FF:10485-107A8: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00006006 | ||
| | |accession_numbers=CAGE;DRX007899;DRR008771;DRZ000196;DRZ001581;DRZ011546;DRZ012931 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000955,UBERON:0004121,UBERON:0011216,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0010317,UBERON:0001017,UBERON:0001016 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002371,CL:0002319,CL:0000095,CL:0000243,CL:0000125,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:14566,DOID:3093 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0101530,FF:0100711,FF:0100255,FF:0100690,FF:0101531,FF:0101583 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
|def= | |||
|expression_enrichment_score=chr16:86544113..86544145,+!p1@FOXF1!1.90!95.37!FOXF1;;chr6:10415276..10415341,-!p2@TFAP2A!1.69!58.14!TFAP2A;;chr8:72756637..72756664,-!p3@MSC!1.58!41.51!MSC;;chr5:134369905..134369972,-!p1@PITX1!1.54!50.90!PITX1;;chr6:10412600..10412637,-!p1@TFAP2A!1.50!49.98!TFAP2A;;chr5:134369879..134369898,-!p2@PITX1!1.50!30.60!PITX1;;chr5:92919100..92919135,+!p3@NR2F1!1.49!36.01!NR2F1;;chr3:25470156..25470227,+!p2@RARB!1.43!26.01!RARB;;chr19:13134772..13134822,+!p2@NFIX!1.31!28.15!NFIX;;chr12:54380404..54380433,+!p3@HOXC10!1.30!18.77!HOXC10;;chr8:72756667..72756736,-!p2@MSC!1.29!28.56!MSC;;chr14:29235961..29236008,+!p1@FOXG1!1.29!18.46!FOXG1;;chr6:10412392..10412409,-!p4@TFAP2A!1.28!20.81!TFAP2A;;chr5:2751762..2751784,-!p1@IRX2!1.26!17.24!IRX2;;chr6:1389789..1389821,+!p1@FOXF2!1.24!22.64!FOXF2;;chr5:92918919..92918942,+!p1@NR2F1!1.22!68.64!NR2F1;;chr20:55204351..55204377,+!p1@TFAP2C!1.18!17.85!TFAP2C;;chr3:25469724..25469773,+!p1@RARB!1.15!18.87!RARB;;chr5:3595977..3595999,+!p1@IRX1!1.15!13.26!IRX1;;chr14:33403881..33403924,+!p1@NPAS3!1.12!12.04!NPAS3;;chr5:3595934..3595957,+!p2@IRX1!1.11!11.83!IRX1;;chr8:72756267..72756296,-!p4@MSC!1.09!16.52!MSC;;chr12:115121962..115121987,-!p1@TBX3!1.08!93.74!TBX3;;chr5:321810..321877,+!p1@AHRR!1.08!34.88!AHRR;;chr8:72756063..72756125,-!p1@MSC!1.08!22.64!MSC;;chr6:45390025..45390076,+!p2@RUNX2!1.06!25.40!RUNX2;;chr11:44331576..44331650,-!p1@ALX4!1.05!10.30!ALX4;;chrY:21906594..21906622,-!p1@KDM5D!1.05!10.10!KDM5D;;chr5:176738887..176738934,-!p1@MXD3!1.02!64.77!MXD3;;chr6:28321971..28321995,-!p1@ZNF323!1.02!9.59!ZNF323;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.02!9.38!HOXC5;;chr15:57511609..57511651,+!p2@TCF12!0.99!14.79!TCF12;;chr2:172949484..172949522,+!p1@DLX1!0.99!8.67!DLX1;;chr10:8095593..8095625,+!p3@GATA3!0.98!10.10!GATA3;;chrY:2803415..2803468,+!p1@ZFY!0.98!8.47!ZFY;;chr2:178128149..178128198,-!p2@NFE2L2!0.96!44.68!NFE2L2;;chr17:79881332..79881348,-!p3@MAFG!0.96!11.93!MAFG;;chr2:176994408..176994492,+!p1@HOXD8!0.96!8.06!HOXD8;;chr14:61116183..61116208,-!p1@SIX1!0.95!31.01!SIX1;;chr5:124082322..124082364,-!p1@ZNF608!0.95!20.71!ZNF608;;chr5:92919375..92919438,+!p6@NR2F1!0.94!8.36!NR2F1;;chr1:59249645..59249656,-!p4@JUN!0.93!19.38!JUN;;chrX:66763856..66763896,+!p1@AR!0.93!11.02!AR;;chr12:54332608..54332636,+!p1@HOXC13!0.93!7.45!HOXC13;;chr2:176969228..176969260,+!p1@HOXD11!0.92!7.24!HOXD11;;chr7:17338266..17338282,+!p1@AHR!0.91!80.78!AHR;;chr2:223163706..223163730,-!p1@PAX3!0.91!7.14!PAX3;;chr14:29236269..29236285,+!p3@FOXG1!0.91!7.04!FOXG1;;chr14:38064429..38064486,-!p1@FOXA1!0.91!7.04!FOXA1;;chr17:41277372..41277418,-!p1@BRCA1!0.90!26.62!BRCA1;;chr5:92918894..92918912,+!p2@NR2F1!0.90!23.56!NR2F1;;chr10:8096772..8096787,+!p2@GATA3!0.90!8.26!GATA3;;chr3:147111231..147111281,+!p3@ZIC1!0.88!6.63!ZIC1;;chr2:172967242..172967265,-!p2@DLX2!0.88!6.53!DLX2;;chr2:176969179..176969226,+!p2@HOXD11!0.88!6.53!HOXD11;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.87!30.80!TAL1;;chr6:126240380..126240430,+!p2@NCOA7!0.87!17.54!NCOA7;;chr6:45390002..45390023,+!p6@RUNX2!0.86!11.02!RUNX2;;chr15:80696703..80696754,+!p1@ARNT2!0.85!8.36!ARNT2;;chr8:72756213..72756243,-!p5@MSC!0.85!8.06!MSC;;chr10:8096631..8096660,+!p1@GATA3!0.85!7.55!GATA3;;chr5:92919068..92919082,+!p5@NR2F1!0.85!7.45!NR2F1;;chr19:56879653..56879743,+!p1@ZNF542!0.84!46.92!ZNF542;;chr20:48599506..48599526,+!p1@SNAI1!0.84!40.80!SNAI1;;chr6:45390077..45390105,+!p9@RUNX2!0.84!7.75!RUNX2;;chr6:10412576..10412599,-!p5@TFAP2A!0.84!5.92!TFAP2A;;chr20:39317868..39317884,-!p1@MAFB!0.83!72.93!MAFB;;chr12:54332652..54332671,+!p2@HOXC13!0.83!5.71!HOXC13;;chr5:142780189..142780223,-!p6@NR3C1!0.83!5.71!NR3C1;;chr6:45390300..45390335,+!p4@RUNX2!0.82!8.98!RUNX2;;chr5:92918956..92918969,+!p4@NR2F1!0.82!6.22!NR2F1;;chr19:13136130..13136165,+!p6@NFIX!0.81!7.34!NFIX;;chr5:3595961..3595975,+!p3@IRX1!0.81!5.51!IRX1;;chr6:28321909..28321965,-!p3@ZNF323!0.81!5.41!ZNF323;;chr14:37131058..37131139,+!p1@PAX9!0.81!5.41!PAX9;;chr12:54332687..54332701,+!p3@HOXC13!0.80!5.30!HOXC13;;chr2:172950227..172950249,+!p2@DLX1!0.80!5.30!DLX1;;chr17:70117153..70117174,+!p1@SOX9!0.79!57.53!SOX9;;chr3:71179699..71179744,-!p2@FOXP1!0.79!42.23!FOXP1;;chr5:92918768..92918783,+!p8@NR2F1!0.79!5.20!NR2F1;;chrX:66764343..66764362,+!p4@AR!0.79!5.10!AR;;chr17:48072574..48072597,-!p1@DLX3!0.78!5.00!DLX3;;chr3:25469815..25469866,+!p3@RARB!0.78!5.00!RARB;;chr2:172967621..172967637,-!p1@DLX2!0.77!14.08!DLX2;;chr7:19157043..19157088,-!p2@TWIST1!0.77!13.26!TWIST1;;chr6:10412477..10412490,-!p10@TFAP2A!0.77!4.90!TFAP2A;;chr8:49833978..49833996,-!p1@SNAI2!0.76!107.71!SNAI2;;chr15:76629123..76629151,+!p1@ISL2!0.76!5.41!ISL2;;chr1:25291475..25291511,-!p2@RUNX3!0.76!4.69!RUNX3;;chr4:8873545..8873583,-!p1@HMX1!0.76!4.69!HMX1;;chr7:17338324..17338341,+!p3@AHR!0.75!16.93!AHR;;chr6:45390269..45390298,+!p5@RUNX2!0.75!7.96!RUNX2;;chr6:126240442..126240459,+!p4@NCOA7!0.75!6.12!NCOA7;;chr3:147111198..147111225,+!p4@ZIC1!0.75!4.59!ZIC1;;chr5:133450365..133450444,+!p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| | |ffid_belonging_in_development=CL:0000133,CL:0000339,CL:0000221,UBERON:0002532,UBERON:0006601,UBERON:0006238,UBERON:0010316 | ||
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|fonse_cell_line=FF:0100255 | |fonse_cell_line=FF:0100255 | ||
|fonse_cell_line_closure=FF:0100255 | |fonse_cell_line_closure=FF:0100255 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/glioblastoma%2520cell%2520line%253aT98G.CNhs11272.10485-107A8.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/glioblastoma%2520cell%2520line%253aT98G.CNhs11272.10485-107A8.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/glioblastoma%2520cell%2520line%253aT98G.CNhs11272.10485-107A8.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/glioblastoma%2520cell%2520line%253aT98G.CNhs11272.10485-107A8.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/glioblastoma%2520cell%2520line%253aT98G.CNhs11272.10485-107A8.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10485-107A8 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101583 | |||
|is_obsolete= | |||
|library_id=CNhs11272 | |||
|library_id_phase_based=2:CNhs11272 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10485 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10485 | |||
|name=glioblastoma cell line:T98G | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11272,LSID758,release008,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0.0210904460458432,0,0,0,0,0.098794404082164,0.0421808920916863,-0.232652406114404,-0.282403560576942,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.111142118256741,0,0,0,0,0,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0.403115931799533,0,-0.174034800027363,0,0,0,0,0,0,0,0,-0.0031245750669912,0,0,0,0,0,0,0,-0.0548114691509189,0,0,0.0816307569244618,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0421808920916863,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0959764158692182,0.202554788411241,0,0.0806252010881579,0.0579706994125275,0.115941398825055,0.0505651044983018,-0.117386754755052,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.096373593922461,0.207362156303025,0,0,-0.10962131649322,-0.199941130427843,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,0.0505651044983018,0,0.115941398825055,0.0421808920916863,0,0,0,0,0,0.0806252010881579,0,0,0.119426508808776,0.040312600544079,0.37212063750212,-0.0275737436984173,0.040312600544079,0,0.168243479472945,0,0,0,0,0.0421808920916863,0,0.0421808920916863,0,0,-0.0859389748608784,0,-0.0504125515893149,0.040312600544079,0,0.0421808920916863,0,0,0.177396260110027,0,0.0090446308976604,0.0475971377476864,0,0.0421808920916863,0,0,0.0226862312137738,0,-0.0402542827055828,0.0962542158141414,0.198669591216596,0.000593567428882502,-0.04680465889238,0,0,0,-0.475849104482929,0.089908439968819,0,0,0.061522840295296,-0.0373559398650675,0,0,1.04374048877083,0,-0.404171076555318,-0.000901391988580004,0,0.129093854248304,0,0,0,0,0,0,0,0,0,0,0,-0.0574934668214365,0.184086999273668,0.04748241443676,0.0806252010881579,0.234007656260054,0,0.0479058849721646,0,0,-0.373286155956567,-0.0220968403638091,-0.142229159225626,0.0229376051339745,0,0.0243516399177329,-0.0210508582629348,0.258103328392723,-0.441279611699847,0.111710584797412,0.0928632510295708,0.0228413850485542,0.0149279229814491,0.020307900897504,0.0478894588620068,-0.131313927268871,0,-0.062035088154377,-0.26409598685594,0.0806252010881579,0,0.0806252010881579,0.0682518667435621,0,0,0.409480311956365,0.094103638641801,0.254346552217114,0.0623583228608836,-0.0451928429934925,0.091966817160787,-0.0395325284566706,-0.0908310688022544,0.0744989872090628,0.318963713701875,0.0540670032955008,0,0,0.018977739578531,0.355593334642455,0.00347013711516586,0,-0.0987332427708711,-0.0683442610773682,0.040312600544079,-0.0956614469273586,-0.140576670646755,0,0,-0.0542566151462313,0.0421808920916863,0,0.203928575074497,0,0,0.0776426083835626,0.0349965578488912,-0.152230360467387,0,-0.0691970297962465,0.011267070770744,-0.0221746294432378,0,0.0022621828560021,0.0329644866801646,-0.0458953115293935,-0.0237218985315728,0,-0.0354084794704193,-0.213793377939679,0.0872649459674495,0.362928684730795,0.62961083754812,-0.0515955184376508,0.0145760044290817,0.0959764158692182,0.420514409363076,0.0609666977868278,1.89580751626296,-0.0173924796037297,0.0783439626539676,-0.0602018213276794,-0.000778470653046259,0.0904540637993552,0.065265374218464,-0.0471448932810341,0,0.0850454668651834,0.00486434854824755,0.0196288957662679,-0.391833295737232,-0.11254800765304,0.239672912192904,0,-0.0893310423911796,-0.0910821099787952,0,0.0347024945307555,-0.00428029941719073,0,-0.00176662759863108,-0.0188195511745022,-0.211650427864589,0.137638787342967,0,-0.170783848095812,0,0,-0.158338308699573,0.0473689328150294,0,-0.0325728626402459,-0.0716410450573238,-0.183934861875892,-0.0737901813432478,0,0,0.253894688440414,0,0,-0.0948524678653938,0.137029641048098,-0.122582316896225,-0.0459641851837304,0,0.0388350820270513,0,0,-0.0289273102291674,0,0.169856649722125,0,0,0.176764205682343,0,0,0,0.0421808920916863,0.066994617304826,0.17631733931455,0,0,0,0,0,0,0.197941585502484,0.285244550376667,0,0.0722184896598603,0,0.0421808920916863,0,0,0,-0.0479592086121149,0,0,0.49897679338239,0,-0.0423922145882624,0,0,0.040312600544079,0,0.187392529246058,-0.0872951632696691,0.0421808920916863,0.0167377492383765,0.0421808920916863,0,0,0,-0.0861409897892114,0,0,0.0210904460458432,0.0210904460458432,-0.0155495649619777,-0.17796846880122,0,0,0,-0.27695440160179,0,0,0,0,-0.0931912438515557,0,0,0,0,-0.19934993996066,-0.0394009874551552,0,0.071741648017998,-0.0441250229897183,0.130020775685391,0,0.0806252010881579,0.263173483935293,0,0,0.0958597208855958,-0.0355547878465474,0.0421808920916863,0.0370459234664103,0,0,0,0,0.207362156303025,0.115941398825055,-0.214314512399756,0,0,0.0421808920916863,0,0,0,0,0,0,0.0210904460458432,0,-0.160030775324097,-0.0500431645668242,0.0151430123114607,0,0,0.0421808920916863,0,0,0,0.0549551223794674,0.114128216851347,0,0,0.0210904460458432,0,0,0,0,0,0.178681334318684,0,0,0,0.00391099105235053,0,-0.0548114691509189,0,0,0,0.0421808920916863,-0.564807121153884,0,0,0.0493792347341321,0,0,0,0,0,0,0.00040571998521493,0,0,0,0,0,0,0.0840430702675776,-0.415634192064504,0,0,0,0,0,0.0421808920916863,0,-0.232652406114404,0,0,0,0,-0.071703481617291,0,0,0,0.178048585790262,0,0.098794404082164,0,0,0,0,0,0,0.192622109520055,0,0,0,0,0,0,0.0806252010881579,0,0,0,0,0,0,0,0.512207590300526,0.0210904460458432,0.0421808920916863,0.0204801225655877,0,0,0.217169160583528,0,0,0,0,0,0,-0.010249977982684,0.0991964482056148,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.207362156303025,0,0,0,0,0,0,0.0423131506665978,0,0,0,0,0,0,0,-0.0979578962680575,0,0,-0.0306297632106041,0,0,0.0145722422538746,0,0,0,-0.184295762505197,-0.0516843972859133,0.0359784333807081,0,0,0,0.0492955056690577,0,0,0,0,-0.0245964953272151,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0806252010881579,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.111142118256741,0,0,0.0421808920916863,0,0,0,0,0,0,0,0.0210904460458432,0,0.103681078151513,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.282844970579418,0.0210904460458432,0,0,0,0,0,0,-0.0340113632754165,0.0806252010881579,0,0,0,0,0,0,0,0,0,0,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| |||
|rna_box=107 | |||
|rna_catalog_number= | |||
|rna_concentration=1.58593 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.07 | |||
|rna_od260/280=2.09 | |||
|rna_position=A8 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=107A8 | |||
|rna_weight_ug=39.64825 | |||
|sample_age=61 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB1954 | |||
|sample_cell_line=T98G | |||
|sample_cell_lot= | |||
|sample_cell_type=glioblast | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=glioblastoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.16848552028871e-270!GO:0043231;intracellular membrane-bound organelle;1.68951944434185e-227!GO:0043227;membrane-bound organelle;2.5184978362496e-227!GO:0043226;organelle;1.92734027576501e-223!GO:0043229;intracellular organelle;6.5883122853149e-223!GO:0005737;cytoplasm;1.43123567234051e-176!GO:0044422;organelle part;2.17415392971345e-161!GO:0044446;intracellular organelle part;8.86261890558894e-160!GO:0044444;cytoplasmic part;3.24566237314965e-124!GO:0032991;macromolecular complex;3.04863198661015e-116!GO:0005634;nucleus;2.90978742518845e-109!GO:0044237;cellular metabolic process;1.39267826639276e-107!GO:0044238;primary metabolic process;5.41514302113817e-106!GO:0043170;macromolecule metabolic process;3.70835599802112e-101!GO:0030529;ribonucleoprotein complex;1.44089556429782e-88!GO:0044428;nuclear part;8.37938658670088e-86!GO:0043233;organelle lumen;3.9042790166223e-85!GO:0031974;membrane-enclosed lumen;3.9042790166223e-85!GO:0003723;RNA binding;7.73454238230166e-75!GO:0005515;protein binding;5.22223171570452e-72!GO:0005739;mitochondrion;9.66175089690422e-70!GO:0043283;biopolymer metabolic process;2.04073310445452e-64!GO:0043234;protein complex;1.71368162647901e-62!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.2930409238178e-60!GO:0010467;gene expression;1.46220475779083e-56!GO:0016043;cellular component organization and biogenesis;1.00823187274823e-53!GO:0031981;nuclear lumen;4.55443871290676e-53!GO:0005840;ribosome;1.38498059746009e-51!GO:0006396;RNA processing;1.00749577476802e-50!GO:0031090;organelle membrane;2.91929709389926e-49!GO:0006412;translation;4.68414210672348e-49!GO:0019538;protein metabolic process;2.54696196873979e-48!GO:0044429;mitochondrial part;3.88605561067121e-48!GO:0003735;structural constituent of ribosome;2.02576558130666e-45!GO:0031967;organelle envelope;1.7137117544555e-43!GO:0031975;envelope;4.43145103667588e-43!GO:0044260;cellular macromolecule metabolic process;4.85706550685016e-42!GO:0033036;macromolecule localization;1.75445589644514e-41!GO:0044267;cellular protein metabolic process;2.02897524688108e-41!GO:0016071;mRNA metabolic process;2.18982015172993e-41!GO:0006259;DNA metabolic process;7.85843262959211e-41!GO:0003676;nucleic acid binding;1.03157408399425e-39!GO:0015031;protein transport;1.4913514447114e-39!GO:0033279;ribosomal subunit;2.92937875974401e-39!GO:0005829;cytosol;1.81599109115439e-38!GO:0006996;organelle organization and biogenesis;1.00547302903035e-37!GO:0044249;cellular biosynthetic process;1.23969798812623e-37!GO:0008380;RNA splicing;1.4593116471476e-37!GO:0008104;protein localization;1.49214981356373e-37!GO:0045184;establishment of protein localization;3.81739548198707e-37!GO:0006397;mRNA processing;3.81739548198707e-37!GO:0009058;biosynthetic process;7.95509973737097e-37!GO:0007049;cell cycle;1.69494641722666e-36!GO:0009059;macromolecule biosynthetic process;5.49106457105935e-36!GO:0046907;intracellular transport;1.01270847318628e-35!GO:0005654;nucleoplasm;1.65497031137904e-35!GO:0043228;non-membrane-bound organelle;2.31127230459177e-35!GO:0043232;intracellular non-membrane-bound organelle;2.31127230459177e-35!GO:0065003;macromolecular complex assembly;2.05324582348622e-34!GO:0005740;mitochondrial envelope;2.04244485313732e-30!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.97914860970642e-30!GO:0022607;cellular component assembly;6.71836752785625e-30!GO:0016070;RNA metabolic process;1.17170361485482e-29!GO:0044451;nucleoplasm part;1.52179282068491e-29!GO:0019866;organelle inner membrane;9.49517529749677e-29!GO:0031966;mitochondrial membrane;1.05126726773877e-28!GO:0006886;intracellular protein transport;5.31954563793132e-28!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.04819970764141e-27!GO:0005681;spliceosome;4.67136445664977e-27!GO:0006974;response to DNA damage stimulus;1.9283092632746e-26!GO:0005743;mitochondrial inner membrane;2.18156517244827e-26!GO:0022402;cell cycle process;2.37207529845849e-26!GO:0000278;mitotic cell cycle;8.10788410860466e-26!GO:0000166;nucleotide binding;7.33199281008552e-25!GO:0051649;establishment of cellular localization;5.41538114799395e-24!GO:0051641;cellular localization;9.75498533047613e-24!GO:0044445;cytosolic part;2.69360293279552e-23!GO:0016462;pyrophosphatase activity;4.59935506233082e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;6.95833563359421e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;1.05881376043061e-22!GO:0006281;DNA repair;1.17897125292763e-22!GO:0017111;nucleoside-triphosphatase activity;1.21005892950792e-22!GO:0005694;chromosome;4.8258954801748e-22!GO:0000087;M phase of mitotic cell cycle;5.84260907292814e-22!GO:0006119;oxidative phosphorylation;8.33125454041298e-22!GO:0007067;mitosis;1.57462442975831e-21!GO:0015935;small ribosomal subunit;2.22833080728608e-21!GO:0031980;mitochondrial lumen;2.39983957861172e-21!GO:0005759;mitochondrial matrix;2.39983957861172e-21!GO:0051301;cell division;3.57060827242173e-21!GO:0044427;chromosomal part;4.99530198922755e-20!GO:0016874;ligase activity;5.39796143851555e-20!GO:0044455;mitochondrial membrane part;1.24207749276391e-19!GO:0006260;DNA replication;2.18556855222833e-19!GO:0008134;transcription factor binding;2.22040498151958e-19!GO:0022403;cell cycle phase;2.28910879138968e-19!GO:0009719;response to endogenous stimulus;4.1622981548746e-19!GO:0015934;large ribosomal subunit;4.77783736862272e-19!GO:0012505;endomembrane system;5.08307561625649e-19!GO:0006457;protein folding;6.73490655960384e-19!GO:0006512;ubiquitin cycle;9.7159109682252e-19!GO:0022618;protein-RNA complex assembly;1.90445907869017e-18!GO:0032553;ribonucleotide binding;7.30957416833354e-18!GO:0032555;purine ribonucleotide binding;7.30957416833354e-18!GO:0044265;cellular macromolecule catabolic process;1.03456007790165e-17!GO:0005730;nucleolus;1.14506833822977e-17!GO:0000279;M phase;1.1514203096803e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.59627441014861e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;2.27632700029695e-17!GO:0017076;purine nucleotide binding;2.64916940853083e-17!GO:0019941;modification-dependent protein catabolic process;4.00233998794518e-17!GO:0043632;modification-dependent macromolecule catabolic process;4.00233998794518e-17!GO:0005783;endoplasmic reticulum;4.05680153049568e-17!GO:0043285;biopolymer catabolic process;5.01230343208364e-17!GO:0051186;cofactor metabolic process;5.82239553214291e-17!GO:0006511;ubiquitin-dependent protein catabolic process;5.87491238130696e-17!GO:0044257;cellular protein catabolic process;6.80191591889397e-17!GO:0048770;pigment granule;9.56397382775141e-17!GO:0042470;melanosome;9.56397382775141e-17!GO:0005746;mitochondrial respiratory chain;2.06407393917313e-16!GO:0005761;mitochondrial ribosome;4.32227401542546e-16!GO:0000313;organellar ribosome;4.32227401542546e-16!GO:0051276;chromosome organization and biogenesis;4.36967344953557e-16!GO:0009057;macromolecule catabolic process;1.05058974182378e-15!GO:0008135;translation factor activity, nucleic acid binding;1.06881611864261e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.30290690185157e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.45342535682857e-15!GO:0044432;endoplasmic reticulum part;4.95344101247165e-15!GO:0005524;ATP binding;5.08455615611111e-15!GO:0050794;regulation of cellular process;6.93830929416904e-15!GO:0030163;protein catabolic process;8.2328492604278e-15!GO:0006366;transcription from RNA polymerase II promoter;8.2328492604278e-15!GO:0032559;adenyl ribonucleotide binding;1.00131722820536e-14!GO:0044248;cellular catabolic process;1.20306932487412e-14!GO:0048193;Golgi vesicle transport;1.6166335354376e-14!GO:0006605;protein targeting;1.618639007236e-14!GO:0050136;NADH dehydrogenase (quinone) activity;2.07698814569358e-14!GO:0003954;NADH dehydrogenase activity;2.07698814569358e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.07698814569358e-14!GO:0030554;adenyl nucleotide binding;4.98129782988974e-14!GO:0042623;ATPase activity, coupled;7.63441938254854e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;8.14906564316449e-14!GO:0000375;RNA splicing, via transesterification reactions;8.14906564316449e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.14906564316449e-14!GO:0005635;nuclear envelope;8.98979116237767e-14!GO:0051082;unfolded protein binding;9.24126719905068e-14!GO:0003712;transcription cofactor activity;1.39014150855852e-13!GO:0016887;ATPase activity;1.79019417379517e-13!GO:0051726;regulation of cell cycle;2.24637132571954e-13!GO:0000074;regulation of progression through cell cycle;2.49400797639255e-13!GO:0006732;coenzyme metabolic process;2.67492727264197e-13!GO:0043412;biopolymer modification;4.51081110047328e-13!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.82384676003726e-13!GO:0042775;organelle ATP synthesis coupled electron transport;7.87917537058628e-13!GO:0042773;ATP synthesis coupled electron transport;7.87917537058628e-13!GO:0044453;nuclear membrane part;8.18112878204551e-13!GO:0042254;ribosome biogenesis and assembly;8.9918747861316e-13!GO:0031965;nuclear membrane;9.92476441461781e-13!GO:0016604;nuclear body;1.26933683069134e-12!GO:0030964;NADH dehydrogenase complex (quinone);2.21972268529027e-12!GO:0045271;respiratory chain complex I;2.21972268529027e-12!GO:0005747;mitochondrial respiratory chain complex I;2.21972268529027e-12!GO:0003743;translation initiation factor activity;3.25758950385241e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;5.32880913744054e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.62051275810929e-12!GO:0006325;establishment and/or maintenance of chromatin architecture;6.43816256584723e-12!GO:0015630;microtubule cytoskeleton;7.786094193929e-12!GO:0005794;Golgi apparatus;1.28031764963818e-11!GO:0006323;DNA packaging;2.12534551952331e-11!GO:0006413;translational initiation;2.13824342312087e-11!GO:0006464;protein modification process;3.46881106034475e-11!GO:0004386;helicase activity;4.99773330112057e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;6.01495455971103e-11!GO:0012501;programmed cell death;6.522959152395e-11!GO:0009259;ribonucleotide metabolic process;6.58889749108805e-11!GO:0000775;chromosome, pericentric region;7.14542289510626e-11!GO:0016192;vesicle-mediated transport;9.59159679272313e-11!GO:0006461;protein complex assembly;1.10865208056432e-10!GO:0006915;apoptosis;1.14672100361252e-10!GO:0006913;nucleocytoplasmic transport;1.17268150245769e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.35085883789017e-10!GO:0006163;purine nucleotide metabolic process;1.61953369361896e-10!GO:0005789;endoplasmic reticulum membrane;1.62884413948019e-10!GO:0008639;small protein conjugating enzyme activity;1.90445225529889e-10!GO:0006399;tRNA metabolic process;2.61041842259054e-10!GO:0051169;nuclear transport;2.71619781179869e-10!GO:0005667;transcription factor complex;3.26912577736603e-10!GO:0005643;nuclear pore;3.29790935769126e-10!GO:0065002;intracellular protein transport across a membrane;3.51088909776304e-10!GO:0019222;regulation of metabolic process;3.78143631500217e-10!GO:0004842;ubiquitin-protein ligase activity;4.37922707287353e-10!GO:0006446;regulation of translational initiation;4.57460756103828e-10!GO:0008219;cell death;5.04615140451805e-10!GO:0016265;death;5.04615140451805e-10!GO:0043566;structure-specific DNA binding;6.05650556135742e-10!GO:0043687;post-translational protein modification;6.63872910269487e-10!GO:0006164;purine nucleotide biosynthetic process;7.13381716844136e-10!GO:0009150;purine ribonucleotide metabolic process;7.30971510207223e-10!GO:0050789;regulation of biological process;7.65762446318463e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;7.95497300596713e-10!GO:0016607;nuclear speck;8.25512307806919e-10!GO:0019787;small conjugating protein ligase activity;8.25512307806919e-10!GO:0009260;ribonucleotide biosynthetic process;9.83077683541173e-10!GO:0006403;RNA localization;1.42997342566947e-09!GO:0003697;single-stranded DNA binding;1.50710677508433e-09!GO:0005793;ER-Golgi intermediate compartment;1.66522446973219e-09!GO:0008026;ATP-dependent helicase activity;1.69962124776226e-09!GO:0050657;nucleic acid transport;1.71730001706239e-09!GO:0051236;establishment of RNA localization;1.71730001706239e-09!GO:0050658;RNA transport;1.71730001706239e-09!GO:0000785;chromatin;2.26923127580393e-09!GO:0009055;electron carrier activity;2.6658392840223e-09!GO:0008565;protein transporter activity;2.66613769966487e-09!GO:0048523;negative regulation of cellular process;2.69434031486565e-09!GO:0016881;acid-amino acid ligase activity;3.00618281530993e-09!GO:0009152;purine ribonucleotide biosynthetic process;3.1790830104782e-09!GO:0065004;protein-DNA complex assembly;3.32371598252852e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.46484286081758e-09!GO:0004812;aminoacyl-tRNA ligase activity;3.46484286081758e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.46484286081758e-09!GO:0005819;spindle;4.02042118845647e-09!GO:0009060;aerobic respiration;4.88214897738504e-09!GO:0043038;amino acid activation;4.91620200535064e-09!GO:0006418;tRNA aminoacylation for protein translation;4.91620200535064e-09!GO:0043039;tRNA aminoacylation;4.91620200535064e-09!GO:0006261;DNA-dependent DNA replication;5.32521683964747e-09!GO:0045333;cellular respiration;7.31976279014384e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;7.31976279014384e-09!GO:0006333;chromatin assembly or disassembly;1.28687027897178e-08!GO:0016568;chromatin modification;1.32659054669395e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.4727258766224e-08!GO:0009141;nucleoside triphosphate metabolic process;1.78505801270081e-08!GO:0006364;rRNA processing;1.92045372945168e-08!GO:0006888;ER to Golgi vesicle-mediated transport;2.0993824176661e-08!GO:0046930;pore complex;2.12413537514006e-08!GO:0017038;protein import;2.31199049146509e-08!GO:0009056;catabolic process;2.55468709645946e-08!GO:0051188;cofactor biosynthetic process;2.66848431968406e-08!GO:0015986;ATP synthesis coupled proton transport;2.69438232565419e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.69438232565419e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.02146641525709e-08!GO:0009144;purine nucleoside triphosphate metabolic process;3.02146641525709e-08!GO:0005839;proteasome core complex (sensu Eukaryota);3.24576263774693e-08!GO:0006099;tricarboxylic acid cycle;3.4224900629305e-08!GO:0046356;acetyl-CoA catabolic process;3.4224900629305e-08!GO:0007005;mitochondrion organization and biogenesis;4.49607019325678e-08!GO:0016072;rRNA metabolic process;4.89475581109762e-08!GO:0016779;nucleotidyltransferase activity;5.02140496023058e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;6.16408271750783e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;6.46709910679008e-08!GO:0031323;regulation of cellular metabolic process;6.87970146719041e-08!GO:0006084;acetyl-CoA metabolic process;8.26924084402028e-08!GO:0009142;nucleoside triphosphate biosynthetic process;8.74592510905612e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;8.74592510905612e-08!GO:0046034;ATP metabolic process;9.74049535561794e-08!GO:0031324;negative regulation of cellular metabolic process;1.08397261394546e-07!GO:0032446;protein modification by small protein conjugation;1.11144526951077e-07!GO:0003924;GTPase activity;1.13326874628449e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.31556497526299e-07!GO:0005657;replication fork;1.35220332994949e-07!GO:0005813;centrosome;1.42468786305789e-07!GO:0048519;negative regulation of biological process;1.43714352090399e-07!GO:0051028;mRNA transport;1.56896133445226e-07!GO:0007051;spindle organization and biogenesis;1.67969440875793e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.67969440875793e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.83268647946421e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.83268647946421e-07!GO:0005815;microtubule organizing center;2.04947160566925e-07!GO:0016567;protein ubiquitination;2.07644562474664e-07!GO:0004298;threonine endopeptidase activity;2.18078923796611e-07!GO:0016564;transcription repressor activity;2.21706097003554e-07!GO:0030120;vesicle coat;2.28555596970033e-07!GO:0030662;coated vesicle membrane;2.28555596970033e-07!GO:0000075;cell cycle checkpoint;2.28555596970033e-07!GO:0048475;coated membrane;2.84366136801897e-07!GO:0030117;membrane coat;2.84366136801897e-07!GO:0015078;hydrogen ion transmembrane transporter activity;3.43607731978179e-07!GO:0019829;cation-transporting ATPase activity;3.75111185051702e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.28146008824335e-07!GO:0006350;transcription;4.59151916552769e-07!GO:0016563;transcription activator activity;4.74871238435914e-07!GO:0006754;ATP biosynthetic process;4.84338329224307e-07!GO:0006753;nucleoside phosphate metabolic process;4.84338329224307e-07!GO:0000151;ubiquitin ligase complex;5.38953113417145e-07!GO:0051187;cofactor catabolic process;5.46528639014731e-07!GO:0043623;cellular protein complex assembly;5.6211212755982e-07!GO:0003714;transcription corepressor activity;7.20327932285381e-07!GO:0000245;spliceosome assembly;7.55402726841818e-07!GO:0009109;coenzyme catabolic process;7.77427634114644e-07!GO:0005788;endoplasmic reticulum lumen;8.42303511171897e-07!GO:0030532;small nuclear ribonucleoprotein complex;8.69344536754156e-07!GO:0009892;negative regulation of metabolic process;1.05296531827266e-06!GO:0043067;regulation of programmed cell death;1.26051650928499e-06!GO:0042981;regulation of apoptosis;1.52285212614819e-06!GO:0009117;nucleotide metabolic process;1.62797414990623e-06!GO:0045786;negative regulation of progression through cell cycle;1.75819268964193e-06!GO:0051246;regulation of protein metabolic process;1.81459224285853e-06!GO:0009108;coenzyme biosynthetic process;1.93524873205854e-06!GO:0005798;Golgi-associated vesicle;1.98088967852266e-06!GO:0051329;interphase of mitotic cell cycle;2.00380897232831e-06!GO:0016491;oxidoreductase activity;2.29220868933835e-06!GO:0003713;transcription coactivator activity;3.00466979296625e-06!GO:0005768;endosome;3.0524065540456e-06!GO:0045259;proton-transporting ATP synthase complex;3.10800849631121e-06!GO:0006752;group transfer coenzyme metabolic process;3.34279591756462e-06!GO:0008094;DNA-dependent ATPase activity;3.47894496549221e-06!GO:0006302;double-strand break repair;3.58982362402083e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;3.79515330321717e-06!GO:0016787;hydrolase activity;3.81052230704494e-06!GO:0016469;proton-transporting two-sector ATPase complex;3.99390828486966e-06!GO:0006613;cotranslational protein targeting to membrane;4.43831206432598e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;5.13134754643276e-06!GO:0016481;negative regulation of transcription;5.54758757020804e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.6378304595451e-06!GO:0003899;DNA-directed RNA polymerase activity;5.66090582664484e-06!GO:0016740;transferase activity;6.44137801327871e-06!GO:0010468;regulation of gene expression;6.51465055071379e-06!GO:0051325;interphase;7.07877392230555e-06!GO:0043069;negative regulation of programmed cell death;7.2371860107394e-06!GO:0000776;kinetochore;7.8787676296214e-06!GO:0051427;hormone receptor binding;9.23954956968811e-06!GO:0051168;nuclear export;9.47320484361661e-06!GO:0065007;biological regulation;1.02937739465125e-05!GO:0006334;nucleosome assembly;1.12169509203521e-05!GO:0003690;double-stranded DNA binding;1.1480965065041e-05!GO:0003682;chromatin binding;1.21479549248445e-05!GO:0005762;mitochondrial large ribosomal subunit;1.28175097070602e-05!GO:0000315;organellar large ribosomal subunit;1.28175097070602e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.38722491097145e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;1.41552436077095e-05!GO:0003724;RNA helicase activity;1.45155600922948e-05!GO:0044440;endosomal part;1.52260084478873e-05!GO:0010008;endosome membrane;1.52260084478873e-05!GO:0043066;negative regulation of apoptosis;1.5537350346696e-05!GO:0006310;DNA recombination;1.55634750138555e-05!GO:0031497;chromatin assembly;1.79078150476033e-05!GO:0008654;phospholipid biosynthetic process;1.80233488798243e-05!GO:0035257;nuclear hormone receptor binding;2.03932976423376e-05!GO:0016859;cis-trans isomerase activity;2.0984542463991e-05!GO:0032774;RNA biosynthetic process;2.20172919909876e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.22511389615347e-05!GO:0005770;late endosome;2.29028468092602e-05!GO:0006606;protein import into nucleus;2.48904217944808e-05!GO:0005773;vacuole;2.52416377981861e-05!GO:0005525;GTP binding;2.69328842508723e-05!GO:0006793;phosphorus metabolic process;2.84797216417174e-05!GO:0006796;phosphate metabolic process;2.84797216417174e-05!GO:0005874;microtubule;3.06263664394947e-05!GO:0007010;cytoskeleton organization and biogenesis;3.07087902598912e-05!GO:0006351;transcription, DNA-dependent;3.11049719978825e-05!GO:0030867;rough endoplasmic reticulum membrane;3.4543430815371e-05!GO:0000314;organellar small ribosomal subunit;3.65268708093481e-05!GO:0005763;mitochondrial small ribosomal subunit;3.65268708093481e-05!GO:0051052;regulation of DNA metabolic process;4.00039473536489e-05!GO:0051170;nuclear import;4.16465275226725e-05!GO:0045454;cell redox homeostasis;4.45473157177013e-05!GO:0007059;chromosome segregation;4.83729528892796e-05!GO:0044431;Golgi apparatus part;4.84856927567911e-05!GO:0043021;ribonucleoprotein binding;4.954239810721e-05!GO:0007017;microtubule-based process;5.15956275137171e-05!GO:0048522;positive regulation of cellular process;5.43563892231949e-05!GO:0016853;isomerase activity;5.59434578531391e-05!GO:0006612;protein targeting to membrane;6.28417566856916e-05!GO:0007088;regulation of mitosis;6.56913923197936e-05!GO:0007093;mitotic cell cycle checkpoint;7.71231417829433e-05!GO:0031968;organelle outer membrane;7.91927214636785e-05!GO:0003684;damaged DNA binding;9.99638814506309e-05!GO:0016310;phosphorylation;0.000100464445265972!GO:0006916;anti-apoptosis;0.000100657345810563!GO:0019867;outer membrane;0.00010807228851353!GO:0046474;glycerophospholipid biosynthetic process;0.00011274278798717!GO:0006414;translational elongation;0.000115516908639452!GO:0015980;energy derivation by oxidation of organic compounds;0.000116783681776387!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000116783681776387!GO:0016363;nuclear matrix;0.000118664573053727!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000118664573053727!GO:0006091;generation of precursor metabolites and energy;0.000130396169674947!GO:0003729;mRNA binding;0.000131467478038504!GO:0003677;DNA binding;0.000149450407736687!GO:0019843;rRNA binding;0.000153879802478246!GO:0046983;protein dimerization activity;0.000154781725301455!GO:0031982;vesicle;0.000163147366776729!GO:0045449;regulation of transcription;0.000175111779265697!GO:0033116;ER-Golgi intermediate compartment membrane;0.00017689009405918!GO:0016023;cytoplasmic membrane-bound vesicle;0.000177001365431918!GO:0046483;heterocycle metabolic process;0.000180396718003137!GO:0031988;membrane-bound vesicle;0.000180725226342635!GO:0003702;RNA polymerase II transcription factor activity;0.000183382977070397!GO:0000323;lytic vacuole;0.000183683782357533!GO:0005764;lysosome;0.000183683782357533!GO:0031410;cytoplasmic vesicle;0.000196499913428545!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000209416625069815!GO:0046489;phosphoinositide biosynthetic process;0.000223382901316822!GO:0032561;guanyl ribonucleotide binding;0.000227097980829795!GO:0019001;guanyl nucleotide binding;0.000227097980829795!GO:0008361;regulation of cell size;0.000228219226062068!GO:0006839;mitochondrial transport;0.000230371272019768!GO:0043681;protein import into mitochondrion;0.00025866697118367!GO:0005741;mitochondrial outer membrane;0.000269089860688371!GO:0006352;transcription initiation;0.000274231878354295!GO:0008186;RNA-dependent ATPase activity;0.000302647933876579!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000307914194554759!GO:0015399;primary active transmembrane transporter activity;0.000307914194554759!GO:0007052;mitotic spindle organization and biogenesis;0.000320682657751694!GO:0006626;protein targeting to mitochondrion;0.000329899207298972!GO:0031252;leading edge;0.000338487320060501!GO:0016049;cell growth;0.000377725522314971!GO:0005048;signal sequence binding;0.000398326493890288!GO:0045893;positive regulation of transcription, DNA-dependent;0.000408221827079035!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.000448985600472137!GO:0003678;DNA helicase activity;0.000451407284705012!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000475215034463542!GO:0015631;tubulin binding;0.000480360680982583!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00051029699476731!GO:0051789;response to protein stimulus;0.000516936828239413!GO:0006986;response to unfolded protein;0.000516936828239413!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000526759838109851!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000526759838109851!GO:0008250;oligosaccharyl transferase complex;0.000538638528316156!GO:0006520;amino acid metabolic process;0.000538638528316156!GO:0030521;androgen receptor signaling pathway;0.000553826849176366!GO:0030663;COPI coated vesicle membrane;0.000570571196186062!GO:0030126;COPI vesicle coat;0.000570571196186062!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000589517629894785!GO:0030137;COPI-coated vesicle;0.000691722003138196!GO:0016251;general RNA polymerase II transcription factor activity;0.000728594167470221!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.000730533866140381!GO:0045941;positive regulation of transcription;0.000775647957212831!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000784548468019462!GO:0030133;transport vesicle;0.000810864807093776!GO:0006383;transcription from RNA polymerase III promoter;0.000856943740476765!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000860406158253623!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000860406158253623!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000860406158253623!GO:0004004;ATP-dependent RNA helicase activity;0.000891193029712576!GO:0000096;sulfur amino acid metabolic process;0.00092839490557192!GO:0005885;Arp2/3 protein complex;0.00093242362207757!GO:0004576;oligosaccharyl transferase activity;0.000946114674605802!GO:0005769;early endosome;0.000946909348519366!GO:0006950;response to stress;0.000947932557081488!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00101898044872479!GO:0019752;carboxylic acid metabolic process;0.00103100727919421!GO:0005876;spindle microtubule;0.00103689190692243!GO:0051252;regulation of RNA metabolic process;0.00110247827169241!GO:0000139;Golgi membrane;0.00111068891942042!GO:0006355;regulation of transcription, DNA-dependent;0.00112315198325252!GO:0006082;organic acid metabolic process;0.00113959130733288!GO:0007006;mitochondrial membrane organization and biogenesis;0.00118168066477325!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00119144729898549!GO:0043596;nuclear replication fork;0.00121628200161658!GO:0000059;protein import into nucleus, docking;0.00121632020108405!GO:0032508;DNA duplex unwinding;0.00128105608511995!GO:0032392;DNA geometric change;0.00128105608511995!GO:0045892;negative regulation of transcription, DNA-dependent;0.00129382694411071!GO:0051920;peroxiredoxin activity;0.00132163954305646!GO:0035258;steroid hormone receptor binding;0.00132513751107714!GO:0043284;biopolymer biosynthetic process;0.00133956324227529!GO:0009165;nucleotide biosynthetic process;0.00134916117823147!GO:0008168;methyltransferase activity;0.00142365066373104!GO:0006402;mRNA catabolic process;0.00142380724156654!GO:0001558;regulation of cell growth;0.0015032949125132!GO:0030880;RNA polymerase complex;0.00150728739370295!GO:0016044;membrane organization and biogenesis;0.00151872339742182!GO:0019899;enzyme binding;0.00161625416383286!GO:0016741;transferase activity, transferring one-carbon groups;0.00161625416383286!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00163126854407223!GO:0042802;identical protein binding;0.00165993821483728!GO:0048500;signal recognition particle;0.00169189659440221!GO:0006891;intra-Golgi vesicle-mediated transport;0.00174225099789661!GO:0000910;cytokinesis;0.00175459656495468!GO:0006268;DNA unwinding during replication;0.00186554780823862!GO:0031124;mRNA 3'-end processing;0.00186554780823862!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00192880090449154!GO:0004527;exonuclease activity;0.0019888790859977!GO:0006650;glycerophospholipid metabolic process;0.00203751311688898!GO:0005637;nuclear inner membrane;0.00211045376403876!GO:0006284;base-excision repair;0.00219386287508295!GO:0005684;U2-dependent spliceosome;0.00220150724914835!GO:0008047;enzyme activator activity;0.00222863331619307!GO:0006611;protein export from nucleus;0.00235745316226923!GO:0006506;GPI anchor biosynthetic process;0.00238279307074919!GO:0048471;perinuclear region of cytoplasm;0.00255349281793756!GO:0005905;coated pit;0.00266112836037298!GO:0051087;chaperone binding;0.00287333811731289!GO:0043624;cellular protein complex disassembly;0.00292122045450955!GO:0030176;integral to endoplasmic reticulum membrane;0.00293163995980604!GO:0008022;protein C-terminus binding;0.00297248880799871!GO:0044452;nucleolar part;0.00298541598072821!GO:0006405;RNA export from nucleus;0.00300008827323923!GO:0065009;regulation of a molecular function;0.0030030155354742!GO:0006497;protein amino acid lipidation;0.003018362745833!GO:0008033;tRNA processing;0.00302225988611334!GO:0043492;ATPase activity, coupled to movement of substances;0.00304927804581045!GO:0008312;7S RNA binding;0.00312885983750914!GO:0018196;peptidyl-asparagine modification;0.00322487912150265!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00322487912150265!GO:0008180;signalosome;0.0032286781532244!GO:0000725;recombinational repair;0.0032286781532244!GO:0000724;double-strand break repair via homologous recombination;0.0032286781532244!GO:0006275;regulation of DNA replication;0.0032654347353429!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0032654347353429!GO:0000428;DNA-directed RNA polymerase complex;0.0032654347353429!GO:0000922;spindle pole;0.0032935076156055!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00344027255555271!GO:0030518;steroid hormone receptor signaling pathway;0.0034626750850977!GO:0006505;GPI anchor metabolic process;0.00349962614625465!GO:0030134;ER to Golgi transport vesicle;0.00368949445537338!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00376257782503772!GO:0045047;protein targeting to ER;0.00376257782503772!GO:0030384;phosphoinositide metabolic process;0.00377465706699458!GO:0051539;4 iron, 4 sulfur cluster binding;0.00379747425293174!GO:0030132;clathrin coat of coated pit;0.00388073241533049!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00389832174706976!GO:0015002;heme-copper terminal oxidase activity;0.00389832174706976!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00389832174706976!GO:0004129;cytochrome-c oxidase activity;0.00389832174706976!GO:0007243;protein kinase cascade;0.00415690389875544!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00419765609887209!GO:0000082;G1/S transition of mitotic cell cycle;0.00456182683906046!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0045903086275448!GO:0005791;rough endoplasmic reticulum;0.00460531250669952!GO:0050681;androgen receptor binding;0.00465150783134627!GO:0000049;tRNA binding;0.00465150783134627!GO:0046467;membrane lipid biosynthetic process;0.00474518642442654!GO:0050662;coenzyme binding;0.00477388348437818!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00480780418998156!GO:0043601;nuclear replisome;0.00487419509671332!GO:0030894;replisome;0.00487419509671332!GO:0000070;mitotic sister chromatid segregation;0.00517350315305477!GO:0006401;RNA catabolic process;0.00517539754857245!GO:0030658;transport vesicle membrane;0.00525333903317611!GO:0030127;COPII vesicle coat;0.00525333903317611!GO:0012507;ER to Golgi transport vesicle membrane;0.00525333903317611!GO:0006144;purine base metabolic process;0.00526600725711107!GO:0009116;nucleoside metabolic process;0.00535598779097878!GO:0006818;hydrogen transport;0.00542190708155274!GO:0000819;sister chromatid segregation;0.00544539928321817!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00553448544677785!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00553448544677785!GO:0031902;late endosome membrane;0.00572044841003135!GO:0048518;positive regulation of biological process;0.00576072934501897!GO:0042393;histone binding;0.00576283102939853!GO:0031072;heat shock protein binding;0.00576332800762506!GO:0031570;DNA integrity checkpoint;0.00577644160866892!GO:0008139;nuclear localization sequence binding;0.00584346277982707!GO:0032984;macromolecular complex disassembly;0.00594289634123157!GO:0015992;proton transport;0.00601475498273328!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.00616018842785753!GO:0006338;chromatin remodeling;0.00631822560108604!GO:0048487;beta-tubulin binding;0.00635642951776657!GO:0003746;translation elongation factor activity;0.00649254606042627!GO:0000287;magnesium ion binding;0.0065550750954012!GO:0000786;nucleosome;0.00678200029964715!GO:0006289;nucleotide-excision repair;0.00680781682249795!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.00695188243274797!GO:0006378;mRNA polyadenylation;0.00696448445104921!GO:0000152;nuclear ubiquitin ligase complex;0.00710258441165448!GO:0030118;clathrin coat;0.00724946147972779!GO:0006519;amino acid and derivative metabolic process;0.00730307615043389!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00739024580262302!GO:0042770;DNA damage response, signal transduction;0.00753185961552572!GO:0006740;NADPH regeneration;0.0075559975350552!GO:0006098;pentose-phosphate shunt;0.0075559975350552!GO:0003711;transcription elongation regulator activity;0.00764060816448105!GO:0009112;nucleobase metabolic process;0.00786704531054496!GO:0016584;nucleosome positioning;0.00786704531054496!GO:0009967;positive regulation of signal transduction;0.00793323718267774!GO:0043022;ribosome binding;0.00812698906312175!GO:0043488;regulation of mRNA stability;0.00812698906312175!GO:0043487;regulation of RNA stability;0.00812698906312175!GO:0007050;cell cycle arrest;0.00848450527035081!GO:0006749;glutathione metabolic process;0.00856218681413708!GO:0030036;actin cytoskeleton organization and biogenesis;0.00896795152515711!GO:0006270;DNA replication initiation;0.00907920488969613!GO:0043241;protein complex disassembly;0.00907920488969613!GO:0032200;telomere organization and biogenesis;0.0092656716590962!GO:0000723;telomere maintenance;0.0092656716590962!GO:0031123;RNA 3'-end processing;0.00936079548813943!GO:0016197;endosome transport;0.00979517758518458!GO:0016272;prefoldin complex;0.00995378708472635!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00995378708472635!GO:0042158;lipoprotein biosynthetic process;0.0100284041378752!GO:0017166;vinculin binding;0.0102093791731222!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0105375064628624!GO:0030660;Golgi-associated vesicle membrane;0.0106769875062722!GO:0005758;mitochondrial intermembrane space;0.010690131013136!GO:0044262;cellular carbohydrate metabolic process;0.0112211840036799!GO:0006778;porphyrin metabolic process;0.0112637309654145!GO:0033013;tetrapyrrole metabolic process;0.0112637309654145!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0114848287040137!GO:0051128;regulation of cellular component organization and biogenesis;0.0115455206411231!GO:0008632;apoptotic program;0.0116815151777777!GO:0005774;vacuolar membrane;0.0120746878391343!GO:0022411;cellular component disassembly;0.0121707317098347!GO:0008017;microtubule binding;0.0124016690748879!GO:0043189;H4/H2A histone acetyltransferase complex;0.0126267625690747!GO:0004518;nuclease activity;0.0130085075770552!GO:0000339;RNA cap binding;0.0130490333434747!GO:0022890;inorganic cation transmembrane transporter activity;0.0131243471512209!GO:0005669;transcription factor TFIID complex;0.0131243471512209!GO:0030522;intracellular receptor-mediated signaling pathway;0.0131243471512209!GO:0005862;muscle thin filament tropomyosin;0.0132095746147031!GO:0016408;C-acyltransferase activity;0.0133594224695216!GO:0005832;chaperonin-containing T-complex;0.0134128077017385!GO:0006595;polyamine metabolic process;0.0134403448663104!GO:0006376;mRNA splice site selection;0.0136824514135416!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0136824514135416!GO:0030659;cytoplasmic vesicle membrane;0.0137445743921636!GO:0006892;post-Golgi vesicle-mediated transport;0.0138473057416763!GO:0031577;spindle checkpoint;0.0139749043968581!GO:0004003;ATP-dependent DNA helicase activity;0.0139975771580461!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0141586155484577!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0143327245436395!GO:0046982;protein heterodimerization activity;0.0145691166562418!GO:0051287;NAD binding;0.0149439443916475!GO:0042168;heme metabolic process;0.0149803371599377!GO:0048037;cofactor binding;0.0151457740324615!GO:0008234;cysteine-type peptidase activity;0.0153046186048871!GO:0007034;vacuolar transport;0.0153851284533757!GO:0008652;amino acid biosynthetic process;0.0156158559383324!GO:0004674;protein serine/threonine kinase activity;0.0156740128960537!GO:0000726;non-recombinational repair;0.0161022262841299!GO:0006007;glucose catabolic process;0.0161987660431259!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0164417991556125!GO:0031625;ubiquitin protein ligase binding;0.0164424380369348!GO:0003923;GPI-anchor transamidase activity;0.0165319929493397!GO:0016255;attachment of GPI anchor to protein;0.0165319929493397!GO:0042765;GPI-anchor transamidase complex;0.0165319929493397!GO:0048468;cell development;0.0167551677652225!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0167677722284129!GO:0030027;lamellipodium;0.0167870331049199!GO:0019206;nucleoside kinase activity;0.0173882081730859!GO:0051540;metal cluster binding;0.0174077452456238!GO:0051536;iron-sulfur cluster binding;0.0174077452456238!GO:0005096;GTPase activator activity;0.0174077452456238!GO:0009081;branched chain family amino acid metabolic process;0.0175763634086193!GO:0040008;regulation of growth;0.0180029605129955!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0180749145469067!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0182953346135302!GO:0006509;membrane protein ectodomain proteolysis;0.0183090309256652!GO:0033619;membrane protein proteolysis;0.0183090309256652!GO:0035267;NuA4 histone acetyltransferase complex;0.0183465484876483!GO:0000123;histone acetyltransferase complex;0.0188935885225791!GO:0051098;regulation of binding;0.0190532011821448!GO:0005869;dynactin complex;0.0194079256413027!GO:0030119;AP-type membrane coat adaptor complex;0.0201134646708161!GO:0000209;protein polyubiquitination;0.0203399339484772!GO:0031529;ruffle organization and biogenesis;0.0203761625015211!GO:0000077;DNA damage checkpoint;0.0203761625015211!GO:0004448;isocitrate dehydrogenase activity;0.0209568666803544!GO:0043130;ubiquitin binding;0.0210849156943613!GO:0032182;small conjugating protein binding;0.0210849156943613!GO:0006807;nitrogen compound metabolic process;0.021174230022826!GO:0008629;induction of apoptosis by intracellular signals;0.0213512396056063!GO:0050811;GABA receptor binding;0.0215261992078201!GO:0006779;porphyrin biosynthetic process;0.0220638971103407!GO:0033014;tetrapyrrole biosynthetic process;0.0220638971103407!GO:0016407;acetyltransferase activity;0.0222959771685377!GO:0044433;cytoplasmic vesicle part;0.0223483257269382!GO:0031970;organelle envelope lumen;0.0223689652967717!GO:0008092;cytoskeletal protein binding;0.0234995682638656!GO:0051101;regulation of DNA binding;0.0235653247997525!GO:0030032;lamellipodium biogenesis;0.023688262785695!GO:0047485;protein N-terminus binding;0.0238081071956291!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0239287923401751!GO:0007021;tubulin folding;0.0240446096398422!GO:0006220;pyrimidine nucleotide metabolic process;0.024060434269726!GO:0006984;ER-nuclear signaling pathway;0.0240692752665705!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0241570227528732!GO:0051656;establishment of organelle localization;0.0242015124416273!GO:0016126;sterol biosynthetic process;0.0247298146009659!GO:0051053;negative regulation of DNA metabolic process;0.0250543617275088!GO:0031406;carboxylic acid binding;0.0258188994455756!GO:0046966;thyroid hormone receptor binding;0.0261052837333538!GO:0047115;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;0.0263547798647125!GO:0044437;vacuolar part;0.0264311344678821!GO:0005663;DNA replication factor C complex;0.0265687529018183!GO:0032906;transforming growth factor-beta2 production;0.0267595063455244!GO:0032909;regulation of transforming growth factor-beta2 production;0.0267595063455244!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0276515268635694!GO:0031371;ubiquitin conjugating enzyme complex;0.0277205098435499!GO:0008408;3'-5' exonuclease activity;0.0279991012032196!GO:0009308;amine metabolic process;0.0280170247425905!GO:0005784;translocon complex;0.0281265061536221!GO:0006783;heme biosynthetic process;0.0287700899396712!GO:0019798;procollagen-proline dioxygenase activity;0.0288424693559859!GO:0045045;secretory pathway;0.0290313934819975!GO:0006081;aldehyde metabolic process;0.0292793720337837!GO:0005765;lysosomal membrane;0.0293144052656668!GO:0006695;cholesterol biosynthetic process;0.0293578267931879!GO:0006897;endocytosis;0.0294454208594355!GO:0010324;membrane invagination;0.0294454208594355!GO:0032259;methylation;0.02956003795839!GO:0012506;vesicle membrane;0.0296463247169414!GO:0030131;clathrin adaptor complex;0.029769873125516!GO:0000228;nuclear chromosome;0.0300392461962632!GO:0009124;nucleoside monophosphate biosynthetic process;0.0300438912209164!GO:0009123;nucleoside monophosphate metabolic process;0.0300438912209164!GO:0006672;ceramide metabolic process;0.0300438912209164!GO:0008538;proteasome activator activity;0.0306777692974686!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0307485891681793!GO:0031543;peptidyl-proline dioxygenase activity;0.030990585351215!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0313873980223337!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0315323011640076!GO:0019783;small conjugating protein-specific protease activity;0.0316007287487815!GO:0000097;sulfur amino acid biosynthetic process;0.0316168573448671!GO:0009262;deoxyribonucleotide metabolic process;0.0317083657421392!GO:0004523;ribonuclease H activity;0.0317495863900034!GO:0007346;regulation of progression through mitotic cell cycle;0.0319474356414779!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0319474356414779!GO:0007041;lysosomal transport;0.0319745745847012!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0328209336877903!GO:0030508;thiol-disulfide exchange intermediate activity;0.0332541160733696!GO:0044450;microtubule organizing center part;0.0338352621987754!GO:0008610;lipid biosynthetic process;0.0338352621987754!GO:0000792;heterochromatin;0.0338769658954815!GO:0046128;purine ribonucleoside metabolic process;0.0339749303251249!GO:0042278;purine nucleoside metabolic process;0.0339749303251249!GO:0005875;microtubule associated complex;0.0343222748404617!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0345867976625819!GO:0030503;regulation of cell redox homeostasis;0.0346572348447517!GO:0050790;regulation of catalytic activity;0.0346572348447517!GO:0009893;positive regulation of metabolic process;0.0346572348447517!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0354346772170697!GO:0010257;NADH dehydrogenase complex assembly;0.0354346772170697!GO:0033108;mitochondrial respiratory chain complex assembly;0.0354346772170697!GO:0008287;protein serine/threonine phosphatase complex;0.0365470206289712!GO:0017134;fibroblast growth factor binding;0.0368069179251715!GO:0022415;viral reproductive process;0.0369888578486371!GO:0008536;Ran GTPase binding;0.0377052469160507!GO:0004843;ubiquitin-specific protease activity;0.0377324410440769!GO:0006360;transcription from RNA polymerase I promoter;0.0377369711341025!GO:0008097;5S rRNA binding;0.0377369711341025!GO:0051881;regulation of mitochondrial membrane potential;0.0381078043381036!GO:0005680;anaphase-promoting complex;0.0382996644310947!GO:0008601;protein phosphatase type 2A regulator activity;0.0385849761614177!GO:0016790;thiolester hydrolase activity;0.0387026461767084!GO:0006790;sulfur metabolic process;0.0387512368449581!GO:0044438;microbody part;0.0391508649072961!GO:0044439;peroxisomal part;0.0391508649072961!GO:0030911;TPR domain binding;0.0392204329813402!GO:0033239;negative regulation of amine metabolic process;0.039223846325945!GO:0045763;negative regulation of amino acid metabolic process;0.039223846325945!GO:0001933;negative regulation of protein amino acid phosphorylation;0.039223846325945!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.039223846325945!GO:0043631;RNA polyadenylation;0.0398697260576767!GO:0007264;small GTPase mediated signal transduction;0.04001324114895!GO:0006118;electron transport;0.0411482610148418!GO:0030029;actin filament-based process;0.0417005889466223!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0417628772174207!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0417628772174207!GO:0008276;protein methyltransferase activity;0.0420116525666008!GO:0000118;histone deacetylase complex;0.0420116525666008!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0420738414373466!GO:0009066;aspartate family amino acid metabolic process;0.0443711468763618!GO:0000178;exosome (RNase complex);0.0445184838152629!GO:0000781;chromosome, telomeric region;0.0445958290931448!GO:0008286;insulin receptor signaling pathway;0.0446503470625023!GO:0008320;protein transmembrane transporter activity;0.0453629150691347!GO:0030125;clathrin vesicle coat;0.0456612663651446!GO:0030665;clathrin coated vesicle membrane;0.0456612663651446!GO:0007569;cell aging;0.0457862863952485!GO:0005881;cytoplasmic microtubule;0.0457862863952485!GO:0007004;telomere maintenance via telomerase;0.0466947261479295!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0476429523304757!GO:0045039;protein import into mitochondrial inner membrane;0.0476429523304757!GO:0043433;negative regulation of transcription factor activity;0.0477586531024194!GO:0043414;biopolymer methylation;0.0478017149881257!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0478601647470598!GO:0016585;chromatin remodeling complex;0.0495922953894109!GO:0006541;glutamine metabolic process;0.0496872879281732!GO:0009070;serine family amino acid biosynthetic process;0.0499414956927593 | |||
|sample_id=10485 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=brain | |||
|top_motifs=NKX6-1,2:1.76766026243;T:1.7186397953;RBPJ:1.47170485804;PAX1,9:1.46405011153;NFY{A,B,C}:1.33967738263;E2F1..5:1.31748549182;EN1,2:1.23152699739;TFDP1:1.22912994305;FOXL1:1.21451980334;GFI1:1.19797883381;HSF1,2:0.995395073218;NKX2-2,8:0.99268455707;ZNF143:0.790981228365;TEF:0.77505571629;NFE2L2:0.746943880234;PITX1..3:0.721281297182;POU5F1:0.710027566745;FOXA2:0.700795549628;MYB:0.689151681505;EVI1:0.677348854123;ELK1,4_GABP{A,B1}:0.658394638173;LEF1_TCF7_TCF7L1,2:0.657056576518;NKX2-3_NKX2-5:0.648788210494;FOXD3:0.596228112201;TLX1..3_NFIC{dimer}:0.592384572944;CDX1,2,4:0.579393583645;MYBL2:0.574186230785;NRF1:0.565107580684;IRF1,2:0.559505437611;FOXP1:0.545334922882;NR3C1:0.530880717921;PRDM1:0.519450639234;HMGA1,2:0.514375352771;MAZ:0.499394959809;PBX1:0.475188611676;YY1:0.471809125716;PAX8:0.470000437839;SOX{8,9,10}:0.445247622836;IKZF1:0.443018284741;STAT5{A,B}:0.442274310665;PRRX1,2:0.428823240737;SOX17:0.413025026352;NFE2:0.407456540003;SOX2:0.392709704082;PATZ1:0.361824427832;ARID5B:0.349365202487;GTF2A1,2:0.343327895538;BPTF:0.327991300767;FOXO1,3,4:0.323189862874;GATA4:0.315311780264;MZF1:0.288073542535;SOX5:0.281636528164;CEBPA,B_DDIT3:0.277481459087;FOX{I1,J2}:0.268087344249;ELF1,2,4:0.239569208983;LHX3,4:0.230551285484;SP1:0.226760247038;CRX:0.226676366384;PAX3,7:0.206367738471;HAND1,2:0.185164514534;PAX4:0.170601778247;TEAD1:0.162962131957;FOXP3:0.156553178874;XCPE1{core}:0.151747527021;FOX{F1,F2,J1}:0.151075780644;NFIX:0.145386187669;EBF1:0.139448066691;HOX{A5,B5}:0.123649870299;NKX3-1:0.118131055288;BREu{core}:0.109037298181;RXR{A,B,G}:0.0873494335122;PAX5:0.0802702521778;ZIC1..3:0.0696820148373;ADNP_IRX_SIX_ZHX:0.0625670365408;UFEwm:0.0556632118933;RFX1:0.0551325544777;BACH2:0.0455738519661;TFAP2B:0.0437465873861;DBP:0.0369350233811;CDC5L:0.0218521456368;CUX2:0.00398782170216;HNF1A:0.000853778029828;RORA:-0.00459847675071;HBP1_HMGB_SSRP1_UBTF:-0.0169622587641;MTE{core}:-0.0181893897265;AHR_ARNT_ARNT2:-0.0192029838904;GTF2I:-0.0200164122294;HNF4A_NR2F1,2:-0.0264541459194;TFCP2:-0.0305161733094;NFATC1..3:-0.0322105336878;AIRE:-0.0342821988603;NKX2-1,4:-0.0509001310797;POU2F1..3:-0.0530933422254;FOX{D1,D2}:-0.0572889045467;OCT4_SOX2{dimer}:-0.0667401948297;ATF4:-0.0690632357741;TBX4,5:-0.0695486317011;HOX{A4,D4}:-0.0814303631711;HLF:-0.0837105270593;ZNF423:-0.0862561417415;KLF4:-0.0902840384102;VSX1,2:-0.116568649487;PAX6:-0.121316951623;MED-1{core}:-0.128983199166;IKZF2:-0.134212299054;HES1:-0.135154695593;SPIB:-0.138739181475;MYFfamily:-0.143732856179;HOXA9_MEIS1:-0.147858307544;TBP:-0.170736015331;bHLH_family:-0.1739859686;IRF7:-0.177492743182;XBP1:-0.17818900057;ZFP161:-0.179909110635;ZBTB6:-0.184549868046;FOXQ1:-0.187336049439;ZNF384:-0.196444651447;TP53:-0.203034716764;POU1F1:-0.207726064136;MEF2{A,B,C,D}:-0.212648490596;ATF5_CREB3:-0.222618483768;ZBTB16:-0.224649659365;EGR1..3:-0.234438413613;FOS_FOS{B,L1}_JUN{B,D}:-0.239690319762;FOSL2:-0.254469270246;NKX3-2:-0.256994004433;ALX4:-0.271367384672;MAFB:-0.271403498363;SRF:-0.27365571056;TOPORS:-0.276681742474;NFE2L1:-0.277038243014;HIC1:-0.288419464078;RUNX1..3:-0.310244189778;GFI1B:-0.336161633158;POU6F1:-0.34795428898;NFKB1_REL_RELA:-0.356366296756;RFX2..5_RFXANK_RFXAP:-0.363330412931;TAL1_TCF{3,4,12}:-0.381777789695;MTF1:-0.390580409141;FOXM1:-0.419168822404;HOX{A6,A7,B6,B7}:-0.42615428357;NR1H4:-0.431233311475;GATA6:-0.447305176898;PDX1:-0.447460499847;ETS1,2:-0.452522619342;PPARG:-0.461305647521;RREB1:-0.470679125556;HMX1:-0.489953673693;SPI1:-0.492623195506;STAT1,3:-0.498016848844;NR5A1,2:-0.504603170846;ZNF238:-0.522424053304;SPZ1:-0.527497982487;DMAP1_NCOR{1,2}_SMARC:-0.539225667443;NFIL3:-0.556954193998;TFAP2{A,C}:-0.561953439924;ONECUT1,2:-0.569182133775;FOXN1:-0.584383076549;ESR1:-0.58802834115;REST:-0.600463119527;JUN:-0.603218172938;GCM1,2:-0.628211668709;NANOG:-0.636206502231;TLX2:-0.642000710106;GZF1:-0.643422309353;EP300:-0.669480709032;ATF2:-0.677749858652;CREB1:-0.680716536155;STAT2,4,6:-0.688638169024;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.701651075985;NANOG{mouse}:-0.709785175065;ZNF148:-0.736800337074;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.739890081268;SNAI1..3:-0.760610108553;NHLH1,2:-0.761315803267;HIF1A:-0.773034412327;NR6A1:-0.792585956088;POU3F1..4:-0.799308779911;ZEB1:-0.810615143705;TGIF1:-0.844220861095;PAX2:-0.854991772921;ATF6:-0.863719068749;MYOD1:-0.868755473414;AR:-0.87999194846;SMAD1..7,9:-0.913497226366;RXRA_VDR{dimer}:-0.934744925168;ESRRA:-0.946723755963;ALX1:-0.963610370772;SREBF1,2:-1.09902456133;TFAP4:-1.15580734675;LMO2:-1.15840697999;GLI1..3:-1.31373667559 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10485-107A8;search_select_hide=table117:FF:10485-107A8 | |||
}} | }} |
Latest revision as of 14:26, 3 June 2020
Name: | glioblastoma cell line:T98G |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11272 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11272
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11272
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.778 |
10 | 10 | 0.454 |
100 | 100 | 0.397 |
101 | 101 | 0.415 |
102 | 102 | 0.551 |
103 | 103 | 0.501 |
104 | 104 | 0.761 |
105 | 105 | 0.843 |
106 | 106 | 0.00103 |
107 | 107 | 0.178 |
108 | 108 | 0.53 |
109 | 109 | 0.205 |
11 | 11 | 0.594 |
110 | 110 | 0.95 |
111 | 111 | 0.707 |
112 | 112 | 0.00902 |
113 | 113 | 0.663 |
114 | 114 | 0.361 |
115 | 115 | 0.225 |
116 | 116 | 0.392 |
117 | 117 | 0.75 |
118 | 118 | 0.939 |
119 | 119 | 0.197 |
12 | 12 | 0.463 |
120 | 120 | 0.829 |
121 | 121 | 0.427 |
122 | 122 | 0.598 |
123 | 123 | 0.349 |
124 | 124 | 0.472 |
125 | 125 | 0.442 |
126 | 126 | 0.289 |
127 | 127 | 0.336 |
128 | 128 | 4.95285e-4 |
129 | 129 | 0.00215 |
13 | 13 | 0.782 |
130 | 130 | 0.00326 |
131 | 131 | 0.0995 |
132 | 132 | 0.542 |
133 | 133 | 0.294 |
134 | 134 | 0.673 |
135 | 135 | 0.201 |
136 | 136 | 0.631 |
137 | 137 | 0.255 |
138 | 138 | 0.456 |
139 | 139 | 0.00824 |
14 | 14 | 0.489 |
140 | 140 | 0.796 |
141 | 141 | 0.396 |
142 | 142 | 0.802 |
143 | 143 | 0.0677 |
144 | 144 | 0.769 |
145 | 145 | 0.106 |
146 | 146 | 0.59 |
147 | 147 | 0.874 |
148 | 148 | 0.281 |
149 | 149 | 0.169 |
15 | 15 | 0.49 |
150 | 150 | 0.909 |
151 | 151 | 0.153 |
152 | 152 | 0.134 |
153 | 153 | 0.237 |
154 | 154 | 0.256 |
155 | 155 | 0.00757 |
156 | 156 | 0.811 |
157 | 157 | 0.904 |
158 | 158 | 0.149 |
159 | 159 | 0.627 |
16 | 16 | 0.313 |
160 | 160 | 0.0729 |
161 | 161 | 0.701 |
162 | 162 | 0.559 |
163 | 163 | 0.495 |
164 | 164 | 0.41 |
165 | 165 | 0.605 |
166 | 166 | 0.818 |
167 | 167 | 0.83 |
168 | 168 | 0.616 |
169 | 169 | 0.16 |
17 | 17 | 0.236 |
18 | 18 | 0.266 |
19 | 19 | 0.608 |
2 | 2 | 0.178 |
20 | 20 | 0.78 |
21 | 21 | 0.967 |
22 | 22 | 0.365 |
23 | 23 | 0.123 |
24 | 24 | 0.549 |
25 | 25 | 0.464 |
26 | 26 | 0.572 |
27 | 27 | 0.205 |
28 | 28 | 0.898 |
29 | 29 | 0.66 |
3 | 3 | 0.605 |
30 | 30 | 0.876 |
31 | 31 | 0.145 |
32 | 32 | 0.056 |
33 | 33 | 0.377 |
34 | 34 | 0.305 |
35 | 35 | 0.344 |
36 | 36 | 0.333 |
37 | 37 | 0.257 |
38 | 38 | 0.264 |
39 | 39 | 0.752 |
4 | 4 | 0.611 |
40 | 40 | 0.273 |
41 | 41 | 0.143 |
42 | 42 | 0.723 |
43 | 43 | 0.0775 |
44 | 44 | 0.202 |
45 | 45 | 0.487 |
46 | 46 | 0.27 |
47 | 47 | 0.836 |
48 | 48 | 0.672 |
49 | 49 | 0.0843 |
5 | 5 | 0.508 |
50 | 50 | 0.841 |
51 | 51 | 0.216 |
52 | 52 | 0.178 |
53 | 53 | 0.956 |
54 | 54 | 0.376 |
55 | 55 | 0.51 |
56 | 56 | 0.701 |
57 | 57 | 0.595 |
58 | 58 | 0.354 |
59 | 59 | 0.0953 |
6 | 6 | 0.831 |
60 | 60 | 0.0676 |
61 | 61 | 0.464 |
62 | 62 | 0.0655 |
63 | 63 | 0.468 |
64 | 64 | 0.422 |
65 | 65 | 0.142 |
66 | 66 | 0.00416 |
67 | 67 | 0.533 |
68 | 68 | 0.455 |
69 | 69 | 0.423 |
7 | 7 | 0.449 |
70 | 70 | 0.0145 |
71 | 71 | 0.697 |
72 | 72 | 0.365 |
73 | 73 | 0.174 |
74 | 74 | 0.0277 |
75 | 75 | 0.48 |
76 | 76 | 0.848 |
77 | 77 | 0.285 |
78 | 78 | 0.194 |
79 | 79 | 0.415 |
8 | 8 | 0.429 |
80 | 80 | 0.381 |
81 | 81 | 0.315 |
82 | 82 | 0.0739 |
83 | 83 | 0.895 |
84 | 84 | 0.911 |
85 | 85 | 0.00116 |
86 | 86 | 0.379 |
87 | 87 | 0.374 |
88 | 88 | 0.319 |
89 | 89 | 0.0498 |
9 | 9 | 0.337 |
90 | 90 | 0.827 |
91 | 91 | 0.119 |
92 | 92 | 0.0204 |
93 | 93 | 0.334 |
94 | 94 | 0.983 |
95 | 95 | 0.278 |
96 | 96 | 0.233 |
97 | 97 | 0.82 |
98 | 98 | 0.0788 |
99 | 99 | 0.829 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11272
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101583 T-98G cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002371 (somatic cell)
0002319 (neural cell)
0000095 (neuron associated cell)
0000243 (glial cell (sensu Vertebrata))
0000125 (glial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
3093 (nervous system cancer)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000955 (brain)
0004121 (ectoderm-derived structure)
0011216 (organ system subdivision)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0010317 (germ layer / neural crest derived structure)
0001017 (central nervous system)
0001016 (nervous system)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0101530 (glioblastoma cell line sample)
0100711 (glioma cell line sample)
0100255 (brain cell line sample)
0100690 (brain cancer cell line sample)
0101531 (glial cell line sample)
0101583 (T-98G cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000133 (neurectodermal cell)
CL:0000339 (glioblast (sensu Vertebrata))
CL:0000221 (ectodermal cell)
UBERON:0002532 (epiblast (generic))
UBERON:0006601 (presumptive ectoderm)
UBERON:0006238 (future brain)
UBERON:0010316 (germ layer / neural crest)