FF:10427-106D4: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005039 | ||
| | |accession_numbers=CAGE;DRX007831;DRR008703;DRZ000128;DRZ001513;DRZ011478;DRZ012863 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000945,CL:0000738,CL:0002087,CL:0002242,CL:0000255 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0101522 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr6:391743..391759,+!p1@IRF4!2.62!415.29!IRF4;;chr11:111249993..111250006,-!p1@POU2AF1!2.58!381.19!POU2AF1;;chr16:85932760..85932775,+!p1@IRF8!2.33!210.60!IRF8;;chr2:68592406..68592424,+!p1@PLEK!2.26!181.92!PLEK;;chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!2.25!175.89!MEF2B;;chr19:50922187..50922204,+!p1@SPIB!2.21!161.73!SPIB;;chr19:36204309..36204335,+!p1@ZBTB32!2.08!119.27!ZBTB32;;chr3:101546827..101546847,+!p2@NFKBIZ!1.89!105.24!NFKBIZ;;chr17:38020392..38020477,-!p1@IKZF3!1.88!74.59!IKZF3;;chr2:231090433..231090469,+!p1@SP140!1.82!64.87!SP140;;chr2:231090471..231090504,+!p2@SP140!1.77!58.47!SP140;;chr14:75988831..75988847,+!p2@BATF!1.76!56.00!BATF;;chr15:57511609..57511651,+!p2@TCF12!1.73!86.04!TCF12;;chr14:75988771..75988826,+!p1@BATF!1.73!68.68!BATF;;chr12:101869096..101869118,+!p1@SPIC!1.69!48.37!SPIC;;chr8:135577829..135577861,-!p6@ZFAT!1.59!38.16!ZFAT;;chr3:189349162..189349207,+!p2@TP63!1.56!35.08!TP63;;chr1:25256756..25256774,-!p1@RUNX3!1.51!58.22!RUNX3;;chr19:42636586..42636607,-!p1@POU2F2!1.48!79.51!POU2F2;;chr6:144385698..144385742,-!p2@PLAGL1!1.46!33.97!PLAGL1;;chr4:185395590..185395627,-!p3@IRF2!1.44!32.74!IRF2;;chr1:25291475..25291511,-!p2@RUNX3!1.43!26.22!RUNX3;;chr1:3569072..3569093,+!p1@TP73!1.42!25.23!TP73;;chr2:185463247..185463263,+!p1@ZNF804A!1.41!43.20!ZNF804A;;chr1:170632115..170632136,+!p9@PRRX1!1.38!22.89!PRRX1;;chr2:68592394..68592405,+!p2@PLEK!1.37!22.40!PLEK;;chr19:42627037..42627084,-!p3@POU2F2!1.34!21.05!POU2F2;;chrY:21906594..21906622,-!p1@KDM5D!1.34!21.05!KDM5D;;chr11:47400078..47400106,-!p1@SPI1!1.33!20.19!SPI1;;chr5:88178983..88179012,-!p1@MEF2C!1.28!135.02!MEF2C;;chr14:29235961..29236008,+!p1@FOXG1!1.28!18.22!FOXG1;;chr18:52989031..52989079,-!p2@TCF4!1.27!40.86!TCF4;;chr2:231090344..231090361,-!p3@SP110!1.25!16.74!SP110;;chr7:128577972..128578047,+!p1@IRF5!1.24!25.48!IRF5;;chr7:50348268..50348366,+!p4@IKZF1!1.24!16.49!IKZF1;;chr8:76319876..76319926,+!p1@HNF4G!1.24!16.49!HNF4G;;chr7:28610099..28610113,+!p5@CREB5!1.24!16.25!CREB5;;chr9:37034469..37034474,-!p1@PAX5!1.23!15.88!PAX5;;chr14:29236269..29236285,+!p3@FOXG1!1.22!15.63!FOXG1;;chr1:201979703..201979721,+!p2@ELF3!1.19!14.52!ELF3;;chr15:60884706..60884743,-!p1@RORA!1.17!71.02!RORA;;chr7:50343634..50343717,+!p2@IKZF1!1.17!13.91!IKZF1;;chr1:170632137..170632172,+!p10@PRRX1!1.17!13.79!PRRX1;;chr8:72756667..72756736,-!p2@MSC!1.16!20.80!MSC;;chr15:57511589..57511608,+!p4@TCF12!1.16!13.29!TCF12;;chr11:61520075..61520136,+!p1@C11orf9!1.15!28.06!C11orf9;;chr1:27023752..27023799,+!p4@ARID1A!1.15!17.23!ARID1A;;chr5:142780237..142780261,-!p7@NR3C1!1.15!13.05!NR3C1;;chr6:44233252..44233296,-!p1@NFKBIE!1.12!118.90!NFKBIE;;chr8:72756637..72756664,-!p3@MSC!1.12!13.79!MSC;;chr6:41700616..41700664,-!p8@TFEB!1.12!12.19!TFEB;;chr17:36105042..36105060,-!p1@HNF1B!1.12!12.06!HNF1B;;chr13:41593425..41593480,-!p1@ELF1!1.11!74.84!ELF1;;chr20:50159198..50159299,-!p1@NFATC2!1.10!16.86!NFATC2;;chr5:142782823..142782854,-!p3@NR3C1!1.08!15.88!NR3C1;;chr8:22550982..22550999,-!p1@EGR3!1.07!30.77!EGR3;;chr4:146859626..146859669,-!p2@ZNF827!1.07!15.63!ZNF827;;chr13:28494130..28494168,+!p1@PDX1!1.06!10.46!PDX1;;chr19:50432453..50432468,+!p1@ATF5!1.05!574.44!ATF5;;chr11:615570..615721,-!p2@IRF7!1.05!20.43!IRF7;;chr1:170632051..170632081,+!p16@PRRX1!1.05!10.34!PRRX1;;chr19:45252008..45252024,+!p2@BCL3!1.04!33.36!BCL3;;chr3:141121847..141121868,+!p5@ZBTB38!1.04!15.14!ZBTB38;;chr5:88179017..88179046,-!p2@MEF2C!1.03!39.88!MEF2C;;chr17:40440359..40440386,+!p4@STAT5A!1.03!9.72!STAT5A;;chr1:25291620..25291635,-!p4@RUNX3!1.03!9.60!RUNX3;;chr17:45810594..45810608,+!p1@TBX21!1.02!9.48!TBX21;;chr8:86099884..86099918,+!p4@E2F5!1.02!9.48!E2F5;;chr10:104155480..104155534,+!p2@NFKB2!1.01!61.05!NFKB2;;chr6:106534192..106534224,+!p1@PRDM1!1.01!26.71!PRDM1;;chr8:72756063..72756125,-!p1@MSC!1.01!18.83!MSC;;chr19:36391434..36391450,-!p1@NFKBID!1.01!18.22!NFKBID;;chr1:25291648..25291665,-!p7@RUNX3!1.00!9.11!RUNX3;;chr1:151319654..151319698,-!p2@RFX5!0.99!19.32!RFX5;;chr1:38512457..38512474,-!p1@POU3F1!0.99!9.72!POU3F1;;chr5:142780189..142780223,-!p6@NR3C1!0.99!8.86!NR3C1;;chr5:142780280..142780294,-!p16@NR3C1!0.99!8.74!NR3C1;;chr5:158526917..158526932,-!p1@EBF1!0.98!21.91!EBF1;;chr4:185395633..185395651,-!p2@IRF2!0.98!13.79!IRF2;;chr14:75988851..75988862,+!p3@BATF!0.98!8.62!BATF;;chr1:158979686..158979745,+!p1@IFI16!0.97!279.40!IFI16;;chr6:34204973..34204990,+!p4@HMGA1!0.97!115.08!HMGA1;;chr19:926001..926046,+!p1@ARID3A!0.97!29.42!ARID3A;;chr1:201979743..201979762,+!p1@ELF3!0.97!8.37!ELF3;;chr7:50344289..50344323,+!p1@IKZF1!0.97!8.37!IKZF1;;chr4:106068026..106068084,+!p1@TET2!0.96!76.07!TET2;;chr15:74833584..74833626,+!p1@ARID3B!0.96!19.45!ARID3B;;chr8:135577784..135577795,-!p15@ZFAT!0.96!8.12!ZFAT;;chr3:141747459..141747475,-!p1@TFDP2!0.95!67.57!TFDP2;;chr8:135577814..135577826,-!p12@ZFAT!0.95!7.88!ZFAT;;chr7:97840743..97840786,+!p1@BHLHA15!0.94!7.75!BHLHA15;;chr8:76319850..76319870,+!p4@HNF4G!0.94!7.75!HNF4G;;chr1:167298300..16729831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| |||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
|fonse_cell_line=FF:0101522 | |fonse_cell_line=FF:0101522 | ||
|fonse_cell_line_closure=FF:0101522 | |fonse_cell_line_closure=FF:0101522 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/b%2520cell%2520line%253aRPMI1788.CNhs10744.10427-106D4.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/b%2520cell%2520line%253aRPMI1788.CNhs10744.10427-106D4.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/b%2520cell%2520line%253aRPMI1788.CNhs10744.10427-106D4.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/b%2520cell%2520line%253aRPMI1788.CNhs10744.10427-106D4.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/b%2520cell%2520line%253aRPMI1788.CNhs10744.10427-106D4.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10427-106D4 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101522 | |||
|is_obsolete= | |||
|library_id=CNhs10744 | |||
|library_id_phase_based=2:CNhs10744 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10427 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10427 | |||
|name=b cell line:RPMI1788 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs10744,LSID692,release008,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.163503797819303,0.136484150373336,-0.27483329820609,-0.257197284782284,0,0,0,0,0,0,0,0,0,0,0.798833344515004,0,0,-0.102910458759113,0,0,0,0.377067961761502,0.371794071542173,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0,0.086933776658817,0,0,0,0,0,-0.188604515995527,0,0,0,0,0,0,0,0,0.0799282479631275,0,0,0,0.0955771563476108,0,-0.030342522150835,0.0504125515893149,-0.0465798096532902,0,0,0.20034652547592,0,0,0,0,0,0,0,0,0,0,0.47266239864144,0,0,0,0,0,0,0,0.086933776658817,0,0,0,0,0,-0.193767368279083,0.298520272804748,0,0,-0.0625741757750558,0.106235645450824,0,0,0.104143269075961,0,0.171849534894309,-0.0906886226270896,0,0,0,0.0955771563476108,0,0.12008845076301,0,0,0,0,0,0,0,0,0,0,0.136484150373336,0.657152421663515,0.0955771563476108,0,0,-0.126413687781747,-0.210124310365075,0,0,0,0,0,0 | |||
|repeat_enrich_byname=0,0,0.0504125515893149,0.523565859468153,0.171849534894309,0,0,0.173867553317634,0,0.454276412974832,0.597040545609496,0,0,0,0,0,-0.247178875285564,0.0252062757946575,-0.337602068378672,0.0303524107941623,0,0,-0.0455488593825915,0,0,0,0.0218411028522996,0.0955771563476108,0,0,0.0955771563476108,0,-0.128119866952565,0,0,0.0252062757946575,0.0955771563476108,0,0,-0.0186252810838506,0.129605278357179,0.0955771563476108,-0.106015985962841,-0.0179317094880533,0,0.0955771563476108,0,0,-0.115064817488839,0,0.294110980219486,-0.0827201683234173,0,-0.685993187181659,0.118155056536452,0,0,0,-0.531251475379497,-0.324765056222403,0,0,-0.121779851751874,0.00454741721042748,0.0252062757946575,0,-0.391044581551635,0,-0.0394003083043899,-0.128637272852421,0,0.144818828263238,0,0.0504125515893149,0,0,0,0.136484150373336,0,0,0.0504125515893149,0,0,-0.0574934668214365,0.0214813943617634,0.0252062757946575,0,0,0,0.0485715312401098,0,0,-0.00149208441439391,0.0541898514208278,0.0137763584868159,0.153337968088124,0,0.432494313679601,-0.00468790250729201,-0.507913548192155,-0.0625741757750558,-0.147401849371139,-0.189981719549847,0,-0.193767368279083,-0.786272629114012,0.0559789669553795,0.143932051168689,-0.0559559821752498,-1.2314085082871,-0.0777153136767694,0,0,0,-0.274842267365489,0,0,-0.394537558129163,-0.075357497301132,-0.347722460496175,-0.582980711059675,-0.281583747334341,-0.122322485306777,0.824924904783292,-0.283568899578961,-0.0414602028801487,-0.4215723249037,-0.125418664907255,0,-0.101054205936228,-0.0973979088635089,-0.15009776412483,0.191420003100782,0,0.331521671150663,-0.0683442610773682,0,-0.462410563617563,0.0126115561338194,0,-0.192351846826514,0.103875787495465,0,0,0.101737848892683,0,0,0.0212976727382688,0.465184931503463,0.00732133997047393,0,-0.00344737185058075,-0.15682751127339,0.221614270726648,0,0.150024992411393,-0.146009897457394,0.0651888217786282,-0.1561496542229,0,0.123978382164056,-0.0996213233386168,0.0634723375911503,0.116894134554038,-0.0584468268118252,0.138783840741601,-0.0725663087678337,0.243327585312459,-0.788939864790226,0.103102304202966,-0.0377142808859728,-0.210162025788965,-0.833132198929065,-0.583920975273914,-0.0359478440383096,-0.259526882266884,0,-0.743871426544291,0,0.097937449360802,0,0.206419233528613,-0.366566198155606,1.06105849484308,0.352039696235937,0,-0.371927279450616,0.841305821682896,0,-0.200614833559869,0,0,-0.150367083334639,-0.647283414923268,0.937158615697905,-0.0912008785053892,0,-0.790080158389657,0,0,-0.22567964651944,0.112993953276344,0,0.0726941564491708,-0.0121623686038997,-0.0350920433540794,-0.0203939170873233,0.0504125515893149,0,-0.645700337992725,0,0,-0.469443913444694,-0.176490564987516,-0.483299173585297,1.05468956419905,-0.0051059159752037,-0.108622809454255,0,0.173867553317634,0.0307587721867477,0.240176901526019,-0.108157158780416,0,0,0.004257814358931,0,0,0,0.0955771563476108,0,0,-0.00675790736601312,0,0,0.0252062757946575,0,0,-0.319030903011012,0.293172713708928,0,-0.0938209767449004,0,0,0,0,0,0,0,0.0504125515893149,0.0383588465226772,-0.0292311728675817,0.085269122475503,0.0252062757946575,0.0252062757946575,0.0934483509813255,0,-0.120146246205864,0.036940339431295,0.0504125515893149,0.138022179634384,0,0.0477885781738054,0,0,0.0503431605841249,0,0,0,0,0.0787536933196723,-0.126358419656866,0,0,0,-0.27695440160179,0,0,0,0,0.0658992695648464,0,0,-0.216939709373153,0,0.0882930525019334,-0.0311693279575265,0,0.0845961582158965,-0.141261504365534,-0.0458669557382561,0,0,-0.124862981416551,0,0.0252062757946575,0.126600030437514,-0.00624263383218276,0.0955771563476108,0,0,0,0,0,0,0.208286538151923,0.445550306583484,0,0,0,0,0,0.0504125515893149,0,0,0,0,0,-0.320393800656696,-0.0418115050691955,0,0,0,0,0,0,0,-0.0241060230789031,0.0620789256459889,0,0,0,0,0,0,0,0,0.125614605946254,0,0,0,0,0,-0.0465798096532902,0,0.323821827905689,0,0,-0.514394569564569,0,0,-0.226949580604199,0,0,0,0,0,0,0.0504125515893149,0,0,0,0.0504125515893149,0,0,0.0505484672821864,-0.392403931382539,0,0.136484150373336,0,0,0,0.136484150373336,0,-0.27483329820609,0,0,0.0955771563476108,0,0.059983179608657,0,0,0,-0.104796384789156,0,0.163503797819303,0,0.0955771563476108,0,0,0,0.0955771563476108,0.217538754627793,0.0729948539684629,0,0,0,0,0,0,0,0,0,0.0252062757946575,0,0,0,-0.349847949402483,0,-0.131831842300111,-0.0568589461625992,0,0,-0.232628352633041,0,0,0,0,0,0,-0.031340424028527,0,0,0,0,0,0,0,0.0477885781738054,0,0.0504125515893149,0,0,0,0,0,0,0,0,0.0955771563476108,0,0,0,0,0,0,-0.035324557231091,0,0,0,0,0.0504125515893149,0,0,-0.0979578962680575,0,0,0.0426895450320964,0,0,0.0248177361224561,0.0504125515893149,0,0,0.143009046999959,-0.0961032100756455,-0.033667177861778,0,0,0,-0.054385572482455,0.0955771563476108,0,-0.0329050193664387,0.0504125515893149,-0.0667773874189013,0.208286538151923,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.102910458759113,0,0,0,0,0,0,0,0,0,0,0,0.0252062757946575,0,0.0252062757946575,0,0,0,0,0,0,0,0,0,0,0,0,0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| |||
|rna_box=106 | |||
|rna_catalog_number= | |||
|rna_concentration=2.33779 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.8 | |||
|rna_od260/280=2.06 | |||
|rna_position=D4 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=106D4 | |||
|rna_weight_ug=58.44475 | |||
|sample_age=33 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=RCB1878 | |||
|sample_cell_line=RPMI1788 | |||
|sample_cell_lot= | |||
|sample_cell_type=b cell | |||
|sample_collaboration=Yukio Nakamura (RIKEN BRC) | |||
|sample_company=RIKEN Bioresource centre | |||
|sample_description= | |||
|sample_dev_stage=33 year old adult | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.79178973060457e-257!GO:0043227;membrane-bound organelle;5.73962191547471e-225!GO:0043231;intracellular membrane-bound organelle;1.96502584815142e-224!GO:0043226;organelle;9.68553667240518e-217!GO:0043229;intracellular organelle;7.70759658740794e-216!GO:0005737;cytoplasm;7.72023872576007e-170!GO:0044422;organelle part;1.11712337070767e-152!GO:0044446;intracellular organelle part;2.87455472282423e-150!GO:0044444;cytoplasmic part;3.0709876402751e-116!GO:0005634;nucleus;1.93713129231787e-111!GO:0032991;macromolecular complex;2.30829965072251e-109!GO:0044237;cellular metabolic process;1.77604422326241e-108!GO:0044238;primary metabolic process;2.2199504919516e-108!GO:0043170;macromolecule metabolic process;1.78851687218635e-103!GO:0030529;ribonucleoprotein complex;6.88089624366771e-92!GO:0044428;nuclear part;4.33537260606365e-91!GO:0003723;RNA binding;2.57152472285822e-87!GO:0043233;organelle lumen;1.54524799382112e-85!GO:0031974;membrane-enclosed lumen;1.54524799382112e-85!GO:0005515;protein binding;9.68401563817747e-74!GO:0005739;mitochondrion;6.95590817154533e-72!GO:0043283;biopolymer metabolic process;9.83637192877474e-68!GO:0006412;translation;8.99331966815355e-65!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.67607986086481e-62!GO:0010467;gene expression;1.86460787087705e-59!GO:0006396;RNA processing;3.38476106017134e-58!GO:0043234;protein complex;8.18598204674077e-56!GO:0031981;nuclear lumen;3.69673465454004e-53!GO:0005840;ribosome;9.07260779466974e-53!GO:0019538;protein metabolic process;8.18578284970475e-51!GO:0044429;mitochondrial part;4.37182787619747e-49!GO:0016071;mRNA metabolic process;1.2108930712864e-47!GO:0031090;organelle membrane;2.99383287937519e-47!GO:0031967;organelle envelope;3.47731400080568e-47!GO:0031975;envelope;9.10411801645412e-47!GO:0009059;macromolecule biosynthetic process;3.19514707822088e-46!GO:0003735;structural constituent of ribosome;9.49077459058897e-46!GO:0044267;cellular protein metabolic process;2.08151780151435e-45!GO:0006259;DNA metabolic process;3.8220526656119e-45!GO:0044260;cellular macromolecule metabolic process;9.03912453080785e-45!GO:0009058;biosynthetic process;1.75927560574094e-44!GO:0044249;cellular biosynthetic process;6.91072416128783e-44!GO:0033036;macromolecule localization;1.49444298678871e-43!GO:0003676;nucleic acid binding;2.25038859334512e-42!GO:0006397;mRNA processing;8.45660711965937e-42!GO:0008380;RNA splicing;1.30195125620928e-41!GO:0033279;ribosomal subunit;1.20197086927953e-40!GO:0015031;protein transport;1.60301041036107e-40!GO:0016043;cellular component organization and biogenesis;3.72571187175056e-40!GO:0008104;protein localization;3.24890086147722e-39!GO:0045184;establishment of protein localization;6.89334567214349e-39!GO:0006996;organelle organization and biogenesis;2.33521540611711e-36!GO:0005829;cytosol;2.39929493168974e-36!GO:0046907;intracellular transport;4.47856261308552e-36!GO:0022613;ribonucleoprotein complex biogenesis and assembly;8.67413040279923e-35!GO:0065003;macromolecular complex assembly;2.59531485670213e-34!GO:0005654;nucleoplasm;7.91838433618627e-34!GO:0007049;cell cycle;8.85018764261036e-33!GO:0000166;nucleotide binding;3.45508987999619e-32!GO:0043228;non-membrane-bound organelle;7.20213148512338e-32!GO:0043232;intracellular non-membrane-bound organelle;7.20213148512338e-32!GO:0006886;intracellular protein transport;7.7710081105446e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.83286572292961e-30!GO:0016070;RNA metabolic process;1.01403738282915e-29!GO:0005740;mitochondrial envelope;1.01403738282915e-29!GO:0006974;response to DNA damage stimulus;1.36356991561791e-29!GO:0005681;spliceosome;4.13434645111261e-29!GO:0022607;cellular component assembly;4.84928137574782e-29!GO:0019866;organelle inner membrane;3.72049456968448e-28!GO:0044445;cytosolic part;5.90607373746977e-28!GO:0031966;mitochondrial membrane;1.82796584075166e-27!GO:0051649;establishment of cellular localization;2.01110079481908e-27!GO:0051641;cellular localization;9.88808981521293e-27!GO:0022402;cell cycle process;1.34419598859327e-26!GO:0005743;mitochondrial inner membrane;1.37253938159394e-25!GO:0044451;nucleoplasm part;2.52712285589428e-25!GO:0005694;chromosome;1.89848087009953e-24!GO:0006281;DNA repair;2.05462260809652e-24!GO:0000278;mitotic cell cycle;2.60722447089656e-23!GO:0017076;purine nucleotide binding;2.70532857173684e-23!GO:0006512;ubiquitin cycle;2.96521994481891e-23!GO:0032553;ribonucleotide binding;3.69987860773224e-23!GO:0032555;purine ribonucleotide binding;3.69987860773224e-23!GO:0006915;apoptosis;4.13029772501988e-23!GO:0012501;programmed cell death;4.43274480863072e-23!GO:0031980;mitochondrial lumen;7.32649536959987e-23!GO:0005759;mitochondrial matrix;7.32649536959987e-23!GO:0016874;ligase activity;4.19280681596426e-22!GO:0044265;cellular macromolecule catabolic process;5.31745453482206e-22!GO:0016462;pyrophosphatase activity;7.94554183608819e-22!GO:0044427;chromosomal part;8.3168703616187e-22!GO:0005524;ATP binding;8.68622172581942e-22!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;9.82217869083072e-22!GO:0017111;nucleoside-triphosphatase activity;1.10390081798376e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;1.29105783096084e-21!GO:0015935;small ribosomal subunit;1.59621055738937e-21!GO:0032559;adenyl ribonucleotide binding;3.38092513933781e-21!GO:0030554;adenyl nucleotide binding;3.52505726620058e-21!GO:0005730;nucleolus;4.34831275724742e-21!GO:0012505;endomembrane system;7.06247401046645e-21!GO:0006119;oxidative phosphorylation;1.12128936487502e-20!GO:0022403;cell cycle phase;1.49821392101018e-20!GO:0051276;chromosome organization and biogenesis;2.01924416017061e-20!GO:0022618;protein-RNA complex assembly;2.24827754682418e-20!GO:0015934;large ribosomal subunit;3.29125087275319e-20!GO:0008219;cell death;4.58485498108684e-20!GO:0016265;death;4.58485498108684e-20!GO:0000087;M phase of mitotic cell cycle;4.58485498108684e-20!GO:0044455;mitochondrial membrane part;7.5227465039454e-20!GO:0007067;mitosis;7.92111676589851e-20!GO:0006457;protein folding;2.76892855076818e-19!GO:0019941;modification-dependent protein catabolic process;4.09165027040974e-19!GO:0043632;modification-dependent macromolecule catabolic process;4.09165027040974e-19!GO:0051603;proteolysis involved in cellular protein catabolic process;5.55514298509994e-19!GO:0009719;response to endogenous stimulus;5.81666748010727e-19!GO:0005635;nuclear envelope;5.81666748010727e-19!GO:0043285;biopolymer catabolic process;6.35172073741321e-19!GO:0006511;ubiquitin-dependent protein catabolic process;1.0243212190938e-18!GO:0008134;transcription factor binding;1.59552463146002e-18!GO:0000279;M phase;1.75436167961809e-18!GO:0044257;cellular protein catabolic process;1.83660013040796e-18!GO:0009057;macromolecule catabolic process;2.06760498031334e-18!GO:0006260;DNA replication;1.50693656190182e-17!GO:0051301;cell division;4.26195452357362e-17!GO:0044248;cellular catabolic process;5.65081411997322e-17!GO:0043412;biopolymer modification;6.26958497126589e-17!GO:0005783;endoplasmic reticulum;6.95691074655054e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.85826130525066e-16!GO:0000502;proteasome complex (sensu Eukaryota);4.14043527379358e-16!GO:0031965;nuclear membrane;4.16436906311846e-16!GO:0016604;nuclear body;4.31960103908704e-16!GO:0006605;protein targeting;5.08677520429209e-16!GO:0005746;mitochondrial respiratory chain;5.09345429195644e-16!GO:0016887;ATPase activity;5.73816650875022e-16!GO:0042623;ATPase activity, coupled;5.74886670571477e-16!GO:0008135;translation factor activity, nucleic acid binding;1.66388145514748e-15!GO:0004386;helicase activity;2.26073011293471e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.66381435778022e-15!GO:0042254;ribosome biogenesis and assembly;4.80352957010108e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;4.96018288194691e-15!GO:0000375;RNA splicing, via transesterification reactions;4.96018288194691e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.96018288194691e-15!GO:0006325;establishment and/or maintenance of chromatin architecture;6.59452524836681e-15!GO:0006913;nucleocytoplasmic transport;1.01843486868522e-14!GO:0005761;mitochondrial ribosome;1.34756998376581e-14!GO:0000313;organellar ribosome;1.34756998376581e-14!GO:0042981;regulation of apoptosis;1.37238512434592e-14!GO:0030163;protein catabolic process;1.51115445139416e-14!GO:0006464;protein modification process;1.91579941380082e-14!GO:0044432;endoplasmic reticulum part;2.34340882396861e-14!GO:0043067;regulation of programmed cell death;2.538556568588e-14!GO:0006323;DNA packaging;2.57870186920571e-14!GO:0051169;nuclear transport;2.81011941693768e-14!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.82870335115087e-14!GO:0051082;unfolded protein binding;3.51582519703696e-14!GO:0051186;cofactor metabolic process;4.08309470460815e-14!GO:0050136;NADH dehydrogenase (quinone) activity;7.69418177018783e-14!GO:0003954;NADH dehydrogenase activity;7.69418177018783e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;7.69418177018783e-14!GO:0051726;regulation of cell cycle;1.1200087212163e-13!GO:0044453;nuclear membrane part;1.2163879480052e-13!GO:0048770;pigment granule;1.30206567847069e-13!GO:0042470;melanosome;1.30206567847069e-13!GO:0043687;post-translational protein modification;1.40003369870092e-13!GO:0000074;regulation of progression through cell cycle;1.95211175403876e-13!GO:0050794;regulation of cellular process;6.68185985107015e-13!GO:0006413;translational initiation;6.69995426082285e-13!GO:0003712;transcription cofactor activity;1.05248731629341e-12!GO:0042775;organelle ATP synthesis coupled electron transport;1.33954174981184e-12!GO:0042773;ATP synthesis coupled electron transport;1.33954174981184e-12!GO:0003743;translation initiation factor activity;2.86518411200094e-12!GO:0006446;regulation of translational initiation;3.08284155166514e-12!GO:0030964;NADH dehydrogenase complex (quinone);4.61387320405913e-12!GO:0045271;respiratory chain complex I;4.61387320405913e-12!GO:0005747;mitochondrial respiratory chain complex I;4.61387320405913e-12!GO:0008026;ATP-dependent helicase activity;5.22498520915626e-12!GO:0016607;nuclear speck;5.67128366859597e-12!GO:0006732;coenzyme metabolic process;5.98197178298058e-12!GO:0006403;RNA localization;6.52282702905553e-12!GO:0050657;nucleic acid transport;6.78092210578112e-12!GO:0051236;establishment of RNA localization;6.78092210578112e-12!GO:0050658;RNA transport;6.78092210578112e-12!GO:0005643;nuclear pore;7.06785862570959e-12!GO:0006399;tRNA metabolic process;7.19679725505067e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;9.38662897715224e-12!GO:0051246;regulation of protein metabolic process;1.11002707781095e-11!GO:0048193;Golgi vesicle transport;1.84068372520669e-11!GO:0006333;chromatin assembly or disassembly;2.21116618761867e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.31834821777046e-11!GO:0065002;intracellular protein transport across a membrane;2.48556727393709e-11!GO:0000785;chromatin;3.31318080313443e-11!GO:0005789;endoplasmic reticulum membrane;3.34626148346056e-11!GO:0008639;small protein conjugating enzyme activity;4.47526687726944e-11!GO:0016568;chromatin modification;7.53077368894795e-11!GO:0004842;ubiquitin-protein ligase activity;8.79999369150458e-11!GO:0017038;protein import;9.53990764878991e-11!GO:0065004;protein-DNA complex assembly;9.98778604510486e-11!GO:0016779;nucleotidyltransferase activity;1.1383624578845e-10!GO:0006366;transcription from RNA polymerase II promoter;1.17673131711188e-10!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.36825827379723e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.45378401205538e-10!GO:0019787;small conjugating protein ligase activity;2.01071613531549e-10!GO:0006364;rRNA processing;2.55383221857078e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.85478337501021e-10!GO:0016072;rRNA metabolic process;3.92096212377509e-10!GO:0009056;catabolic process;4.60606007444896e-10!GO:0005794;Golgi apparatus;4.68144254137703e-10!GO:0009259;ribonucleotide metabolic process;4.76526597741512e-10!GO:0051028;mRNA transport;5.02214878119398e-10!GO:0006916;anti-apoptosis;5.35224267092232e-10!GO:0006163;purine nucleotide metabolic process;6.89545385935271e-10!GO:0046930;pore complex;6.89545385935271e-10!GO:0006164;purine nucleotide biosynthetic process;8.93540815952843e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;9.50350713291429e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.43388096866606e-09!GO:0004812;aminoacyl-tRNA ligase activity;1.43388096866606e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.43388096866606e-09!GO:0019222;regulation of metabolic process;1.64274124765597e-09!GO:0043069;negative regulation of programmed cell death;1.72066891599404e-09!GO:0043066;negative regulation of apoptosis;1.86200657713379e-09!GO:0043038;amino acid activation;1.97328209906942e-09!GO:0006418;tRNA aminoacylation for protein translation;1.97328209906942e-09!GO:0043039;tRNA aminoacylation;1.97328209906942e-09!GO:0009260;ribonucleotide biosynthetic process;2.03919633301447e-09!GO:0043566;structure-specific DNA binding;2.90572869588159e-09!GO:0009055;electron carrier activity;3.07375257024778e-09!GO:0006261;DNA-dependent DNA replication;3.69954223957053e-09!GO:0003697;single-stranded DNA binding;4.17481721428863e-09!GO:0009615;response to virus;4.66409861439847e-09!GO:0007249;I-kappaB kinase/NF-kappaB cascade;5.54118197329294e-09!GO:0008565;protein transporter activity;5.71694524224649e-09!GO:0006461;protein complex assembly;5.84703071573093e-09!GO:0009150;purine ribonucleotide metabolic process;6.66909000120375e-09!GO:0016881;acid-amino acid ligase activity;8.03170456469511e-09!GO:0009152;purine ribonucleotide biosynthetic process;8.89451981179687e-09!GO:0050789;regulation of biological process;9.48617664659067e-09!GO:0051188;cofactor biosynthetic process;1.17891914767962e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.45482812317398e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.00533365926321e-08!GO:0045333;cellular respiration;2.31921709872715e-08!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.38222192460028e-08!GO:0007005;mitochondrion organization and biogenesis;2.38546806226206e-08!GO:0009060;aerobic respiration;2.66934403440237e-08!GO:0006888;ER to Golgi vesicle-mediated transport;3.91694416305595e-08!GO:0005819;spindle;4.79747558570595e-08!GO:0005793;ER-Golgi intermediate compartment;4.81866050388726e-08!GO:0032446;protein modification by small protein conjugation;5.36568821739753e-08!GO:0051170;nuclear import;5.47076149231939e-08!GO:0000775;chromosome, pericentric region;6.04494113883202e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;6.85889024553792e-08!GO:0006793;phosphorus metabolic process;7.10745949207028e-08!GO:0006796;phosphate metabolic process;7.10745949207028e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;9.48626817974165e-08!GO:0019829;cation-transporting ATPase activity;1.02702875124907e-07!GO:0006417;regulation of translation;1.04113365261137e-07!GO:0016787;hydrolase activity;1.17246411960453e-07!GO:0003713;transcription coactivator activity;1.23821256951705e-07!GO:0006606;protein import into nucleus;1.32574253772527e-07!GO:0005839;proteasome core complex (sensu Eukaryota);1.38551780284794e-07!GO:0016567;protein ubiquitination;1.44857124415969e-07!GO:0030120;vesicle coat;1.48545171289073e-07!GO:0030662;coated vesicle membrane;1.48545171289073e-07!GO:0015986;ATP synthesis coupled proton transport;1.65114824711892e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.65114824711892e-07!GO:0009108;coenzyme biosynthetic process;1.72314065244069e-07!GO:0016192;vesicle-mediated transport;1.87525614400874e-07!GO:0016563;transcription activator activity;2.09911959165446e-07!GO:0031323;regulation of cellular metabolic process;2.15487600787349e-07!GO:0006310;DNA recombination;2.77268920899395e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.92675658179544e-07!GO:0007243;protein kinase cascade;2.92675658179544e-07!GO:0016740;transferase activity;3.71396271949961e-07!GO:0048475;coated membrane;4.04308583289314e-07!GO:0030117;membrane coat;4.04308583289314e-07!GO:0000075;cell cycle checkpoint;4.52783694798576e-07!GO:0030532;small nuclear ribonucleoprotein complex;4.69503138344972e-07!GO:0009142;nucleoside triphosphate biosynthetic process;4.92812827061586e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.92812827061586e-07!GO:0019899;enzyme binding;5.4624117616209e-07!GO:0008094;DNA-dependent ATPase activity;5.62915084847191e-07!GO:0016310;phosphorylation;5.84172422763139e-07!GO:0006334;nucleosome assembly;5.86042943496783e-07!GO:0004298;threonine endopeptidase activity;6.42249862671215e-07!GO:0006099;tricarboxylic acid cycle;7.37057965310625e-07!GO:0046356;acetyl-CoA catabolic process;7.37057965310625e-07!GO:0000245;spliceosome assembly;7.95318752254288e-07!GO:0009199;ribonucleoside triphosphate metabolic process;8.36950378343068e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;8.64614979716418e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;8.64614979716418e-07!GO:0009141;nucleoside triphosphate metabolic process;9.13924907120813e-07!GO:0031497;chromatin assembly;1.015941141666e-06!GO:0005813;centrosome;1.09631726600145e-06!GO:0045259;proton-transporting ATP synthase complex;1.15694813700219e-06!GO:0009117;nucleotide metabolic process;1.19779437453137e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.42583495954108e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.42583495954108e-06!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.45755753128342e-06!GO:0005657;replication fork;1.47852571799198e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.56247526689579e-06!GO:0006084;acetyl-CoA metabolic process;1.69840336875039e-06!GO:0006754;ATP biosynthetic process;1.77683002572475e-06!GO:0006753;nucleoside phosphate metabolic process;1.77683002572475e-06!GO:0043065;positive regulation of apoptosis;2.13703464658205e-06!GO:0048523;negative regulation of cellular process;2.60611362354658e-06!GO:0005815;microtubule organizing center;2.95236018016726e-06!GO:0065009;regulation of a molecular function;2.96248565168389e-06!GO:0006613;cotranslational protein targeting to membrane;3.10018001879823e-06!GO:0043068;positive regulation of programmed cell death;3.29952052107247e-06!GO:0015630;microtubule cytoskeleton;3.37232773315802e-06!GO:0006752;group transfer coenzyme metabolic process;3.66776338802611e-06!GO:0007051;spindle organization and biogenesis;3.89993752940785e-06!GO:0003724;RNA helicase activity;3.9435499210776e-06!GO:0046034;ATP metabolic process;4.0834805852957e-06!GO:0051168;nuclear export;5.02231992193496e-06!GO:0031326;regulation of cellular biosynthetic process;5.88860947233588e-06!GO:0006401;RNA catabolic process;6.8549806652677e-06!GO:0051789;response to protein stimulus;7.14063361432514e-06!GO:0006986;response to unfolded protein;7.14063361432514e-06!GO:0005770;late endosome;7.67167775865336e-06!GO:0007088;regulation of mitosis;8.35631793039849e-06!GO:0009109;coenzyme catabolic process;8.4374491193445e-06!GO:0006917;induction of apoptosis;8.81064943239052e-06!GO:0005768;endosome;8.99873942152332e-06!GO:0051187;cofactor catabolic process;1.00082412943941e-05!GO:0006350;transcription;1.06138787315773e-05!GO:0003899;DNA-directed RNA polymerase activity;1.16242224337544e-05!GO:0016469;proton-transporting two-sector ATPase complex;1.24765648871043e-05!GO:0010468;regulation of gene expression;1.2962997814503e-05!GO:0007059;chromosome segregation;1.30771242302887e-05!GO:0008632;apoptotic program;1.30968693126511e-05!GO:0006950;response to stress;1.3174263426524e-05!GO:0012502;induction of programmed cell death;1.36984162762464e-05!GO:0051325;interphase;1.80248743179594e-05!GO:0000151;ubiquitin ligase complex;2.02977098808286e-05!GO:0006302;double-strand break repair;2.26380852222179e-05!GO:0051329;interphase of mitotic cell cycle;2.29051966004398e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.29956623079976e-05!GO:0031072;heat shock protein binding;2.47143332399294e-05!GO:0065007;biological regulation;2.49610819277834e-05!GO:0048519;negative regulation of biological process;2.87377543473572e-05!GO:0048522;positive regulation of cellular process;2.97324962475916e-05!GO:0016564;transcription repressor activity;3.03314324666576e-05!GO:0006402;mRNA catabolic process;3.10949097068161e-05!GO:0005798;Golgi-associated vesicle;3.30118571160486e-05!GO:0051427;hormone receptor binding;3.95897467948717e-05!GO:0009165;nucleotide biosynthetic process;4.46103283065399e-05!GO:0045786;negative regulation of progression through cell cycle;4.46673034371385e-05!GO:0005762;mitochondrial large ribosomal subunit;4.56017195851009e-05!GO:0000315;organellar large ribosomal subunit;4.56017195851009e-05!GO:0009889;regulation of biosynthetic process;5.28239881710371e-05!GO:0005667;transcription factor complex;5.28555459809654e-05!GO:0051052;regulation of DNA metabolic process;5.44366114132687e-05!GO:0016853;isomerase activity;5.60833001371232e-05!GO:0004527;exonuclease activity;6.09287684660679e-05!GO:0043021;ribonucleoprotein binding;6.09287684660679e-05!GO:0043623;cellular protein complex assembly;7.23966869158559e-05!GO:0035257;nuclear hormone receptor binding;7.34109844779762e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.97785883325274e-05!GO:0003924;GTPase activity;8.11210236327649e-05!GO:0005048;signal sequence binding;8.43523609390407e-05!GO:0000776;kinetochore;8.53568116962262e-05!GO:0007006;mitochondrial membrane organization and biogenesis;8.91405892341277e-05!GO:0003690;double-stranded DNA binding;9.84931442400281e-05!GO:0003678;DNA helicase activity;0.000100082712396032!GO:0003714;transcription corepressor activity;0.000101165079829228!GO:0007093;mitotic cell cycle checkpoint;0.000107672539909791!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000117836918170348!GO:0000314;organellar small ribosomal subunit;0.000120855935553095!GO:0005763;mitochondrial small ribosomal subunit;0.000120855935553095!GO:0007242;intracellular signaling cascade;0.000124650973871597!GO:0030867;rough endoplasmic reticulum membrane;0.00012538898080404!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000127066551278345!GO:0006414;translational elongation;0.000131184099091089!GO:0004518;nuclease activity;0.000133141917905025!GO:0008186;RNA-dependent ATPase activity;0.000143485416101672!GO:0044440;endosomal part;0.000154959134643037!GO:0010008;endosome membrane;0.000154959134643037!GO:0003684;damaged DNA binding;0.000175351378227981!GO:0016363;nuclear matrix;0.000178433517720934!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000179261333488799!GO:0015399;primary active transmembrane transporter activity;0.000179261333488799!GO:0006612;protein targeting to membrane;0.000192368197713069!GO:0044431;Golgi apparatus part;0.000194914220629414!GO:0030658;transport vesicle membrane;0.000218899029830843!GO:0006091;generation of precursor metabolites and energy;0.000227272278216627!GO:0008654;phospholipid biosynthetic process;0.000227732096163455!GO:0009967;positive regulation of signal transduction;0.000232771869884557!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00023953101929812!GO:0045454;cell redox homeostasis;0.000242511402741733!GO:0003677;DNA binding;0.000252182447118189!GO:0006352;transcription initiation;0.000258872836377311!GO:0000323;lytic vacuole;0.000265699367037402!GO:0005764;lysosome;0.000265699367037402!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00027745496267633!GO:0003682;chromatin binding;0.000278744377627277!GO:0031324;negative regulation of cellular metabolic process;0.000284662255355526!GO:0005885;Arp2/3 protein complex;0.000300505591862885!GO:0005525;GTP binding;0.000313748430667901!GO:0005773;vacuole;0.000327593801468095!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000329756213835135!GO:0003729;mRNA binding;0.000354885993058085!GO:0043681;protein import into mitochondrion;0.000363117134000405!GO:0032774;RNA biosynthetic process;0.000393108417816831!GO:0005788;endoplasmic reticulum lumen;0.000398177753812263!GO:0051252;regulation of RNA metabolic process;0.000414855801956838!GO:0008033;tRNA processing;0.000419337563104166!GO:0004004;ATP-dependent RNA helicase activity;0.000435160371405907!GO:0031968;organelle outer membrane;0.000444280396058753!GO:0031970;organelle envelope lumen;0.000444280396058753!GO:0006383;transcription from RNA polymerase III promoter;0.000449966186346097!GO:0006351;transcription, DNA-dependent;0.000467830138664935!GO:0005741;mitochondrial outer membrane;0.000520637646273381!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000539102511121083!GO:0008637;apoptotic mitochondrial changes;0.000583438407359027!GO:0016491;oxidoreductase activity;0.000597473217446893!GO:0006839;mitochondrial transport;0.000617662047938671!GO:0050790;regulation of catalytic activity;0.000627889775390924!GO:0019867;outer membrane;0.000635244135159352!GO:0004674;protein serine/threonine kinase activity;0.000635244135159352!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000647438229329723!GO:0016251;general RNA polymerase II transcription factor activity;0.000696432938423203!GO:0000786;nucleosome;0.000697055533556627!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000719914936628186!GO:0006611;protein export from nucleus;0.000759277443374898!GO:0030880;RNA polymerase complex;0.000759968165005924!GO:0030660;Golgi-associated vesicle membrane;0.000759968165005924!GO:0006891;intra-Golgi vesicle-mediated transport;0.000766472535047359!GO:0016741;transferase activity, transferring one-carbon groups;0.000770717917115569!GO:0044452;nucleolar part;0.000794654137816648!GO:0005758;mitochondrial intermembrane space;0.0008015600203037!GO:0042770;DNA damage response, signal transduction;0.000801996584727495!GO:0048500;signal recognition particle;0.000819731814597614!GO:0032508;DNA duplex unwinding;0.000821006504154316!GO:0032392;DNA geometric change;0.000821006504154316!GO:0006520;amino acid metabolic process;0.000840965182940937!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000981407225114947!GO:0030127;COPII vesicle coat;0.000999484990648277!GO:0012507;ER to Golgi transport vesicle membrane;0.000999484990648277!GO:0030134;ER to Golgi transport vesicle;0.00104330711356128!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00112037917187294!GO:0043488;regulation of mRNA stability;0.00118940796611848!GO:0043487;regulation of RNA stability;0.00118940796611848!GO:0019843;rRNA binding;0.00119662035108471!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00120916557166631!GO:0000428;DNA-directed RNA polymerase complex;0.00120916557166631!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00123508276210653!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00123508276210653!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00123508276210653!GO:0006405;RNA export from nucleus;0.00123737667372934!GO:0032200;telomere organization and biogenesis;0.00132668055261518!GO:0000723;telomere maintenance;0.00132668055261518!GO:0046822;regulation of nucleocytoplasmic transport;0.00134691482487707!GO:0007052;mitotic spindle organization and biogenesis;0.00137849432037291!GO:0006818;hydrogen transport;0.00140422091933249!GO:0006626;protein targeting to mitochondrion;0.00142511378505839!GO:0000049;tRNA binding;0.00145388770255979!GO:0030384;phosphoinositide metabolic process;0.00150422448269245!GO:0008139;nuclear localization sequence binding;0.00151456874276582!GO:0008168;methyltransferase activity;0.00159027725310372!GO:0016126;sterol biosynthetic process;0.00159509354471488!GO:0051223;regulation of protein transport;0.00160604893451754!GO:0008312;7S RNA binding;0.00161396632974296!GO:0006650;glycerophospholipid metabolic process;0.0016542215483262!GO:0006268;DNA unwinding during replication;0.00167725473495966!GO:0006338;chromatin remodeling;0.00167725473495966!GO:0048471;perinuclear region of cytoplasm;0.00175622342654874!GO:0051920;peroxiredoxin activity;0.00178548076269612!GO:0006984;ER-nuclear signaling pathway;0.00188374524010817!GO:0022411;cellular component disassembly;0.00192859662703133!GO:0030663;COPI coated vesicle membrane;0.00194794248324002!GO:0030126;COPI vesicle coat;0.00194794248324002!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00194794248324002!GO:0032561;guanyl ribonucleotide binding;0.00198765049691183!GO:0019001;guanyl nucleotide binding;0.00198765049691183!GO:0006007;glucose catabolic process;0.00199088389233232!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00200114622025734!GO:0030433;ER-associated protein catabolic process;0.00200114622025734!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.00200114622025734!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00202424906572407!GO:0045047;protein targeting to ER;0.00202424906572407!GO:0048518;positive regulation of biological process;0.00205151110362393!GO:0000228;nuclear chromosome;0.00205151110362393!GO:0003711;transcription elongation regulator activity;0.00205885374725595!GO:0015992;proton transport;0.00206757552560641!GO:0009892;negative regulation of metabolic process;0.00207658993968488!GO:0016859;cis-trans isomerase activity;0.00208059193407362!GO:0000139;Golgi membrane;0.00209740032661076!GO:0043492;ATPase activity, coupled to movement of substances;0.00210443823083465!GO:0046483;heterocycle metabolic process;0.00215618706587641!GO:0005637;nuclear inner membrane;0.00216450736743497!GO:0033116;ER-Golgi intermediate compartment membrane;0.00217266668044803!GO:0019752;carboxylic acid metabolic process;0.00223296908333874!GO:0042113;B cell activation;0.00230299155425025!GO:0022415;viral reproductive process;0.00240544291562923!GO:0045449;regulation of transcription;0.0024269465738412!GO:0006595;polyamine metabolic process;0.00243874785889532!GO:0018193;peptidyl-amino acid modification;0.00246784748244606!GO:0047485;protein N-terminus binding;0.00246784748244606!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00246784748244606!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00246784748244606!GO:0005684;U2-dependent spliceosome;0.00247449666418225!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00249722990308203!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00267463372934098!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00267463372934098!GO:0045941;positive regulation of transcription;0.00271525128905284!GO:0019783;small conjugating protein-specific protease activity;0.00273803249275882!GO:0006082;organic acid metabolic process;0.00276218053964562!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00283171365701276!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00304426769452493!GO:0043596;nuclear replication fork;0.00310202736559988!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00311876744500387!GO:0033673;negative regulation of kinase activity;0.0031230193919112!GO:0006469;negative regulation of protein kinase activity;0.0031230193919112!GO:0005769;early endosome;0.00328595728471384!GO:0003725;double-stranded RNA binding;0.00329295736477526!GO:0051348;negative regulation of transferase activity;0.0033298777540182!GO:0008408;3'-5' exonuclease activity;0.00336298960108663!GO:0030137;COPI-coated vesicle;0.00347951763671221!GO:0042802;identical protein binding;0.00347951763671221!GO:0004576;oligosaccharyl transferase activity;0.00350526501902332!GO:0009124;nucleoside monophosphate biosynthetic process;0.0035526427163695!GO:0009123;nucleoside monophosphate metabolic process;0.0035526427163695!GO:0008234;cysteine-type peptidase activity;0.00356510720180317!GO:0007264;small GTPase mediated signal transduction;0.0038930961456456!GO:0015980;energy derivation by oxidation of organic compounds;0.00393994662022152!GO:0051235;maintenance of localization;0.00395352718626831!GO:0016197;endosome transport;0.00397274889794791!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00400520894217723!GO:0000922;spindle pole;0.00411192232204029!GO:0000059;protein import into nucleus, docking;0.00413756720491142!GO:0046489;phosphoinositide biosynthetic process;0.0041795117521883!GO:0006144;purine base metabolic process;0.00425812552019105!GO:0005876;spindle microtubule;0.00426914013422174!GO:0004843;ubiquitin-specific protease activity;0.00437387820847909!GO:0009116;nucleoside metabolic process;0.00443035127627239!GO:0016584;nucleosome positioning;0.00447778295496446!GO:0048468;cell development;0.00451265657733616!GO:0050662;coenzyme binding;0.00456254888537013!GO:0005791;rough endoplasmic reticulum;0.00472165079898192!GO:0016272;prefoldin complex;0.00476589729014324!GO:0030518;steroid hormone receptor signaling pathway;0.00478143814061584!GO:0008250;oligosaccharyl transferase complex;0.0050687028561538!GO:0031124;mRNA 3'-end processing;0.00528712256929139!GO:0009893;positive regulation of metabolic process;0.00534979483988549!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.00546686694510396!GO:0031982;vesicle;0.00546686694510396!GO:0004532;exoribonuclease activity;0.00548083496905905!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00548083496905905!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00560432369417376!GO:0003887;DNA-directed DNA polymerase activity;0.00560432369417376!GO:0004221;ubiquitin thiolesterase activity;0.00563663687707633!GO:0030521;androgen receptor signaling pathway;0.00566724588923381!GO:0035258;steroid hormone receptor binding;0.00577177681920852!GO:0000781;chromosome, telomeric region;0.00613778760972881!GO:0009112;nucleobase metabolic process;0.00617509195673065!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00622001534992583!GO:0031902;late endosome membrane;0.00622091936470092!GO:0022890;inorganic cation transmembrane transporter activity;0.00622091936470092!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00634921477595378!GO:0030968;unfolded protein response;0.00643932104024481!GO:0051087;chaperone binding;0.0064400819475678!GO:0030695;GTPase regulator activity;0.0064464369966362!GO:0006289;nucleotide-excision repair;0.00647735670019661!GO:0046649;lymphocyte activation;0.00647735670019661!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00647735670019661!GO:0015002;heme-copper terminal oxidase activity;0.00647735670019661!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00647735670019661!GO:0004129;cytochrome-c oxidase activity;0.00647735670019661!GO:0045185;maintenance of protein localization;0.00661697182497584!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00676108767689912!GO:0007265;Ras protein signal transduction;0.00677082111150156!GO:0003756;protein disulfide isomerase activity;0.00702759436261466!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.00702759436261466!GO:0043130;ubiquitin binding;0.00740395726215511!GO:0032182;small conjugating protein binding;0.00740395726215511!GO:0045045;secretory pathway;0.00746742679853409!GO:0006275;regulation of DNA replication;0.00768595023797965!GO:0051098;regulation of binding;0.00770402525913879!GO:0042393;histone binding;0.00773893648331258!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00779493879013366!GO:0015631;tubulin binding;0.00788522588189023!GO:0009161;ribonucleoside monophosphate metabolic process;0.00788522588189023!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00788522588189023!GO:0004003;ATP-dependent DNA helicase activity;0.00788995255689439!GO:0051338;regulation of transferase activity;0.0079227913890872!GO:0001836;release of cytochrome c from mitochondria;0.00816658329050084!GO:0030176;integral to endoplasmic reticulum membrane;0.00816658329050084!GO:0016481;negative regulation of transcription;0.00819056065554762!GO:0031988;membrane-bound vesicle;0.00825161622180781!GO:0046474;glycerophospholipid biosynthetic process;0.0085053617376765!GO:0046966;thyroid hormone receptor binding;0.00851150039408962!GO:0003702;RNA polymerase II transcription factor activity;0.00851150039408962!GO:0045893;positive regulation of transcription, DNA-dependent;0.00864969425113411!GO:0016790;thiolester hydrolase activity;0.00872711034120922!GO:0032984;macromolecular complex disassembly;0.0090013554058371!GO:0000209;protein polyubiquitination;0.00901763931094243!GO:0018196;peptidyl-asparagine modification;0.00915719968464956!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00915719968464956!GO:0042613;MHC class II protein complex;0.00920607193048575!GO:0006096;glycolysis;0.00930933949924686!GO:0000082;G1/S transition of mitotic cell cycle;0.00931408867515585!GO:0043022;ribosome binding;0.00931826682920955!GO:0006695;cholesterol biosynthetic process;0.00935301668006622!GO:0005083;small GTPase regulator activity;0.00942056865263848!GO:0000819;sister chromatid segregation;0.00943876537371302!GO:0051053;negative regulation of DNA metabolic process;0.00946102309717542!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00955976882297625!GO:0030133;transport vesicle;0.00974767736431973!GO:0031570;DNA integrity checkpoint;0.00974767736431973!GO:0006355;regulation of transcription, DNA-dependent;0.00979201493689283!GO:0043549;regulation of kinase activity;0.00990400455535055!GO:0006270;DNA replication initiation;0.00991386331884555!GO:0000287;magnesium ion binding;0.00999437035483885!GO:0032940;secretion by cell;0.0102155880315093!GO:0031252;leading edge;0.0103776052818238!GO:0032507;maintenance of cellular protein localization;0.0104316281999609!GO:0008047;enzyme activator activity;0.0107705372117552!GO:0008629;induction of apoptosis by intracellular signals;0.0109054409591904!GO:0009451;RNA modification;0.0109466824032147!GO:0044454;nuclear chromosome part;0.0110456259146185!GO:0030118;clathrin coat;0.0110571359716975!GO:0046365;monosaccharide catabolic process;0.0110991916606169!GO:0000339;RNA cap binding;0.0111052953817513!GO:0000070;mitotic sister chromatid segregation;0.0115899820229481!GO:0000725;recombinational repair;0.0118479031976214!GO:0000724;double-strand break repair via homologous recombination;0.0118479031976214!GO:0006376;mRNA splice site selection;0.0118560332718347!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0118560332718347!GO:0043284;biopolymer biosynthetic process;0.0123390572049108!GO:0031325;positive regulation of cellular metabolic process;0.0123893159089754!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0136491817419595!GO:0005096;GTPase activator activity;0.0136879690418045!GO:0005832;chaperonin-containing T-complex;0.0137930222724515!GO:0007050;cell cycle arrest;0.0137930222724515!GO:0008097;5S rRNA binding;0.0138279023667002!GO:0031123;RNA 3'-end processing;0.0139086422863772!GO:0003746;translation elongation factor activity;0.0139909116962038!GO:0006284;base-excision repair;0.0144225300593614!GO:0005669;transcription factor TFIID complex;0.0148402441561507!GO:0006607;NLS-bearing substrate import into nucleus;0.0149293103648848!GO:0031410;cytoplasmic vesicle;0.0151000229757233!GO:0043241;protein complex disassembly;0.0151000229757233!GO:0043601;nuclear replisome;0.0156335164809834!GO:0030894;replisome;0.0156335164809834!GO:0019320;hexose catabolic process;0.0160645246505788!GO:0000178;exosome (RNase complex);0.0166509165075336!GO:0009607;response to biotic stimulus;0.0169139857578964!GO:0005774;vacuolar membrane;0.0169585758170483!GO:0007010;cytoskeleton organization and biogenesis;0.0172025468101933!GO:0045859;regulation of protein kinase activity;0.0173400401794172!GO:0000152;nuclear ubiquitin ligase complex;0.0175127671422395!GO:0016407;acetyltransferase activity;0.0176179113420372!GO:0051336;regulation of hydrolase activity;0.0178997151363456!GO:0005765;lysosomal membrane;0.0179644256774404!GO:0048487;beta-tubulin binding;0.0183177999597776!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0184463006493463!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0184463006493463!GO:0009126;purine nucleoside monophosphate metabolic process;0.0184463006493463!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0184463006493463!GO:0031625;ubiquitin protein ligase binding;0.0184733298768225!GO:0008624;induction of apoptosis by extracellular signals;0.0186189852735616!GO:0007004;telomere maintenance via telomerase;0.0189490199836148!GO:0016023;cytoplasmic membrane-bound vesicle;0.0191857799796383!GO:0030262;apoptotic nuclear changes;0.0194800163473304!GO:0043414;biopolymer methylation;0.019539005022599!GO:0051539;4 iron, 4 sulfur cluster binding;0.0197090378237978!GO:0043087;regulation of GTPase activity;0.0197411911372813!GO:0032259;methylation;0.019810825578414!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0202234802890965!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.02025251452001!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0204153968278109!GO:0051651;maintenance of cellular localization;0.0205011938377756!GO:0031577;spindle checkpoint;0.0206023553947051!GO:0046164;alcohol catabolic process;0.0210914325967795!GO:0043624;cellular protein complex disassembly;0.0213381322322518!GO:0045947;negative regulation of translational initiation;0.0214519584339801!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0214783017173692!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0215071921963338!GO:0051656;establishment of organelle localization;0.0215483154327391!GO:0000726;non-recombinational repair;0.0219478959038529!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0231885405645095!GO:0000175;3'-5'-exoribonuclease activity;0.0232990862942368!GO:0031647;regulation of protein stability;0.0240704855390235!GO:0006378;mRNA polyadenylation;0.024338651619283!GO:0016788;hydrolase activity, acting on ester bonds;0.025181856406225!GO:0006519;amino acid and derivative metabolic process;0.025428421167506!GO:0005850;eukaryotic translation initiation factor 2 complex;0.025428421167506!GO:0030041;actin filament polymerization;0.0256208330929185!GO:0030522;intracellular receptor-mediated signaling pathway;0.0256208330929185!GO:0004536;deoxyribonuclease activity;0.0257458377290389!GO:0000738;DNA catabolic process, exonucleolytic;0.0259162163034372!GO:0000077;DNA damage checkpoint;0.0259459546906493!GO:0046467;membrane lipid biosynthetic process;0.0260836942204083!GO:0006643;membrane lipid metabolic process;0.0262486980431963!GO:0005663;DNA replication factor C complex;0.0262486980431963!GO:0006672;ceramide metabolic process;0.026488210820837!GO:0051051;negative regulation of transport;0.026488210820837!GO:0051881;regulation of mitochondrial membrane potential;0.026488210820837!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0265284751910121!GO:0006308;DNA catabolic process;0.0266165748600394!GO:0008180;signalosome;0.0268055889080929!GO:0006596;polyamine biosynthetic process;0.026811535268317!GO:0046902;regulation of mitochondrial membrane permeability;0.026811535268317!GO:0006220;pyrimidine nucleotide metabolic process;0.0271151178942705!GO:0030036;actin cytoskeleton organization and biogenesis;0.0280875896379811!GO:0019318;hexose metabolic process;0.0283406306866657!GO:0019058;viral infectious cycle;0.0288316236313323!GO:0046983;protein dimerization activity;0.0290143261141103!GO:0000792;heterochromatin;0.0296874626699204!GO:0008276;protein methyltransferase activity;0.0299967699016576!GO:0051540;metal cluster binding;0.0299967699016576!GO:0051536;iron-sulfur cluster binding;0.0299967699016576!GO:0006278;RNA-dependent DNA replication;0.0304268959140503!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0305310873367953!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0308013300641977!GO:0016791;phosphoric monoester hydrolase activity;0.0308428488810973!GO:0046979;TAP2 binding;0.0310728102191982!GO:0046977;TAP binding;0.0310728102191982!GO:0046978;TAP1 binding;0.0310728102191982!GO:0051092;activation of NF-kappaB transcription factor;0.0321778077512856!GO:0044450;microtubule organizing center part;0.0321958264051582!GO:0008156;negative regulation of DNA replication;0.0322479579516633!GO:0005784;translocon complex;0.032273856949941!GO:0046519;sphingoid metabolic process;0.0326798126297685!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.0327297586187094!GO:0035267;NuA4 histone acetyltransferase complex;0.0327448893949328!GO:0008320;protein transmembrane transporter activity;0.0328940525011824!GO:0030119;AP-type membrane coat adaptor complex;0.0330364651843129!GO:0006400;tRNA modification;0.0336329479114885!GO:0005996;monosaccharide metabolic process;0.0341362306401867!GO:0044437;vacuolar part;0.0341362306401867!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0350162868823261!GO:0009966;regulation of signal transduction;0.0361294606596326!GO:0019079;viral genome replication;0.0362571339821654!GO:0006497;protein amino acid lipidation;0.0365655456317765!GO:0043189;H4/H2A histone acetyltransferase complex;0.036822840065473!GO:0046426;negative regulation of JAK-STAT cascade;0.0370242170230612!GO:0006767;water-soluble vitamin metabolic process;0.0372254585078942!GO:0022884;macromolecule transmembrane transporter activity;0.0374324749766717!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0374324749766717!GO:0030125;clathrin vesicle coat;0.0374324749766717!GO:0030665;clathrin coated vesicle membrane;0.0374324749766717!GO:0030496;midbody;0.0374839822143453!GO:0006733;oxidoreduction coenzyme metabolic process;0.0376679106502899!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0377313675200189!GO:0046112;nucleobase biosynthetic process;0.0384602369397019!GO:0044262;cellular carbohydrate metabolic process;0.0385450542958651!GO:0000910;cytokinesis;0.0389396550408144!GO:0033367;protein localization in mast cell secretory granule;0.0393023000422521!GO:0033365;protein localization in organelle;0.0393023000422521!GO:0033371;T cell secretory granule organization and biogenesis;0.0393023000422521!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0393023000422521!GO:0033375;protease localization in T cell secretory granule;0.0393023000422521!GO:0042629;mast cell granule;0.0393023000422521!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0393023000422521!GO:0033364;mast cell secretory granule organization and biogenesis;0.0393023000422521!GO:0033380;granzyme B localization in T cell secretory granule;0.0393023000422521!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0393023000422521!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0393023000422521!GO:0033368;protease localization in mast cell secretory granule;0.0393023000422521!GO:0033366;protein localization in secretory granule;0.0393023000422521!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0393023000422521!GO:0033374;protein localization in T cell secretory granule;0.0393023000422521!GO:0009303;rRNA transcription;0.0400081465869574!GO:0005092;GDP-dissociation inhibitor activity;0.040053090635143!GO:0045069;regulation of viral genome replication;0.0403561186582205!GO:0000096;sulfur amino acid metabolic process;0.0405780587151402!GO:0000123;histone acetyltransferase complex;0.0407166121870025!GO:0000793;condensed chromosome;0.040962946164783!GO:0006740;NADPH regeneration;0.040962946164783!GO:0006098;pentose-phosphate shunt;0.040962946164783!GO:0017134;fibroblast growth factor binding;0.0412608333093832!GO:0030833;regulation of actin filament polymerization;0.0413675055525832!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0421415132524154!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0421415132524154!GO:0006118;electron transport;0.0427245977348482!GO:0008538;proteasome activator activity;0.0428040521197261!GO:0016301;kinase activity;0.0428154368164202!GO:0051287;NAD binding;0.0428243053849162!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0433538705437031!GO:0010257;NADH dehydrogenase complex assembly;0.0433538705437031!GO:0033108;mitochondrial respiratory chain complex assembly;0.0433538705437031!GO:0006983;ER overload response;0.0439996272745783!GO:0046128;purine ribonucleoside metabolic process;0.0440232033949724!GO:0042278;purine nucleoside metabolic process;0.0440232033949724!GO:0007017;microtubule-based process;0.0444284329166962!GO:0051101;regulation of DNA binding;0.0447903550757326!GO:0050681;androgen receptor binding;0.0449907101111995!GO:0033157;regulation of intracellular protein transport;0.0452238261828248!GO:0042306;regulation of protein import into nucleus;0.0452238261828248!GO:0009113;purine base biosynthetic process;0.0454168277252159!GO:0006406;mRNA export from nucleus;0.0454189006658849!GO:0043407;negative regulation of MAP kinase activity;0.0458057106278561!GO:0046982;protein heterodimerization activity;0.0458825300006797!GO:0032039;integrator complex;0.0459975962404454!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0460147537403043!GO:0016605;PML body;0.0463451669233197!GO:0006769;nicotinamide metabolic process;0.0464812282847637!GO:0006506;GPI anchor biosynthetic process;0.0467507484369611!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0471304593490723!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0471304593490723!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0471304593490723!GO:0005680;anaphase-promoting complex;0.0473529170579578!GO:0050871;positive regulation of B cell activation;0.0476141770263486!GO:0000119;mediator complex;0.0477065543642585!GO:0045321;leukocyte activation;0.047798682700043!GO:0043086;negative regulation of catalytic activity;0.0487153255614825!GO:0007021;tubulin folding;0.049240422522699!GO:0050178;phenylpyruvate tautomerase activity;0.0496350320842335!GO:0051090;regulation of transcription factor activity;0.0496677042680261 | |||
|sample_id=10427 | |||
|sample_note=machine failed, remainder reloaded, low amount | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=POU2F1..3:2.758278419;POU5F1:2.43290289398;HIF1A:2.38003687229;PAX6:1.61957834197;NFKB1_REL_RELA:1.60813867479;HOXA9_MEIS1:1.59914055545;NFY{A,B,C}:1.51508607029;IRF1,2:1.50826051587;VSX1,2:1.42891680921;ELF1,2,4:1.41661606178;EVI1:1.41464408118;AHR_ARNT_ARNT2:1.37646179247;CDX1,2,4:1.32308481494;MYB:1.27969215398;PITX1..3:1.27855159924;NKX6-1,2:1.23596464115;PAX8:1.20012814038;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.1775021433;IRF7:1.1761609463;ZBTB16:1.17109770714;DMAP1_NCOR{1,2}_SMARC:1.15652799866;TOPORS:1.09526762692;E2F1..5:1.08685415961;YY1:1.06102512226;MYOD1:1.0221771558;HES1:1.0133245455;ELK1,4_GABP{A,B1}:0.984789709165;FOXP1:0.950042757711;FOXA2:0.932984288937;HBP1_HMGB_SSRP1_UBTF:0.91559085024;BREu{core}:0.812453281506;PBX1:0.811463513658;NANOG{mouse}:0.801712287524;AIRE:0.755745581009;PAX3,7:0.75143888973;FOXP3:0.73715151091;PDX1:0.726908420661;SPI1:0.721525054693;TLX2:0.704558115146;LMO2:0.70107023242;FOXN1:0.693580226367;POU3F1..4:0.666765436112;RUNX1..3:0.652432171734;GATA6:0.642432950952;ATF5_CREB3:0.615352191023;OCT4_SOX2{dimer}:0.613082574369;TGIF1:0.595231254962;CREB1:0.587915996436;HSF1,2:0.578367036882;ZNF143:0.536175857712;ZEB1:0.494744059932;CUX2:0.487700931469;SPIB:0.47509033502;RXRA_VDR{dimer}:0.465809476613;NRF1:0.439151602253;NKX2-2,8:0.427734330503;PAX2:0.420778805303;ATF4:0.400943212443;POU1F1:0.38729789693;SNAI1..3:0.346937044632;ETS1,2:0.322081704814;HMGA1,2:0.267175238677;BPTF:0.223286421922;TP53:0.154821204042;NR5A1,2:0.154338396113;CDC5L:0.1502282087;SOX{8,9,10}:0.111479714564;STAT5{A,B}:0.0923130355427;MEF2{A,B,C,D}:0.0895582847903;CRX:0.0655788293082;HNF1A:0.0596602216813;GFI1:0.0550385889778;SREBF1,2:0.0209128562482;GCM1,2:-0.000724393792006;RFX2..5_RFXANK_RFXAP:-0.0173290415999;HNF4A_NR2F1,2:-0.0225229329906;bHLH_family:-0.0403136314252;HAND1,2:-0.0404599162844;PAX4:-0.0718319452478;HOX{A6,A7,B6,B7}:-0.0747910273551;PPARG:-0.0789207327933;EP300:-0.0812475787993;PRRX1,2:-0.0999198091184;ALX4:-0.100488260999;FOSL2:-0.108003601647;NFE2:-0.110913260722;FOX{F1,F2,J1}:-0.135256675518;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.152491982493;ATF6:-0.241035685048;SOX5:-0.247142466061;TEF:-0.247487585679;IKZF2:-0.257564199128;ZFP161:-0.266447824231;FOXQ1:-0.268918088997;NFATC1..3:-0.26945379572;HLF:-0.274386295654;NKX2-1,4:-0.27845008227;STAT1,3:-0.298357537755;PRDM1:-0.308355801442;ATF2:-0.309477694379;TBP:-0.313514281777;EBF1:-0.317396619775;SPZ1:-0.332918749183;RBPJ:-0.341079223535;ESR1:-0.35060962011;LEF1_TCF7_TCF7L1,2:-0.385672836381;RXR{A,B,G}:-0.388276280419;ARID5B:-0.401722369953;STAT2,4,6:-0.404128394761;SOX17:-0.412342598321;NKX3-2:-0.415993836536;NFIL3:-0.422268603771;SMAD1..7,9:-0.431924896795;RFX1:-0.43758087998;BACH2:-0.44824164199;NR6A1:-0.456492434745;ONECUT1,2:-0.465341750916;ZNF384:-0.475801850555;HOX{A4,D4}:-0.481598416143;FOX{I1,J2}:-0.489999120846;SRF:-0.490083045179;FOS_FOS{B,L1}_JUN{B,D}:-0.492040089099;FOXO1,3,4:-0.507844181563;NHLH1,2:-0.512705373309;CEBPA,B_DDIT3:-0.538036881488;EN1,2:-0.546553276415;NKX3-1:-0.556200091961;RORA:-0.58676177274;NANOG:-0.608385578316;AR:-0.611978460729;ZNF148:-0.631799697399;TFAP4:-0.650685085499;DBP:-0.654127093757;MAFB:-0.656629525861;GATA4:-0.660498012213;TFDP1:-0.675402526248;MYFfamily:-0.677563648713;JUN:-0.689962001908;RREB1:-0.704120655245;HOX{A5,B5}:-0.721961970144;GFI1B:-0.723135040086;ADNP_IRX_SIX_ZHX:-0.759615202593;POU6F1:-0.769193301935;TBX4,5:-0.78676127954;ESRRA:-0.803174948504;NR1H4:-0.82154938956;EGR1..3:-0.823713710387;ALX1:-0.868072873535;GLI1..3:-0.87805789328;SOX2:-0.884004215135;PATZ1:-0.896792650852;LHX3,4:-0.900718626094;NKX2-3_NKX2-5:-0.923484000901;MZF1:-0.932279701323;GTF2A1,2:-0.94648465595;MTE{core}:-0.952151934329;MYBL2:-0.955253372267;HIC1:-0.979726502839;UFEwm:-0.990995435503;PAX5:-1.01093617366;NFIX:-1.02738257208;REST:-1.04075286149;NFE2L2:-1.04528949865;MED-1{core}:-1.10685821386;MTF1:-1.12833974982;XCPE1{core}:-1.12846810645;GTF2I:-1.12977878151;FOX{D1,D2}:-1.13644305953;XBP1:-1.1644549462;ZNF423:-1.18860928799;IKZF1:-1.21119606221;ZIC1..3:-1.23928704785;KLF4:-1.23998918984;SP1:-1.24337503361;ZNF238:-1.26018956125;GZF1:-1.26485642119;NR3C1:-1.31249955219;TFCP2:-1.33341793236;ZBTB6:-1.36198834076;NFE2L1:-1.36958499756;PAX1,9:-1.37047349926;TEAD1:-1.37827844181;FOXD3:-1.40056943854;MAZ:-1.40263829222;TLX1..3_NFIC{dimer}:-1.42469152425;TFAP2{A,C}:-1.44691919081;HMX1:-1.45113544601;TAL1_TCF{3,4,12}:-1.46552536902;TFAP2B:-1.58535386231;FOXL1:-1.6915514992;FOXM1:-1.71699376185;T:-1.79748575043 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10427-106D4;search_select_hide=table117:FF:10427-106D4 | |||
}} | }} |
Latest revision as of 14:01, 3 June 2020
Name: | b cell line:RPMI1788 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs10744 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10744
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10744
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0136 |
10 | 10 | 0.0218 |
100 | 100 | 0.333 |
101 | 101 | 0.296 |
102 | 102 | 0.765 |
103 | 103 | 0.528 |
104 | 104 | 0.501 |
105 | 105 | 0.735 |
106 | 106 | 0.857 |
107 | 107 | 0.698 |
108 | 108 | 0.458 |
109 | 109 | 0.076 |
11 | 11 | 0.234 |
110 | 110 | 0.204 |
111 | 111 | 0.171 |
112 | 112 | 0.501 |
113 | 113 | 0.56 |
114 | 114 | 0.687 |
115 | 115 | 0.956 |
116 | 116 | 0.854 |
117 | 117 | 0.0263 |
118 | 118 | 0.0605 |
119 | 119 | 0.0908 |
12 | 12 | 0.996 |
120 | 120 | 0.929 |
121 | 121 | 0.407 |
122 | 122 | 0.599 |
123 | 123 | 2.36055e-4 |
124 | 124 | 0.152 |
125 | 125 | 0.529 |
126 | 126 | 0.176 |
127 | 127 | 0.316 |
128 | 128 | 0.613 |
129 | 129 | 0.809 |
13 | 13 | 0.0389 |
130 | 130 | 0.88 |
131 | 131 | 0.793 |
132 | 132 | 0.301 |
133 | 133 | 0.759 |
134 | 134 | 0.789 |
135 | 135 | 0.748 |
136 | 136 | 0.536 |
137 | 137 | 0.604 |
138 | 138 | 0.433 |
139 | 139 | 0.898 |
14 | 14 | 0.57 |
140 | 140 | 0.444 |
141 | 141 | 0.449 |
142 | 142 | 0.837 |
143 | 143 | 0.501 |
144 | 144 | 0.289 |
145 | 145 | 0.309 |
146 | 146 | 0.851 |
147 | 147 | 0.104 |
148 | 148 | 0.0547 |
149 | 149 | 0.26 |
15 | 15 | 0.132 |
150 | 150 | 0.731 |
151 | 151 | 0.451 |
152 | 152 | 0.146 |
153 | 153 | 0.534 |
154 | 154 | 0.991 |
155 | 155 | 0.0672 |
156 | 156 | 0.956 |
157 | 157 | 0.162 |
158 | 158 | 0.144 |
159 | 159 | 0.748 |
16 | 16 | 0.633 |
160 | 160 | 0.387 |
161 | 161 | 0.118 |
162 | 162 | 0.274 |
163 | 163 | 0.887 |
164 | 164 | 0.146 |
165 | 165 | 0.428 |
166 | 166 | 0.518 |
167 | 167 | 0.308 |
168 | 168 | 0.674 |
169 | 169 | 0.815 |
17 | 17 | 0.886 |
18 | 18 | 0.71 |
19 | 19 | 0.492 |
2 | 2 | 0.283 |
20 | 20 | 0.127 |
21 | 21 | 0.28 |
22 | 22 | 0.867 |
23 | 23 | 0.209 |
24 | 24 | 0.134 |
25 | 25 | 0.133 |
26 | 26 | 0.128 |
27 | 27 | 0.904 |
28 | 28 | 0.419 |
29 | 29 | 0.00662 |
3 | 3 | 0.124 |
30 | 30 | 0.0712 |
31 | 31 | 0.63 |
32 | 32 | 0.188 |
33 | 33 | 0.275 |
34 | 34 | 0.647 |
35 | 35 | 0.161 |
36 | 36 | 0.0351 |
37 | 37 | 0.236 |
38 | 38 | 0.643 |
39 | 39 | 0.386 |
4 | 4 | 0.615 |
40 | 40 | 0.347 |
41 | 41 | 0.656 |
42 | 42 | 0.083 |
43 | 43 | 0.49 |
44 | 44 | 0.485 |
45 | 45 | 0.355 |
46 | 46 | 0.283 |
47 | 47 | 0.0623 |
48 | 48 | 0.0921 |
49 | 49 | 0.194 |
5 | 5 | 0.864 |
50 | 50 | 0.817 |
51 | 51 | 0.735 |
52 | 52 | 0.606 |
53 | 53 | 0.381 |
54 | 54 | 0.764 |
55 | 55 | 0.208 |
56 | 56 | 0.867 |
57 | 57 | 0.352 |
58 | 58 | 0.128 |
59 | 59 | 0.452 |
6 | 6 | 0.811 |
60 | 60 | 0.672 |
61 | 61 | 0.0914 |
62 | 62 | 0.189 |
63 | 63 | 0.836 |
64 | 64 | 0.428 |
65 | 65 | 0.843 |
66 | 66 | 0.044 |
67 | 67 | 0.854 |
68 | 68 | 0.3 |
69 | 69 | 0.74 |
7 | 7 | 0.127 |
70 | 70 | 0.796 |
71 | 71 | 0.0648 |
72 | 72 | 0.269 |
73 | 73 | 0.978 |
74 | 74 | 0.843 |
75 | 75 | 0.00834 |
76 | 76 | 0.204 |
77 | 77 | 0.419 |
78 | 78 | 0.0993 |
79 | 79 | 0.64 |
8 | 8 | 0.697 |
80 | 80 | 0.249 |
81 | 81 | 0.183 |
82 | 82 | 0.602 |
83 | 83 | 0.953 |
84 | 84 | 0.26 |
85 | 85 | 0.434 |
86 | 86 | 0.115 |
87 | 87 | 0.142 |
88 | 88 | 0.784 |
89 | 89 | 0.556 |
9 | 9 | 0.472 |
90 | 90 | 0.0514 |
91 | 91 | 0.746 |
92 | 92 | 0.994 |
93 | 93 | 0.76 |
94 | 94 | 0.402 |
95 | 95 | 0.039 |
96 | 96 | 0.378 |
97 | 97 | 0.252 |
98 | 98 | 0.398 |
99 | 99 | 0.185 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs10744
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101522 B-lymphocyte cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000945 (lymphocyte of B lineage)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0101522 (B-lymphocyte cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)