FF:10795-110I3: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005574 | ||
| | |DRA_sample_Accession_RNASeq=RNA-Seq@SAMD00005574 | ||
| | |accession_numbers=CAGE;DRX007827;DRR008699;DRZ000124;DRZ001509;DRZ011474;DRZ012859 | ||
| | |accession_numbers_RNASeq=RNA-Seq;DRX057141;DRR062900;DRZ007976 | ||
|ancestors_in_anatomy_facet= | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000084 | |||
|ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:0060058,DOID:14566,DOID:0060083 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100104,FF:0104868 | |||
|comment= | |||
| | |created_by= | ||
| | |creation_date= | ||
| | |data_phase=2 | ||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr6:391743..391759,+!p1@IRF4!2.45!280.83!IRF4;;chr1:212873162..212873188,-!p3@BATF3!2.34!218.86!BATF3;;chr3:111314186..111314204,-!p1@ZBED2!1.80!62.63!ZBED2;;chr1:212873267..212873332,-!p1@BATF3!1.79!81.25!BATF3;;chr7:99621306..99621328,+!p5@ZKSCAN1!1.79!60.65!ZKSCAN1;;chr14:75988771..75988826,+!p1@BATF!1.70!64.93!BATF;;chr1:151798546..151798590,-!p2@RORC!1.68!47.30!RORC;;chr1:212873084..212873137,-!p2@BATF3!1.64!42.85!BATF3;;chr1:25291475..25291511,-!p2@RUNX3!1.62!40.38!RUNX3;;chr1:212873200..212873230,-!p5@BATF3!1.56!35.10!BATF3;;chr2:231090433..231090469,+!p1@SP140!1.50!30.49!SP140;;chr2:231090471..231090504,+!p2@SP140!1.49!30.16!SP140;;chr14:75988831..75988847,+!p2@BATF!1.46!28.02!BATF;;chr19:36204309..36204335,+!p1@ZBTB32!1.46!27.52!ZBTB32;;chr6:135502408..135502459,+!p2@MYB!1.45!31.31!MYB;;chr1:212873061..212873080,-!p4@BATF3!1.45!27.03!BATF3;;chr6:126240442..126240459,+!p4@NCOA7!1.44!33.29!NCOA7;;chr7:50348268..50348366,+!p4@IKZF1!1.44!26.37!IKZF1;;chr20:42295745..42295765,+!p1@MYBL2!1.43!402.12!MYBL2;;chr7:50344289..50344323,+!p1@IKZF1!1.42!25.54!IKZF1;;chr17:8027418..8027432,-!p1@HES7!1.41!24.72!HES7;;chr9:4117869..4117882,-!p12@GLIS3!1.40!24.23!GLIS3;;chr6:135502501..135502546,+!p1@MYB!1.39!28.35!MYB;;chr11:34645791..34645836,+!p3@EHF!1.38!23.24!EHF;;chr19:45260775..45260838,+!p5@BCL3!1.36!28.68!BCL3;;chr6:126240380..126240430,+!p2@NCOA7!1.32!50.76!NCOA7;;chr20:62462566..62462631,-!p1@ZBTB46!1.32!37.41!ZBTB46;;chr6:106534192..106534224,+!p1@PRDM1!1.21!42.85!PRDM1;;chr2:191906489..191906517,-!p6@STAT4!1.20!14.67!STAT4;;chr6:126240463..126240489,+!p6@NCOA7!1.16!15.16!NCOA7;;chr15:60884706..60884743,-!p1@RORA!1.15!67.57!RORA;;chr6:106534230..106534254,+!p2@PRDM1!1.15!32.80!PRDM1;;chr22:30144620..30144638,-!p7@ZMAT5!1.15!13.02!ZMAT5;;chr12:27485762..27485776,+!p3@ARNTL2!1.13!33.46!ARNTL2;;chr20:42295713..42295738,+!p2@MYBL2!1.11!70.37!MYBL2;;chr22:30144465..30144495,-!p6@ZMAT5!1.11!11.87!ZMAT5;;chr1:158979872..158979898,+!p3@IFI16!1.09!35.27!IFI16;;chr6:106546808..106546833,+!p3@PRDM1!1.09!14.34!PRDM1;;chr1:92951607..92951661,-!p1@GFI1!1.09!11.21!GFI1;;chr3:18486354..18486377,-!p2@SATB1!1.07!13.35!SATB1;;chr13:100634031..100634045,+!p1@ZIC2!1.06!10.38!ZIC2;;chr1:25256756..25256774,-!p1@RUNX3!1.04!18.79!RUNX3;;chr3:111314230..111314241,-!p2@ZBED2!1.04!10.05!ZBED2;;chr6:45390399..45390418,+!p15@RUNX2!1.02!9.39!RUNX2;;chr21:47063625..47063658,+!p1@PCBP3!1.01!41.20!PCBP3;;chr9:4300050..4300118,-!p1@GLIS3!1.00!59.82!GLIS3;;chr6:45390300..45390335,+!p4@RUNX2!1.00!14.17!RUNX2;;chr1:203764633..203764674,+!p2@ZC3H11A!0.99!14.34!ZC3H11A;;chr6:135502472..135502489,+!p3@MYB!0.99!8.73!MYB;;chr7:128577972..128578047,+!p1@IRF5!0.98!13.68!IRF5;;chr1:158978768..158978800,+!p8@IFI16!0.98!8.57!IFI16;;chr1:3569072..3569093,+!p1@TP73!0.98!8.57!TP73;;chr14:95236551..95236576,-!p2@GSC!0.98!8.57!GSC;;chr16:85932760..85932775,+!p1@IRF8!0.97!8.24!IRF8;;chr2:97202480..97202499,+!p1@ARID5A!0.94!80.75!ARID5A;;chr7:50344251..50344288,+!p3@IKZF1!0.94!7.75!IKZF1;;chr2:231134598..231134640,+!p6@SP140!0.93!7.42!SP140;;chr6:45390442..45390479,+!p8@RUNX2!0.91!11.21!RUNX2;;chr8:145669791..145669834,-!p1@TONSL!0.90!20.77!TONSL;;chr6:45390025..45390076,+!p2@RUNX2!0.90!17.14!RUNX2;;chr8:28243813..28243839,-!p4@ZNF395!0.90!12.85!ZNF395;;chr16:29818199..29818216,+!p11@MAZ!0.89!11.37!MAZ;;chr2:46524897..46524911,+!p2@EPAS1!0.86!18.29!EPAS1;;chr6:45390343..45390388,+!p10@RUNX2!0.86!8.73!RUNX2;;chr6:100061724..100061753,+!p1@PRDM13!0.86!6.26!PRDM13;;chr6:45390077..45390105,+!p9@RUNX2!0.85!7.91!RUNX2;;chr1:46972279..46972288,+!p1@DMBX1!0.85!6.10!DMBX1;;chrX:152599604..152599626,+!p1@ZNF275!0.84!48.12!ZNF275;;chr11:614891..614902,-!p15@IRF7!0.84!5.93!IRF7;;chr19:50432453..50432468,+!p1@ATF5!0.83!342.79!ATF5;;chr8:116681409..116681431,-!p2@TRPS1!0.83!16.48!TRPS1;;chr9:77112244..77112262,+!p1@RORB!0.82!6.43!RORB;;chr3:27763807..27763822,-!p1@EOMES!0.82!5.60!EOMES;;chr1:151804244..151804310,-!p1@RORC!0.81!5.44!RORC;;chr5:138609782..138609826,+!p5@MATR3!0.80!37.08!MATR3;;chr13:27998854..27998866,+!p3@GTF3A!0.80!11.37!GTF3A;;chr19:31840130..31840160,-!p2@TSHZ3!0.80!8.57!TSHZ3;;chr5:176738887..176738934,-!p1@MXD3!0.79!37.58!MXD3;;chr11:6947720..6947812,+!p1@ZNF215!0.79!6.92!ZNF215;;chrY:21906594..21906622,-!p1@KDM5D!0.79!5.11!KDM5D;;chr11:615570..615721,-!p2@IRF7!0.78!10.38!IRF7;;chr11:120107344..120107351,+!p1@POU2F3!0.78!6.26!POU2F3;;chr13:100623375..100623425,-!p1@ZIC5!0.77!4.94!ZIC5;;chr21:36207322..36207331,-!p65@RUNX1!0.77!4.94!RUNX1;;chr19:57791328..57791377,+!p2@ZNF460!0.76!62.96!ZNF460;;chr12:27485785..27485816,+!p1@ARNTL2!0.76!36.75!ARNTL2;;chr13:27998831..27998851,+!p2@GTF3A!0.76!31.48!GTF3A;;chr1:221052776..221052799,+!p1@HLX!0.76!9.06!HLX;;chr1:151798601..151798617,-!p3@RORC!0.76!4.78!RORC;;chrY:2803415..2803468,+!p1@ZFY!0.76!4.78!ZFY;;chr19:12902289..12902307,+!p1@JUNB!0.75!1172.58!JUNB;;chr2:8822176..8822196,+!p1@ID2!0.75!728.76!ID2;;chr1:151319654..151319698,-!p2@RFX5!0.75!10.88!RFX5;;chr8:28243785..28243799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| |||
|ffid_belonging_in_development=CL:0000134,CL:0000051 | |||
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| | |||
|fonse_cell_line=FF:0100104 | |fonse_cell_line=FF:0100104 | ||
|fonse_cell_line_closure=FF:0100104 | |fonse_cell_line_closure=FF:0100104 | ||
Line 66: | Line 42: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=CL:0000084;;EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/anaplastic%2520large%2520cell%2520lymphoma%2520cell%2520line%253aKi-JK.CNhs11881.10795-110I3.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/anaplastic%2520large%2520cell%2520lymphoma%2520cell%2520line%253aKi-JK.CNhs11881.10795-110I3.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/anaplastic%2520large%2520cell%2520lymphoma%2520cell%2520line%253aKi-JK.CNhs11881.10795-110I3.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/anaplastic%2520large%2520cell%2520lymphoma%2520cell%2520line%253aKi-JK.CNhs11881.10795-110I3.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/anaplastic%2520large%2520cell%2520lymphoma%2520cell%2520line%253aKi-JK.CNhs11881.10795-110I3.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10795-110I3 | |||
|is_a=CL:0000084;;EFO:0002091;;FF:0000210;;FF:0104868 | |||
|is_obsolete= | |||
|library_id=CNhs11881 | |||
|library_id_phase_based=2:CNhs11881 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10795 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10795 | |||
|name=anaplastic large cell lymphoma cell line:Ki-JK | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11881,LSID830,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.059584765244611,0.0662528064680222,-0.0549305028750934,0.17244043060059,0,0,0,0.0662528064680222,0,0,0,0,0,0,0,0.0662528064680222,0,0.295822422954285,0,0,0,0,0,0.551462776666412,0,0,0.200213921660344,0,0,0,0,0,0,0,0,0,0,0,0,0.0986888536589954,0.094451768325009,0,0,0,0,0,0,0,0.00891138212117675,0,0,0,0.889691487180119,0,-0.0041341736802575,0.0662528064680222,0.352153072060107,0,0,-0.097343627213097,0,0,0,0,0,0,0,0.0662528064680222,0,0,0.123723537352191,0,0,0.0662528064680222,0,0,0,0,0,0,0,0,0,0,-0.552571649267773,0,0,0,0.0296908585169707,0.31692417536178,0,0,0.324710336467235,0,0.0256881861144843,0.147957284526556,0,0,0,0,0,0,0.123723537352191,0,0,0,0,0,0,0,0,0,0,0.0135778037430376,0.174470236593647,0,0,-0.0204656464687731,-0.151665704273657,0,0,0.174470236593647,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0,0.0256881861144843,0,0,0,0,0,0,0,0,0,0,0,-0.247178875285564,0,-0.254183423421011,0.0763876528075252,0.0662528064680222,0,-0.146915676573139,0,0,0,0,0,0,0,0,0,-0.128119866952565,0,0.124057685004332,0,0.0662528064680222,0,0,0.0131905323372484,-0.239219424430385,0,0.0372041062414874,0.106125975516279,0,0,0,0,0.090823171839195,0,0.00284405355845009,-0.0827201683234173,-0.221611588102807,-0.959835602840941,0.0528206813894012,0,0,0,-0.429992374072861,0.484298393027867,0,0,-0.121779851751874,-0.181349618560659,0,0,-0.391044581551635,0,-0.0604546749983877,-0.244355945962918,0,0.388533652801597,0,0,0,0,0,0.0662528064680222,0,0,0,0,0,-0.0574934668214365,0.17027983004514,0.0662528064680222,0,0,0,-0.393480471032138,0,-0.0138323107379372,-0.373286155956567,-0.0951617398912134,-0.113734128806291,-0.229125843427514,0,-0.302389727009913,-0.133929148534349,-0.284968724421038,0.0296908585169707,-0.147401849371139,-0.189981719549847,0,0.0327535369413348,-0.611802392520364,-0.0163962046198144,0.143875146330963,-0.0197297988941045,0.28455996590243,0.22706542693912,0,0,-0.0188359114117362,-0.370125989523294,0,-0.0095579864261901,-0.423861908008751,-0.0456249680751969,-0.637861033241699,-0.621767192965395,-0.120683732725993,0.0124712807327603,-0.0395325284566706,-0.282966216302947,-0.0317815305628377,-0.0345286785511948,0,0,-0.0150079309417894,-0.0592930838893391,-0.136491434172853,0.597073843641563,0.00133101117528528,-0.483977461810981,-0.0683442610773682,0,-0.470133602030494,0.2104287450258,0,0,0.00119671208156447,0,0,0.0149512604525066,0,0,-0.00605450058656198,-0.365021906436519,0.162162236158591,0,-0.066721943241588,0,-0.130700824632983,0,-0.0351580948477633,0,0,-0.0644078180293647,0,0.157889547011476,0.261203420459202,-0.146170475607293,0.63384835072356,0.0652767105403655,0.159219553404388,0.100405926800037,-0.310025154851697,0.574365916930402,-0.0580548901253913,-0.0881268324752877,0,-0.58494856315845,-0.679498131621524,-0.00623789510538275,-0.583529904229572,0,-0.513772859078872,0,0.0690800286637816,0,-0.0824407235190596,-0.145415953759105,0.14068456837229,0.361971359080552,0,0.158190145116653,-0.788130937773974,0,-0.097914136578333,-0.0836316105612801,0,-0.150367083334639,-0.697695966512583,0.0248827841121995,-0.00847473356132805,0,0.00744524875815433,0,0,-0.139583758981822,0.097694473674817,0,-0.216685498284361,-0.348173467977663,0.0452046317391744,0.0584991631587133,0,0,0.0493689992265615,0,0,-0.60592806381803,-0.110237758519494,0.116589638450781,-0.187073535018734,-0.0489755168342357,-0.108622809454255,0,0,-0.111274959497154,0,0.0567503830899055,0,0.123723537352191,-0.0674567996848476,0,0,0,0,0,0,0,0,0,0,0,0,0.464576618814496,0.0103608437907649,0,0.0819491651703075,0,0,0,0,0,0,0,0,-0.435505758535935,-0.174255331009904,0.0968853796545768,0,0,0,0,0.0453060436822585,0.129933949344482,0,0.201307804941574,0,0.497804638447502,0,0,0.0375825475629794,0,0,0.0331264032340111,0.0872351182968235,0.00852234941435816,-0.0523791408446891,0,0,0,0.172191031700922,0,0,0,0,0.0623946076628163,0,0,-0.112462591588325,0,0.116702870536941,0.217014307813089,0,0.353564093076078,-0.0305929436809333,-0.147835684928931,0,0,1.32310259638444,0,0,-0.0261104230916998,0,0.123723537352191,0,0,0,0,0,0,0.649420672934469,-0.148061705931733,0,0,0,0,0,0,0,0,0,0,0,-0.231815453255998,0.082246179935137,0,0,0,0,0,0,0,-0.0241060230789031,0.139914489297451,0,0,0.0331264032340111,0,0.0662528064680222,0,0,0,0.620995272649962,0,0,0.0662528064680222,0,0,0.352153072060107,0,0,0,0,0.221157323848989,0,0,0.0878320418136989,0,0,0,0,0,0,0.00648156106057686,0,0,0,0,0,0,0.000404451316742993,-0.352996147536023,0,0,0,0,0,0.0662528064680222,0,-0.0549305028750934,0,0.123723537352191,0,0,0.219286137730229,0,0,0,0.156233061446577,0,0.059584765244611,0,0.0662528064680222,0,0,0,0.123723537352191,0.0331264032340111,0.0662528064680222,0,0,0,0,0,0,0,0,0,0.0618617686760955,0,0,0,-0.272096311817289,0,-0.28720751597291,0,0,0,-0.232628352633041,0,0,0,0,0,0,0.00178597920548402,0,0,0,0,0,0,0,0.0662528064680222,0,0,0,0,0,0,0,0,0,0,0.174470236593647,0,0,0.0662528064680222,0,0,0,0.0528709156829159,0,0,0,0,0,0,0,0.551462776666412,0,0.875390228171296,-0.0920328098005262,0,0,0.0119234838651102,0,0,0,-0.121391584937107,-0.250093996589137,-0.0820265641804895,0,0,0,-0.054385572482455,0.889691487180119,0,0,0.0662528064680222,-0.000524580950879178,0,0,0,0,0,0,0,0.0331264032340111,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.295822422954285,0,0,0,0,0,0,0,0,0,0,0,0.0331264032340111,0,0,0,0,0,0,0,0,0,0,0,0,0,0.261029446235733,0,0,0.0949881719101066,0,0,0,0,0,0,0.0322414431926057,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0331264032340111,0.0331264032340111,0,0,0,0.0662528064680222,0.094451768325009,0,0,0,0.0479432165786895,0,0,0,0,0,0,0.261029446235733,0,0.0662528064680222,0,0,0,0.0331264032340111,0,0,0,0,0,0,0,0.123723537352191,0,0,0,0,0,0,0,0,0,0,0,0.174470236593647,0,0,0,0.0662528064680222,0,0,0,-0.0722583555111888,0,0,0,0,0,0,0,0,0,0,0,0,0,0.250374112120876,0,0.09009360436362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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=0.8742 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.66 | |||
|rna_od260/280=2.11 | |||
|rna_position=I3 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=110I3 | |||
|rna_weight_ug=23.6034 | |||
|rnaseq_library_id=RDhi10084 | |||
|sample_age=15 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb1065 | |||
|sample_cell_line=Ki-JK | |||
|sample_cell_lot= | |||
|sample_cell_type=lymphoid cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=anaplastic large cell lymphoma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.21449982152058e-226!GO:0043227;membrane-bound organelle;8.45457075017318e-184!GO:0043231;intracellular membrane-bound organelle;2.01331028641552e-183!GO:0043226;organelle;5.11536443058564e-182!GO:0043229;intracellular organelle;9.38711820144002e-182!GO:0005737;cytoplasm;9.21440569034083e-175!GO:0044422;organelle part;1.22608158823979e-170!GO:0044446;intracellular organelle part;3.81375100488166e-169!GO:0032991;macromolecular complex;1.4741345816251e-133!GO:0044444;cytoplasmic part;2.19166177785015e-124!GO:0030529;ribonucleoprotein complex;4.11039432545972e-107!GO:0044428;nuclear part;1.92945371818544e-99!GO:0003723;RNA binding;1.27143372033359e-93!GO:0043233;organelle lumen;2.55136819284557e-91!GO:0031974;membrane-enclosed lumen;2.55136819284557e-91!GO:0044237;cellular metabolic process;1.00167133520859e-90!GO:0044238;primary metabolic process;1.89493844793154e-85!GO:0005739;mitochondrion;5.61074608778876e-81!GO:0043170;macromolecule metabolic process;4.61541092243857e-80!GO:0005634;nucleus;5.72351224140724e-75!GO:0043234;protein complex;8.57272626346936e-69!GO:0006412;translation;2.14480719775048e-68!GO:0006396;RNA processing;2.45347190151105e-65!GO:0005515;protein binding;4.72470431670681e-65!GO:0005840;ribosome;1.84864628946553e-61!GO:0019538;protein metabolic process;5.84218471600803e-59!GO:0031981;nuclear lumen;7.05422141353464e-57!GO:0044260;cellular macromolecule metabolic process;1.55967950580379e-55!GO:0044267;cellular protein metabolic process;4.25102269126433e-55!GO:0044429;mitochondrial part;2.6143914638921e-54!GO:0003735;structural constituent of ribosome;3.05500049445235e-54!GO:0044249;cellular biosynthetic process;3.36643252807251e-53!GO:0031967;organelle envelope;3.09842037172014e-52!GO:0031975;envelope;7.63022506401195e-52!GO:0009059;macromolecule biosynthetic process;6.13863893480748e-51!GO:0016071;mRNA metabolic process;8.65293418137812e-51!GO:0009058;biosynthetic process;3.72435311540352e-50!GO:0031090;organelle membrane;5.489818339536e-49!GO:0033279;ribosomal subunit;2.41827119535306e-47!GO:0008380;RNA splicing;2.62747615331455e-44!GO:0006259;DNA metabolic process;3.71012258217732e-44!GO:0015031;protein transport;4.50010299405378e-44!GO:0033036;macromolecule localization;4.96262072794808e-44!GO:0006397;mRNA processing;2.39816256318096e-43!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.54690835147471e-42!GO:0016043;cellular component organization and biogenesis;5.99504954000642e-42!GO:0005829;cytosol;1.00334021213448e-41!GO:0045184;establishment of protein localization;6.30720165068913e-41!GO:0043283;biopolymer metabolic process;9.90863418632838e-41!GO:0008104;protein localization;7.01775976106038e-40!GO:0043228;non-membrane-bound organelle;7.29933450599845e-40!GO:0043232;intracellular non-membrane-bound organelle;7.29933450599845e-40!GO:0046907;intracellular transport;2.97921175036545e-39!GO:0000166;nucleotide binding;2.1015672556806e-37!GO:0006996;organelle organization and biogenesis;2.85608465618466e-37!GO:0006886;intracellular protein transport;4.63946967476224e-35!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.11087490624876e-35!GO:0005654;nucleoplasm;4.55551071937898e-34!GO:0065003;macromolecular complex assembly;7.70522434276603e-34!GO:0005740;mitochondrial envelope;1.21780889886509e-33!GO:0007049;cell cycle;2.01449137915367e-33!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.17427558861574e-33!GO:0010467;gene expression;6.94903391668514e-32!GO:0019866;organelle inner membrane;7.21560892879231e-32!GO:0005681;spliceosome;1.2901509311192e-31!GO:0031966;mitochondrial membrane;1.64774196164435e-31!GO:0006974;response to DNA damage stimulus;8.6327394748491e-30!GO:0022607;cellular component assembly;4.92848670771091e-29!GO:0044445;cytosolic part;5.08822490540354e-29!GO:0005743;mitochondrial inner membrane;8.07781172311164e-29!GO:0005694;chromosome;2.82858624999453e-28!GO:0022402;cell cycle process;4.66727533446778e-28!GO:0051649;establishment of cellular localization;7.86014384202623e-27!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.17125253821159e-26!GO:0016462;pyrophosphatase activity;1.22148413706016e-26!GO:0016817;hydrolase activity, acting on acid anhydrides;1.63301188684072e-26!GO:0032553;ribonucleotide binding;1.71463057819132e-26!GO:0032555;purine ribonucleotide binding;1.71463057819132e-26!GO:0017076;purine nucleotide binding;2.95481719736322e-26!GO:0051641;cellular localization;3.36400082533215e-26!GO:0017111;nucleoside-triphosphatase activity;3.71980596048336e-26!GO:0044451;nucleoplasm part;4.7986831925788e-26!GO:0005730;nucleolus;5.66926503161049e-26!GO:0000278;mitotic cell cycle;6.45011172903199e-26!GO:0005524;ATP binding;2.22830540324087e-25!GO:0015934;large ribosomal subunit;2.57142881032553e-25!GO:0006281;DNA repair;4.84358548180063e-25!GO:0032559;adenyl ribonucleotide binding;5.09874817670638e-25!GO:0044427;chromosomal part;1.06722661374638e-24!GO:0030554;adenyl nucleotide binding;1.65042271577134e-24!GO:0006119;oxidative phosphorylation;1.69682742005483e-24!GO:0044455;mitochondrial membrane part;2.21422706666778e-24!GO:0031980;mitochondrial lumen;2.36232867294483e-24!GO:0005759;mitochondrial matrix;2.36232867294483e-24!GO:0022403;cell cycle phase;2.48253292845505e-23!GO:0022618;protein-RNA complex assembly;2.86844364476475e-23!GO:0015935;small ribosomal subunit;3.08535945796926e-23!GO:0016874;ligase activity;5.03171863192368e-22!GO:0012505;endomembrane system;5.21418625812517e-22!GO:0006512;ubiquitin cycle;5.21429531772273e-22!GO:0044265;cellular macromolecule catabolic process;9.82861936554982e-22!GO:0000087;M phase of mitotic cell cycle;1.32879209106616e-21!GO:0007067;mitosis;2.52324979892168e-21!GO:0006457;protein folding;6.58968539165267e-21!GO:0003676;nucleic acid binding;1.43708331267999e-20!GO:0051276;chromosome organization and biogenesis;2.46036159827892e-20!GO:0009719;response to endogenous stimulus;3.69613538059038e-20!GO:0005746;mitochondrial respiratory chain;5.42109347050863e-20!GO:0016887;ATPase activity;6.3981180788164e-20!GO:0000279;M phase;1.5956557343898e-19!GO:0042254;ribosome biogenesis and assembly;2.35607534892416e-19!GO:0006260;DNA replication;3.34347598758075e-19!GO:0005635;nuclear envelope;6.08425415855746e-19!GO:0006605;protein targeting;1.69554927294389e-18!GO:0009057;macromolecule catabolic process;2.95886108670955e-18!GO:0043285;biopolymer catabolic process;3.23339058457372e-18!GO:0000502;proteasome complex (sensu Eukaryota);4.45905692238087e-18!GO:0042623;ATPase activity, coupled;5.17896860941897e-18!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.8058363926222e-18!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);7.65695224965957e-18!GO:0050136;NADH dehydrogenase (quinone) activity;7.76058499123406e-18!GO:0003954;NADH dehydrogenase activity;7.76058499123406e-18!GO:0008137;NADH dehydrogenase (ubiquinone) activity;7.76058499123406e-18!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.45988254794949e-17!GO:0044248;cellular catabolic process;1.80327198733777e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;1.88556848338342e-17!GO:0051301;cell division;2.11529513916112e-17!GO:0019941;modification-dependent protein catabolic process;2.11529513916112e-17!GO:0043632;modification-dependent macromolecule catabolic process;2.11529513916112e-17!GO:0012501;programmed cell death;2.35698884895621e-17!GO:0044453;nuclear membrane part;2.79731705353768e-17!GO:0008135;translation factor activity, nucleic acid binding;3.08224867990731e-17!GO:0044257;cellular protein catabolic process;3.09623977295976e-17!GO:0043412;biopolymer modification;3.15807648373473e-17!GO:0006511;ubiquitin-dependent protein catabolic process;4.27561838822749e-17!GO:0005761;mitochondrial ribosome;4.37126864137112e-17!GO:0000313;organellar ribosome;4.37126864137112e-17!GO:0006915;apoptosis;5.88177975188731e-17!GO:0006913;nucleocytoplasmic transport;1.09329211534486e-16!GO:0044432;endoplasmic reticulum part;1.20956139166924e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;1.68461449549561e-16!GO:0000375;RNA splicing, via transesterification reactions;1.68461449549561e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.68461449549561e-16!GO:0031965;nuclear membrane;2.78607777293055e-16!GO:0008219;cell death;2.99454845757469e-16!GO:0016265;death;2.99454845757469e-16!GO:0051169;nuclear transport;3.24814690887978e-16!GO:0042775;organelle ATP synthesis coupled electron transport;3.92946355258631e-16!GO:0042773;ATP synthesis coupled electron transport;3.92946355258631e-16!GO:0030964;NADH dehydrogenase complex (quinone);8.87828288262509e-16!GO:0045271;respiratory chain complex I;8.87828288262509e-16!GO:0005747;mitochondrial respiratory chain complex I;8.87828288262509e-16!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.06583214243004e-15!GO:0006325;establishment and/or maintenance of chromatin architecture;3.69336026355674e-15!GO:0051082;unfolded protein binding;4.51184134586115e-15!GO:0005783;endoplasmic reticulum;6.51067187965731e-15!GO:0006413;translational initiation;7.63355332394509e-15!GO:0006464;protein modification process;8.20880627484668e-15!GO:0006323;DNA packaging;1.23406797040976e-14!GO:0006399;tRNA metabolic process;1.49064799429643e-14!GO:0005643;nuclear pore;1.76840473701175e-14!GO:0003743;translation initiation factor activity;6.61075147231214e-14!GO:0048770;pigment granule;6.81909873236629e-14!GO:0042470;melanosome;6.81909873236629e-14!GO:0030163;protein catabolic process;8.10881571961522e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;8.30937720119859e-14!GO:0004386;helicase activity;8.45277463625908e-14!GO:0051186;cofactor metabolic process;8.76596383579469e-14!GO:0008134;transcription factor binding;9.70433951655739e-14!GO:0050657;nucleic acid transport;1.01596929042067e-13!GO:0051236;establishment of RNA localization;1.01596929042067e-13!GO:0050658;RNA transport;1.01596929042067e-13!GO:0006364;rRNA processing;1.49973905857951e-13!GO:0006403;RNA localization;1.51925282729777e-13!GO:0016072;rRNA metabolic process;1.96074701263557e-13!GO:0043687;post-translational protein modification;1.99918722287153e-13!GO:0017038;protein import;2.37522345936078e-13!GO:0016604;nuclear body;2.68863947963511e-13!GO:0051726;regulation of cell cycle;2.91835736398119e-13!GO:0000074;regulation of progression through cell cycle;3.92165470622992e-13!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.31965234657914e-13!GO:0065002;intracellular protein transport across a membrane;6.98212092935049e-13!GO:0000785;chromatin;7.8004710939026e-13!GO:0046930;pore complex;9.93193417265385e-13!GO:0006446;regulation of translational initiation;1.01370802333235e-12!GO:0005789;endoplasmic reticulum membrane;1.26076694575726e-12!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.04015257759986e-12!GO:0008026;ATP-dependent helicase activity;2.11126814852266e-12!GO:0065004;protein-DNA complex assembly;7.25222497511131e-12!GO:0042981;regulation of apoptosis;8.37558377367061e-12!GO:0051028;mRNA transport;9.50606560901568e-12!GO:0016740;transferase activity;9.69154345040793e-12!GO:0043067;regulation of programmed cell death;1.06393085751612e-11!GO:0016779;nucleotidyltransferase activity;2.42769695153531e-11!GO:0009055;electron carrier activity;3.06075847415715e-11!GO:0006333;chromatin assembly or disassembly;3.17103209740423e-11!GO:0009259;ribonucleotide metabolic process;3.2462989401795e-11!GO:0006163;purine nucleotide metabolic process;3.45207986526637e-11!GO:0016787;hydrolase activity;3.99569875195431e-11!GO:0006732;coenzyme metabolic process;5.03631115852908e-11!GO:0006164;purine nucleotide biosynthetic process;8.55903689960156e-11!GO:0051246;regulation of protein metabolic process;1.28874406811646e-10!GO:0009260;ribonucleotide biosynthetic process;1.58671415244877e-10!GO:0043566;structure-specific DNA binding;1.59678554326331e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.66620986594459e-10!GO:0000775;chromosome, pericentric region;2.35414887737118e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.35414887737118e-10!GO:0004812;aminoacyl-tRNA ligase activity;2.35414887737118e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.35414887737118e-10!GO:0048193;Golgi vesicle transport;3.32670250431687e-10!GO:0016568;chromatin modification;3.79940689872538e-10!GO:0006261;DNA-dependent DNA replication;4.01839212695532e-10!GO:0016607;nuclear speck;4.13497928573259e-10!GO:0009150;purine ribonucleotide metabolic process;4.24733927960951e-10!GO:0030532;small nuclear ribonucleoprotein complex;5.03684751886728e-10!GO:0043038;amino acid activation;6.37405224946191e-10!GO:0006418;tRNA aminoacylation for protein translation;6.37405224946191e-10!GO:0043039;tRNA aminoacylation;6.37405224946191e-10!GO:0051170;nuclear import;6.37405224946191e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;7.49126797948488e-10!GO:0008565;protein transporter activity;9.64447265589163e-10!GO:0009152;purine ribonucleotide biosynthetic process;1.06158499044668e-09!GO:0009056;catabolic process;1.17858634077244e-09!GO:0003697;single-stranded DNA binding;1.34261587944862e-09!GO:0051188;cofactor biosynthetic process;2.12798669235829e-09!GO:0006606;protein import into nucleus;2.24778571465797e-09!GO:0016070;RNA metabolic process;2.31629531914563e-09!GO:0007005;mitochondrion organization and biogenesis;2.45357164162372e-09!GO:0005794;Golgi apparatus;2.59242557827575e-09!GO:0008639;small protein conjugating enzyme activity;2.84683708331088e-09!GO:0043069;negative regulation of programmed cell death;3.23678582709731e-09!GO:0043066;negative regulation of apoptosis;4.2850164021629e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.61108573590158e-09!GO:0015078;hydrogen ion transmembrane transporter activity;4.67523768368187e-09!GO:0009142;nucleoside triphosphate biosynthetic process;5.32190611848625e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;5.32190611848625e-09!GO:0009141;nucleoside triphosphate metabolic process;5.32190611848625e-09!GO:0009199;ribonucleoside triphosphate metabolic process;5.38134920135658e-09!GO:0004842;ubiquitin-protein ligase activity;9.16975457018026e-09!GO:0003899;DNA-directed RNA polymerase activity;1.01628830079257e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.01702840918642e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.01702840918642e-08!GO:0019829;cation-transporting ATPase activity;1.01702840918642e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.01885069934703e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.01885069934703e-08!GO:0006334;nucleosome assembly;1.20693507619683e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.24423585616265e-08!GO:0019787;small conjugating protein ligase activity;1.66648515255883e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;1.75972338827382e-08!GO:0006916;anti-apoptosis;2.54252179487673e-08!GO:0006793;phosphorus metabolic process;2.64367135643234e-08!GO:0006796;phosphate metabolic process;2.64367135643234e-08!GO:0031497;chromatin assembly;3.1052607419853e-08!GO:0003712;transcription cofactor activity;3.22504820065096e-08!GO:0005839;proteasome core complex (sensu Eukaryota);3.86874641120698e-08!GO:0009108;coenzyme biosynthetic process;4.97440672905783e-08!GO:0006366;transcription from RNA polymerase II promoter;5.40943439897093e-08!GO:0015986;ATP synthesis coupled proton transport;5.82350655680851e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;5.82350655680851e-08!GO:0015630;microtubule cytoskeleton;8.62934084937942e-08!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.20826197148684e-07!GO:0016881;acid-amino acid ligase activity;1.34363801952977e-07!GO:0009060;aerobic respiration;1.4329092021879e-07!GO:0000245;spliceosome assembly;1.96695163726786e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.00220147013721e-07!GO:0051325;interphase;2.07032679164587e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.11006664055759e-07!GO:0004298;threonine endopeptidase activity;2.1215066261515e-07!GO:0051329;interphase of mitotic cell cycle;2.50798014110958e-07!GO:0006754;ATP biosynthetic process;3.08646181752318e-07!GO:0006753;nucleoside phosphate metabolic process;3.08646181752318e-07!GO:0046034;ATP metabolic process;3.39915333664715e-07!GO:0016310;phosphorylation;3.44268069487925e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.91335819496707e-07!GO:0006461;protein complex assembly;4.03117397921546e-07!GO:0005819;spindle;4.09620240097677e-07!GO:0006752;group transfer coenzyme metabolic process;4.26912434277244e-07!GO:0045259;proton-transporting ATP synthase complex;4.46154250265787e-07!GO:0005657;replication fork;4.55640890368262e-07!GO:0045333;cellular respiration;4.99697043082795e-07!GO:0009117;nucleotide metabolic process;5.9599139229646e-07!GO:0005667;transcription factor complex;6.87098506699775e-07!GO:0006888;ER to Golgi vesicle-mediated transport;8.24091173071858e-07!GO:0005762;mitochondrial large ribosomal subunit;8.60992170758436e-07!GO:0000315;organellar large ribosomal subunit;8.60992170758436e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;9.08573583545227e-07!GO:0005793;ER-Golgi intermediate compartment;9.43357027689661e-07!GO:0016192;vesicle-mediated transport;1.1678202447892e-06!GO:0005813;centrosome;1.41118341363224e-06!GO:0003724;RNA helicase activity;1.81976382162079e-06!GO:0005815;microtubule organizing center;1.86587718921968e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;2.04477414662603e-06!GO:0032446;protein modification by small protein conjugation;2.51351724891782e-06!GO:0051168;nuclear export;2.89332141477463e-06!GO:0008094;DNA-dependent ATPase activity;3.10493839438937e-06!GO:0016567;protein ubiquitination;4.02576376705038e-06!GO:0016741;transferase activity, transferring one-carbon groups;5.13631103166032e-06!GO:0000075;cell cycle checkpoint;6.55590355092392e-06!GO:0007051;spindle organization and biogenesis;7.19711965924579e-06!GO:0030880;RNA polymerase complex;7.68424704279025e-06!GO:0044452;nucleolar part;7.91890661955836e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.91890661955836e-06!GO:0006417;regulation of translation;9.16811968028492e-06!GO:0008033;tRNA processing;9.43047453143225e-06!GO:0006414;translational elongation;9.57330959371113e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.03242326900813e-05!GO:0015399;primary active transmembrane transporter activity;1.03242326900813e-05!GO:0003690;double-stranded DNA binding;1.03333624366542e-05!GO:0008168;methyltransferase activity;1.23866293931134e-05!GO:0007059;chromosome segregation;1.44187629069636e-05!GO:0007243;protein kinase cascade;1.44331623975394e-05!GO:0006302;double-strand break repair;1.47466867961179e-05!GO:0003684;damaged DNA binding;1.49771414101298e-05!GO:0006401;RNA catabolic process;1.75499945264118e-05!GO:0000151;ubiquitin ligase complex;1.84490467297795e-05!GO:0030120;vesicle coat;1.86265748803306e-05!GO:0030662;coated vesicle membrane;1.86265748803306e-05!GO:0000786;nucleosome;1.89371998508473e-05!GO:0006613;cotranslational protein targeting to membrane;1.94117875913421e-05!GO:0004518;nuclease activity;1.94117875913421e-05!GO:0055029;nuclear DNA-directed RNA polymerase complex;2.07919375705499e-05!GO:0000428;DNA-directed RNA polymerase complex;2.07919375705499e-05!GO:0006099;tricarboxylic acid cycle;2.18060173442635e-05!GO:0046356;acetyl-CoA catabolic process;2.18060173442635e-05!GO:0016491;oxidoreductase activity;2.44739403486821e-05!GO:0048475;coated membrane;2.52497676761771e-05!GO:0030117;membrane coat;2.52497676761771e-05!GO:0004527;exonuclease activity;2.70254826983564e-05!GO:0005788;endoplasmic reticulum lumen;2.94115257336264e-05!GO:0043021;ribonucleoprotein binding;3.13828447008985e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;3.42871464349477e-05!GO:0048523;negative regulation of cellular process;3.43292546419308e-05!GO:0031326;regulation of cellular biosynthetic process;3.71552867958209e-05!GO:0016853;isomerase activity;3.89816886718553e-05!GO:0003729;mRNA binding;3.92346451462586e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.20432297853539e-05!GO:0006383;transcription from RNA polymerase III promoter;5.48267341932095e-05!GO:0000776;kinetochore;6.87536512578879e-05!GO:0007088;regulation of mitosis;7.20435337248018e-05!GO:0006091;generation of precursor metabolites and energy;7.22287502626325e-05!GO:0006402;mRNA catabolic process;7.37378875908573e-05!GO:0003924;GTPase activity;7.37378875908573e-05!GO:0009165;nucleotide biosynthetic process;7.58912784440336e-05!GO:0006084;acetyl-CoA metabolic process;8.51223198548582e-05!GO:0043681;protein import into mitochondrion;8.59536423547848e-05!GO:0045786;negative regulation of progression through cell cycle;8.72726401247543e-05!GO:0009889;regulation of biosynthetic process;8.92989641755883e-05!GO:0006612;protein targeting to membrane;9.23736444100309e-05!GO:0043623;cellular protein complex assembly;9.63604139712147e-05!GO:0008186;RNA-dependent ATPase activity;9.70010703652679e-05!GO:0006310;DNA recombination;9.83733785759298e-05!GO:0003682;chromatin binding;0.000103027155944391!GO:0009109;coenzyme catabolic process;0.000124574838548891!GO:0051187;cofactor catabolic process;0.000134540144126285!GO:0000314;organellar small ribosomal subunit;0.000136729381398599!GO:0005763;mitochondrial small ribosomal subunit;0.000136729381398599!GO:0045454;cell redox homeostasis;0.00013810228339203!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000147234184298871!GO:0043492;ATPase activity, coupled to movement of substances;0.000148084741873373!GO:0006950;response to stress;0.000155184420296818!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000161581188410569!GO:0003713;transcription coactivator activity;0.000168181680161326!GO:0006626;protein targeting to mitochondrion;0.000171460581976715!GO:0006352;transcription initiation;0.00017168519222584!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000172070123806294!GO:0006839;mitochondrial transport;0.000178881534886399!GO:0005768;endosome;0.000189505614483475!GO:0032508;DNA duplex unwinding;0.000220122239902397!GO:0032392;DNA geometric change;0.000220122239902397!GO:0043284;biopolymer biosynthetic process;0.000223178162792347!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000224582803231601!GO:0006818;hydrogen transport;0.000224759495516076!GO:0042770;DNA damage response, signal transduction;0.000225345215336509!GO:0015992;proton transport;0.000230596980433894!GO:0022890;inorganic cation transmembrane transporter activity;0.000258169904440518!GO:0000059;protein import into nucleus, docking;0.000260997572011197!GO:0031324;negative regulation of cellular metabolic process;0.000261310347514905!GO:0048519;negative regulation of biological process;0.000265930714660684!GO:0019867;outer membrane;0.000275480627551591!GO:0008654;phospholipid biosynthetic process;0.000277386267743067!GO:0031072;heat shock protein binding;0.000279860250239799!GO:0065009;regulation of a molecular function;0.000296859628008892!GO:0004004;ATP-dependent RNA helicase activity;0.000298143271322149!GO:0008632;apoptotic program;0.000304566389341411!GO:0031968;organelle outer membrane;0.000310089317829991!GO:0043065;positive regulation of apoptosis;0.000325060807343254!GO:0005525;GTP binding;0.000331671302940749!GO:0003678;DNA helicase activity;0.000346589874868539!GO:0000049;tRNA binding;0.000351628089266707!GO:0043068;positive regulation of programmed cell death;0.000363979424127871!GO:0005637;nuclear inner membrane;0.000368224784395249!GO:0006520;amino acid metabolic process;0.000368224784395249!GO:0005770;late endosome;0.000382974129966646!GO:0051052;regulation of DNA metabolic process;0.000383555771838115!GO:0019752;carboxylic acid metabolic process;0.000412038533195627!GO:0051427;hormone receptor binding;0.000412331991682863!GO:0030867;rough endoplasmic reticulum membrane;0.000436391082070894!GO:0000228;nuclear chromosome;0.000440576472903023!GO:0005885;Arp2/3 protein complex;0.000456354358474063!GO:0006082;organic acid metabolic process;0.000458635964914511!GO:0000082;G1/S transition of mitotic cell cycle;0.000476562524589886!GO:0004674;protein serine/threonine kinase activity;0.000506645377375375!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000545183224541277!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000548592085883111!GO:0006268;DNA unwinding during replication;0.000570303728427332!GO:0005773;vacuole;0.000582979098567754!GO:0016563;transcription activator activity;0.000612762993635338!GO:0006611;protein export from nucleus;0.000634765058760534!GO:0000323;lytic vacuole;0.00064823150887178!GO:0005764;lysosome;0.00064823150887178!GO:0042802;identical protein binding;0.00065279254729906!GO:0016859;cis-trans isomerase activity;0.000655647220816716!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000688343468697342!GO:0005684;U2-dependent spliceosome;0.000694010802371459!GO:0006405;RNA export from nucleus;0.00070892443842143!GO:0046489;phosphoinositide biosynthetic process;0.000714820610455043!GO:0005741;mitochondrial outer membrane;0.000766626453901147!GO:0035257;nuclear hormone receptor binding;0.00077751774551538!GO:0019843;rRNA binding;0.000866592631414371!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000867966596374637!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000867966596374637!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000867966596374637!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000959182276982176!GO:0005798;Golgi-associated vesicle;0.000970342777583901!GO:0044431;Golgi apparatus part;0.000994773009211777!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00101352388634606!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00101352388634606!GO:0016564;transcription repressor activity;0.00102476874379207!GO:0000287;magnesium ion binding;0.00113672239723478!GO:0003714;transcription corepressor activity;0.00115013658421352!GO:0051252;regulation of RNA metabolic process;0.00115838049820615!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00115968820120533!GO:0009116;nucleoside metabolic process;0.00116962979488359!GO:0007006;mitochondrial membrane organization and biogenesis;0.00127911583196589!GO:0019899;enzyme binding;0.00132176132168829!GO:0016363;nuclear matrix;0.00151188565419961!GO:0009451;RNA modification;0.00151287349399446!GO:0005048;signal sequence binding;0.00151675024877581!GO:0007093;mitotic cell cycle checkpoint;0.00156641889703603!GO:0031124;mRNA 3'-end processing;0.00158278164959543!GO:0015980;energy derivation by oxidation of organic compounds;0.00162858205193049!GO:0051920;peroxiredoxin activity;0.0016323730499871!GO:0044262;cellular carbohydrate metabolic process;0.00164332116456177!GO:0015631;tubulin binding;0.00170242630519928!GO:0009112;nucleobase metabolic process;0.00176479606854409!GO:0006289;nucleotide-excision repair;0.001830610468362!GO:0031970;organelle envelope lumen;0.0019643258356204!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00200537244665703!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00217112305121224!GO:0048500;signal recognition particle;0.00222872542475855!GO:0043596;nuclear replication fork;0.00229447190385715!GO:0009892;negative regulation of metabolic process;0.00229905067767904!GO:0008276;protein methyltransferase activity;0.00232862918214604!GO:0032259;methylation;0.00234182525745524!GO:0046483;heterocycle metabolic process;0.00238493916515403!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00241440587036689!GO:0006270;DNA replication initiation;0.0024792176879243!GO:0008312;7S RNA binding;0.00248540459453775!GO:0046474;glycerophospholipid biosynthetic process;0.00251391388640985!GO:0006595;polyamine metabolic process;0.00251618772750395!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00257090368356282!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00260853223264902!GO:0015002;heme-copper terminal oxidase activity;0.00260853223264902!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00260853223264902!GO:0004129;cytochrome-c oxidase activity;0.00260853223264902!GO:0003725;double-stranded RNA binding;0.00277179353606394!GO:0048471;perinuclear region of cytoplasm;0.00295204734016588!GO:0000792;heterochromatin;0.00295204734016588!GO:0046966;thyroid hormone receptor binding;0.0030302652924117!GO:0009615;response to virus;0.0030302652924117!GO:0005758;mitochondrial intermembrane space;0.00304952545538811!GO:0016272;prefoldin complex;0.00306726346793425!GO:0016251;general RNA polymerase II transcription factor activity;0.00309316383667087!GO:0032561;guanyl ribonucleotide binding;0.00314757959938671!GO:0019001;guanyl nucleotide binding;0.00314757959938671!GO:0006144;purine base metabolic process;0.00332241993500498!GO:0043488;regulation of mRNA stability;0.0033261633473146!GO:0043487;regulation of RNA stability;0.0033261633473146!GO:0006917;induction of apoptosis;0.00336151557353028!GO:0009303;rRNA transcription;0.00340744525658499!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00346746590674173!GO:0008408;3'-5' exonuclease activity;0.00348985425526205!GO:0048468;cell development;0.00364449011909571!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00364449011909571!GO:0008139;nuclear localization sequence binding;0.00364449011909571!GO:0006497;protein amino acid lipidation;0.00367815787200938!GO:0007052;mitotic spindle organization and biogenesis;0.00370422702650414!GO:0012502;induction of programmed cell death;0.00376102545730438!GO:0006275;regulation of DNA replication;0.00383058631760413!GO:0046822;regulation of nucleocytoplasmic transport;0.00389714273607452!GO:0051540;metal cluster binding;0.00393683786383567!GO:0051536;iron-sulfur cluster binding;0.00393683786383567!GO:0051320;S phase;0.00400382540399411!GO:0051087;chaperone binding;0.00406780882240199!GO:0008629;induction of apoptosis by intracellular signals;0.00414483128081015!GO:0000139;Golgi membrane;0.00417277288250079!GO:0006891;intra-Golgi vesicle-mediated transport;0.00419457206327337!GO:0006284;base-excision repair;0.00419457206327337!GO:0006730;one-carbon compound metabolic process;0.00446442795525305!GO:0000819;sister chromatid segregation;0.00455266191461143!GO:0030176;integral to endoplasmic reticulum membrane;0.00456960196270473!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00456960196270473!GO:0045047;protein targeting to ER;0.00456960196270473!GO:0030384;phosphoinositide metabolic process;0.00465441113521356!GO:0005876;spindle microtubule;0.00481927330473696!GO:0003711;transcription elongation regulator activity;0.00486493610154218!GO:0000070;mitotic sister chromatid segregation;0.00503978681456879!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00514537642316878!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.00519794205037152!GO:0048522;positive regulation of cellular process;0.00536187556663878!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0053817572244377!GO:0031123;RNA 3'-end processing;0.00546547282726249!GO:0051539;4 iron, 4 sulfur cluster binding;0.00551955627523178!GO:0044454;nuclear chromosome part;0.0058871475843804!GO:0042158;lipoprotein biosynthetic process;0.00596467966288336!GO:0050662;coenzyme binding;0.00599000301263975!GO:0031252;leading edge;0.00602628295826431!GO:0051789;response to protein stimulus;0.00605967788141233!GO:0006986;response to unfolded protein;0.00605967788141233!GO:0004532;exoribonuclease activity;0.00611348814889789!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00611348814889789!GO:0000178;exosome (RNase complex);0.00611512215481883!GO:0000725;recombinational repair;0.00614208915868153!GO:0000724;double-strand break repair via homologous recombination;0.00614208915868153!GO:0007017;microtubule-based process;0.00618571227018101!GO:0033116;ER-Golgi intermediate compartment membrane;0.00625510183704137!GO:0003887;DNA-directed DNA polymerase activity;0.00628777393300529!GO:0006505;GPI anchor metabolic process;0.00630669705112318!GO:0043414;biopolymer methylation;0.0065690202628212!GO:0006519;amino acid and derivative metabolic process;0.00668854528467126!GO:0043189;H4/H2A histone acetyltransferase complex;0.00669684091981025!GO:0030663;COPI coated vesicle membrane;0.00675969861642022!GO:0030126;COPI vesicle coat;0.00675969861642022!GO:0006506;GPI anchor biosynthetic process;0.0068203052828983!GO:0031570;DNA integrity checkpoint;0.00683249590178262!GO:0000922;spindle pole;0.00689640150114771!GO:0043022;ribosome binding;0.00703698282540073!GO:0008637;apoptotic mitochondrial changes;0.00737004181781874!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00744127441460384!GO:0019783;small conjugating protein-specific protease activity;0.00753571625429905!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00777948675333869!GO:0022411;cellular component disassembly;0.00793989286075113!GO:0005832;chaperonin-containing T-complex;0.00819796649935657!GO:0008180;signalosome;0.00821955562140517!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00821955562140517!GO:0044440;endosomal part;0.00838689181031741!GO:0010008;endosome membrane;0.00838689181031741!GO:0050178;phenylpyruvate tautomerase activity;0.00838987455239857!GO:0009124;nucleoside monophosphate biosynthetic process;0.00845384946590963!GO:0009123;nucleoside monophosphate metabolic process;0.00845384946590963!GO:0043601;nuclear replisome;0.00846829990702051!GO:0030894;replisome;0.00846829990702051!GO:0032200;telomere organization and biogenesis;0.00847337313697245!GO:0000723;telomere maintenance;0.00847337313697245!GO:0000096;sulfur amino acid metabolic process;0.00850132220756029!GO:0000339;RNA cap binding;0.00852019938866906!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00864391268754289!GO:0030658;transport vesicle membrane;0.00864391268754289!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00897063713384193!GO:0000910;cytokinesis;0.00910640502745707!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00916983842691257!GO:0048487;beta-tubulin binding;0.00919589369002336!GO:0050790;regulation of catalytic activity;0.00921890579341209!GO:0046112;nucleobase biosynthetic process;0.00965570094209931!GO:0051053;negative regulation of DNA metabolic process;0.00974456821798187!GO:0006378;mRNA polyadenylation;0.00996200692547328!GO:0003746;translation elongation factor activity;0.0101746388005321!GO:0004843;ubiquitin-specific protease activity;0.010219622973522!GO:0000123;histone acetyltransferase complex;0.0104278623383625!GO:0035267;NuA4 histone acetyltransferase complex;0.0104653730245167!GO:0019210;kinase inhibitor activity;0.010526319996142!GO:0000781;chromosome, telomeric region;0.0106601948720594!GO:0046983;protein dimerization activity;0.0108908692381823!GO:0031988;membrane-bound vesicle;0.0109497718816326!GO:0006220;pyrimidine nucleotide metabolic process;0.010985124725879!GO:0006807;nitrogen compound metabolic process;0.0110947219808169!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0111730745085532!GO:0004860;protein kinase inhibitor activity;0.0112991377716566!GO:0007040;lysosome organization and biogenesis;0.0114116982676921!GO:0006400;tRNA modification;0.0114555524936443!GO:0030137;COPI-coated vesicle;0.0115042914012852!GO:0005874;microtubule;0.0115325037330967!GO:0007346;regulation of progression through mitotic cell cycle;0.0118152968094244!GO:0048037;cofactor binding;0.0121304903199481!GO:0005669;transcription factor TFIID complex;0.0123658208169267!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.01237715570727!GO:0046426;negative regulation of JAK-STAT cascade;0.0124213445430643!GO:0006007;glucose catabolic process;0.0124610242047959!GO:0006118;electron transport;0.0127406925608939!GO:0005791;rough endoplasmic reticulum;0.0127737672055414!GO:0009308;amine metabolic process;0.0130702043389603!GO:0016584;nucleosome positioning;0.0136598401978172!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0137712383684511!GO:0005869;dynactin complex;0.0138017376114148!GO:0043433;negative regulation of transcription factor activity;0.014267793474414!GO:0042393;histone binding;0.0147582594156445!GO:0008213;protein amino acid alkylation;0.015591792354341!GO:0006479;protein amino acid methylation;0.015591792354341!GO:0030134;ER to Golgi transport vesicle;0.0156079672641103!GO:0009967;positive regulation of signal transduction;0.0157372511022476!GO:0004540;ribonuclease activity;0.0159495365219443!GO:0004221;ubiquitin thiolesterase activity;0.0160748270131021!GO:0051235;maintenance of localization;0.0161943100802036!GO:0045185;maintenance of protein localization;0.0164608845529257!GO:0006740;NADPH regeneration;0.01659130527761!GO:0006098;pentose-phosphate shunt;0.01659130527761!GO:0046519;sphingoid metabolic process;0.016912271118321!GO:0004003;ATP-dependent DNA helicase activity;0.0173189069826931!GO:0008017;microtubule binding;0.0175848237902088!GO:0046365;monosaccharide catabolic process;0.0176625057671779!GO:0030660;Golgi-associated vesicle membrane;0.0176670283397945!GO:0005769;early endosome;0.0177130716702585!GO:0000077;DNA damage checkpoint;0.0179513055447598!GO:0009161;ribonucleoside monophosphate metabolic process;0.0180865557829336!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0180865557829336!GO:0046467;membrane lipid biosynthetic process;0.0181392132457543!GO:0016023;cytoplasmic membrane-bound vesicle;0.0183000986978837!GO:0051223;regulation of protein transport;0.0193779991947328!GO:0004576;oligosaccharyl transferase activity;0.0194157580413886!GO:0004523;ribonuclease H activity;0.0194270405994353!GO:0016407;acetyltransferase activity;0.0194469912711686!GO:0006650;glycerophospholipid metabolic process;0.01945529057276!GO:0008156;negative regulation of DNA replication;0.0194744031934928!GO:0008538;proteasome activator activity;0.019499462565375!GO:0016481;negative regulation of transcription;0.0196576886841614!GO:0008234;cysteine-type peptidase activity;0.0196707822077668!GO:0030118;clathrin coat;0.0204327230893691!GO:0033261;regulation of progression through S phase;0.021190041538907!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0212315090752678!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0212315090752678!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0212315090752678!GO:0005774;vacuolar membrane;0.0212315090752678!GO:0000726;non-recombinational repair;0.0213328802313024!GO:0000793;condensed chromosome;0.0213571479142312!GO:0008250;oligosaccharyl transferase complex;0.0215840723204814!GO:0030833;regulation of actin filament polymerization;0.0217414742542379!GO:0000084;S phase of mitotic cell cycle;0.0222600811365679!GO:0003702;RNA polymerase II transcription factor activity;0.0223653202425221!GO:0046128;purine ribonucleoside metabolic process;0.0224358104568934!GO:0042278;purine nucleoside metabolic process;0.0224358104568934!GO:0030224;monocyte differentiation;0.0224358104568934!GO:0005996;monosaccharide metabolic process;0.0224687340445651!GO:0006376;mRNA splice site selection;0.0225215860838933!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0225215860838933!GO:0008630;DNA damage response, signal transduction resulting in induction of apoptosis;0.0228425478872565!GO:0008536;Ran GTPase binding;0.0231194993211555!GO:0032507;maintenance of cellular protein localization;0.0232009081765582!GO:0006607;NLS-bearing substrate import into nucleus;0.0232635523716107!GO:0019320;hexose catabolic process;0.0232635523716107!GO:0019318;hexose metabolic process;0.0232635523716107!GO:0009396;folic acid and derivative biosynthetic process;0.0237817778796658!GO:0006672;ceramide metabolic process;0.0238587795005012!GO:0000175;3'-5'-exoribonuclease activity;0.0239544231786462!GO:0009066;aspartate family amino acid metabolic process;0.0240668268328342!GO:0008601;protein phosphatase type 2A regulator activity;0.0241389139318893!GO:0016301;kinase activity;0.0243006650705406!GO:0000152;nuclear ubiquitin ligase complex;0.0244418646354341!GO:0031371;ubiquitin conjugating enzyme complex;0.024812858538143!GO:0005663;DNA replication factor C complex;0.0251907328233996!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0253320685133523!GO:0030119;AP-type membrane coat adaptor complex;0.0258027153242777!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0259913140075686!GO:0010257;NADH dehydrogenase complex assembly;0.0259913140075686!GO:0033108;mitochondrial respiratory chain complex assembly;0.0259913140075686!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0263447876536237!GO:0030508;thiol-disulfide exchange intermediate activity;0.026502891316748!GO:0007050;cell cycle arrest;0.0266214808367954!GO:0007033;vacuole organization and biogenesis;0.0267202142514424!GO:0007259;JAK-STAT cascade;0.0269706276793594!GO:0046164;alcohol catabolic process;0.0277239481023909!GO:0016790;thiolester hydrolase activity;0.0277469507724401!GO:0016569;covalent chromatin modification;0.0281811821870128!GO:0005765;lysosomal membrane;0.028249304462559!GO:0004177;aminopeptidase activity;0.0287752193910301!GO:0030132;clathrin coat of coated pit;0.0292135700297544!GO:0051651;maintenance of cellular localization;0.0292279288772889!GO:0032039;integrator complex;0.0298869364265766!GO:0051338;regulation of transferase activity;0.03008192108914!GO:0046979;TAP2 binding;0.0305230788983011!GO:0046977;TAP binding;0.0305230788983011!GO:0046978;TAP1 binding;0.0305230788983011!GO:0006458;'de novo' protein folding;0.0308614915029189!GO:0051084;'de novo' posttranslational protein folding;0.0308614915029189!GO:0030127;COPII vesicle coat;0.0310734423402315!GO:0012507;ER to Golgi transport vesicle membrane;0.0310734423402315!GO:0051287;NAD binding;0.0310734423402315!GO:0044450;microtubule organizing center part;0.0314586031936016!GO:0006518;peptide metabolic process;0.0317483394812343!GO:0042054;histone methyltransferase activity;0.0322483208292182!GO:0000159;protein phosphatase type 2A complex;0.0325536702348483!GO:0005652;nuclear lamina;0.0326908358851093!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.032906429569049!GO:0016788;hydrolase activity, acting on ester bonds;0.0340333539703519!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0347213265661313!GO:0042157;lipoprotein metabolic process;0.0348742740435503!GO:0008287;protein serine/threonine phosphatase complex;0.0348742740435503!GO:0044437;vacuolar part;0.0351506187007396!GO:0030911;TPR domain binding;0.0355301448781173!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0361976649308211!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0361976649308211!GO:0009067;aspartate family amino acid biosynthetic process;0.0369776470988588!GO:0005732;small nucleolar ribonucleoprotein complex;0.0371394778859781!GO:0000060;protein import into nucleus, translocation;0.0372498467259562!GO:0048144;fibroblast proliferation;0.0375198848511224!GO:0048145;regulation of fibroblast proliferation;0.0375198848511224!GO:0016279;protein-lysine N-methyltransferase activity;0.0377268937172078!GO:0018024;histone-lysine N-methyltransferase activity;0.0377268937172078!GO:0016278;lysine N-methyltransferase activity;0.0377268937172078!GO:0047485;protein N-terminus binding;0.0378160092124178!GO:0006406;mRNA export from nucleus;0.0386290127713645!GO:0008022;protein C-terminus binding;0.0386355196196248!GO:0000209;protein polyubiquitination;0.0386839356915034!GO:0030131;clathrin adaptor complex;0.0387218252210631!GO:0005666;DNA-directed RNA polymerase III complex;0.0387884759798969!GO:0007010;cytoskeleton organization and biogenesis;0.0394251243200684!GO:0035035;histone acetyltransferase binding;0.0396819039671917!GO:0006596;polyamine biosynthetic process;0.0398053880396341!GO:0003756;protein disulfide isomerase activity;0.0401313437108063!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0401313437108063!GO:0008320;protein transmembrane transporter activity;0.040155813042001!GO:0043549;regulation of kinase activity;0.040155813042001!GO:0001832;blastocyst growth;0.040155813042001!GO:0030133;transport vesicle;0.0406203732372112!GO:0006338;chromatin remodeling;0.0406626082031063!GO:0030433;ER-associated protein catabolic process;0.0414830700232155!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0414830700232155!GO:0031625;ubiquitin protein ligase binding;0.0414830700232155!GO:0051348;negative regulation of transferase activity;0.0424301143191828!GO:0004659;prenyltransferase activity;0.042450592302812!GO:0016615;malate dehydrogenase activity;0.0424590822826016!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0425829430390859!GO:0051101;regulation of DNA binding;0.0428717004628851!GO:0016197;endosome transport;0.0430433957529138!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0431358250329231!GO:0008537;proteasome activator complex;0.0431816948437168!GO:0031982;vesicle;0.0432832769765816!GO:0015036;disulfide oxidoreductase activity;0.0434050793669505!GO:0018193;peptidyl-amino acid modification;0.0434757014018238!GO:0031647;regulation of protein stability;0.0434757014018238!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0434838702001606!GO:0006301;postreplication repair;0.0435165192190176!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0435165192190176!GO:0016791;phosphoric monoester hydrolase activity;0.0436415453720795!GO:0001824;blastocyst development;0.0442227023655837!GO:0003893;epsilon DNA polymerase activity;0.0446135560656716!GO:0007253;cytoplasmic sequestering of NF-kappaB;0.0469452705621899!GO:0006096;glycolysis;0.0471183753819885!GO:0016311;dephosphorylation;0.0474249985042227!GO:0043631;RNA polyadenylation;0.0478543886178297!GO:0048146;positive regulation of fibroblast proliferation;0.0485705018747929!GO:0033673;negative regulation of kinase activity;0.0487798354518991!GO:0006469;negative regulation of protein kinase activity;0.0487798354518991!GO:0031577;spindle checkpoint;0.0489694327517209!GO:0051059;NF-kappaB binding;0.0490834926661347!GO:0008097;5S rRNA binding;0.0497776939578962!GO:0018196;peptidyl-asparagine modification;0.0499848657840257!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0499848657840257!GO:0000790;nuclear chromatin;0.0499848657840257!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0499848657840257!GO:0045039;protein import into mitochondrial inner membrane;0.0499848657840257 | |||
|sample_id=10795 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=RORA:1.99004417418;STAT2,4,6:1.89207230724;PITX1..3:1.67302994274;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.51248828305;MYB:1.50714663533;E2F1..5:1.48796679996;POU2F1..3:1.37497737004;AIRE:1.34916949614;YY1:1.26928235517;ELK1,4_GABP{A,B1}:1.22838791269;NKX6-1,2:1.19926725826;NRF1:1.04421072281;TOPORS:1.00900158984;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.946866536777;HIF1A:0.932512691852;NR5A1,2:0.913613420423;HOX{A6,A7,B6,B7}:0.90961671042;bHLH_family:0.841350373659;FOXP1:0.777163400109;STAT5{A,B}:0.729235357523;ELF1,2,4:0.728262232023;CREB1:0.704866824524;RFX2..5_RFXANK_RFXAP:0.678514184229;TEF:0.605847325071;ZNF143:0.585148947532;PAX4:0.583824640483;GFI1:0.545357942436;IKZF2:0.541043429329;TFDP1:0.535466586381;PAX3,7:0.513283691132;CEBPA,B_DDIT3:0.508129272023;ESRRA:0.470984566687;ATF4:0.469167321962;HES1:0.464915167437;IRF1,2:0.463219221614;VSX1,2:0.452645546497;POU1F1:0.450599192491;CUX2:0.415322413406;RUNX1..3:0.39297757058;IRF7:0.377230241832;ZBTB16:0.360937476028;CDX1,2,4:0.350659829862;NFE2:0.340180919639;NR1H4:0.313239696596;TLX2:0.31323847798;SPI1:0.286689958922;PRRX1,2:0.276009873452;FOS_FOS{B,L1}_JUN{B,D}:0.252693188727;FOXM1:0.218757536525;NFE2L2:0.215225664401;NKX3-1:0.197727763279;PAX8:0.185033466343;DMAP1_NCOR{1,2}_SMARC:0.156695582046;NKX3-2:0.142624875596;POU3F1..4:0.132832947912;GATA6:0.129645621761;CRX:0.118974359203;OCT4_SOX2{dimer}:0.118223850308;BACH2:0.114320503602;ATF5_CREB3:0.110840500071;ADNP_IRX_SIX_ZHX:0.109681554813;NFE2L1:0.0960121517918;NANOG{mouse}:0.0843806475538;AHR_ARNT_ARNT2:0.0696533993262;SPIB:0.0659252864622;HLF:0.0654069570907;SOX17:0.0577935268239;BREu{core}:0.0532110817186;TAL1_TCF{3,4,12}:0.0469940283056;HAND1,2:0.0453033119615;NFY{A,B,C}:0.0444945514986;FOXA2:0.0339000898361;FOXD3:0.0331705121838;HOXA9_MEIS1:0.0304473404263;FOXP3:0.0299404973411;ETS1,2:0.0261314064052;FOSL2:0.0222389503881;NKX2-1,4:0.0210748077038;NANOG:0.0195194014898;EN1,2:0.0176943640611;PAX2:-0.00140090236467;GFI1B:-0.00192254150014;ONECUT1,2:-0.00853838138605;FOX{I1,J2}:-0.0152331320738;SOX{8,9,10}:-0.0269983038675;ZEB1:-0.049335454223;ARID5B:-0.112750401759;UFEwm:-0.115007888837;HNF1A:-0.188099365219;PAX6:-0.192572324245;NFKB1_REL_RELA:-0.202782747335;NFIL3:-0.216031988779;ESR1:-0.222860288334;PAX1,9:-0.223760410189;RFX1:-0.237580680918;ZNF384:-0.241464222;NR6A1:-0.270886543608;PPARG:-0.281855504159;MYOD1:-0.291477698925;HNF4A_NR2F1,2:-0.29995903251;LMO2:-0.333565577921;ALX1:-0.34990176721;CDC5L:-0.371870197129;SNAI1..3:-0.398436200569;GCM1,2:-0.412940348852;PBX1:-0.421011634478;NKX2-2,8:-0.42215402691;POU5F1:-0.433303701662;TGIF1:-0.455537390308;EP300:-0.470470917344;TP53:-0.484281741776;HOX{A5,B5}:-0.485210208491;RBPJ:-0.496815628425;FOX{F1,F2,J1}:-0.501195607452;ZNF423:-0.504900019109;DBP:-0.514084000062;FOXN1:-0.518060775417;REST:-0.557511130756;JUN:-0.573557863266;GTF2A1,2:-0.612906726358;HSF1,2:-0.632484099772;BPTF:-0.632843526829;RXRA_VDR{dimer}:-0.632851499008;GZF1:-0.642914805754;KLF4:-0.685251208833;EVI1:-0.686385306354;ATF6:-0.708397488747;ATF2:-0.721774216794;MYFfamily:-0.729827780482;ZIC1..3:-0.730697120331;MEF2{A,B,C,D}:-0.756205751484;NKX2-3_NKX2-5:-0.769733246477;GATA4:-0.778922671399;STAT1,3:-0.791873201454;TBP:-0.821985220001;SOX5:-0.831687441267;ZFP161:-0.832405605898;XBP1:-0.839570073142;FOXQ1:-0.848969956248;IKZF1:-0.864773993023;HOX{A4,D4}:-0.874093191252;ZNF148:-0.896653260181;POU6F1:-0.905386184232;ALX4:-0.918403910921;LEF1_TCF7_TCF7L1,2:-0.94656333382;NFIX:-0.957234477824;TFAP4:-0.98199018494;FOXL1:-0.99688712149;HMX1:-1.01710509076;MZF1:-1.06267951887;HIC1:-1.06541617383;AR:-1.10089286847;SP1:-1.15495894717;SOX2:-1.15956142387;TFAP2B:-1.16884405768;MED-1{core}:-1.17231781454;ZBTB6:-1.182675761;FOX{D1,D2}:-1.19628562612;MYBL2:-1.19939651972;TEAD1:-1.21163699126;SRF:-1.23164507034;LHX3,4:-1.23694002432;TFAP2{A,C}:-1.27163480823;NFATC1..3:-1.34463229753;PRDM1:-1.35840827756;RXR{A,B,G}:-1.35934582516;PATZ1:-1.36040557395;MTF1:-1.36406939966;NHLH1,2:-1.38623260653;GLI1..3:-1.3945790767;MAFB:-1.40750666975;PAX5:-1.41329981223;SREBF1,2:-1.42274077417;XCPE1{core}:-1.43365408719;EGR1..3:-1.45296741102;TLX1..3_NFIC{dimer}:-1.46404324353;GTF2I:-1.47453177849;MAZ:-1.49347722393;EBF1:-1.53770741673;HMGA1,2:-1.54565869625;ZNF238:-1.56969540651;RREB1:-1.57171064027;TBX4,5:-1.5843517216;PDX1:-1.58843846863;MTE{core}:-1.6263148523;HBP1_HMGB_SSRP1_UBTF:-1.668832337;T:-1.68971520345;FOXO1,3,4:-1.79385610957;TFCP2:-1.87263386517;NR3C1:-2.05547821954;SMAD1..7,9:-2.31262590381;SPZ1:-2.68441035328 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10795-110I3;search_select_hide=table117:FF:10795-110I3 | |||
}} | }} |
Latest revision as of 15:05, 3 June 2020
Name: | anaplastic large cell lymphoma cell line:Ki-JK |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11881 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11881
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11881
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.018 |
10 | 10 | 0.014 |
100 | 100 | 0.0229 |
101 | 101 | 0.534 |
102 | 102 | 0.371 |
103 | 103 | 0.308 |
104 | 104 | 0.793 |
105 | 105 | 0.631 |
106 | 106 | 0.594 |
107 | 107 | 0.275 |
108 | 108 | 0.719 |
109 | 109 | 0.00369 |
11 | 11 | 0.0352 |
110 | 110 | 0.138 |
111 | 111 | 0.327 |
112 | 112 | 0.617 |
113 | 113 | 0.932 |
114 | 114 | 0.24 |
115 | 115 | 0.656 |
116 | 116 | 0.125 |
117 | 117 | 0.00433 |
118 | 118 | 0.0619 |
119 | 119 | 0.266 |
12 | 12 | 0.749 |
120 | 120 | 0.354 |
121 | 121 | 0.154 |
122 | 122 | 0.467 |
123 | 123 | 2.56098e-4 |
124 | 124 | 0.629 |
125 | 125 | 0.599 |
126 | 126 | 0.528 |
127 | 127 | 0.655 |
128 | 128 | 0.263 |
129 | 129 | 0.32 |
13 | 13 | 0.0296 |
130 | 130 | 0.754 |
131 | 131 | 0.9 |
132 | 132 | 0.668 |
133 | 133 | 0.293 |
134 | 134 | 0.811 |
135 | 135 | 0.314 |
136 | 136 | 0.0724 |
137 | 137 | 0.656 |
138 | 138 | 0.147 |
139 | 139 | 0.303 |
14 | 14 | 0.875 |
140 | 140 | 0.198 |
141 | 141 | 0.96 |
142 | 142 | 0.361 |
143 | 143 | 0.011 |
144 | 144 | 0.821 |
145 | 145 | 0.781 |
146 | 146 | 0.708 |
147 | 147 | 0.328 |
148 | 148 | 0.0868 |
149 | 149 | 0.255 |
15 | 15 | 0.0835 |
150 | 150 | 0.941 |
151 | 151 | 0.767 |
152 | 152 | 0.291 |
153 | 153 | 0.922 |
154 | 154 | 0.804 |
155 | 155 | 0.134 |
156 | 156 | 0.48 |
157 | 157 | 0.618 |
158 | 158 | 0.657 |
159 | 159 | 0.812 |
16 | 16 | 0.955 |
160 | 160 | 0.299 |
161 | 161 | 0.572 |
162 | 162 | 0.141 |
163 | 163 | 0.722 |
164 | 164 | 0.0137 |
165 | 165 | 0.643 |
166 | 166 | 0.264 |
167 | 167 | 0.0377 |
168 | 168 | 0.374 |
169 | 169 | 0.118 |
17 | 17 | 0.726 |
18 | 18 | 0.225 |
19 | 19 | 0.739 |
2 | 2 | 0.407 |
20 | 20 | 0.107 |
21 | 21 | 0.102 |
22 | 22 | 0.92 |
23 | 23 | 0.463 |
24 | 24 | 0.257 |
25 | 25 | 0.15 |
26 | 26 | 0.0125 |
27 | 27 | 0.812 |
28 | 28 | 0.898 |
29 | 29 | 0.0434 |
3 | 3 | 0.154 |
30 | 30 | 0.0625 |
31 | 31 | 0.488 |
32 | 32 | 0.542 |
33 | 33 | 0.332 |
34 | 34 | 0.452 |
35 | 35 | 0.424 |
36 | 36 | 0.0292 |
37 | 37 | 0.241 |
38 | 38 | 0.578 |
39 | 39 | 0.537 |
4 | 4 | 0.89 |
40 | 40 | 0.141 |
41 | 41 | 0.879 |
42 | 42 | 0.156 |
43 | 43 | 0.642 |
44 | 44 | 0.0298 |
45 | 45 | 0.313 |
46 | 46 | 0.526 |
47 | 47 | 0.0219 |
48 | 48 | 0.0357 |
49 | 49 | 0.354 |
5 | 5 | 0.768 |
50 | 50 | 0.954 |
51 | 51 | 0.808 |
52 | 52 | 0.0835 |
53 | 53 | 0.408 |
54 | 54 | 0.716 |
55 | 55 | 0.695 |
56 | 56 | 0.945 |
57 | 57 | 0.149 |
58 | 58 | 0.292 |
59 | 59 | 0.937 |
6 | 6 | 0.432 |
60 | 60 | 0.971 |
61 | 61 | 0.206 |
62 | 62 | 0.0754 |
63 | 63 | 0.438 |
64 | 64 | 0.127 |
65 | 65 | 0.998 |
66 | 66 | 0.249 |
67 | 67 | 0.957 |
68 | 68 | 0.379 |
69 | 69 | 0.538 |
7 | 7 | 0.294 |
70 | 70 | 0.097 |
71 | 71 | 0.0784 |
72 | 72 | 0.418 |
73 | 73 | 0.386 |
74 | 74 | 0.592 |
75 | 75 | 0.00767 |
76 | 76 | 0.0501 |
77 | 77 | 0.736 |
78 | 78 | 0.113 |
79 | 79 | 0.345 |
8 | 8 | 0.153 |
80 | 80 | 0.157 |
81 | 81 | 0.397 |
82 | 82 | 0.363 |
83 | 83 | 0.836 |
84 | 84 | 0.658 |
85 | 85 | 0.706 |
86 | 86 | 0.335 |
87 | 87 | 0.237 |
88 | 88 | 0.754 |
89 | 89 | 0.934 |
9 | 9 | 0.45 |
90 | 90 | 0.00892 |
91 | 91 | 0.85 |
92 | 92 | 0.591 |
93 | 93 | 0.851 |
94 | 94 | 0.287 |
95 | 95 | 0.00261 |
96 | 96 | 0.191 |
97 | 97 | 0.168 |
98 | 98 | 0.214 |
99 | 99 | 0.594 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11881
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
CL:0000084 T cell
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0104868 anaplastic large cell lymphoma cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000084 (T cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
0060058 (lymphoma)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100104 (lymphoma cell line sample)
0104868 (anaplastic large cell lymphoma cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)