FF:11792-124C1: Difference between revisions
From FANTOM5_SSTAR
(Created page with "{{f5samples
|id=FF:11792-124C1
|name=CD4+CD25-CD45RA- naive conventional T cells expanded, donor1
|sample_id=11792
|rna_tube_id=124C1
|rna_box=124
|rna_position=C1
|sam...") |
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004924 | ||
| | |accession_numbers=CAGE;DRX008193;DRR009065;DRZ000490;DRZ001875;DRZ011840;DRZ013225 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001 | ||
|comment=Previously: CD4-positiveCD25-CD45RA- naive conventional T cells expanded, donor1. TODO: full classification | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:231090433..231090469,+!p1@SP140!1.88!74.56!SP140;;chr7:50343634..50343717,+!p2@IKZF1!1.80!61.64!IKZF1;;chr2:192015701..192015743,-!p1@STAT4!1.68!63.11!STAT4;;chr2:192015750..192015793,-!p2@STAT4!1.61!52.46!STAT4;;chr4:57522598..57522664,-!p3@HOPX!1.59!37.62!HOPX;;chr4:57522674..57522699,-!p5@HOPX!1.57!36.49!HOPX;;chr2:231090471..231090504,+!p2@SP140!1.57!35.92!SP140;;chr20:50159198..50159299,-!p1@NFATC2!1.54!48.27!NFATC2;;chr7:50344251..50344288,+!p3@IKZF1!1.53!32.63!IKZF1;;chr9:117150254..117150271,-!p1@AKNA!1.50!81.47!AKNA;;chr10:8096631..8096660,+!p1@GATA3!1.50!36.49!GATA3;;chr10:8096772..8096787,+!p2@GATA3!1.50!35.69!GATA3;;chr14:75988771..75988826,+!p1@BATF!1.47!37.62!BATF;;chr3:18486354..18486377,-!p2@SATB1!1.47!35.24!SATB1;;chr7:50344289..50344323,+!p1@IKZF1!1.46!27.87!IKZF1;;chr7:50348268..50348366,+!p4@IKZF1!1.45!27.31!IKZF1;;chrY:21906594..21906622,-!p1@KDM5D!1.43!26.06!KDM5D;;chr4:109087445..109087463,-!p1@LEF1!1.40!24.25!LEF1;;chr6:391743..391759,+!p1@IRF4!1.39!23.46!IRF4;;chr7:50343895..50343936,+!p5@IKZF1!1.38!23.12!IKZF1;;chr16:68119324..68119364,+!p1@NFATC3!1.37!96.88!NFATC3;;chr3:63953435..63953499,+!p1@ATXN7!1.37!22.66!ATXN7;;chr3:18480217..18480239,-!p3@SATB1!1.36!21.87!SATB1;;chr4:57522166..57522260,-!p2@HOPX!1.35!24.59!HOPX;;chr1:23857698..23857733,-!p1@E2F2!1.31!35.35!E2F2;;chr17:45810594..45810608,+!p1@TBX21!1.28!18.13!TBX21;;chr17:37934365..37934387,-!p2@IKZF3!1.24!16.54!IKZF3;;chr19:16435625..16435682,+!p1@KLF2!1.22!488.59!KLF2;;chr1:25291475..25291511,-!p2@RUNX3!1.22!15.64!RUNX3;;chr13:41593425..41593480,-!p1@ELF1!1.20!93.93!ELF1;;chr19:19779619..19779670,+!p1@ZNF101!1.17!38.87!ZNF101;;chr1:25256756..25256774,-!p1@RUNX3!1.17!25.95!RUNX3;;chr20:56195474..56195506,-!p1@ZBP1!1.14!12.80!ZBP1;;chr11:128563948..128564003,+!p1@FLI1!1.13!149.57!FLI1;;chr16:79634624..79634642,-!p1@MAF!1.13!49.29!MAF;;chr16:79634595..79634620,-!p2@MAF!1.13!22.66!MAF;;chr4:57522513..57522548,-!p4@HOPX!1.13!12.58!HOPX;;chr16:88752889..88752921,-!p1@SNAI3!1.11!14.05!SNAI3;;chr7:77428066..77428132,+!p2@PHTF2!1.10!75.12!PHTF2;;chr19:19729477..19729542,-!p1@PBX4!1.10!24.93!PBX4;;chr1:92951607..92951661,-!p1@GFI1!1.09!11.44!GFI1;;chr17:38020392..38020477,-!p1@IKZF3!1.06!10.42!IKZF3;;chr15:60884706..60884743,-!p1@RORA!1.04!52.80!RORA;;chr6:15249128..15249177,+!p4@JARID2!1.03!17.68!JARID2;;chr7:137620650..137620677,-!p3@CREB3L2!1.03!9.74!CREB3L2;;chr11:47236584..47236679,+!p1@DDB2!1.00!99.37!DDB2;;chr12:56415246..56415286,+!p2@IKZF4!1.00!9.06!IKZF4;;chr2:231090344..231090361,-!p3@SP110!1.00!8.95!SP110;;chr6:45390269..45390298,+!p5@RUNX2!0.99!14.84!RUNX2;;chr6:106546808..106546833,+!p3@PRDM1!0.98!10.76!PRDM1;;chr14:75988831..75988847,+!p2@BATF!0.98!8.61!BATF;;chr3:27763807..27763822,-!p1@EOMES!0.98!8.50!EOMES;;chr1:158978768..158978800,+!p8@IFI16!0.97!8.27!IFI16;;chrY:2803415..2803468,+!p1@ZFY!0.97!8.27!ZFY;;chr21:36421535..36421610,-!p2@RUNX1!0.96!30.03!RUNX1;;chr17:38020516..38020544,-!p5@IKZF3!0.96!8.04!IKZF3;;chr11:128392085..128392232,-!p1@ETS1!0.94!265.60!ETS1;;chr10:35484053..35484076,+!p1@CREM!0.93!19.38!CREM;;chr17:37934204..37934241,-!p3@IKZF3!0.93!7.59!IKZF3;;chr6:45390300..45390335,+!p4@RUNX2!0.92!11.67!RUNX2;;chr20:52226313..52226350,-!p3@ZNF217!0.92!7.25!ZNF217;;chr7:64838786..64838809,+!p2@ZNF92!0.91!42.15!ZNF92;;chr1:158979686..158979745,+!p1@IFI16!0.90!236.48!IFI16;;chr16:88752861..88752884,-!p2@SNAI3!0.90!7.03!SNAI3;;chr8:60031619..60031676,-!p1@TOX!0.89!15.07!TOX;;chr21:36421147..36421193,-!p10@RUNX1!0.89!6.80!RUNX1;;chr2:70142232..70142251,+!p1@MXD1!0.88!38.87!MXD1;;chr2:238600933..238600985,+!p3@LRRFIP1!0.88!37.96!LRRFIP1;;chr7:21467802..21467840,+!p3@SP4!0.88!14.05!SP4;;chr3:18487057..18487105,-!p4@SATB1!0.88!6.57!SATB1;;chr3:71179699..71179744,-!p2@FOXP1!0.87!51.22!FOXP1;;chr10:8095593..8095625,+!p3@GATA3!0.87!7.59!GATA3;;chr7:137620684..137620711,-!p4@CREB3L2!0.87!6.35!CREB3L2;;chr20:56195525..56195556,-!p2@ZBP1!0.87!6.35!ZBP1;;chr21:36421347..36421380,-!p8@RUNX1!0.86!6.23!RUNX1;;chr4:57522701..57522712,-!p10@HOPX!0.85!6.01!HOPX;;chr4:185395633..185395651,-!p2@IRF2!0.83!9.52!IRF2;;chrX:49121165..49121179,-!p1@FOXP3!0.81!5.44!FOXP3;;chr16:68118689..68118733,+!p3@NFATC3!0.80!14.28!NFATC3;;chr17:1959369..1959388,+!p2@HIC1!0.79!14.62!HIC1;;chr4:109088940..109089037,-!p4@LEF1!0.79!5.10!LEF1;;chr6:106546731..106546755,+!p5@PRDM1!0.79!5.10!PRDM1;;chr7:50343864..50343888,+!p7@IKZF1!0.78!4.99!IKZF1;;chr17:38020557..38020572,-!p4@IKZF3!0.78!4.99!IKZF3;;chr2:231084659..231084721,-!p1@SP110!0.77!126.91!SP110;;chr11:128392273..128392308,-!p2@ETS1!0.77!22.55!ETS1;;chr13:41593493..41593506,-!p8@ELF1!0.77!4.87!ELF1;;chrY:21906623..21906637,-!p3@KDM5D!0.77!4.87!KDM5D;;chrX:56258844..56258882,+!p1@KLF8!0.76!6.80!KLF8;;chr4:109089901..109089930,-!p3@LEF1!0.75!4.65!LEF1;;chr5:133450365..133450444,+!p1@TCF7!0.74!22.89!TCF7;;chr5:321810..321877,+!p1@AHRR!0.74!15.64!AHRR;;chr13:74708246..74708264,-!p8@KLF12!0.74!5.10!KLF12;;chr5:176738887..176738934,-!p1@MXD3!0.73!32.18!MXD3;;chr16:6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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000084;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000542;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000624;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000789;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000893;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 67: | Line 40: | ||
|fonse_treatment=EFO:0000369,FF:0000409,FF:0011121,FF:11792-124C1 | |fonse_treatment=EFO:0000369,FF:0000409,FF:0011121,FF:11792-124C1 | ||
|fonse_treatment_closure=EFO:0000369,FF:0000409,FF:0011121,FF:11792-124C1 | |fonse_treatment_closure=EFO:0000369,FF:0000409,FF:0011121,FF:11792-124C1 | ||
|has_quality= | |||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA-%2520memory%2520conventional%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13215.11792-124C1.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA-%2520memory%2520conventional%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13215.11792-124C1.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA-%2520memory%2520conventional%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13215.11792-124C1.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA-%2520memory%2520conventional%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13215.11792-124C1.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD4%252bCD25-CD45RA-%2520memory%2520conventional%2520T%2520cells%2520expanded%252c%2520donor1.CNhs13215.11792-124C1.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11792-124C1 | |||
|is_a=EFO:0002091;;FF:0000002;;FF:0000210 | |||
|is_obsolete= | |||
|library_id=CNhs13215 | |||
|library_id_phase_based=2:CNhs13215 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11792 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11792 | |||
|name=CD4+CD25-CD45RA- memory conventional T cells expanded, donor1 | |||
|namespace= | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13215,LSID1005,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.0649540393283664,0.127081471617318,-0.0237417821130644,-0.117898621850959,0,0,0,0,0,0,0,0,0,0,0.225272069414753,0.127081471617318,0,-0.106707156741247,0,0,0,0,0.162336557453348,-0.0979578962680575,0,0,-0.0863407361716813,0,0,0,0,0,0,0,0,0,0,0,0,-0.114372215021295,0,0,0,0,0,0,0,0,0.151528791841067,0,0,0,0,0,-0.0487054518127182,0.0466158536071809,-0.00828278512218507,0,0,0.0297378444042214,0,0,0,0,0,0,0,0,0,0,0.528851962016284,0,0,0,0,0,0,0,0.0233079268035905,0,0,0,0,-0.0394945576400552,-0.182924144179966,0.0233079268035905,0,0,-0.162770274334659,-0.00145996500791255,0.0233079268035905,0,0.063540735808659,0,0.096907998575302,-0.041005525894391,0,0,0,0,0,0.0233079268035905,0,0,0,0,0,0,0,0,0,0,0,0.0395703675885057,0,0,0,-0.038407315276227,-0.0770180837217326,0,0.0466158536071809,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.0466158536071809,0.096907998575302,0,0,0.08870957612042,0,0.0466158536071809,0,0.0466158536071809,0,0,0,0,-0.200563021678384,0,-0.474086218752008,-0.0548055664030518,0,0,-0.162565216218474,0,0,0,0,0.0466158536071809,0,0.0466158536071809,0.0466158536071809,0,-0.0815040133453838,0,-0.0504125515893149,0,0.194943349813009,0.0875658918888314,0,0,0.0235376465535589,0,-0.129903273089299,-0.0683442610773682,0,0,0,0,-0.0364199177701002,0,0.18442546188136,-0.0827201683234173,0,-0.659323774591857,0.0802768127249383,0,0,0,-0.487451104829546,-0.85604235593954,0,0,0.300936467327927,0.452973856867733,0.0233079268035905,0,-0.391044581551635,0,-0.435059347040027,-0.101738536243027,0,-0.0205487740005545,0,0,0,0,0.04435478806021,0,0,0,0,0,0,-0.0574934668214365,-0.0733682465985193,0,0,0,0,0.0577097027252531,0,0,-0.326670302349386,-0.262026437176439,0.0898469126344425,-0.595185303194834,0,-0.302389727009913,-0.431515588279497,-0.389233603152377,-0.223647468302971,-0.147401849371139,-0.189981719549847,-0.109517145481824,-0.182924144179966,-0.243098221987583,-0.0307866237871313,-0.0813887491256005,0,-1.2314085082871,0.0809665408463238,0,0,0,0.705471811067403,0,0,0.0530596926496547,-0.184829300598112,-0.624371582868529,-0.736791969329089,-0.375484404353327,-0.123407180205825,-0.0395325284566706,-0.232164383481842,-0.00158280990627746,-0.4215723249037,-0.127314249781762,0.0466158536071809,-0.0615254922529047,-0.0638362270784927,0.240674026560077,0.728085118252314,0,-0.321640904357632,0.0587372105399502,0,-0.878546761689074,-0.0253733389083313,0,0,-0.0800701320613142,0,0,0,0,0,-0.0394945576400552,0.305940495129436,0.179828509822751,0,0.0405875988377377,-0.0064202338085792,0.273506098654108,0,0.0843700800077065,0,0,0.138479335735879,0,-0.113310746876401,-0.323802847179382,-0.164990696339003,-0.049535783623006,0.0686346448054932,0.348383695266874,0.208167932818354,-0.162770274334659,0.395097565106295,-0.102640143825137,-0.0881268324752877,0.0466158536071809,-0.287382946963011,0.382623703129776,-0.0926799547384711,-0.241094214391677,0,0.19510010137951,0,-0.0177472202680183,0.0233079268035905,0.284301081051051,-0.188946125565436,1.06649475197117,0.0829692324690012,0,-0.119842484241696,-0.788130937773974,0,-0.152302465086953,-0.0366680684064415,0.162336557453348,-0.150367083334639,-0.651080112905402,0.298919977388652,-0.138989456679195,0,-0.743464304782476,0,0,-0.103295150351581,0.0447550180216111,0.0466158536071809,-0.167406783591309,-0.000746175085210687,-0.0753640791790106,0.0463654840184143,0.127081471617318,0,-0.599084484385544,0,0.0466158536071809,-0.559312210210849,-0.107000622465109,-0.170621391075833,0.317149373833001,-0.0052094856478272,-0.108622809454255,0,0,-0.177527765965176,1.40027698883401,-0.140971653069687,0,0,-0.10517228206349,0,0,0,0,-0.09779401565126,0,0.0466158536071809,0,0,0,0,0,0.200371860178762,-0.159889980403439,0,-0.179576135656249,0,0,0,0,0,0.0713580778561211,0,0,-0.00299213023557754,-0.00108437923310545,0.0719259341365882,0,0,0.0233079268035905,0,0.135764223354329,0.14825106381308,0.08870957612042,-0.00478123488031335,0,0.112636034707377,0,0.0466158536071809,-0.0861409897892114,0,0,0,0.063540735808659,0.0309791190667561,-0.112366855971889,0,0,0,-0.0820110517887819,0.0466158536071809,0,0,0,0.116426824359125,0,0,-0.32662522771128,0,-0.170508201661194,0.00712769657357863,0,0.274445079422614,0.382922783953206,-1.02938928486246,0,0,-0.172637555669467,0,0,0.235345530616464,0,0,0,0,0,0,0,0.141480291109213,0.127081471617318,0.554493850399104,0,0,0,0,0,0,0,0,0,0,0,0.0591807675588838,0.070112500794838,0,0,0,0,0,0,0,-0.0241060230789031,0.0977324393289753,0.0332845637720321,0,0,0,0,0,0,0,-0.119938313755438,0,0,0.162336557453348,0,0,-0.00828278512218507,0,0.08870957612042,0,0,-0.235797243701918,0,0,-0.0237417821130644,0,0,0,0,0,0,0,0,0,0,0,0,0,0.228168539872356,0.00281901100119897,0,0,0,0,0,0.127081471617318,0,-0.112496740752742,0,0,0,0,1.87881370247014,0,0,0,-0.104796384789156,0,0.0649540393283664,0,0,0.25362035008045,0,0,0.08870957612042,0,0,0,0,0.08870957612042,0,0,0,0,0,0,0.04435478806021,0,0,0,-0.326334244170654,-0.0247755787802223,-0.0778377219060358,0.0975228077256673,0,0,-0.232628352633041,0,0,0,0,0,0,0.066131250877977,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0466158536071809,0,0,0,0,0,0,0,0,0,0,0,0.0361037474215894,0,0,0,0,0,0,0,-0.0979578962680575,0,0,-0.0920328098005262,0,0,0,0,0,0,-0.243622052596499,-0.238865611762938,-0.156851793382151,0,0,0,-0.054385572482455,0,0,-0.0482120461578062,0.0466158536071809,0.0219321887015187,0,0,0,0,0,0,0,0,0,0,0,0,0.0676627148638005,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.106707156741247,0,0,0,0,0,0,0,0,0,0,0,0,0.04435478806021,0,0,0,0,0,0.144709014535333,0,0,0,0,0,0,0.08870957612042,0.0466158536071809,0,0.0233079268035905,0,0,0,0,0,0,0.116106738568399,0.0466158536071809,0,0,0.0466158536071809,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.162336557453348,-0.0800184682686384,0,0,0,-0.0860047580397253,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.194943349813009,0,0,0,0,0,0,0,0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| |||
|rna_box=124 | |||
|rna_catalog_number= | |||
|rna_concentration=0.3219 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=13 | |||
|rna_od260/230=1.89 | |||
|rna_od260/280=2.01 | |||
|rna_position=C1 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=124C1 | |||
|rna_weight_ug=3.219 | |||
|sample_age=25 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=T cell | |||
|sample_collaboration=Michael Rehli (University of Regensberg) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.02775274822625e-245!GO:0043227;membrane-bound organelle;1.8502937860217e-212!GO:0043231;intracellular membrane-bound organelle;5.48544702931722e-212!GO:0043226;organelle;1.33472744921946e-201!GO:0043229;intracellular organelle;8.01711380778146e-201!GO:0005737;cytoplasm;2.96123272406666e-152!GO:0044422;organelle part;2.87636267964446e-141!GO:0044446;intracellular organelle part;1.82336894040187e-139!GO:0005634;nucleus;3.43599803127041e-111!GO:0032991;macromolecular complex;7.32590792164206e-109!GO:0044444;cytoplasmic part;9.56504279842041e-105!GO:0044237;cellular metabolic process;2.84356671083952e-103!GO:0043170;macromolecule metabolic process;1.45886467666815e-102!GO:0044238;primary metabolic process;1.26918145708046e-100!GO:0030529;ribonucleoprotein complex;2.24104492303335e-87!GO:0044428;nuclear part;3.78077092006459e-85!GO:0003723;RNA binding;4.23515908422726e-79!GO:0043233;organelle lumen;7.0412263249297e-70!GO:0031974;membrane-enclosed lumen;7.0412263249297e-70!GO:0043283;biopolymer metabolic process;6.84841371403531e-69!GO:0005515;protein binding;2.8963744797257e-59!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.69135028683305e-58!GO:0043234;protein complex;1.02731014673226e-56!GO:0005739;mitochondrion;1.49157391595285e-56!GO:0010467;gene expression;2.23023755494338e-53!GO:0006396;RNA processing;2.23023755494338e-53!GO:0006412;translation;1.448501578015e-52!GO:0019538;protein metabolic process;4.33415415892572e-52!GO:0033036;macromolecule localization;1.62658510179483e-49!GO:0044267;cellular protein metabolic process;4.77143222597142e-49!GO:0031981;nuclear lumen;7.47225586485304e-49!GO:0005840;ribosome;8.90480077484786e-49!GO:0044260;cellular macromolecule metabolic process;3.6221175862357e-48!GO:0015031;protein transport;1.12631013758044e-47!GO:0006259;DNA metabolic process;1.26111788759412e-47!GO:0016071;mRNA metabolic process;9.19971666507038e-47!GO:0045184;establishment of protein localization;1.36057972496606e-45!GO:0008104;protein localization;1.36057972496606e-45!GO:0003735;structural constituent of ribosome;5.48071578907797e-43!GO:0031090;organelle membrane;1.16026201909021e-41!GO:0031967;organelle envelope;5.39951703801967e-41!GO:0031975;envelope;1.28477383604996e-40!GO:0006397;mRNA processing;1.6423570814135e-40!GO:0044429;mitochondrial part;1.65212565098391e-40!GO:0009059;macromolecule biosynthetic process;2.37829465480893e-40!GO:0008380;RNA splicing;3.75309101886257e-40!GO:0003676;nucleic acid binding;6.23016530932497e-40!GO:0033279;ribosomal subunit;5.20078647657309e-38!GO:0016043;cellular component organization and biogenesis;3.97927377468351e-37!GO:0046907;intracellular transport;4.31904368044627e-36!GO:0005829;cytosol;1.47801774076451e-35!GO:0007049;cell cycle;6.25857960966654e-34!GO:0065003;macromolecular complex assembly;8.04478865271527e-34!GO:0006886;intracellular protein transport;3.11677193333555e-33!GO:0009058;biosynthetic process;5.78175615592091e-33!GO:0044249;cellular biosynthetic process;9.32751462826587e-33!GO:0005654;nucleoplasm;2.90771973059873e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.42189155639455e-32!GO:0006996;organelle organization and biogenesis;7.58790044887276e-32!GO:0043228;non-membrane-bound organelle;8.85517306151066e-32!GO:0043232;intracellular non-membrane-bound organelle;8.85517306151066e-32!GO:0000166;nucleotide binding;2.59872319701156e-31!GO:0005681;spliceosome;4.52239998222429e-30!GO:0022607;cellular component assembly;1.31464895086381e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.34107610823338e-29!GO:0005694;chromosome;1.94409794991823e-28!GO:0006974;response to DNA damage stimulus;3.55477456916009e-28!GO:0016070;RNA metabolic process;7.50796182975952e-27!GO:0022402;cell cycle process;8.44164887719853e-27!GO:0051641;cellular localization;1.2642726697435e-26!GO:0044427;chromosomal part;1.43124621283014e-26!GO:0051649;establishment of cellular localization;1.65827480015169e-26!GO:0005740;mitochondrial envelope;3.12296304912455e-26!GO:0044445;cytosolic part;6.3898274424165e-26!GO:0019866;organelle inner membrane;2.33649287998558e-25!GO:0031966;mitochondrial membrane;5.09949026127426e-25!GO:0051276;chromosome organization and biogenesis;6.20504330380448e-24!GO:0006281;DNA repair;7.72489043808491e-24!GO:0032553;ribonucleotide binding;8.21040392246936e-24!GO:0032555;purine ribonucleotide binding;8.21040392246936e-24!GO:0006512;ubiquitin cycle;8.6111818058495e-24!GO:0044451;nucleoplasm part;9.77062570489515e-24!GO:0000278;mitotic cell cycle;3.7450055971109e-23!GO:0017076;purine nucleotide binding;4.91739240597913e-23!GO:0005743;mitochondrial inner membrane;1.12217238458528e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.62223828667744e-22!GO:0016462;pyrophosphatase activity;4.32986022382644e-22!GO:0016817;hydrolase activity, acting on acid anhydrides;4.63460841334639e-22!GO:0006915;apoptosis;5.74337297896093e-22!GO:0012501;programmed cell death;6.18359255534599e-22!GO:0017111;nucleoside-triphosphatase activity;6.99952109181557e-22!GO:0022618;protein-RNA complex assembly;2.2699934825587e-21!GO:0005524;ATP binding;2.92754860672818e-21!GO:0008219;cell death;4.58359111351326e-21!GO:0016265;death;4.58359111351326e-21!GO:0006119;oxidative phosphorylation;8.44492047432709e-21!GO:0032559;adenyl ribonucleotide binding;1.7525810608285e-20!GO:0044265;cellular macromolecule catabolic process;2.58017577430045e-20!GO:0016874;ligase activity;6.38374687805261e-20!GO:0015935;small ribosomal subunit;8.55382929546086e-20!GO:0043412;biopolymer modification;1.11775429690777e-19!GO:0030554;adenyl nucleotide binding;1.65030190396703e-19!GO:0022403;cell cycle phase;1.90044305245524e-19!GO:0000087;M phase of mitotic cell cycle;3.18499796748699e-19!GO:0015934;large ribosomal subunit;3.37624793684313e-19!GO:0007067;mitosis;6.69365351871823e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;6.91806199752113e-19!GO:0044455;mitochondrial membrane part;1.31454851913527e-18!GO:0006323;DNA packaging;3.83155548311364e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;5.25855239202548e-18!GO:0019941;modification-dependent protein catabolic process;6.09853427026509e-18!GO:0043632;modification-dependent macromolecule catabolic process;6.09853427026509e-18!GO:0009719;response to endogenous stimulus;1.02871640348623e-17!GO:0006511;ubiquitin-dependent protein catabolic process;1.27343198509489e-17!GO:0051301;cell division;1.54295441108565e-17!GO:0044257;cellular protein catabolic process;1.60752141163178e-17!GO:0031980;mitochondrial lumen;1.77997686799586e-17!GO:0005759;mitochondrial matrix;1.77997686799586e-17!GO:0006464;protein modification process;1.92776131467472e-17!GO:0005730;nucleolus;2.79218812659544e-17!GO:0012505;endomembrane system;3.35924185272879e-17!GO:0008135;translation factor activity, nucleic acid binding;5.39875687453792e-17!GO:0043285;biopolymer catabolic process;8.88326560560233e-17!GO:0000279;M phase;1.0210901238333e-16!GO:0000502;proteasome complex (sensu Eukaryota);1.84698601818237e-16!GO:0016604;nuclear body;1.96323588096897e-16!GO:0016887;ATPase activity;1.98956167262206e-16!GO:0042623;ATPase activity, coupled;2.13389851438014e-16!GO:0006605;protein targeting;2.32345927052893e-16!GO:0009057;macromolecule catabolic process;4.63183167002405e-16!GO:0000785;chromatin;5.22774771894678e-16!GO:0005635;nuclear envelope;7.79752920052911e-16!GO:0006457;protein folding;9.62587805339858e-16!GO:0006913;nucleocytoplasmic transport;1.09734996897739e-15!GO:0043687;post-translational protein modification;1.22135548140094e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.22513396044127e-15!GO:0051169;nuclear transport;2.37209621486153e-15!GO:0005746;mitochondrial respiratory chain;2.47170391796518e-15!GO:0051726;regulation of cell cycle;2.59503067556428e-15!GO:0048770;pigment granule;2.64656107916338e-15!GO:0042470;melanosome;2.64656107916338e-15!GO:0006333;chromatin assembly or disassembly;2.87161923863031e-15!GO:0042981;regulation of apoptosis;2.87161923863031e-15!GO:0000074;regulation of progression through cell cycle;4.27067180558663e-15!GO:0043067;regulation of programmed cell death;5.20622390776577e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;7.64823362864841e-15!GO:0008134;transcription factor binding;1.09804922486034e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.53346475299057e-14!GO:0031965;nuclear membrane;1.78259712943722e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;2.05593337367974e-14!GO:0000375;RNA splicing, via transesterification reactions;2.05593337367974e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.05593337367974e-14!GO:0050136;NADH dehydrogenase (quinone) activity;2.44900773791257e-14!GO:0003954;NADH dehydrogenase activity;2.44900773791257e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.44900773791257e-14!GO:0006260;DNA replication;4.27662368088884e-14!GO:0044248;cellular catabolic process;5.85646550176066e-14!GO:0003743;translation initiation factor activity;6.71188233411907e-14!GO:0065004;protein-DNA complex assembly;7.19982022680555e-14!GO:0006413;translational initiation;7.67820652024366e-14!GO:0030163;protein catabolic process;2.19312962802631e-13!GO:0004386;helicase activity;2.69921334556858e-13!GO:0050794;regulation of cellular process;7.07223278427455e-13!GO:0016607;nuclear speck;7.54004297239883e-13!GO:0005761;mitochondrial ribosome;7.5500362848285e-13!GO:0000313;organellar ribosome;7.5500362848285e-13!GO:0042775;organelle ATP synthesis coupled electron transport;1.15018656028109e-12!GO:0042773;ATP synthesis coupled electron transport;1.15018656028109e-12!GO:0044453;nuclear membrane part;1.32244496197033e-12!GO:0030964;NADH dehydrogenase complex (quinone);2.238470052693e-12!GO:0045271;respiratory chain complex I;2.238470052693e-12!GO:0005747;mitochondrial respiratory chain complex I;2.238470052693e-12!GO:0006334;nucleosome assembly;6.59857882084165e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;6.97587079413912e-12!GO:0042254;ribosome biogenesis and assembly;1.03551852181457e-11!GO:0048193;Golgi vesicle transport;1.22307279223667e-11!GO:0006446;regulation of translational initiation;1.60548579970977e-11!GO:0031497;chromatin assembly;1.85264020102457e-11!GO:0008026;ATP-dependent helicase activity;3.22768387827912e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.11337715760098e-11!GO:0008639;small protein conjugating enzyme activity;4.16140446697428e-11!GO:0016568;chromatin modification;4.74649863572367e-11!GO:0051082;unfolded protein binding;5.58973903886071e-11!GO:0019787;small conjugating protein ligase activity;7.66327247438374e-11!GO:0004842;ubiquitin-protein ligase activity;9.13386720707749e-11!GO:0017038;protein import;1.03039469228147e-10!GO:0044432;endoplasmic reticulum part;1.21693086819893e-10!GO:0051186;cofactor metabolic process;1.30996439796303e-10!GO:0005794;Golgi apparatus;1.47763120757701e-10!GO:0006793;phosphorus metabolic process;1.51675415935909e-10!GO:0006796;phosphate metabolic process;1.51675415935909e-10!GO:0043566;structure-specific DNA binding;1.82942737221526e-10!GO:0005643;nuclear pore;1.85985259104333e-10!GO:0050657;nucleic acid transport;2.34471289109923e-10!GO:0051236;establishment of RNA localization;2.34471289109923e-10!GO:0050658;RNA transport;2.34471289109923e-10!GO:0006403;RNA localization;2.86272365278963e-10!GO:0016787;hydrolase activity;2.90621728201958e-10!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.02438728121746e-10!GO:0005783;endoplasmic reticulum;6.55873856811864e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.7517778788106e-10!GO:0003697;single-stranded DNA binding;9.47369112880475e-10!GO:0009259;ribonucleotide metabolic process;1.20672591557917e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.51980184869509e-09!GO:0008565;protein transporter activity;1.70516880183993e-09!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.0403539816981e-09!GO:0019829;cation-transporting ATPase activity;2.70235898831935e-09!GO:0065002;intracellular protein transport across a membrane;3.50586333041309e-09!GO:0009260;ribonucleotide biosynthetic process;4.32822364023347e-09!GO:0016881;acid-amino acid ligase activity;4.34617099491287e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.65255537217859e-09!GO:0006164;purine nucleotide biosynthetic process;4.76493749197457e-09!GO:0006163;purine nucleotide metabolic process;5.38221468805439e-09!GO:0016310;phosphorylation;6.12171293567819e-09!GO:0005789;endoplasmic reticulum membrane;6.20663999516889e-09!GO:0046930;pore complex;6.47922926645311e-09!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;9.57281199768654e-09!GO:0019222;regulation of metabolic process;9.6325587112616e-09!GO:0000775;chromosome, pericentric region;9.81131613836763e-09!GO:0051246;regulation of protein metabolic process;1.21605054610464e-08!GO:0003712;transcription cofactor activity;1.24239169555656e-08!GO:0006732;coenzyme metabolic process;1.28630658697084e-08!GO:0051028;mRNA transport;1.38089510626808e-08!GO:0009152;purine ribonucleotide biosynthetic process;1.41298349930829e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.58488120584369e-08!GO:0009150;purine ribonucleotide metabolic process;1.66157913249307e-08!GO:0005819;spindle;1.73294407054603e-08!GO:0030532;small nuclear ribonucleoprotein complex;2.24963587821638e-08!GO:0016192;vesicle-mediated transport;2.3363619409674e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.53368299165475e-08!GO:0000786;nucleosome;2.56171000994087e-08!GO:0007243;protein kinase cascade;2.83281891887709e-08!GO:0006399;tRNA metabolic process;3.12970568460473e-08!GO:0050789;regulation of biological process;3.21362190756835e-08!GO:0051170;nuclear import;3.93064364968286e-08!GO:0006916;anti-apoptosis;5.27489181273262e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.51143822049964e-08!GO:0016779;nucleotidyltransferase activity;5.74099477888508e-08!GO:0005813;centrosome;6.08744323936256e-08!GO:0004298;threonine endopeptidase activity;6.59784177650983e-08!GO:0016740;transferase activity;6.87824393846665e-08!GO:0006606;protein import into nucleus;6.88130764465599e-08!GO:0032446;protein modification by small protein conjugation;6.96747391620563e-08!GO:0015630;microtubule cytoskeleton;7.0574474866129e-08!GO:0016072;rRNA metabolic process;8.2682679731848e-08!GO:0006310;DNA recombination;8.90191783672378e-08!GO:0006364;rRNA processing;9.33411100480245e-08!GO:0015078;hydrogen ion transmembrane transporter activity;1.03839649571635e-07!GO:0043069;negative regulation of programmed cell death;1.04984286503889e-07!GO:0005815;microtubule organizing center;1.05999487248793e-07!GO:0006917;induction of apoptosis;1.13597161820782e-07!GO:0005768;endosome;1.16065469013937e-07!GO:0015986;ATP synthesis coupled proton transport;1.20003463911135e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.20003463911135e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.46419574365722e-07!GO:0043066;negative regulation of apoptosis;1.46769064732301e-07!GO:0016567;protein ubiquitination;1.83642888877135e-07!GO:0012502;induction of programmed cell death;1.92211525459513e-07!GO:0006888;ER to Golgi vesicle-mediated transport;2.04895487204541e-07!GO:0009056;catabolic process;2.36910201386845e-07!GO:0006261;DNA-dependent DNA replication;2.49326511864501e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.71247460965626e-07!GO:0043065;positive regulation of apoptosis;2.75831936251613e-07!GO:0009055;electron carrier activity;2.75831936251613e-07!GO:0065009;regulation of a molecular function;2.89176839569285e-07!GO:0019899;enzyme binding;3.36489089928208e-07!GO:0048523;negative regulation of cellular process;3.53560066978903e-07!GO:0009060;aerobic respiration;3.9207600043327e-07!GO:0043068;positive regulation of programmed cell death;4.42248982516021e-07!GO:0000245;spliceosome assembly;4.71306154144891e-07!GO:0000075;cell cycle checkpoint;5.23818737411819e-07!GO:0031323;regulation of cellular metabolic process;5.6214657399987e-07!GO:0045786;negative regulation of progression through cell cycle;6.21173660674252e-07!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;7.43974032910836e-07!GO:0004812;aminoacyl-tRNA ligase activity;7.43974032910836e-07!GO:0016875;ligase activity, forming carbon-oxygen bonds;7.43974032910836e-07!GO:0030120;vesicle coat;8.00371779973945e-07!GO:0030662;coated vesicle membrane;8.00371779973945e-07!GO:0009142;nucleoside triphosphate biosynthetic process;8.35214356273924e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;8.35214356273924e-07!GO:0006754;ATP biosynthetic process;9.0929143253069e-07!GO:0006753;nucleoside phosphate metabolic process;9.0929143253069e-07!GO:0051188;cofactor biosynthetic process;1.07190433921589e-06!GO:0043038;amino acid activation;1.10512058939637e-06!GO:0006418;tRNA aminoacylation for protein translation;1.10512058939637e-06!GO:0043039;tRNA aminoacylation;1.10512058939637e-06!GO:0016469;proton-transporting two-sector ATPase complex;1.138809096782e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.33617134214055e-06!GO:0009141;nucleoside triphosphate metabolic process;1.37737184865509e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.44579257940193e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.44579257940193e-06!GO:0048475;coated membrane;1.46340092789802e-06!GO:0030117;membrane coat;1.46340092789802e-06!GO:0051168;nuclear export;1.60964950118523e-06!GO:0006461;protein complex assembly;2.15403036050116e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.27098125175833e-06!GO:0009144;purine nucleoside triphosphate metabolic process;2.27098125175833e-06!GO:0046034;ATP metabolic process;2.30054128206034e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.8738424721041e-06!GO:0006366;transcription from RNA polymerase II promoter;2.91928201580291e-06!GO:0007242;intracellular signaling cascade;3.00826678152718e-06!GO:0045259;proton-transporting ATP synthase complex;3.1091488339331e-06!GO:0005793;ER-Golgi intermediate compartment;3.1091488339331e-06!GO:0045333;cellular respiration;3.22326808558435e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;3.22326808558435e-06!GO:0006613;cotranslational protein targeting to membrane;3.27578845464636e-06!GO:0000151;ubiquitin ligase complex;3.62381177222918e-06!GO:0008632;apoptotic program;3.88120956188109e-06!GO:0051325;interphase;4.44277946690789e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;4.51485033981247e-06!GO:0015399;primary active transmembrane transporter activity;4.51485033981247e-06!GO:0003713;transcription coactivator activity;4.90445072074325e-06!GO:0003690;double-stranded DNA binding;5.25568455609285e-06!GO:0051329;interphase of mitotic cell cycle;5.49813502221002e-06!GO:0048519;negative regulation of biological process;5.81513763990294e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;5.8803092063677e-06!GO:0003724;RNA helicase activity;6.53178181908607e-06!GO:0006350;transcription;7.03030763126166e-06!GO:0016563;transcription activator activity;7.6145868539405e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.16851061654104e-06!GO:0005657;replication fork;8.99319334404257e-06!GO:0004674;protein serine/threonine kinase activity;9.03276241588629e-06!GO:0031324;negative regulation of cellular metabolic process;1.21370518355003e-05!GO:0007088;regulation of mitosis;1.22555229267118e-05!GO:0006099;tricarboxylic acid cycle;1.34809121545996e-05!GO:0046356;acetyl-CoA catabolic process;1.34809121545996e-05!GO:0007005;mitochondrion organization and biogenesis;1.38910311583311e-05!GO:0005525;GTP binding;1.64423682503286e-05!GO:0048522;positive regulation of cellular process;1.85223493649208e-05!GO:0006401;RNA catabolic process;1.88701342553488e-05!GO:0007059;chromosome segregation;2.01914644634406e-05!GO:0016363;nuclear matrix;2.18099679146003e-05!GO:0005773;vacuole;2.53237929561882e-05!GO:0009108;coenzyme biosynthetic process;2.59359562529275e-05!GO:0006752;group transfer coenzyme metabolic process;2.81544197470234e-05!GO:0006084;acetyl-CoA metabolic process;2.98800739944802e-05!GO:0007051;spindle organization and biogenesis;3.18543414193882e-05!GO:0008094;DNA-dependent ATPase activity;3.23770918971568e-05!GO:0006302;double-strand break repair;3.41319586596457e-05!GO:0006612;protein targeting to membrane;3.45082430600426e-05!GO:0043623;cellular protein complex assembly;3.66344205886693e-05!GO:0009117;nucleotide metabolic process;4.84341521201958e-05!GO:0010468;regulation of gene expression;4.84423739250118e-05!GO:0016564;transcription repressor activity;6.0361283630878e-05!GO:0009892;negative regulation of metabolic process;6.15443256776008e-05!GO:0000323;lytic vacuole;6.15952147895341e-05!GO:0005764;lysosome;6.15952147895341e-05!GO:0005852;eukaryotic translation initiation factor 3 complex;6.61174193073784e-05!GO:0003924;GTPase activity;6.6624558808726e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.74716409217391e-05!GO:0008234;cysteine-type peptidase activity;6.94265184320808e-05!GO:0000776;kinetochore;7.13443602249714e-05!GO:0065007;biological regulation;7.28136022538209e-05!GO:0005762;mitochondrial large ribosomal subunit;7.62523166824847e-05!GO:0000315;organellar large ribosomal subunit;7.62523166824847e-05!GO:0005798;Golgi-associated vesicle;8.59947729717584e-05!GO:0043492;ATPase activity, coupled to movement of substances;8.92684833334824e-05!GO:0006402;mRNA catabolic process;9.13745358197034e-05!GO:0051427;hormone receptor binding;9.83566995309805e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000100458552854843!GO:0009109;coenzyme catabolic process;0.00011508075993648!GO:0044431;Golgi apparatus part;0.000124197974145057!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000127429837321997!GO:0005770;late endosome;0.000128026253865104!GO:0050790;regulation of catalytic activity;0.000128026253865104!GO:0007093;mitotic cell cycle checkpoint;0.000130365714332571!GO:0009967;positive regulation of signal transduction;0.000131599721553948!GO:0003899;DNA-directed RNA polymerase activity;0.00013286333181906!GO:0003684;damaged DNA binding;0.000138211902339033!GO:0008186;RNA-dependent ATPase activity;0.000140261003632852!GO:0005885;Arp2/3 protein complex;0.000141713322295085!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000143881663603441!GO:0003677;DNA binding;0.000146855926316123!GO:0006417;regulation of translation;0.000158327266159955!GO:0051187;cofactor catabolic process;0.000158610358612623!GO:0035257;nuclear hormone receptor binding;0.000200600222983557!GO:0044440;endosomal part;0.000201763953765984!GO:0010008;endosome membrane;0.000201763953765984!GO:0005667;transcription factor complex;0.000207340598947775!GO:0003678;DNA helicase activity;0.000209535673304905!GO:0032561;guanyl ribonucleotide binding;0.000211349022111837!GO:0019001;guanyl nucleotide binding;0.000211349022111837!GO:0043021;ribonucleoprotein binding;0.000213405486085408!GO:0030384;phosphoinositide metabolic process;0.000261404220514134!GO:0051052;regulation of DNA metabolic process;0.000287246971940279!GO:0015992;proton transport;0.000293057404169228!GO:0006818;hydrogen transport;0.000300395242433609!GO:0003729;mRNA binding;0.000305256447379498!GO:0004518;nuclease activity;0.000323574127787607!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000325610388152897!GO:0008654;phospholipid biosynthetic process;0.000332027333242798!GO:0008270;zinc ion binding;0.000389414743324699!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000391796837118577!GO:0004004;ATP-dependent RNA helicase activity;0.000425709902900768!GO:0006891;intra-Golgi vesicle-mediated transport;0.000435979548954407!GO:0009615;response to virus;0.000435979548954407!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000437351229631329!GO:0003682;chromatin binding;0.000491512443197294!GO:0031982;vesicle;0.00054897954107946!GO:0005637;nuclear inner membrane;0.000632136897970594!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000646045475272391!GO:0004527;exonuclease activity;0.000663587140040555!GO:0031326;regulation of cellular biosynthetic process;0.000663587140040555!GO:0006650;glycerophospholipid metabolic process;0.000672582015727063!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00067538090290811!GO:0032774;RNA biosynthetic process;0.000689282756794585!GO:0000314;organellar small ribosomal subunit;0.000693699129962958!GO:0005763;mitochondrial small ribosomal subunit;0.000693699129962958!GO:0006289;nucleotide-excision repair;0.000743272814950589!GO:0006611;protein export from nucleus;0.000757179172247908!GO:0016853;isomerase activity;0.00079037097103825!GO:0051252;regulation of RNA metabolic process;0.000800012822821315!GO:0007264;small GTPase mediated signal transduction;0.000839570824641245!GO:0000082;G1/S transition of mitotic cell cycle;0.000859385619775549!GO:0006351;transcription, DNA-dependent;0.000875162773316485!GO:0030658;transport vesicle membrane;0.000890236217476636!GO:0015631;tubulin binding;0.00102615543188125!GO:0006383;transcription from RNA polymerase III promoter;0.00105891541297944!GO:0016481;negative regulation of transcription;0.00106499696651363!GO:0048500;signal recognition particle;0.00108866590434967!GO:0045449;regulation of transcription;0.00112334383438663!GO:0046489;phosphoinositide biosynthetic process;0.0011705865673754!GO:0043681;protein import into mitochondrion;0.00117490197697013!GO:0005769;early endosome;0.00122065974108951!GO:0048518;positive regulation of biological process;0.00125056930711264!GO:0007006;mitochondrial membrane organization and biogenesis;0.00126630194741604!GO:0019867;outer membrane;0.0013266247806218!GO:0042802;identical protein binding;0.00136966133847454!GO:0031988;membrane-bound vesicle;0.0014058008292133!GO:0005741;mitochondrial outer membrane;0.00142793475552784!GO:0047485;protein N-terminus binding;0.00143991738797768!GO:0060090;molecular adaptor activity;0.00153625848234833!GO:0000139;Golgi membrane;0.00154501722700197!GO:0031968;organelle outer membrane;0.00160423810474812!GO:0006352;transcription initiation;0.00160607443221635!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00166066491752998!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00166066491752998!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00166066491752998!GO:0000287;magnesium ion binding;0.00168159247503633!GO:0007052;mitotic spindle organization and biogenesis;0.00171059985745059!GO:0022415;viral reproductive process;0.00179642472736563!GO:0008168;methyltransferase activity;0.00182392911295795!GO:0032259;methylation;0.00182392911295795!GO:0031410;cytoplasmic vesicle;0.00183460841352983!GO:0031072;heat shock protein binding;0.00189561338341059!GO:0019843;rRNA binding;0.00191471221537367!GO:0006414;translational elongation;0.00192423398436098!GO:0008312;7S RNA binding;0.00193010455224216!GO:0016741;transferase activity, transferring one-carbon groups;0.001996592119332!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00216498629674427!GO:0045047;protein targeting to ER;0.00216498629674427!GO:0000209;protein polyubiquitination;0.00235887295572816!GO:0016251;general RNA polymerase II transcription factor activity;0.00236094334025974!GO:0030660;Golgi-associated vesicle membrane;0.00258249032549473!GO:0016197;endosome transport;0.00263677108299211!GO:0005048;signal sequence binding;0.00270185249568629!GO:0000922;spindle pole;0.00270353266402415!GO:0006405;RNA export from nucleus;0.00274987305826855!GO:0046474;glycerophospholipid biosynthetic process;0.00274987305826855!GO:0005684;U2-dependent spliceosome;0.00291494000310518!GO:0007265;Ras protein signal transduction;0.00293581949905898!GO:0006607;NLS-bearing substrate import into nucleus;0.00301544095187289!GO:0001772;immunological synapse;0.00301544095187289!GO:0006338;chromatin remodeling;0.00309435508185638!GO:0042110;T cell activation;0.00309679829582855!GO:0003711;transcription elongation regulator activity;0.00311583329034976!GO:0007050;cell cycle arrest;0.00316503288278191!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00327563636236734!GO:0000228;nuclear chromosome;0.00327563636236734!GO:0051092;activation of NF-kappaB transcription factor;0.00332026539860246!GO:0051087;chaperone binding;0.00332356018611776!GO:0006497;protein amino acid lipidation;0.00338136214792774!GO:0006284;base-excision repair;0.00348278871828247!GO:0032508;DNA duplex unwinding;0.00351090343869775!GO:0032392;DNA geometric change;0.00351090343869775!GO:0048471;perinuclear region of cytoplasm;0.00359293425097933!GO:0016023;cytoplasmic membrane-bound vesicle;0.00367766975838883!GO:0043414;biopolymer methylation;0.00380277904200743!GO:0004177;aminopeptidase activity;0.00384284107019536!GO:0051920;peroxiredoxin activity;0.00388086119937603!GO:0031124;mRNA 3'-end processing;0.00388086119937603!GO:0030118;clathrin coat;0.00388582734173106!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00391597005020005!GO:0009165;nucleotide biosynthetic process;0.00391685102778842!GO:0042770;DNA damage response, signal transduction;0.00410016727072274!GO:0003714;transcription corepressor activity;0.00414628332241208!GO:0016859;cis-trans isomerase activity;0.00417938706098686!GO:0008022;protein C-terminus binding;0.00453940435335693!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00465379221730758!GO:0045454;cell redox homeostasis;0.00471264033122908!GO:0022890;inorganic cation transmembrane transporter activity;0.00477610674116232!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00483683893396335!GO:0043596;nuclear replication fork;0.00492244443358105!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00494800464869143!GO:0044452;nucleolar part;0.00504599022370064!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00509851696422191!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00509851696422191!GO:0000910;cytokinesis;0.00534954539876438!GO:0019783;small conjugating protein-specific protease activity;0.00542824011333196!GO:0031252;leading edge;0.0056133932481885!GO:0009889;regulation of biosynthetic process;0.00573988118802914!GO:0048468;cell development;0.00573988118802914!GO:0008033;tRNA processing;0.00580165427641288!GO:0004843;ubiquitin-specific protease activity;0.00602260783813208!GO:0006268;DNA unwinding during replication;0.00602260783813208!GO:0046822;regulation of nucleocytoplasmic transport;0.00612664704801297!GO:0004003;ATP-dependent DNA helicase activity;0.00631856344844108!GO:0051090;regulation of transcription factor activity;0.00653375287858529!GO:0008624;induction of apoptosis by extracellular signals;0.00656159273791444!GO:0009124;nucleoside monophosphate biosynthetic process;0.00659132159095165!GO:0009123;nucleoside monophosphate metabolic process;0.00659132159095165!GO:0000049;tRNA binding;0.00667658164506763!GO:0042393;histone binding;0.00671001759968542!GO:0043488;regulation of mRNA stability;0.00671001759968542!GO:0043487;regulation of RNA stability;0.00671001759968542!GO:0030518;steroid hormone receptor signaling pathway;0.00699334250739557!GO:0051251;positive regulation of lymphocyte activation;0.00700682603530367!GO:0016788;hydrolase activity, acting on ester bonds;0.00704672478924601!GO:0048487;beta-tubulin binding;0.00724314272398309!GO:0051789;response to protein stimulus;0.00732073485020031!GO:0006986;response to unfolded protein;0.00732073485020031!GO:0031123;RNA 3'-end processing;0.0073849922424257!GO:0030127;COPII vesicle coat;0.00741145636512671!GO:0012507;ER to Golgi transport vesicle membrane;0.00741145636512671!GO:0032200;telomere organization and biogenesis;0.00755400545025216!GO:0000723;telomere maintenance;0.00755400545025216!GO:0016584;nucleosome positioning;0.0076216224906103!GO:0030521;androgen receptor signaling pathway;0.00771204567263251!GO:0043621;protein self-association;0.00780995606088704!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00800759133301236!GO:0030663;COPI coated vesicle membrane;0.00810794762738398!GO:0030126;COPI vesicle coat;0.00810794762738398!GO:0016301;kinase activity;0.00828666414302383!GO:0030695;GTPase regulator activity;0.0085074814280325!GO:0046966;thyroid hormone receptor binding;0.0085074814280325!GO:0003746;translation elongation factor activity;0.00852385002818734!GO:0030134;ER to Golgi transport vesicle;0.00852385002818734!GO:0016605;PML body;0.00857329495144263!GO:0004221;ubiquitin thiolesterase activity;0.00872190696908789!GO:0051223;regulation of protein transport;0.00884990983210855!GO:0008047;enzyme activator activity;0.00889994843795223!GO:0006950;response to stress;0.00937098135308428!GO:0004722;protein serine/threonine phosphatase activity;0.00964188711109185!GO:0046914;transition metal ion binding;0.00989084164037699!GO:0000819;sister chromatid segregation;0.00991723016437215!GO:0030137;COPI-coated vesicle;0.00996116027773712!GO:0005774;vacuolar membrane;0.0103647101818947!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0105849717238597!GO:0043281;regulation of caspase activity;0.0106879286634046!GO:0005521;lamin binding;0.0106879286634046!GO:0035258;steroid hormone receptor binding;0.0107376187205908!GO:0000339;RNA cap binding;0.0107676266318048!GO:0009112;nucleobase metabolic process;0.0109066873985106!GO:0008637;apoptotic mitochondrial changes;0.0109120479359136!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0109733328568916!GO:0044438;microbody part;0.0110652852379521!GO:0044439;peroxisomal part;0.0110652852379521!GO:0016311;dephosphorylation;0.0110689768677811!GO:0042158;lipoprotein biosynthetic process;0.0112273259539111!GO:0051336;regulation of hydrolase activity;0.0112756396221252!GO:0005876;spindle microtubule;0.0114135161399123!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0114135161399123!GO:0031902;late endosome membrane;0.0114375324221536!GO:0006007;glucose catabolic process;0.0118287409329213!GO:0006355;regulation of transcription, DNA-dependent;0.0119163959079447!GO:0009116;nucleoside metabolic process;0.0121431913206174!GO:0004532;exoribonuclease activity;0.0121825797798503!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0121825797798503!GO:0006626;protein targeting to mitochondrion;0.0122523694356705!GO:0006506;GPI anchor biosynthetic process;0.012424633826303!GO:0042101;T cell receptor complex;0.0126065519958268!GO:0006376;mRNA splice site selection;0.0126065519958268!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0126065519958268!GO:0006505;GPI anchor metabolic process;0.0126330959603022!GO:0030880;RNA polymerase complex;0.0127033866485127!GO:0000070;mitotic sister chromatid segregation;0.0127688389950438!GO:0016272;prefoldin complex;0.0128056640763881!GO:0006839;mitochondrial transport;0.0131047128011995!GO:0008139;nuclear localization sequence binding;0.0131725897233395!GO:0005874;microtubule;0.0131960459486399!GO:0008287;protein serine/threonine phosphatase complex;0.0132034819856635!GO:0032940;secretion by cell;0.0133400910513311!GO:0009161;ribonucleoside monophosphate metabolic process;0.0136244535885645!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0136244535885645!GO:0016790;thiolester hydrolase activity;0.0136244535885645!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.0138471900360947!GO:0045045;secretory pathway;0.0140323759186731!GO:0044454;nuclear chromosome part;0.0140782235625183!GO:0019901;protein kinase binding;0.014086018766609!GO:0000059;protein import into nucleus, docking;0.0141269146700318!GO:0006144;purine base metabolic process;0.0145810092593207!GO:0004197;cysteine-type endopeptidase activity;0.0145821402604984!GO:0016791;phosphoric monoester hydrolase activity;0.0146352044787592!GO:0031570;DNA integrity checkpoint;0.0147669645276166!GO:0005669;transcription factor TFIID complex;0.0147887251725278!GO:0000781;chromosome, telomeric region;0.0147974077594883!GO:0005070;SH3/SH2 adaptor activity;0.0148337365330116!GO:0000792;heterochromatin;0.0149364770020191!GO:0008408;3'-5' exonuclease activity;0.015139322326109!GO:0030867;rough endoplasmic reticulum membrane;0.0151435018521028!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0151545790343311!GO:0031903;microbody membrane;0.0153013187660722!GO:0005778;peroxisomal membrane;0.0153013187660722!GO:0019079;viral genome replication;0.0153129778805138!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0154890114116431!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0156538288858333!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0160444352423475!GO:0030522;intracellular receptor-mediated signaling pathway;0.0163644567224994!GO:0005788;endoplasmic reticulum lumen;0.016549235770777!GO:0046649;lymphocyte activation;0.0168286341293277!GO:0008017;microtubule binding;0.0168336674284918!GO:0043601;nuclear replisome;0.01694216540454!GO:0030894;replisome;0.01694216540454!GO:0051249;regulation of lymphocyte activation;0.01694216540454!GO:0033116;ER-Golgi intermediate compartment membrane;0.01694216540454!GO:0050865;regulation of cell activation;0.0171889140667906!GO:0040029;regulation of gene expression, epigenetic;0.0172408091445793!GO:0005765;lysosomal membrane;0.0175314634900297!GO:0005869;dynactin complex;0.0176031988104223!GO:0000152;nuclear ubiquitin ligase complex;0.0177031760965557!GO:0051539;4 iron, 4 sulfur cluster binding;0.017900574441906!GO:0051881;regulation of mitochondrial membrane potential;0.018328546636741!GO:0006378;mRNA polyadenylation;0.0183617582340008!GO:0030125;clathrin vesicle coat;0.0184385441238569!GO:0030665;clathrin coated vesicle membrane;0.0184385441238569!GO:0044450;microtubule organizing center part;0.0185773285135285!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0186619511890404!GO:0015002;heme-copper terminal oxidase activity;0.0186619511890404!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0186619511890404!GO:0004129;cytochrome-c oxidase activity;0.0186619511890404!GO:0019900;kinase binding;0.0186986748256079!GO:0007034;vacuolar transport;0.0187146288256009!GO:0000725;recombinational repair;0.018720714834126!GO:0000724;double-strand break repair via homologous recombination;0.018720714834126!GO:0018193;peptidyl-amino acid modification;0.0194378564188354!GO:0022406;membrane docking;0.0194384512385537!GO:0048278;vesicle docking;0.0194384512385537!GO:0000738;DNA catabolic process, exonucleolytic;0.0197108995817458!GO:0008276;protein methyltransferase activity;0.0197764867948677!GO:0046467;membrane lipid biosynthetic process;0.0200410446501071!GO:0005083;small GTPase regulator activity;0.020414141901262!GO:0000018;regulation of DNA recombination;0.020428943866851!GO:0051338;regulation of transferase activity;0.0208494923700243!GO:0044437;vacuolar part;0.0209359844768838!GO:0006914;autophagy;0.0211003134574692!GO:0019210;kinase inhibitor activity;0.0211117959447896!GO:0004576;oligosaccharyl transferase activity;0.0212919616116265!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0212919616116265!GO:0015980;energy derivation by oxidation of organic compounds;0.0213305020864226!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0215273957078881!GO:0000428;DNA-directed RNA polymerase complex;0.0215273957078881!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0216128673540181!GO:0043022;ribosome binding;0.0217113230637002!GO:0005832;chaperonin-containing T-complex;0.0221841299449928!GO:0051053;negative regulation of DNA metabolic process;0.0224875664232369!GO:0016569;covalent chromatin modification;0.0226131561575641!GO:0032981;mitochondrial respiratory chain complex I assembly;0.022781752016602!GO:0010257;NADH dehydrogenase complex assembly;0.022781752016602!GO:0033108;mitochondrial respiratory chain complex assembly;0.022781752016602!GO:0016763;transferase activity, transferring pentosyl groups;0.0231385917789741!GO:0045936;negative regulation of phosphate metabolic process;0.0233416362872436!GO:0009966;regulation of signal transduction;0.0236747162767365!GO:0051235;maintenance of localization;0.0237681974083446!GO:0006275;regulation of DNA replication;0.023857164983269!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0239637779676139!GO:0006904;vesicle docking during exocytosis;0.0240057701208318!GO:0007259;JAK-STAT cascade;0.0242291349465102!GO:0019058;viral infectious cycle;0.0244299058435738!GO:0031625;ubiquitin protein ligase binding;0.0245516381861603!GO:0006091;generation of precursor metabolites and energy;0.0248504821907055!GO:0004721;phosphoprotein phosphatase activity;0.0248504821907055!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0248504821907055!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0248504821907055!GO:0009126;purine nucleoside monophosphate metabolic process;0.0248504821907055!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0248504821907055!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0248504821907055!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0248504821907055!GO:0051098;regulation of binding;0.0249841113273495!GO:0000726;non-recombinational repair;0.0253055978445456!GO:0008250;oligosaccharyl transferase complex;0.0254072543215691!GO:0006595;polyamine metabolic process;0.0254424978643338!GO:0004860;protein kinase inhibitor activity;0.0254424978643338!GO:0048524;positive regulation of viral reproduction;0.0256534387847912!GO:0016860;intramolecular oxidoreductase activity;0.0257700646386666!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0263096463220935!GO:0046365;monosaccharide catabolic process;0.0264821105968092!GO:0008629;induction of apoptosis by intracellular signals;0.026657278987906!GO:0042608;T cell receptor binding;0.0270058519684134!GO:0008097;5S rRNA binding;0.0274691739913249!GO:0030119;AP-type membrane coat adaptor complex;0.028146670899012!GO:0003725;double-stranded RNA binding;0.0281577341065557!GO:0030133;transport vesicle;0.0285740830950809!GO:0046982;protein heterodimerization activity;0.0286990582540701!GO:0017134;fibroblast growth factor binding;0.0293862873473804!GO:0019904;protein domain specific binding;0.0296008134214793!GO:0006919;caspase activation;0.0296553156210596!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0296553156210596!GO:0033673;negative regulation of kinase activity;0.0296553156210596!GO:0006469;negative regulation of protein kinase activity;0.0296553156210596!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0297245436355075!GO:0043549;regulation of kinase activity;0.0297245436355075!GO:0008320;protein transmembrane transporter activity;0.0298513367240488!GO:0000077;DNA damage checkpoint;0.0301160539683573!GO:0022411;cellular component disassembly;0.0311659223228787!GO:0030833;regulation of actin filament polymerization;0.0314462314817366!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0314462314817366!GO:0005665;DNA-directed RNA polymerase II, core complex;0.031833493260702!GO:0051540;metal cluster binding;0.031833493260702!GO:0051536;iron-sulfur cluster binding;0.031833493260702!GO:0050852;T cell receptor signaling pathway;0.0319767050097437!GO:0005784;translocon complex;0.0322892729750909!GO:0005791;rough endoplasmic reticulum;0.0323295460994392!GO:0005095;GTPase inhibitor activity;0.0323295460994392!GO:0006270;DNA replication initiation;0.0325924646151957!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0328757767213709!GO:0008213;protein amino acid alkylation;0.0330044386510031!GO:0006479;protein amino acid methylation;0.0330044386510031!GO:0004659;prenyltransferase activity;0.0333425954136614!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0333425954136614!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0333425954136614!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0333425954136614!GO:0046426;negative regulation of JAK-STAT cascade;0.0338771005735993!GO:0000793;condensed chromosome;0.0342896402559273!GO:0030131;clathrin adaptor complex;0.0343014756905977!GO:0030176;integral to endoplasmic reticulum membrane;0.0345470673066403!GO:0000178;exosome (RNase complex);0.0346183722130779!GO:0031577;spindle checkpoint;0.0346369020938584!GO:0046164;alcohol catabolic process;0.0347042047916112!GO:0051348;negative regulation of transferase activity;0.0347124823569517!GO:0030132;clathrin coat of coated pit;0.0347733152328724!GO:0003887;DNA-directed DNA polymerase activity;0.0350690873001232!GO:0006266;DNA ligation;0.0351379626130876!GO:0046483;heterocycle metabolic process;0.0352522834104139!GO:0022884;macromolecule transmembrane transporter activity;0.0356752317268121!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0356752317268121!GO:0045792;negative regulation of cell size;0.036112771403669!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0361374859858299!GO:0045892;negative regulation of transcription, DNA-dependent;0.0361623495602573!GO:0050681;androgen receptor binding;0.0371761711184886!GO:0050870;positive regulation of T cell activation;0.0374094737261004!GO:0008538;proteasome activator activity;0.0374268547910616!GO:0008180;signalosome;0.0382303769325608!GO:0051452;cellular pH reduction;0.0382534992546908!GO:0051453;regulation of cellular pH;0.0382534992546908!GO:0045851;pH reduction;0.0382534992546908!GO:0030041;actin filament polymerization;0.0388827769553524!GO:0005092;GDP-dissociation inhibitor activity;0.0388929652328172!GO:0050811;GABA receptor binding;0.0393852323230308!GO:0005096;GTPase activator activity;0.0405270555693131!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0405582410170796!GO:0019320;hexose catabolic process;0.0407530653801699!GO:0007021;tubulin folding;0.0410475381833448!GO:0002378;immunoglobulin biosynthetic process;0.0411553936454933!GO:0001911;negative regulation of leukocyte mediated cytotoxicity;0.0411553936454933!GO:0001915;negative regulation of T cell mediated cytotoxicity;0.0411553936454933!GO:0006406;mRNA export from nucleus;0.0416478883454848!GO:0016570;histone modification;0.0421743150806551!GO:0005777;peroxisome;0.0422736777229644!GO:0042579;microbody;0.0422736777229644!GO:0030258;lipid modification;0.0423301039305599!GO:0000123;histone acetyltransferase complex;0.0428099189801253!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0429711488697483!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0429711488697483!GO:0046979;TAP2 binding;0.0433423815562458!GO:0046977;TAP binding;0.0433423815562458!GO:0046978;TAP1 binding;0.0433423815562458!GO:0050863;regulation of T cell activation;0.0436671954547347!GO:0030308;negative regulation of cell growth;0.0436671954547347!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0446251466616942!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0446251466616942!GO:0051059;NF-kappaB binding;0.0446619459287054!GO:0006516;glycoprotein catabolic process;0.0447861342780708!GO:0001836;release of cytochrome c from mitochondria;0.0453263051180246!GO:0042326;negative regulation of phosphorylation;0.0453346013654336!GO:0051091;positive regulation of transcription factor activity;0.0454432001605753!GO:0030332;cyclin binding;0.0465915282026773!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0468014807537974!GO:0031371;ubiquitin conjugating enzyme complex;0.0470022734761387!GO:0019976;interleukin-2 binding;0.0473272847614655!GO:0004911;interleukin-2 receptor activity;0.0473272847614655!GO:0045815;positive regulation of gene expression, epigenetic;0.0475660377719679!GO:0006470;protein amino acid dephosphorylation;0.0476348143716271!GO:0000096;sulfur amino acid metabolic process;0.0476348143716271!GO:0007017;microtubule-based process;0.0476348143716271!GO:0045859;regulation of protein kinase activity;0.0476348143716271!GO:0019318;hexose metabolic process;0.0478778981595671!GO:0046983;protein dimerization activity;0.0478778981595671!GO:0005996;monosaccharide metabolic process;0.0480590537221135!GO:0043284;biopolymer biosynthetic process;0.048124673121809!GO:0003950;NAD+ ADP-ribosyltransferase activity;0.048581529988135!GO:0008625;induction of apoptosis via death domain receptors;0.0485936565088789!GO:0006984;ER-nuclear signaling pathway;0.0491418227826723!GO:0043631;RNA polyadenylation;0.0493383290444089!GO:0006096;glycolysis;0.0498124958843946!GO:0015923;mannosidase activity;0.0498124958843946 | |||
|sample_id=11792 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=ELF1,2,4:2.4225797992;CDX1,2,4:2.36152109406;PAX3,7:2.02955706361;TLX2:1.97495991439;RUNX1..3:1.80823656688;RORA:1.71028300915;PAX4:1.44400919428;ETS1,2:1.38177498649;POU1F1:1.32997559008;PDX1:1.26214604126;SPI1:1.2572236128;STAT1,3:1.25025715905;GATA6:1.24581861593;E2F1..5:1.24316591859;ZBTB16:1.14427908245;DMAP1_NCOR{1,2}_SMARC:1.13162252043;IKZF2:0.995564317624;ELK1,4_GABP{A,B1}:0.99351125788;IRF1,2:0.934219235629;T:0.919102345962;SPIB:0.891876347594;YY1:0.870388825265;PBX1:0.810769520764;NFY{A,B,C}:0.77872957115;FOXA2:0.743621136257;PITX1..3:0.723150673655;FOX{F1,F2,J1}:0.718544149635;BREu{core}:0.716569585125;CRX:0.699200147735;POU2F1..3:0.622188965876;LEF1_TCF7_TCF7L1,2:0.616154337024;TGIF1:0.61105031882;FOXP1:0.593509608725;NKX6-1,2:0.592124060955;MYB:0.573887419428;NKX2-2,8:0.55223844389;PAX8:0.547027498561;NANOG{mouse}:0.453961723694;IRF7:0.434031238455;MYOD1:0.429398501394;FOXO1,3,4:0.407153723862;NKX3-1:0.398875009398;NRF1:0.341411297461;SNAI1..3:0.324741621181;FOXM1:0.319624909439;BPTF:0.306981226276;ZEB1:0.299655584488;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.275572082126;OCT4_SOX2{dimer}:0.265882398857;RFX2..5_RFXANK_RFXAP:0.261777491931;ATF5_CREB3:0.246975281701;CREB1:0.243028612516;LMO2:0.218497393815;NR5A1,2:0.208572686042;STAT5{A,B}:0.183060426671;ZNF143:0.162951928202;SREBF1,2:0.156525542056;SPZ1:0.152270212342;FOX{D1,D2}:0.151274635406;AIRE:0.142274490519;CUX2:0.124698292138;HMX1:0.118238225192;HOX{A6,A7,B6,B7}:0.0982188030934;POU3F1..4:0.0978713199498;STAT2,4,6:0.0735893297243;FOX{I1,J2}:0.065328192823;SOX5:0.0312451627311;ALX1:0.00495541391476;FOXN1:-0.0230689976995;NFKB1_REL_RELA:-0.0409055225295;GFI1:-0.0560383240444;NR3C1:-0.0736799319077;PAX2:-0.0903577577763;GCM1,2:-0.0910314572599;HES1:-0.0933115389313;NKX2-1,4:-0.117062127864;JUN:-0.119819618523;AHR_ARNT_ARNT2:-0.141000178831;TFDP1:-0.155468566125;EP300:-0.160507880565;PAX6:-0.164526037412;HNF4A_NR2F1,2:-0.181668219889;TOPORS:-0.194332227294;PRRX1,2:-0.212845912842;NFATC1..3:-0.227735659826;TAL1_TCF{3,4,12}:-0.23318023217;NFIL3:-0.236948116103;FOXD3:-0.245243066725;RXRA_VDR{dimer}:-0.26017118765;SMAD1..7,9:-0.272122435622;GLI1..3:-0.274660697923;AR:-0.288301781438;ZNF148:-0.296491567897;NFE2L1:-0.309885736413;ATF4:-0.318511990286;HNF1A:-0.349609679472;NR1H4:-0.379115776318;RREB1:-0.388351379183;EVI1:-0.389934137742;HAND1,2:-0.415326012888;ZNF423:-0.426949778269;POU5F1:-0.428440522956;MYFfamily:-0.431128257173;SOX2:-0.433534868007;FOXQ1:-0.438131373726;HMGA1,2:-0.439580113102;ARID5B:-0.440268658138;VSX1,2:-0.464111085295;SOX{8,9,10}:-0.475945155446;ATF2:-0.478694303029;HOXA9_MEIS1:-0.486701938644;ADNP_IRX_SIX_ZHX:-0.489684832136;NKX2-3_NKX2-5:-0.510251975502;ZNF384:-0.524965854372;FOXP3:-0.526428299005;RBPJ:-0.548466043177;PPARG:-0.553919853902;ATF6:-0.566257832951;RFX1:-0.566496712603;BACH2:-0.570455727829;ZNF238:-0.571437266393;SRF:-0.574481660626;NFIX:-0.576535207054;NFE2L2:-0.581957109905;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.589400106455;CEBPA,B_DDIT3:-0.593482304493;FOS_FOS{B,L1}_JUN{B,D}:-0.604473419897;TFCP2:-0.621479883174;NFE2:-0.628712506912;TFAP4:-0.63240555448;ESR1:-0.64814802849;FOSL2:-0.696267014346;HLF:-0.711557056722;NHLH1,2:-0.712677301859;TP53:-0.737054020332;HBP1_HMGB_SSRP1_UBTF:-0.75193336092;NANOG:-0.754396555554;PAX5:-0.784863457083;UFEwm:-0.792441220222;REST:-0.794309858934;ALX4:-0.802971727954;ESRRA:-0.807918499612;DBP:-0.815819468543;ONECUT1,2:-0.827904147989;XCPE1{core}:-0.883599924917;LHX3,4:-0.889661510277;MEF2{A,B,C,D}:-0.896761673748;ZBTB6:-0.90936508934;CDC5L:-0.934340491975;MED-1{core}:-0.939824504668;HOX{A5,B5}:-0.973799782254;MZF1:-0.974574666273;MYBL2:-0.984708508093;TBX4,5:-1.03093035664;GFI1B:-1.04419037794;SOX17:-1.05084037165;MTE{core}:-1.08458474303;ZFP161:-1.11059656206;NR6A1:-1.11110666689;GATA4:-1.11312469188;KLF4:-1.11418270695;MAFB:-1.12147562741;HIF1A:-1.13885659483;EBF1:-1.14250238556;MAZ:-1.1593502465;PRDM1:-1.1900718137;GTF2I:-1.21018412467;HOX{A4,D4}:-1.22547153947;HSF1,2:-1.24396222762;EGR1..3:-1.26478206479;MTF1:-1.2657690984;POU6F1:-1.27340077154;TEF:-1.31277077181;GZF1:-1.32634814926;NKX3-2:-1.32664433237;EN1,2:-1.38652391648;GTF2A1,2:-1.39009122427;TFAP2B:-1.43396329261;bHLH_family:-1.44501274323;PATZ1:-1.44676798902;HIC1:-1.45503082563;TBP:-1.46404935128;ZIC1..3:-1.47356279401;RXR{A,B,G}:-1.58045686094;TFAP2{A,C}:-1.58151443374;TEAD1:-1.58979762693;SP1:-1.64935541454;TLX1..3_NFIC{dimer}:-1.7761799137;XBP1:-1.79941677996;PAX1,9:-1.80675293102;IKZF1:-1.98534804817;FOXL1:-2.03566617497 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11792-124C1;search_select_hide=table117:FF:11792-124C1 | |||
}} | }} |
Latest revision as of 18:20, 4 June 2020
Name: | CD4+CD25-CD45RA- memory conventional T cells expanded, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13215 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13215
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13215
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.113 |
10 | 10 | 0.0103 |
100 | 100 | 0.767 |
101 | 101 | 0.0955 |
102 | 102 | 0.522 |
103 | 103 | 0.16 |
104 | 104 | 0.679 |
105 | 105 | 0.154 |
106 | 106 | 0.596 |
107 | 107 | 0.478 |
108 | 108 | 0.675 |
109 | 109 | 0.0406 |
11 | 11 | 0.0402 |
110 | 110 | 0.411 |
111 | 111 | 0.384 |
112 | 112 | 0.122 |
113 | 113 | 0.474 |
114 | 114 | 0.238 |
115 | 115 | 0.116 |
116 | 116 | 0.582 |
117 | 117 | 0.0064 |
118 | 118 | 0.4 |
119 | 119 | 0.539 |
12 | 12 | 0.509 |
120 | 120 | 0.482 |
121 | 121 | 0.634 |
122 | 122 | 0.326 |
123 | 123 | 4.42326e-4 |
124 | 124 | 0.0599 |
125 | 125 | 0.978 |
126 | 126 | 0.434 |
127 | 127 | 0.377 |
128 | 128 | 0.663 |
129 | 129 | 0.161 |
13 | 13 | 0.415 |
130 | 130 | 0.889 |
131 | 131 | 0.803 |
132 | 132 | 0.959 |
133 | 133 | 0.247 |
134 | 134 | 0.702 |
135 | 135 | 0.748 |
136 | 136 | 0.657 |
137 | 137 | 0.0709 |
138 | 138 | 0.289 |
139 | 139 | 0.268 |
14 | 14 | 0.396 |
140 | 140 | 0.0213 |
141 | 141 | 0.655 |
142 | 142 | 0.952 |
143 | 143 | 0.00139 |
144 | 144 | 0.479 |
145 | 145 | 0.248 |
146 | 146 | 0.442 |
147 | 147 | 0.0258 |
148 | 148 | 0.0669 |
149 | 149 | 0.807 |
15 | 15 | 0.0998 |
150 | 150 | 0.463 |
151 | 151 | 0.6 |
152 | 152 | 0.329 |
153 | 153 | 0.982 |
154 | 154 | 0.724 |
155 | 155 | 0.0143 |
156 | 156 | 0.585 |
157 | 157 | 0.0644 |
158 | 158 | 0.289 |
159 | 159 | 0.383 |
16 | 16 | 0.623 |
160 | 160 | 0.559 |
161 | 161 | 0.175 |
162 | 162 | 0.166 |
163 | 163 | 0.448 |
164 | 164 | 0.118 |
165 | 165 | 0.183 |
166 | 166 | 0.797 |
167 | 167 | 0.269 |
168 | 168 | 0.2 |
169 | 169 | 0.348 |
17 | 17 | 0.872 |
18 | 18 | 0.611 |
19 | 19 | 0.609 |
2 | 2 | 0.909 |
20 | 20 | 0.758 |
21 | 21 | 0.312 |
22 | 22 | 0.989 |
23 | 23 | 0.54 |
24 | 24 | 0.586 |
25 | 25 | 0.0645 |
26 | 26 | 0.123 |
27 | 27 | 0.155 |
28 | 28 | 0.56 |
29 | 29 | 0.0176 |
3 | 3 | 0.0464 |
30 | 30 | 0.198 |
31 | 31 | 0.932 |
32 | 32 | 0.307 |
33 | 33 | 0.528 |
34 | 34 | 0.958 |
35 | 35 | 0.185 |
36 | 36 | 0.0248 |
37 | 37 | 0.229 |
38 | 38 | 0.666 |
39 | 39 | 0.318 |
4 | 4 | 0.609 |
40 | 40 | 0.348 |
41 | 41 | 0.485 |
42 | 42 | 0.0647 |
43 | 43 | 0.444 |
44 | 44 | 0.268 |
45 | 45 | 0.499 |
46 | 46 | 0.0895 |
47 | 47 | 0.0115 |
48 | 48 | 0.0349 |
49 | 49 | 0.161 |
5 | 5 | 0.565 |
50 | 50 | 0.786 |
51 | 51 | 0.609 |
52 | 52 | 0.298 |
53 | 53 | 0.216 |
54 | 54 | 0.806 |
55 | 55 | 0.552 |
56 | 56 | 0.465 |
57 | 57 | 0.206 |
58 | 58 | 0.111 |
59 | 59 | 0.31 |
6 | 6 | 0.673 |
60 | 60 | 0.514 |
61 | 61 | 0.0812 |
62 | 62 | 0.0481 |
63 | 63 | 0.514 |
64 | 64 | 0.128 |
65 | 65 | 0.916 |
66 | 66 | 0.819 |
67 | 67 | 0.924 |
68 | 68 | 0.688 |
69 | 69 | 0.864 |
7 | 7 | 0.243 |
70 | 70 | 0.0586 |
71 | 71 | 0.0351 |
72 | 72 | 0.0561 |
73 | 73 | 0.552 |
74 | 74 | 0.379 |
75 | 75 | 0.0162 |
76 | 76 | 0.434 |
77 | 77 | 0.754 |
78 | 78 | 0.0296 |
79 | 79 | 0.239 |
8 | 8 | 0.431 |
80 | 80 | 0.0948 |
81 | 81 | 0.42 |
82 | 82 | 0.139 |
83 | 83 | 0.614 |
84 | 84 | 0.196 |
85 | 85 | 0.705 |
86 | 86 | 0.168 |
87 | 87 | 0.362 |
88 | 88 | 0.749 |
89 | 89 | 0.682 |
9 | 9 | 0.761 |
90 | 90 | 0.0166 |
91 | 91 | 0.636 |
92 | 92 | 0.395 |
93 | 93 | 0.205 |
94 | 94 | 0.107 |
95 | 95 | 0.0103 |
96 | 96 | 0.0541 |
97 | 97 | 0.311 |
98 | 98 | 0.303 |
99 | 99 | 0.247 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13215
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000002 in vivo cell sample
FF:0000210 human sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA