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{{f5samples
{{f5samples
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|DRA_sample_Accession=CAGE@SAMD00005177
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000051,CL:0000063,CL:0000134,CL:0000144,CL:0000219,CL:0000255,CL:0000542,CL:0000548,CL:0000566,CL:0000623,CL:0000723,CL:0000738,CL:0000825,CL:0000837,CL:0000838,CL:0000988,CL:0002031,CL:0002032,CL:0002087,CL:0002320,CL:0002371
|DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005177
|accession_numbers=CAGE;DRX008371;DRR009243;DRZ000668;DRZ002053;DRZ012018;DRZ013403
|accession_numbers_RNASeq=sRNA-Seq;DRX037222;DRR041588;DRZ007230
|ancestors_in_anatomy_facet=
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000623
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000119
|comment=
|comment=
|created_by=
|created_by=
|creation_date=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|def=
|expression_enrichment_score=chr1:25256756..25256774,-!p1@RUNX3!2.50!572.71!RUNX3;;chr2:192015701..192015743,-!p1@STAT4!2.22!224.47!STAT4;;chr17:45810594..45810608,+!p1@TBX21!2.12!129.81!TBX21;;chr2:145271342..145271377,-!p5@ZEB2!2.08!119.24!ZEB2;;chr19:45971246..45971265,+!p1@FOSB!2.01!1748.31!FOSB;;chr2:157189180..157189290,-!p1@NR4A2!1.97!456.91!NR4A2;;chr20:50159198..50159299,-!p1@NFATC2!1.96!128.95!NFATC2;;chr6:391743..391759,+!p1@IRF4!1.86!71.37!IRF4;;chr9:117150254..117150271,-!p1@AKNA!1.84!178.76!AKNA;;chr7:50343634..50343717,+!p2@IKZF1!1.84!67.71!IKZF1;;chr10:8096631..8096660,+!p1@GATA3!1.83!80.64!GATA3;;chr6:106546808..106546833,+!p3@PRDM1!1.81!79.57!PRDM1;;chr15:60884706..60884743,-!p1@RORA!1.79!295.63!RORA;;chr19:54041669..54041697,+!p2@ZNF331!1.77!58.22!ZNF331;;chr9:102584262..102584276,+!p1@NR4A3!1.76!122.91!NR4A3;;chr17:38020392..38020477,-!p1@IKZF3!1.76!57.14!IKZF3;;chr14:75745523..75745537,+!p1@FOS!1.75!6186.14!FOS;;chr14:75746722..75746777,+!p2@FOS!1.74!68.14!FOS;;chr10:8096772..8096787,+!p2@GATA3!1.73!61.24!GATA3;;chr19:54058073..54058088,+!p1@ZNF331!1.73!53.26!ZNF331;;chr1:26697243..26697258,-!p1@ZNF683!1.72!51.53!ZNF683;;chr3:63953435..63953499,+!p1@ATXN7!1.70!49.59!ATXN7;;chr8:123793988..123794016,+!p1@ZHX2!1.68!80.86!ZHX2;;chr20:56195474..56195506,-!p1@ZBP1!1.68!46.79!ZBP1;;chr14:64971288..64971316,-!p2@ZBTB25!1.66!134.55!ZBTB25;;chrX:106960285..106960299,-!p1@TSC22D3!1.65!1115.87!TSC22D3;;chr12:72056800..72056834,+!p1@THAP2!1.64!56.49!THAP2;;chr2:192015677..192015691,-!p3@STAT4!1.64!42.91!STAT4;;chr3:39195075..39195088,-!p1@CSRNP1!1.61!237.19!CSRNP1;;chr1:59249688..59249703,-!p3@JUN!1.61!225.55!JUN;;chr9:3525727..3525828,-!p2@RFX3!1.59!94.66!RFX3;;chr2:231090433..231090469,+!p1@SP140!1.57!36.23!SP140;;chr5:133450365..133450444,+!p1@TCF7!1.56!153.74!TCF7;;chrX:106960180..106960197,-!p2@TSC22D3!1.54!123.34!TSC22D3;;chr19:16435625..16435682,+!p1@KLF2!1.51!951.35!KLF2;;chr2:192015750..192015793,-!p2@STAT4!1.51!41.83!STAT4;;chrY:21906594..21906622,-!p1@KDM5D!1.51!31.70!KDM5D;;chr3:5020939..5020952,+!p2@BHLHE40!1.50!94.44!BHLHE40;;chr10:35484053..35484076,+!p1@CREM!1.49!73.31!CREM;;chrX:106960221..106960236,-!p3@TSC22D3!1.47!76.33!TSC22D3;;chr9:102584128..102584144,+!p3@NR4A3!1.47!53.04!NR4A3;;chr4:57522166..57522260,-!p2@HOPX!1.46!31.70!HOPX;;chr5:133451294..133451310,+!p2@TCF7!1.46!27.82!TCF7;;chr14:35873947..35873965,-!p1@NFKBIA!1.45!1634.46!NFKBIA;;chr1:59249707..59249727,-!p1@JUN!1.45!1075.98!JUN;;chr10:3824332..3824425,-!p4@KLF6!1.45!43.77!KLF6;;chr6:106546834..106546850,+!p4@PRDM1!1.45!27.38!PRDM1;;chr1:26697189..26697205,-!p2@ZNF683!1.45!27.38!ZNF683;;chr4:103422499..103422632,+!p1@NFKB1!1.43!521.60!NFKB1;;chr5:131826457..131826514,-!p1@IRF1!1.42!937.33!IRF1;;chr14:35874077..35874091,-!p8@NFKBIA!1.42!25.23!NFKBIA;;chr2:145277640..145277771,-!p1@ZEB2!1.41!316.97!ZEB2;;chr3:23986824..23986848,+!p2@NR1D2!1.41!132.61!NR1D2;;chr9:102584241..102584261,+!p4@NR4A3!1.41!37.73!NR4A3;;chr1:151030536..151030549,+!p8@MLLT11!1.40!24.37!MLLT11;;chr16:85932760..85932775,+!p1@IRF8!1.40!23.93!IRF8;;chr6:91006518..91006570,-!p1@BACH2!1.39!52.61!BACH2;;chr8:81397820..81397836,+!p2@ZBTB10!1.39!29.54!ZBTB10;;chr17:37934365..37934387,-!p2@IKZF3!1.39!23.72!IKZF3;;chr2:61108878..61108891,+!p5@REL!1.38!23.07!REL;;chr2:231090471..231090504,+!p2@SP140!1.38!22.86!SP140;;chr2:208394817..208394834,+!p3@CREB1!1.35!84.53!CREB1;;chr19:19729477..19729542,-!p1@PBX4!1.35!45.50!PBX4;;chr8:67525443..67525459,-!p2@MYBL1!1.34!30.83!MYBL1;;chr18:46475696..46475713,-!p1@SMAD7!1.34!23.50!SMAD7;;chr7:104654690..104654704,+!p2@MLL5!1.33!40.32!MLL5;;chr7:104654718..104654741,+!p3@MLL5!1.33!29.54!MLL5;;chr1:25291475..25291511,-!p2@RUNX3!1.33!20.48!RUNX3;;chr7:50343895..50343936,+!p5@IKZF1!1.32!19.84!IKZF1;;chr14:35872453..35872485,-!p2@NFKBIA!1.31!47.65!NFKBIA;;chr13:74707894..74707947,-!p6@KLF12!1.31!21.56!KLF12;;chr2:68592406..68592424,+!p1@PLEK!1.31!19.41!PLEK;;chr8:60031619..60031676,-!p1@TOX!1.30!40.54!TOX;;chr8:81397876..81397898,+!p5@ZBTB10!1.30!22.43!ZBTB10;;chr8:123793252..123793266,+!p10@ZHX2!1.30!18.76!ZHX2;;chr2:61108695..61108753,+!p1@REL!1.29!123.99!REL;;chr8:81397846..81397860,+!p3@ZBTB10!1.29!23.07!ZBTB10;;chr19:54041645..54041661,+!p5@ZNF331!1.29!18.33!ZNF331;;chr3:18486354..18486377,-!p2@SATB1!1.28!22.43!SATB1;;chr11:67007548..67007610,+!p3@KDM2A!1.27!127.65!KDM2A;;chr1:10754477..10754517,-!p1@CASZ1!1.27!29.33!CASZ1;;chr12:72056773..72056796,+!p3@THAP2!1.27!23.07!THAP2;;chr6:106546786..106546802,+!p6@PRDM1!1.27!17.47!PRDM1;;chr19:12902289..12902307,+!p1@JUNB!1.26!3836.88!JUNB;;chr21:36421347..36421380,-!p8@RUNX1!1.25!16.82!RUNX1;;chr2:157189617..157189667,-!p4@NR4A2!1.25!16.60!NR4A2;;chr4:57522674..57522699,-!p5@HOPX!1.25!16.60!HOPX;;chr2:43453734..43453751,-!p1@ZFP36L2!1.24!1701.30!ZFP36L2;;chr3:39195037..39195069,-!p2@CSRNP1!1.24!98.97!CSRNP1;;chr10:35416142..35416169,+!p3@CREM!1.24!42.91!CREM;;chr17:38497662..38497713,+!p4@RARA!1.24!18.98!RARA;;chr1:59249645..59249656,-!p4@JUN!1.23!40.11!JUN;;chr2:97202480..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|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000623;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988
|ffid_belonging_in_development=CL:0000134,CL:0000051
|fonse_cell_line=
|fonse_cell_line=
|fonse_cell_line_closure=
|fonse_cell_line_closure=
Line 35: Line 44:
|fonse_treatment_closure=
|fonse_treatment_closure=
|has_quality=
|has_quality=
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor2.CNhs11957.11311-117C6.hg19.nobarcode.bam
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor2.CNhs11957.11311-117C6.hg19.ctss.bed.gz
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor2.CNhs11957.11311-117C6.hg19.nobarcode.rdna.fa.gz
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor2.CNhs11957.11311-117C6.hg38.nobarcode.bam
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Natural%2520Killer%2520Cells%252c%2520donor2.CNhs11957.11311-117C6.hg38.nobarcode.ctss.bed.gz
|id=FF:11311-117C6
|id=FF:11311-117C6
|is_a=EFO:0002091;;FF:0000002;;FF:0000119;;FF:0000210
|is_a=EFO:0002091;;FF:0000119
|is_obsolete=
|library_id=CNhs11957
|library_id_phase_based=2:CNhs11957
|microRNAs=
|microRNAs_nn=
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11311
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10013.GTTTCG.11311
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11311
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10013.GTTTCG.11311
|name=Natural Killer Cells, donor2
|name=Natural Killer Cells, donor2
|namespace=FANTOM5
|namespace=FANTOM5
Line 42: Line 65:
|profile_cagescan=,,,
|profile_cagescan=,,,
|profile_hcage=CNhs11957,LSID836,release011,COMPLETED
|profile_hcage=CNhs11957,LSID836,release011,COMPLETED
|profile_rnaseq=,,,
|profile_rnaseq=
|profile_srnaseq=SRhi10013,,,
|profile_srnaseq=SRhi10013,,,
|refex=http://refex.dbcls.jp/genelist.php?lang
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|rna_box=117
|rna_box=117
|rna_catalog_number=3H100-50-10
|rna_catalog_number=3H100-50-10
Line 56: Line 82:
|rna_tube_id=117C6
|rna_tube_id=117C6
|rna_weight_ug=10
|rna_weight_ug=10
|rnaseq_library_id=SRhi10013.GTTTCG
|sample_age=57
|sample_age=57
|sample_category=primary cells
|sample_cell_catalog=N/A
|sample_cell_catalog=N/A
|sample_cell_line=
|sample_cell_line=
Line 69: Line 97:
|sample_ethnicity=C
|sample_ethnicity=C
|sample_experimental_condition=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.10496954912315e-219!GO:0043227;membrane-bound organelle;1.0615450925788e-194!GO:0043231;intracellular membrane-bound organelle;2.07408562544708e-194!GO:0043226;organelle;5.76200685288792e-184!GO:0043229;intracellular organelle;2.76072973823236e-183!GO:0005737;cytoplasm;3.14327457505448e-121!GO:0005634;nucleus;1.54729167205073e-117!GO:0043170;macromolecule metabolic process;2.18482074301475e-105!GO:0044422;organelle part;8.39202822744538e-105!GO:0044446;intracellular organelle part;3.54966166246968e-103!GO:0044237;cellular metabolic process;6.79058063192665e-97!GO:0044238;primary metabolic process;2.93784807922207e-95!GO:0043283;biopolymer metabolic process;2.63373542804244e-81!GO:0032991;macromolecular complex;7.94158359916471e-81!GO:0044428;nuclear part;5.09011035790303e-79!GO:0044444;cytoplasmic part;5.55024496414155e-76!GO:0003723;RNA binding;4.43281650005219e-73!GO:0030529;ribonucleoprotein complex;1.06516261659597e-68!GO:0005515;protein binding;6.93710936737616e-68!GO:0010467;gene expression;1.46736559897444e-66!GO:0043233;organelle lumen;9.6235262526469e-62!GO:0031974;membrane-enclosed lumen;9.6235262526469e-62!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.19247295279218e-59!GO:0031981;nuclear lumen;2.37476514686522e-50!GO:0019538;protein metabolic process;7.61896533472367e-50!GO:0003676;nucleic acid binding;8.6680221923742e-49!GO:0044267;cellular protein metabolic process;2.73108935789675e-48!GO:0044260;cellular macromolecule metabolic process;2.39166561219654e-47!GO:0033036;macromolecule localization;2.0866657196134e-46!GO:0006396;RNA processing;2.93520615103287e-46!GO:0015031;protein transport;3.10512025701987e-44!GO:0006412;translation;2.60278557089143e-43!GO:0016071;mRNA metabolic process;5.87884358409947e-43!GO:0045184;establishment of protein localization;1.26794863996551e-42!GO:0008104;protein localization;2.69160814168455e-42!GO:0043234;protein complex;1.03920825287071e-40!GO:0016070;RNA metabolic process;1.82613696382218e-40!GO:0008380;RNA splicing;4.06000504264468e-37!GO:0006397;mRNA processing;7.57455828256685e-36!GO:0005840;ribosome;5.28907246151502e-35!GO:0031090;organelle membrane;7.53567867392429e-34!GO:0005739;mitochondrion;9.42266763481659e-34!GO:0009059;macromolecule biosynthetic process;1.38287506350282e-33!GO:0005654;nucleoplasm;1.94412541418508e-33!GO:0046907;intracellular transport;1.7401056565458e-32!GO:0016043;cellular component organization and biogenesis;4.17750718612724e-32!GO:0006259;DNA metabolic process;6.94635463290316e-31!GO:0003735;structural constituent of ribosome;7.93887694620864e-31!GO:0006886;intracellular protein transport;2.74100594478133e-30!GO:0031967;organelle envelope;2.89365814454607e-30!GO:0031975;envelope;5.9552358625603e-30!GO:0000166;nucleotide binding;6.83759253641988e-29!GO:0033279;ribosomal subunit;8.88214923516648e-29!GO:0005829;cytosol;1.60940690018163e-28!GO:0006512;ubiquitin cycle;8.06985693795998e-28!GO:0044451;nucleoplasm part;9.38743750944738e-28!GO:0005681;spliceosome;1.07640648720809e-27!GO:0065003;macromolecular complex assembly;1.3819139692664e-27!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.40127055550709e-26!GO:0043412;biopolymer modification;4.33255834292343e-26!GO:0012501;programmed cell death;5.2705992530735e-25!GO:0044429;mitochondrial part;6.69109075999469e-25!GO:0006915;apoptosis;8.25284106847539e-25!GO:0022607;cellular component assembly;1.28439252391782e-24!GO:0006996;organelle organization and biogenesis;3.21427302614873e-24!GO:0008219;cell death;4.25573860677188e-24!GO:0016265;death;4.25573860677188e-24!GO:0009058;biosynthetic process;7.20699252772953e-24!GO:0050794;regulation of cellular process;8.40659297028591e-24!GO:0051641;cellular localization;9.9285271956778e-24!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.25208915145662e-23!GO:0051649;establishment of cellular localization;1.35070799646513e-23!GO:0006464;protein modification process;2.02917630459433e-23!GO:0008134;transcription factor binding;8.14116574921737e-23!GO:0044249;cellular biosynthetic process;1.17007044524457e-22!GO:0043687;post-translational protein modification;1.74455961540303e-22!GO:0044445;cytosolic part;6.50636451902055e-22!GO:0032553;ribonucleotide binding;3.68381107355477e-21!GO:0032555;purine ribonucleotide binding;3.68381107355477e-21!GO:0017076;purine nucleotide binding;7.51764225018649e-20!GO:0017111;nucleoside-triphosphatase activity;1.75789894176388e-19!GO:0019222;regulation of metabolic process;1.90411539955579e-19!GO:0016462;pyrophosphatase activity;2.20075877216268e-19!GO:0019941;modification-dependent protein catabolic process;2.20075877216268e-19!GO:0043632;modification-dependent macromolecule catabolic process;2.20075877216268e-19!GO:0051603;proteolysis involved in cellular protein catabolic process;2.29798173847082e-19!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.33126284233196e-19!GO:0006511;ubiquitin-dependent protein catabolic process;2.36279658015076e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;2.97129796068941e-19!GO:0044257;cellular protein catabolic process;7.45776389025259e-19!GO:0016874;ligase activity;9.73832885580035e-19!GO:0016604;nuclear body;5.50032398578475e-18!GO:0044265;cellular macromolecule catabolic process;5.50032398578475e-18!GO:0006605;protein targeting;9.7490849537195e-18!GO:0050789;regulation of biological process;1.25847409856664e-17!GO:0006913;nucleocytoplasmic transport;1.51697529525202e-17!GO:0051169;nuclear transport;3.16291878276666e-17!GO:0005524;ATP binding;3.16291878276666e-17!GO:0043228;non-membrane-bound organelle;3.923369381372e-17!GO:0043232;intracellular non-membrane-bound organelle;3.923369381372e-17!GO:0006325;establishment and/or maintenance of chromatin architecture;6.48224044808641e-17!GO:0005740;mitochondrial envelope;6.99153362997116e-17!GO:0022618;protein-RNA complex assembly;7.41027504690963e-17!GO:0005730;nucleolus;7.95832509414099e-17!GO:0032559;adenyl ribonucleotide binding;1.02113190600295e-16!GO:0042981;regulation of apoptosis;1.09913289531044e-16!GO:0031323;regulation of cellular metabolic process;1.63835785512447e-16!GO:0043067;regulation of programmed cell death;1.65489403311529e-16!GO:0007049;cell cycle;1.76917852958243e-16!GO:0031966;mitochondrial membrane;1.86324021749106e-16!GO:0006323;DNA packaging;4.03778819964462e-16!GO:0051276;chromosome organization and biogenesis;7.17844010256109e-16!GO:0043285;biopolymer catabolic process;9.48931056891618e-16!GO:0019866;organelle inner membrane;1.08790552818851e-15!GO:0006350;transcription;1.8262571285547e-15!GO:0030554;adenyl nucleotide binding;2.451527908993e-15!GO:0008135;translation factor activity, nucleic acid binding;4.06958725497822e-15!GO:0015934;large ribosomal subunit;4.91431154711229e-15!GO:0016607;nuclear speck;5.31517718607502e-15!GO:0006974;response to DNA damage stimulus;6.22869257942642e-15!GO:0005635;nuclear envelope;7.08742989886613e-15!GO:0015935;small ribosomal subunit;9.63131996291823e-15!GO:0031965;nuclear membrane;1.52028720641902e-14!GO:0012505;endomembrane system;1.97135917400218e-14!GO:0006119;oxidative phosphorylation;2.20589193487035e-14!GO:0003712;transcription cofactor activity;2.45068266640028e-14!GO:0010468;regulation of gene expression;3.14395477532004e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);9.02785952119706e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.77181234885259e-13!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.97771977687936e-13!GO:0005743;mitochondrial inner membrane;2.31268370403262e-13!GO:0042623;ATPase activity, coupled;2.60071746957118e-13!GO:0030163;protein catabolic process;2.98994428637835e-13!GO:0006366;transcription from RNA polymerase II promoter;3.5843141390588e-13!GO:0016887;ATPase activity;4.70893093053561e-13!GO:0006793;phosphorus metabolic process;5.05398430821683e-13!GO:0006796;phosphate metabolic process;5.05398430821683e-13!GO:0009057;macromolecule catabolic process;5.77536159562368e-13!GO:0000398;nuclear mRNA splicing, via spliceosome;6.68047771309848e-13!GO:0000375;RNA splicing, via transesterification reactions;6.68047771309848e-13!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;6.68047771309848e-13!GO:0004386;helicase activity;9.25201954367759e-13!GO:0044453;nuclear membrane part;1.05943550742014e-12!GO:0016568;chromatin modification;1.64647752309707e-12!GO:0032774;RNA biosynthetic process;1.95017133804125e-12!GO:0006351;transcription, DNA-dependent;1.97345525564568e-12!GO:0017038;protein import;2.73239194004369e-12!GO:0006281;DNA repair;4.17858143867509e-12!GO:0065007;biological regulation;6.38390653679629e-12!GO:0045449;regulation of transcription;7.15589884038835e-12!GO:0051726;regulation of cell cycle;1.18087396052833e-11!GO:0006457;protein folding;1.2120479492243e-11!GO:0000502;proteasome complex (sensu Eukaryota);1.2120479492243e-11!GO:0008639;small protein conjugating enzyme activity;1.2601448491338e-11!GO:0004842;ubiquitin-protein ligase activity;1.55517246368636e-11!GO:0044455;mitochondrial membrane part;1.65055721182293e-11!GO:0048770;pigment granule;1.6595649117158e-11!GO:0042470;melanosome;1.6595649117158e-11!GO:0048523;negative regulation of cellular process;1.77484435669486e-11!GO:0005794;Golgi apparatus;2.38646617122354e-11!GO:0000074;regulation of progression through cell cycle;2.65015543234003e-11!GO:0022402;cell cycle process;2.81193064578698e-11!GO:0019787;small conjugating protein ligase activity;3.36096412590315e-11!GO:0065004;protein-DNA complex assembly;3.6668863830481e-11!GO:0003743;translation initiation factor activity;4.04982417612118e-11!GO:0007243;protein kinase cascade;4.26401276874098e-11!GO:0008026;ATP-dependent helicase activity;5.3659507013476e-11!GO:0050657;nucleic acid transport;6.77465892984905e-11!GO:0051236;establishment of RNA localization;6.77465892984905e-11!GO:0050658;RNA transport;6.77465892984905e-11!GO:0006333;chromatin assembly or disassembly;8.14978082318208e-11!GO:0005694;chromosome;8.14978082318208e-11!GO:0008270;zinc ion binding;8.19247869760343e-11!GO:0016310;phosphorylation;8.28567075333185e-11!GO:0006403;RNA localization;8.28859300421087e-11!GO:0005643;nuclear pore;8.63076082349687e-11!GO:0006413;translational initiation;1.33451156225585e-10!GO:0044248;cellular catabolic process;2.23187288126517e-10!GO:0006355;regulation of transcription, DNA-dependent;2.45376434520208e-10!GO:0048193;Golgi vesicle transport;2.61766679800276e-10!GO:0031980;mitochondrial lumen;3.25953911498119e-10!GO:0005759;mitochondrial matrix;3.25953911498119e-10!GO:0005746;mitochondrial respiratory chain;3.39521500060458e-10!GO:0051170;nuclear import;3.39521500060458e-10!GO:0006606;protein import into nucleus;3.39521500060458e-10!GO:0006446;regulation of translational initiation;3.71614416457912e-10!GO:0048519;negative regulation of biological process;4.50863905319273e-10!GO:0005768;endosome;1.21323218566942e-09!GO:0007242;intracellular signaling cascade;1.78734481981069e-09!GO:0051246;regulation of protein metabolic process;1.91421341582971e-09!GO:0065009;regulation of a molecular function;2.3334263269627e-09!GO:0031324;negative regulation of cellular metabolic process;2.42510490613435e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.61717225459527e-09!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.75676722099761e-09!GO:0044427;chromosomal part;2.75676722099761e-09!GO:0009719;response to endogenous stimulus;3.71048529442959e-09!GO:0016881;acid-amino acid ligase activity;3.78322146686476e-09!GO:0003677;DNA binding;3.80111606735127e-09!GO:0051082;unfolded protein binding;3.99361390661528e-09!GO:0050136;NADH dehydrogenase (quinone) activity;4.29117301921073e-09!GO:0003954;NADH dehydrogenase activity;4.29117301921073e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;4.29117301921073e-09!GO:0051028;mRNA transport;4.42158123276102e-09!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.63715966284392e-09!GO:0016564;transcription repressor activity;4.78830679538859e-09!GO:0016192;vesicle-mediated transport;5.25823849338e-09!GO:0016563;transcription activator activity;6.26422536954464e-09!GO:0046930;pore complex;9.10326557169021e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.35997467404775e-09!GO:0003713;transcription coactivator activity;1.2293870216931e-08!GO:0043065;positive regulation of apoptosis;1.64146824238429e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.81175649777393e-08!GO:0006917;induction of apoptosis;2.05847116927387e-08!GO:0045786;negative regulation of progression through cell cycle;2.25019218265346e-08!GO:0043566;structure-specific DNA binding;2.36608197912088e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;2.42125999153817e-08!GO:0043068;positive regulation of programmed cell death;2.568148810601e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.65171534140115e-08!GO:0000785;chromatin;2.94902416659343e-08!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.06666063461319e-08!GO:0012502;induction of programmed cell death;3.58465885546196e-08!GO:0042254;ribosome biogenesis and assembly;3.8336441070394e-08!GO:0065002;intracellular protein transport across a membrane;4.47982090883126e-08!GO:0042775;organelle ATP synthesis coupled electron transport;4.63537276595649e-08!GO:0042773;ATP synthesis coupled electron transport;4.63537276595649e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;4.9114455040575e-08!GO:0043069;negative regulation of programmed cell death;5.34044758420803e-08!GO:0009892;negative regulation of metabolic process;5.76199387810662e-08!GO:0019829;cation-transporting ATPase activity;7.00031404844819e-08!GO:0003697;single-stranded DNA binding;8.21564504214325e-08!GO:0043066;negative regulation of apoptosis;8.80097239915494e-08!GO:0016481;negative regulation of transcription;8.89843908514294e-08!GO:0032446;protein modification by small protein conjugation;9.18642020740188e-08!GO:0008565;protein transporter activity;1.00696335104661e-07!GO:0016740;transferase activity;1.06176032165198e-07!GO:0030964;NADH dehydrogenase complex (quinone);1.21099929275873e-07!GO:0045271;respiratory chain complex I;1.21099929275873e-07!GO:0005747;mitochondrial respiratory chain complex I;1.21099929275873e-07!GO:0046914;transition metal ion binding;1.49167055427659e-07!GO:0016567;protein ubiquitination;1.71987254829071e-07!GO:0019899;enzyme binding;1.97157017217455e-07!GO:0006916;anti-apoptosis;2.30116108167054e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.39635449892919e-07!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.87425449778514e-07!GO:0004674;protein serine/threonine kinase activity;3.00629817287668e-07!GO:0044432;endoplasmic reticulum part;4.17564735996353e-07!GO:0000151;ubiquitin ligase complex;6.84264694670142e-07!GO:0006260;DNA replication;6.84264694670142e-07!GO:0016787;hydrolase activity;7.55096752486695e-07!GO:0031497;chromatin assembly;8.58361597620649e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;9.29951189099103e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.05918841201338e-06!GO:0006334;nucleosome assembly;1.22651760666164e-06!GO:0005783;endoplasmic reticulum;1.5619514564599e-06!GO:0030532;small nuclear ribonucleoprotein complex;1.62806627132914e-06!GO:0051168;nuclear export;1.89413789863656e-06!GO:0003714;transcription corepressor activity;1.95419536122715e-06!GO:0000278;mitotic cell cycle;2.91607328051341e-06!GO:0051186;cofactor metabolic process;3.5584802445478e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.93070307195155e-06!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.9854798735842e-06!GO:0005525;GTP binding;4.69809640291648e-06!GO:0016072;rRNA metabolic process;5.1189441279879e-06!GO:0005789;endoplasmic reticulum membrane;5.91526960547854e-06!GO:0050790;regulation of catalytic activity;6.24336696631486e-06!GO:0005839;proteasome core complex (sensu Eukaryota);6.30945061235134e-06!GO:0006364;rRNA processing;6.30945061235134e-06!GO:0003924;GTPase activity;6.99527723904977e-06!GO:0005761;mitochondrial ribosome;7.2832305600037e-06!GO:0000313;organellar ribosome;7.2832305600037e-06!GO:0006888;ER to Golgi vesicle-mediated transport;7.32095991752668e-06!GO:0015986;ATP synthesis coupled proton transport;7.62656068005079e-06!GO:0015985;energy coupled proton transport, down electrochemical gradient;7.62656068005079e-06!GO:0006399;tRNA metabolic process;7.90064575019858e-06!GO:0000245;spliceosome assembly;8.14929513639535e-06!GO:0003724;RNA helicase activity;8.14929513639535e-06!GO:0048522;positive regulation of cellular process;8.88698366992507e-06!GO:0044440;endosomal part;8.92702818883485e-06!GO:0010008;endosome membrane;8.92702818883485e-06!GO:0009260;ribonucleotide biosynthetic process;9.36025639132989e-06!GO:0007264;small GTPase mediated signal transduction;9.41490366302121e-06!GO:0009259;ribonucleotide metabolic process;9.87886429481865e-06!GO:0005793;ER-Golgi intermediate compartment;1.03044919615063e-05!GO:0009060;aerobic respiration;1.03192501817096e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.05287123401977e-05!GO:0015078;hydrogen ion transmembrane transporter activity;1.0580753350231e-05!GO:0006461;protein complex assembly;1.15342061394683e-05!GO:0006402;mRNA catabolic process;1.24911070102696e-05!GO:0060090;molecular adaptor activity;1.33368107376552e-05!GO:0006417;regulation of translation;1.50359987833047e-05!GO:0042110;T cell activation;1.51985037709424e-05!GO:0009152;purine ribonucleotide biosynthetic process;1.54435020951209e-05!GO:0006401;RNA catabolic process;1.81597589730903e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.98271499229347e-05!GO:0015399;primary active transmembrane transporter activity;1.98271499229347e-05!GO:0004298;threonine endopeptidase activity;2.15566457455204e-05!GO:0006164;purine nucleotide biosynthetic process;2.24866427890129e-05!GO:0016469;proton-transporting two-sector ATPase complex;2.27493145857366e-05!GO:0008234;cysteine-type peptidase activity;2.63919861500217e-05!GO:0016363;nuclear matrix;2.9722856223591e-05!GO:0030120;vesicle coat;3.25659853230274e-05!GO:0030662;coated vesicle membrane;3.25659853230274e-05!GO:0046649;lymphocyte activation;3.30479811574457e-05!GO:0009142;nucleoside triphosphate biosynthetic process;3.39799796569857e-05!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.39799796569857e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.49936646716627e-05!GO:0009150;purine ribonucleotide metabolic process;3.75087411702607e-05!GO:0005770;late endosome;3.79567490008546e-05!GO:0048475;coated membrane;3.79567490008546e-05!GO:0030117;membrane coat;3.79567490008546e-05!GO:0006732;coenzyme metabolic process;3.80748664952108e-05!GO:0005813;centrosome;4.01070839756821e-05!GO:0006754;ATP biosynthetic process;4.15021668629875e-05!GO:0006753;nucleoside phosphate metabolic process;4.15021668629875e-05!GO:0008632;apoptotic program;4.16899157656487e-05!GO:0032561;guanyl ribonucleotide binding;4.25731234288509e-05!GO:0019001;guanyl nucleotide binding;4.25731234288509e-05!GO:0006163;purine nucleotide metabolic process;4.72273084635055e-05!GO:0031326;regulation of cellular biosynthetic process;5.32635920106027e-05!GO:0006352;transcription initiation;5.49492022741672e-05!GO:0044431;Golgi apparatus part;5.62178438446623e-05!GO:0045259;proton-transporting ATP synthase complex;5.62178438446623e-05!GO:0007265;Ras protein signal transduction;5.78379419446819e-05!GO:0045333;cellular respiration;6.43799482400173e-05!GO:0009056;catabolic process;6.56825727263711e-05!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;6.95565751176011e-05!GO:0009145;purine nucleoside triphosphate biosynthetic process;6.95565751176011e-05!GO:0009967;positive regulation of signal transduction;7.03221664880717e-05!GO:0016779;nucleotidyltransferase activity;7.14111656774372e-05!GO:0030695;GTPase regulator activity;7.23464450922502e-05!GO:0009966;regulation of signal transduction;7.52192062172346e-05!GO:0006613;cotranslational protein targeting to membrane;8.10934756366262e-05!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;8.87370278457764e-05!GO:0004812;aminoacyl-tRNA ligase activity;8.87370278457764e-05!GO:0016875;ligase activity, forming carbon-oxygen bonds;8.87370278457764e-05!GO:0001772;immunological synapse;8.93891942089479e-05!GO:0009615;response to virus;9.07619779396999e-05!GO:0016197;endosome transport;0.000100137479576632!GO:0008186;RNA-dependent ATPase activity;0.000111215435168324!GO:0009199;ribonucleoside triphosphate metabolic process;0.000113941348100623!GO:0005815;microtubule organizing center;0.000116159328672741!GO:0045892;negative regulation of transcription, DNA-dependent;0.000125854342255337!GO:0005773;vacuole;0.000128150928428322!GO:0005667;transcription factor complex;0.000129658865795178!GO:0003729;mRNA binding;0.000137656602465763!GO:0007005;mitochondrion organization and biogenesis;0.000141776719347968!GO:0043492;ATPase activity, coupled to movement of substances;0.00014629152250997!GO:0043623;cellular protein complex assembly;0.000146553015130601!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00014659691149521!GO:0016251;general RNA polymerase II transcription factor activity;0.000147860913015837!GO:0009889;regulation of biosynthetic process;0.000174967940397342!GO:0009141;nucleoside triphosphate metabolic process;0.000176231350528497!GO:0043038;amino acid activation;0.00017861212036299!GO:0006418;tRNA aminoacylation for protein translation;0.00017861212036299!GO:0043039;tRNA aminoacylation;0.00017861212036299!GO:0016301;kinase activity;0.000181393972581737!GO:0019783;small conjugating protein-specific protease activity;0.000185823003311148!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000190075733219557!GO:0046034;ATP metabolic process;0.000211141540908833!GO:0009205;purine ribonucleoside triphosphate metabolic process;0.000219952562629507!GO:0009144;purine nucleoside triphosphate metabolic process;0.000219952562629507!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000220671692108288!GO:0051188;cofactor biosynthetic process;0.000227130918044804!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000241981515493519!GO:0031252;leading edge;0.000242631446932985!GO:0008654;phospholipid biosynthetic process;0.000246035009175164!GO:0005769;early endosome;0.000246035009175164!GO:0015631;tubulin binding;0.000246584747780641!GO:0048518;positive regulation of biological process;0.000250683460313871!GO:0005083;small GTPase regulator activity;0.000260285437687748!GO:0045321;leukocyte activation;0.000273564889804236!GO:0048468;cell development;0.000280886868239372!GO:0008047;enzyme activator activity;0.000287035205182476!GO:0004843;ubiquitin-specific protease activity;0.000288476712778241!GO:0003690;double-stranded DNA binding;0.000303828004774543!GO:0005070;SH3/SH2 adaptor activity;0.000322429847787386!GO:0004004;ATP-dependent RNA helicase activity;0.00032422974618939!GO:0022415;viral reproductive process;0.000326188413922228!GO:0042101;T cell receptor complex;0.000333707562516799!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000339620806081075!GO:0015630;microtubule cytoskeleton;0.000387090434249536!GO:0006261;DNA-dependent DNA replication;0.000398893095393138!GO:0006607;NLS-bearing substrate import into nucleus;0.000435125228487181!GO:0006099;tricarboxylic acid cycle;0.000436678494909109!GO:0046356;acetyl-CoA catabolic process;0.000436678494909109!GO:0030384;phosphoinositide metabolic process;0.000476390222882515!GO:0048471;perinuclear region of cytoplasm;0.000491107594152154!GO:0009055;electron carrier activity;0.000516900631529238!GO:0051427;hormone receptor binding;0.000538950523380755!GO:0008287;protein serine/threonine phosphatase complex;0.000547546922427304!GO:0006310;DNA recombination;0.000567602200603818!GO:0005885;Arp2/3 protein complex;0.000580553214133679!GO:0000323;lytic vacuole;0.000604389229478493!GO:0005764;lysosome;0.000604389229478493!GO:0051251;positive regulation of lymphocyte activation;0.000623450897885287!GO:0005637;nuclear inner membrane;0.000655836743266573!GO:0022403;cell cycle phase;0.000655836743266573!GO:0007050;cell cycle arrest;0.000662891065637982!GO:0006612;protein targeting to membrane;0.000665953458647764!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000713992703235654!GO:0006611;protein export from nucleus;0.000780215315979605!GO:0004221;ubiquitin thiolesterase activity;0.000783206747033789!GO:0006084;acetyl-CoA metabolic process;0.000797912417781815!GO:0046983;protein dimerization activity;0.000838161964658966!GO:0035257;nuclear hormone receptor binding;0.000956040661723524!GO:0006468;protein amino acid phosphorylation;0.00102290165366574!GO:0000139;Golgi membrane;0.00106472392333198!GO:0009108;coenzyme biosynthetic process;0.0010765708756689!GO:0005096;GTPase activator activity;0.00114292091894007!GO:0051789;response to protein stimulus;0.00117078805559219!GO:0006986;response to unfolded protein;0.00117078805559219!GO:0006414;translational elongation;0.00117172635235108!GO:0006752;group transfer coenzyme metabolic process;0.0012335893861641!GO:0006891;intra-Golgi vesicle-mediated transport;0.00131617477169558!GO:0016311;dephosphorylation;0.00145680225912811!GO:0005798;Golgi-associated vesicle;0.00150551624215018!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00154205220022827!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00154661058992808!GO:0051329;interphase of mitotic cell cycle;0.00167236787182203!GO:0046489;phosphoinositide biosynthetic process;0.00169685947691448!GO:0051338;regulation of transferase activity;0.00170932634370888!GO:0051090;regulation of transcription factor activity;0.00171296754339657!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00184839083828976!GO:0043021;ribonucleoprotein binding;0.00190395124900453!GO:0043549;regulation of kinase activity;0.00190522973598268!GO:0006650;glycerophospholipid metabolic process;0.00201043133032287!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00204376539413339!GO:0033673;negative regulation of kinase activity;0.00213982471355456!GO:0006469;negative regulation of protein kinase activity;0.00213982471355456!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00216084166338256!GO:0005774;vacuolar membrane;0.0021981125840897!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00230929279627999!GO:0009109;coenzyme catabolic process;0.00235963166846581!GO:0045941;positive regulation of transcription;0.00245407827220522!GO:0007034;vacuolar transport;0.00250664525283312!GO:0051301;cell division;0.00252310297393215!GO:0006405;RNA export from nucleus;0.00252754255798505!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00263180121298291!GO:0031902;late endosome membrane;0.00269731846716034!GO:0051252;regulation of RNA metabolic process;0.00273368050543232!GO:0031625;ubiquitin protein ligase binding;0.00274124043961094!GO:0051325;interphase;0.00285984126777889!GO:0042802;identical protein binding;0.00288181423568308!GO:0008017;microtubule binding;0.00288313354303745!GO:0003746;translation elongation factor activity;0.00296984440157459!GO:0030658;transport vesicle membrane;0.00298550414487283!GO:0008022;protein C-terminus binding;0.0029925172897384!GO:0051348;negative regulation of transferase activity;0.00301765409691545!GO:0019843;rRNA binding;0.00307811234191119!GO:0008139;nuclear localization sequence binding;0.00310901088409659!GO:0000087;M phase of mitotic cell cycle;0.00322473449051046!GO:0005741;mitochondrial outer membrane;0.00335731801043213!GO:0019867;outer membrane;0.00349093416416281!GO:0045859;regulation of protein kinase activity;0.0035148946375959!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.0037147366455357!GO:0006338;chromatin remodeling;0.00373689694170665!GO:0003678;DNA helicase activity;0.00403265681883523!GO:0043488;regulation of mRNA stability;0.00403265681883523!GO:0043487;regulation of RNA stability;0.00403265681883523!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00403265681883523!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00403265681883523!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00403265681883523!GO:0031968;organelle outer membrane;0.00409222496162121!GO:0007067;mitosis;0.00414005172182487!GO:0005765;lysosomal membrane;0.00417427112029305!GO:0031072;heat shock protein binding;0.00425758426688865!GO:0016584;nucleosome positioning;0.0042918216591438!GO:0046474;glycerophospholipid biosynthetic process;0.00433955546061327!GO:0016585;chromatin remodeling complex;0.00443203687199479!GO:0031982;vesicle;0.00447051709726347!GO:0045603;positive regulation of endothelial cell differentiation;0.00447051709726347!GO:0046822;regulation of nucleocytoplasmic transport;0.00466143161744996!GO:0051187;cofactor catabolic process;0.0049672154656996!GO:0001819;positive regulation of cytokine production;0.00496808198745631!GO:0019901;protein kinase binding;0.00497604029721415!GO:0051336;regulation of hydrolase activity;0.0050154796056532!GO:0005048;signal sequence binding;0.00511050503667648!GO:0016791;phosphoric monoester hydrolase activity;0.00518717024243206!GO:0046966;thyroid hormone receptor binding;0.00525894891678565!GO:0003899;DNA-directed RNA polymerase activity;0.0053277662386823!GO:0044437;vacuolar part;0.0053459547287459!GO:0051223;regulation of protein transport;0.00541954227751915!GO:0051052;regulation of DNA metabolic process;0.00546548389769268!GO:0005669;transcription factor TFIID complex;0.00548998712678234!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00577389348688328!GO:0051092;activation of NF-kappaB transcription factor;0.00596323673575746!GO:0000786;nucleosome;0.00599533058073728!GO:0045893;positive regulation of transcription, DNA-dependent;0.00613896943217565!GO:0030258;lipid modification;0.00615193030232078!GO:0004722;protein serine/threonine phosphatase activity;0.00627803919126352!GO:0003682;chromatin binding;0.00649146816459517!GO:0005684;U2-dependent spliceosome;0.0064933211653335!GO:0006383;transcription from RNA polymerase III promoter;0.00649364369471712!GO:0016790;thiolester hydrolase activity;0.00673832634518128!GO:0030518;steroid hormone receptor signaling pathway;0.00678425303497882!GO:0009893;positive regulation of metabolic process;0.006812831296392!GO:0048500;signal recognition particle;0.00683148747710773!GO:0003725;double-stranded RNA binding;0.00690118368510798!GO:0019904;protein domain specific binding;0.00691447553121564!GO:0017091;AU-rich element binding;0.00695188243274797!GO:0050779;RNA destabilization;0.00695188243274797!GO:0000289;poly(A) tail shortening;0.00695188243274797!GO:0030660;Golgi-associated vesicle membrane;0.00771003809606616!GO:0006984;ER-nuclear signaling pathway;0.00771954294007705!GO:0004721;phosphoprotein phosphatase activity;0.00778111664661518!GO:0003684;damaged DNA binding;0.007986309326103!GO:0005057;receptor signaling protein activity;0.00799921722735594!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0084567835729305!GO:0005657;replication fork;0.00851877255077319!GO:0006470;protein amino acid dephosphorylation;0.00858466940612928!GO:0032940;secretion by cell;0.00875498374907789!GO:0003711;transcription elongation regulator activity;0.00876386070558313!GO:0043414;biopolymer methylation;0.00889042344958699!GO:0043087;regulation of GTPase activity;0.00927628048155505!GO:0030217;T cell differentiation;0.00963749384275032!GO:0051098;regulation of binding;0.00975756561032548!GO:0000082;G1/S transition of mitotic cell cycle;0.00982577165619455!GO:0003702;RNA polymerase II transcription factor activity;0.00998965106471241!GO:0008637;apoptotic mitochondrial changes;0.0101473088096958!GO:0001726;ruffle;0.0103006042317162!GO:0051059;NF-kappaB binding;0.0105917905066986!GO:0006818;hydrogen transport;0.0106075998739526!GO:0006376;mRNA splice site selection;0.0108807848384427!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0108807848384427!GO:0032200;telomere organization and biogenesis;0.0109770064455223!GO:0000723;telomere maintenance;0.0109770064455223!GO:0033116;ER-Golgi intermediate compartment membrane;0.011103361603347!GO:0000287;magnesium ion binding;0.011103361603347!GO:0018193;peptidyl-amino acid modification;0.0111851345276133!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0111888209997032!GO:0000059;protein import into nucleus, docking;0.0114740382260663!GO:0031410;cytoplasmic vesicle;0.0114809873169564!GO:0051235;maintenance of localization;0.0114809873169564!GO:0001775;cell activation;0.0118582845415935!GO:0000118;histone deacetylase complex;0.0118821854432918!GO:0015923;mannosidase activity;0.0118821854432918!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.0119039159357526!GO:0019058;viral infectious cycle;0.0119044665855156!GO:0008168;methyltransferase activity;0.0119328154694697!GO:0042287;MHC protein binding;0.0120988412904805!GO:0000049;tRNA binding;0.0121248458782679!GO:0048487;beta-tubulin binding;0.0122139588752729!GO:0046467;membrane lipid biosynthetic process;0.0122139588752729!GO:0051539;4 iron, 4 sulfur cluster binding;0.0122869796807959!GO:0044452;nucleolar part;0.0124975605697565!GO:0016741;transferase activity, transferring one-carbon groups;0.0126021866986231!GO:0015992;proton transport;0.0126370985645451!GO:0043407;negative regulation of MAP kinase activity;0.0126774975694141!GO:0008312;7S RNA binding;0.0127800457239215!GO:0030968;unfolded protein response;0.0128218509289447!GO:0005819;spindle;0.0129900970079405!GO:0032508;DNA duplex unwinding;0.0129900970079405!GO:0032392;DNA geometric change;0.0129900970079405!GO:0030521;androgen receptor signaling pathway;0.013006035849534!GO:0051249;regulation of lymphocyte activation;0.0130112270804318!GO:0006302;double-strand break repair;0.0130651340250085!GO:0031988;membrane-bound vesicle;0.0132485238074023!GO:0016605;PML body;0.0132669228975859!GO:0040029;regulation of gene expression, epigenetic;0.0133465574835013!GO:0050865;regulation of cell activation;0.01335241914295!GO:0004672;protein kinase activity;0.01335241914295!GO:0030145;manganese ion binding;0.0134401701109227!GO:0005762;mitochondrial large ribosomal subunit;0.0134555293832882!GO:0000315;organellar large ribosomal subunit;0.0134555293832882!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0135684246537537!GO:0045047;protein targeting to ER;0.0135684246537537!GO:0006919;caspase activation;0.0136558093080729!GO:0000209;protein polyubiquitination;0.0136689663839141!GO:0030127;COPII vesicle coat;0.0136689663839141!GO:0012507;ER to Golgi transport vesicle membrane;0.0136689663839141!GO:0004527;exonuclease activity;0.0137003717409113!GO:0050870;positive regulation of T cell activation;0.0137003717409113!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0138173920815492!GO:0002757;immune response-activating signal transduction;0.0139217778481832!GO:0002376;immune system process;0.0140005139745255!GO:0022890;inorganic cation transmembrane transporter activity;0.0140005139745255!GO:0007041;lysosomal transport;0.0140210788493562!GO:0000060;protein import into nucleus, translocation;0.0141625542641475!GO:0008276;protein methyltransferase activity;0.0141625542641475!GO:0019210;kinase inhibitor activity;0.0143533314051798!GO:0045045;secretory pathway;0.0147507047770994!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0148426368828886!GO:0008601;protein phosphatase type 2A regulator activity;0.0150589764738209!GO:0030118;clathrin coat;0.015313870828683!GO:0019079;viral genome replication;0.0157987643952851!GO:0050871;positive regulation of B cell activation;0.0157987643952851!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0159301013679613!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0160365427305829!GO:0043621;protein self-association;0.0160627671488108!GO:0006354;RNA elongation;0.0160975748890566!GO:0033549;MAP kinase phosphatase activity;0.016107777143897!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.016107777143897!GO:0046854;phosphoinositide phosphorylation;0.0161543575521617!GO:0000781;chromosome, telomeric region;0.0164801001753204!GO:0005521;lamin binding;0.0166164374433358!GO:0004177;aminopeptidase activity;0.0169353560256408!GO:0030867;rough endoplasmic reticulum membrane;0.0175066697355231!GO:0016788;hydrolase activity, acting on ester bonds;0.0175080697655869!GO:0043681;protein import into mitochondrion;0.0177272267553448!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0178000691521882!GO:0008624;induction of apoptosis by extracellular signals;0.0181522332481113!GO:0032259;methylation;0.0181709362367643!GO:0004860;protein kinase inhibitor activity;0.0183519959663872!GO:0000188;inactivation of MAPK activity;0.018858861853108!GO:0005791;rough endoplasmic reticulum;0.0190273121015966!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0192456753505976!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0192895328156834!GO:0043433;negative regulation of transcription factor activity;0.0195600766110912!GO:0043022;ribosome binding;0.0195600766110912!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0199358284319928!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0199760600842307!GO:0050811;GABA receptor binding;0.0199760600842307!GO:0030522;intracellular receptor-mediated signaling pathway;0.0201841568924091!GO:0000119;mediator complex;0.0202482804149049!GO:0030134;ER to Golgi transport vesicle;0.0203970965904965!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0203970965904965!GO:0004715;non-membrane spanning protein tyrosine kinase activity;0.0205200407668927!GO:0019900;kinase binding;0.0207136288305642!GO:0005869;dynactin complex;0.0211399955235761!GO:0045746;negative regulation of Notch signaling pathway;0.0216901323470211!GO:0001909;leukocyte mediated cytotoxicity;0.0218154891932053!GO:0046578;regulation of Ras protein signal transduction;0.0220337288380026!GO:0022411;cellular component disassembly;0.022034134910316!GO:0046834;lipid phosphorylation;0.0223037356572026!GO:0031901;early endosome membrane;0.0225554707128298!GO:0046426;negative regulation of JAK-STAT cascade;0.0227480927657058!GO:0045185;maintenance of protein localization;0.0227480927657058!GO:0003950;NAD+ ADP-ribosyltransferase activity;0.0228191064896663!GO:0006289;nucleotide-excision repair;0.0230220051420001!GO:0006672;ceramide metabolic process;0.0237413974932702!GO:0016569;covalent chromatin modification;0.0237413974932702!GO:0006661;phosphatidylinositol biosynthetic process;0.0239163636609475!GO:0031647;regulation of protein stability;0.0242117314461547!GO:0030880;RNA polymerase complex;0.0242117314461547!GO:0008033;tRNA processing;0.0243535337147478!GO:0016023;cytoplasmic membrane-bound vesicle;0.0247038289707975!GO:0005099;Ras GTPase activator activity;0.0249586627724141!GO:0002764;immune response-regulating signal transduction;0.025218653964595!GO:0016859;cis-trans isomerase activity;0.0253067084552022!GO:0000159;protein phosphatase type 2A complex;0.0266556983769883!GO:0007006;mitochondrial membrane organization and biogenesis;0.026660655119798!GO:0006497;protein amino acid lipidation;0.0267576361761434!GO:0016570;histone modification;0.0274219097041583!GO:0007004;telomere maintenance via telomerase;0.0276531206274277!GO:0046519;sphingoid metabolic process;0.0276650680061795!GO:0032318;regulation of Ras GTPase activity;0.0276722325609294!GO:0045058;T cell selection;0.0278015115374145!GO:0051091;positive regulation of transcription factor activity;0.0284629430275067!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0288714359929466!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0288714359929466!GO:0031461;cullin-RING ubiquitin ligase complex;0.0294636143836642!GO:0046979;TAP2 binding;0.0294636143836642!GO:0046977;TAP binding;0.0294636143836642!GO:0046978;TAP1 binding;0.0294636143836642!GO:0004197;cysteine-type endopeptidase activity;0.0296450757323766!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.030209530792261!GO:0030433;ER-associated protein catabolic process;0.030610422315741!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.030610422315741!GO:0051087;chaperone binding;0.0311911359112352!GO:0004402;histone acetyltransferase activity;0.0312237263471732!GO:0004468;lysine N-acetyltransferase activity;0.0312237263471732!GO:0031325;positive regulation of cellular metabolic process;0.0312237263471732!GO:0006950;response to stress;0.0316691210601792!GO:0050852;T cell receptor signaling pathway;0.0317815284768716!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0318927997911937!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0318927997911937!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0318927997911937!GO:0050863;regulation of T cell activation;0.0321642136445489!GO:0048002;antigen processing and presentation of peptide antigen;0.0323206397487604!GO:0000279;M phase;0.0331351983285207!GO:0043284;biopolymer biosynthetic process;0.0332551161517807!GO:0001906;cell killing;0.0332616231677837!GO:0035026;leading edge cell differentiation;0.0335307903411515!GO:0047485;protein N-terminus binding;0.0345973085513829!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.03480915646903!GO:0043281;regulation of caspase activity;0.0354186050902164!GO:0042608;T cell receptor binding;0.0355692132891675!GO:0000314;organellar small ribosomal subunit;0.0358685687169954!GO:0005763;mitochondrial small ribosomal subunit;0.0358685687169954!GO:0035035;histone acetyltransferase binding;0.0362595758070899!GO:0032507;maintenance of cellular protein localization;0.0365783970305413!GO:0015980;energy derivation by oxidation of organic compounds;0.0366066050622579!GO:0002440;production of molecular mediator of immune response;0.0373363661899068!GO:0030036;actin cytoskeleton organization and biogenesis;0.0377063623299296!GO:0030674;protein binding, bridging;0.0378337422313009!GO:0008536;Ran GTPase binding;0.0381171261845329!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0381739847430838!GO:0000428;DNA-directed RNA polymerase complex;0.0381739847430838!GO:0016279;protein-lysine N-methyltransferase activity;0.0387304524038156!GO:0018024;histone-lysine N-methyltransferase activity;0.0387304524038156!GO:0016278;lysine N-methyltransferase activity;0.0387304524038156!GO:0043280;positive regulation of caspase activity;0.0387523296274655!GO:0045069;regulation of viral genome replication;0.0388684653776892!GO:0006506;GPI anchor biosynthetic process;0.0390128919451263!GO:0030176;integral to endoplasmic reticulum membrane;0.0393615655239487!GO:0001667;ameboidal cell migration;0.0393833023094456!GO:0032027;myosin light chain binding;0.0393833023094456!GO:0051457;maintenance of protein localization in nucleus;0.0394038628313038!GO:0004003;ATP-dependent DNA helicase activity;0.0394255605899036!GO:0045736;negative regulation of cyclin-dependent protein kinase activity;0.0400077739841495!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0400187736308152!GO:0031098;stress-activated protein kinase signaling pathway;0.0400887258108748!GO:0030097;hemopoiesis;0.0403185551605945!GO:0006595;polyamine metabolic process;0.0407901769025637!GO:0030833;regulation of actin filament polymerization;0.0412316392122718!GO:0000303;response to superoxide;0.0417094446853655!GO:0030137;COPI-coated vesicle;0.0421010894137117!GO:0016455;RNA polymerase II transcription mediator activity;0.0422337405897932!GO:0046982;protein heterodimerization activity;0.0426613285031948!GO:0033157;regulation of intracellular protein transport;0.0431734653148409!GO:0042306;regulation of protein import into nucleus;0.0431734653148409!GO:0000776;kinetochore;0.0432987623987272!GO:0006914;autophagy;0.0433644214396459!GO:0006268;DNA unwinding during replication;0.0435579774052434!GO:0051540;metal cluster binding;0.0436956189394093!GO:0051536;iron-sulfur cluster binding;0.0436956189394093!GO:0006626;protein targeting to mitochondrion;0.0437524417542484!GO:0016853;isomerase activity;0.0441759836754016!GO:0002520;immune system development;0.044226078846343!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0442366757414146!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0446020846197733!GO:0015002;heme-copper terminal oxidase activity;0.0446020846197733!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0446020846197733!GO:0004129;cytochrome-c oxidase activity;0.0446020846197733!GO:0006406;mRNA export from nucleus;0.0451448929025075!GO:0008629;induction of apoptosis by intracellular signals;0.0456927229138478!GO:0009117;nucleotide metabolic process;0.0456984498678106!GO:0008138;protein tyrosine/serine/threonine phosphatase activity;0.0459972365346298!GO:0007259;JAK-STAT cascade;0.0465118460579059!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0465782370764124!GO:0045926;negative regulation of growth;0.0465782370764124!GO:0006505;GPI anchor metabolic process;0.0465782370764124!GO:0008097;5S rRNA binding;0.0465782370764124!GO:0016581;NuRD complex;0.0467506976967408!GO:0051056;regulation of small GTPase mediated signal transduction;0.0473957622192517!GO:0035303;regulation of dephosphorylation;0.0476236076411212!GO:0050851;antigen receptor-mediated signaling pathway;0.0476291791768322!GO:0042054;histone methyltransferase activity;0.047818837536684!GO:0008094;DNA-dependent ATPase activity;0.0484311212932532!GO:0005095;GTPase inhibitor activity;0.0490661409091531!GO:0007030;Golgi organization and biogenesis;0.0490853097790066!GO:0045815;positive regulation of gene expression, epigenetic;0.0492504669019235!GO:0045061;thymic T cell selection;0.0493655620297363!GO:0030663;COPI coated vesicle membrane;0.0494490912453998!GO:0030126;COPI vesicle coat;0.0494490912453998
|sample_id=11311
|sample_id=11311
|sample_note=
|sample_note=
Line 76: Line 105:
|sample_tissue=blood
|sample_tissue=blood
|top_motifs=RORA:4.15651858328;T:3.70352324958;ATF4:3.66970768154;RFX2..5_RFXANK_RFXAP:3.5481318577;RUNX1..3:3.47038298513;CREB1:3.45525311346;PAX3,7:3.38917284335;ATF5_CREB3:3.33092805291;BPTF:2.98501587596;PITX1..3:2.97364388905;FOX{D1,D2}:2.96592390538;FOXP1:2.91730708309;NFKB1_REL_RELA:2.87506601897;FOXN1:2.51124031305;FOXO1,3,4:2.39132005603;ELF1,2,4:2.3837213114;DMAP1_NCOR{1,2}_SMARC:2.35166157424;ZBTB16:2.33473478236;PAX2:2.2811130744;RFX1:2.24102100516;ETS1,2:2.19189517297;FOX{F1,F2,J1}:2.11397797553;NKX2-1,4:2.0723335581;HMX1:2.05164485722;TBX4,5:2.01643870732;JUN:2.00118169184;TOPORS:1.85916048076;SPI1:1.7585223761;NKX6-1,2:1.73574882005;IKZF2:1.63529606383;TGIF1:1.62188185941;TLX2:1.54026349419;ATF6:1.39349830042;ZNF384:1.28054819895;IRF1,2:1.23189523634;ATF2:1.18648520394;SPIB:1.13334420694;FOX{I1,J2}:1.09760769471;BREu{core}:1.07875190175;HIF1A:1.03888330836;NANOG{mouse}:0.914716526608;LEF1_TCF7_TCF7L1,2:0.885068498108;PPARG:0.86834396739;FOSL2:0.755849156242;SMAD1..7,9:0.70596571432;EGR1..3:0.663321010975;FOS_FOS{B,L1}_JUN{B,D}:0.650264013258;MAFB:0.630982289417;EP300:0.600633504986;AIRE:0.600628617159;MYB:0.594001212882;PAX4:0.572483223935;CDX1,2,4:0.551317492613;HBP1_HMGB_SSRP1_UBTF:0.456044322495;ELK1,4_GABP{A,B1}:0.446250319862;PAX6:0.442571135295;TFDP1:0.381572022578;SREBF1,2:0.367909059392;RXRA_VDR{dimer}:0.34521345814;NFATC1..3:0.335530357783;BACH2:0.328600496937;FOXD3:0.30916545634;RREB1:0.282657881586;SOX2:0.26747947606;NKX3-1:0.25814082924;FOXP3:0.249457002819;FOXL1:0.228536830743;HMGA1,2:0.221083384826;GCM1,2:0.214347283464;STAT2,4,6:0.195854507317;NFIL3:0.18410192986;GATA6:0.183480128925;NFE2:0.143499432271;MYFfamily:0.127509906273;NFE2L1:0.0924848319046;HOX{A6,A7,B6,B7}:0.0889115752303;IRF7:-0.0193834572831;SOX5:-0.0224842294042;AHR_ARNT_ARNT2:-0.0823799675095;NFY{A,B,C}:-0.102939309832;PDX1:-0.159155796531;POU2F1..3:-0.193326923719;HES1:-0.224520198739;EVI1:-0.225561772231;DBP:-0.252688268492;FOXQ1:-0.255776013989;FOXM1:-0.26521706905;NFIX:-0.26747824847;TFAP4:-0.279689208073;NFE2L2:-0.294309985026;E2F1..5:-0.317798271484;SNAI1..3:-0.330861203689;CEBPA,B_DDIT3:-0.335625636665;MTE{core}:-0.349627975912;PBX1:-0.351431953024;NR5A1,2:-0.359556734301;CUX2:-0.37067892758;ZEB1:-0.385609125073;SRF:-0.39701031046;GLI1..3:-0.400019637883;HOXA9_MEIS1:-0.413736319655;MTF1:-0.418926536665;MED-1{core}:-0.436829979538;ZFP161:-0.555242138741;HNF4A_NR2F1,2:-0.56638865527;NRF1:-0.569790702558;STAT5{A,B}:-0.569982868138;SPZ1:-0.572614340063;MYOD1:-0.58448722168;TFAP2B:-0.585253987136;PATZ1:-0.615161902532;HLF:-0.628433433405;REST:-0.683242106167;PRRX1,2:-0.695058821721;NANOG:-0.730366257112;PAX5:-0.7512870846;TFAP2{A,C}:-0.752808176195;RBPJ:-0.777554109645;ALX4:-0.786980258749;ZIC1..3:-0.827519309257;ZBTB6:-0.832006290003;AR:-0.836106440641;LMO2:-0.847187927459;TAL1_TCF{3,4,12}:-0.85211219407;NHLH1,2:-0.853859848886;STAT1,3:-0.859137620624;bHLH_family:-0.898221613912;HNF1A:-0.908652109531;TFCP2:-0.91802017272;XBP1:-0.941301900207;MZF1:-0.945011028782;MAZ:-0.949245696094;ZNF423:-0.967234637754;OCT4_SOX2{dimer}:-1.01428072772;UFEwm:-1.01485789629;CRX:-1.02152258441;NR1H4:-1.02153824151;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.02912951523;RXR{A,B,G}:-1.05007216229;HSF1,2:-1.05010866278;NKX2-2,8:-1.05287699359;YY1:-1.05311195755;SOX{8,9,10}:-1.05626513862;SP1:-1.06590708063;HIC1:-1.06710377981;TEF:-1.09981985923;GATA4:-1.19764071778;POU1F1:-1.20724756815;MEF2{A,B,C,D}:-1.21471946916;FOXA2:-1.23283958302;GFI1:-1.2360710295;ESRRA:-1.24124665879;ALX1:-1.35362062522;HAND1,2:-1.38566521526;ZNF143:-1.39066722938;CDC5L:-1.3914062898;PAX8:-1.41642477211;POU6F1:-1.42189022527;ZNF148:-1.42767132531;SOX17:-1.42969924446;TP53:-1.45484139194;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.46487474224;TBP:-1.46731864321;ARID5B:-1.5066477982;MYBL2:-1.53387993299;HOX{A5,B5}:-1.54678723343;ZNF238:-1.62247196009;LHX3,4:-1.6535159443;XCPE1{core}:-1.65606600463;POU5F1:-1.73349123388;NR6A1:-1.7673186003;GTF2I:-1.79426404188;NKX2-3_NKX2-5:-1.82206607823;ONECUT1,2:-1.82748857802;POU3F1..4:-1.8834677753;GTF2A1,2:-1.88515029679;TEAD1:-1.90488272891;EN1,2:-1.91831591472;GFI1B:-2.08695011236;GZF1:-2.1061156402;TLX1..3_NFIC{dimer}:-2.15773851504;VSX1,2:-2.23330776665;PRDM1:-2.23777275743;ESR1:-2.34897518172;HOX{A4,D4}:-2.36637102338;EBF1:-2.37045995855;NKX3-2:-2.37223378396;KLF4:-2.41535145488;IKZF1:-2.44470329053;ADNP_IRX_SIX_ZHX:-2.82465441058;PAX1,9:-3.42913110453;NR3C1:-3.97627987022
|top_motifs=RORA:4.15651858328;T:3.70352324958;ATF4:3.66970768154;RFX2..5_RFXANK_RFXAP:3.5481318577;RUNX1..3:3.47038298513;CREB1:3.45525311346;PAX3,7:3.38917284335;ATF5_CREB3:3.33092805291;BPTF:2.98501587596;PITX1..3:2.97364388905;FOX{D1,D2}:2.96592390538;FOXP1:2.91730708309;NFKB1_REL_RELA:2.87506601897;FOXN1:2.51124031305;FOXO1,3,4:2.39132005603;ELF1,2,4:2.3837213114;DMAP1_NCOR{1,2}_SMARC:2.35166157424;ZBTB16:2.33473478236;PAX2:2.2811130744;RFX1:2.24102100516;ETS1,2:2.19189517297;FOX{F1,F2,J1}:2.11397797553;NKX2-1,4:2.0723335581;HMX1:2.05164485722;TBX4,5:2.01643870732;JUN:2.00118169184;TOPORS:1.85916048076;SPI1:1.7585223761;NKX6-1,2:1.73574882005;IKZF2:1.63529606383;TGIF1:1.62188185941;TLX2:1.54026349419;ATF6:1.39349830042;ZNF384:1.28054819895;IRF1,2:1.23189523634;ATF2:1.18648520394;SPIB:1.13334420694;FOX{I1,J2}:1.09760769471;BREu{core}:1.07875190175;HIF1A:1.03888330836;NANOG{mouse}:0.914716526608;LEF1_TCF7_TCF7L1,2:0.885068498108;PPARG:0.86834396739;FOSL2:0.755849156242;SMAD1..7,9:0.70596571432;EGR1..3:0.663321010975;FOS_FOS{B,L1}_JUN{B,D}:0.650264013258;MAFB:0.630982289417;EP300:0.600633504986;AIRE:0.600628617159;MYB:0.594001212882;PAX4:0.572483223935;CDX1,2,4:0.551317492613;HBP1_HMGB_SSRP1_UBTF:0.456044322495;ELK1,4_GABP{A,B1}:0.446250319862;PAX6:0.442571135295;TFDP1:0.381572022578;SREBF1,2:0.367909059392;RXRA_VDR{dimer}:0.34521345814;NFATC1..3:0.335530357783;BACH2:0.328600496937;FOXD3:0.30916545634;RREB1:0.282657881586;SOX2:0.26747947606;NKX3-1:0.25814082924;FOXP3:0.249457002819;FOXL1:0.228536830743;HMGA1,2:0.221083384826;GCM1,2:0.214347283464;STAT2,4,6:0.195854507317;NFIL3:0.18410192986;GATA6:0.183480128925;NFE2:0.143499432271;MYFfamily:0.127509906273;NFE2L1:0.0924848319046;HOX{A6,A7,B6,B7}:0.0889115752303;IRF7:-0.0193834572831;SOX5:-0.0224842294042;AHR_ARNT_ARNT2:-0.0823799675095;NFY{A,B,C}:-0.102939309832;PDX1:-0.159155796531;POU2F1..3:-0.193326923719;HES1:-0.224520198739;EVI1:-0.225561772231;DBP:-0.252688268492;FOXQ1:-0.255776013989;FOXM1:-0.26521706905;NFIX:-0.26747824847;TFAP4:-0.279689208073;NFE2L2:-0.294309985026;E2F1..5:-0.317798271484;SNAI1..3:-0.330861203689;CEBPA,B_DDIT3:-0.335625636665;MTE{core}:-0.349627975912;PBX1:-0.351431953024;NR5A1,2:-0.359556734301;CUX2:-0.37067892758;ZEB1:-0.385609125073;SRF:-0.39701031046;GLI1..3:-0.400019637883;HOXA9_MEIS1:-0.413736319655;MTF1:-0.418926536665;MED-1{core}:-0.436829979538;ZFP161:-0.555242138741;HNF4A_NR2F1,2:-0.56638865527;NRF1:-0.569790702558;STAT5{A,B}:-0.569982868138;SPZ1:-0.572614340063;MYOD1:-0.58448722168;TFAP2B:-0.585253987136;PATZ1:-0.615161902532;HLF:-0.628433433405;REST:-0.683242106167;PRRX1,2:-0.695058821721;NANOG:-0.730366257112;PAX5:-0.7512870846;TFAP2{A,C}:-0.752808176195;RBPJ:-0.777554109645;ALX4:-0.786980258749;ZIC1..3:-0.827519309257;ZBTB6:-0.832006290003;AR:-0.836106440641;LMO2:-0.847187927459;TAL1_TCF{3,4,12}:-0.85211219407;NHLH1,2:-0.853859848886;STAT1,3:-0.859137620624;bHLH_family:-0.898221613912;HNF1A:-0.908652109531;TFCP2:-0.91802017272;XBP1:-0.941301900207;MZF1:-0.945011028782;MAZ:-0.949245696094;ZNF423:-0.967234637754;OCT4_SOX2{dimer}:-1.01428072772;UFEwm:-1.01485789629;CRX:-1.02152258441;NR1H4:-1.02153824151;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.02912951523;RXR{A,B,G}:-1.05007216229;HSF1,2:-1.05010866278;NKX2-2,8:-1.05287699359;YY1:-1.05311195755;SOX{8,9,10}:-1.05626513862;SP1:-1.06590708063;HIC1:-1.06710377981;TEF:-1.09981985923;GATA4:-1.19764071778;POU1F1:-1.20724756815;MEF2{A,B,C,D}:-1.21471946916;FOXA2:-1.23283958302;GFI1:-1.2360710295;ESRRA:-1.24124665879;ALX1:-1.35362062522;HAND1,2:-1.38566521526;ZNF143:-1.39066722938;CDC5L:-1.3914062898;PAX8:-1.41642477211;POU6F1:-1.42189022527;ZNF148:-1.42767132531;SOX17:-1.42969924446;TP53:-1.45484139194;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.46487474224;TBP:-1.46731864321;ARID5B:-1.5066477982;MYBL2:-1.53387993299;HOX{A5,B5}:-1.54678723343;ZNF238:-1.62247196009;LHX3,4:-1.6535159443;XCPE1{core}:-1.65606600463;POU5F1:-1.73349123388;NR6A1:-1.7673186003;GTF2I:-1.79426404188;NKX2-3_NKX2-5:-1.82206607823;ONECUT1,2:-1.82748857802;POU3F1..4:-1.8834677753;GTF2A1,2:-1.88515029679;TEAD1:-1.90488272891;EN1,2:-1.91831591472;GFI1B:-2.08695011236;GZF1:-2.1061156402;TLX1..3_NFIC{dimer}:-2.15773851504;VSX1,2:-2.23330776665;PRDM1:-2.23777275743;ESR1:-2.34897518172;HOX{A4,D4}:-2.36637102338;EBF1:-2.37045995855;NKX3-2:-2.37223378396;KLF4:-2.41535145488;IKZF1:-2.44470329053;ADNP_IRX_SIX_ZHX:-2.82465441058;PAX1,9:-3.42913110453;NR3C1:-3.97627987022
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11311-117C6;search_select_hide=table117:FF:11311-117C6
}}
}}

Latest revision as of 16:32, 3 June 2020

Name:Natural Killer Cells, donor2
Species:Human (Homo sapiens)
Library ID:CNhs11957
Sample type:primary cells
Genomic View: UCSC
RefEX:Specific genes
FANTOM CAT:1, 2, 3, 4
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stage57 years old adult
sexmale
age57
cell typenatural killer cell
cell lineNA
company3HBiomedical
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNK726
catalog number3H100-50-10
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005177
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs11957 CAGE DRX008371 DRR009243
Accession ID Hg19

Library idBAMCTSS
CNhs11957 DRZ000668 DRZ002053
Accession ID Hg38

Library idBAMCTSS
CNhs11957 DRZ012018 DRZ013403
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload

RNA-Seq Accession numbers
MethodSample accession id
sRNA-Seq  SAMD00005177
Library accession numbers

Library idMethodExp. accession idRun accession id
SRhi10013.GTTTCG sRNA-Seq DRX037222 DRR041588
Accession ID Hg19

Library idBAMCTSS
SRhi10013.GTTTCG DRZ007230


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0.217
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0.0848
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma-0.25
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
C116-myeloma-xeroderma-tonsil-CD19-spleen-lymph-trachea0
C117-serous-clear-kidney-neuroectodermal-mesothelioma-endometrial-Intestinal0
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C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0.725
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11957

Jaspar motifP-value
MA0002.24.49468e-6
MA0003.10.342
MA0004.10.771
MA0006.10.25
MA0007.10.326
MA0009.10.0118
MA0014.10.676
MA0017.10.069
MA0018.22.87007e-10
MA0019.10.724
MA0024.10.753
MA0025.10.135
MA0027.10.501
MA0028.10.0456
MA0029.10.649
MA0030.10.014
MA0031.11.06832e-4
MA0035.20.618
MA0038.10.0481
MA0039.20.217
MA0040.10.743
MA0041.10.247
MA0042.10.634
MA0043.11.82964e-4
MA0046.10.0284
MA0047.20.688
MA0048.10.56
MA0050.12.4198e-6
MA0051.10.0224
MA0052.10.0564
MA0055.10.662
MA0057.10.166
MA0058.10.741
MA0059.10.57
MA0060.10.0551
MA0061.11.58873e-16
MA0062.25.86746e-10
MA0065.20.86
MA0066.10.619
MA0067.17.22827e-4
MA0068.10.605
MA0069.10.963
MA0070.10.448
MA0071.10.718
MA0072.10.0435
MA0073.10.547
MA0074.10.909
MA0076.10.0225
MA0077.10.147
MA0078.10.876
MA0079.20.783
MA0080.23.15123e-10
MA0081.10.0102
MA0083.10.478
MA0084.10.254
MA0087.10.5
MA0088.10.206
MA0090.11.58917e-4
MA0091.10.251
MA0092.10.76
MA0093.10.668
MA0099.20.17
MA0100.10.966
MA0101.15.29404e-12
MA0102.20.582
MA0103.10.503
MA0104.20.861
MA0105.12.26145e-11
MA0106.10.057
MA0107.12.20756e-11
MA0108.24.52069e-4
MA0111.10.331
MA0112.20.22
MA0113.10.239
MA0114.10.154
MA0115.10.0964
MA0116.10.111
MA0117.10.0119
MA0119.10.327
MA0122.10.707
MA0124.10.0671
MA0125.10.068
MA0131.10.0599
MA0135.10.138
MA0136.14.11708e-15
MA0137.20.203
MA0138.20.0283
MA0139.10.93
MA0140.10.97
MA0141.10.176
MA0142.10.0904
MA0143.10.0955
MA0144.10.538
MA0145.10.0288
MA0146.10.592
MA0147.10.829
MA0148.10.979
MA0149.10.772
MA0150.10.0779
MA0152.10.00683
MA0153.10.0658
MA0154.10.986
MA0155.10.182
MA0156.17.68695e-11
MA0157.10.00692
MA0159.10.925
MA0160.10.888
MA0162.10.293
MA0163.10.025
MA0164.10.52
MA0258.10.855
MA0259.10.739



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs11957

Novel motifP-value
10.994
100.00862
1000.688
1010.341
1020.939
1030.512
1040.791
1050.718
1060.159
1070.0806
1080.613
1090.894
110.835
1100.417
1110.554
1120.832
1130.178
1140.94
1150.385
1160.175
1170.0075
1180.41
1190.575
120.651
1200.269
1210.454
1220.889
1234.95687e-6
1240.808
1250.643
1260.684
1270.301
1280.911
1290.182
130.508
1300.238
1310.405
1320.196
1330.276
1340.771
1350.292
1360.784
1370.0754
1380.842
1390.202
140.453
1400.737
1410.725
1420.248
1430.0375
1440.936
1450.708
1460.413
1470.0301
1480.415
1490.184
150.325
1500.975
1510.366
1520.994
1530.483
1540.102
1550.0628
1560.672
1570.773
1580.023
1590.405
160.209
1600.0524
1610.639
1620.0332
1630.753
1640.0758
1650.766
1660.422
1670.106
1680.504
1690.304
170.7
180.725
190.0676
20.108
200.111
210.896
220.221
230.901
240.455
250.175
260.936
270.422
280.344
290.118
30.669
300.046
310.562
320.0186
330.503
340.297
350.373
360.114
370.45
380.633
390.519
40.974
400.928
410.159
420.506
430.546
440.597
450.0982
460.998
470.876
480.923
490.183
50.614
500.44
510.947
520.865
530.224
540.977
550.538
560.798
570.88
580.178
590.19
60.937
600.581
610.309
620.331
630.749
640.912
650.539
660.271
670.44
680.769
690.934
70.686
700.292
710.238
720.441
730.424
740.627
750.0412
760.0946
770.00238
780.859
790.535
80.267
800.086
810.887
820.694
830.787
840.066
850.704
860.0354
870.976
880.901
890.00379
90.764
900.911
910.748
920.971
930.834
940.325
950.156
960.837
970.266
980.608
996.69795e-6



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs11957


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000623 (natural killer cell)

FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000119 (human natural killer cell sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)

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