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{{f5samples
{{f5samples
|id=FF:10821-111C2
|DRA_sample_Accession=CAGE@SAMD00005328
|name=B lymphoblastoid cell line: GM12878 ENCODE, biol_rep1
|accession_numbers=CAGE;DRX007776;DRR008648;DRZ000073;DRZ001458;DRZ011423;DRZ012808
|sample_id=10821
|ancestors_in_anatomy_facet=
|rna_tube_id=111C2
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000542,CL:0000219,CL:0000945,CL:0000738,CL:0002087,CL:0002242,CL:0000255
|rna_box=111
|rna_position=C2
|sample_cell_lot=
|sample_cell_catalog=
|sample_company=
|rna_lot_number=
|rna_catalog_number=
|sample_species=
|sample_strain=
|sample_dev_stage=
|sample_tissue=blood
|sample_donor(cell lot)=
|sample_sex=female
|sample_age=
|sample_ethnicity=
|rna_rin=
|rna_od260/230=2.15
|rna_od260/280=2.09
|sample_cell_type=b cell
|sample_cell_line=GM12878
|sample_collaboration=Carrie Davis (Cold spring Harbor Laboratories)
|sample_experimental_condition=
|sample_disease=
|rna_sample_type=total RNA
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_weight_ug=25.8955
|rna_concentration=0.51791
|sample_note=
|profile_hcage=CNhs12331,LSID913,release011,COMPLETED
|profile_cagescan=,,,
|profile_srnaseq=,,,
|profile_rnaseq=,,,
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000051,CL:0000063,CL:0000134,CL:0000144,CL:0000219,CL:0000255,CL:0000542,CL:0000548,CL:0000566,CL:0000723,CL:0000738,CL:0000826,CL:0000837,CL:0000838,CL:0000945,CL:0000988,CL:0002031,CL:0002032,CL:0002087,CL:0002320,CL:0002371
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|sample_description=
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0101035,FF:0100773,FF:0101522,FF:0102062
|comment=
|created_by=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|expression_enrichment_score=chr6:391743..391759,+!p1@IRF4!2.60!395.59!IRF4;;chr2:68592406..68592424,+!p1@PLEK!2.46!288.23!PLEK;;chr11:111249993..111250006,-!p1@POU2AF1!2.37!235.43!POU2AF1;;chr16:85932760..85932775,+!p1@IRF8!2.07!117.22!IRF8;;chr19:50922187..50922204,+!p1@SPIB!2.05!111.79!SPIB;;chr1:25291475..25291511,-!p2@RUNX3!2.04!107.59!RUNX3;;chr12:103351444..103351461,+!p1@ASCL1!1.89!77.41!ASCL1;;chr17:38020392..38020477,-!p1@IKZF3!1.84!68.31!IKZF3;;chr2:231090433..231090469,+!p1@SP140!1.83!67.01!SP140;;chr3:27763807..27763822,-!p1@EOMES!1.77!57.46!EOMES;;chr1:25256756..25256774,-!p1@RUNX3!1.72!94.52!RUNX3;;chr2:231090471..231090504,+!p2@SP140!1.71!50.20!SP140;;chr2:68592394..68592405,+!p2@PLEK!1.69!47.53!PLEK;;chr7:28610099..28610113,+!p5@CREB5!1.69!47.53!CREB5;;chr19:36204309..36204335,+!p1@ZBTB32!1.59!38.28!ZBTB32;;chr10:64576105..64576133,-!p1@EGR2!1.56!71.68!EGR2;;chr1:158978768..158978800,+!p8@IFI16!1.53!33.09!IFI16;;chr8:76319876..76319926,+!p1@HNF4G!1.52!32.40!HNF4G;;chr17:36105042..36105060,-!p1@HNF1B!1.50!30.72!HNF1B;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.46!27.81!ZBED1;;chr14:75988771..75988826,+!p1@BATF!1.45!35.76!BATF;;chr3:27764190..27764208,-!p2@EOMES!1.43!25.67!EOMES;;chr5:88120151..88120177,-!p6@MEF2C!1.42!25.52!MEF2C;;chr11:61520075..61520136,+!p1@C11orf9!1.41!50.97!C11orf9;;chr19:42636586..42636607,-!p1@POU2F2!1.40!65.94!POU2F2;;chr20:50159198..50159299,-!p1@NFATC2!1.40!34.77!NFATC2;;chr11:47400078..47400106,-!p1@SPI1!1.40!24.38!SPI1;;chr1:3569072..3569093,+!p1@TP73!1.40!24.15!TP73;;chr12:103352277..103352324,+!p2@ASCL1!1.38!23.08!ASCL1;;chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!1.34!20.94!MEF2B;;chr4:185395590..185395627,-!p3@IRF2!1.32!24.61!IRF2;;chr7:50348268..50348366,+!p4@IKZF1!1.32!19.71!IKZF1;;chr5:142780237..142780261,-!p7@NR3C1!1.31!19.64!NR3C1;;chr3:189349162..189349207,+!p2@TP63!1.31!19.64!TP63;;chr9:37034469..37034474,-!p1@PAX5!1.30!19.10!PAX5;;chr17:45810594..45810608,+!p1@TBX21!1.27!17.80!TBX21;;chr5:158526917..158526932,-!p1@EBF1!1.26!42.26!EBF1;;chr8:76319850..76319870,+!p4@HNF4G!1.26!17.12!HNF4G;;chr18:52989031..52989079,-!p2@TCF4!1.24!38.59!TCF4;;chr7:28610060..28610073,+!p9@CREB5!1.24!16.28!CREB5;;chr5:133450365..133450444,+!p1@TCF7!1.21!68.70!TCF7;;chr3:101546827..101546847,+!p2@NFKBIZ!1.21!21.24!NFKBIZ;;chr2:214015111..214015179,-!p1@IKZF2!1.20!26.21!IKZF2;;chr8:72756637..72756664,-!p3@MSC!1.20!17.04!MSC;;chr13:41593425..41593480,-!p1@ELF1!1.18!88.56!ELF1;;chr8:72756667..72756736,-!p2@MSC!1.18!22.24!MSC;;chr11:615570..615721,-!p2@IRF7!1.16!26.52!IRF7;;chr14:75988831..75988847,+!p2@BATF!1.16!13.45!BATF;;chr12:54447599..54447630,+!p3@HOXC4!1.15!15.97!HOXC4;;chr9:1050331..1050363,+!p1@DMRT2!1.14!12.91!DMRT2;;chr2:68615031..68615055,+!p3@PLEK!1.13!12.61!PLEK;;chr2:214015343..214015366,-!p3@IKZF2!1.13!12.38!IKZF2;;chr6:34204973..34204990,+!p4@HMGA1!1.11!159.70!HMGA1;;chr5:142780189..142780223,-!p6@NR3C1!1.11!12.00!NR3C1;;chr9:126774018..126774055,+!p1@LHX2!1.11!11.92!LHX2;;chr20:62680984..62680999,-!p1@SOX18!1.10!15.44!SOX18;;chr5:88178983..88179012,-!p1@MEF2C!1.09!87.26!MEF2C;;chr19:45579725..45579743,-!p1@ZNF296!1.09!51.66!ZNF296;;chr7:128577972..128578047,+!p1@IRF5!1.09!18.03!IRF5;;chr8:135614084..135614119,-!p4@ZFAT!1.08!11.16!ZFAT;;chr16:85936412..85936431,+!p2@IRF8!1.08!11.16!IRF8;;chr1:170632115..170632136,+!p9@PRRX1!1.08!11.08!PRRX1;;chr7:50343634..50343717,+!p2@IKZF1!1.08!11.00!IKZF1;;chr20:42543441..42543497,+!p1@TOX2!1.07!48.22!TOX2;;chr9:117150254..117150271,-!p1@AKNA!1.05!28.43!AKNA;;chr11:19262421..19262455,-!p3@E2F8!1.04!9.86!E2F8;;chr2:214016254..214016282,-!p7@IKZF2!1.03!9.63!IKZF2;;chr8:72756063..72756125,-!p1@MSC!1.02!19.33!MSC;;chr7:50344251..50344288,+!p3@IKZF1!1.02!9.55!IKZF1;;chr9:126773880..126773895,+!p2@LHX2!1.02!9.55!LHX2;;chr2:231090344..231090361,-!p3@SP110!1.02!9.48!SP110;;chr10:104155480..104155534,+!p2@NFKB2!1.01!60.75!NFKB2;;chr3:141105705..141105770,+!p4@ZBTB38!1.00!11.00!ZBTB38;;chr3:141747950..141748004,-!p7@TFDP2!1.00!9.02!TFDP2;;chr1:25291620..25291635,-!p4@RUNX3!1.00!9.02!RUNX3;;chr1:23857698..23857733,-!p1@E2F2!0.99!16.28!E2F2;;chr1:151319654..151319698,-!p2@RFX5!0.98!19.18!RFX5;;chr19:42627037..42627084,-!p3@POU2F2!0.98!8.56!POU2F2;;chr7:137620684..137620711,-!p4@CREB3L2!0.97!8.25!CREB3L2;;chr1:158979686..158979745,+!p1@IFI16!0.96!274.32!IFI16;;chr16:85936539..85936562,+!p3@IRF8!0.96!8.18!IRF8;;chr7:137620650..137620677,-!p3@CREB3L2!0.96!8.10!CREB3L2;;chr1:38512457..38512474,-!p1@POU3F1!0.95!8.79!POU3F1;;chr4:185395633..185395651,-!p2@IRF2!0.94!12.68!IRF2;;chr1:3569135..3569150,+!p3@TP73!0.94!7.79!TP73;;chr6:41700616..41700664,-!p8@TFEB!0.94!7.79!TFEB;;chr6:44233252..44233296,-!p1@NFKBIE!0.93!76.41!NFKBIE;;chr8:22550982..22550999,-!p1@EGR3!0.93!21.93!EGR3;;chr2:70314240..70314256,+!p4@PCBP1!0.93!15.89!PCBP1;;chr8:65492915..65492932,+!p1@BHLHE22!0.93!7.49!BHLHE22;;chr17:37934204..37934241,-!p3@IKZF3!0.93!7.49!IKZF3;;chr12:11802753..11802834,+!p2@ETV6!0.91!36.68!ETV6;;chr17:1959369..1959388,+!p2@HIC1!0.91!19.49!HIC1;;chr5:142780280..142780294,-!p16@NR3C1!0.91!7.11!NR3C1;;chr7:50344289..50344323,+!p1@IKZF1!0.90!7.03!IKZF1;;chr10:104154246..104154347,+!p3@NFKB2!0.89!43.17!NFKB2;;chr1:117602932..117602973,+!p1@TTF2!0.89!26.74!TTF2;;chr12:54785074..54785122,-!p2@ZNF385A!0.89!10.62!ZNF385A;;chr6:144385698..144385742,-!p2@PLAGL1!0.89!8.33!PLAGL1;;chr6:43337124..43337144,-!p4@ZNF318!0.88!9.48!ZNF318;;chr6:135502408..135502459,+!p2@MYB!0.88!7.72!MYB;;chr1:201979703..201979721,+!p2@ELF3!0.88!6.57!ELF3;;chr15:74833584..74833626,+!p1@ARID3B!0.87!15.44!ARID3B;;chr17:36105074..36105086,-!p2@HNF1B!0.87!6.50!HNF1B;;chr1:92951607..92951661,-!p1@GFI1!0.87!6.50!GFI1;;chr17:38020557..38020572,-!p4@IKZF3!0.87!6.42!IKZF3;;chr20:42295745..42295765,+!p1@MYBL2!0.86!107.67!MYBL2;;chr20:42295713..42295738,+!p2@MYBL2!0.86!39.51!MYBL2;;chr5:158526756..158526797,-!p3@EBF1!0.86!6.27!EBF1;;chr17:41623692..41623715,-!p1@ETV4!0.85!27.59!ETV4;;chr6:126240380..126240430,+!p2@NCOA7!0.85!16.58!NCOA7;;chr18:52989001..52989030,-!p10@TCF4!0.85!6.72!TCF4;;chr9:16728161..16728185,-!p4@BNC2!0.85!6.11!BNC2;;chr2:214013461..214013517,-!p6@IKZF2!0.85!6.04!IKZF2;;chr9:20622444..20622468,-!p2@MLLT3!0.84!20.17!MLLT3;;chr7:156803329..156803362,-!p1@MNX1!0.84!5.96!MNX1;;chr8:135614120..135614149,-!p5@ZFAT!0.84!5.88!ZFAT;;chr19:42636625..42636632,-!p2@POU2F2!0.84!5.88!POU2F2;;chr7:64126503..64126528,+!p1@ZNF107!0.83!44.09!ZNF107;;chr1:167298300..167298319,+!p2@POU2F1!0.83!5.73!POU2F1;;chr1:170632051..170632081,+!p16@PRRX1!0.83!5.73!PRRX1;;chr1:6884943..6884957,+!p7@CAMTA1!0.83!5.73!CAMTA1;;chr2:231084659..231084721,-!p1@SP110!0.82!140.45!SP110;;chr17:70117153..70117174,+!p1@SOX9!0.82!62.43!SOX9;;chr14:74226961..74227020,-!p1@C14orf43!0.82!39.73!C14orf43;;chr3:141103634..141103665,+!p18@ZBTB38!0.82!5.65!ZBTB38;;chr17:41739283..41739297,-!p1@MEOX1!0.82!5.58!MEOX1;;chr6:43337180..43337244,-!p1@ZNF318!0.81!22.69!ZNF318;;chr1:27023752..27023799,+!p4@ARID1A!0.81!7.34!ARID1A;;chr12:54447219..54447237,+!p6@HOXC4!0.81!5.50!HOXC4;;chr9:128509878..128509902,+!p5@PBX3!0.81!5.50!PBX3;;chr8:76452097..76452126,+!p2@HNF4G!0.81!5.43!HNF4G;;chr19:50432453..50432468,+!p1@ATF5!0.80!326.97!ATF5;;chr9:20622478..20622525,-!p1@MLLT3!0.80!45.47!MLLT3;;chr19:45252008..45252024,+!p2@BCL3!0.79!18.26!BCL3;;chr17:46655730..46655791,-!p1@HOXB4!0.79!13.68!HOXB4;;chr4:87857491..87857519,+!p10@AFF1!0.79!7.26!AFF1;;chr17:40440359..40440386,+!p4@STAT5A!0.79!5.12!STAT5A;;chr1:156460436..156460462,-!p7@MEF2D!0.79!5.12!MEF2D;;chr1:3568889..3568900,+!p7@TP73!0.79!5.12!TP73;;chr1:3569101..3569115,+!p2@TP73!0.79!5.12!TP73;;chr5:138609782..138609826,+!p5@MATR3!0.78!35.76!MATR3;;chr17:41277372..41277418,-!p1@BRCA1!0.78!19.71!BRCA1;;chr6:135502501..135502546,+!p1@MYB!0.78!6.11!MYB;;chr18:42260840..42260860,+!p2@SETBP1!0.78!4.97!SETBP1;;chr6:20402102..20402152,+!p1@E2F3!0.77!21.62!E2F3;;chr5:88179017..88179046,-!p2@MEF2C!0.77!21.24!MEF2C;;chr19:19729477..19729542,-!p1@PBX4!0.77!11.00!PBX4;;chr1:212873267..212873332,-!p1@BATF3!0.77!6.88!BATF3;;chr12:54447637..54447659,+!p4@HOXC4!0.77!4.89!HOXC4;;chr6:44228288..44228303,-!p9@NFKBIE!0.77!4.89!NFKBIE;;chr16:31885093..31885165,+!p1@ZNF267!0.76!81.23!ZNF267;;chr2:68615063..68615089,+!p4@PLEK!0.76!4.81!PLEK;;chr3:141747459..141747475,-!p1@TFDP2!0.75!42.64!TFDP2;;chr4:185395191..185395226,-!p4@IRF2!0.75!6.65!IRF2;;chr3:27761692..27761705,-!p4@EOMES!0.75!4.66!EOMES;;chr8:135613895..135613921,-!p8@ZFAT!0.75!4.66!ZFAT;;chr1:170632137..170632172,+!p10@PRRX1!0.75!4.66!PRRX1;;chr11:615942..615957,-!p1@IRF7!0.74!47.07!IRF7;;chr4:146859626..146859669,-!p2@ZNF827!0.74!6.88!ZNF827;;chr8:76452129..76452159,+!p5@HNF4G!0.74!4.51!HNF4G;;chr9:16728327..16728338,-!p5@BNC2!0.74!4.51!BNC2;;chr2:97202480..97202499,+!p1@ARID5A!0.73!49.82!ARID5A;;chr1:3568928..3568946,+!p4@TP73!0.73!4.43!TP73;;chr11:19262461..19262476,-!p5@E2F8!0.73!4.36!E2F8;;chr15:60884706..60884743,-!p1@RORA!0.72!24.53!RORA;;chr19:926001..926046,+!p1@ARID3A!0.72!16.12!ARID3A;;chr9:2015306..2015323,+!p3@SMARCA2!0.72!12.00!SMARCA2;;chr9:1050449..1050468,+!p2@DMRT2!0.72!4.20!DMRT2;;chr12:103352326..103352351,+!p3@ASCL1!0.72!4.20!ASCL1;;chr1:8484314..8484348,-!p7@RERE!0.71!12.15!RERE;;chr15:90544532..90544563,+!p1@ZNF710!0.71!8.94!ZNF710;;chr3:141121847..141121868,+!p5@ZBTB38!0.71!6.65!ZBTB38;;chr6:106546731..106546755,+!p5@PRDM1!0.71!4.13!PRDM1;;chr9:2015335..2015370,+!p1@SMARCA2!0.70!55.71!SMARCA2;;chrX:131623044..131623089,-!p1@MBNL3!0.70!18.57!MBNL3;;chr20:44600199..44600219,-!p3@ZNF335!0.70!5.65!ZNF335;;chr19:4153613..4153652,+!p1@CREB3L3!0.70!3.97!CREB3L3;;chr3:141105235..141105307,+!p7@ZBTB38!0.70!3.97!ZBTB38;;chr14:55493763..55493824,-!p1@WDHD1!0.69!33.55!WDHD1;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.69!19.79!TAL1;;chr20:6748325..6748352,+!p1@BMP2!0.69!5.96!BMP2;;chr1:3568911..3568925,+!p9@TP73!0.69!3.90!TP73;;chr2:8822176..8822196,+!p1@ID2!0.68!611.77!ID2;;chr9:3525910..3525955,-!p4@RFX3!0.68!12.76!RFX3;;chr1:170632285..170632309,+!p1@PRRX1!0.68!4.36!PRRX1;;chr2:63277948..63277974,+!p1@OTX1!0.67!3.67!OTX1;;ch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|ffid_belonging_in_development=CL:0000134,CL:0000051
|fonse_cell_line=FF:0101035,FF:0101522
|fonse_cell_line=FF:0101035,FF:0101522
|fonse_cell_line_closure=FF:0101035,FF:0101522
|fonse_cell_line_closure=FF:0101035,FF:0101522
Line 66: Line 40:
|fonse_treatment=
|fonse_treatment=
|fonse_treatment_closure=
|fonse_treatment_closure=
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|comment=
|created_by=
|creation_date=
|def=
|has_quality=
|has_quality=
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|rna_box=111
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|rna_concentration=0.51791
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_lot_number=
|rna_od260/230=2.15
|rna_od260/280=2.09
|rna_position=C2
|rna_rin=
|rna_sample_type=total RNA
|rna_tube_id=111C2
|rna_weight_ug=25.8955
|sample_age=
|sample_category=cell lines
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|sample_cell_line=GM12878
|sample_cell_lot=
|sample_cell_type=b cell
|sample_collaboration=Carrie Davis (Cold spring Harbor Laboratories)
|sample_company=
|sample_description=
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|sample_ethnicity=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;9.51055384301511e-273!GO:0043227;membrane-bound organelle;1.44323679784905e-230!GO:0043231;intracellular membrane-bound organelle;3.93485403432379e-230!GO:0043226;organelle;9.47053580271764e-225!GO:0043229;intracellular organelle;8.06096803946486e-224!GO:0005737;cytoplasm;3.36603885511642e-169!GO:0044422;organelle part;9.60218812946568e-160!GO:0044446;intracellular organelle part;5.87829280230571e-158!GO:0005634;nucleus;2.87957628119507e-125!GO:0032991;macromolecular complex;6.38882591905859e-119!GO:0044237;cellular metabolic process;5.3217634184381e-115!GO:0044238;primary metabolic process;9.0778041611399e-113!GO:0044444;cytoplasmic part;4.71571698823081e-109!GO:0043170;macromolecule metabolic process;3.25687716433653e-107!GO:0044428;nuclear part;1.06396697626915e-101!GO:0030529;ribonucleoprotein complex;3.09360734937533e-100!GO:0003723;RNA binding;1.53208365721818e-92!GO:0043233;organelle lumen;1.28403223152642e-88!GO:0031974;membrane-enclosed lumen;1.28403223152642e-88!GO:0043283;biopolymer metabolic process;7.66125533681047e-75!GO:0005515;protein binding;1.11455372386054e-74!GO:0005739;mitochondrion;4.26651957569315e-74!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.06250255479691e-73!GO:0006396;RNA processing;7.53064152516385e-67!GO:0010467;gene expression;2.25184063375191e-66!GO:0006412;translation;1.67547207670097e-60!GO:0043234;protein complex;5.11314341557321e-60!GO:0031981;nuclear lumen;5.14011338926624e-58!GO:0005840;ribosome;1.68772672020891e-53!GO:0016071;mRNA metabolic process;3.0372059314e-53!GO:0044429;mitochondrial part;5.58254564099722e-52!GO:0006259;DNA metabolic process;1.70212229921006e-50!GO:0031967;organelle envelope;6.2194024592268e-49!GO:0031975;envelope;1.68393198016341e-48!GO:0019538;protein metabolic process;1.29310732199043e-47!GO:0003676;nucleic acid binding;1.84284310645334e-46!GO:0008380;RNA splicing;3.11532330407415e-46!GO:0003735;structural constituent of ribosome;8.73232961182088e-46!GO:0006397;mRNA processing;3.09413802174739e-45!GO:0031090;organelle membrane;2.32578726577392e-44!GO:0016043;cellular component organization and biogenesis;5.4408943742177e-44!GO:0006996;organelle organization and biogenesis;2.24502328196073e-43!GO:0044267;cellular protein metabolic process;5.56825068588039e-43!GO:0044249;cellular biosynthetic process;2.0976510520149e-42!GO:0044260;cellular macromolecule metabolic process;3.23121882793828e-42!GO:0033036;macromolecule localization;3.11419730197393e-41!GO:0009059;macromolecule biosynthetic process;7.53540405586032e-41!GO:0009058;biosynthetic process;5.14783726862044e-40!GO:0033279;ribosomal subunit;1.12536466732258e-39!GO:0015031;protein transport;3.01063977637778e-39!GO:0043228;non-membrane-bound organelle;6.99399219842862e-39!GO:0043232;intracellular non-membrane-bound organelle;6.99399219842862e-39!GO:0005829;cytosol;1.56662505938774e-38!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.22663957168769e-38!GO:0007049;cell cycle;4.37687959906397e-38!GO:0045184;establishment of protein localization;2.85923548408409e-37!GO:0008104;protein localization;8.17712874023349e-37!GO:0000166;nucleotide binding;1.02140664235753e-36!GO:0005654;nucleoplasm;2.5759372166086e-36!GO:0046907;intracellular transport;6.50640473536709e-36!GO:0016070;RNA metabolic process;1.63679385868754e-35!GO:0005681;spliceosome;4.17846782669241e-35!GO:0065003;macromolecular complex assembly;9.93291183657461e-35!GO:0006974;response to DNA damage stimulus;8.70625852245237e-32!GO:0005740;mitochondrial envelope;1.85648926868131e-31!GO:0022607;cellular component assembly;4.16747366763697e-30!GO:0006886;intracellular protein transport;5.67537362470014e-30!GO:0022402;cell cycle process;6.12963309149086e-30!GO:0019866;organelle inner membrane;1.55172221082079e-29!GO:0031966;mitochondrial membrane;1.94196161851725e-29!GO:0005694;chromosome;2.13940231939511e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.6997046326876e-28!GO:0006281;DNA repair;1.23258863993822e-27!GO:0000278;mitotic cell cycle;1.89684643067609e-27!GO:0044451;nucleoplasm part;2.13710697647611e-27!GO:0005743;mitochondrial inner membrane;4.57005069314851e-27!GO:0051649;establishment of cellular localization;1.11490325206767e-26!GO:0044427;chromosomal part;4.11549939319724e-26!GO:0051641;cellular localization;5.52940576624868e-26!GO:0044445;cytosolic part;5.9591468443807e-26!GO:0032553;ribonucleotide binding;1.06506987089911e-25!GO:0032555;purine ribonucleotide binding;1.06506987089911e-25!GO:0017076;purine nucleotide binding;1.38499535896146e-25!GO:0022403;cell cycle phase;7.97125732190651e-25!GO:0031980;mitochondrial lumen;3.51554378573645e-24!GO:0005759;mitochondrial matrix;3.51554378573645e-24!GO:0000087;M phase of mitotic cell cycle;4.88810865618873e-24!GO:0007067;mitosis;7.07548203693475e-24!GO:0016462;pyrophosphatase activity;1.3998960781603e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;2.03743745479226e-23!GO:0005730;nucleolus;2.23207531456177e-23!GO:0005524;ATP binding;2.23207531456177e-23!GO:0017111;nucleoside-triphosphatase activity;2.42786124706371e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;2.48055868389387e-23!GO:0006915;apoptosis;3.55999828939028e-23!GO:0051276;chromosome organization and biogenesis;3.70293193274465e-23!GO:0012501;programmed cell death;4.27662006554066e-23!GO:0032559;adenyl ribonucleotide binding;7.78008351384916e-23!GO:0030554;adenyl nucleotide binding;1.61531238014108e-22!GO:0051301;cell division;1.83129374959253e-22!GO:0000279;M phase;2.08314862237253e-22!GO:0044455;mitochondrial membrane part;4.3977527607197e-22!GO:0006119;oxidative phosphorylation;9.58369115898812e-22!GO:0009719;response to endogenous stimulus;3.32905237685561e-21!GO:0006260;DNA replication;7.41801732715316e-21!GO:0044265;cellular macromolecule catabolic process;9.66049254756119e-21!GO:0015935;small ribosomal subunit;1.27573939877014e-20!GO:0006512;ubiquitin cycle;2.0198789943331e-20!GO:0008219;cell death;2.08052932241266e-20!GO:0016265;death;2.08052932241266e-20!GO:0015934;large ribosomal subunit;3.37785458685382e-20!GO:0022618;protein-RNA complex assembly;5.19129959629971e-20!GO:0008134;transcription factor binding;6.18553787031853e-20!GO:0016874;ligase activity;7.82220842650087e-20!GO:0042254;ribosome biogenesis and assembly;5.94750756524921e-19!GO:0005635;nuclear envelope;6.49015727396866e-19!GO:0043285;biopolymer catabolic process;5.4320277074697e-18!GO:0016604;nuclear body;5.72433152466097e-18!GO:0012505;endomembrane system;5.82748751190242e-18!GO:0000502;proteasome complex (sensu Eukaryota);8.16045300743377e-18!GO:0009057;macromolecule catabolic process;2.5350072428252e-17!GO:0005746;mitochondrial respiratory chain;4.03478177232825e-17!GO:0000398;nuclear mRNA splicing, via spliceosome;4.66089637132528e-17!GO:0000375;RNA splicing, via transesterification reactions;4.66089637132528e-17!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.66089637132528e-17!GO:0006457;protein folding;6.16685712681285e-17!GO:0019941;modification-dependent protein catabolic process;7.69371716234008e-17!GO:0043632;modification-dependent macromolecule catabolic process;7.69371716234008e-17!GO:0031965;nuclear membrane;9.89301630868797e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;1.02851458943915e-16!GO:0044248;cellular catabolic process;1.21901547102229e-16!GO:0043412;biopolymer modification;1.53070795992469e-16!GO:0006511;ubiquitin-dependent protein catabolic process;1.87331820717418e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.42332763986137e-16!GO:0016887;ATPase activity;2.63169361106037e-16!GO:0006605;protein targeting;3.2601765494776e-16!GO:0044257;cellular protein catabolic process;3.30258034461876e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;3.83845520434781e-16!GO:0042623;ATPase activity, coupled;7.9871170683837e-16!GO:0005761;mitochondrial ribosome;8.98085123304378e-16!GO:0000313;organellar ribosome;8.98085123304378e-16!GO:0008135;translation factor activity, nucleic acid binding;9.58720498792202e-16!GO:0006323;DNA packaging;1.55821349765759e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.74212131637658e-15!GO:0003954;NADH dehydrogenase activity;1.74212131637658e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.74212131637658e-15!GO:0004386;helicase activity;2.33904337930534e-15!GO:0006913;nucleocytoplasmic transport;2.94931897819906e-15!GO:0044453;nuclear membrane part;6.21110413847631e-15!GO:0051169;nuclear transport;7.67900855832135e-15!GO:0042981;regulation of apoptosis;8.62113699814426e-15!GO:0050794;regulation of cellular process;1.09875649204966e-14!GO:0043067;regulation of programmed cell death;1.86536488679578e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.18473498123365e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.68617055611958e-14!GO:0006464;protein modification process;3.46827532581448e-14!GO:0043687;post-translational protein modification;3.97847542634403e-14!GO:0051186;cofactor metabolic process;5.26106984445496e-14!GO:0051726;regulation of cell cycle;6.29162376808773e-14!GO:0042775;organelle ATP synthesis coupled electron transport;6.61135865579152e-14!GO:0042773;ATP synthesis coupled electron transport;6.61135865579152e-14!GO:0003712;transcription cofactor activity;8.19201241581815e-14!GO:0000074;regulation of progression through cell cycle;9.87264898743175e-14!GO:0050657;nucleic acid transport;1.26201619249616e-13!GO:0051236;establishment of RNA localization;1.26201619249616e-13!GO:0050658;RNA transport;1.26201619249616e-13!GO:0006403;RNA localization;1.38139934848185e-13!GO:0030964;NADH dehydrogenase complex (quinone);1.75564457420929e-13!GO:0045271;respiratory chain complex I;1.75564457420929e-13!GO:0005747;mitochondrial respiratory chain complex I;1.75564457420929e-13!GO:0005643;nuclear pore;2.05569736838524e-13!GO:0016607;nuclear speck;3.22095867435791e-13!GO:0006364;rRNA processing;3.94454982878497e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;5.18900265698748e-13!GO:0030163;protein catabolic process;7.68920373006479e-13!GO:0006399;tRNA metabolic process;7.93524858656198e-13!GO:0016072;rRNA metabolic process;8.92555199803472e-13!GO:0000785;chromatin;1.15544083245257e-12!GO:0008026;ATP-dependent helicase activity;2.06727524259092e-12!GO:0048770;pigment granule;2.18965037065086e-12!GO:0042470;melanosome;2.18965037065086e-12!GO:0065002;intracellular protein transport across a membrane;2.47910702180483e-12!GO:0006333;chromatin assembly or disassembly;4.43388607542623e-12!GO:0006413;translational initiation;5.85546602038008e-12!GO:0003743;translation initiation factor activity;7.95753040046431e-12!GO:0051028;mRNA transport;1.05832748067684e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.06219712465722e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.14805526380056e-11!GO:0051082;unfolded protein binding;1.3042734680699e-11!GO:0006732;coenzyme metabolic process;1.33226770062853e-11!GO:0006446;regulation of translational initiation;1.75040419620273e-11!GO:0003697;single-stranded DNA binding;2.65125151103177e-11!GO:0048193;Golgi vesicle transport;2.78019951899662e-11!GO:0005783;endoplasmic reticulum;3.73760408430432e-11!GO:0019222;regulation of metabolic process;4.30945658256991e-11!GO:0016568;chromatin modification;4.69046565191745e-11!GO:0043566;structure-specific DNA binding;4.89815627233976e-11!GO:0046930;pore complex;5.57696703257743e-11!GO:0006261;DNA-dependent DNA replication;6.55360052365497e-11!GO:0016779;nucleotidyltransferase activity;9.71557673859646e-11!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.09742044992004e-10!GO:0044432;endoplasmic reticulum part;1.1202722750653e-10!GO:0065004;protein-DNA complex assembly;1.60812793943991e-10!GO:0017038;protein import;1.75542909774798e-10!GO:0051246;regulation of protein metabolic process;2.19973348636461e-10!GO:0006366;transcription from RNA polymerase II promoter;3.75668708572669e-10!GO:0000775;chromosome, pericentric region;3.89263901574127e-10!GO:0030532;small nuclear ribonucleoprotein complex;7.28671540572831e-10!GO:0008639;small protein conjugating enzyme activity;7.38295993832457e-10!GO:0009055;electron carrier activity;7.70898851125226e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;8.83498872940631e-10!GO:0004812;aminoacyl-tRNA ligase activity;8.83498872940631e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;8.83498872940631e-10!GO:0009056;catabolic process;1.07264381951656e-09!GO:0009259;ribonucleotide metabolic process;1.21243167261781e-09!GO:0004842;ubiquitin-protein ligase activity;1.22443097280714e-09!GO:0043038;amino acid activation;1.47064683572642e-09!GO:0006418;tRNA aminoacylation for protein translation;1.47064683572642e-09!GO:0043039;tRNA aminoacylation;1.47064683572642e-09!GO:0009615;response to virus;1.6168130694975e-09!GO:0019787;small conjugating protein ligase activity;1.63153958917044e-09!GO:0016740;transferase activity;1.6687184516265e-09!GO:0006163;purine nucleotide metabolic process;2.03998280383942e-09!GO:0006461;protein complex assembly;2.58350896959264e-09!GO:0050789;regulation of biological process;3.3083301519983e-09!GO:0006793;phosphorus metabolic process;3.56329567953995e-09!GO:0006796;phosphate metabolic process;3.56329567953995e-09!GO:0006164;purine nucleotide biosynthetic process;3.94634429712352e-09!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.0409645355337e-09!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;4.16335280966078e-09!GO:0003713;transcription coactivator activity;4.32795572125614e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;4.92815869447699e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;4.94834974674419e-09!GO:0009260;ribonucleotide biosynthetic process;5.63299957337353e-09!GO:0005819;spindle;5.77271205993864e-09!GO:0031323;regulation of cellular metabolic process;5.84916847459895e-09!GO:0005789;endoplasmic reticulum membrane;6.84722556270299e-09!GO:0007005;mitochondrion organization and biogenesis;6.99880489477689e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.03638342211893e-08!GO:0016787;hydrolase activity;1.37576176455985e-08!GO:0009150;purine ribonucleotide metabolic process;1.55089050821651e-08!GO:0009060;aerobic respiration;1.7934418890614e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.899534639355e-08!GO:0005839;proteasome core complex (sensu Eukaryota);2.2079861817059e-08!GO:0016563;transcription activator activity;2.34302177146111e-08!GO:0008094;DNA-dependent ATPase activity;2.42602508368868e-08!GO:0051188;cofactor biosynthetic process;2.49808950351589e-08!GO:0006916;anti-apoptosis;2.52862350074397e-08!GO:0005794;Golgi apparatus;3.01489005174979e-08!GO:0009152;purine ribonucleotide biosynthetic process;3.01489005174979e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;4.01516707628233e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.09886149328465e-08!GO:0043069;negative regulation of programmed cell death;4.46368463945953e-08!GO:0006310;DNA recombination;4.90408385998332e-08!GO:0008565;protein transporter activity;4.92769916079755e-08!GO:0043066;negative regulation of apoptosis;5.1165057699596e-08!GO:0015078;hydrogen ion transmembrane transporter activity;6.05232222527246e-08!GO:0016881;acid-amino acid ligase activity;6.45637775597678e-08!GO:0016310;phosphorylation;7.79842426127603e-08!GO:0005813;centrosome;9.35107198359006e-08!GO:0006350;transcription;1.04801258409765e-07!GO:0000245;spliceosome assembly;1.13472835352472e-07!GO:0007051;spindle organization and biogenesis;1.29292082869712e-07!GO:0004298;threonine endopeptidase activity;1.30847495831375e-07!GO:0045333;cellular respiration;1.33787747454372e-07!GO:0019829;cation-transporting ATPase activity;1.37696763529335e-07!GO:0051170;nuclear import;1.49343140305743e-07!GO:0005657;replication fork;1.82108102208721e-07!GO:0051168;nuclear export;1.827851069825e-07!GO:0015630;microtubule cytoskeleton;1.83268375205688e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.02246686267146e-07!GO:0005815;microtubule organizing center;2.05862535399154e-07!GO:0016192;vesicle-mediated transport;2.1614269012385e-07!GO:0015986;ATP synthesis coupled proton transport;2.66726314499961e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.66726314499961e-07!GO:0009108;coenzyme biosynthetic process;2.81224928948537e-07!GO:0006099;tricarboxylic acid cycle;2.95061131165406e-07!GO:0046356;acetyl-CoA catabolic process;2.95061131165406e-07!GO:0006401;RNA catabolic process;3.06241087604945e-07!GO:0006606;protein import into nucleus;3.38998867460323e-07!GO:0043065;positive regulation of apoptosis;3.58060227434861e-07!GO:0031202;RNA splicing factor activity, transesterification mechanism;4.42486683436172e-07!GO:0007059;chromosome segregation;4.63729313441114e-07!GO:0006888;ER to Golgi vesicle-mediated transport;5.21550705094003e-07!GO:0043068;positive regulation of programmed cell death;5.6221919562909e-07!GO:0045259;proton-transporting ATP synthase complex;5.9829269841939e-07!GO:0006334;nucleosome assembly;6.03715735663673e-07!GO:0006084;acetyl-CoA metabolic process;6.30665418821085e-07!GO:0000075;cell cycle checkpoint;6.70317772616685e-07!GO:0031497;chromatin assembly;7.2941294309836e-07!GO:0032446;protein modification by small protein conjugation;7.53789786296844e-07!GO:0010468;regulation of gene expression;8.74371429834187e-07!GO:0009117;nucleotide metabolic process;8.84571068683997e-07!GO:0030120;vesicle coat;9.88966168916157e-07!GO:0030662;coated vesicle membrane;9.88966168916157e-07!GO:0006917;induction of apoptosis;1.03252095137808e-06!GO:0048523;negative regulation of cellular process;1.27338970537599e-06!GO:0051187;cofactor catabolic process;1.41628601330687e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.44181075746299e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.44181075746299e-06!GO:0006302;double-strand break repair;1.5460991280797e-06!GO:0007088;regulation of mitosis;1.54778065107458e-06!GO:0003724;RNA helicase activity;1.55222932017388e-06!GO:0003899;DNA-directed RNA polymerase activity;1.57537533572215e-06!GO:0016567;protein ubiquitination;1.59129695186806e-06!GO:0051325;interphase;1.60285450019548e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.62296874844179e-06!GO:0048475;coated membrane;1.65657538069825e-06!GO:0030117;membrane coat;1.65657538069825e-06!GO:0012502;induction of programmed cell death;1.67769018965223e-06!GO:0009141;nucleoside triphosphate metabolic process;1.74485639173565e-06!GO:0007243;protein kinase cascade;2.00343812247037e-06!GO:0051329;interphase of mitotic cell cycle;2.14030101807331e-06!GO:0006754;ATP biosynthetic process;2.30306984877549e-06!GO:0006753;nucleoside phosphate metabolic process;2.30306984877549e-06!GO:0016469;proton-transporting two-sector ATPase complex;2.39455952240736e-06!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.55127194794435e-06!GO:0016363;nuclear matrix;2.73296652318573e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.79683439023209e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.79683439023209e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.04848414253962e-06!GO:0009144;purine nucleoside triphosphate metabolic process;3.04848414253962e-06!GO:0005768;endosome;3.08387788314852e-06!GO:0046034;ATP metabolic process;3.72917764146083e-06!GO:0019899;enzyme binding;3.73169293540213e-06!GO:0009109;coenzyme catabolic process;4.01749204858436e-06!GO:0006402;mRNA catabolic process;4.02206168745889e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.41120657197326e-06!GO:0006752;group transfer coenzyme metabolic process;7.58606615676388e-06!GO:0005793;ER-Golgi intermediate compartment;7.98365326991291e-06!GO:0000776;kinetochore;8.33581691813003e-06!GO:0048522;positive regulation of cellular process;9.07003726111522e-06!GO:0006417;regulation of translation;1.03056750730343e-05!GO:0006613;cotranslational protein targeting to membrane;1.06339483447694e-05!GO:0003924;GTPase activity;1.23567828353659e-05!GO:0005525;GTP binding;1.26728253527937e-05!GO:0005770;late endosome;1.4430376471054e-05!GO:0043623;cellular protein complex assembly;1.44323068316648e-05!GO:0004527;exonuclease activity;1.99387140124937e-05!GO:0003690;double-stranded DNA binding;2.0124563092842e-05!GO:0051052;regulation of DNA metabolic process;2.17677455343364e-05!GO:0048519;negative regulation of biological process;2.34546850628245e-05!GO:0044452;nucleolar part;2.52240345578964e-05!GO:0032774;RNA biosynthetic process;2.70839168619381e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;2.7376450620109e-05!GO:0016741;transferase activity, transferring one-carbon groups;2.74949944096892e-05!GO:0004518;nuclease activity;2.91369137104185e-05!GO:0005762;mitochondrial large ribosomal subunit;2.99786658230558e-05!GO:0000315;organellar large ribosomal subunit;2.99786658230558e-05!GO:0051427;hormone receptor binding;3.06049252494059e-05!GO:0006839;mitochondrial transport;3.14702224663954e-05!GO:0000314;organellar small ribosomal subunit;3.14702224663954e-05!GO:0005763;mitochondrial small ribosomal subunit;3.14702224663954e-05!GO:0009165;nucleotide biosynthetic process;3.19043120011273e-05!GO:0006351;transcription, DNA-dependent;3.45002005142344e-05!GO:0003677;DNA binding;3.6223427004683e-05!GO:0003684;damaged DNA binding;3.63550828225316e-05!GO:0007093;mitotic cell cycle checkpoint;4.09325210767924e-05!GO:0003678;DNA helicase activity;4.10602578202355e-05!GO:0065007;biological regulation;4.12939123595186e-05!GO:0051252;regulation of RNA metabolic process;4.26635108723624e-05!GO:0043021;ribonucleoprotein binding;4.73036073404728e-05!GO:0008168;methyltransferase activity;4.74227609134388e-05!GO:0045786;negative regulation of progression through cell cycle;5.19080497470441e-05!GO:0035257;nuclear hormone receptor binding;6.28410641392649e-05!GO:0000151;ubiquitin ligase complex;7.12644464599802e-05!GO:0005667;transcription factor complex;7.20279857998556e-05!GO:0005798;Golgi-associated vesicle;7.91476800705585e-05!GO:0003729;mRNA binding;8.00466184383756e-05!GO:0031324;negative regulation of cellular metabolic process;8.6942558414653e-05!GO:0016564;transcription repressor activity;8.79035605175753e-05!GO:0008186;RNA-dependent ATPase activity;9.09947797636985e-05!GO:0007006;mitochondrial membrane organization and biogenesis;0.000102237924214537!GO:0008033;tRNA processing;0.00010417537007108!GO:0003714;transcription corepressor activity;0.000115814403975986!GO:0045449;regulation of transcription;0.000124654278312346!GO:0032561;guanyl ribonucleotide binding;0.000125229812388369!GO:0019001;guanyl nucleotide binding;0.000125229812388369!GO:0031326;regulation of cellular biosynthetic process;0.000135477745833125!GO:0003682;chromatin binding;0.000144258489930375!GO:0016251;general RNA polymerase II transcription factor activity;0.000156282348293337!GO:0065009;regulation of a molecular function;0.000163929539688203!GO:0008632;apoptotic program;0.000166010737731117!GO:0043681;protein import into mitochondrion;0.000179563831577183!GO:0044440;endosomal part;0.000183944873491767!GO:0010008;endosome membrane;0.000183944873491767!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000185897833522148!GO:0006950;response to stress;0.00018734433117352!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000192408366570089!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000210201547239958!GO:0030658;transport vesicle membrane;0.000214372910581438!GO:0005885;Arp2/3 protein complex;0.000215035571735563!GO:0006626;protein targeting to mitochondrion;0.000217488952764138!GO:0004674;protein serine/threonine kinase activity;0.000221532126619759!GO:0006383;transcription from RNA polymerase III promoter;0.000236434191489422!GO:0005741;mitochondrial outer membrane;0.000256848341282365!GO:0005048;signal sequence binding;0.000266470046566809!GO:0004004;ATP-dependent RNA helicase activity;0.000276443730253269!GO:0006352;transcription initiation;0.000282930483005044!GO:0030880;RNA polymerase complex;0.000288775353914536!GO:0006612;protein targeting to membrane;0.000299476709649145!GO:0000786;nucleosome;0.000299476709649145!GO:0031072;heat shock protein binding;0.000301918368976997!GO:0031968;organelle outer membrane;0.00030594440656655!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000325444793971044!GO:0006414;translational elongation;0.000331285868815931!GO:0043488;regulation of mRNA stability;0.000355244660871407!GO:0043487;regulation of RNA stability;0.000355244660871407!GO:0007052;mitotic spindle organization and biogenesis;0.000358195048658081!GO:0016853;isomerase activity;0.000362308409365409!GO:0019867;outer membrane;0.000373194007484196!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000404446678653517!GO:0048471;perinuclear region of cytoplasm;0.000407517057669772!GO:0032508;DNA duplex unwinding;0.000435333090014058!GO:0032392;DNA geometric change;0.000435333090014058!GO:0005684;U2-dependent spliceosome;0.000447699322145757!GO:0009967;positive regulation of signal transduction;0.000451324803071528!GO:0000228;nuclear chromosome;0.000463102135710387!GO:0007010;cytoskeleton organization and biogenesis;0.000468286187824612!GO:0006611;protein export from nucleus;0.000471996842850706!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00050102605179103!GO:0015399;primary active transmembrane transporter activity;0.00050102605179103!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000512081784711229!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000526648526356563!GO:0044431;Golgi apparatus part;0.000530496987930367!GO:0048518;positive regulation of biological process;0.00054238774594461!GO:0006405;RNA export from nucleus;0.000583095175893276!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00058309613097067!GO:0000428;DNA-directed RNA polymerase complex;0.00058309613097067!GO:0032200;telomere organization and biogenesis;0.00068551172513902!GO:0000723;telomere maintenance;0.00068551172513902!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.000691267739515805!GO:0046483;heterocycle metabolic process;0.000698242610188828!GO:0006268;DNA unwinding during replication;0.000703466337912545!GO:0030660;Golgi-associated vesicle membrane;0.000745088342253783!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000785316061524372!GO:0009892;negative regulation of metabolic process;0.000907205572139179!GO:0031970;organelle envelope lumen;0.000922414198791848!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.00103255805060642!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00105042917160413!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00105042917160413!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00105042917160413!GO:0048500;signal recognition particle;0.0010943823081886!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00112406564458619!GO:0009889;regulation of biosynthetic process;0.00120417074841943!GO:0043596;nuclear replication fork;0.00142270067660065!GO:0006270;DNA replication initiation;0.0014253326034995!GO:0000059;protein import into nucleus, docking;0.0014285999137737!GO:0004532;exoribonuclease activity;0.00142877611469092!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00142877611469092!GO:0005758;mitochondrial intermembrane space;0.00144335302941881!GO:0042770;DNA damage response, signal transduction;0.00146828177512071!GO:0047485;protein N-terminus binding;0.00149450416972567!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00152851302868228!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00152851302868228!GO:0008139;nuclear localization sequence binding;0.00153409992610523!GO:0048468;cell development;0.00158604872922956!GO:0005637;nuclear inner membrane;0.00163542188044797!GO:0016491;oxidoreductase activity;0.00165662268132669!GO:0000323;lytic vacuole;0.00165662268132669!GO:0005764;lysosome;0.00165662268132669!GO:0003725;double-stranded RNA binding;0.00165788270538022!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00166906667416243!GO:0005876;spindle microtubule;0.00168307750218709!GO:0000819;sister chromatid segregation;0.00170802793304663!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00170848260555344!GO:0004003;ATP-dependent DNA helicase activity;0.00170920707046858!GO:0006520;amino acid metabolic process;0.00175242308015223!GO:0046822;regulation of nucleocytoplasmic transport;0.00176337765364095!GO:0000082;G1/S transition of mitotic cell cycle;0.0018396631685406!GO:0005769;early endosome;0.00185472081868261!GO:0006355;regulation of transcription, DNA-dependent;0.00185488133620852!GO:0000049;tRNA binding;0.00187082710305816!GO:0006891;intra-Golgi vesicle-mediated transport;0.00196000126516073!GO:0016859;cis-trans isomerase activity;0.00198135254021431!GO:0000922;spindle pole;0.00204733957690249!GO:0006289;nucleotide-excision repair;0.00207709865662634!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00209598431104858!GO:0000070;mitotic sister chromatid segregation;0.00209766139793899!GO:0031124;mRNA 3'-end processing;0.00211606064356632!GO:0006091;generation of precursor metabolites and energy;0.00212915570021272!GO:0033673;negative regulation of kinase activity;0.00214518483343595!GO:0006469;negative regulation of protein kinase activity;0.00214518483343595!GO:0051920;peroxiredoxin activity;0.00216833107868582!GO:0000725;recombinational repair;0.00219695515695132!GO:0000724;double-strand break repair via homologous recombination;0.00219695515695132!GO:0006338;chromatin remodeling;0.00219823881394813!GO:0051348;negative regulation of transferase activity;0.0022224674506937!GO:0051223;regulation of protein transport;0.00223865242022381!GO:0005773;vacuole;0.00225383500336037!GO:0008312;7S RNA binding;0.00226443416562226!GO:0008408;3'-5' exonuclease activity;0.00228439574130444!GO:0045454;cell redox homeostasis;0.00229439476091874!GO:0016481;negative regulation of transcription;0.00254089725724511!GO:0007242;intracellular signaling cascade;0.00254590224022129!GO:0003711;transcription elongation regulator activity;0.00269237673579988!GO:0006595;polyamine metabolic process;0.00271902478502102!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00287766841059624!GO:0018193;peptidyl-amino acid modification;0.00291472633064783!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00295054203307717!GO:0045047;protein targeting to ER;0.00295054203307717!GO:0022890;inorganic cation transmembrane transporter activity;0.00295360832043944!GO:0009451;RNA modification;0.0029727605094186!GO:0009124;nucleoside monophosphate biosynthetic process;0.00304672619523793!GO:0009123;nucleoside monophosphate metabolic process;0.00304672619523793!GO:0016126;sterol biosynthetic process;0.00307505442123046!GO:0019752;carboxylic acid metabolic process;0.00307505442123046!GO:0051539;4 iron, 4 sulfur cluster binding;0.00308163303606509!GO:0030867;rough endoplasmic reticulum membrane;0.0030828987225568!GO:0006284;base-excision repair;0.00309982176135968!GO:0051789;response to protein stimulus;0.00309982176135968!GO:0006986;response to unfolded protein;0.00309982176135968!GO:0045941;positive regulation of transcription;0.00311568587047261!GO:0000793;condensed chromosome;0.00318729472025197!GO:0000781;chromosome, telomeric region;0.00322121340713876!GO:0016791;phosphoric monoester hydrolase activity;0.00323547056685475!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00330447457340955!GO:0008654;phospholipid biosynthetic process;0.00342162749881395!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00349522710849917!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00349569922779873!GO:0007017;microtubule-based process;0.00368689815207707!GO:0006007;glucose catabolic process;0.00371593460485712!GO:0006082;organic acid metabolic process;0.00381415577166672!GO:0006818;hydrogen transport;0.00387779187356554!GO:0016584;nucleosome positioning;0.00393044404989335!GO:0030134;ER to Golgi transport vesicle;0.00403223656685326!GO:0015631;tubulin binding;0.004074852030033!GO:0030127;COPII vesicle coat;0.00424180437916855!GO:0012507;ER to Golgi transport vesicle membrane;0.00424180437916855!GO:0042393;histone binding;0.00424434595175777!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00424434595175777!GO:0030521;androgen receptor signaling pathway;0.00424871901861221!GO:0030518;steroid hormone receptor signaling pathway;0.00457703228219404!GO:0032259;methylation;0.00460727322313101!GO:0015992;proton transport;0.00463816330467186!GO:0035258;steroid hormone receptor binding;0.00477963551334095!GO:0008022;protein C-terminus binding;0.00478737651811974!GO:0009112;nucleobase metabolic process;0.00480806250810123!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00480806250810123!GO:0015002;heme-copper terminal oxidase activity;0.00480806250810123!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00480806250810123!GO:0004129;cytochrome-c oxidase activity;0.00480806250810123!GO:0000139;Golgi membrane;0.00487754443156749!GO:0043492;ATPase activity, coupled to movement of substances;0.00490843862064141!GO:0046966;thyroid hormone receptor binding;0.00493753346249597!GO:0003702;RNA polymerase II transcription factor activity;0.0050210272231353!GO:0008047;enzyme activator activity;0.00505233160824447!GO:0016197;endosome transport;0.0050566801370485!GO:0008637;apoptotic mitochondrial changes;0.00525119846411029!GO:0000178;exosome (RNase complex);0.00533645131388046!GO:0030118;clathrin coat;0.00547257665302654!GO:0022415;viral reproductive process;0.0055194193316015!GO:0009116;nucleoside metabolic process;0.00552227932176971!GO:0007264;small GTPase mediated signal transduction;0.00560092266222557!GO:0006144;purine base metabolic process;0.00562429799543534!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00566031104809259!GO:0008234;cysteine-type peptidase activity;0.00592113339486638!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00598870997889635!GO:0030384;phosphoinositide metabolic process;0.00604633659837925!GO:0006275;regulation of DNA replication;0.00610201191575043!GO:0008629;induction of apoptosis by intracellular signals;0.00612286488440353!GO:0031123;RNA 3'-end processing;0.00612286488440353!GO:0046649;lymphocyte activation;0.00630290435599081!GO:0000339;RNA cap binding;0.00630299736935228!GO:0006695;cholesterol biosynthetic process;0.00635311495950727!GO:0000209;protein polyubiquitination;0.00650128012291556!GO:0043601;nuclear replisome;0.00650128012291556!GO:0030894;replisome;0.00650128012291556!GO:0042113;B cell activation;0.00651683111835804!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00668897144581415!GO:0031252;leading edge;0.00671512634097385!GO:0043022;ribosome binding;0.00675495261392871!GO:0009161;ribonucleoside monophosphate metabolic process;0.00680534515027446!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00680534515027446!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00706353140352557!GO:0003887;DNA-directed DNA polymerase activity;0.00715460710966004!GO:0045893;positive regulation of transcription, DNA-dependent;0.00732521948494186!GO:0005669;transcription factor TFIID complex;0.00769015991168703!GO:0000175;3'-5'-exoribonuclease activity;0.00791646681641678!GO:0044454;nuclear chromosome part;0.00816531049227926!GO:0030133;transport vesicle;0.00837137858043725!GO:0006376;mRNA splice site selection;0.00839031457045679!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00839031457045679!GO:0042802;identical protein binding;0.00850915785876183!GO:0042613;MHC class II protein complex;0.00850915785876183!GO:0015980;energy derivation by oxidation of organic compounds;0.00853721278604862!GO:0000152;nuclear ubiquitin ligase complex;0.008549233525675!GO:0008624;induction of apoptosis by extracellular signals;0.008549233525675!GO:0051092;activation of NF-kappaB transcription factor;0.00872891129646262!GO:0005663;DNA replication factor C complex;0.00894467859891694!GO:0003746;translation elongation factor activity;0.00913041015547517!GO:0006650;glycerophospholipid metabolic process;0.00920564262760696!GO:0022411;cellular component disassembly;0.00932853948202739!GO:0051087;chaperone binding;0.0095652918865619!GO:0016788;hydrolase activity, acting on ester bonds;0.00959086172232044!GO:0051098;regulation of binding;0.00965442248378676!GO:0044450;microtubule organizing center part;0.0096793945499274!GO:0000910;cytokinesis;0.00969385696135079!GO:0005832;chaperonin-containing T-complex;0.00971255185191154!GO:0030036;actin cytoskeleton organization and biogenesis;0.00971771398470054!GO:0033367;protein localization in mast cell secretory granule;0.00971771398470054!GO:0033365;protein localization in organelle;0.00971771398470054!GO:0033371;T cell secretory granule organization and biogenesis;0.00971771398470054!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.00971771398470054!GO:0033375;protease localization in T cell secretory granule;0.00971771398470054!GO:0042629;mast cell granule;0.00971771398470054!GO:0033377;maintenance of protein localization in T cell secretory granule;0.00971771398470054!GO:0033364;mast cell secretory granule organization and biogenesis;0.00971771398470054!GO:0033380;granzyme B localization in T cell secretory granule;0.00971771398470054!GO:0033379;maintenance of protease localization in T cell secretory granule;0.00971771398470054!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.00971771398470054!GO:0033368;protease localization in mast cell secretory granule;0.00971771398470054!GO:0033366;protein localization in secretory granule;0.00971771398470054!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.00971771398470054!GO:0033374;protein localization in T cell secretory granule;0.00971771398470054!GO:0051053;negative regulation of DNA metabolic process;0.00985849249910858!GO:0031902;late endosome membrane;0.0107044894198613!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0116131353879633!GO:0000726;non-recombinational repair;0.0117697196491305!GO:0030663;COPI coated vesicle membrane;0.0122329738971591!GO:0030126;COPI vesicle coat;0.0122329738971591!GO:0009303;rRNA transcription;0.0122329738971591!GO:0043414;biopolymer methylation;0.0122877244894941!GO:0050662;coenzyme binding;0.0124580236932131!GO:0009893;positive regulation of metabolic process;0.0126780250362966!GO:0007265;Ras protein signal transduction;0.0127688537362428!GO:0016272;prefoldin complex;0.0128404671098852!GO:0008276;protein methyltransferase activity;0.0129243458916827!GO:0006378;mRNA polyadenylation;0.0131534026186339!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0133187418384363!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0133772616542501!GO:0004721;phosphoprotein phosphatase activity;0.0133996402574678!GO:0007004;telomere maintenance via telomerase;0.0137468776323664!GO:0050851;antigen receptor-mediated signaling pathway;0.0139651338570101!GO:0050790;regulation of catalytic activity;0.0140603274455459!GO:0008250;oligosaccharyl transferase complex;0.0141245187307664!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0141803026964339!GO:0046489;phosphoinositide biosynthetic process;0.0142134644244221!GO:0005850;eukaryotic translation initiation factor 2 complex;0.014385951049219!GO:0031577;spindle checkpoint;0.0148506455955374!GO:0043621;protein self-association;0.0151259500668535!GO:0006096;glycolysis;0.0153462305863863!GO:0004576;oligosaccharyl transferase activity;0.0153973767934128!GO:0031625;ubiquitin protein ligase binding;0.0156569754710524!GO:0016301;kinase activity;0.0158866442630316!GO:0007050;cell cycle arrest;0.015926426924151!GO:0033116;ER-Golgi intermediate compartment membrane;0.0162014129147553!GO:0016311;dephosphorylation;0.0165750873385674!GO:0006400;tRNA modification;0.0166105949210521!GO:0051540;metal cluster binding;0.0168153351302541!GO:0051536;iron-sulfur cluster binding;0.0168153351302541!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0169320837513375!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0169320837513375!GO:0009126;purine nucleoside monophosphate metabolic process;0.0169320837513375!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0169320837513375!GO:0000118;histone deacetylase complex;0.0169649105918307!GO:0051090;regulation of transcription factor activity;0.0169935244246006!GO:0016407;acetyltransferase activity;0.0171033156603212!GO:0051101;regulation of DNA binding;0.0174896754544458!GO:0030137;COPI-coated vesicle;0.0175505556031629!GO:0030695;GTPase regulator activity;0.0178443969315997!GO:0016605;PML body;0.017954216122332!GO:0000287;magnesium ion binding;0.0180339237189308!GO:0046365;monosaccharide catabolic process;0.0184513477348809!GO:0045045;secretory pathway;0.0196112617565605!GO:0008180;signalosome;0.0196864072269766!GO:0046112;nucleobase biosynthetic process;0.0198354909651538!GO:0004536;deoxyribonuclease activity;0.0198775166162799!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0200235303859727!GO:0019783;small conjugating protein-specific protease activity;0.0203877046069989!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0204286207726983!GO:0001824;blastocyst development;0.020444918762188!GO:0005788;endoplasmic reticulum lumen;0.0210281733885124!GO:0005096;GTPase activator activity;0.021051042758751!GO:0008538;proteasome activator activity;0.021051042758751!GO:0031325;positive regulation of cellular metabolic process;0.02160878713847!GO:0030125;clathrin vesicle coat;0.0217014725687706!GO:0030665;clathrin coated vesicle membrane;0.0217014725687706!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0218263323631041!GO:0051656;establishment of organelle localization;0.0222396047429567!GO:0000738;DNA catabolic process, exonucleolytic;0.0223105707629297!GO:0006278;RNA-dependent DNA replication;0.0225965761236504!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.022770679248985!GO:0004843;ubiquitin-specific protease activity;0.0233185391261995!GO:0048487;beta-tubulin binding;0.0235219296118041!GO:0032984;macromolecular complex disassembly;0.0235898676114431!GO:0032940;secretion by cell;0.0236330073419891!GO:0051235;maintenance of localization;0.0243068125429697!GO:0030433;ER-associated protein catabolic process;0.0248251942833486!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0248251942833486!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0248929993686902!GO:0006767;water-soluble vitamin metabolic process;0.0251859258701863!GO:0006406;mRNA export from nucleus;0.0258249842530168!GO:0004177;aminopeptidase activity;0.0260954598229831!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.026199706707739!GO:0000119;mediator complex;0.0263385098878807!GO:0019843;rRNA binding;0.0263732125726726!GO:0046474;glycerophospholipid biosynthetic process;0.0266637899644969!GO:0008097;5S rRNA binding;0.0267904375179949!GO:0004540;ribonuclease activity;0.0267904375179949!GO:0045321;leukocyte activation;0.0268150896380453!GO:0000018;regulation of DNA recombination;0.026823853655809!GO:0005092;GDP-dissociation inhibitor activity;0.0270737849114888!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0271628673713067!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0271628673713067!GO:0030522;intracellular receptor-mediated signaling pathway;0.0276267191268177!GO:0031988;membrane-bound vesicle;0.0279667926676989!GO:0030262;apoptotic nuclear changes;0.0282982719971787!GO:0004448;isocitrate dehydrogenase activity;0.0288796570621648!GO:0006596;polyamine biosynthetic process;0.0290083032152667!GO:0000792;heterochromatin;0.0290635962712323!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0291143418540204!GO:0006308;DNA catabolic process;0.0291310975769153!GO:0019320;hexose catabolic process;0.029185161685745!GO:0044438;microbody part;0.0293390044287116!GO:0044439;peroxisomal part;0.0293390044287116!GO:0006730;one-carbon compound metabolic process;0.02960293631023!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0296759843962827!GO:0019904;protein domain specific binding;0.0301302048091531!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0309304700923471!GO:0043284;biopolymer biosynthetic process;0.0310755092341404!GO:0051338;regulation of transferase activity;0.0310910134867644!GO:0046164;alcohol catabolic process;0.0310910134867644!GO:0000096;sulfur amino acid metabolic process;0.0310910134867644!GO:0043624;cellular protein complex disassembly;0.0312238767691606!GO:0033170;DNA-protein loading ATPase activity;0.0313074384723581!GO:0003689;DNA clamp loader activity;0.0313074384723581!GO:0008017;microtubule binding;0.031628058520549!GO:0045892;negative regulation of transcription, DNA-dependent;0.0317022881541427!GO:0005083;small GTPase regulator activity;0.0317684970041145!GO:0030029;actin filament-based process;0.031909810968948!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0327430441382127!GO:0032039;integrator complex;0.0327780853137516!GO:0018196;peptidyl-asparagine modification;0.0330124253208123!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0330124253208123!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0331021536647442!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0331021536647442!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0331021536647442!GO:0031570;DNA integrity checkpoint;0.0333586199824589!GO:0046426;negative regulation of JAK-STAT cascade;0.0333673917156014!GO:0051881;regulation of mitochondrial membrane potential;0.0336987448258339!GO:0043241;protein complex disassembly;0.0337937030762003!GO:0001891;phagocytic cup;0.034831896245977!GO:0004221;ubiquitin thiolesterase activity;0.035007750362918!GO:0008156;negative regulation of DNA replication;0.0356295461167888!GO:0005874;microtubule;0.0356680958154709!GO:0019079;viral genome replication;0.0357568286574939!GO:0031371;ubiquitin conjugating enzyme complex;0.0363324583462364!GO:0009081;branched chain family amino acid metabolic process;0.0364805677883496!GO:0006519;amino acid and derivative metabolic process;0.0366334058300788!GO:0043549;regulation of kinase activity;0.0367216450091648!GO:0050178;phenylpyruvate tautomerase activity;0.037147702722673!GO:0035267;NuA4 histone acetyltransferase complex;0.0377113257829265!GO:0045069;regulation of viral genome replication;0.0377917259226831!GO:0030140;trans-Golgi network transport vesicle;0.0382719447037851!GO:0032404;mismatch repair complex binding;0.038735921620907!GO:0046128;purine ribonucleoside metabolic process;0.038735921620907!GO:0042278;purine nucleoside metabolic process;0.038735921620907!GO:0043130;ubiquitin binding;0.0389738283235746!GO:0032182;small conjugating protein binding;0.0389738283235746!GO:0008320;protein transmembrane transporter activity;0.0390073640042113!GO:0008537;proteasome activator complex;0.0398581193145053!GO:0031647;regulation of protein stability;0.0398581193145053!GO:0006672;ceramide metabolic process;0.0398581193145053!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0398581193145053!GO:0045039;protein import into mitochondrial inner membrane;0.0398581193145053!GO:0022884;macromolecule transmembrane transporter activity;0.0406670677775282!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0406670677775282!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0407086625154636!GO:0012510;trans-Golgi network transport vesicle membrane;0.0407086625154636!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0409063017444022!GO:0003727;single-stranded RNA binding;0.0409124860597963!GO:0005652;nuclear lamina;0.0415815752128064!GO:0006984;ER-nuclear signaling pathway;0.0419847475751439!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0419915519476617!GO:0008630;DNA damage response, signal transduction resulting in induction of apoptosis;0.0423403898159849!GO:0008270;zinc ion binding;0.0424429099670923!GO:0005732;small nucleolar ribonucleoprotein complex;0.0428600228820246!GO:0050852;T cell receptor signaling pathway;0.0429961543766842!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0429961543766842!GO:0030119;AP-type membrane coat adaptor complex;0.043584371538088!GO:0000086;G2/M transition of mitotic cell cycle;0.0439934146337758!GO:0031903;microbody membrane;0.0439934146337758!GO:0005778;peroxisomal membrane;0.0439934146337758!GO:0060090;molecular adaptor activity;0.0440140222445387!GO:0006769;nicotinamide metabolic process;0.0440140222445387!GO:0005869;dynactin complex;0.0440145867921362!GO:0006470;protein amino acid dephosphorylation;0.0442683524252449!GO:0005689;U12-dependent spliceosome;0.0446812532663185!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0446919962110567!GO:0000123;histone acetyltransferase complex;0.0448637335084678!GO:0045603;positive regulation of endothelial cell differentiation;0.0453674698018589!GO:0006354;RNA elongation;0.0453723139340798!GO:0046519;sphingoid metabolic process;0.0455060555212994!GO:0030508;thiol-disulfide exchange intermediate activity;0.0458961071061759!GO:0006733;oxidoreduction coenzyme metabolic process;0.0461030286984813!GO:0043189;H4/H2A histone acetyltransferase complex;0.0461370716140173!GO:0043407;negative regulation of MAP kinase activity;0.0464736045991258!GO:0004402;histone acetyltransferase activity;0.0464753496042023!GO:0004468;lysine N-acetyltransferase activity;0.0464753496042023!GO:0006301;postreplication repair;0.0464964264754292!GO:0042026;protein refolding;0.0467664666679956!GO:0006740;NADPH regeneration;0.0471697116136828!GO:0006098;pentose-phosphate shunt;0.0471697116136828!GO:0005680;anaphase-promoting complex;0.0473588551343721!GO:0043086;negative regulation of catalytic activity;0.047467220112909!GO:0006778;porphyrin metabolic process;0.0475865913403087!GO:0033013;tetrapyrrole metabolic process;0.0475865913403087!GO:0005784;translocon complex;0.0477195780028475!GO:0005774;vacuolar membrane;0.0488452442020928!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0488452442020928!GO:0044262;cellular carbohydrate metabolic process;0.0491622397211499!GO:0032405;MutLalpha complex binding;0.0495658234843411
|sample_id=10821
|sample_note=
|sample_sex=female
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_tissue=blood
|top_motifs=POU2F1..3:2.30151557705;POU5F1:2.08364093128;HOXA9_MEIS1:2.06617446378;NFKB1_REL_RELA:2.0340936833;DMAP1_NCOR{1,2}_SMARC:1.70464573613;PDX1:1.69355208802;IRF7:1.67991945549;IRF1,2:1.6196388775;PAX6:1.57402117811;E2F1..5:1.53446764797;NKX6-1,2:1.53154601421;AIRE:1.51465808484;ELF1,2,4:1.50710963976;MYB:1.48905260263;NFY{A,B,C}:1.48336843295;ELK1,4_GABP{A,B1}:1.34867326674;TOPORS:1.27079193931;CDX1,2,4:1.13718769767;HIF1A:1.13623365786;PITX1..3:1.12516246202;SPI1:1.07811162702;VSX1,2:1.070601403;RUNX1..3:0.980259531774;YY1:0.942545669821;ZBTB16:0.901702908948;POU1F1:0.883937761127;PAX3,7:0.861090476292;NRF1:0.774683264693;PAX8:0.768294912388;SPIB:0.768230873271;FOXA2:0.724142650619;ETS1,2:0.664944692958;ZNF143:0.586215781571;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.585562794916;EVI1:0.578430036395;OCT4_SOX2{dimer}:0.554074360956;RBPJ:0.541149596199;HNF4A_NR2F1,2:0.526739444156;FOXP3:0.522244147746;SNAI1..3:0.502796939496;FOXP1:0.479760379221;BREu{core}:0.475471649427;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.472881350211;ARID5B:0.468335967531;AHR_ARNT_ARNT2:0.442689712997;FOXN1:0.4405823606;MYOD1:0.436124137492;ALX4:0.424872813296;ZEB1:0.403645049921;NKX2-2,8:0.367941917711;NANOG{mouse}:0.356377366885;LMO2:0.346638777371;NR5A1,2:0.344499435505;STAT1,3:0.343652664638;PBX1:0.339155060758;ZNF384:0.334118016244;SPZ1:0.314033597378;POU3F1..4:0.301972098291;HNF1A:0.29621437774;GATA6:0.244537558382;RXRA_VDR{dimer}:0.236086650012;RORA:0.232714646463;GFI1:0.224057909468;CUX2:0.198479889538;HSF1,2:0.197615773009;FOX{F1,F2,J1}:0.191726494907;ESR1:0.188662325952;ATF5_CREB3:0.185569001183;IKZF2:0.183722014627;TGIF1:0.138173642429;TP53:0.13021298251;EBF1:0.121386568656;CDC5L:0.106128301597;ESRRA:0.101613140083;CREB1:0.0896045000858;HES1:0.0790943881655;RFX2..5_RFXANK_RFXAP:0.0326650040205;TFDP1:0.0145694492496;SOX5:-0.0265882525833;SOX{8,9,10}:-0.0294776398203;PAX2:-0.0356487698104;LHX3,4:-0.0417503843582;PRRX1,2:-0.0681851622582;bHLH_family:-0.115516657894;ATF4:-0.12116720333;NR1H4:-0.125219120682;NKX3-2:-0.134004680258;PAX4:-0.156443817348;CRX:-0.205075583584;PRDM1:-0.218037378707;NR6A1:-0.223049847615;NFE2:-0.232195771397;ALX1:-0.234018929626;SRF:-0.267290224842;HAND1,2:-0.283276404507;BPTF:-0.28468904759;MEF2{A,B,C,D}:-0.289888039005;EP300:-0.310243006221;RXR{A,B,G}:-0.320370415891;NKX2-3_NKX2-5:-0.399969123918;DBP:-0.428377599631;UFEwm:-0.430433488557;TLX2:-0.443090630619;HOX{A4,D4}:-0.465681985865;FOS_FOS{B,L1}_JUN{B,D}:-0.480528799383;ONECUT1,2:-0.506359955562;TEF:-0.515511148284;LEF1_TCF7_TCF7L1,2:-0.52166756755;ADNP_IRX_SIX_ZHX:-0.531753320036;FOXQ1:-0.532288097387;NFATC1..3:-0.53628763459;TFAP4:-0.536491315694;HOX{A5,B5}:-0.53838924486;GATA4:-0.539013623059;HMGA1,2:-0.547454163184;PPARG:-0.568593074161;HBP1_HMGB_SSRP1_UBTF:-0.577045631779;FOSL2:-0.595046171828;BACH2:-0.609655457976;GLI1..3:-0.625037125398;KLF4:-0.625935981699;SOX17:-0.631505684351;GFI1B:-0.647535201212;IKZF1:-0.652276764883;ATF2:-0.670412668351;STAT2,4,6:-0.670912375871;AR:-0.682714016882;SOX2:-0.683724213773;RREB1:-0.684890422772;NKX2-1,4:-0.692926759861;ZFP161:-0.699125773591;SMAD1..7,9:-0.700639341935;CEBPA,B_DDIT3:-0.705325844886;GCM1,2:-0.756185174716;SREBF1,2:-0.760402067168;MZF1:-0.776635393088;FOXM1:-0.804040561173;NKX3-1:-0.824731007313;ZIC1..3:-0.835601117687;EGR1..3:-0.849907834962;PAX1,9:-0.859908453032;HLF:-0.874797674652;ZNF148:-0.875465676249;ZNF423:-0.882937654491;MYBL2:-0.890678780234;NFIL3:-0.907074869257;XCPE1{core}:-0.913769635178;HOX{A6,A7,B6,B7}:-0.921675786038;TAL1_TCF{3,4,12}:-0.938339869095;MYFfamily:-0.945799503784;MTF1:-0.951649609659;NFE2L1:-0.953544095458;FOXD3:-0.973768246519;STAT5{A,B}:-0.978216046772;EN1,2:-0.978922181088;NFIX:-0.985588041258;NHLH1,2:-0.997141009026;MTE{core}:-1.05876297818;RFX1:-1.05930740569;FOXO1,3,4:-1.06593389542;GTF2I:-1.09007135543;REST:-1.09575237094;HIC1:-1.12014607275;TBX4,5:-1.1511847893;TFCP2:-1.16692019084;TBP:-1.18468252249;JUN:-1.19084836748;TFAP2{A,C}:-1.20416131274;T:-1.26437579519;NFE2L2:-1.27296059266;MAFB:-1.28862710194;MED-1{core}:-1.29285050559;PAX5:-1.29937083569;PATZ1:-1.32027730193;GTF2A1,2:-1.398656519;ATF6:-1.44177580126;NANOG:-1.44513552895;HMX1:-1.45211728268;ZNF238:-1.47843747883;MAZ:-1.49919773716;XBP1:-1.508255553;ZBTB6:-1.53106261566;POU6F1:-1.54602585759;SP1:-1.56632362375;TLX1..3_NFIC{dimer}:-1.59610391045;GZF1:-1.6211028518;TEAD1:-1.62386607827;TFAP2B:-1.78351770508;NR3C1:-1.80161616989;FOX{D1,D2}:-1.8019984133;FOX{I1,J2}:-2.26010040779;FOXL1:-2.73939779279
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10821-111C2;search_select_hide=table117:FF:10821-111C2
}}
}}

Latest revision as of 15:07, 3 June 2020

Name:B lymphoblastoid cell line: GM12878 ENCODE, biol_rep1
Species:Human (Homo sapiens)
Library ID:CNhs12331
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stageNA
sexfemale
ageNA
cell typeb cell
cell lineGM12878
companyNA
collaborationCarrie Davis (Cold spring Harbor Laboratories)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005328
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs12331 CAGE DRX007776 DRR008648
Accession ID Hg19

Library idBAMCTSS
CNhs12331 DRZ000073 DRZ001458
Accession ID Hg38

Library idBAMCTSS
CNhs12331 DRZ011423 DRZ012808
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.0845
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0.032
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.644
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
C114-teratocarcinoma-medulloblastoma-carcinosarcoma-iPS-anaplastic-acute-neuroblastoma0
C115-pituitary-Neural-caudate-putamen-amygdala-medulla-hippocampus0
C116-myeloma-xeroderma-tonsil-CD19-spleen-lymph-trachea0
C117-serous-clear-kidney-neuroectodermal-mesothelioma-endometrial-Intestinal0
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C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12331

Jaspar motifP-value
MA0002.20.00316
MA0003.10.868
MA0004.10.0765
MA0006.10.251
MA0007.10.391
MA0009.10.948
MA0014.10.475
MA0017.10.0117
MA0018.20.544
MA0019.10.341
MA0024.14.69627e-7
MA0025.10.116
MA0027.10.757
MA0028.12.38387e-5
MA0029.10.747
MA0030.10.0114
MA0031.10.0367
MA0035.20.928
MA0038.10.878
MA0039.20.586
MA0040.10.0654
MA0041.10.16
MA0042.10.247
MA0043.10.126
MA0046.10.00371
MA0047.20.436
MA0048.10.576
MA0050.13.62122e-19
MA0051.16.97248e-14
MA0052.10.511
MA0055.10.0336
MA0057.10.751
MA0058.10.0584
MA0059.10.00247
MA0060.10.00216
MA0061.16.21928e-14
MA0062.21.2435e-10
MA0065.20.0164
MA0066.10.444
MA0067.10.947
MA0068.10.093
MA0069.10.235
MA0070.10.352
MA0071.10.43
MA0072.10.799
MA0073.10.527
MA0074.10.89
MA0076.19.06769e-8
MA0077.10.204
MA0078.10.0976
MA0079.20.246
MA0080.21.9526e-7
MA0081.10.00808
MA0083.10.786
MA0084.10.546
MA0087.10.496
MA0088.10.0102
MA0090.15.64177e-6
MA0091.10.422
MA0092.10.583
MA0093.10.0688
MA0099.20.00546
MA0100.10.133
MA0101.12.65106e-17
MA0102.20.222
MA0103.10.0258
MA0104.20.00114
MA0105.16.74348e-12
MA0106.10.0814
MA0107.14.94278e-18
MA0108.21.09928e-7
MA0111.10.308
MA0112.20.154
MA0113.10.808
MA0114.10.00952
MA0115.10.367
MA0116.13.43673e-5
MA0117.10.715
MA0119.10.784
MA0122.10.427
MA0124.10.989
MA0125.10.175
MA0131.10.114
MA0135.10.689
MA0136.19.303e-10
MA0137.20.336
MA0138.20.409
MA0139.10.138
MA0140.10.597
MA0141.10.0821
MA0142.10.356
MA0143.10.618
MA0144.10.275
MA0145.10.639
MA0146.10.295
MA0147.13.73699e-4
MA0148.10.253
MA0149.10.455
MA0150.10.845
MA0152.10.311
MA0153.10.483
MA0154.11.72663e-5
MA0155.10.737
MA0156.15.24559e-11
MA0157.10.0376
MA0159.10.246
MA0160.10.0416
MA0162.10.664
MA0163.12.82246e-11
MA0164.10.628
MA0258.10.0349
MA0259.10.0308



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12331

Novel motifP-value
10.00864
100.0283
1000.45
1010.197
1020.461
1030.175
1040.717
1050.655
1060.91
1070.715
1080.897
1090.0522
110.18
1100.148
1110.0743
1120.0766
1130.607
1140.423
1150.36
1160.452
1170.0202
1180.0942
1190.171
120.9
1200.47
1210.839
1220.546
1233.95907e-5
1240.0686
1250.326
1260.227
1270.257
1280.677
1290.544
130.0935
1300.687
1310.304
1320.809
1330.763
1340.679
1350.892
1360.122
1370.851
1380.813
1390.527
140.764
1400.292
1410.0688
1420.899
1430.396
1440.704
1450.0567
1460.64
1470.235
1480.0906
1490.507
150.0608
1500.868
1510.696
1520.127
1530.703
1540.897
1550.17
1560.848
1570.135
1580.845
1590.135
160.982
1600.203
1610.0302
1620.991
1630.77
1640.0839
1650.702
1660.243
1670.4
1680.426
1690.588
170.816
180.618
190.67
20.715
200.241
210.147
220.915
230.346
240.198
250.113
260.0598
270.533
280.364
290.0229
30.0447
300.118
310.879
320.582
330.337
340.627
350.153
360.0363
370.284
380.318
390.459
40.808
400.426
410.734
420.0796
430.417
440.149
450.413
460.249
470.0292
480.0553
490.314
50.683
500.802
510.641
520.281
530.362
540.819
550.445
560.746
570.226
580.071
590.22
60.901
600.975
610.109
620.0793
630.65
640.214
650.892
660.536
670.866
680.0876
690.682
70.12
700.466
710.019
720.375
730.899
740.652
750.00699
760.505
770.772
780.0238
790.922
80.61
800.166
810.437
820.681
830.579
840.209
850.482
860.32
870.0878
880.697
890.836
90.861
900.326
910.738
920.517
930.214
940.782
950.0125
960.729
970.142
980.498
990.269



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs12331


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000945 (lymphocyte of B lineage)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0101035 (hematopoietic cell line sample)
0100773 (lymphoblastoid cell line sample)
0101522 (B-lymphocyte cell line sample)
0102062 (B-lymphoblastoid cell line sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)

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