.0316868295049713!GO:0032909;regulation of transforming growth factor-beta2 production;0.0316868295049713!GO:0000178;exosome (RNase complex);0.0316868295049713!GO:0030433;ER-associated protein catabolic process;0.031761119146057!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.031761119146057!GO:0031577;spindle checkpoint;0.031761119146057!GO:0043433;negative regulation of transcription factor activity;0.0318377708702745!GO:0008536;Ran GTPase binding;0.0323471034256659!GO:0003779;actin binding;0.0324803464812582!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0333827052885148!GO:0005862;muscle thin filament tropomyosin;0.0333908685403375!GO:0019222;regulation of metabolic process;0.0335817454879855!GO:0042158;lipoprotein biosynthetic process;0.0336805638642507!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0339609570867393!GO:0045039;protein import into mitochondrial inner membrane;0.0339609570867393!GO:0009303;rRNA transcription;0.0339778436874641!GO:0047485;protein N-terminus binding;0.0339940882299832!GO:0017134;fibroblast growth factor binding;0.0341735401636951!GO:0040008;regulation of growth;0.0342037157602554!GO:0044433;cytoplasmic vesicle part;0.0342719699232653!GO:0005784;translocon complex;0.0345956670517213!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0353259828610272!GO:0003725;double-stranded RNA binding;0.0358691032339666!GO:0003702;RNA polymerase II transcription factor activity;0.0365385432787249!GO:0006360;transcription from RNA polymerase I promoter;0.0369402107135554!GO:0035267;NuA4 histone acetyltransferase complex;0.0372539539035799!GO:0007021;tubulin folding;0.0373361770071939!GO:0046112;nucleobase biosynthetic process;0.0374597438582771!GO:0000209;protein polyubiquitination;0.0374597438582771!GO:0006904;vesicle docking during exocytosis;0.037737302049404!GO:0032259;methylation;0.0378904640241372!GO:0044454;nuclear chromosome part;0.0379000341095747!GO:0019783;small conjugating protein-specific protease activity;0.0386090963048578!GO:0003887;DNA-directed DNA polymerase activity;0.038700422658602!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0387701052129497!GO:0015002;heme-copper terminal oxidase activity;0.0387701052129497!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0387701052129497!GO:0004129;cytochrome-c oxidase activity;0.0387701052129497!GO:0019901;protein kinase binding;0.0388022667555783!GO:0000077;DNA damage checkpoint;0.0389048797810029!GO:0012506;vesicle membrane;0.0406898125495234!GO:0007004;telomere maintenance via telomerase;0.0407870998437715!GO:0043414;biopolymer methylation;0.0408173272772129!GO:0019887;protein kinase regulator activity;0.0408396218858506!GO:0046982;protein heterodimerization activity;0.0411772633170939!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0413604663118533!GO:0043284;biopolymer biosynthetic process;0.0414977429788341!GO:0045892;negative regulation of transcription, DNA-dependent;0.041655083455168!GO:0000096;sulfur amino acid metabolic process;0.0425275092940853!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0426471009289914!GO:0044262;cellular carbohydrate metabolic process;0.0429008813278287!GO:0001836;release of cytochrome c from mitochondria;0.0433324337428549!GO:0006897;endocytosis;0.0435573885446171!GO:0010324;membrane invagination;0.0435573885446171!GO:0005663;DNA replication factor C complex;0.0437121544224335!GO:0007162;negative regulation of cell adhesion;0.0437714491079187!GO:0051128;regulation of cellular component organization and biogenesis;0.044105946376421!GO:0051090;regulation of transcription factor activity;0.0443733854339041!GO:0022408;negative regulation of cell-cell adhesion;0.0445539197110687!GO:0030155;regulation of cell adhesion;0.0445539197110687!GO:0043154;negative regulation of caspase activity;0.0445539197110687!GO:0005669;transcription factor TFIID complex;0.0447177572652994!GO:0008156;negative regulation of DNA replication;0.0451494833693057!GO:0005096;GTPase activator activity;0.0453028021001086!GO:0044438;microbody part;0.0457452683742851!GO:0044439;peroxisomal part;0.0457452683742851!GO:0004659;prenyltransferase activity;0.0461040724545941!GO:0019207;kinase regulator activity;0.0465543334437013!GO:0004843;ubiquitin-specific protease activity;0.0466005939079284!GO:0003923;GPI-anchor transamidase activity;0.0466005939079284!GO:0016255;attachment of GPI anchor to protein;0.0466005939079284!GO:0042765;GPI-anchor transamidase complex;0.0466005939079284!GO:0005938;cell cortex;0.0466005939079284!GO:0003756;protein disulfide isomerase activity;0.0466005939079284!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0466005939079284!GO:0004532;exoribonuclease activity;0.0466005939079284!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0466005939079284!GO:0040029;regulation of gene expression, epigenetic;0.0469867347164214!GO:0008426;protein kinase C inhibitor activity;0.0471078327049782!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0475701735055923!GO:0051098;regulation of binding;0.0477217351748915!GO:0051101;regulation of DNA binding;0.0479574510797614!GO:0045926;negative regulation of growth;0.0480492309421823!GO:0019206;nucleoside kinase activity;0.0481739735805796!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0481739735805796!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0483530365612364!GO:0030968;unfolded protein response;0.0484108155277666!GO:0022411;cellular component disassembly;0.0485574359035127!GO:0043281;regulation of caspase activity;0.0488358747973961!GO:0007030;Golgi organization and biogenesis;0.0494256296245278
|sample_id=10432
|sample_id=10432
|sample_note=machine failed, remainder reloaded, low amount
|sample_note=machine failed, remainder reloaded, low amount
Line 76: Line 99:
|sample_tissue=bile duct
|sample_tissue=bile duct
|top_motifs=ZEB1:1.94414767736;SNAI1..3:1.84274580312;TBX4,5:1.52011256842;PPARG:1.3852545871;PITX1..3:1.32349339141;bHLH_family:1.29151362753;FOXA2:1.24138866202;E2F1..5:1.21053883561;ELK1,4_GABP{A,B1}:1.13057229559;MYB:1.12604259407;FOX{I1,J2}:1.0538006006;FOXD3:1.01373558874;ADNP_IRX_SIX_ZHX:0.945583154196;PAX8:0.935500684032;TFDP1:0.91783576886;TEAD1:0.910022058835;LEF1_TCF7_TCF7L1,2:0.890039038454;ARID5B:0.851716648914;NFY{A,B,C}:0.847396520552;MYOD1:0.812162514367;FOXQ1:0.654012018128;XCPE1{core}:0.649138417058;ZNF148:0.640732956986;NKX3-2:0.623782386287;ESRRA:0.593242503937;AHR_ARNT_ARNT2:0.537396943137;NKX2-2,8:0.473731768301;ELF1,2,4:0.458748155394;FOS_FOS{B,L1}_JUN{B,D}:0.451592389127;BACH2:0.446951437535;POU1F1:0.4290993361;CDC5L:0.424143341526;FOXP1:0.421983627735;VSX1,2:0.413258993819;ONECUT1,2:0.393824800496;HNF1A:0.388562131887;POU2F1..3:0.375623723151;CRX:0.357420352996;NKX2-3_NKX2-5:0.350083719939;OCT4_SOX2{dimer}:0.343058504901;SP1:0.339351773149;ZNF143:0.330542769535;NFE2:0.291407831027;IRF7:0.251794940157;HMGA1,2:0.236405127133;NR6A1:0.228642111694;NRF1:0.213832030588;LHX3,4:0.204040179334;SOX{8,9,10}:0.202612024118;LMO2:0.202597638235;BREu{core}:0.197682067802;HES1:0.188659586083;FOXN1:0.177305753313;FOXM1:0.111200547589;PAX5:0.101249339159;EN1,2:0.10020825534;NFKB1_REL_RELA:0.0977401362549;TFCP2:0.0918904861631;NR1H4:0.0845048930236;FOSL2:0.0839816727418;SOX2:0.0670730164378;POU5F1:0.0457315092244;RBPJ:0.0444608276227;ATF5_CREB3:0.0383709139343;MTF1:0.0295944811179;BPTF:0.0248572814224;IKZF1:0.01932829163;YY1:0.0187833154373;GATA6:0.0176717157234;HAND1,2:0.00409667268333;TEF:-0.00621293810979;PAX2:-0.0157109241114;EP300:-0.015899889166;HNF4A_NR2F1,2:-0.0172711529513;GFI1:-0.0199380989269;STAT5{A,B}:-0.0324361885765;HOX{A6,A7,B6,B7}:-0.0377249289065;HOX{A5,B5}:-0.0394633878003;HLF:-0.0529299431877;GLI1..3:-0.0538241729968;IRF1,2:-0.0882110904402;GCM1,2:-0.0953635315672;NKX6-1,2:-0.0974022395853;NFATC1..3:-0.108854587635;FOX{D1,D2}:-0.119149069968;HBP1_HMGB_SSRP1_UBTF:-0.131945947276;PDX1:-0.135684503106;MAZ:-0.137527474106;NANOG:-0.144918672763;ZFP161:-0.145158427668;SOX17:-0.154526933526;TFAP2B:-0.162685897746;ATF4:-0.170796003513;TP53:-0.193012449662;FOXO1,3,4:-0.193494369355;GTF2A1,2:-0.197491092856;TLX1..3_NFIC{dimer}:-0.199787761644;POU3F1..4:-0.216636547702;SPIB:-0.223847925497;ETS1,2:-0.233696248032;CEBPA,B_DDIT3:-0.23706368926;DBP:-0.240721445612;STAT2,4,6:-0.241340767392;MEF2{A,B,C,D}:-0.254146598181;HMX1:-0.28125050337;TBP:-0.283360935849;TFAP2{A,C}:-0.289998274544;ZBTB16:-0.293151423704;HIC1:-0.302441377118;ATF2:-0.303376644306;NFE2L2:-0.306547857752;PRDM1:-0.307223913597;MTE{core}:-0.312376431451;RFX1:-0.31387344055;NKX2-1,4:-0.314512010857;MED-1{core}:-0.314712202287;RUNX1..3:-0.333560515439;NR5A1,2:-0.348172367775;ZBTB6:-0.35673714233;CUX2:-0.362238193108;EGR1..3:-0.362671541886;XBP1:-0.393041753757;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.395277301106;JUN:-0.408190068047;FOXL1:-0.409782184425;TAL1_TCF{3,4,12}:-0.41144193298;SPI1:-0.413261737438;GZF1:-0.416493974096;RORA:-0.419501888889;NHLH1,2:-0.420253032418;ALX4:-0.424828270784;GFI1B:-0.462119287451;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.483870911719;EBF1:-0.487713537761;NR3C1:-0.487981095068;SRF:-0.489531929398;ZNF423:-0.491072322689;TOPORS:-0.509794113764;PBX1:-0.514621182698;IKZF2:-0.515109785301;AIRE:-0.521409513749;HSF1,2:-0.5230025728;EVI1:-0.529946516569;ZIC1..3:-0.530412144191;AR:-0.533373046885;RREB1:-0.533532145853;UFEwm:-0.542156022859;KLF4:-0.544816528842;RFX2..5_RFXANK_RFXAP:-0.54829529235;PRRX1,2:-0.549028151124;CREB1:-0.578603194853;NKX3-1:-0.593895405087;MYBL2:-0.609370752571;REST:-0.611496079019;ALX1:-0.628254348203;HIF1A:-0.629827533326;NFE2L1:-0.631549143252;DMAP1_NCOR{1,2}_SMARC:-0.63157242737;GTF2I:-0.6325784025;PATZ1:-0.65005575693;TLX2:-0.651452931728;HOXA9_MEIS1:-0.655861875101;NFIL3:-0.665704547193;MZF1:-0.668186150437;FOX{F1,F2,J1}:-0.687200653578;SREBF1,2:-0.736236624144;POU6F1:-0.746046624442;ATF6:-0.759751316301;CDX1,2,4:-0.763402487785;SPZ1:-0.764654691324;RXRA_VDR{dimer}:-0.781677345357;PAX3,7:-0.793520344212;PAX6:-0.80658610675;FOXP3:-0.819616115601;PAX4:-0.822177565515;ESR1:-0.827064041292;NFIX:-0.884562132034;MAFB:-0.898483187505;ZNF238:-0.903612464547;HOX{A4,D4}:-0.938655238831;SOX5:-0.956266913577;GATA4:-0.967426437992;TGIF1:-0.976201827329;MYFfamily:-1.00152335522;PAX1,9:-1.14467678765;T:-1.15114214774;NANOG{mouse}:-1.15175271819;ZNF384:-1.15215720502;RXR{A,B,G}:-1.19764577535;TFAP4:-1.20633217133;SMAD1..7,9:-1.49934560507;STAT1,3:-1.61188029896
|top_motifs=ZEB1:1.94414767736;SNAI1..3:1.84274580312;TBX4,5:1.52011256842;PPARG:1.3852545871;PITX1..3:1.32349339141;bHLH_family:1.29151362753;FOXA2:1.24138866202;E2F1..5:1.21053883561;ELK1,4_GABP{A,B1}:1.13057229559;MYB:1.12604259407;FOX{I1,J2}:1.0538006006;FOXD3:1.01373558874;ADNP_IRX_SIX_ZHX:0.945583154196;PAX8:0.935500684032;TFDP1:0.91783576886;TEAD1:0.910022058835;LEF1_TCF7_TCF7L1,2:0.890039038454;ARID5B:0.851716648914;NFY{A,B,C}:0.847396520552;MYOD1:0.812162514367;FOXQ1:0.654012018128;XCPE1{core}:0.649138417058;ZNF148:0.640732956986;NKX3-2:0.623782386287;ESRRA:0.593242503937;AHR_ARNT_ARNT2:0.537396943137;NKX2-2,8:0.473731768301;ELF1,2,4:0.458748155394;FOS_FOS{B,L1}_JUN{B,D}:0.451592389127;BACH2:0.446951437535;POU1F1:0.4290993361;CDC5L:0.424143341526;FOXP1:0.421983627735;VSX1,2:0.413258993819;ONECUT1,2:0.393824800496;HNF1A:0.388562131887;POU2F1..3:0.375623723151;CRX:0.357420352996;NKX2-3_NKX2-5:0.350083719939;OCT4_SOX2{dimer}:0.343058504901;SP1:0.339351773149;ZNF143:0.330542769535;NFE2:0.291407831027;IRF7:0.251794940157;HMGA1,2:0.236405127133;NR6A1:0.228642111694;NRF1:0.213832030588;LHX3,4:0.204040179334;SOX{8,9,10}:0.202612024118;LMO2:0.202597638235;BREu{core}:0.197682067802;HES1:0.188659586083;FOXN1:0.177305753313;FOXM1:0.111200547589;PAX5:0.101249339159;EN1,2:0.10020825534;NFKB1_REL_RELA:0.0977401362549;TFCP2:0.0918904861631;NR1H4:0.0845048930236;FOSL2:0.0839816727418;SOX2:0.0670730164378;POU5F1:0.0457315092244;RBPJ:0.0444608276227;ATF5_CREB3:0.0383709139343;MTF1:0.0295944811179;BPTF:0.0248572814224;IKZF1:0.01932829163;YY1:0.0187833154373;GATA6:0.0176717157234;HAND1,2:0.00409667268333;TEF:-0.00621293810979;PAX2:-0.0157109241114;EP300:-0.015899889166;HNF4A_NR2F1,2:-0.0172711529513;GFI1:-0.0199380989269;STAT5{A,B}:-0.0324361885765;HOX{A6,A7,B6,B7}:-0.0377249289065;HOX{A5,B5}:-0.0394633878003;HLF:-0.0529299431877;GLI1..3:-0.0538241729968;IRF1,2:-0.0882110904402;GCM1,2:-0.0953635315672;NKX6-1,2:-0.0974022395853;NFATC1..3:-0.108854587635;FOX{D1,D2}:-0.119149069968;HBP1_HMGB_SSRP1_UBTF:-0.131945947276;PDX1:-0.135684503106;MAZ:-0.137527474106;NANOG:-0.144918672763;ZFP161:-0.145158427668;SOX17:-0.154526933526;TFAP2B:-0.162685897746;ATF4:-0.170796003513;TP53:-0.193012449662;FOXO1,3,4:-0.193494369355;GTF2A1,2:-0.197491092856;TLX1..3_NFIC{dimer}:-0.199787761644;POU3F1..4:-0.216636547702;SPIB:-0.223847925497;ETS1,2:-0.233696248032;CEBPA,B_DDIT3:-0.23706368926;DBP:-0.240721445612;STAT2,4,6:-0.241340767392;MEF2{A,B,C,D}:-0.254146598181;HMX1:-0.28125050337;TBP:-0.283360935849;TFAP2{A,C}:-0.289998274544;ZBTB16:-0.293151423704;HIC1:-0.302441377118;ATF2:-0.303376644306;NFE2L2:-0.306547857752;PRDM1:-0.307223913597;MTE{core}:-0.312376431451;RFX1:-0.31387344055;NKX2-1,4:-0.314512010857;MED-1{core}:-0.314712202287;RUNX1..3:-0.333560515439;NR5A1,2:-0.348172367775;ZBTB6:-0.35673714233;CUX2:-0.362238193108;EGR1..3:-0.362671541886;XBP1:-0.393041753757;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.395277301106;JUN:-0.408190068047;FOXL1:-0.409782184425;TAL1_TCF{3,4,12}:-0.41144193298;SPI1:-0.413261737438;GZF1:-0.416493974096;RORA:-0.419501888889;NHLH1,2:-0.420253032418;ALX4:-0.424828270784;GFI1B:-0.462119287451;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.483870911719;EBF1:-0.487713537761;NR3C1:-0.487981095068;SRF:-0.489531929398;ZNF423:-0.491072322689;TOPORS:-0.509794113764;PBX1:-0.514621182698;IKZF2:-0.515109785301;AIRE:-0.521409513749;HSF1,2:-0.5230025728;EVI1:-0.529946516569;ZIC1..3:-0.530412144191;AR:-0.533373046885;RREB1:-0.533532145853;UFEwm:-0.542156022859;KLF4:-0.544816528842;RFX2..5_RFXANK_RFXAP:-0.54829529235;PRRX1,2:-0.549028151124;CREB1:-0.578603194853;NKX3-1:-0.593895405087;MYBL2:-0.609370752571;REST:-0.611496079019;ALX1:-0.628254348203;HIF1A:-0.629827533326;NFE2L1:-0.631549143252;DMAP1_NCOR{1,2}_SMARC:-0.63157242737;GTF2I:-0.6325784025;PATZ1:-0.65005575693;TLX2:-0.651452931728;HOXA9_MEIS1:-0.655861875101;NFIL3:-0.665704547193;MZF1:-0.668186150437;FOX{F1,F2,J1}:-0.687200653578;SREBF1,2:-0.736236624144;POU6F1:-0.746046624442;ATF6:-0.759751316301;CDX1,2,4:-0.763402487785;SPZ1:-0.764654691324;RXRA_VDR{dimer}:-0.781677345357;PAX3,7:-0.793520344212;PAX6:-0.80658610675;FOXP3:-0.819616115601;PAX4:-0.822177565515;ESR1:-0.827064041292;NFIX:-0.884562132034;MAFB:-0.898483187505;ZNF238:-0.903612464547;HOX{A4,D4}:-0.938655238831;SOX5:-0.956266913577;GATA4:-0.967426437992;TGIF1:-0.976201827329;MYFfamily:-1.00152335522;PAX1,9:-1.14467678765;T:-1.15114214774;NANOG{mouse}:-1.15175271819;ZNF384:-1.15215720502;RXR{A,B,G}:-1.19764577535;TFAP4:-1.20633217133;SMAD1..7,9:-1.49934560507;STAT1,3:-1.61188029896
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10432-106D9;search_select_hide=table117:FF:10432-106D9
}}
}}

Latest revision as of 14:01, 3 June 2020

Name:bile duct carcinoma cell line:HuCCT1
Species:Human (Homo sapiens)
Library ID:CNhs10750
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissuebile duct
dev stage56 year old adult
sexunknown
age56
cell typeduct cell, bile duct
cell lineHuCCT1
companyRIKEN Bioresource centre
collaborationYukio Nakamura (RIKEN BRC)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005118
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs10750 CAGE DRX007833 DRR008705
Accession ID Hg19

Library idBAMCTSS
CNhs10750 DRZ000130 DRZ001515
Accession ID Hg38

Library idBAMCTSS
CNhs10750 DRZ011480 DRZ012865
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)


Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis-0.0312
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.549
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
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C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample


JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs10750

Jaspar motifP-value
MA0002.20.302
MA0003.10.396
MA0004.10.889
MA0006.10.485
MA0007.10.488
MA0009.10.179
MA0014.10.0352
MA0017.10.676
MA0018.20.362
MA0019.10.166
MA0024.11.01958e-4
MA0025.10.698
MA0027.10.37
MA0028.11.57796e-6
MA0029.10.317
MA0030.10.13
MA0031.10.512
MA0035.20.00962
MA0038.10.134
MA0039.20.00314
MA0040.10.418
MA0041.10.929
MA0042.10.535
MA0043.10.93
MA0046.10.00122
MA0047.20.042
MA0048.10.35
MA0050.10.0784
MA0051.16.79664e-4
MA0052.10.478
MA0055.10.0035
MA0057.10.51
MA0058.10.673
MA0059.10.58
MA0060.16.95478e-5
MA0061.10.613
MA0062.24.58742e-6
MA0065.20.784
MA0066.10.588
MA0067.10.0928
MA0068.10.0334
MA0069.10.79
MA0070.10.522
MA0071.10.23
MA0072.10.747
MA0073.10.46
MA0074.10.635
MA0076.11.96464e-4
MA0077.10.687
MA0078.10.646
MA0079.20.804
MA0080.20.188
MA0081.10.622
MA0083.10.0366
MA0084.10.152
MA0087.10.898
MA0088.10.631
MA0090.10.00175
MA0091.10.00135
MA0092.10.307
MA0093.10.83
MA0099.22.71604e-11
MA0100.10.335
MA0101.10.628
MA0102.20.896
MA0103.13.64938e-9
MA0104.20.148
MA0105.10.0186
MA0106.10.806
MA0107.10.529
MA0108.20.429
MA0111.10.808
MA0112.20.512
MA0113.10.0346
MA0114.10.282
MA0115.10.251
MA0116.10.208
MA0117.10.311
MA0119.10.904
MA0122.10.727
MA0124.10.462
MA0125.10.466
MA0131.10.262
MA0135.10.394
MA0136.10.44
MA0137.20.321
MA0138.20.0246
MA0139.10.374
MA0140.10.117
MA0141.10.413
MA0142.10.748
MA0143.10.173
MA0144.10.644
MA0145.10.661
MA0146.10.374
MA0147.10.0592
MA0148.10.0667
MA0149.10.0943
MA0150.10.168
MA0152.10.181
MA0153.13.56894e-4
MA0154.10.0851
MA0155.10.0122
MA0156.10.0172
MA0157.10.472
MA0159.10.505
MA0160.10.709
MA0162.10.973
MA0163.10.0124
MA0164.10.753
MA0258.10.0418
MA0259.10.615



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs10750

Novel motifP-value
10.688
100.77
1000.306
1010.167
1020.641
1030.52
1040.791
1050.4
1060.912
1070.638
1080.922
1090.117
110.0887
1100.705
1110.802
1120.0492
1130.0269
1140.307
1150.236
1160.147
1170.694
1180.976
1190.232
120.595
1200.549
1210.139
1220.215
1230.771
1240.365
1250.309
1260.683
1270.996
1280.00119
1290.365
130.0545
1300.118
1310.41
1320.9
1330.0588
1340.468
1350.0301
1360.0151
1370.27
1380.884
1390.0622
140.77
1400.646
1410.0717
1420.787
1430.0846
1440.159
1450.395
1460.606
1470.781
1480.993
1490.149
150.76
1500.537
1510.743
1520.618
1530.291
1540.769
1550.276
1560.186
1570.453
1580.357
1590.58
160.695
1600.585
1610.935
1620.203
1630.611
1640.722
1650.37
1660.49
1670.965
1680.29
1690.986
170.614
180.188
190.2
20.629
200.0779
210.253
220.154
230.0849
240.415
250.852
260.36
270.637
280.487
290.3
30.23
300.609
310.194
321.84694e-4
330.12
340.165
350.106
360.546
370.461
380.985
390.57
40.918
400.452
410.213
420.91
430.161
440.441
450.974
460.273
470.992
480.589
490.178
50.33
500.176
510.561
520.75
530.525
540.409
550.782
560.713
570.833
580.759
590.33
60.493
600.877
610.293
620.179
630.222
640.303
650.184
660.0266
670.881
680.00293
690.438
70.492
700.142
710.533
720.231
730.585
740.898
750.531
760.514
770.745
780.106
790.0013
80.391
800.253
810.0242
823.57767e-5
830.164
840.576
850.0057
860.717
870.0119
880.523
890.255
90.127
900.477
910.122
920.088
930.759
940.0963
950.283
960.122
970.621
980.343
990.646



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs10750


FANTOM5 (FF) ontology


Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)

DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
7 (disease of anatomical entity)
305 (carcinoma)

UBERON: Anatomy
0000468 (multi-cellular organism)
0002394 (bile duct)
0000058 (duct)
0001007 (digestive system)
0004119 (endoderm-derived structure)
0000062 (organ)
0004111 (anatomical conduit)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003928 (digestive system duct)
0010317 (germ layer / neural crest derived structure)
0002294 (biliary system)
0001173 (biliary tree)
0002423 (hepatobiliary system)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0103910 (bile duct cancer cell line sample)
0103911 (HuCCT-1 cell sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0001041 (foregut)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0009497 (epithelium of foregut-midgut junction)
UBERON:0010316 (germ layer / neural crest)