FF:10839-111E2: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004922 | ||
| | |accession_numbers=CAGE;DRX007912;DRR008784;DRZ000209;DRZ001594;DRZ011559;DRZ012944 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002048,UBERON:0002100,UBERON:0000483,UBERON:0000479,UBERON:0000064,UBERON:0004119,UBERON:0000466,UBERON:0000062,UBERON:0004111,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0004802,UBERON:0000025,UBERON:0005911,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0009569,UBERON:0005178,UBERON:0000072,UBERON:0005177,UBERON:0004807,UBERON:0000117,UBERON:0000171,UBERON:0000115,UBERON:0000464,UBERON:0005181,UBERON:0010317,UBERON:0000065,UBERON:0000170,UBERON:0001004,UBERON:0002224,UBERON:0000915 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000082,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:0050615,DOID:162,DOID:14566,DOID:0050687,DOID:1324,DOID:305,DOID:3905,DOID:3908,DOID:4556 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100297,FF:0100353,FF:0101120,FF:0100762,FF:0102205,FF:0102207 | |||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr6:166582133..166582149,-!p1@T!2.63!424.37!T;;chr6:1312325..1312340,+!p1@FOXQ1!2.41!411.64!FOXQ1;;chr6:166581333..166581349,-!p2@T!2.12!131.42!T;;chr10:35484053..35484076,+!p1@CREM!1.85!168.35!CREM;;chr6:126240442..126240459,+!p4@NCOA7!1.85!88.57!NCOA7;;chr12:52445218..52445237,+!p1@NR4A1!1.80!734.90!NR4A1;;chr4:57547454..57547469,-!p1@HOPX!1.76!56.12!HOPX;;chr5:2751762..2751784,-!p1@IRX2!1.68!46.61!IRX2;;chr6:126240463..126240489,+!p6@NCOA7!1.61!44.82!NCOA7;;chr17:41622765..41622821,-!p2@ETV4!1.57!54.86!ETV4;;chr6:126240380..126240430,+!p2@NCOA7!1.56!89.82!NCOA7;;chr2:157189180..157189290,-!p1@NR4A2!1.54!168.71!NR4A2;;chr21:47063625..47063658,+!p1@PCBP3!1.54!142.35!PCBP3;;chr16:67198633..67198671,+!p1@HSF4!1.48!29.04!HSF4;;chr17:41622731..41622764,-!p5@ETV4!1.43!25.64!ETV4;;chr5:134369905..134369972,-!p1@PITX1!1.42!38.01!PITX1;;chr16:67198683..67198698,+!p2@HSF4!1.42!25.10!HSF4;;chr6:10415276..10415341,-!p2@TFAP2A!1.41!29.76!TFAP2A;;chr10:35484090..35484104,+!p6@CREM!1.40!24.20!CREM;;chr9:110251836..110251887,-!p4@KLF4!1.38!30.12!KLF4;;chr6:1312753..1312800,+!p4@FOXQ1!1.38!22.95!FOXQ1;;chr7:14028488..14028516,-!p2@ETV1!1.37!24.74!ETV1;;chr9:102584262..102584276,+!p1@NR4A3!1.35!46.61!NR4A3;;chr9:110250697..110250738,-!p2@KLF4!1.29!21.87!KLF4;;chr6:1610293..1610310,+!p1@FOXC1!1.27!29.58!FOXC1;;chr6:166581938..166581955,-!p3@T!1.26!17.21!T;;chr17:70117153..70117174,+!p1@SOX9!1.25!170.50!SOX9;;chr17:8027418..8027432,-!p1@HES7!1.25!16.67!HES7;;chr6:10412600..10412637,-!p1@TFAP2A!1.22!26.00!TFAP2A;;chr17:41622925..41622976,-!p3@ETV4!1.21!22.59!ETV4;;chr17:46682321..46682362,-!p1@HOXB6!1.21!15.24!HOXB6;;chrX:30327504..30327509,-!p1@NR0B1!1.19!14.52!NR0B1;;chr17:41623692..41623715,-!p1@ETV4!1.18!59.52!ETV4;;chr3:141105705..141105770,+!p4@ZBTB38!1.18!17.03!ZBTB38;;chrY:21906594..21906622,-!p1@KDM5D!1.18!14.16!KDM5D;;chr5:134369879..134369898,-!p2@PITX1!1.16!13.45!PITX1;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!1.13!12.55!SEBOX;;chr7:1570388..1570418,+!p2@MAFK!1.12!26.36!MAFK;;chr6:1389789..1389821,+!p1@FOXF2!1.12!16.85!FOXF2;;chr6:126240542..126240553,+!p14@NCOA7!1.12!12.19!NCOA7;;chr5:2751785..2751808,-!p2@IRX2!1.11!12.01!IRX2;;chr16:54320101..54320125,-!p4@IRX3!1.10!16.67!IRX3;;chr6:126240490..126240501,+!p11@NCOA7!1.10!11.47!NCOA7;;chr3:193853927..193853944,+!p1@HES1!1.09!367.36!HES1;;chr9:110252035..110252057,-!p1@KLF4!1.07!172.12!KLF4;;chr17:59477233..59477263,+!p1@TBX2!1.07!33.89!TBX2;;chr8:128749984..128750033,+!p4@MYC!1.06!38.19!MYC;;chr14:38064429..38064486,-!p1@FOXA1!1.06!10.40!FOXA1;;chr1:151032782..151032801,+!p4@MLLT11!1.05!20.80!MLLT11;;chr1:151032860..151032918,+!p1@MLLT11!1.04!119.76!MLLT11;;chr7:1577111..1577132,+!p4@MAFK!1.02!10.58!MAFK;;chr7:28448965..28448994,+!p2@CREB5!1.00!32.45!CREB5;;chr6:126240356..126240379,+!p7@NCOA7!0.99!10.94!NCOA7;;chr2:176994408..176994492,+!p1@HOXD8!0.97!8.43!HOXD8;;chr20:6748325..6748352,+!p1@BMP2!0.95!11.47!BMP2;;chr5:137804484..137804498,+!p2@EGR1!0.94!32.09!EGR1;;chr7:14029283..14029311,-!p1@ETV1!0.93!41.42!ETV1;;chr7:150945754..150945789,-!p2@SMARCD3!0.93!23.85!SMARCD3;;chr17:41622834..41622883,-!p6@ETV4!0.93!9.14!ETV4;;chr7:14026022..14026044,-!p7@ETV1!0.93!7.53!ETV1;;chr9:102584241..102584261,+!p4@NR4A3!0.92!11.47!NR4A3;;chr7:27190547..27190591,-!p1@HOXA6!0.90!6.99!HOXA6;;chr17:26697304..26697335,-!p1@SEBOX,p1@VTN!0.89!6.81!SEBOX;;chr12:52450298..52450331,+!p11@NR4A1!0.89!6.81!NR4A1;;chr9:102584159..102584174,+!p2@NR4A3!0.88!12.37!NR4A3;;chr6:166581324..166581327,-!p7@T!0.88!6.63!T;;chr12:52448213..52448262,+!p6@NR4A1!0.88!6.63!NR4A1;;chr2:239756671..239756732,+!p1@TWIST2!0.87!21.87!TWIST2;;chr2:19558373..19558392,-!p1@OSR1!0.87!18.29!OSR1;;chr3:141121847..141121868,+!p5@ZBTB38!0.87!10.04!ZBTB38;;chr6:1312155..1312187,+!p2@FOXQ1!0.86!6.28!FOXQ1;;chr8:128750654..128750793,+!p3@MYC!0.85!25.64!MYC;;chr15:60884706..60884743,-!p1@RORA!0.83!32.09!RORA;;chr17:41623259..41623278,-!p7@ETV4!0.83!6.81!ETV4;;chr2:101436564..101436647,+!p1@NPAS2!0.82!121.74!NPAS2;;chrX:106960180..106960197,-!p2@TSC22D3!0.82!22.59!TSC22D3;;chr3:5021268..5021282,+!p4@BHLHE40!0.82!12.01!BHLHE40;;chr2:157186630..157186686,-!p6@NR4A2!0.82!5.56!NR4A2;;chr16:54320617..54320643,-!p3@IRX3!0.81!7.17!IRX3;;chr2:101591314..101591333,+!p2@NPAS2!0.80!6.10!NPAS2;;chr6:10412392..10412409,-!p4@TFAP2A!0.80!6.10!TFAP2A;;chr9:102584278..102584285,+!p5@NR4A3!0.80!5.38!NR4A3;;chr14:95236440..95236465,-!p1@GSC!0.80!5.38!GSC;;chr17:41623009..41623053,-!p4@ETV4!0.79!8.61!ETV4;;chr5:92918956..92918969,+!p4@NR2F1!0.79!5.74!NR2F1;;chr8:103665947..103665981,-!p3@KLF10!0.78!7.35!KLF10;;chr8:128747757..128747800,+!p7@MYC!0.77!6.81!MYC;;chr17:59477275..59477286,+!p3@TBX2!0.77!6.63!TBX2;;chr6:1612300..1612324,+!p3@FOXC1!0.77!4.84!FOXC1;;chr19:16435625..16435682,+!p1@KLF2!0.75!167.10!KLF2;;chr17:46687959..46688007,-!p2@HOXB7!0.75!6.63!HOXB7;;chr16:54320280..54320291,-!p9@IRX3!0.75!4.66!IRX3;;chr6:1312688..1312701,+!p3@FOXQ1!0.75!4.66!FOXQ1;;chr6:21597765..21597779,+!p2@SOX4!0.74!39.98!SOX4;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| |||
|ffid_belonging_in_development=UBERON:0001041,UBERON:0008947,UBERON:0002532,UBERON:0006595,UBERON:0010316 | |||
|fonse_cell_line=FF:0100353,FF:0101120 | |fonse_cell_line=FF:0100353,FF:0101120 | ||
|fonse_cell_line_closure=FF:0100353,FF:0101120 | |fonse_cell_line_closure=FF:0100353,FF:0101120 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/large%2520cell%2520lung%2520carcinoma%2520cell%2520line%253aNCI-H460.CNhs12806.10839-111E2.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/large%2520cell%2520lung%2520carcinoma%2520cell%2520line%253aNCI-H460.CNhs12806.10839-111E2.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/large%2520cell%2520lung%2520carcinoma%2520cell%2520line%253aNCI-H460.CNhs12806.10839-111E2.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/large%2520cell%2520lung%2520carcinoma%2520cell%2520line%253aNCI-H460.CNhs12806.10839-111E2.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/large%2520cell%2520lung%2520carcinoma%2520cell%2520line%253aNCI-H460.CNhs12806.10839-111E2.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10839-111E2 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0102207 | |||
|is_obsolete= | |||
|library_id=CNhs12806 | |||
|library_id_phase_based=2:CNhs12806 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10839 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10839 | |||
|name=large cell lung carcinoma cell line:NCI-H460 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12806,LSID972,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=0.43567 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.47 | |||
|rna_od260/280=1.91 | |||
|rna_position=E2 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=1.11E+04 | |||
|rna_weight_ug=17.4268 | |||
|sample_age=unknown | |||
|sample_category=cell lines | |||
|sample_cell_catalog=HTB177 | |||
|sample_cell_line=NCI-H460 | |||
|sample_cell_lot= | |||
|sample_cell_type=unclassifiable | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=ATCC | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=large cell lung carcinoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.24159489140144e-226!GO:0005737;cytoplasm;1.33114345528448e-191!GO:0043231;intracellular membrane-bound organelle;7.6576667865797e-188!GO:0043227;membrane-bound organelle;1.2841190335411e-187!GO:0043226;organelle;1.22652164118686e-183!GO:0043229;intracellular organelle;3.22667427977333e-183!GO:0044444;cytoplasmic part;2.74484829955736e-156!GO:0044422;organelle part;2.88943570748089e-139!GO:0044446;intracellular organelle part;1.11324952722259e-137!GO:0032991;macromolecular complex;9.95075252762149e-98!GO:0030529;ribonucleoprotein complex;2.35369766900433e-96!GO:0044237;cellular metabolic process;5.56184969644368e-92!GO:0044238;primary metabolic process;2.14925798239409e-90!GO:0005739;mitochondrion;7.73156929732879e-86!GO:0003723;RNA binding;3.12300524415576e-79!GO:0043233;organelle lumen;2.49643080056407e-78!GO:0031974;membrane-enclosed lumen;2.49643080056407e-78!GO:0043170;macromolecule metabolic process;1.69820709546854e-77!GO:0044428;nuclear part;2.40882497708317e-69!GO:0005840;ribosome;6.02744478481119e-61!GO:0005515;protein binding;2.40845287289964e-60!GO:0005634;nucleus;2.77348076648477e-60!GO:0031090;organelle membrane;8.14876803222241e-58!GO:0006412;translation;1.18312466467937e-56!GO:0044429;mitochondrial part;9.06385262283601e-54!GO:0006396;RNA processing;1.13977525999209e-53!GO:0003735;structural constituent of ribosome;1.35798226148164e-51!GO:0009058;biosynthetic process;5.47102594351856e-51!GO:0019538;protein metabolic process;2.56206437777289e-49!GO:0044249;cellular biosynthetic process;6.9692104399892e-49!GO:0043234;protein complex;5.40173509584261e-46!GO:0031967;organelle envelope;9.14776696703455e-46!GO:0031975;envelope;1.75875017369344e-45!GO:0044260;cellular macromolecule metabolic process;5.26643288706468e-45!GO:0015031;protein transport;5.26643288706468e-45!GO:0033279;ribosomal subunit;8.23900020724364e-45!GO:0005829;cytosol;8.23900020724364e-45!GO:0009059;macromolecule biosynthetic process;8.86692758188317e-45!GO:0044267;cellular protein metabolic process;2.41864029574005e-44!GO:0031981;nuclear lumen;4.15343568849779e-44!GO:0033036;macromolecule localization;1.50284739645211e-43!GO:0045184;establishment of protein localization;1.74719872740491e-41!GO:0016043;cellular component organization and biogenesis;1.98938230567011e-41!GO:0008104;protein localization;1.07551647293763e-40!GO:0043283;biopolymer metabolic process;2.55632407206895e-39!GO:0010467;gene expression;5.14951442269127e-39!GO:0016071;mRNA metabolic process;1.13840073486058e-38!GO:0005740;mitochondrial envelope;3.29499016526457e-35!GO:0008380;RNA splicing;1.2020405964401e-34!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.39809647002712e-33!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.6351253380413e-33!GO:0006397;mRNA processing;4.13851363540216e-33!GO:0031966;mitochondrial membrane;6.82880264644085e-33!GO:0019866;organelle inner membrane;1.15926143016153e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);5.1106059012415e-32!GO:0046907;intracellular transport;1.03754318285169e-31!GO:0005743;mitochondrial inner membrane;2.19880695742316e-30!GO:0065003;macromolecular complex assembly;2.07708851192811e-28!GO:0006886;intracellular protein transport;2.27114959788442e-27!GO:0044445;cytosolic part;1.26243578819621e-25!GO:0006996;organelle organization and biogenesis;1.4625486415314e-25!GO:0005681;spliceosome;3.76843316931191e-25!GO:0005654;nucleoplasm;4.40597800693834e-25!GO:0022607;cellular component assembly;5.59483629552282e-25!GO:0006119;oxidative phosphorylation;7.14317365984179e-24!GO:0012505;endomembrane system;1.29751568124564e-23!GO:0043228;non-membrane-bound organelle;2.91864273746889e-23!GO:0043232;intracellular non-membrane-bound organelle;2.91864273746889e-23!GO:0015935;small ribosomal subunit;4.20863984448653e-23!GO:0000166;nucleotide binding;6.72551108266526e-23!GO:0015934;large ribosomal subunit;8.5947430249825e-23!GO:0005783;endoplasmic reticulum;8.66175148558923e-23!GO:0044455;mitochondrial membrane part;8.83172957306646e-23!GO:0031980;mitochondrial lumen;1.32821858374909e-22!GO:0005759;mitochondrial matrix;1.32821858374909e-22!GO:0006457;protein folding;6.09212631381909e-22!GO:0051649;establishment of cellular localization;9.99169694763567e-22!GO:0005730;nucleolus;1.01245607815785e-21!GO:0051641;cellular localization;1.95457725584544e-21!GO:0016874;ligase activity;1.745329794745e-20!GO:0051186;cofactor metabolic process;2.57686618844832e-20!GO:0044451;nucleoplasm part;3.73329199649047e-20!GO:0006259;DNA metabolic process;6.8945902446688e-20!GO:0016462;pyrophosphatase activity;1.10813738722593e-19!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.18507521894048e-19!GO:0044265;cellular macromolecule catabolic process;1.19077728566693e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;1.54660302622737e-19!GO:0044432;endoplasmic reticulum part;3.65931858007698e-19!GO:0003676;nucleic acid binding;3.93161892243341e-19!GO:0022618;protein-RNA complex assembly;2.08890928959999e-18!GO:0017111;nucleoside-triphosphatase activity;2.72715541252918e-18!GO:0005746;mitochondrial respiratory chain;3.05969350297539e-18!GO:0044248;cellular catabolic process;1.41965233138047e-17!GO:0006512;ubiquitin cycle;1.69400060141744e-17!GO:0000502;proteasome complex (sensu Eukaryota);3.01101934693131e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.28112144927462e-17!GO:0043285;biopolymer catabolic process;3.78437119879744e-17!GO:0009057;macromolecule catabolic process;6.48707347937718e-17!GO:0044257;cellular protein catabolic process;7.9782820319984e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;8.77162001982448e-17!GO:0005761;mitochondrial ribosome;9.20928843108542e-17!GO:0000313;organellar ribosome;9.20928843108542e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);9.7998185262417e-17!GO:0006511;ubiquitin-dependent protein catabolic process;1.09761710108261e-16!GO:0006732;coenzyme metabolic process;1.37331450118974e-16!GO:0050136;NADH dehydrogenase (quinone) activity;1.37331450118974e-16!GO:0003954;NADH dehydrogenase activity;1.37331450118974e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.37331450118974e-16!GO:0008135;translation factor activity, nucleic acid binding;1.52685647967569e-16!GO:0019941;modification-dependent protein catabolic process;1.57078377634704e-16!GO:0043632;modification-dependent macromolecule catabolic process;1.57078377634704e-16!GO:0005794;Golgi apparatus;3.83833344203084e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.66238761862081e-16!GO:0042254;ribosome biogenesis and assembly;8.97113030374925e-16!GO:0016070;RNA metabolic process;1.12664928986394e-15!GO:0032553;ribonucleotide binding;1.29618596068589e-15!GO:0032555;purine ribonucleotide binding;1.29618596068589e-15!GO:0017076;purine nucleotide binding;1.3225408111082e-15!GO:0051082;unfolded protein binding;4.06748920029415e-15!GO:0008134;transcription factor binding;8.14981102850223e-15!GO:0042775;organelle ATP synthesis coupled electron transport;1.14188001863324e-14!GO:0042773;ATP synthesis coupled electron transport;1.14188001863324e-14!GO:0030964;NADH dehydrogenase complex (quinone);1.8961642738756e-14!GO:0045271;respiratory chain complex I;1.8961642738756e-14!GO:0005747;mitochondrial respiratory chain complex I;1.8961642738756e-14!GO:0048770;pigment granule;2.26366054327664e-14!GO:0042470;melanosome;2.26366054327664e-14!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.25448094917956e-14!GO:0030163;protein catabolic process;4.99374578345191e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;6.04498399481325e-14!GO:0005789;endoplasmic reticulum membrane;8.03955067168375e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.28558647033169e-13!GO:0016192;vesicle-mediated transport;1.76971430579828e-13!GO:0006974;response to DNA damage stimulus;2.59699015921277e-13!GO:0006399;tRNA metabolic process;3.21010582683893e-13!GO:0006605;protein targeting;3.50316358788469e-13!GO:0048193;Golgi vesicle transport;1.04408593944328e-12!GO:0003743;translation initiation factor activity;1.16531880450725e-12!GO:0032559;adenyl ribonucleotide binding;1.25989378297794e-12!GO:0000398;nuclear mRNA splicing, via spliceosome;1.6327587022599e-12!GO:0000375;RNA splicing, via transesterification reactions;1.6327587022599e-12!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.6327587022599e-12!GO:0016887;ATPase activity;1.71825109147231e-12!GO:0030554;adenyl nucleotide binding;1.82133566387004e-12!GO:0043412;biopolymer modification;2.19747289257216e-12!GO:0042623;ATPase activity, coupled;2.73679566455602e-12!GO:0005524;ATP binding;3.08630919324833e-12!GO:0009055;electron carrier activity;3.44648771654513e-12!GO:0012501;programmed cell death;9.46499689598661e-12!GO:0006413;translational initiation;1.05029704687964e-11!GO:0051188;cofactor biosynthetic process;1.14509415266908e-11!GO:0009056;catabolic process;1.65771846626368e-11!GO:0006915;apoptosis;1.96059096204996e-11!GO:0005635;nuclear envelope;2.30458163453548e-11!GO:0006163;purine nucleotide metabolic process;4.57287530665066e-11!GO:0044453;nuclear membrane part;7.38686996966337e-11!GO:0007049;cell cycle;8.96592030621359e-11!GO:0009259;ribonucleotide metabolic process;9.62216761171078e-11!GO:0006281;DNA repair;1.03966244645507e-10!GO:0031965;nuclear membrane;1.29181347875543e-10!GO:0016604;nuclear body;1.36586780391493e-10!GO:0006364;rRNA processing;1.39451240422236e-10!GO:0006164;purine nucleotide biosynthetic process;1.73777057585713e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.89843902427685e-10!GO:0006366;transcription from RNA polymerase II promoter;2.13348683410032e-10!GO:0006464;protein modification process;2.45475256492342e-10!GO:0016072;rRNA metabolic process;2.79706692206902e-10!GO:0008219;cell death;2.8904061924348e-10!GO:0016265;death;2.8904061924348e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.69987250328971e-10!GO:0006446;regulation of translational initiation;3.82372462492379e-10!GO:0003712;transcription cofactor activity;4.74092526005382e-10!GO:0007005;mitochondrion organization and biogenesis;5.41259318209855e-10!GO:0005793;ER-Golgi intermediate compartment;7.46813703290337e-10!GO:0009150;purine ribonucleotide metabolic process;7.67883931851109e-10!GO:0009719;response to endogenous stimulus;8.48980714033492e-10!GO:0009260;ribonucleotide biosynthetic process;9.8805236199465e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.08577304736526e-09!GO:0009108;coenzyme biosynthetic process;1.3643513625735e-09!GO:0009199;ribonucleoside triphosphate metabolic process;2.79685749537782e-09!GO:0004386;helicase activity;2.79685749537782e-09!GO:0009152;purine ribonucleotide biosynthetic process;3.04063409204048e-09!GO:0045333;cellular respiration;3.17861247904555e-09!GO:0009142;nucleoside triphosphate biosynthetic process;3.65056143572494e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.65056143572494e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.65056143572494e-09!GO:0004812;aminoacyl-tRNA ligase activity;3.65056143572494e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.65056143572494e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;3.73460756895989e-09!GO:0016491;oxidoreductase activity;3.91681013834507e-09!GO:0009141;nucleoside triphosphate metabolic process;4.07343758934617e-09!GO:0009060;aerobic respiration;4.68971201168752e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;6.32838775587125e-09!GO:0009144;purine nucleoside triphosphate metabolic process;6.32838775587125e-09!GO:0065002;intracellular protein transport across a membrane;6.33089869370909e-09!GO:0016787;hydrolase activity;7.86965365430746e-09!GO:0008639;small protein conjugating enzyme activity;8.27608397846511e-09!GO:0008565;protein transporter activity;8.53382302340781e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;8.59414039715091e-09!GO:0009145;purine nucleoside triphosphate biosynthetic process;8.59414039715091e-09!GO:0043038;amino acid activation;8.7951703004543e-09!GO:0006418;tRNA aminoacylation for protein translation;8.7951703004543e-09!GO:0043039;tRNA aminoacylation;8.7951703004543e-09!GO:0015078;hydrogen ion transmembrane transporter activity;9.21989841702691e-09!GO:0005768;endosome;9.89831900243563e-09!GO:0008026;ATP-dependent helicase activity;1.04342059000673e-08!GO:0005643;nuclear pore;1.0876748385891e-08!GO:0015986;ATP synthesis coupled proton transport;1.45666664606855e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.45666664606855e-08!GO:0006461;protein complex assembly;2.04429918148949e-08!GO:0004842;ubiquitin-protein ligase activity;2.5519341543323e-08!GO:0009117;nucleotide metabolic process;2.64640749190434e-08!GO:0006913;nucleocytoplasmic transport;2.71370262839719e-08!GO:0044431;Golgi apparatus part;2.73202332185676e-08!GO:0030532;small nuclear ribonucleoprotein complex;2.73969791386531e-08!GO:0019787;small conjugating protein ligase activity;3.26072347332217e-08!GO:0043687;post-translational protein modification;3.58917432498532e-08!GO:0016607;nuclear speck;4.41568618138784e-08!GO:0051169;nuclear transport;5.12157835051702e-08!GO:0019829;cation-transporting ATPase activity;5.49743807910877e-08!GO:0022402;cell cycle process;6.81833847533074e-08!GO:0006091;generation of precursor metabolites and energy;7.5052685614211e-08!GO:0016740;transferase activity;8.46755124219196e-08!GO:0016881;acid-amino acid ligase activity;1.47946548571203e-07!GO:0006403;RNA localization;1.55596566207593e-07!GO:0046034;ATP metabolic process;1.60879510409448e-07!GO:0050657;nucleic acid transport;1.60879510409448e-07!GO:0051236;establishment of RNA localization;1.60879510409448e-07!GO:0050658;RNA transport;1.60879510409448e-07!GO:0005839;proteasome core complex (sensu Eukaryota);1.60879510409448e-07!GO:0006325;establishment and/or maintenance of chromatin architecture;1.60879510409448e-07!GO:0006754;ATP biosynthetic process;1.91954939227404e-07!GO:0006753;nucleoside phosphate metabolic process;1.91954939227404e-07!GO:0005788;endoplasmic reticulum lumen;2.54504910443815e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.03994021215515e-07!GO:0051246;regulation of protein metabolic process;3.37182005820009e-07!GO:0000278;mitotic cell cycle;3.7421122330314e-07!GO:0017038;protein import;3.95097716499398e-07!GO:0006323;DNA packaging;4.05710463426945e-07!GO:0016779;nucleotidyltransferase activity;4.1330481213357e-07!GO:0006099;tricarboxylic acid cycle;4.49397066959679e-07!GO:0046356;acetyl-CoA catabolic process;4.49397066959679e-07!GO:0006260;DNA replication;4.98326303479834e-07!GO:0051276;chromosome organization and biogenesis;5.36335998744636e-07!GO:0051187;cofactor catabolic process;6.47533635938338e-07!GO:0006888;ER to Golgi vesicle-mediated transport;7.32247900337513e-07!GO:0043069;negative regulation of programmed cell death;8.03135661924657e-07!GO:0046930;pore complex;8.83311636863832e-07!GO:0045259;proton-transporting ATP synthase complex;9.2923289558815e-07!GO:0000245;spliceosome assembly;9.98201189037951e-07!GO:0006084;acetyl-CoA metabolic process;1.03852131550518e-06!GO:0000139;Golgi membrane;1.11243826066976e-06!GO:0009109;coenzyme catabolic process;1.17296502837415e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;1.20743667454247e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.25417425134147e-06!GO:0004298;threonine endopeptidase activity;1.34647627138515e-06!GO:0043066;negative regulation of apoptosis;1.41354675984208e-06!GO:0006752;group transfer coenzyme metabolic process;1.43354259186926e-06!GO:0008654;phospholipid biosynthetic process;1.63236128219497e-06!GO:0043067;regulation of programmed cell death;1.6712806474345e-06!GO:0005694;chromosome;1.67991703524576e-06!GO:0043623;cellular protein complex assembly;1.89216865175729e-06!GO:0042981;regulation of apoptosis;1.90609731090231e-06!GO:0043566;structure-specific DNA binding;2.16830860465613e-06!GO:0005773;vacuole;2.31907338273213e-06!GO:0030120;vesicle coat;2.44898844982514e-06!GO:0030662;coated vesicle membrane;2.44898844982514e-06!GO:0005770;late endosome;2.5987941434086e-06!GO:0005762;mitochondrial large ribosomal subunit;2.5987941434086e-06!GO:0000315;organellar large ribosomal subunit;2.5987941434086e-06!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.62854802507909e-06!GO:0065004;protein-DNA complex assembly;2.72312353198835e-06!GO:0006916;anti-apoptosis;2.79783594531446e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.26964243917298e-06!GO:0015399;primary active transmembrane transporter activity;3.26964243917298e-06!GO:0003713;transcription coactivator activity;3.94830556152353e-06!GO:0045454;cell redox homeostasis;4.73178759458471e-06!GO:0051028;mRNA transport;4.75651376727316e-06!GO:0015980;energy derivation by oxidation of organic compounds;4.87796787853877e-06!GO:0019752;carboxylic acid metabolic process;5.04371640965961e-06!GO:0016568;chromatin modification;5.41012559174745e-06!GO:0006082;organic acid metabolic process;5.8354262376042e-06!GO:0016853;isomerase activity;6.19253863984808e-06!GO:0032446;protein modification by small protein conjugation;6.6419083097802e-06!GO:0031988;membrane-bound vesicle;7.83335380264077e-06!GO:0003697;single-stranded DNA binding;8.30778806098963e-06!GO:0016567;protein ubiquitination;8.92064202300693e-06!GO:0044440;endosomal part;9.17930251549591e-06!GO:0010008;endosome membrane;9.17930251549591e-06!GO:0000074;regulation of progression through cell cycle;9.28597554548977e-06!GO:0016023;cytoplasmic membrane-bound vesicle;9.39715525468823e-06!GO:0051726;regulation of cell cycle;1.04061714660224e-05!GO:0000323;lytic vacuole;1.09544242752786e-05!GO:0005764;lysosome;1.09544242752786e-05!GO:0008033;tRNA processing;1.19556051236381e-05!GO:0003899;DNA-directed RNA polymerase activity;1.22485507732099e-05!GO:0048523;negative regulation of cellular process;1.22557915968554e-05!GO:0005667;transcription factor complex;1.38041216824376e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.40138033563654e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;1.40138033563654e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.54560184165279e-05!GO:0016563;transcription activator activity;1.70157128373157e-05!GO:0000314;organellar small ribosomal subunit;1.87495557544559e-05!GO:0005763;mitochondrial small ribosomal subunit;1.87495557544559e-05!GO:0006613;cotranslational protein targeting to membrane;1.87784055877584e-05!GO:0048475;coated membrane;1.89299606532327e-05!GO:0030117;membrane coat;1.89299606532327e-05!GO:0031982;vesicle;2.19279884895396e-05!GO:0031410;cytoplasmic vesicle;2.88721661512159e-05!GO:0044427;chromosomal part;3.01151646670777e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.10396400255283e-05!GO:0019843;rRNA binding;3.22921891997717e-05!GO:0016564;transcription repressor activity;3.39077321061516e-05!GO:0033116;ER-Golgi intermediate compartment membrane;3.43967071789628e-05!GO:0006793;phosphorus metabolic process;3.71873203314351e-05!GO:0006796;phosphate metabolic process;3.71873203314351e-05!GO:0003924;GTPase activity;3.84850254124323e-05!GO:0003724;RNA helicase activity;3.98206021085611e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.53407354958644e-05!GO:0044262;cellular carbohydrate metabolic process;5.09825273791351e-05!GO:0006333;chromatin assembly or disassembly;5.55832021122397e-05!GO:0006414;translational elongation;5.72567169185207e-05!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;5.90264298680729e-05!GO:0043021;ribonucleoprotein binding;6.08587652923267e-05!GO:0009165;nucleotide biosynthetic process;6.38007714783339e-05!GO:0000151;ubiquitin ligase complex;6.55629446220536e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;6.63344419591223e-05!GO:0031324;negative regulation of cellular metabolic process;7.00455545429598e-05!GO:0043492;ATPase activity, coupled to movement of substances;7.00455545429598e-05!GO:0051427;hormone receptor binding;8.15224040859876e-05!GO:0006383;transcription from RNA polymerase III promoter;8.70848428824634e-05!GO:0000785;chromatin;8.72413993790731e-05!GO:0046474;glycerophospholipid biosynthetic process;8.72413993790731e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;8.93281558256807e-05!GO:0019867;outer membrane;9.67352826907313e-05!GO:0043681;protein import into mitochondrion;9.83362040043334e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000100555329002532!GO:0006626;protein targeting to mitochondrion;0.000118524645718648!GO:0005525;GTP binding;0.000125158350680956!GO:0000087;M phase of mitotic cell cycle;0.00012835497171361!GO:0048519;negative regulation of biological process;0.000130883130588426!GO:0046467;membrane lipid biosynthetic process;0.000131871457710682!GO:0031968;organelle outer membrane;0.00013376000731628!GO:0005798;Golgi-associated vesicle;0.000141203820110859!GO:0046489;phosphoinositide biosynthetic process;0.000145961254576631!GO:0007067;mitosis;0.000156075501685458!GO:0035257;nuclear hormone receptor binding;0.000174596265043601!GO:0005813;centrosome;0.000178129912154287!GO:0009892;negative regulation of metabolic process;0.000179267580772435!GO:0007006;mitochondrial membrane organization and biogenesis;0.000179477138878834!GO:0016859;cis-trans isomerase activity;0.000182181146815328!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000182181146815328!GO:0006839;mitochondrial transport;0.00019698116651561!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00019698116651561!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000211331855823863!GO:0005769;early endosome;0.000238868837030674!GO:0030880;RNA polymerase complex;0.000242736501276575!GO:0030867;rough endoplasmic reticulum membrane;0.000256884119743164!GO:0051170;nuclear import;0.000256884119743164!GO:0006672;ceramide metabolic process;0.00028200204862084!GO:0016310;phosphorylation;0.000285482686926052!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000285640518028351!GO:0022403;cell cycle phase;0.00029163086116386!GO:0015630;microtubule cytoskeleton;0.00031052184275935!GO:0003714;transcription corepressor activity;0.000310655056253402!GO:0044452;nucleolar part;0.000317644460059129!GO:0005815;microtubule organizing center;0.000337688125789119!GO:0048471;perinuclear region of cytoplasm;0.000361437075266399!GO:0050662;coenzyme binding;0.000363904972116958!GO:0005741;mitochondrial outer membrane;0.000399282754533766!GO:0008250;oligosaccharyl transferase complex;0.00040593006050107!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000408007754896338!GO:0046519;sphingoid metabolic process;0.000427492713240645!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000455332390627758!GO:0000428;DNA-directed RNA polymerase complex;0.000455332390627758!GO:0045045;secretory pathway;0.000476316016713383!GO:0046483;heterocycle metabolic process;0.000497601567279774!GO:0003729;mRNA binding;0.000518328944437929!GO:0004576;oligosaccharyl transferase activity;0.000520900503457075!GO:0006606;protein import into nucleus;0.000546893978856816!GO:0006612;protein targeting to membrane;0.000622120317854529!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000642947467374298!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000645682109503722!GO:0022890;inorganic cation transmembrane transporter activity;0.00065432410666536!GO:0051920;peroxiredoxin activity;0.000659538174805925!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000748790084385112!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000754640172330145!GO:0008610;lipid biosynthetic process;0.000787879064316369!GO:0005048;signal sequence binding;0.000883976300167255!GO:0016481;negative regulation of transcription;0.000889820110347345!GO:0018196;peptidyl-asparagine modification;0.000905945634919763!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.000905945634919763!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000964598555439771!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000964598555439771!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000964598555439771!GO:0043284;biopolymer biosynthetic process;0.00101325571871241!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00103803439018712!GO:0006497;protein amino acid lipidation;0.00104712064191308!GO:0005885;Arp2/3 protein complex;0.00105194601047023!GO:0006506;GPI anchor biosynthetic process;0.00105194601047023!GO:0000049;tRNA binding;0.00106254699165611!GO:0032561;guanyl ribonucleotide binding;0.00110048566478359!GO:0019001;guanyl nucleotide binding;0.00110048566478359!GO:0006334;nucleosome assembly;0.00117000140811981!GO:0051789;response to protein stimulus;0.00124047600695735!GO:0006986;response to unfolded protein;0.00124047600695735!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00124584662653284!GO:0006505;GPI anchor metabolic process;0.00125630197099715!GO:0006118;electron transport;0.00131288951521592!GO:0008186;RNA-dependent ATPase activity;0.00131732317641894!GO:0048037;cofactor binding;0.00132442684706064!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00133871381134052!GO:0006818;hydrogen transport;0.00135311238782326!GO:0051168;nuclear export;0.00137435711138546!GO:0030384;phosphoinositide metabolic process;0.00142988949998687!GO:0030176;integral to endoplasmic reticulum membrane;0.00145017104652237!GO:0006650;glycerophospholipid metabolic process;0.00146939634877685!GO:0015992;proton transport;0.00167208956644601!GO:0051301;cell division;0.00167903185094914!GO:0006401;RNA catabolic process;0.00178824841076296!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0017958855230475!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0017958855230475!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00194904652953815!GO:0006520;amino acid metabolic process;0.00197084570474462!GO:0045941;positive regulation of transcription;0.00197084570474462!GO:0000096;sulfur amino acid metabolic process;0.00200247796464119!GO:0006261;DNA-dependent DNA replication;0.00204752122799621!GO:0031497;chromatin assembly;0.00209216637310805!GO:0016272;prefoldin complex;0.00213103448422259!GO:0031252;leading edge;0.00213295613817471!GO:0051287;NAD binding;0.0021755113788904!GO:0008361;regulation of cell size;0.00220757160421587!GO:0006891;intra-Golgi vesicle-mediated transport;0.00229904945149301!GO:0007040;lysosome organization and biogenesis;0.00231808931417589!GO:0048500;signal recognition particle;0.00235211891520569!GO:0016363;nuclear matrix;0.00237875228994419!GO:0031970;organelle envelope lumen;0.00247373081831182!GO:0030663;COPI coated vesicle membrane;0.00248163500501694!GO:0030126;COPI vesicle coat;0.00248163500501694!GO:0016044;membrane organization and biogenesis;0.00266346426555894!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00266346426555894!GO:0015002;heme-copper terminal oxidase activity;0.00266346426555894!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00266346426555894!GO:0004129;cytochrome-c oxidase activity;0.00266346426555894!GO:0006402;mRNA catabolic process;0.00270768366553948!GO:0045786;negative regulation of progression through cell cycle;0.00279273370797276!GO:0045893;positive regulation of transcription, DNA-dependent;0.00279273370797276!GO:0001558;regulation of cell growth;0.0028350704176768!GO:0051087;chaperone binding;0.00284093682039183!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00284099158385494!GO:0003690;double-stranded DNA binding;0.00286477344534489!GO:0006767;water-soluble vitamin metabolic process;0.00306935576560157!GO:0004004;ATP-dependent RNA helicase activity;0.00323478643291704!GO:0008168;methyltransferase activity;0.00345401393530541!GO:0042158;lipoprotein biosynthetic process;0.00364963352641368!GO:0008632;apoptotic program;0.00376745146970619!GO:0000059;protein import into nucleus, docking;0.0038638940955692!GO:0009116;nucleoside metabolic process;0.0038638940955692!GO:0008312;7S RNA binding;0.0038638940955692!GO:0016741;transferase activity, transferring one-carbon groups;0.0039296651458099!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00394132974016872!GO:0051252;regulation of RNA metabolic process;0.00399542601041359!GO:0005684;U2-dependent spliceosome;0.00402777643842172!GO:0006352;transcription initiation;0.00413753465745695!GO:0016049;cell growth;0.00427625649795316!GO:0007243;protein kinase cascade;0.00453941952469319!GO:0006007;glucose catabolic process;0.00463625971373382!GO:0050794;regulation of cellular process;0.00463625971373382!GO:0031072;heat shock protein binding;0.00464330779732608!GO:0003684;damaged DNA binding;0.00465823148031602!GO:0009451;RNA modification;0.00467560225210319!GO:0006643;membrane lipid metabolic process;0.00469032794900653!GO:0042802;identical protein binding;0.00469032794900653!GO:0022406;membrane docking;0.0052856065522566!GO:0048278;vesicle docking;0.0052856065522566!GO:0003746;translation elongation factor activity;0.00529727334931507!GO:0048522;positive regulation of cellular process;0.00553217730851769!GO:0019318;hexose metabolic process;0.00579750282991136!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00583774634210868!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.00587327480213333!GO:0000279;M phase;0.00597081936786462!GO:0005996;monosaccharide metabolic process;0.00600769218632099!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00601137412170006!GO:0045047;protein targeting to ER;0.00601137412170006!GO:0005637;nuclear inner membrane;0.0060173703432555!GO:0000287;magnesium ion binding;0.00604626226797627!GO:0006807;nitrogen compound metabolic process;0.0060478424899903!GO:0005905;coated pit;0.00623021506020001!GO:0006749;glutathione metabolic process;0.0062732628268884!GO:0006740;NADPH regeneration;0.00633493514248367!GO:0006098;pentose-phosphate shunt;0.00633493514248367!GO:0048487;beta-tubulin binding;0.00634816639010094!GO:0030137;COPI-coated vesicle;0.00643250103075793!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.00644007292664367!GO:0030133;transport vesicle;0.00645512894644024!GO:0006595;polyamine metabolic process;0.00648536506361968!GO:0008180;signalosome;0.00649682445943419!GO:0006733;oxidoreduction coenzyme metabolic process;0.00659952745592137!GO:0007033;vacuole organization and biogenesis;0.00667990778725556!GO:0006904;vesicle docking during exocytosis;0.00669288447096674!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00681551359823803!GO:0019899;enzyme binding;0.00684167342339532!GO:0031902;late endosome membrane;0.00684167342339532!GO:0006289;nucleotide-excision repair;0.00691349298598115!GO:0006778;porphyrin metabolic process;0.00737256226448057!GO:0033013;tetrapyrrole metabolic process;0.00737256226448057!GO:0051539;4 iron, 4 sulfur cluster binding;0.00742716238057795!GO:0016251;general RNA polymerase II transcription factor activity;0.00750768878613146!GO:0030658;transport vesicle membrane;0.00757632914963577!GO:0043022;ribosome binding;0.00761423396279759!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00761529198222245!GO:0005758;mitochondrial intermembrane space;0.00761529198222245!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00765525483779443!GO:0008139;nuclear localization sequence binding;0.00773157467865234!GO:0043488;regulation of mRNA stability;0.00779387174743472!GO:0043487;regulation of RNA stability;0.00779387174743472!GO:0006081;aldehyde metabolic process;0.00779440058367085!GO:0051540;metal cluster binding;0.00794499087286409!GO:0051536;iron-sulfur cluster binding;0.00794499087286409!GO:0009303;rRNA transcription;0.00824420867309767!GO:0005869;dynactin complex;0.00839964837800584!GO:0015631;tubulin binding;0.008458828051814!GO:0051329;interphase of mitotic cell cycle;0.00847790519198987!GO:0006509;membrane protein ectodomain proteolysis;0.00882604798803696!GO:0033619;membrane protein proteolysis;0.00882604798803696!GO:0030134;ER to Golgi transport vesicle;0.00884160400543563!GO:0008637;apoptotic mitochondrial changes;0.00888766313222427!GO:0035258;steroid hormone receptor binding;0.00893221971875087!GO:0044255;cellular lipid metabolic process;0.00913361252009994!GO:0006302;double-strand break repair;0.00931255664212761!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.00931255664212761!GO:0006611;protein export from nucleus;0.0100866099426009!GO:0004518;nuclease activity;0.0100963024510426!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0101561124580011!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0101661155480689!GO:0006769;nicotinamide metabolic process;0.0103611112817062!GO:0006519;amino acid and derivative metabolic process;0.0103898707752276!GO:0016126;sterol biosynthetic process;0.0103999073713581!GO:0009308;amine metabolic process;0.0107288482534063!GO:0004527;exonuclease activity;0.0107969542444164!GO:0005975;carbohydrate metabolic process;0.0108192962916091!GO:0033367;protein localization in mast cell secretory granule;0.010900304201559!GO:0033365;protein localization in organelle;0.010900304201559!GO:0033371;T cell secretory granule organization and biogenesis;0.010900304201559!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.010900304201559!GO:0033375;protease localization in T cell secretory granule;0.010900304201559!GO:0042629;mast cell granule;0.010900304201559!GO:0033377;maintenance of protein localization in T cell secretory granule;0.010900304201559!GO:0033364;mast cell secretory granule organization and biogenesis;0.010900304201559!GO:0033380;granzyme B localization in T cell secretory granule;0.010900304201559!GO:0033379;maintenance of protease localization in T cell secretory granule;0.010900304201559!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.010900304201559!GO:0033368;protease localization in mast cell secretory granule;0.010900304201559!GO:0033366;protein localization in secretory granule;0.010900304201559!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.010900304201559!GO:0033374;protein localization in T cell secretory granule;0.010900304201559!GO:0032940;secretion by cell;0.0109441405838928!GO:0005832;chaperonin-containing T-complex;0.0111106093960456!GO:0004532;exoribonuclease activity;0.0117245836443359!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0117245836443359!GO:0019377;glycolipid catabolic process;0.0118389308708777!GO:0006695;cholesterol biosynthetic process;0.0119132643446644!GO:0005819;spindle;0.011949243838882!GO:0008652;amino acid biosynthetic process;0.0121791579151267!GO:0016788;hydrolase activity, acting on ester bonds;0.0122548095252011!GO:0046983;protein dimerization activity;0.0122576952708908!GO:0003711;transcription elongation regulator activity;0.0122847214418096!GO:0006284;base-excision repair;0.0123483023254186!GO:0030659;cytoplasmic vesicle membrane;0.0125871267447707!GO:0030036;actin cytoskeleton organization and biogenesis;0.0128528634258127!GO:0007034;vacuolar transport;0.0132046470312572!GO:0048468;cell development;0.0133470618190559!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0139440203097395!GO:0030145;manganese ion binding;0.0143724898437861!GO:0005791;rough endoplasmic reticulum;0.014585806871468!GO:0015036;disulfide oxidoreductase activity;0.0146648270500332!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0149830100756002!GO:0010257;NADH dehydrogenase complex assembly;0.0149830100756002!GO:0033108;mitochondrial respiratory chain complex assembly;0.0149830100756002!GO:0030521;androgen receptor signaling pathway;0.0151937799144407!GO:0030127;COPII vesicle coat;0.0152016066167349!GO:0012507;ER to Golgi transport vesicle membrane;0.0152016066167349!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0153478418748026!GO:0006400;tRNA modification;0.0155031465272421!GO:0006739;NADP metabolic process;0.0159166224578019!GO:0006779;porphyrin biosynthetic process;0.0164376825969189!GO:0033014;tetrapyrrole biosynthetic process;0.0164376825969189!GO:0006516;glycoprotein catabolic process;0.0167141199183742!GO:0031418;L-ascorbic acid binding;0.0168106646058954!GO:0006066;alcohol metabolic process;0.0169940642529827!GO:0031124;mRNA 3'-end processing;0.0172268226060036!GO:0006144;purine base metabolic process;0.0174349912452018!GO:0031543;peptidyl-proline dioxygenase activity;0.0176615179836928!GO:0045892;negative regulation of transcription, DNA-dependent;0.0176667411156848!GO:0040008;regulation of growth;0.0177319301756479!GO:0000339;RNA cap binding;0.0182010189199314!GO:0030660;Golgi-associated vesicle membrane;0.0182342602774205!GO:0044433;cytoplasmic vesicle part;0.0182342602774205!GO:0006541;glutamine metabolic process;0.0184604538955291!GO:0051325;interphase;0.0192380748273821!GO:0012506;vesicle membrane;0.0192380748273821!GO:0005774;vacuolar membrane;0.0193770871462272!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0196635397537777!GO:0045039;protein import into mitochondrial inner membrane;0.0196635397537777!GO:0065009;regulation of a molecular function;0.0200978581229547!GO:0016197;endosome transport;0.020767802623648!GO:0006417;regulation of translation;0.0209238938591054!GO:0016791;phosphoric monoester hydrolase activity;0.0211383750658859!GO:0008629;induction of apoptosis by intracellular signals;0.0219890413572233!GO:0004185;serine carboxypeptidase activity;0.0224811974216224!GO:0006220;pyrimidine nucleotide metabolic process;0.0224811974216224!GO:0006665;sphingolipid metabolic process;0.0226384386844259!GO:0003955;NAD(P)H dehydrogenase (quinone) activity;0.0228395603614854!GO:0008234;cysteine-type peptidase activity;0.0231675350745562!GO:0007010;cytoskeleton organization and biogenesis;0.0237019551244848!GO:0031301;integral to organelle membrane;0.0242688176672455!GO:0007264;small GTPase mediated signal transduction;0.0242861184050532!GO:0042168;heme metabolic process;0.0246241021146084!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0246762272074718!GO:0051052;regulation of DNA metabolic process;0.0248245139251338!GO:0006629;lipid metabolic process;0.0251472979677492!GO:0003756;protein disulfide isomerase activity;0.0254937967253347!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0254937967253347!GO:0004029;aldehyde dehydrogenase (NAD) activity;0.0255429149124263!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0258125259217473!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0258125259217473!GO:0006006;glucose metabolic process;0.0259288219270207!GO:0008538;proteasome activator activity;0.025946699333637!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0260778154385038!GO:0050811;GABA receptor binding;0.0270475254687217!GO:0035035;histone acetyltransferase binding;0.0273152503452204!GO:0047115;trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity;0.0275132737303064!GO:0000097;sulfur amino acid biosynthetic process;0.0279323883598159!GO:0030508;thiol-disulfide exchange intermediate activity;0.0279440961928408!GO:0030132;clathrin coat of coated pit;0.0283035450857682!GO:0016407;acetyltransferase activity;0.0284912986038863!GO:0006378;mRNA polyadenylation;0.0288724444600547!GO:0000738;DNA catabolic process, exonucleolytic;0.0292596933401871!GO:0022411;cellular component disassembly;0.0295178479868169!GO:0006376;mRNA splice site selection;0.0301864136735097!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0301864136735097!GO:0008408;3'-5' exonuclease activity;0.0302750137858414!GO:0046128;purine ribonucleoside metabolic process;0.0302897735263547!GO:0042278;purine nucleoside metabolic process;0.0302897735263547!GO:0019798;procollagen-proline dioxygenase activity;0.0303111149322944!GO:0004563;beta-N-acetylhexosaminidase activity;0.0305563328864992!GO:0046982;protein heterodimerization activity;0.0307001934962848!GO:0009112;nucleobase metabolic process;0.0309088568927932!GO:0006458;'de novo' protein folding;0.0309088568927932!GO:0051084;'de novo' posttranslational protein folding;0.0309088568927932!GO:0007041;lysosomal transport;0.0310391715920989!GO:0019222;regulation of metabolic process;0.0311924507278673!GO:0030032;lamellipodium biogenesis;0.0313334138919524!GO:0006644;phospholipid metabolic process;0.0315423117387668!GO:0003678;DNA helicase activity;0.032215051557256!GO:0008017;microtubule binding;0.0324635439262752!GO:0005669;transcription factor TFIID complex;0.0328631549471251!GO:0030027;lamellipodium;0.0332976214078763!GO:0007021;tubulin folding;0.033364749091989!GO:0044438;microbody part;0.0335045086003502!GO:0044439;peroxisomal part;0.0335045086003502!GO:0030118;clathrin coat;0.0336487627313084!GO:0006308;DNA catabolic process;0.0337122003629079!GO:0017166;vinculin binding;0.0341052285299649!GO:0000030;mannosyltransferase activity;0.0349446410352025!GO:0016408;C-acyltransferase activity;0.0349762857112578!GO:0030433;ER-associated protein catabolic process;0.0360939395810473!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0360939395810473!GO:0031326;regulation of cellular biosynthetic process;0.0366782470795953!GO:0003702;RNA polymerase II transcription factor activity;0.0368306989534256!GO:0030149;sphingolipid catabolic process;0.0372410493972!GO:0046365;monosaccharide catabolic process;0.0374690661699199!GO:0007220;Notch receptor processing;0.0378985849696586!GO:0016790;thiolester hydrolase activity;0.0379279120304796!GO:0019362;pyridine nucleotide metabolic process;0.0380060499679861!GO:0000209;protein polyubiquitination;0.0380060499679861!GO:0051101;regulation of DNA binding;0.0380410782209177!GO:0050681;androgen receptor binding;0.0381319429652846!GO:0044437;vacuolar part;0.0397156140616092!GO:0005784;translocon complex;0.0400680448761676!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0401049148031522!GO:0046479;glycosphingolipid catabolic process;0.0402653603887685!GO:0008320;protein transmembrane transporter activity;0.040441428047553!GO:0031371;ubiquitin conjugating enzyme complex;0.040781925118313!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.040781925118313!GO:0032984;macromolecular complex disassembly;0.0423853742595413!GO:0030911;TPR domain binding;0.0427672478221099!GO:0004177;aminopeptidase activity;0.0433800079225441!GO:0031123;RNA 3'-end processing;0.0434047028575933!GO:0051098;regulation of binding;0.0438989731401716!GO:0006405;RNA export from nucleus;0.0444086518069453!GO:0030518;steroid hormone receptor signaling pathway;0.0447325872438024!GO:0001836;release of cytochrome c from mitochondria;0.0449863773978761!GO:0022884;macromolecule transmembrane transporter activity;0.0456924683974263!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0456924683974263!GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors;0.045912391770085!GO:0016584;nucleosome positioning;0.0463015911969962!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0463016019539781!GO:0043624;cellular protein complex disassembly;0.0463080509694185!GO:0043189;H4/H2A histone acetyltransferase complex;0.0463121430844601!GO:0006892;post-Golgi vesicle-mediated transport;0.0464456511026468!GO:0000175;3'-5'-exoribonuclease activity;0.046494022691017!GO:0007051;spindle organization and biogenesis;0.046733381506378!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0469766634129047!GO:0000786;nucleosome;0.0473592971270632!GO:0031625;ubiquitin protein ligase binding;0.0484027732753018!GO:0005777;peroxisome;0.0484027732753018!GO:0042579;microbody;0.0484027732753018!GO:0006635;fatty acid beta-oxidation;0.0485713245225918!GO:0000178;exosome (RNase complex);0.0485807552497108!GO:0008097;5S rRNA binding;0.0492380332632152!GO:0031903;microbody membrane;0.0492406689805259!GO:0005778;peroxisomal membrane;0.0492406689805259!GO:0043130;ubiquitin binding;0.0492406689805259!GO:0032182;small conjugating protein binding;0.0492406689805259!GO:0030503;regulation of cell redox homeostasis;0.0494642628992664!GO:0007017;microtubule-based process;0.0495157044914182!GO:0031628;opioid receptor binding;0.0497127307082058!GO:0031852;mu-type opioid receptor binding;0.0497127307082058!GO:0042769;DNA damage response, detection of DNA damage;0.0497499803153944!GO:0007050;cell cycle arrest;0.0497508183118429!GO:0051085;chaperone cofactor-dependent protein folding;0.0499582309845291 | |||
|sample_id=10839 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=lung | |||
|top_motifs=NKX2-1,4:2.09369794104;ESRRA:2.03807310441;FOXQ1:1.59481193041;HIF1A:1.4460618521;AIRE:1.39701708854;POU6F1:1.33463468094;NKX3-1:1.32015622666;TBX4,5:1.3163376972;ONECUT1,2:1.17006887559;NR6A1:1.06871152916;NFE2L2:1.06670421059;FOXN1:1.04622564363;bHLH_family:1.02328450129;ZBTB16:0.995633913082;FOX{I1,J2}:0.978945578629;HES1:0.886150713386;CEBPA,B_DDIT3:0.826141932804;ELK1,4_GABP{A,B1}:0.802887306066;PAX1,9:0.796245880357;EN1,2:0.790249568485;AHR_ARNT_ARNT2:0.788137354385;RORA:0.783322156331;HOX{A6,A7,B6,B7}:0.781184828413;PPARG:0.738558859518;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.728970839904;ALX4:0.717164967205;YY1:0.716405997694;ATF5_CREB3:0.705943900482;FOXL1:0.66312140744;MYOD1:0.663116404813;UFEwm:0.627097545066;CDX1,2,4:0.626989087924;HOXA9_MEIS1:0.600710430794;PAX4:0.581164612151;ARID5B:0.577796375327;FOX{F1,F2,J1}:0.573238617026;VSX1,2:0.572902544751;CREB1:0.567095321349;EVI1:0.55465890513;LMO2:0.548919336562;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.546548664768;NFE2L1:0.527005158915;NFE2:0.509322211255;STAT5{A,B}:0.418328529409;BREu{core}:0.397917821794;ATF4:0.382256492533;ATF2:0.348340178665;IKZF1:0.336254352364;DBP:0.326135254395;LEF1_TCF7_TCF7L1,2:0.3249225343;FOXP3:0.323088990905;PAX8:0.31965268253;GFI1B:0.314146137331;ESR1:0.291647305484;POU5F1:0.291438697716;RXR{A,B,G}:0.261114947848;PRRX1,2:0.23756764795;TFAP2B:0.216571664932;RBPJ:0.209282562742;LHX3,4:0.20365029019;PAX6:0.152638627757;POU2F1..3:0.141045895558;HIC1:0.109227778133;HOX{A4,D4}:0.102138080279;NRF1:0.0908676175049;RFX1:0.0757332826692;TLX1..3_NFIC{dimer}:0.0593483672097;PBX1:0.0586981578239;NKX6-1,2:0.0581773071365;MAFB:0.0469851393333;ZNF423:0.0431773662078;EP300:0.0369165168361;XBP1:0.0274054271674;FOXD3:0.0193794156951;ADNP_IRX_SIX_ZHX:0.015451445282;TFCP2:-0.0299529339555;ZFP161:-0.0407389625484;HNF4A_NR2F1,2:-0.050011974122;PDX1:-0.0516969669718;MED-1{core}:-0.0625649397271;CRX:-0.0643781334694;FOX{D1,D2}:-0.0711590278129;FOSL2:-0.071628860648;ELF1,2,4:-0.0803730791336;BACH2:-0.0902135720058;EBF1:-0.094343516659;TP53:-0.101002275774;HLF:-0.120519183761;RFX2..5_RFXANK_RFXAP:-0.128268029613;NKX3-2:-0.133482403622;GLI1..3:-0.134165879804;BPTF:-0.136180560121;PAX5:-0.160990855162;PATZ1:-0.16894034933;SNAI1..3:-0.181059723908;ZEB1:-0.191771974171;IKZF2:-0.194333700113;NKX2-2,8:-0.195137556647;ATF6:-0.19718707102;MYBL2:-0.200866833571;CDC5L:-0.203024544026;ZNF143:-0.204507777577;HOX{A5,B5}:-0.208653859875;HNF1A:-0.211492603554;TBP:-0.21168162062;NR1H4:-0.214565347501;GATA6:-0.25623732861;T:-0.275533782;FOS_FOS{B,L1}_JUN{B,D}:-0.295306205053;PITX1..3:-0.296198455864;ZBTB6:-0.304153887747;SOX2:-0.305598905354;JUN:-0.313296275361;MYB:-0.334678881451;NANOG:-0.339398511336;TOPORS:-0.340362107075;MEF2{A,B,C,D}:-0.341151892466;REST:-0.344621734464;TFAP2{A,C}:-0.357562762493;STAT2,4,6:-0.357718424528;FOXA2:-0.368194855953;HMGA1,2:-0.370395724072;SREBF1,2:-0.37169498503;NFIL3:-0.378420152882;TEF:-0.386269388054;MYFfamily:-0.397307830906;NHLH1,2:-0.406274953439;E2F1..5:-0.426306187931;NFKB1_REL_RELA:-0.426724861307;ALX1:-0.435279576963;PAX2:-0.443582715521;TEAD1:-0.463994510242;TAL1_TCF{3,4,12}:-0.469578851748;SOX5:-0.483222637558;FOXM1:-0.485700895293;ETS1,2:-0.486866645381;FOXP1:-0.491595063659;EGR1..3:-0.49498097009;KLF4:-0.503993573195;TFDP1:-0.5245883109;NANOG{mouse}:-0.52602557743;IRF7:-0.526162760532;NR5A1,2:-0.527312597938;POU3F1..4:-0.530446197779;NFIX:-0.540735205735;POU1F1:-0.569212340788;GTF2I:-0.569471576911;DMAP1_NCOR{1,2}_SMARC:-0.58180565196;SPI1:-0.594645180758;ZNF148:-0.600589869906;SPIB:-0.620123530618;PRDM1:-0.632705905704;GTF2A1,2:-0.645262681583;SP1:-0.657258704865;NFY{A,B,C}:-0.657418089591;HAND1,2:-0.659083521812;FOXO1,3,4:-0.664476378083;SOX{8,9,10}:-0.685480361273;GFI1:-0.711623335458;IRF1,2:-0.721143513853;TFAP4:-0.727001348799;CUX2:-0.7303559605;RXRA_VDR{dimer}:-0.749435222025;ZIC1..3:-0.795879501234;AR:-0.798282580835;OCT4_SOX2{dimer}:-0.808284750479;NKX2-3_NKX2-5:-0.824430423904;RUNX1..3:-0.83660941281;SOX17:-0.844803784877;MTF1:-0.851777214994;XCPE1{core}:-0.861497425973;GATA4:-0.873171356942;NFATC1..3:-0.886000194119;RREB1:-0.887322750692;ZNF238:-0.912233172967;SRF:-0.961716027297;NR3C1:-0.989669731572;HMX1:-0.996628021016;MZF1:-1.04103667792;HSF1,2:-1.12913184725;TLX2:-1.14360999397;STAT1,3:-1.15710705382;MAZ:-1.19131857482;PAX3,7:-1.19571322344;GZF1:-1.2356585472;TGIF1:-1.24260359839;MTE{core}:-1.49981876862;ZNF384:-1.52404585619;SPZ1:-1.53576469279;GCM1,2:-1.5532222913;SMAD1..7,9:-1.69457713177;HBP1_HMGB_SSRP1_UBTF:-2.67102068712 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10839-111E2;search_select_hide=table117:FF:10839-111E2 | |||
}} | }} |
Latest revision as of 15:08, 3 June 2020
Name: | large cell lung carcinoma cell line:NCI-H460 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs12806 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12806
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12806
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.417 |
10 | 10 | 0.235 |
100 | 100 | 0.00284 |
101 | 101 | 0.29 |
102 | 102 | 0.295 |
103 | 103 | 0.725 |
104 | 104 | 0.825 |
105 | 105 | 0.00874 |
106 | 106 | 0.13 |
107 | 107 | 0.54 |
108 | 108 | 0.122 |
109 | 109 | 0.0692 |
11 | 11 | 0.911 |
110 | 110 | 0.752 |
111 | 111 | 0.809 |
112 | 112 | 0.662 |
113 | 113 | 0.018 |
114 | 114 | 0.609 |
115 | 115 | 0.684 |
116 | 116 | 0.248 |
117 | 117 | 0.902 |
118 | 118 | 0.0186 |
119 | 119 | 0.636 |
12 | 12 | 0.39 |
120 | 120 | 0.0173 |
121 | 121 | 0.00755 |
122 | 122 | 0.975 |
123 | 123 | 0.831 |
124 | 124 | 0.173 |
125 | 125 | 0.785 |
126 | 126 | 0.711 |
127 | 127 | 0.932 |
128 | 128 | 0.507 |
129 | 129 | 0.735 |
13 | 13 | 0.302 |
130 | 130 | 0.557 |
131 | 131 | 0.466 |
132 | 132 | 0.389 |
133 | 133 | 0.37 |
134 | 134 | 0.187 |
135 | 135 | 0.27 |
136 | 136 | 0.0544 |
137 | 137 | 0.0685 |
138 | 138 | 0.939 |
139 | 139 | 0.308 |
14 | 14 | 0.356 |
140 | 140 | 0.65 |
141 | 141 | 0.249 |
142 | 142 | 0.103 |
143 | 143 | 0.114 |
144 | 144 | 0.251 |
145 | 145 | 0.0267 |
146 | 146 | 0.864 |
147 | 147 | 0.123 |
148 | 148 | 0.168 |
149 | 149 | 0.888 |
15 | 15 | 0.0414 |
150 | 150 | 0.829 |
151 | 151 | 0.244 |
152 | 152 | 0.201 |
153 | 153 | 0.927 |
154 | 154 | 0.788 |
155 | 155 | 0.418 |
156 | 156 | 0.633 |
157 | 157 | 0.668 |
158 | 158 | 0.311 |
159 | 159 | 0.152 |
16 | 16 | 0.886 |
160 | 160 | 0.701 |
161 | 161 | 0.448 |
162 | 162 | 0.859 |
163 | 163 | 0.94 |
164 | 164 | 0.0348 |
165 | 165 | 0.848 |
166 | 166 | 0.711 |
167 | 167 | 0.216 |
168 | 168 | 0.64 |
169 | 169 | 0.95 |
17 | 17 | 0.954 |
18 | 18 | 0.0503 |
19 | 19 | 0.456 |
2 | 2 | 0.116 |
20 | 20 | 0.115 |
21 | 21 | 0.994 |
22 | 22 | 0.441 |
23 | 23 | 0.0826 |
24 | 24 | 0.261 |
25 | 25 | 0.484 |
26 | 26 | 0.257 |
27 | 27 | 0.743 |
28 | 28 | 0.755 |
29 | 29 | 0.00138 |
3 | 3 | 0.759 |
30 | 30 | 0.133 |
31 | 31 | 0.668 |
32 | 32 | 0.0446 |
33 | 33 | 0.47 |
34 | 34 | 0.254 |
35 | 35 | 0.415 |
36 | 36 | 0.12 |
37 | 37 | 0.46 |
38 | 38 | 0.611 |
39 | 39 | 0.757 |
4 | 4 | 0.152 |
40 | 40 | 0.201 |
41 | 41 | 0.465 |
42 | 42 | 0.822 |
43 | 43 | 0.269 |
44 | 44 | 0.0323 |
45 | 45 | 0.27 |
46 | 46 | 0.669 |
47 | 47 | 0.885 |
48 | 48 | 0.783 |
49 | 49 | 0.081 |
5 | 5 | 0.468 |
50 | 50 | 0.824 |
51 | 51 | 0.703 |
52 | 52 | 0.216 |
53 | 53 | 0.0827 |
54 | 54 | 0.549 |
55 | 55 | 0.898 |
56 | 56 | 0.588 |
57 | 57 | 0.408 |
58 | 58 | 0.903 |
59 | 59 | 0.915 |
6 | 6 | 0.0327 |
60 | 60 | 0.201 |
61 | 61 | 0.385 |
62 | 62 | 0.959 |
63 | 63 | 0.731 |
64 | 64 | 0.989 |
65 | 65 | 0.34 |
66 | 66 | 0.349 |
67 | 67 | 0.484 |
68 | 68 | 0.624 |
69 | 69 | 0.585 |
7 | 7 | 0.646 |
70 | 70 | 0.654 |
71 | 71 | 0.45 |
72 | 72 | 0.175 |
73 | 73 | 0.921 |
74 | 74 | 0.458 |
75 | 75 | 0.212 |
76 | 76 | 0.0138 |
77 | 77 | 0.29 |
78 | 78 | 0.873 |
79 | 79 | 0.361 |
8 | 8 | 0.0662 |
80 | 80 | 0.0623 |
81 | 81 | 0.561 |
82 | 82 | 0.216 |
83 | 83 | 0.795 |
84 | 84 | 0.0773 |
85 | 85 | 0.559 |
86 | 86 | 0.967 |
87 | 87 | 0.277 |
88 | 88 | 0.663 |
89 | 89 | 0.89 |
9 | 9 | 0.0925 |
90 | 90 | 0.701 |
91 | 91 | 0.00446 |
92 | 92 | 0.842 |
93 | 93 | 0.414 |
94 | 94 | 0.698 |
95 | 95 | 0.00155 |
96 | 96 | 0.0666 |
97 | 97 | 0.767 |
98 | 98 | 0.213 |
99 | 99 | 0.733 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12806
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102207 NCI-H460 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000082 (epithelial cell of lung)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
0050615 (respiratory system cancer)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
1324 (lung cancer)
305 (carcinoma)
3905 (lung carcinoma)
3908 (non-small cell lung carcinoma)
4556 (lung large cell carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002048 (lung)
0002100 (trunk)
0000483 (epithelium)
0000479 (tissue)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000466 (immaterial anatomical entity)
0000062 (organ)
0004111 (anatomical conduit)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0004802 (respiratory tract epithelium)
0000025 (tube)
0005911 (endo-epithelium)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0009569 (subdivision of trunk)
0005178 (thoracic cavity element)
0000072 (segment of respiratory tract)
0005177 (trunk region element)
0004807 (respiratory system epithelium)
0000117 (respiratory tube)
0000171 (respiration organ)
0000115 (lung epithelium)
0000464 (anatomical space)
0005181 (thoracic segment organ)
0010317 (germ layer / neural crest derived structure)
0000065 (respiratory tract)
0000170 (pair of lungs)
0001004 (respiratory system)
0002224 (thoracic cavity)
0000915 (thoracic segment of trunk)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100297 (carcinoma cell line sample)
0100353 (lung cell line sample)
0101120 (epithelial cell line sample)
0100762 (lung cancer cell line sample)
0102205 (large cell lung cancer cell line sample)
0102207 (NCI-H460 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0001041 (foregut)
UBERON:0008947 (respiratory primordium)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)