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Coexpression cluster:C1293: Difference between revisions

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|full_id=C1293_CD14_CD14CD16_Basophils_Mast_Eosinophils_Neutrophils_Peripheral
|full_id=C1293_CD14_CD14CD16_Basophils_Mast_Eosinophils_Neutrophils_Peripheral
|id=C1293
|id=C1293
|ontology_enrichment_celltype=CL:0000766!7.38e-29!76;CL:0002057!8.98e-28!42;CL:0000860!1.26e-26!45;CL:0000557!4.98e-25!71;CL:0000839!2.82e-24!70;CL:0002009!2.18e-22!65;CL:0002194!9.34e-22!63;CL:0000576!9.34e-22!63;CL:0000040!9.34e-22!63;CL:0000559!9.34e-22!63;CL:0000738!2.20e-18!140;CL:0000763!2.46e-17!112;CL:0000049!2.46e-17!112;CL:0002031!8.73e-13!124;CL:0000037!4.04e-12!172;CL:0000566!4.04e-12!172;CL:0000988!6.53e-12!182;CL:0002087!1.71e-11!119;CL:0002032!1.83e-10!165;CL:0000837!1.83e-10!165;CL:0002393!2.07e-07!9;CL:0002397!2.07e-07!9
|ontology_enrichment_celltype=CL:0000860!1.93e-82!42;CL:0002057!1.93e-82!42;CL:0000766!6.52e-76!72;CL:0000473!1.10e-73!48;CL:0000234!1.10e-73!48;CL:0000839!7.61e-62!66;CL:0000557!1.05e-60!67;CL:0002194!9.74e-59!59;CL:0000576!9.74e-59!59;CL:0000040!9.74e-59!59;CL:0000559!9.74e-59!59;CL:0002009!2.25e-56!61;CL:0000738!2.07e-48!136;CL:0000763!4.16e-45!108;CL:0000049!4.16e-45!108;CL:0002087!1.71e-38!115;CL:0000325!5.47e-38!87;CL:0002031!9.16e-38!120;CL:0000037!7.04e-37!168;CL:0000566!7.04e-37!168;CL:0000988!4.79e-34!177;CL:0002032!1.62e-33!161;CL:0000837!1.62e-33!161;CL:0002393!2.01e-19!9;CL:0002397!2.01e-19!9;CL:0000094!1.72e-12!8;CL:0000134!7.35e-11!354;CL:0002320!2.62e-10!361;CL:0000081!1.02e-08!11;CL:0000219!2.14e-08!386;CL:0000875!1.32e-07!3;CL:0002396!1.32e-07!3;CL:0000767!2.81e-07!3;CL:0000226!6.88e-07!3;CL:0000842!6.88e-07!3
|ontology_enrichment_disease=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0002390!1.37e-26!102;UBERON:0003061!1.37e-26!102;UBERON:0002371!7.98e-23!80;UBERON:0001474!1.72e-22!86;UBERON:0002193!2.40e-21!112;UBERON:0004765!1.78e-18!101;UBERON:0001434!1.78e-18!101;UBERON:0002405!1.28e-12!115;UBERON:0007023!1.70e-11!115;UBERON:0003081!2.10e-09!216;UBERON:0002204!1.05e-07!167;UBERON:0000178!9.97e-07!15;UBERON:0000179!9.97e-07!15;UBERON:0000463!9.97e-07!15
|ontology_enrichment_uberon=UBERON:0002390!3.31e-61!98;UBERON:0003061!3.31e-61!98;UBERON:0002193!5.11e-58!108;UBERON:0002371!2.86e-56!76;UBERON:0001474!4.77e-51!82;UBERON:0002405!4.13e-49!93;UBERON:0004765!3.64e-45!90;UBERON:0001434!3.87e-39!100;UBERON:0003081!1.75e-26!203;UBERON:0002204!1.90e-18!167;UBERON:0000926!5.48e-12!315;UBERON:0004120!5.48e-12!315;UBERON:0006603!5.48e-12!315;UBERON:0002384!4.15e-10!371;UBERON:0000178!5.21e-09!15;UBERON:0000179!5.21e-09!15;UBERON:0000463!5.21e-09!15
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06,0.076236,0.444489,0.31161,0.361651,0.0953991,0.319245,0.603631,0.0650516,0.0560806,0.390908,0.0773818,0.115736,0.662745,0.229952,0.205891,0.207936,0.454529,0.0563868,0.473176,0.268235,0.0761868,0.167255,0.107028,0.267379,0.443026,0.387018,0.343977,0.244992,0.632847,0.417985,0.491614,0.146453,0.315229,0.157053,0.332022,0.557852,0.273582,0.262915,0.306556,0.26147,0.170005,0.523331,0.491788,0.092369,0.18076,0.692556,0.248113,0.148878,0.206465,0.240599,0.245625,0.0313577,0.696152,0.100989,0.188919,0.0975693,0.119835,0.145322,0.178533,0.267392,0.0668831,0.142859,0.477403,0.504405,0.358495,0.387334,0.494914,0.224219,0.347904,0.324262,0.471029,0.111827,0.0929171,0.63152,0.118035,0.319902,0.510835,0.137556,0.0922978,0.49748,0.0699003,0.235435,0.31953,0.1177,0.314983,0.370285,0.388777,0.204831,0.130161,0.205669,0.0963721,0.182511,0.369139,0.145449,0.0892237,0.208284,0.135613,0.401189,0.283386,0.0739625,0.0335664,0.0879809,0.104922,0.215434,0.177269,0.31512,0.198881,0.394164,0.111068,0.4137,0.146194,0.491435,0.281527,0.35188,0.3889,0.192889,0.547162,0.316041,0.565635,0.280212,0.121421,0.346061,0.275075,0.167651,0.287361,0.138613,0.175356,0.116846,0.267784,0.278571,0.185281,0.286026,0.31159,0.349805,0.255609,0.404239,0.439697,0.493192,0.223892,0.160738,0.193111,0.213489,0.212611,0.338443,0.319005,0.180695,0.45842,0.436073,0.261316,0.189596,0.448839,0.196587,0.213353,0.0504588,0.307626,0.173101,0.525576,0.0525138,0.341713,0.156156,0.33569,0.288104,0.526446,0.761719,0.114697,0.111558,0.324956,0.388835,0.408751,0.281184,0.305648,0.070868,0.654476,0.245,0.0850317,0.249379,0.661446,0.60218,0.696439,0.0219639,0.409327,0.466607,0.322166,0.603176,0.670776,0.334228,0.355968,0.636386,0.226461,0.27962,0.616927,0.518189,0.15467,0.677416,0.47184,0.628346,0.737948,0.750579,0.689958,0.435483,0.0621465,0.121336,0.402631,0.768239,0.573004,0.623606,0.488239,0.410034,0.799242,0.2667,0.494578,0.301433,0.711296,0.148546,0.509735,0.727698,0.198334,0.717449,0.449761,0.116888,0.427531,0.353735,0.629087,0.743042,0.668933,0.297082,0.304061,0.342233,0.746016,0.399871,0.607585,0.369581,0.37236,0.195513,0.518149,0.343078,0.36546,0.360788,0.368898,0.510705,0.447298,0.670481,0.576455,0.251998,0.287839,0.262665,0.654187,0.183051,0.530004,0.218878,0.300816,0.00207686,0.225997,0.487688,0.230404,0.529993,0.329919,0.143177,0.805032,0.57085,0.089704,0.179563,0.540605,0.359774,0.563634,0.848142,0.256767,0.435062,0.226664,0.785953,0.394773,0.292847,0.0949382,0.352655,0.742622,0.823122,0.367684,0.700165,0.258457,0.654742,0.305952,0.0102991,0.159817,0.532764,0.730276,0.319704,0.555004,0.240491,0.436503,0.283145,0.597394,0.452272,0.628973,0.594475,0.416321,0.365565,0.13482,0.610358,0.693748,0.214684,0.474879,0.868553,0.518205,0.424119,0.237985,0.519279,0.000911537,0.745866,0.623664,0.757999,0.438945,0.619652,0.706112,0.40997,0.39196,0.758981,0.355152,0.346355,0.354044,0.115549,0.520214,0.708106,0.144299,0.809543,0.366382,0.271677,0.471879,0.234123,0.0276208,0.621275,0.727464,0.589415,0.564042,0.356483,0.846483,0.256519,0.194538,0.191884,0.509842,0.145092,0.368631,0.321667,0.149733,0.477082,0.368449,0.066291,0.343349,0.450702,0.341084,0.138667,0.459605,0.298707,0.345583,0.299527,0.0888292,0.372757,0.172033,0.181635,0.304651,0.440771,0.0714766,0.445744,0.371991,0.332112,0.326635,0.349721,0.39301,0.396235,0.204251,0.171264,0.388491,0.357781,0.338712,0.231439,0.359148,0.0641227,0.177916,0.232711,0.327419,0.402268,0.479755,0.163801,0.245045,0.373321,0.111784,0.395243,0.130132,0.373481,0.462042,0.213394,0.270174,0.406219,0.298,0.40549,0.30902,0.0755079,0.12783,0.101672,0.0890286,0.465261,0.362561,0.578088,0.285875,0.225945,0.18761,0.20516,0.115576,0.385234,0.291842,0.392097,0.352327,0.232997,0.451856,0.521039,0.0611183,0.294205,0.448388,0.278746,0.387086,0.232479,0.334662,0.336321,0.139427,0.0229328,0.454978,0.366035,0.381922,0.372037,0.263608,0.3488,0.43615,0.218495,0.398705,0.110518,0.316114,0.360691,0.26003,0.35537,0.423126,0.288449,0.244977,0.0225285,0.395958,0.314638,0.322324,0.184473,0.363414,0.524458,0.482957,0.388728,0.157712,0.3633,0.202084,0.104337,0.104656,0.279419,0.149946,0.0797883,0.104584,0.537494,0.454949,0.378002,0.340219,0.412672,0.343186,0.155969,0.186603,0.124175,0.228962,0.12366,0.198264,0.128253,0.14669,0.240899,0.206424,0.0862744,0.129421,0.171188,0.0721407,0.251724,0.36701,0.0342995,0.491191,0.573638,0.263371,0.125459,0.446399,0.360168,0.403229,0.0352084,0.442751,0.323763,0.144478,0.458912,0.246162,0.295506,0.369944,0.358783,0.491474,0.417013,0.186372,0.21822,0.388558,0.397562,0.21727,0.351946,0.345508,0.484083,0.486223,0.113818,0.302171,0.398223,0.178399,0.189006,0.400541,0.372405,0.182559,0.164471,0.533328,0.313891,0.292462,0.132855,0.137165,0.467981,0.191837,0.395568,0.0581034,0.289812,0.384881,0.441686,0.078683,0.592234
}}
}}

Revision as of 11:05, 19 October 2012


Full id: C1293_CD14_CD14CD16_Basophils_Mast_Eosinophils_Neutrophils_Peripheral



Phase1 CAGE Peaks

Hg19::chr10:104575823..104575834,-p@chr10:104575823..104575834
-
Hg19::chr11:72431425..72431435,+p@chr11:72431425..72431435
+
Hg19::chr1:206749144..206749185,+p@chr1:206749144..206749185
+
Hg19::chr1:206749218..206749229,+p@chr1:206749218..206749229
+
Hg19::chr8:17941902..17941958,+p1@ENST00000499554
p1@ENST00000505114
p1@uc003wyp.1
Hg19::chr9:110252263..110252316,+p@chr9:110252263..110252316
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
classical monocyte1.93e-8242
CD14-positive, CD16-negative classical monocyte1.93e-8242
myeloid leukocyte6.52e-7672
defensive cell1.10e-7348
phagocyte1.10e-7348
myeloid lineage restricted progenitor cell7.61e-6266
granulocyte monocyte progenitor cell1.05e-6067
monopoietic cell9.74e-5959
monocyte9.74e-5959
monoblast9.74e-5959
promonocyte9.74e-5959
macrophage dendritic cell progenitor2.25e-5661
leukocyte2.07e-48136
myeloid cell4.16e-45108
common myeloid progenitor4.16e-45108
nongranular leukocyte1.71e-38115
stuff accumulating cell5.47e-3887
hematopoietic lineage restricted progenitor cell9.16e-38120
hematopoietic stem cell7.04e-37168
angioblastic mesenchymal cell7.04e-37168
hematopoietic cell4.79e-34177
hematopoietic oligopotent progenitor cell1.62e-33161
hematopoietic multipotent progenitor cell1.62e-33161
intermediate monocyte2.01e-199
CD14-positive, CD16-positive monocyte2.01e-199
granulocyte1.72e-128
mesenchymal cell7.35e-11354
connective tissue cell2.62e-10361
blood cell1.02e-0811
motile cell2.14e-08386
non-classical monocyte1.32e-073
CD14-low, CD16-positive monocyte1.32e-073
basophil2.81e-073
single nucleate cell6.88e-073
mononuclear cell6.88e-073
Uber Anatomy
Ontology termp-valuen
hematopoietic system3.31e-6198
blood island3.31e-6198
hemolymphoid system5.11e-58108
bone marrow2.86e-5676
bone element4.77e-5182
immune system4.13e-4993
skeletal element3.64e-4590
skeletal system3.87e-39100
lateral plate mesoderm1.75e-26203
musculoskeletal system1.90e-18167
mesoderm5.48e-12315
mesoderm-derived structure5.48e-12315
presumptive mesoderm5.48e-12315
connective tissue4.15e-10371
blood5.21e-0915
haemolymphatic fluid5.21e-0915
organism substance5.21e-0915


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.