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{{f5samples
{{f5samples
|id=FF:10840-111E3
|DRA_sample_Accession=CAGE@SAMD00004916
|name=plasma cell leukemia cell line:ARH-77
|accession_numbers=CAGE;DRX007985;DRR008857;DRZ000282;DRZ001667;DRZ011632;DRZ013017
|sample_id=10840
|ancestors_in_anatomy_facet=
|rna_tube_id=111E3
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000151,CL:0002371,CL:0000542,CL:0000219,CL:0000945,CL:0000738,CL:0002087,CL:0002242,CL:0000255,CL:0000946,CL:0000786
|rna_box=111
|rna_position=E3
|sample_cell_lot=
|sample_cell_catalog=CRL1621
|sample_company=ATCC
|rna_lot_number=
|rna_catalog_number=
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_dev_stage=
|sample_tissue=blood
|sample_donor(cell lot)=
|sample_sex=female
|sample_age=33
|sample_ethnicity=C
|rna_rin=
|rna_od260/230=2.05
|rna_od260/280=2.07
|sample_cell_type=plasma cell
|sample_cell_line=ARH-77
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_experimental_condition=
|sample_disease=plasma cell leukemia
|rna_sample_type=total RNA
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_weight_ug=35.28576
|rna_concentration=1.30688
|sample_note=
|profile_hcage=CNhs12807,LSID972,release012,COMPLETED
|profile_cagescan=,,,
|profile_srnaseq=,,,
|profile_rnaseq=,,,
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000004,CL:0000012,CL:0000034,CL:0000037,CL:0000048,CL:0000051,CL:0000063,CL:0000134,CL:0000144,CL:0000219,CL:0000236,CL:0000255,CL:0000542,CL:0000548,CL:0000566,CL:0000723,CL:0000738,CL:0000785,CL:0000786,CL:0000816,CL:0000817,CL:0000818,CL:0000826,CL:0000837,CL:0000838,CL:0000945,CL:0000946,CL:0000954,CL:0000955,CL:0000980,CL:0000988,CL:0002031,CL:0002032,CL:0002087,CL:0002320,CL:0002371
|ancestors_in_anatomy_facet=UBERON:0000061,UBERON:0000465,UBERON:0000479,UBERON:0001062,UBERON:0002384
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|sample_description=
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0101035,FF:0100773,FF:0101522,FF:0102062,FF:0102992
|comment=
|created_by=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
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X2!0.82!26.85!TOX2;;chr1:151319654..151319698,-!p2@RFX5!0.82!12.79!RFX5;;chr1:23857698..23857733,-!p1@E2F2!0.82!10.83!E2F2;;chr5:133450365..133450444,+!p1@TCF7!0.81!26.85!TCF7;;chr17:42295777..42295816,-!p7@UBTF!0.81!6.80!UBTF;;chr17:46620898..46620927,-!p9@HOXB2!0.81!6.57!HOXB2;;chr6:34204973..34204990,+!p4@HMGA1!0.80!76.63!HMGA1;;chr10:35415951..35415975,+!p8@CREM!0.80!7.61!CREM;;chr18:6414884..6414942,-!p1@L3MBTL4!0.80!6.80!L3MBTL4;;chr7:28610060..28610073,+!p9@CREB5!0.80!5.30!CREB5;;chr2:100759010..100759035,-!p1@AFF3!0.80!5.30!AFF3;;chr2:63277948..63277974,+!p1@OTX1!0.80!5.30!OTX1;;chr10:104155480..104155534,+!p2@NFKB2!0.79!36.30!NFKB2;;chr9:37034469..37034474,-!p1@PAX5!0.79!5.19!PAX5;;chr19:42627037..42627084,-!p3@POU2F2!0.78!5.07!POU2F2;;chr3:141103634..141103665,+!p18@ZBTB38!0.78!5.07!ZBTB38;;chr17:38020557..38020572,-!p4@IKZF3!0.77!4.96!IKZF3;;chr17:37934204..37934241,-!p3@IKZF3!0.77!4.84!IKZF3;;chr18:52988979..52988993,-!p18@TCF4!0.77!4.84!TCF4;;chr9:77112225..77112238,+!p2@RORB!0.77!4.84!RORB;;chr6:41700616..41700664,-!p8@TFEB!0.77!4.84!TFEB;;chr8:135613895..135613921,-!p8@ZFAT!0.77!4.84!ZFAT;;chr2:214014959..214015006,-!p4@IKZF2!0.76!4.72!IKZF2;;chr12:103352277..103352324,+!p2@ASCL1!0.76!4.72!ASCL1;;chr2:97202480..97202499,+!p1@ARID5A!0.75!51.97!ARID5A;;chr8:22550982..22550999,-!p1@EGR3!0.75!14.29!EGR3;;chrX:84499081..84499115,+!p2@ZNF711!0.75!7.14!ZNF711;;chr1:27023752..27023799,+!p4@ARID1A!0.75!6.34!ARID1A;;chr6:166581324..166581327,-!p7@T!0.75!4.61!T;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.74!22.36!TAL1;;chr2:214016496..214016544,-!p5@IKZF2!0.74!6.45!IKZF2;;chr8:135577784..135577795,-!p15@ZFAT!0.74!4.49!ZFAT;;chr17:36105042..36105060,-!p1@HNF1B!0.74!4.49!HNF1B;;chr11:19262421..19262455,-!p3@E2F8!0.74!4.49!E2F8;;chr10:35484053..35484076,+!p1@CREM!0.73!11.75!CREM;;chr5:158526756..158526797,-!p3@EBF1!0.73!4.38!EBF1;;chr7:50344289..50344323,+!p1@IKZF1!0.73!4.38!IKZF1;;chr2:214016254..214016282,-!p7@IKZF2!0.73!4.38!IKZF2;;chr6:144385698..144385742,-!p2@PLAGL1!0.72!5.30!PLAGL1;;chr4:146859626..146859669,-!p2@ZNF827!0.71!6.22!ZNF827;;chr15:76629097..76629120,+!p2@ISL2!0.71!4.72!ISL2;;chr17:37934188..37934202,-!p8@IKZF3!0.71!4.15!IKZF3;;chr9:37027156..37027193,-!p4@PAX5!0.71!4.15!PAX5;;chr8:135613849..135613883,-!p7@ZFAT!0.70!4.03!ZFAT;;chr8:72755987..72756002,-!p7@MSC!0.70!4.03!MSC;;chr13:79177703..79177729,-!p2@POU4F1!0.70!4.03!POU4F1;;chr1:212782094..212782109,+!p1@ATF3!0.69!123.19!ATF3;;chr9:2015306..2015323,+!p3@SMARCA2!0.69!11.18!SMARCA2;;chr5:172662230..172662241,-!p3@NKX2-5!0.69!3.92!NKX2-5;;chr7:115799916..115799932,-!p6@TFEC!0.69!3.92!TFEC;;chr6:44233252..44233296,-!p1@NFKBIE!0.68!42.64!NFKBIE;;chr12:11802753..11802834,+!p2@ETV6!0.68!21.09!ETV6;;chr18:77155922..77155939,+!p1@NFATC1!0.68!11.52!NFATC1;;chr8:128747661..128747703,+!p6@MYC!0.68!5.30!MYC;;chr7:28452130..28452154,+!p10@CREB5!0.68!3.80!CREB5;;chr19:50432453..50432468,+!p1@ATF5!0.67!242.11!ATF5;;chr8:72756267..72756296,-!p4@MSC!0.67!5.76!MSC;;chr7:50344251..50344288,+!p3@IKZF1!0.67!3.69!IKZF1;;chr9:2015335..2015370,+!p1@SMARCA2!0.66!50.82!SMARCA2;;chr15:74833584..74833626,+!p1@ARID3B!0.66!9.22!ARID3B;;chr19:19729477..19729542,-!p1@PBX4!0.66!8.41!PBX4;;chr12:54785074..54785122,-!p2@ZNF385A!0.66!5.88!ZNF385A;;chr7:28448995..28449011,+!p4@CREB5!0.66!5.30!CREB5;;chr3:18486354..18486377,-!p2@SATB1!0.66!4.61!SATB1;;chr6:135502501..135502546,+!p1@MYB!0.66!4.38!MYB;;chr11:19262461..19262476,-!p5@E2F8!0.66!3.57!E2F8;;chr2:214017168..214017189,-!p8@IKZF2!0.66!3.57!IKZF2;;chr19:45971246..45971265,+!p1@FOSB!0.65!75.02!FOSB;;chr10:111967345..111967422,+!p1@MXI1!0.65!65.68!MXI1;;chr7:64838786..64838809,+!p2@ZNF92!0.65!23.05!ZNF92;;chr11:128392309..128392350,-!p3@ETS1!0.65!9.10!ETS1;;chr9:127533519..127533573,-!p2@NR6A1!0.65!4.38!NR6A1;;chr16:85936539..85936562,+!p3@IRF8!0.65!3.46!IRF8;;chr8:128748308..128748324,+!p2@MYC!0.64!110.97!MYC;;chr10:104154246..104154347,+!p3@NFKB2!0.64!24.20!NFKB2;;chr2:148778973..148779035,+!p3@MBD5!0.64!9.79!MBD5;;chrX:84498989..84499003,+!p1@ZNF711!0.64!4.84!ZNF711;;chr7:14028743..14028799,-!p3@ETV1!0.64!4.49!ETV1;;chr20:56195474..56195506,-!p1@ZBP1!0.64!3.34!ZBP1;;chr2:191878874..191878938,-!p1@STAT1!0.63!209.61!STAT1;;chr8:60031619..60031676,-!p1@TOX!0.63!7.84!TOX;;chr5:88179518..88179569,-!p5@MEF2C!0.63!4.61!MEF2C;;chr20:44600199..44600219,-!p3@ZNF335!0.63!4.61!ZNF335;;chr1:25291648..25291665,-!p7@RUNX3!0.63!3.23!RUNX3;;chr2:68615063..68615089,+!p4@PLEK!0.63!3.23!PLEK;;chr4:106068026..106068084,+!p1@TET2!0.62!33.76!TET2;;chr13:74708029..74708077,-!p2@KLF12!0.62!10.49!KLF12;;chr12:54447599..54447630,+!p3@HOXC4!0.62!4.03!HOXC4;;chr8:81397876..81397898,+!p5@ZBTB10!0.62!3.92!ZBTB10;;chr7:21467674..21467727,+!p1@SP4!0.61!14.17!SP4;;chr5:158526917..158526932,-!p1@EBF1!0.61!8.64!EBF1;;chr11:6947720..6947812,+!p1@ZNF215!0.61!4.26!ZNF215;;chr5:322733..322758,+!p2@AHRR!0.61!3.11!AHRR;;chr14:74226961..74227020,-!p1@C14orf43!0.60!23.28!C14orf43;;chr2:192015701..192015743,-!p1@STAT4!0.60!4.38!STAT4;;chr8:72756023..7275605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|rna_box=111
|rna_catalog_number=
|rna_concentration=1.30688
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_lot_number=
|rna_od260/230=2.05
|rna_od260/280=2.07
|rna_position=E3
|rna_rin=
|rna_sample_type=total RNA
|rna_tube_id=1.11E+05
|rna_weight_ug=35.28576
|sample_age=33
|sample_category=cell lines
|sample_cell_catalog=CRL1621
|sample_cell_line=ARH-77
|sample_cell_lot=
|sample_cell_type=plasma cell
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest)
|sample_company=ATCC
|sample_description=
|sample_dev_stage=
|sample_disease=plasma cell leukemia
|sample_donor(cell lot)=
|sample_ethnicity=C
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.67741938041552e-273!GO:0043227;membrane-bound organelle;3.29626793885442e-238!GO:0043231;intracellular membrane-bound organelle;8.51103477657043e-238!GO:0043226;organelle;2.8373379969928e-231!GO:0043229;intracellular organelle;2.05359877937386e-230!GO:0005737;cytoplasm;9.07779510282868e-177!GO:0044422;organelle part;1.311441078211e-159!GO:0044446;intracellular organelle part;2.27053759349604e-157!GO:0032991;macromolecular complex;2.04912395230785e-122!GO:0005634;nucleus;1.20535046082547e-120!GO:0044444;cytoplasmic part;1.97719643701729e-119!GO:0044237;cellular metabolic process;7.70449663136647e-112!GO:0044238;primary metabolic process;7.91530134357662e-110!GO:0043170;macromolecule metabolic process;4.42864502594786e-106!GO:0030529;ribonucleoprotein complex;4.01016473163704e-98!GO:0044428;nuclear part;6.46201443130213e-97!GO:0003723;RNA binding;1.21189223289066e-91!GO:0043233;organelle lumen;5.00636260065897e-89!GO:0031974;membrane-enclosed lumen;5.00636260065897e-89!GO:0005515;protein binding;7.66481750949383e-79!GO:0005739;mitochondrion;2.79964073358792e-74!GO:0043283;biopolymer metabolic process;5.05565364607917e-72!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.06129678030828e-65!GO:0043234;protein complex;1.78910210989182e-63!GO:0006412;translation;1.21635704602378e-61!GO:0006396;RNA processing;9.7456064225287e-61!GO:0010467;gene expression;1.70412440250063e-60!GO:0031981;nuclear lumen;1.04188633220367e-57!GO:0005840;ribosome;2.15908207916685e-55!GO:0044429;mitochondrial part;4.50278685880831e-51!GO:0019538;protein metabolic process;4.90664969744792e-50!GO:0006259;DNA metabolic process;1.03417048732901e-49!GO:0016071;mRNA metabolic process;2.47719101241041e-49!GO:0003735;structural constituent of ribosome;2.17788506160991e-48!GO:0031967;organelle envelope;1.39193708518923e-47!GO:0031090;organelle membrane;2.28045385497139e-47!GO:0031975;envelope;3.82227128242229e-47!GO:0033036;macromolecule localization;1.43751718098277e-45!GO:0044267;cellular protein metabolic process;3.041437721295e-45!GO:0044260;cellular macromolecule metabolic process;5.61880253561607e-45!GO:0003676;nucleic acid binding;9.86570139479189e-45!GO:0008380;RNA splicing;1.48544794618586e-44!GO:0009058;biosynthetic process;2.18403115804899e-44!GO:0009059;macromolecule biosynthetic process;5.25587496223642e-44!GO:0044249;cellular biosynthetic process;6.38322332099246e-44!GO:0015031;protein transport;7.16126077858606e-44!GO:0016043;cellular component organization and biogenesis;9.19277610010049e-43!GO:0006397;mRNA processing;1.53910181370531e-42!GO:0033279;ribosomal subunit;4.47946252868252e-42!GO:0045184;establishment of protein localization;9.26725268070694e-42!GO:0008104;protein localization;3.4690143665683e-41!GO:0006996;organelle organization and biogenesis;4.82741202065171e-40!GO:0005829;cytosol;4.67346613304666e-39!GO:0007049;cell cycle;4.01628571669166e-38!GO:0046907;intracellular transport;1.14373832331264e-37!GO:0005654;nucleoplasm;7.6448437072649e-37!GO:0065003;macromolecular complex assembly;1.75661437834957e-36!GO:0043228;non-membrane-bound organelle;2.26429675511878e-36!GO:0043232;intracellular non-membrane-bound organelle;2.26429675511878e-36!GO:0022613;ribonucleoprotein complex biogenesis and assembly;6.01261523742393e-36!GO:0000166;nucleotide binding;6.41939137554649e-34!GO:0005681;spliceosome;2.04827809784091e-32!GO:0022607;cellular component assembly;1.09851873929314e-31!GO:0005740;mitochondrial envelope;1.90345684767566e-31!GO:0006886;intracellular protein transport;2.34990296823488e-31!GO:0022402;cell cycle process;7.72938935474482e-31!GO:0016070;RNA metabolic process;1.22420693996463e-30!GO:0031966;mitochondrial membrane;3.86588862483391e-29!GO:0006974;response to DNA damage stimulus;4.28125505637873e-29!GO:0051649;establishment of cellular localization;4.45182317995327e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.66008790536722e-29!GO:0019866;organelle inner membrane;5.50066938036355e-29!GO:0005694;chromosome;1.21048402498865e-28!GO:0000278;mitotic cell cycle;1.80386482162021e-28!GO:0051641;cellular localization;2.32245324400634e-28!GO:0044451;nucleoplasm part;2.340229751075e-28!GO:0044445;cytosolic part;3.32338957144343e-27!GO:0005743;mitochondrial inner membrane;2.54439517121359e-26!GO:0044427;chromosomal part;4.73750808984418e-26!GO:0012501;programmed cell death;5.01055281071233e-26!GO:0006915;apoptosis;5.11728579907148e-26!GO:0006281;DNA repair;8.06944021129126e-25!GO:0022403;cell cycle phase;3.55679847979197e-24!GO:0032553;ribonucleotide binding;4.87194745336409e-24!GO:0032555;purine ribonucleotide binding;4.87194745336409e-24!GO:0016462;pyrophosphatase activity;1.47197134739119e-23!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.51289852004445e-23!GO:0016817;hydrolase activity, acting on acid anhydrides;2.01329821366716e-23!GO:0000087;M phase of mitotic cell cycle;2.10063125198999e-23!GO:0031980;mitochondrial lumen;2.23274723389832e-23!GO:0005759;mitochondrial matrix;2.23274723389832e-23!GO:0017076;purine nucleotide binding;3.87615408927716e-23!GO:0044455;mitochondrial membrane part;4.19926880449509e-23!GO:0007067;mitosis;4.86077655663816e-23!GO:0017111;nucleoside-triphosphatase activity;6.59871595575813e-23!GO:0008219;cell death;6.7704942293541e-23!GO:0016265;death;6.7704942293541e-23!GO:0051276;chromosome organization and biogenesis;1.53064858769311e-22!GO:0005730;nucleolus;2.63755628967981e-22!GO:0044265;cellular macromolecule catabolic process;3.68541941011796e-22!GO:0006119;oxidative phosphorylation;4.97415232339317e-22!GO:0015934;large ribosomal subunit;8.63955653195856e-22!GO:0006512;ubiquitin cycle;1.64697535764048e-21!GO:0015935;small ribosomal subunit;1.99165044368897e-21!GO:0008134;transcription factor binding;2.98836271715584e-21!GO:0016874;ligase activity;1.15622504412983e-20!GO:0000279;M phase;3.49039276416672e-20!GO:0022618;protein-RNA complex assembly;6.84168824233504e-20!GO:0005524;ATP binding;9.12276488060574e-20!GO:0006260;DNA replication;1.31806916125102e-19!GO:0051301;cell division;1.46957798114715e-19!GO:0043285;biopolymer catabolic process;1.76970351732383e-19!GO:0032559;adenyl ribonucleotide binding;3.51538336593803e-19!GO:0006457;protein folding;4.63019449132369e-19!GO:0012505;endomembrane system;5.28069141221889e-19!GO:0009057;macromolecule catabolic process;1.34039135947871e-18!GO:0019941;modification-dependent protein catabolic process;2.21430097403241e-18!GO:0043632;modification-dependent macromolecule catabolic process;2.21430097403241e-18!GO:0009719;response to endogenous stimulus;2.48030210494623e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;2.89921265860729e-18!GO:0044248;cellular catabolic process;3.63639469277409e-18!GO:0030554;adenyl nucleotide binding;3.68606816193653e-18!GO:0005746;mitochondrial respiratory chain;4.10618783815982e-18!GO:0044257;cellular protein catabolic process;4.41078616148199e-18!GO:0006511;ubiquitin-dependent protein catabolic process;5.42227516045153e-18!GO:0000502;proteasome complex (sensu Eukaryota);1.94278121695587e-17!GO:0006605;protein targeting;4.40020188829376e-17!GO:0005635;nuclear envelope;4.40020188829376e-17!GO:0051726;regulation of cell cycle;4.65401324094254e-17!GO:0005761;mitochondrial ribosome;5.81985254790853e-17!GO:0000313;organellar ribosome;5.81985254790853e-17!GO:0043412;biopolymer modification;6.90190801290026e-17!GO:0000074;regulation of progression through cell cycle;7.02175131824022e-17!GO:0042254;ribosome biogenesis and assembly;8.7161900236109e-17!GO:0008135;translation factor activity, nucleic acid binding;1.39295008408572e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.54026077271853e-16!GO:0050136;NADH dehydrogenase (quinone) activity;2.6312862447029e-16!GO:0003954;NADH dehydrogenase activity;2.6312862447029e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.6312862447029e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.05385697228043e-16!GO:0031965;nuclear membrane;6.36791947914991e-16!GO:0000398;nuclear mRNA splicing, via spliceosome;6.7713788126173e-16!GO:0000375;RNA splicing, via transesterification reactions;6.7713788126173e-16!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;6.7713788126173e-16!GO:0006323;DNA packaging;6.83167171673907e-16!GO:0006913;nucleocytoplasmic transport;1.0480655846728e-15!GO:0016604;nuclear body;2.49923263626246e-15!GO:0042981;regulation of apoptosis;2.71022160858573e-15!GO:0051169;nuclear transport;2.90106529510468e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.64406835943139e-15!GO:0043067;regulation of programmed cell death;4.42313316733633e-15!GO:0006464;protein modification process;1.18585766708041e-14!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.2020881848928e-14!GO:0030163;protein catabolic process;1.98988423537093e-14!GO:0003712;transcription cofactor activity;2.05380195823216e-14!GO:0044453;nuclear membrane part;2.38611714017492e-14!GO:0051082;unfolded protein binding;3.1885955201846e-14!GO:0048770;pigment granule;3.25482110201366e-14!GO:0042470;melanosome;3.25482110201366e-14!GO:0042775;organelle ATP synthesis coupled electron transport;3.25482110201366e-14!GO:0042773;ATP synthesis coupled electron transport;3.25482110201366e-14!GO:0030964;NADH dehydrogenase complex (quinone);3.66598312713143e-14!GO:0045271;respiratory chain complex I;3.66598312713143e-14!GO:0005747;mitochondrial respiratory chain complex I;3.66598312713143e-14!GO:0005783;endoplasmic reticulum;4.61584496568042e-14!GO:0050794;regulation of cellular process;7.5793889420014e-14!GO:0043687;post-translational protein modification;8.00802294443564e-14!GO:0042623;ATPase activity, coupled;8.07771076326283e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.08338326336221e-13!GO:0016887;ATPase activity;1.74108272357512e-13!GO:0000785;chromatin;1.86502942763565e-13!GO:0006366;transcription from RNA polymerase II promoter;2.04009909018637e-13!GO:0004386;helicase activity;2.30111375236631e-13!GO:0006333;chromatin assembly or disassembly;3.34896490099364e-13!GO:0065004;protein-DNA complex assembly;7.6668615718874e-13!GO:0044432;endoplasmic reticulum part;1.09686685401208e-12!GO:0005643;nuclear pore;1.60323666198322e-12!GO:0051186;cofactor metabolic process;2.57057217295169e-12!GO:0006446;regulation of translational initiation;3.26064490234345e-12!GO:0006413;translational initiation;4.57834316818677e-12!GO:0050657;nucleic acid transport;6.46753186635117e-12!GO:0051236;establishment of RNA localization;6.46753186635117e-12!GO:0050658;RNA transport;6.46753186635117e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;6.46753186635117e-12!GO:0006403;RNA localization;6.56309726327426e-12!GO:0048193;Golgi vesicle transport;7.07351895705369e-12!GO:0017038;protein import;7.66140383313391e-12!GO:0016607;nuclear speck;1.05895391419369e-11!GO:0006364;rRNA processing;2.70781166654632e-11!GO:0065002;intracellular protein transport across a membrane;3.83751967652425e-11!GO:0003743;translation initiation factor activity;3.87345522812065e-11!GO:0016072;rRNA metabolic process;5.31359175208118e-11!GO:0008639;small protein conjugating enzyme activity;7.66829333010926e-11!GO:0016779;nucleotidyltransferase activity;8.35422651335023e-11!GO:0006399;tRNA metabolic process;1.37918960651505e-10!GO:0004842;ubiquitin-protein ligase activity;1.53196129590657e-10!GO:0008026;ATP-dependent helicase activity;1.56740901610247e-10!GO:0005794;Golgi apparatus;2.25061219296544e-10!GO:0009056;catabolic process;2.2765754608583e-10!GO:0042175;nuclear envelope-endoplasmic reticulum network;2.31169980114065e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.57989786868067e-10!GO:0006261;DNA-dependent DNA replication;2.5915783881835e-10!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.70428420907831e-10!GO:0019787;small conjugating protein ligase activity;3.33712198339531e-10!GO:0005789;endoplasmic reticulum membrane;3.33712198339531e-10!GO:0016568;chromatin modification;3.64714418419467e-10!GO:0051246;regulation of protein metabolic process;3.6766278084482e-10!GO:0046930;pore complex;5.2257579320067e-10!GO:0006732;coenzyme metabolic process;6.28211372917658e-10!GO:0051028;mRNA transport;6.54920234186317e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;7.4050649829775e-10!GO:0000775;chromosome, pericentric region;8.20508293094879e-10!GO:0006793;phosphorus metabolic process;8.47967245261639e-10!GO:0006796;phosphate metabolic process;8.47967245261639e-10!GO:0009055;electron carrier activity;9.29709765827981e-10!GO:0006334;nucleosome assembly;1.15604409320153e-09!GO:0043566;structure-specific DNA binding;1.16371926658401e-09!GO:0019222;regulation of metabolic process;1.21139834285739e-09!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.26728843878399e-09!GO:0050789;regulation of biological process;1.36554031878877e-09!GO:0009259;ribonucleotide metabolic process;1.4955281381621e-09!GO:0007005;mitochondrion organization and biogenesis;1.77842913128143e-09!GO:0006461;protein complex assembly;1.95907246939688e-09!GO:0031497;chromatin assembly;2.39225187562627e-09!GO:0016563;transcription activator activity;2.65168156357564e-09!GO:0048523;negative regulation of cellular process;2.77178482705346e-09!GO:0006163;purine nucleotide metabolic process;3.57387447990963e-09!GO:0003697;single-stranded DNA binding;3.92965728377511e-09!GO:0016881;acid-amino acid ligase activity;4.3082214972372e-09!GO:0009615;response to virus;5.02227055618638e-09!GO:0006164;purine nucleotide biosynthetic process;7.35874363802275e-09!GO:0030532;small nuclear ribonucleoprotein complex;8.05037924215594e-09!GO:0006916;anti-apoptosis;8.05493823457559e-09!GO:0043069;negative regulation of programmed cell death;9.20968760747708e-09!GO:0009260;ribonucleotide biosynthetic process;9.69080814136856e-09!GO:0016192;vesicle-mediated transport;1.01022785886759e-08!GO:0008565;protein transporter activity;1.03333437460925e-08!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.03343902615847e-08!GO:0003713;transcription coactivator activity;1.06472173332014e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.09669974524476e-08!GO:0043066;negative regulation of apoptosis;1.18798547504957e-08!GO:0051170;nuclear import;2.11066177066343e-08!GO:0009060;aerobic respiration;2.20869627024183e-08!GO:0000075;cell cycle checkpoint;2.22847783047219e-08!GO:0016310;phosphorylation;2.31083349097768e-08!GO:0009150;purine ribonucleotide metabolic process;2.47352584418491e-08!GO:0045333;cellular respiration;2.54058800925997e-08!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;2.97045575863772e-08!GO:0004812;aminoacyl-tRNA ligase activity;2.97045575863772e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;2.97045575863772e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.97553853405113e-08!GO:0051325;interphase;4.04772454779727e-08!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.26332496960813e-08!GO:0005819;spindle;4.47756206058448e-08!GO:0005839;proteasome core complex (sensu Eukaryota);4.75201968730832e-08!GO:0016740;transferase activity;4.79897188440933e-08!GO:0051188;cofactor biosynthetic process;4.81927676555905e-08!GO:0009152;purine ribonucleotide biosynthetic process;5.03015668321701e-08!GO:0006606;protein import into nucleus;5.5524559208067e-08!GO:0043038;amino acid activation;5.57364821937817e-08!GO:0006418;tRNA aminoacylation for protein translation;5.57364821937817e-08!GO:0043039;tRNA aminoacylation;5.57364821937817e-08!GO:0051329;interphase of mitotic cell cycle;6.95052531143024e-08!GO:0019899;enzyme binding;7.2364786578425e-08!GO:0016787;hydrolase activity;8.86295890502305e-08!GO:0048519;negative regulation of biological process;9.20672183601973e-08!GO:0000245;spliceosome assembly;9.59226883283719e-08!GO:0032446;protein modification by small protein conjugation;9.69923689766796e-08!GO:0003924;GTPase activity;1.20132686969535e-07!GO:0019829;cation-transporting ATPase activity;1.24566957224841e-07!GO:0006888;ER to Golgi vesicle-mediated transport;1.37966310073858e-07!GO:0030120;vesicle coat;1.50020063394811e-07!GO:0030662;coated vesicle membrane;1.50020063394811e-07!GO:0031323;regulation of cellular metabolic process;1.60650687934383e-07!GO:0005793;ER-Golgi intermediate compartment;1.66204364262316e-07!GO:0007243;protein kinase cascade;1.67426285197826e-07!GO:0043065;positive regulation of apoptosis;1.68625752729195e-07!GO:0007088;regulation of mitosis;1.85841645986658e-07!GO:0005657;replication fork;1.92115938626264e-07!GO:0015986;ATP synthesis coupled proton transport;2.01306216598519e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.01306216598519e-07!GO:0007051;spindle organization and biogenesis;2.13799909916757e-07!GO:0016567;protein ubiquitination;2.17196348166593e-07!GO:0005525;GTP binding;2.45497529805187e-07!GO:0043068;positive regulation of programmed cell death;2.50623540657455e-07!GO:0048475;coated membrane;2.81521583426198e-07!GO:0030117;membrane coat;2.81521583426198e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.23485795408454e-07!GO:0015630;microtubule cytoskeleton;3.35612838483464e-07!GO:0004298;threonine endopeptidase activity;3.35612838483464e-07!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;3.48760340051358e-07!GO:0006099;tricarboxylic acid cycle;4.61166845418531e-07!GO:0046356;acetyl-CoA catabolic process;4.61166845418531e-07!GO:0015078;hydrogen ion transmembrane transporter activity;4.66279029270827e-07!GO:0005667;transcription factor complex;5.14804141196892e-07!GO:0045259;proton-transporting ATP synthase complex;5.31008134458352e-07!GO:0008094;DNA-dependent ATPase activity;5.71211086949338e-07!GO:0048522;positive regulation of cellular process;6.81773749472842e-07!GO:0031324;negative regulation of cellular metabolic process;7.64566113733673e-07!GO:0005768;endosome;7.80873679161694e-07!GO:0009142;nucleoside triphosphate biosynthetic process;1.06990226728567e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.06990226728567e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.12641990950917e-06!GO:0016564;transcription repressor activity;1.28650109748565e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.32465540605242e-06!GO:0006084;acetyl-CoA metabolic process;1.35381605382752e-06!GO:0045786;negative regulation of progression through cell cycle;1.35570131115748e-06!GO:0006310;DNA recombination;1.38518577321445e-06!GO:0009108;coenzyme biosynthetic process;1.43891951480383e-06!GO:0009141;nucleoside triphosphate metabolic process;1.44555459118104e-06!GO:0051168;nuclear export;1.52562680338836e-06!GO:0006754;ATP biosynthetic process;1.67176481308441e-06!GO:0006753;nucleoside phosphate metabolic process;1.67176481308441e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.00955444033573e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.00955444033573e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.40988594760522e-06!GO:0009144;purine nucleoside triphosphate metabolic process;2.40988594760522e-06!GO:0046034;ATP metabolic process;3.00566016431992e-06!GO:0003714;transcription corepressor activity;3.24050114788498e-06!GO:0009109;coenzyme catabolic process;3.47600865986788e-06!GO:0006350;transcription;3.57280627076508e-06!GO:0007059;chromosome segregation;3.66220512705578e-06!GO:0005762;mitochondrial large ribosomal subunit;3.83401484270734e-06!GO:0000315;organellar large ribosomal subunit;3.83401484270734e-06!GO:0006917;induction of apoptosis;4.09950742819712e-06!GO:0005770;late endosome;4.10645386012765e-06!GO:0006401;RNA catabolic process;4.28394502692256e-06!GO:0003899;DNA-directed RNA polymerase activity;4.28394502692256e-06!GO:0032561;guanyl ribonucleotide binding;4.38440547919859e-06!GO:0019001;guanyl nucleotide binding;4.38440547919859e-06!GO:0006302;double-strand break repair;4.43787569529782e-06!GO:0006613;cotranslational protein targeting to membrane;4.43787569529782e-06!GO:0003724;RNA helicase activity;4.76179235124309e-06!GO:0005813;centrosome;5.05880328280188e-06!GO:0051052;regulation of DNA metabolic process;5.15107940132824e-06!GO:0006417;regulation of translation;5.32387591553978e-06!GO:0012502;induction of programmed cell death;5.63926921390955e-06!GO:0051187;cofactor catabolic process;5.82048290568227e-06!GO:0065009;regulation of a molecular function;6.01077819789371e-06!GO:0009117;nucleotide metabolic process;6.38701684125545e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.61119295339e-06!GO:0016469;proton-transporting two-sector ATPase complex;6.77310564002573e-06!GO:0000786;nucleosome;6.89666705663274e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;8.52113382916344e-06!GO:0006752;group transfer coenzyme metabolic process;9.02271677346303e-06!GO:0005815;microtubule organizing center;1.0153980290218e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;1.02422178797613e-05!GO:0043623;cellular protein complex assembly;1.02621263499883e-05!GO:0065007;biological regulation;1.04232850127667e-05!GO:0000151;ubiquitin ligase complex;1.18098905973528e-05!GO:0010468;regulation of gene expression;1.50764524805242e-05!GO:0000314;organellar small ribosomal subunit;1.52893698330537e-05!GO:0005763;mitochondrial small ribosomal subunit;1.52893698330537e-05!GO:0009892;negative regulation of metabolic process;1.99367645827784e-05!GO:0004527;exonuclease activity;2.01628873985472e-05!GO:0008632;apoptotic program;2.17257701386498e-05!GO:0000776;kinetochore;2.60386560790002e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.84965117146835e-05!GO:0031072;heat shock protein binding;2.8713008259846e-05!GO:0007093;mitotic cell cycle checkpoint;3.26827174214995e-05!GO:0003690;double-stranded DNA binding;3.28738817381056e-05!GO:0003684;damaged DNA binding;3.29180085580393e-05!GO:0051427;hormone receptor binding;3.58196280131065e-05!GO:0006839;mitochondrial transport;3.76083933152677e-05!GO:0005798;Golgi-associated vesicle;3.92475532164041e-05!GO:0006402;mRNA catabolic process;3.9938492418617e-05!GO:0043021;ribonucleoprotein binding;4.09163874896427e-05!GO:0043681;protein import into mitochondrion;4.83476778280344e-05!GO:0048518;positive regulation of biological process;5.06936525333326e-05!GO:0006612;protein targeting to membrane;5.54816966834061e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.71519569197006e-05!GO:0031326;regulation of cellular biosynthetic process;5.88868726863026e-05!GO:0006414;translational elongation;6.0264576951543e-05!GO:0004518;nuclease activity;7.27772127150988e-05!GO:0044440;endosomal part;7.34321054847213e-05!GO:0010008;endosome membrane;7.34321054847213e-05!GO:0035257;nuclear hormone receptor binding;7.46468576576895e-05!GO:0051252;regulation of RNA metabolic process;7.64409714440142e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.75187611696465e-05!GO:0016363;nuclear matrix;8.6188879482373e-05!GO:0003729;mRNA binding;9.48535698655348e-05!GO:0003678;DNA helicase activity;0.000103755661833515!GO:0044431;Golgi apparatus part;0.000105636106840224!GO:0016481;negative regulation of transcription;0.000110049899485262!GO:0008654;phospholipid biosynthetic process;0.000110289107036437!GO:0007242;intracellular signaling cascade;0.000110869689161015!GO:0007006;mitochondrial membrane organization and biogenesis;0.000112051126586345!GO:0030880;RNA polymerase complex;0.000113724573270949!GO:0003677;DNA binding;0.000129262814315117!GO:0005773;vacuole;0.000139472974060691!GO:0030658;transport vesicle membrane;0.000140453883524343!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00015414794405029!GO:0000323;lytic vacuole;0.00017241437891841!GO:0005764;lysosome;0.00017241437891841!GO:0008186;RNA-dependent ATPase activity;0.000174227743553863!GO:0048468;cell development;0.000194621560607521!GO:0005048;signal sequence binding;0.00021558663319836!GO:0032774;RNA biosynthetic process;0.000224656749789206!GO:0006383;transcription from RNA polymerase III promoter;0.000225986277437545!GO:0006352;transcription initiation;0.000235914651155673!GO:0044452;nucleolar part;0.000235914651155673!GO:0000082;G1/S transition of mitotic cell cycle;0.000241414740040514!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000263100781959973!GO:0000428;DNA-directed RNA polymerase complex;0.000263100781959973!GO:0006351;transcription, DNA-dependent;0.000280542319678618!GO:0016741;transferase activity, transferring one-carbon groups;0.000322910091173852!GO:0009967;positive regulation of signal transduction;0.000323184038417249!GO:0048471;perinuclear region of cytoplasm;0.000352382421011913!GO:0042802;identical protein binding;0.000361902658772091!GO:0005885;Arp2/3 protein complex;0.00038396395827431!GO:0004674;protein serine/threonine kinase activity;0.00038396395827431!GO:0006950;response to stress;0.00038396395827431!GO:0051789;response to protein stimulus;0.000390781299754583!GO:0006986;response to unfolded protein;0.000390781299754583!GO:0016853;isomerase activity;0.000408729737478037!GO:0046822;regulation of nucleocytoplasmic transport;0.000413129776870675!GO:0016251;general RNA polymerase II transcription factor activity;0.000414183123547189!GO:0033673;negative regulation of kinase activity;0.000453584488264662!GO:0006469;negative regulation of protein kinase activity;0.000453584488264662!GO:0006626;protein targeting to mitochondrion;0.000469284355775613!GO:0009889;regulation of biosynthetic process;0.000475435780780087!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000491175728240698!GO:0008168;methyltransferase activity;0.00051218818883203!GO:0007052;mitotic spindle organization and biogenesis;0.000512736436093811!GO:0004004;ATP-dependent RNA helicase activity;0.000523193962816263!GO:0050790;regulation of catalytic activity;0.000559127108531439!GO:0051348;negative regulation of transferase activity;0.00056199569356205!GO:0030660;Golgi-associated vesicle membrane;0.000565622218621357!GO:0009165;nucleotide biosynthetic process;0.000568490933797947!GO:0015631;tubulin binding;0.000568490933797947!GO:0008033;tRNA processing;0.00057531167658995!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.0005904465167774!GO:0030867;rough endoplasmic reticulum membrane;0.000622922100582375!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000648213055246634!GO:0051223;regulation of protein transport;0.000729015794952189!GO:0016859;cis-trans isomerase activity;0.000738813516074758!GO:0031968;organelle outer membrane;0.00075237572672084!GO:0003746;translation elongation factor activity;0.000771609353261426!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000774019676176741!GO:0006611;protein export from nucleus;0.000785546473474583!GO:0032508;DNA duplex unwinding;0.00081872812951605!GO:0032392;DNA geometric change;0.00081872812951605!GO:0019867;outer membrane;0.000843568201013!GO:0045454;cell redox homeostasis;0.000930523742050453!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000945372827217379!GO:0048500;signal recognition particle;0.000945372827217379!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000960792733881858!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000960792733881858!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000960792733881858!GO:0031970;organelle envelope lumen;0.000962439551937792!GO:0005741;mitochondrial outer membrane;0.000965367285351882!GO:0006405;RNA export from nucleus;0.000990115003636505!GO:0043488;regulation of mRNA stability;0.00106964957696867!GO:0043487;regulation of RNA stability;0.00106964957696867!GO:0004532;exoribonuclease activity;0.00106964957696867!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00106964957696867!GO:0031982;vesicle;0.00108721292228197!GO:0030384;phosphoinositide metabolic process;0.00108981611711944!GO:0032200;telomere organization and biogenesis;0.00112830325998917!GO:0000723;telomere maintenance;0.00112830325998917!GO:0000049;tRNA binding;0.00112842204034627!GO:0031988;membrane-bound vesicle;0.00113492545780597!GO:0006650;glycerophospholipid metabolic process;0.00113492545780597!GO:0008312;7S RNA binding;0.00120244300260784!GO:0000139;Golgi membrane;0.00120539334158808!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00121742219778567!GO:0015399;primary active transmembrane transporter activity;0.00121742219778567!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00125997193182185!GO:0005769;early endosome;0.00130917036219262!GO:0043596;nuclear replication fork;0.00138005112957509!GO:0000228;nuclear chromosome;0.00139624666052865!GO:0006891;intra-Golgi vesicle-mediated transport;0.00140169861455387!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00142690851576629!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00142690851576629!GO:0003702;RNA polymerase II transcription factor activity;0.00143610461117577!GO:0046483;heterocycle metabolic process;0.00144351834659681!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00145169669086576!GO:0005637;nuclear inner membrane;0.00147842648888538!GO:0045449;regulation of transcription;0.00150657516114439!GO:0006270;DNA replication initiation;0.00152897439517736!GO:0007264;small GTPase mediated signal transduction;0.00153337217121784!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00155066487179634!GO:0007050;cell cycle arrest;0.00157034428376659!GO:0022411;cellular component disassembly;0.0015742899173196!GO:0005684;U2-dependent spliceosome;0.0015742899173196!GO:0051338;regulation of transferase activity;0.00159069796807364!GO:0003682;chromatin binding;0.00161258216800185!GO:0006268;DNA unwinding during replication;0.00169245211809443!GO:0047485;protein N-terminus binding;0.00180256555767231!GO:0005758;mitochondrial intermembrane space;0.00180335102445227!GO:0051920;peroxiredoxin activity;0.00181093379246725!GO:0043549;regulation of kinase activity;0.00181335184508504!GO:0000819;sister chromatid segregation;0.00182882994238228!GO:0008408;3'-5' exonuclease activity;0.00185278588570493!GO:0000070;mitotic sister chromatid segregation;0.00190364673804024!GO:0006275;regulation of DNA replication;0.00190364673804024!GO:0031124;mRNA 3'-end processing;0.00202090925801165!GO:0009116;nucleoside metabolic process;0.00202771233948594!GO:0000059;protein import into nucleus, docking;0.00204752534476489!GO:0008139;nuclear localization sequence binding;0.00210671496023724!GO:0003711;transcription elongation regulator activity;0.00210891894406739!GO:0051235;maintenance of localization;0.00215050273035451!GO:0045045;secretory pathway;0.00221888529144649!GO:0031252;leading edge;0.00225983520341087!GO:0006091;generation of precursor metabolites and energy;0.00229543290072354!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00229560994257731!GO:0045941;positive regulation of transcription;0.00231519830068217!GO:0030118;clathrin coat;0.00233923994839789!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00240268241368636!GO:0045047;protein targeting to ER;0.00240268241368636!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00249491305062713!GO:0006520;amino acid metabolic process;0.00255752427236054!GO:0016023;cytoplasmic membrane-bound vesicle;0.00258365002347416!GO:0033116;ER-Golgi intermediate compartment membrane;0.00259182641337806!GO:0030133;transport vesicle;0.00266236066922085!GO:0030134;ER to Golgi transport vesicle;0.00277957860926194!GO:0045892;negative regulation of transcription, DNA-dependent;0.00278540719129489!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00281738655348397!GO:0016197;endosome transport;0.0028397411986684!GO:0009893;positive regulation of metabolic process;0.00293909472441427!GO:0000922;spindle pole;0.00298801081442121!GO:0016126;sterol biosynthetic process;0.00300766453938421!GO:0042770;DNA damage response, signal transduction;0.00300766453938421!GO:0015980;energy derivation by oxidation of organic compounds;0.0030317417078895!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00314920139906072!GO:0045859;regulation of protein kinase activity;0.00314920139906072!GO:0046467;membrane lipid biosynthetic process;0.00318308705893195!GO:0031410;cytoplasmic vesicle;0.00319535282679344!GO:0031902;late endosome membrane;0.00321141168473109!GO:0003725;double-stranded RNA binding;0.00321141168473109!GO:0006289;nucleotide-excision repair;0.00324946636115405!GO:0030663;COPI coated vesicle membrane;0.00333535332558757!GO:0030126;COPI vesicle coat;0.00333535332558757!GO:0006595;polyamine metabolic process;0.00345558389018094!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00348464269599497!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00350121268952156!GO:0005876;spindle microtubule;0.00353110299649166!GO:0008234;cysteine-type peptidase activity;0.00353445199050188!GO:0006144;purine base metabolic process;0.00360667304366189!GO:0048487;beta-tubulin binding;0.00362093526937327!GO:0006338;chromatin remodeling;0.00362093526937327!GO:0019904;protein domain specific binding;0.00362093526937327!GO:0042613;MHC class II protein complex;0.00366852058412096!GO:0030127;COPII vesicle coat;0.00367020616098837!GO:0012507;ER to Golgi transport vesicle membrane;0.00367020616098837!GO:0000178;exosome (RNase complex);0.00367579007928459!GO:0042393;histone binding;0.00375612649683905!GO:0046966;thyroid hormone receptor binding;0.00381640230839923!GO:0006284;base-excision repair;0.00381640230839923!GO:0016272;prefoldin complex;0.00381640230839923!GO:0030518;steroid hormone receptor signaling pathway;0.00381640230839923!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00392791499947682!GO:0000725;recombinational repair;0.00421634923679572!GO:0000724;double-strand break repair via homologous recombination;0.00421634923679572!GO:0030433;ER-associated protein catabolic process;0.00428617401938936!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.00428617401938936!GO:0032940;secretion by cell;0.00438950222440165!GO:0019752;carboxylic acid metabolic process;0.00452729174047379!GO:0006007;glucose catabolic process;0.00457215390984442!GO:0042113;B cell activation;0.00463517642257679!GO:0005788;endoplasmic reticulum lumen;0.00466052421881504!GO:0046489;phosphoinositide biosynthetic process;0.00473834026334531!GO:0000175;3'-5'-exoribonuclease activity;0.0047807674766407!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0048956366027341!GO:0016584;nucleosome positioning;0.00499121868216308!GO:0031570;DNA integrity checkpoint;0.0050760787863409!GO:0051087;chaperone binding;0.00509915190238163!GO:0046649;lymphocyte activation;0.00511064674803556!GO:0016491;oxidoreductase activity;0.00515419717398248!GO:0006818;hydrogen transport;0.00515419717398248!GO:0009112;nucleobase metabolic process;0.00518434912841963!GO:0030137;COPI-coated vesicle;0.00535243063494905!GO:0046474;glycerophospholipid biosynthetic process;0.00536901362613184!GO:0006082;organic acid metabolic process;0.00545270194465344!GO:0045893;positive regulation of transcription, DNA-dependent;0.00566418216396605!GO:0005853;eukaryotic translation elongation factor 1 complex;0.00573681447459155!GO:0006984;ER-nuclear signaling pathway;0.0057434928611533!GO:0043022;ribosome binding;0.00602493028065863!GO:0000781;chromosome, telomeric region;0.00603281951542479!GO:0051539;4 iron, 4 sulfur cluster binding;0.00609052807159879!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00611109526100569!GO:0051053;negative regulation of DNA metabolic process;0.0061451807251997!GO:0007010;cytoskeleton organization and biogenesis;0.0062336157442909!GO:0007017;microtubule-based process;0.00623688315834428!GO:0031325;positive regulation of cellular metabolic process;0.00624912181072897!GO:0031123;RNA 3'-end processing;0.00628395244295573!GO:0022415;viral reproductive process;0.00633512021825887!GO:0008637;apoptotic mitochondrial changes;0.00633512021825887!GO:0009124;nucleoside monophosphate biosynthetic process;0.00652221878726237!GO:0009123;nucleoside monophosphate metabolic process;0.00652221878726237!GO:0004003;ATP-dependent DNA helicase activity;0.00654210738736385!GO:0043601;nuclear replisome;0.0066164509512957!GO:0030894;replisome;0.0066164509512957!GO:0015992;proton transport;0.00669325899441093!GO:0030176;integral to endoplasmic reticulum membrane;0.00694809778667893!GO:0051540;metal cluster binding;0.00701260300762573!GO:0051536;iron-sulfur cluster binding;0.00701260300762573!GO:0000339;RNA cap binding;0.0072049118913526!GO:0035258;steroid hormone receptor binding;0.00723492757197004!GO:0006376;mRNA splice site selection;0.0075478074500499!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0075478074500499!GO:0043284;biopolymer biosynthetic process;0.00772154628698322!GO:0005669;transcription factor TFIID complex;0.00782778691354696!GO:0032259;methylation;0.00794672435168869!GO:0000209;protein polyubiquitination;0.00802569290982778!GO:0003887;DNA-directed DNA polymerase activity;0.0081301644895638!GO:0050851;antigen receptor-mediated signaling pathway;0.00827375612874551!GO:0004536;deoxyribonuclease activity;0.00856640268441145!GO:0030521;androgen receptor signaling pathway;0.00861303332525762!GO:0007004;telomere maintenance via telomerase;0.00861577985204329!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.00863832250382165!GO:0043492;ATPase activity, coupled to movement of substances;0.00866321283188178!GO:0005832;chaperonin-containing T-complex;0.00918268533447013!GO:0005663;DNA replication factor C complex;0.00922458024160672!GO:0006355;regulation of transcription, DNA-dependent;0.00930388784199161!GO:0022890;inorganic cation transmembrane transporter activity;0.00939242100516503!GO:0032507;maintenance of cellular protein localization;0.00939260133123921!GO:0030968;unfolded protein response;0.00956507872891272!GO:0006695;cholesterol biosynthetic process;0.00957887728910176!GO:0008610;lipid biosynthetic process;0.00966814118307888!GO:0045069;regulation of viral genome replication;0.00966814118307888!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0100442921937705!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0100723454483282!GO:0006643;membrane lipid metabolic process;0.0101992340219944!GO:0000287;magnesium ion binding;0.0102550733704413!GO:0051098;regulation of binding;0.0105680237596798!GO:0004722;protein serine/threonine phosphatase activity;0.0107816248747176!GO:0044450;microtubule organizing center part;0.010795139593829!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0108543075728093!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.011242608972721!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0114037858417785!GO:0015002;heme-copper terminal oxidase activity;0.0114037858417785!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0114037858417785!GO:0004129;cytochrome-c oxidase activity;0.0114037858417785!GO:0044454;nuclear chromosome part;0.0115342763224025!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0118661474909651!GO:0043130;ubiquitin binding;0.0120663806458815!GO:0032182;small conjugating protein binding;0.0120663806458815!GO:0005791;rough endoplasmic reticulum;0.0121160101821961!GO:0043414;biopolymer methylation;0.0121555310931312!GO:0043086;negative regulation of catalytic activity;0.0124706382001217!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0125315368178453!GO:0019783;small conjugating protein-specific protease activity;0.0125880459408856!GO:0009451;RNA modification;0.0126463610709039!GO:0016791;phosphoric monoester hydrolase activity;0.0126463610709039!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0126463610709039!GO:0008287;protein serine/threonine phosphatase complex;0.0127964715288005!GO:0046983;protein dimerization activity;0.0130114034505741!GO:0030125;clathrin vesicle coat;0.0137665991916041!GO:0030665;clathrin coated vesicle membrane;0.0137665991916041!GO:0051051;negative regulation of transport;0.0139732445711171!GO:0005774;vacuolar membrane;0.0139732445711171!GO:0045185;maintenance of protein localization;0.0141369375301533!GO:0005874;microtubule;0.0143139773322924!GO:0006378;mRNA polyadenylation;0.0147402204634925!GO:0009161;ribonucleoside monophosphate metabolic process;0.0150687788830074!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0150687788830074!GO:0000910;cytokinesis;0.0155946417106192!GO:0006278;RNA-dependent DNA replication;0.0155994467992962!GO:0018193;peptidyl-amino acid modification;0.0156164676200956!GO:0004576;oligosaccharyl transferase activity;0.015650737059181!GO:0000086;G2/M transition of mitotic cell cycle;0.0156700767376552!GO:0000738;DNA catabolic process, exonucleolytic;0.0162057868335818!GO:0004843;ubiquitin-specific protease activity;0.0162057868335818!GO:0008022;protein C-terminus binding;0.0162714865264342!GO:0031577;spindle checkpoint;0.0162735254795654!GO:0008047;enzyme activator activity;0.0166407890500955!GO:0016788;hydrolase activity, acting on ester bonds;0.0167804264348252!GO:0004860;protein kinase inhibitor activity;0.0168861759095767!GO:0006368;RNA elongation from RNA polymerase II promoter;0.016913671147188!GO:0033157;regulation of intracellular protein transport;0.0170305932664044!GO:0042306;regulation of protein import into nucleus;0.0170305932664044!GO:0000077;DNA damage checkpoint;0.0171295405089004!GO:0006672;ceramide metabolic process;0.0175377502001917!GO:0000726;non-recombinational repair;0.0179943276884082!GO:0004540;ribonuclease activity;0.0180983466494393!GO:0019079;viral genome replication;0.0186959347968056!GO:0043407;negative regulation of MAP kinase activity;0.018780748056077!GO:0005765;lysosomal membrane;0.018797341660929!GO:0019210;kinase inhibitor activity;0.0189519802627905!GO:0006497;protein amino acid lipidation;0.019540224153619!GO:0006607;NLS-bearing substrate import into nucleus;0.0195749116789168!GO:0046982;protein heterodimerization activity;0.0196113043283685!GO:0000118;histone deacetylase complex;0.0196156816857348!GO:0006308;DNA catabolic process;0.0196815447321437!GO:0006354;RNA elongation;0.0197395317114632!GO:0005096;GTPase activator activity;0.0197620341196744!GO:0008156;negative regulation of DNA replication;0.0199059689188978!GO:0051656;establishment of organelle localization;0.0199266263175213!GO:0006096;glycolysis;0.020221144234827!GO:0008017;microtubule binding;0.020221144234827!GO:0051651;maintenance of cellular localization;0.0202746034677967!GO:0016790;thiolester hydrolase activity;0.0204757930972169!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0205795185564833!GO:0009303;rRNA transcription;0.0205847500021248!GO:0004221;ubiquitin thiolesterase activity;0.0208208033240543!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0208248670928646!GO:0019843;rRNA binding;0.0209455297940877!GO:0031625;ubiquitin protein ligase binding;0.0209941633024445!GO:0030119;AP-type membrane coat adaptor complex;0.0209941633024445!GO:0007265;Ras protein signal transduction;0.0211293937655465!GO:0050852;T cell receptor signaling pathway;0.0211674537277766!GO:0031647;regulation of protein stability;0.0211674537277766!GO:0008250;oligosaccharyl transferase complex;0.0211674537277766!GO:0019900;kinase binding;0.0214974815353096!GO:0005869;dynactin complex;0.0217271388338117!GO:0006519;amino acid and derivative metabolic process;0.0219046464401714!GO:0030522;intracellular receptor-mediated signaling pathway;0.0223243792293903!GO:0046365;monosaccharide catabolic process;0.022699991699576!GO:0009081;branched chain family amino acid metabolic process;0.0229508237423364!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0240323031480187!GO:0045039;protein import into mitochondrial inner membrane;0.0240323031480187!GO:0051287;NAD binding;0.0243875142203025!GO:0016301;kinase activity;0.0245006843985898!GO:0000792;heterochromatin;0.0249622750557534!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0249752229838679!GO:0008180;signalosome;0.0251515628763125!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.025322933889911!GO:0043433;negative regulation of transcription factor activity;0.0253311126787701!GO:0000096;sulfur amino acid metabolic process;0.0254809613116401!GO:0030262;apoptotic nuclear changes;0.0258177675683492!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0261501611446066!GO:0000152;nuclear ubiquitin ligase complex;0.0261755604051765!GO:0016311;dephosphorylation;0.0262026249238905!GO:0050178;phenylpyruvate tautomerase activity;0.0264958101505033!GO:0051224;negative regulation of protein transport;0.0270040184615551!GO:0030695;GTPase regulator activity;0.0271815857463563!GO:0008538;proteasome activator activity;0.0282452211330031!GO:0007253;cytoplasmic sequestering of NF-kappaB;0.0282960377941832!GO:0051101;regulation of DNA binding;0.0293084694731509!GO:0005784;translocon complex;0.0293291849620455!GO:0044438;microbody part;0.0296039514053723!GO:0044439;peroxisomal part;0.0296039514053723!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.029611321949642!GO:0033367;protein localization in mast cell secretory granule;0.029611321949642!GO:0033365;protein localization in organelle;0.029611321949642!GO:0033371;T cell secretory granule organization and biogenesis;0.029611321949642!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.029611321949642!GO:0033375;protease localization in T cell secretory granule;0.029611321949642!GO:0042629;mast cell granule;0.029611321949642!GO:0033377;maintenance of protein localization in T cell secretory granule;0.029611321949642!GO:0033364;mast cell secretory granule organization and biogenesis;0.029611321949642!GO:0033380;granzyme B localization in T cell secretory granule;0.029611321949642!GO:0033379;maintenance of protease localization in T cell secretory granule;0.029611321949642!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.029611321949642!GO:0033368;protease localization in mast cell secretory granule;0.029611321949642!GO:0033366;protein localization in secretory granule;0.029611321949642!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.029611321949642!GO:0033374;protein localization in T cell secretory granule;0.029611321949642!GO:0019901;protein kinase binding;0.0296808400801472!GO:0006506;GPI anchor biosynthetic process;0.0299747060472439!GO:0046128;purine ribonucleoside metabolic process;0.030182145018044!GO:0042278;purine nucleoside metabolic process;0.030182145018044!GO:0016408;C-acyltransferase activity;0.0303120458631742!GO:0008276;protein methyltransferase activity;0.0303629118499844!GO:0030041;actin filament polymerization;0.0303629118499844!GO:0032984;macromolecular complex disassembly;0.0303629118499844!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0307432030325145!GO:0010257;NADH dehydrogenase complex assembly;0.0307432030325145!GO:0033108;mitochondrial respiratory chain complex assembly;0.0307432030325145!GO:0030027;lamellipodium;0.0307815776003676!GO:0044437;vacuolar part;0.0309757919720702!GO:0004721;phosphoprotein phosphatase activity;0.0315025181131622!GO:0033170;DNA-protein loading ATPase activity;0.0315754267048856!GO:0003689;DNA clamp loader activity;0.0315754267048856!GO:0006400;tRNA modification;0.0316459449880961!GO:0030130;clathrin coat of trans-Golgi network vesicle;0.0316459449880961!GO:0012510;trans-Golgi network transport vesicle membrane;0.0316459449880961!GO:0045947;negative regulation of translational initiation;0.0319411391073466!GO:0046112;nucleobase biosynthetic process;0.0321466395704961!GO:0046519;sphingoid metabolic process;0.0321559402378686!GO:0035267;NuA4 histone acetyltransferase complex;0.0323911644838635!GO:0018196;peptidyl-asparagine modification;0.0325000604172461!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0325000604172461!GO:0000793;condensed chromosome;0.0329508113635781!GO:0051220;cytoplasmic sequestering of protein;0.0330928570894143!GO:0006415;translational termination;0.0331814215258482!GO:0042990;regulation of transcription factor import into nucleus;0.0331850584451124!GO:0042991;transcription factor import into nucleus;0.0331850584451124!GO:0030374;ligand-dependent nuclear receptor transcription coactivator activity;0.0340578414301047!GO:0006596;polyamine biosynthetic process;0.0340752604592964!GO:0019320;hexose catabolic process;0.0341894285568195!GO:0005652;nuclear lamina;0.0346900085898019!GO:0045936;negative regulation of phosphate metabolic process;0.0348401224839533!GO:0043189;H4/H2A histone acetyltransferase complex;0.0348727160104324!GO:0008097;5S rRNA binding;0.0351061985531039!GO:0008624;induction of apoptosis by extracellular signals;0.0351082938927348!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0358247803106201!GO:0046823;negative regulation of nucleocytoplasmic transport;0.0361068580955388!GO:0030131;clathrin adaptor complex;0.0367901461462912!GO:0006505;GPI anchor metabolic process;0.0367901461462912!GO:0004523;ribonuclease H activity;0.0376826384985529!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0376946965472532!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0390538439106989!GO:0004748;ribonucleoside-diphosphate reductase activity;0.039246808019601!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.039246808019601!GO:0031903;microbody membrane;0.039460396174038!GO:0005778;peroxisomal membrane;0.039460396174038!GO:0002757;immune response-activating signal transduction;0.0396485477796132!GO:0050662;coenzyme binding;0.0398087893931475!GO:0046164;alcohol catabolic process;0.0399064608113837!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0399064608113837!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0399064608113837!GO:0009126;purine nucleoside monophosphate metabolic process;0.0399064608113837!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0399064608113837!GO:0050792;regulation of viral reproduction;0.04002542843424!GO:0009083;branched chain family amino acid catabolic process;0.0408939284451277!GO:0031371;ubiquitin conjugating enzyme complex;0.0408949116392165!GO:0003756;protein disulfide isomerase activity;0.0411381647147177!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0411381647147177!GO:0005092;GDP-dissociation inhibitor activity;0.0411381647147177!GO:0007034;vacuolar transport;0.0413537592784644!GO:0019238;cyclohydrolase activity;0.041373314452935!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0413910072049133!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.0414616917150539!GO:0046979;TAP2 binding;0.041780460874195!GO:0046977;TAP binding;0.041780460874195!GO:0046978;TAP1 binding;0.041780460874195!GO:0007094;mitotic cell cycle spindle assembly checkpoint;0.0426759827695176!GO:0006740;NADPH regeneration;0.0427250326531556!GO:0006098;pentose-phosphate shunt;0.0427250326531556!GO:0019902;phosphatase binding;0.0429146409999264!GO:0030508;thiol-disulfide exchange intermediate activity;0.0431689451452335!GO:0006406;mRNA export from nucleus;0.0433192880623176!GO:0043621;protein self-association;0.0434965934767881!GO:0051090;regulation of transcription factor activity;0.0435805137910534!GO:0044262;cellular carbohydrate metabolic process;0.0438098592997664!GO:0042994;cytoplasmic sequestering of transcription factor;0.0445962225310937!GO:0048524;positive regulation of viral reproduction;0.0446637822805585!GO:0008652;amino acid biosynthetic process;0.0446637822805585!GO:0015036;disulfide oxidoreductase activity;0.0448489827854038!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0448578157404731!GO:0008537;proteasome activator complex;0.0451142262242738!GO:0051059;NF-kappaB binding;0.0452925879022527!GO:0043241;protein complex disassembly;0.0453141780510222!GO:0016407;acetyltransferase activity;0.0456125385433392!GO:0000123;histone acetyltransferase complex;0.0463086249078376!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0466876342981992!GO:0046426;negative regulation of JAK-STAT cascade;0.0470196491913894!GO:0004520;endodeoxyribonuclease activity;0.0471740287177083!GO:0017134;fibroblast growth factor binding;0.0472960306507426!GO:0019318;hexose metabolic process;0.0474343686814562!GO:0006778;porphyrin metabolic process;0.0477077910096188!GO:0033013;tetrapyrrole metabolic process;0.0477077910096188!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.0479268314169801!GO:0006644;phospholipid metabolic process;0.0484839420963527!GO:0006458;'de novo' protein folding;0.0484839420963527!GO:0051084;'de novo' posttranslational protein folding;0.0484839420963527!GO:0042158;lipoprotein biosynthetic process;0.0492720533081825!GO:0016569;covalent chromatin modification;0.0494290014744927!GO:0003747;translation release factor activity;0.0497284639345244!GO:0008079;translation termination factor activity;0.0497284639345244!GO:0005083;small GTPase regulator activity;0.049748649392605
|sample_id=10840
|sample_note=
|sample_sex=female
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_tissue=blood
|top_motifs=POU2F1..3:2.86225114448;PAX6:2.12931736635;POU5F1:2.04423357147;HOXA9_MEIS1:1.87547667542;IRF1,2:1.54648651776;DMAP1_NCOR{1,2}_SMARC:1.53070719488;NFY{A,B,C}:1.52100213269;IRF7:1.45505876856;CDX1,2,4:1.44033814354;E2F1..5:1.33667351923;PDX1:1.24089425439;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.23078233898;MYB:1.20890857379;NFKB1_REL_RELA:1.14663492546;MYOD1:1.13706961699;HIF1A:1.08286765313;ELK1,4_GABP{A,B1}:1.06757890918;RORA:1.00757208022;ELF1,2,4:0.985128015364;RUNX1..3:0.982464847837;FOXA2:0.975616382536;PBX1:0.952814517455;NKX2-1,4:0.887960121606;PAX8:0.865202601532;ATF4:0.863884098313;NKX6-1,2:0.82866793376;BREu{core}:0.725241684991;RBPJ:0.71509989508;SPI1:0.701162795952;ZNF143:0.700116681668;PAX3,7:0.699220110373;ZBTB16:0.693504157569;YY1:0.650510379519;LMO2:0.642222021172;OCT4_SOX2{dimer}:0.635008405951;NRF1:0.609914356248;CUX2:0.605971994686;bHLH_family:0.604289134814;TGIF1:0.597306775314;POU1F1:0.543741050259;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.500708767675;EVI1:0.477001627604;SPIB:0.41453830225;GATA6:0.405764481845;AIRE:0.403957164732;NFIX:0.39959880829;FOXP3:0.377924093021;IKZF2:0.374046140237;ZEB1:0.334453078523;ATF5_CREB3:0.332787051086;NR5A1,2:0.273778270033;AHR_ARNT_ARNT2:0.257566821602;TLX2:0.234749837988;ETS1,2:0.230903264124;SOX{8,9,10}:0.2208785132;RFX2..5_RFXANK_RFXAP:0.194534053075;ZNF148:0.17870722861;HES1:0.152379841299;CREB1:0.145842703009;HBP1_HMGB_SSRP1_UBTF:0.144698039365;POU3F1..4:0.129370940878;PRRX1,2:0.127678084322;GFI1:0.117529433838;SNAI1..3:0.116209855445;PAX2:0.077449280595;PPARG:0.0668604327589;FOXN1:0.0624922712865;CDC5L:0.0220911049539;NANOG{mouse}:0.011454890754;SOX5:0.00469431050001;NKX2-2,8:0.00352742260944;FOX{F1,F2,J1}:0.00191253612485;MEF2{A,B,C,D}:-0.00518922230694;VSX1,2:-0.00936976944096;DBP:-0.0356229741339;LEF1_TCF7_TCF7L1,2:-0.0508880866071;FOXP1:-0.112851156403;ARID5B:-0.143939228513;HOX{A6,A7,B6,B7}:-0.154067222281;FOSL2:-0.167668901774;STAT5{A,B}:-0.169868946094;TBP:-0.182126823804;HSF1,2:-0.183608880192;ZNF384:-0.186396364863;RXR{A,B,G}:-0.191262891749;CRX:-0.201772961277;PAX4:-0.202628749425;CEBPA,B_DDIT3:-0.208771036482;FOXQ1:-0.210691636723;ESRRA:-0.22554460113;PITX1..3:-0.228170253383;BPTF:-0.233104491092;HNF4A_NR2F1,2:-0.235300695485;SMAD1..7,9:-0.24381005928;SOX17:-0.244203528988;NFE2:-0.255778831115;ESR1:-0.278469086453;POU6F1:-0.281878589674;NFATC1..3:-0.290083410213;EBF1:-0.297597197168;TFDP1:-0.315285090186;HNF1A:-0.329030898696;ATF6:-0.330826709697;SREBF1,2:-0.349656095974;HMGA1,2:-0.357473979254;JUN:-0.380182894655;UFEwm:-0.391858304056;ATF2:-0.392008636577;RXRA_VDR{dimer}:-0.396932994154;ONECUT1,2:-0.404657275293;AR:-0.409426149481;TEF:-0.4124461808;FOXO1,3,4:-0.42406523614;HOX{A5,B5}:-0.43460321116;ZFP161:-0.437358958266;TFAP4:-0.447591437406;TOPORS:-0.460973917818;NR6A1:-0.473789584312;MYFfamily:-0.511487174673;PRDM1:-0.511689869509;GCM1,2:-0.516101880096;HAND1,2:-0.52482444075;SPZ1:-0.536258809966;FOS_FOS{B,L1}_JUN{B,D}:-0.554447201904;STAT2,4,6:-0.55689671594;RFX1:-0.57490529002;GFI1B:-0.581708192848;BACH2:-0.588961059788;NHLH1,2:-0.600154489759;NFIL3:-0.612051060487;HOX{A4,D4}:-0.628802879124;MAFB:-0.638835842802;NKX3-2:-0.650900704277;TAL1_TCF{3,4,12}:-0.668567373859;ALX4:-0.674085030613;STAT1,3:-0.716069728703;TP53:-0.723095308116;EGR1..3:-0.730558751139;EN1,2:-0.738798699961;SOX2:-0.776774916017;FOX{D1,D2}:-0.786161896983;PATZ1:-0.789177195788;RREB1:-0.814574082709;GLI1..3:-0.827130822024;REST:-0.837437917178;MTE{core}:-0.838872882001;HLF:-0.86602632347;NKX3-1:-0.873975242897;PAX5:-0.874320546956;SRF:-0.898388648169;ADNP_IRX_SIX_ZHX:-0.953313242029;GATA4:-0.961239901754;T:-1.01685536879;HIC1:-1.02810191911;MED-1{core}:-1.02812221057;ZNF238:-1.02902639847;NANOG:-1.03061420954;NFE2L2:-1.03753710539;MTF1:-1.06051923416;FOXL1:-1.08945693962;GTF2A1,2:-1.12155946682;ALX1:-1.12963105082;PAX1,9:-1.12993654887;ZIC1..3:-1.13775479452;IKZF1:-1.13783370407;LHX3,4:-1.15625724399;GZF1:-1.16746990872;MYBL2:-1.17598190064;XBP1:-1.18989665209;EP300:-1.20891386243;MZF1:-1.2177062385;SP1:-1.23420438168;TBX4,5:-1.2559353353;FOXD3:-1.26786782295;HMX1:-1.29323806928;NR1H4:-1.30978970559;GTF2I:-1.31759260776;ZBTB6:-1.33535716242;NKX2-3_NKX2-5:-1.34639119422;ZNF423:-1.34892427995;NR3C1:-1.36267289887;TFAP2B:-1.37705689226;KLF4:-1.40461022524;FOXM1:-1.42554028359;NFE2L1:-1.44427150881;MAZ:-1.44891837647;XCPE1{core}:-1.48557028897;TFAP2{A,C}:-1.54434990668;TFCP2:-1.61323651831;TEAD1:-1.61868089366;TLX1..3_NFIC{dimer}:-1.70308564928;FOX{I1,J2}:-1.73202205738
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10840-111E3;search_select_hide=table117:FF:10840-111E3
}}
}}

Latest revision as of 15:08, 3 June 2020

Name:plasma cell leukemia cell line:ARH-77
Species:Human (Homo sapiens)
Library ID:CNhs12807
Sample type:cell lines
Genomic View: UCSC
RefEX:Specific genes
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueblood
dev stageNA
sexfemale
age33
cell typeplasma cell
cell lineARH-77
companyATCC
collaborationFANTOM5 OSC CORE (contact: Al Forrest)
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00004916
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs12807 CAGE DRX007985 DRR008857
Accession ID Hg19

Library idBAMCTSS
CNhs12807 DRZ000282 DRZ001667
Accession ID Hg38

Library idBAMCTSS
CNhs12807 DRZ011632 DRZ013017
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.101
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0.0182
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma0.548
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
C110-leukemia-chronic-Eosinophils-acute-Whole-CD34-Lymphatic0
C111-medulla-lung-trachea-testis-caudate-epididymis-throat0
C112-gastric-pancreas-temporal-duodenum-small-extraskeletal-adrenal0
C113-thyroid-throat-lung-lymph-small-colon-trachea0
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C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12807

Jaspar motifP-value
MA0002.20.0139
MA0003.10.522
MA0004.10.0129
MA0006.10.172
MA0007.10.702
MA0009.10.612
MA0014.10.937
MA0017.10.486
MA0018.20.593
MA0019.10.967
MA0024.11.50395e-7
MA0025.10.502
MA0027.10.816
MA0028.12.53444e-5
MA0029.10.327
MA0030.10.106
MA0031.10.603
MA0035.20.113
MA0038.10.133
MA0039.20.964
MA0040.10.11
MA0041.10.227
MA0042.10.466
MA0043.10.949
MA0046.10.252
MA0047.20.852
MA0048.10.936
MA0050.11.39552e-19
MA0051.11.29241e-14
MA0052.10.401
MA0055.10.157
MA0057.10.767
MA0058.10.00846
MA0059.12.43636e-4
MA0060.14.98294e-17
MA0061.13.37274e-9
MA0062.22.02209e-8
MA0065.20.0671
MA0066.10.706
MA0067.10.478
MA0068.10.257
MA0069.10.927
MA0070.10.762
MA0071.10.834
MA0072.10.12
MA0073.10.595
MA0074.10.644
MA0076.15.13093e-8
MA0077.10.446
MA0078.10.107
MA0079.20.32
MA0080.22.99287e-5
MA0081.10.0209
MA0083.10.416
MA0084.10.105
MA0087.10.0903
MA0088.10.0274
MA0090.11.91167e-5
MA0091.10.856
MA0092.10.521
MA0093.10.0106
MA0099.20.00131
MA0100.10.0561
MA0101.11.34007e-7
MA0102.20.354
MA0103.10.0204
MA0104.21.04975e-4
MA0105.14.25612e-8
MA0106.10.903
MA0107.13.70235e-8
MA0108.20.101
MA0111.10.522
MA0112.20.927
MA0113.10.307
MA0114.10.197
MA0115.10.272
MA0116.10.00101
MA0117.10.724
MA0119.10.421
MA0122.10.387
MA0124.10.384
MA0125.10.55
MA0131.10.136
MA0135.10.529
MA0136.13.89651e-8
MA0137.20.425
MA0138.20.973
MA0139.10.231
MA0140.10.00625
MA0141.10.431
MA0142.10.194
MA0143.10.287
MA0144.10.0755
MA0145.10.128
MA0146.10.727
MA0147.14.32092e-5
MA0148.10.268
MA0149.10.238
MA0150.10.546
MA0152.10.172
MA0153.10.0943
MA0154.10.012
MA0155.10.556
MA0156.11.7092e-9
MA0157.10.924
MA0159.10.218
MA0160.10.375
MA0162.10.492
MA0163.12.8517e-8
MA0164.10.262
MA0258.10.514
MA0259.10.0129



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs12807

Novel motifP-value
10.143
100.0245
1000.216
1010.457
1020.473
1030.332
1040.579
1050.479
1060.801
1070.313
1080.938
1090.0963
110.532
1100.613
1110.044
1120.888
1130.858
1140.726
1150.5
1160.723
1170.0313
1180.56
1190.395
120.674
1200.871
1210.195
1220.344
1230.202
1240.019
1250.559
1260.132
1270.561
1280.145
1290.294
130.0447
1300.257
1310.52
1320.121
1330.258
1340.558
1350.642
1360.16
1370.58
1380.558
1390.846
140.828
1400.203
1410.00515
1420.791
1430.0276
1440.458
1450.758
1460.931
1470.263
1480.172
1490.389
150.0592
1500.859
1510.161
1520.0571
1530.795
1540.617
1550.108
1560.764
1570.214
1580.412
1590.332
160.356
1600.418
1610.0374
1620.558
1630.948
1640.958
1650.912
1660.253
1670.134
1680.719
1690.216
170.913
180.419
190.496
20.133
200.106
210.44
220.499
230.207
240.0491
250.0622
260.152
270.92
280.561
290.00351
30.446
300.0761
310.794
320.189
330.3
340.519
350.231
360.0404
370.723
380.446
390.247
40.0381
400.114
410.492
420.263
430.455
440.213
450.261
460.454
470.128
480.273
490.159
50.637
500.741
510.697
520.186
530.777
540.283
550.184
560.941
570.798
580.07
590.657
60.988
600.933
610.229
620.131
630.59
640.773
650.691
664.18633e-5
670.491
680.229
690.83
70.128
700.789
710.0308
720.186
730.56
740.961
750.0185
760.153
770.0221
780.162
790.689
80.556
800.257
810.264
820.365
830.096
840.696
850.308
860.368
870.088
880.697
890.354
90.425
900.309
910.505
920.711
930.419
940.928
950.00716
960.8
970.179
980.832
990.0575



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs12807


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000151 (secretory cell)
0002371 (somatic cell)
0000542 (lymphocyte)
0000219 (motile cell)
0000945 (lymphocyte of B lineage)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0002242 (nucleate cell)
0000255 (eukaryotic cell)
0000946 (antibody secreting cell)
0000786 (plasma cell)

FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0101035 (hematopoietic cell line sample)
0100773 (lymphoblastoid cell line sample)
0101522 (B-lymphocyte cell line sample)
0102062 (B-lymphoblastoid cell line sample)
0102992 (ARH-77 cell sample)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000051 (common lymphoid progenitor)
CL:0000954 (small pre-B-II cell)

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