FF:10052-101G7: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004809 | ||
| | |accession_numbers=CAGE;DRX008619;DRR009491;DRZ000916;DRZ002301;DRZ012266;DRZ013651 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0007023,UBERON:0000947,UBERON:0001637,UBERON:0000483,UBERON:0000479,UBERON:0000055,UBERON:0004111,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0003914,UBERON:0000025,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0004573,UBERON:0003509,UBERON:0007500,UBERON:0001981,UBERON:0002049,UBERON:0010317,UBERON:0007798,UBERON:0004535,UBERON:0004571,UBERON:0010191,UBERON:0004572,UBERON:0004537,UBERON:0001009 | ||
|ancestors_in_cell_lineage_facet= | |ancestors_in_cell_lineage_facet= | ||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000101,FF:0000001,FF:0000998,FF:0000004,FF:0010052 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr12:52437488..52437507,+!p2@NR4A1!2.22!164.98!NR4A1;;chr1:40105299..40105326,-!p1@HEYL!2.09!123.33!HEYL;;chr2:19558373..19558392,-!p1@OSR1!2.00!263.01!OSR1;;chr20:30433396..30433414,-!p1@FOXS1!1.94!85.28!FOXS1;;chr11:113930425..113930471,+!p1@ZBTB16!1.83!94.44!ZBTB16;;chr7:44143978..44143989,+!p2@AEBP1!1.71!89.06!AEBP1;;chr7:44143925..44143970,+!p1@AEBP1!1.70!1037.29!AEBP1;;chr19:46801639..46801699,+!p1@HIF3A!1.66!44.83!HIF3A;;chr11:34642612..34642646,+!p1@EHF!1.66!44.23!EHF;;chr4:174451370..174451387,-!p1@HAND2!1.66!44.23!HAND2;;chr6:1610293..1610310,+!p1@FOXC1!1.65!70.93!FOXC1;;chr16:86600426..86600441,+!p1@FOXC2!1.63!99.42!FOXC2;;chr12:52445218..52445237,+!p1@NR4A1!1.62!485.17!NR4A1;;chr6:126070769..126070801,+!p1@HEY2!1.62!46.62!HEY2;;chr1:201979703..201979721,+!p2@ELF3!1.62!40.45!ELF3;;chr6:19837592..19837621,+!p1@ID4!1.61!230.73!ID4;;chr20:50179368..50179392,-!p2@NFATC2!1.60!50.21!NFATC2;;chr17:53342311..53342400,+!p1@HLF!1.57!41.64!HLF;;chr5:122424955..122424988,+!p2@PRDM6!1.57!36.46!PRDM6;;chr5:122424918..122424944,+!p1@PRDM6!1.56!35.27!PRDM6;;chr20:62680984..62680999,-!p1@SOX18!1.55!45.23!SOX18;;chr7:44143997..44144008,+!p3@AEBP1!1.54!42.24!AEBP1;;chr18:19749541..19749557,+!p1@GATA6!1.45!83.68!GATA6;;chr5:158526917..158526932,-!p1@EBF1!1.45!65.75!EBF1;;chr21:40032558..40032578,-!p5@ERG!1.43!25.90!ERG;;chr3:21792682..21792720,-!p1@ZNF385D!1.41!24.91!ZNF385D;;chr4:174450089..174450153,-!p2@HAND2!1.41!24.71!HAND2;;chr19:54058073..54058088,+!p1@ZNF331!1.40!24.31!ZNF331;;chr1:201979743..201979762,+!p1@ELF3!1.38!22.91!ELF3;;chr19:45971246..45971265,+!p1@FOSB!1.37!399.89!FOSB;;chr1:61548374..61548415,+!p4@NFIA!1.36!40.65!NFIA;;chr1:170632285..170632309,+!p1@PRRX1!1.36!24.51!PRRX1;;chr3:169381420..169381535,-!p1@MECOM!1.35!24.91!MECOM;;chr6:85474299..85474324,-!p1@TBX18!1.33!35.86!TBX18;;chr1:61548225..61548299,+!p1@NFIA!1.32!254.04!NFIA;;chr19:54041669..54041697,+!p2@ZNF331!1.32!19.73!ZNF331;;chrY:21906594..21906622,-!p1@KDM5D!1.31!19.53!KDM5D;;chr9:132427883..132427951,+!p2@PRRX2!1.31!19.33!PRRX2;;chr11:113930401..113930422,+!p3@ZBTB16!1.31!19.33!ZBTB16;;chr1:2985760..2985774,+!p1@PRDM16!1.30!19.13!PRDM16;;chr3:24536253..24536328,-!p1@THRB!1.29!34.47!THRB;;chr9:102584159..102584174,+!p2@NR4A3!1.29!32.68!NR4A3;;chr17:38256822..38256851,-!p1@NR1D1!1.28!139.27!NR1D1;;chr9:132427972..132428056,+!p1@PRRX2!1.28!23.31!PRRX2;;chr18:19749517..19749531,+!p3@GATA6!1.27!31.08!GATA6;;chr18:77155922..77155939,+!p1@NFATC1!1.26!46.62!NFATC1;;chr8:25902876..25902936,-!p1@EBF2!1.26!17.33!EBF2;;chr14:75745523..75745537,+!p1@FOS!1.24!1930.91!FOS;;chrX:106960180..106960197,-!p2@TSC22D3!1.24!61.57!TSC22D3;;chr1:61548069..61548102,+!p3@NFIA!1.24!39.05!NFIA;;chr11:113930291..113930339,+!p2@ZBTB16!1.23!25.70!ZBTB16;;chr3:181429704..181429722,+!p1@SOX2!1.23!15.94!SOX2;;chr8:106330656..106330684,+!p1@ZFPM2!1.22!40.45!ZFPM2;;chr2:97202480..97202499,+!p1@ARID5A!1.21!150.43!ARID5A;;chr3:126076242..126076257,-!p1@KLF15!1.21!18.93!KLF15;;chr2:157189180..157189290,-!p1@NR4A2!1.20!77.31!NR4A2;;chr2:122042770..122042785,-!p1@TFCP2L1!1.20!14.94!TFCP2L1;;chr8:55370487..55370503,+!p1@SOX17!1.19!14.35!SOX17;;chr16:85932760..85932775,+!p1@IRF8!1.19!14.35!IRF8;;chr1:2985726..2985752,+!p2@PRDM16!1.19!14.35!PRDM16;;chr21:39870339..39870443,-!p1@ERG!1.19!14.35!ERG;;chr3:21792585..21792625,-!p2@ZNF385D!1.16!15.14!ZNF385D;;chr11:47400078..47400106,-!p1@SPI1!1.16!13.35!SPI1;;chr21:40032581..40032605,-!p4@ERG!1.15!13.15!ERG;;chr3:24536485..24536500,-!p3@THRB!1.14!12.95!THRB;;chr3:71294213..71294240,-!p30@FOXP1!1.14!12.75!FOXP1;;chr5:158527104..158527135,-!p4@EBF1!1.14!12.75!EBF1;;chr11:125034640..125034655,+!p1@PKNOX2!1.13!12.35!PKNOX2;;chr5:137804484..137804498,+!p2@EGR1!1.12!49.02!EGR1;;chr12:26277956..26277980,-!p1@BHLHE41!1.12!43.83!BHLHE41;;chr1:212782094..212782109,+!p1@ATF3!1.11!324.97!ATF3;;chr15:42749722..42749739,-!p2@ZFP106!1.11!21.52!ZFP106;;chr18:45935720..45935772,-!p1@ZBTB7C!1.11!11.95!ZBTB7C;;chr5:88178983..88179012,-!p1@MEF2C!1.10!89.86!MEF2C;;chr16:86600870..86600921,+!p2@FOXC2!1.10!11.56!FOXC2;;chr3:169381183..169381205,-!p4@MECOM!1.10!11.56!MECOM;;chr4:174451350..174451363,-!p3@HAND2!1.10!11.56!HAND2;;chr18:19749386..19749404,+!p2@GATA6!1.09!16.34!GATA6;;chr20:51588873..51588953,+!p1@TSHZ2!1.09!15.14!TSHZ2;;chr22:41763452..41763466,+!p2@TEF!1.09!11.36!TEF;;chr8:22550982..22550999,-!p1@EGR3!1.08!31.08!EGR3;;chr7:113726357..113726443,+!p1@FOXP2!1.08!19.13!FOXP2;;chr16:73093174..73093209,-!p3@ZFHX3!1.08!14.94!ZFHX3;;chr12:26277817..26277863,-!p2@BHLHE41!1.08!14.94!BHLHE41;;chr14:75746722..75746777,+!p2@FOS!1.08!14.15!FOS;;chr8:10588010..10588030,-!p1@SOX7!1.08!11.16!SOX7;;chr6:34524093..34524135,-!p1@SPDEF!1.08!10.96!SPDEF;;chr1:10754477..10754517,-!p1@CASZ1!1.07!17.93!CASZ1;;chr21:40032884..40032915,-!p2@ERG!1.07!10.76!ERG;;chr1:61547894..61547968,+!p2@NFIA!1.06!30.88!NFIA;;chr17:38256799..38256815,-!p3@NR1D1!1.06!19.33!NR1D1;;chr2:145277882..145277967,-!p3@ZEB2!1.06!18.33!ZEB2;;chr3:126076264..12607630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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000947;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001637;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001981;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0004573;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0007798 | |||
|ffid_belonging_in_development=UBERON:0002532,UBERON:0006603,UBERON:0004872,UBERON:0006965,UBERON:0010316 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/aorta%252c%2520adult%252c%2520pool1.CNhs11760.10052-101G7.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/aorta%252c%2520adult%252c%2520pool1.CNhs11760.10052-101G7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/aorta%252c%2520adult%252c%2520pool1.CNhs11760.10052-101G7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.tissue.hCAGE/aorta%252c%2520adult%252c%2520pool1.CNhs11760.10052-101G7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.tissue.hCAGE/aorta%252c%2520adult%252c%2520pool1.CNhs11760.10052-101G7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10052-101G7 | |||
|is_a=EFO:0002091;;FF:0010052 | |||
|is_obsolete= | |||
|library_id=CNhs11760 | |||
|library_id_phase_based=2:CNhs11760 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10052 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10052 | |||
|name=aorta, adult, pool1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11760,LSID820,release009,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=101 | |||
|rna_catalog_number=Cat:636546 | |||
|rna_concentration=1 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=9052725A | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=G7 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=101G7 | |||
|rna_weight_ug=50 | |||
|sample_age= | |||
|sample_category=tissues | |||
|sample_cell_catalog=NA | |||
|sample_cell_line= | |||
|sample_cell_lot=NA | |||
|sample_cell_type=CELL MIXTURE - tissue sample | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=Clontech | |||
|sample_description= | |||
|sample_dev_stage=27-45 years old adult | |||
|sample_disease=normal | |||
|sample_donor(cell lot)=4 pool | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;7.49825921138176e-261!GO:0005737;cytoplasm;4.59462008736381e-166!GO:0043226;organelle;9.06085725925409e-109!GO:0043229;intracellular organelle;2.22903655792662e-108!GO:0005515;protein binding;4.28856825061637e-104!GO:0044444;cytoplasmic part;1.23630995019007e-99!GO:0043227;membrane-bound organelle;2.25196646260189e-96!GO:0043231;intracellular membrane-bound organelle;2.31617172906384e-96!GO:0044422;organelle part;1.77665551522928e-63!GO:0044446;intracellular organelle part;3.42595269287711e-62!GO:0032991;macromolecular complex;3.52048506202525e-51!GO:0016043;cellular component organization and biogenesis;1.25987328656337e-46!GO:0030529;ribonucleoprotein complex;5.21150915346001e-40!GO:0019538;protein metabolic process;2.28546623435797e-37!GO:0044238;primary metabolic process;1.27631066722609e-36!GO:0043170;macromolecule metabolic process;5.119420105245e-36!GO:0044237;cellular metabolic process;3.88140000258566e-35!GO:0003723;RNA binding;6.52120186171554e-34!GO:0031090;organelle membrane;1.07900740133722e-33!GO:0033036;macromolecule localization;2.59475183348156e-33!GO:0015031;protein transport;3.94354817606416e-33!GO:0045184;establishment of protein localization;7.1645138517813e-32!GO:0044260;cellular macromolecule metabolic process;1.24231641826293e-31!GO:0008104;protein localization;1.35541260718309e-31!GO:0005739;mitochondrion;2.66976503192575e-31!GO:0043233;organelle lumen;3.65145962255827e-31!GO:0031974;membrane-enclosed lumen;3.65145962255827e-31!GO:0044267;cellular protein metabolic process;3.83970449122947e-30!GO:0044428;nuclear part;8.8081521788419e-28!GO:0043234;protein complex;2.18633575470477e-27!GO:0046907;intracellular transport;7.790716713639e-27!GO:0005829;cytosol;1.58585978141872e-26!GO:0005634;nucleus;4.79727878549034e-26!GO:0005840;ribosome;1.27862153554983e-25!GO:0031967;organelle envelope;3.47813789745125e-24!GO:0006412;translation;4.46359553205678e-24!GO:0031975;envelope;5.24328157099868e-24!GO:0006886;intracellular protein transport;1.07271454224013e-23!GO:0044429;mitochondrial part;2.7864225895201e-23!GO:0003735;structural constituent of ribosome;1.49069831466989e-22!GO:0065003;macromolecular complex assembly;1.19531550863797e-21!GO:0022607;cellular component assembly;2.06007818247401e-21!GO:0016071;mRNA metabolic process;3.17684601847939e-21!GO:0033279;ribosomal subunit;4.09015334131845e-20!GO:0008134;transcription factor binding;1.99751856864603e-19!GO:0009059;macromolecule biosynthetic process;2.55759899361513e-19!GO:0008380;RNA splicing;3.90663253683241e-19!GO:0051641;cellular localization;1.6679265740938e-18!GO:0048523;negative regulation of cellular process;2.85589629711076e-18!GO:0051649;establishment of cellular localization;3.87019495285175e-18!GO:0005783;endoplasmic reticulum;9.61302541203175e-18!GO:0048770;pigment granule;1.13040118660042e-17!GO:0042470;melanosome;1.13040118660042e-17!GO:0016192;vesicle-mediated transport;2.53056678110285e-17!GO:0005740;mitochondrial envelope;2.53056678110285e-17!GO:0009058;biosynthetic process;2.55576137040906e-17!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.907238190328e-17!GO:0006396;RNA processing;4.51800548244751e-17!GO:0048519;negative regulation of biological process;4.89122657018034e-17!GO:0006397;mRNA processing;5.11180305654672e-17!GO:0031966;mitochondrial membrane;6.43902413329895e-17!GO:0044249;cellular biosynthetic process;1.12526488125958e-16!GO:0005794;Golgi apparatus;1.2602408511607e-16!GO:0031981;nuclear lumen;1.64517982067102e-16!GO:0019866;organelle inner membrane;1.23289115421572e-15!GO:0006996;organelle organization and biogenesis;3.10496743262475e-15!GO:0043283;biopolymer metabolic process;8.50581498607835e-15!GO:0006119;oxidative phosphorylation;9.11310481017448e-15!GO:0043228;non-membrane-bound organelle;1.50624421746169e-14!GO:0043232;intracellular non-membrane-bound organelle;1.50624421746169e-14!GO:0005743;mitochondrial inner membrane;1.55434314822831e-14!GO:0012505;endomembrane system;2.55289061367535e-14!GO:0044445;cytosolic part;3.1319968818231e-14!GO:0010467;gene expression;6.89041233972463e-14!GO:0008092;cytoskeletal protein binding;7.87260654632504e-14!GO:0005681;spliceosome;1.45625271013044e-13!GO:0012501;programmed cell death;2.46274232482235e-13!GO:0030036;actin cytoskeleton organization and biogenesis;4.16091458334257e-13!GO:0008219;cell death;4.62997194955668e-13!GO:0016265;death;4.62997194955668e-13!GO:0006915;apoptosis;6.57301854778559e-13!GO:0000166;nucleotide binding;1.70908657184907e-12!GO:0048193;Golgi vesicle transport;1.70908657184907e-12!GO:0005746;mitochondrial respiratory chain;4.40793366237974e-12!GO:0006605;protein targeting;5.41382321525977e-12!GO:0006457;protein folding;5.78811895677094e-12!GO:0051603;proteolysis involved in cellular protein catabolic process;1.13744320678422e-11!GO:0030029;actin filament-based process;1.16961381665969e-11!GO:0003712;transcription cofactor activity;1.27915027304566e-11!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.41809852945727e-11!GO:0019941;modification-dependent protein catabolic process;2.27840803703221e-11!GO:0043632;modification-dependent macromolecule catabolic process;2.27840803703221e-11!GO:0005654;nucleoplasm;2.47653944090171e-11!GO:0006511;ubiquitin-dependent protein catabolic process;2.52263211642117e-11!GO:0044257;cellular protein catabolic process;2.52263211642117e-11!GO:0044455;mitochondrial membrane part;2.84960739398255e-11!GO:0015935;small ribosomal subunit;3.64380981003928e-11!GO:0050136;NADH dehydrogenase (quinone) activity;3.6583283650245e-11!GO:0003954;NADH dehydrogenase activity;3.6583283650245e-11!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.6583283650245e-11!GO:0006461;protein complex assembly;3.70210263911546e-11!GO:0043412;biopolymer modification;4.23359379482558e-11!GO:0044265;cellular macromolecule catabolic process;4.68021602851745e-11!GO:0006464;protein modification process;9.36292944477777e-11!GO:0044432;endoplasmic reticulum part;9.55658529516261e-11!GO:0022618;protein-RNA complex assembly;1.03343363812712e-10!GO:0006512;ubiquitin cycle;1.07299699361629e-10!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.08970333383852e-10!GO:0006366;transcription from RNA polymerase II promoter;1.22789583032579e-10!GO:0043687;post-translational protein modification;1.54112800856651e-10!GO:0050789;regulation of biological process;1.54112800856651e-10!GO:0050794;regulation of cellular process;3.18858020651273e-10!GO:0031982;vesicle;3.50728979214012e-10!GO:0016462;pyrophosphatase activity;3.6386940103796e-10!GO:0031988;membrane-bound vesicle;3.6386940103796e-10!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.12729771425225e-10!GO:0044451;nucleoplasm part;4.8727931279197e-10!GO:0016564;transcription repressor activity;4.89164623281803e-10!GO:0016049;cell growth;5.22050904292933e-10!GO:0043285;biopolymer catabolic process;5.25433784907959e-10!GO:0015934;large ribosomal subunit;5.7365644017533e-10!GO:0016817;hydrolase activity, acting on acid anhydrides;5.77072842862416e-10!GO:0017111;nucleoside-triphosphatase activity;6.25665716480147e-10!GO:0016023;cytoplasmic membrane-bound vesicle;7.05483630630711e-10!GO:0008361;regulation of cell size;7.35416199063351e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;7.82639024983504e-10!GO:0016874;ligase activity;7.94805876162462e-10!GO:0031410;cytoplasmic vesicle;8.31793175818051e-10!GO:0030163;protein catabolic process;9.77334588572515e-10!GO:0008135;translation factor activity, nucleic acid binding;1.02317396508442e-09!GO:0006913;nucleocytoplasmic transport;1.19452015088533e-09!GO:0030964;NADH dehydrogenase complex (quinone);1.96304884998582e-09!GO:0045271;respiratory chain complex I;1.96304884998582e-09!GO:0005747;mitochondrial respiratory chain complex I;1.96304884998582e-09!GO:0003779;actin binding;2.61994871653563e-09!GO:0051169;nuclear transport;2.79720087263135e-09!GO:0006793;phosphorus metabolic process;3.17875055269845e-09!GO:0006796;phosphate metabolic process;3.17875055269845e-09!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.57231633381336e-09!GO:0042775;organelle ATP synthesis coupled electron transport;3.97194375959061e-09!GO:0042773;ATP synthesis coupled electron transport;3.97194375959061e-09!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.75567619420048e-09!GO:0000502;proteasome complex (sensu Eukaryota);5.09491986335855e-09!GO:0008565;protein transporter activity;5.48433702639451e-09!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.87005202993691e-09!GO:0005793;ER-Golgi intermediate compartment;8.61739846736364e-09!GO:0007264;small GTPase mediated signal transduction;1.06598236700754e-08!GO:0017076;purine nucleotide binding;1.09330535183254e-08!GO:0032553;ribonucleotide binding;1.10879167065231e-08!GO:0032555;purine ribonucleotide binding;1.10879167065231e-08!GO:0031252;leading edge;1.25358964787978e-08!GO:0051082;unfolded protein binding;1.60867951789641e-08!GO:0009057;macromolecule catabolic process;1.88326256567723e-08!GO:0001558;regulation of cell growth;2.37661272242562e-08!GO:0003714;transcription corepressor activity;2.8864872203013e-08!GO:0031980;mitochondrial lumen;3.8690333823452e-08!GO:0005759;mitochondrial matrix;3.8690333823452e-08!GO:0005768;endosome;4.43158863830483e-08!GO:0017038;protein import;5.23493602437267e-08!GO:0019899;enzyme binding;7.26494181380091e-08!GO:0003743;translation initiation factor activity;9.52309424210153e-08!GO:0005635;nuclear envelope;1.39592105606099e-07!GO:0031324;negative regulation of cellular metabolic process;1.44102838388171e-07!GO:0007243;protein kinase cascade;1.9407543247106e-07!GO:0044248;cellular catabolic process;1.96643656268443e-07!GO:0008639;small protein conjugating enzyme activity;1.97963229136355e-07!GO:0005773;vacuole;2.12383667925041e-07!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.33244740819484e-07!GO:0000398;nuclear mRNA splicing, via spliceosome;2.35076142455151e-07!GO:0000375;RNA splicing, via transesterification reactions;2.35076142455151e-07!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;2.35076142455151e-07!GO:0009892;negative regulation of metabolic process;2.54875106581948e-07!GO:0004842;ubiquitin-protein ligase activity;2.66858596342937e-07!GO:0065007;biological regulation;2.79364923468266e-07!GO:0043069;negative regulation of programmed cell death;2.84182755459089e-07!GO:0007010;cytoskeleton organization and biogenesis;3.3543998993847e-07!GO:0005788;endoplasmic reticulum lumen;3.39471165835935e-07!GO:0051789;response to protein stimulus;3.76784403558942e-07!GO:0006986;response to unfolded protein;3.76784403558942e-07!GO:0031965;nuclear membrane;4.05782783982118e-07!GO:0006446;regulation of translational initiation;4.23826265627851e-07!GO:0042981;regulation of apoptosis;4.27122502820103e-07!GO:0016310;phosphorylation;4.30081284100408e-07!GO:0043067;regulation of programmed cell death;4.62397091824213e-07!GO:0016481;negative regulation of transcription;5.29438846397182e-07!GO:0043066;negative regulation of apoptosis;5.46783765614156e-07!GO:0000323;lytic vacuole;5.61321116326686e-07!GO:0005764;lysosome;5.61321116326686e-07!GO:0006606;protein import into nucleus;6.28287786792675e-07!GO:0040008;regulation of growth;6.34843236056012e-07!GO:0003924;GTPase activity;6.62826632442947e-07!GO:0016604;nuclear body;6.92293717052034e-07!GO:0009055;electron carrier activity;7.23525124903143e-07!GO:0006413;translational initiation;7.29350699036835e-07!GO:0051246;regulation of protein metabolic process;7.77721165508631e-07!GO:0009966;regulation of signal transduction;7.94754097666692e-07!GO:0051170;nuclear import;9.00983462309083e-07!GO:0016044;membrane organization and biogenesis;9.51378440098166e-07!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;9.67652490230954e-07!GO:0019787;small conjugating protein ligase activity;1.00585318625105e-06!GO:0007242;intracellular signaling cascade;1.49248012962191e-06!GO:0006916;anti-apoptosis;1.69444832135848e-06!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.83256205867335e-06!GO:0005789;endoplasmic reticulum membrane;2.03102349489009e-06!GO:0030120;vesicle coat;2.33152756155682e-06!GO:0030662;coated vesicle membrane;2.33152756155682e-06!GO:0048475;coated membrane;2.36718561462865e-06!GO:0030117;membrane coat;2.36718561462865e-06!GO:0045786;negative regulation of progression through cell cycle;2.58489700813974e-06!GO:0044431;Golgi apparatus part;2.84949574453075e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;3.25388835200609e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.33461945753266e-06!GO:0016607;nuclear speck;3.40226437575252e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.65908957032482e-06!GO:0048522;positive regulation of cellular process;4.42623331262776e-06!GO:0005525;GTP binding;4.87296698061897e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;4.93061419860961e-06!GO:0031589;cell-substrate adhesion;5.39046445139198e-06!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.39046445139198e-06!GO:0019829;cation-transporting ATPase activity;6.81283686067194e-06!GO:0016879;ligase activity, forming carbon-nitrogen bonds;6.91750491067434e-06!GO:0051186;cofactor metabolic process;6.971410816452e-06!GO:0005761;mitochondrial ribosome;8.78611624266284e-06!GO:0000313;organellar ribosome;8.78611624266284e-06!GO:0009060;aerobic respiration;1.01842110130525e-05!GO:0016881;acid-amino acid ligase activity;1.17885467981404e-05!GO:0005524;ATP binding;1.58599651398425e-05!GO:0032559;adenyl ribonucleotide binding;1.70563360407879e-05!GO:0016563;transcription activator activity;1.80592256692064e-05!GO:0030554;adenyl nucleotide binding;1.86256076565584e-05!GO:0006888;ER to Golgi vesicle-mediated transport;1.91486232060022e-05!GO:0015078;hydrogen ion transmembrane transporter activity;2.11321487399294e-05!GO:0007160;cell-matrix adhesion;2.31876641922851e-05!GO:0005730;nucleolus;2.32767127777484e-05!GO:0016469;proton-transporting two-sector ATPase complex;2.72825109756595e-05!GO:0005770;late endosome;3.02686962637382e-05!GO:0032561;guanyl ribonucleotide binding;3.10725311884886e-05!GO:0019001;guanyl nucleotide binding;3.10725311884886e-05!GO:0045333;cellular respiration;3.28191438841235e-05!GO:0006897;endocytosis;3.47158377277443e-05!GO:0010324;membrane invagination;3.47158377277443e-05!GO:0015986;ATP synthesis coupled proton transport;3.47808781573847e-05!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.47808781573847e-05!GO:0015629;actin cytoskeleton;3.50305939485123e-05!GO:0048518;positive regulation of biological process;3.57930221571371e-05!GO:0030133;transport vesicle;3.68535917279954e-05!GO:0003713;transcription coactivator activity;3.88368783693663e-05!GO:0000902;cell morphogenesis;4.23107789914101e-05!GO:0032989;cellular structure morphogenesis;4.23107789914101e-05!GO:0044420;extracellular matrix part;4.47811980036168e-05!GO:0007265;Ras protein signal transduction;4.68919096929784e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.68919096929784e-05!GO:0008286;insulin receptor signaling pathway;5.70406825683075e-05!GO:0005798;Golgi-associated vesicle;6.2888873702669e-05!GO:0048471;perinuclear region of cytoplasm;7.14923993079585e-05!GO:0000139;Golgi membrane;7.26608136872454e-05!GO:0045892;negative regulation of transcription, DNA-dependent;9.54796975234137e-05!GO:0005791;rough endoplasmic reticulum;9.55868025546228e-05!GO:0015980;energy derivation by oxidation of organic compounds;9.57992651341915e-05!GO:0006163;purine nucleotide metabolic process;9.93961474942742e-05!GO:0009056;catabolic process;0.000109029462527725!GO:0044453;nuclear membrane part;0.000112339702666407!GO:0009199;ribonucleoside triphosphate metabolic process;0.000117047170033873!GO:0001726;ruffle;0.000123489181900579!GO:0009141;nucleoside triphosphate metabolic process;0.000138303623708075!GO:0009150;purine ribonucleotide metabolic process;0.00014191458979171!GO:0006732;coenzyme metabolic process;0.000143064802004354!GO:0006950;response to stress;0.000144500420281767!GO:0006099;tricarboxylic acid cycle;0.00014550992786323!GO:0046356;acetyl-CoA catabolic process;0.00014550992786323!GO:0009142;nucleoside triphosphate biosynthetic process;0.000161436189058381!GO:0009201;ribonucleoside triphosphate biosynthetic process;0.000161436189058381!GO:0045259;proton-transporting ATP synthase complex;0.000164602312070379!GO:0009205;purine ribonucleoside triphosphate metabolic process;0.000164602312070379!GO:0009144;purine nucleoside triphosphate metabolic process;0.000164602312070379!GO:0044440;endosomal part;0.000178395335393887!GO:0010008;endosome membrane;0.000178395335393887!GO:0016070;RNA metabolic process;0.000185262529883189!GO:0051128;regulation of cellular component organization and biogenesis;0.000200290251197069!GO:0005083;small GTPase regulator activity;0.00020814858266315!GO:0045792;negative regulation of cell size;0.000211430269214694!GO:0009109;coenzyme catabolic process;0.00021280344027493!GO:0030308;negative regulation of cell growth;0.000220487877788262!GO:0009259;ribonucleotide metabolic process;0.000221896580071098!GO:0051187;cofactor catabolic process;0.000225786026243508!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;0.000227415809468941!GO:0009145;purine nucleoside triphosphate biosynthetic process;0.000227415809468941!GO:0000151;ubiquitin ligase complex;0.000254295218469757!GO:0045893;positive regulation of transcription, DNA-dependent;0.000255698957554345!GO:0006613;cotranslational protein targeting to membrane;0.000263037336593503!GO:0016887;ATPase activity;0.000271604418764267!GO:0043566;structure-specific DNA binding;0.000275931222982409!GO:0030027;lamellipodium;0.000276613303265973!GO:0030695;GTPase regulator activity;0.000282020101801465!GO:0006164;purine nucleotide biosynthetic process;0.000289125290250381!GO:0030532;small nuclear ribonucleoprotein complex;0.000291694769526225!GO:0048468;cell development;0.000346171974349305!GO:0005581;collagen;0.000346171974349305!GO:0005769;early endosome;0.000349823320031678!GO:0000245;spliceosome assembly;0.00038331632963582!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000387713951013188!GO:0009152;purine ribonucleotide biosynthetic process;0.000409026120323176!GO:0001666;response to hypoxia;0.000444046810667436!GO:0005912;adherens junction;0.000489373709587335!GO:0006325;establishment and/or maintenance of chromatin architecture;0.000501406731532876!GO:0005643;nuclear pore;0.00050489531400988!GO:0016197;endosome transport;0.000515867965804919!GO:0051427;hormone receptor binding;0.000515867965804919!GO:0005839;proteasome core complex (sensu Eukaryota);0.00053502600679466!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000539513900077033!GO:0005905;coated pit;0.000542179933806267!GO:0046034;ATP metabolic process;0.000565604316031644!GO:0042802;identical protein binding;0.000567045243609065!GO:0008154;actin polymerization and/or depolymerization;0.000592700202737533!GO:0006091;generation of precursor metabolites and energy;0.000608618469580337!GO:0005741;mitochondrial outer membrane;0.000626868842552929!GO:0006084;acetyl-CoA metabolic process;0.000660900991970723!GO:0045941;positive regulation of transcription;0.000661347805124844!GO:0007167;enzyme linked receptor protein signaling pathway;0.000680268612466354!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000690436136826116!GO:0032446;protein modification by small protein conjugation;0.000710854576558375!GO:0006754;ATP biosynthetic process;0.000710865669141734!GO:0006753;nucleoside phosphate metabolic process;0.000710865669141734!GO:0016567;protein ubiquitination;0.00073566726887262!GO:0030867;rough endoplasmic reticulum membrane;0.000756896554322114!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000766046380468722!GO:0003697;single-stranded DNA binding;0.000827103234918992!GO:0005520;insulin-like growth factor binding;0.00085405911097625!GO:0051674;localization of cell;0.000924965715315137!GO:0006928;cell motility;0.000924965715315137!GO:0009260;ribonucleotide biosynthetic process;0.000936083449310353!GO:0035257;nuclear hormone receptor binding;0.000938770267439646!GO:0001568;blood vessel development;0.000946630971380293!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000958767289312738!GO:0001944;vasculature development;0.0010457258975895!GO:0019843;rRNA binding;0.00105347336565634!GO:0045045;secretory pathway;0.00109071913763174!GO:0019838;growth factor binding;0.00113684625726893!GO:0044262;cellular carbohydrate metabolic process;0.00115127755707783!GO:0008283;cell proliferation;0.00121983405520034!GO:0007266;Rho protein signal transduction;0.00122426201784457!GO:0033673;negative regulation of kinase activity;0.00123739338044946!GO:0006469;negative regulation of protein kinase activity;0.00123739338044946!GO:0019867;outer membrane;0.00123750156043275!GO:0005885;Arp2/3 protein complex;0.00134825407182979!GO:0006259;DNA metabolic process;0.0013533006483971!GO:0001725;stress fiber;0.00143589678916358!GO:0032432;actin filament bundle;0.00143589678916358!GO:0008047;enzyme activator activity;0.00153167210878967!GO:0045926;negative regulation of growth;0.00153734887610278!GO:0006323;DNA packaging;0.00159534082296741!GO:0031968;organelle outer membrane;0.00166422249701118!GO:0006979;response to oxidative stress;0.00172216447592105!GO:0006892;post-Golgi vesicle-mediated transport;0.00182153231638361!GO:0007179;transforming growth factor beta receptor signaling pathway;0.00185734028740753!GO:0042623;ATPase activity, coupled;0.00188649786345961!GO:0030041;actin filament polymerization;0.00188686393131386!GO:0003676;nucleic acid binding;0.00189091043729647!GO:0033116;ER-Golgi intermediate compartment membrane;0.00199201203396608!GO:0004298;threonine endopeptidase activity;0.00200079695556518!GO:0005096;GTPase activator activity;0.00202479329099032!GO:0065002;intracellular protein transport across a membrane;0.00215065484932259!GO:0051726;regulation of cell cycle;0.00221387232510194!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00229086022434005!GO:0009967;positive regulation of signal transduction;0.00235952869598379!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.0023623803907011!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00243223687943512!GO:0000074;regulation of progression through cell cycle;0.00259495844349459!GO:0005856;cytoskeleton;0.00263919267963313!GO:0005048;signal sequence binding;0.00278962747165661!GO:0051270;regulation of cell motility;0.00278962747165661!GO:0032940;secretion by cell;0.00315023628407884!GO:0051348;negative regulation of transferase activity;0.00315405453567445!GO:0003724;RNA helicase activity;0.00322585861251283!GO:0005100;Rho GTPase activator activity;0.00328349184499823!GO:0050657;nucleic acid transport;0.00347958607565511!GO:0051236;establishment of RNA localization;0.00347958607565511!GO:0050658;RNA transport;0.00347958607565511!GO:0007229;integrin-mediated signaling pathway;0.00349878091593446!GO:0043623;cellular protein complex assembly;0.003564379369714!GO:0046930;pore complex;0.00360624053955898!GO:0016568;chromatin modification;0.00363624221401096!GO:0006403;RNA localization;0.00375217768150418!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00377174783333818!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00377174783333818!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00377174783333818!GO:0016791;phosphoric monoester hydrolase activity;0.00388985701029891!GO:0006607;NLS-bearing substrate import into nucleus;0.00418719738523564!GO:0017166;vinculin binding;0.00420620625123086!GO:0030132;clathrin coat of coated pit;0.00427346847790502!GO:0016311;dephosphorylation;0.00431349209686918!GO:0016491;oxidoreductase activity;0.00433583787031564!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00437641215441235!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00471742777329085!GO:0022890;inorganic cation transmembrane transporter activity;0.00477371819812683!GO:0051920;peroxiredoxin activity;0.00479893882119556!GO:0065009;regulation of a molecular function;0.0051539839732361!GO:0008305;integrin complex;0.00525077686650208!GO:0004721;phosphoprotein phosphatase activity;0.00542857926334777!GO:0008654;phospholipid biosynthetic process;0.00550534394531809!GO:0009893;positive regulation of metabolic process;0.00552206232436527!GO:0008026;ATP-dependent helicase activity;0.00561606981254229!GO:0030198;extracellular matrix organization and biogenesis;0.00604103063072131!GO:0001516;prostaglandin biosynthetic process;0.00609307111258012!GO:0046457;prostanoid biosynthetic process;0.00609307111258012!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00615858474172794!GO:0006612;protein targeting to membrane;0.00622563027506565!GO:0030134;ER to Golgi transport vesicle;0.00637259705198999!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.00643045629757135!GO:0030127;COPII vesicle coat;0.00649701042782039!GO:0012507;ER to Golgi transport vesicle membrane;0.00649701042782039!GO:0030118;clathrin coat;0.00661448372913072!GO:0030663;COPI coated vesicle membrane;0.00677064654725668!GO:0030126;COPI vesicle coat;0.00677064654725668!GO:0043488;regulation of mRNA stability;0.00677718738695586!GO:0043487;regulation of RNA stability;0.00677718738695586!GO:0007050;cell cycle arrest;0.00677890370910954!GO:0030658;transport vesicle membrane;0.00733241349815315!GO:0006402;mRNA catabolic process;0.00745821708498716!GO:0006891;intra-Golgi vesicle-mediated transport;0.0078205643504599!GO:0007517;muscle development;0.0078914172031615!GO:0016859;cis-trans isomerase activity;0.00803876683166723!GO:0008287;protein serine/threonine phosphatase complex;0.00832667609196832!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00848747161976817!GO:0005667;transcription factor complex;0.00877924154833134!GO:0006752;group transfer coenzyme metabolic process;0.00879708348038842!GO:0008250;oligosaccharyl transferase complex;0.00893953932922313!GO:0007178;transmembrane receptor protein serine/threonine kinase signaling pathway;0.00894526801467775!GO:0030659;cytoplasmic vesicle membrane;0.00897040916318345!GO:0051252;regulation of RNA metabolic process;0.00915852008355969!GO:0048514;blood vessel morphogenesis;0.00934380632072914!GO:0016301;kinase activity;0.0093491427826578!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00942951713134709!GO:0040011;locomotion;0.00949162581481048!GO:0030199;collagen fibril organization;0.00961582195880969!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;0.00961582195880969!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.00979781096868846!GO:0033043;regulation of organelle organization and biogenesis;0.00979781096868846!GO:0040012;regulation of locomotion;0.0101575441689898!GO:0031072;heat shock protein binding;0.0101640274337583!GO:0035258;steroid hormone receptor binding;0.0103865692195565!GO:0048659;smooth muscle cell proliferation;0.0103865692195565!GO:0009117;nucleotide metabolic process;0.0105331191709889!GO:0043205;fibril;0.0105840700467058!GO:0030518;steroid hormone receptor signaling pathway;0.0107649529872669!GO:0019902;phosphatase binding;0.010803929358789!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.01083154975432!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.0108769850599864!GO:0004812;aminoacyl-tRNA ligase activity;0.0108769850599864!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.0108769850599864!GO:0012506;vesicle membrane;0.010917211245461!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0114869309747359!GO:0050811;GABA receptor binding;0.0117632838913413!GO:0008139;nuclear localization sequence binding;0.0118718478258494!GO:0060090;molecular adaptor activity;0.0119161159740156!GO:0006470;protein amino acid dephosphorylation;0.0120751506328496!GO:0007015;actin filament organization;0.0124071522509475!GO:0015631;tubulin binding;0.0127850247800801!GO:0030137;COPI-coated vesicle;0.0127850247800801!GO:0004386;helicase activity;0.0127850247800801!GO:0051188;cofactor biosynthetic process;0.0129917419439057!GO:0048660;regulation of smooth muscle cell proliferation;0.0130581501372434!GO:0051259;protein oligomerization;0.0136091081380311!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0136990124212375!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0141160358684466!GO:0015399;primary active transmembrane transporter activity;0.0141160358684466!GO:0003702;RNA polymerase II transcription factor activity;0.0143737798372435!GO:0019904;protein domain specific binding;0.0143737798372435!GO:0044433;cytoplasmic vesicle part;0.0147079691819199!GO:0007005;mitochondrion organization and biogenesis;0.0148303504220326!GO:0031902;late endosome membrane;0.014973355757098!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0149967398767286!GO:0030100;regulation of endocytosis;0.015338568019676!GO:0004576;oligosaccharyl transferase activity;0.0154732046085855!GO:0031032;actomyosin structure organization and biogenesis;0.0158050752109895!GO:0007169;transmembrane receptor protein tyrosine kinase signaling pathway;0.0158059917026522!GO:0003729;mRNA binding;0.0158059917026522!GO:0005762;mitochondrial large ribosomal subunit;0.0158059917026522!GO:0000315;organellar large ribosomal subunit;0.0158059917026522!GO:0006509;membrane protein ectodomain proteolysis;0.0158059917026522!GO:0033619;membrane protein proteolysis;0.0158059917026522!GO:0008186;RNA-dependent ATPase activity;0.0164896741505972!GO:0005099;Ras GTPase activator activity;0.0168238580178758!GO:0005774;vacuolar membrane;0.0168424532499018!GO:0001525;angiogenesis;0.0169319352880069!GO:0051049;regulation of transport;0.0171019703025759!GO:0003746;translation elongation factor activity;0.0172775461860639!GO:0004722;protein serine/threonine phosphatase activity;0.0178215794309937!GO:0043407;negative regulation of MAP kinase activity;0.0179039296259704!GO:0030660;Golgi-associated vesicle membrane;0.0179039296259704!GO:0051028;mRNA transport;0.0181346769137642!GO:0043034;costamere;0.0181549685119623!GO:0007049;cell cycle;0.0182767474755842!GO:0043021;ribonucleoprotein binding;0.0183701978531027!GO:0005518;collagen binding;0.0188805258952934!GO:0043038;amino acid activation;0.0188805258952934!GO:0006418;tRNA aminoacylation for protein translation;0.0188805258952934!GO:0043039;tRNA aminoacylation;0.0188805258952934!GO:0015630;microtubule cytoskeleton;0.0193096210170909!GO:0048500;signal recognition particle;0.0197587701622491!GO:0051087;chaperone binding;0.0200042947419432!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0205437865820933!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0208794631055924!GO:0030031;cell projection biogenesis;0.0209349003464391!GO:0005852;eukaryotic translation initiation factor 3 complex;0.0211828434005991!GO:0006414;translational elongation;0.0212292583736835!GO:0005869;dynactin complex;0.0214354103175425!GO:0045637;regulation of myeloid cell differentiation;0.0218769140033632!GO:0001527;microfibril;0.022494248638741!GO:0004674;protein serine/threonine kinase activity;0.0229776658498912!GO:0051056;regulation of small GTPase mediated signal transduction;0.023104403570265!GO:0006693;prostaglandin metabolic process;0.023130366321392!GO:0006692;prostanoid metabolic process;0.023130366321392!GO:0005924;cell-substrate adherens junction;0.0241066436989754!GO:0045944;positive regulation of transcription from RNA polymerase II promoter;0.0241144865402681!GO:0048487;beta-tubulin binding;0.0248223580654344!GO:0051287;NAD binding;0.0252685535400601!GO:0003690;double-stranded DNA binding;0.0253384142608947!GO:0030334;regulation of cell migration;0.0253903202958004!GO:0051235;maintenance of localization;0.0258637375955063!GO:0046983;protein dimerization activity;0.0264331474785543!GO:0006333;chromatin assembly or disassembly;0.0268333559816768!GO:0051168;nuclear export;0.0268661090909794!GO:0016584;nucleosome positioning;0.027377499981482!GO:0005765;lysosomal membrane;0.0278442756530841!GO:0000059;protein import into nucleus, docking;0.0279120494544621!GO:0005925;focal adhesion;0.0280089938180223!GO:0035035;histone acetyltransferase binding;0.0281719827555138!GO:0006650;glycerophospholipid metabolic process;0.0281719827555138!GO:0045454;cell redox homeostasis;0.0286505123997419!GO:0030032;lamellipodium biogenesis;0.029798500556474!GO:0031901;early endosome membrane;0.029866571174153!GO:0008354;germ cell migration;0.0303309169656876!GO:0018106;peptidyl-histidine phosphorylation;0.0303309169656876!GO:0005201;extracellular matrix structural constituent;0.0308601902746085!GO:0030055;cell-matrix junction;0.0311231594336631!GO:0043284;biopolymer biosynthetic process;0.0313270367794541!GO:0022415;viral reproductive process;0.0313498140724058!GO:0005583;fibrillar collagen;0.0320104522524548!GO:0033002;muscle cell proliferation;0.0328952394220608!GO:0030522;intracellular receptor-mediated signaling pathway;0.0330372012098357!GO:0043492;ATPase activity, coupled to movement of substances;0.0332500305072093!GO:0009108;coenzyme biosynthetic process;0.0334634943606325!GO:0008147;structural constituent of bone;0.0334634943606325!GO:0030119;AP-type membrane coat adaptor complex;0.0339820271191494!GO:0030521;androgen receptor signaling pathway;0.0341923534268338!GO:0051260;protein homooligomerization;0.0343932631719305!GO:0006401;RNA catabolic process;0.0350489262296611!GO:0030836;positive regulation of actin filament depolymerization;0.0351725327677333!GO:0005070;SH3/SH2 adaptor activity;0.0363838124153522!GO:0017091;AU-rich element binding;0.0363838124153522!GO:0050779;RNA destabilization;0.0363838124153522!GO:0000289;poly(A) tail shortening;0.0363838124153522!GO:0030832;regulation of actin filament length;0.0373108252607111!GO:0051101;regulation of DNA binding;0.0373108252607111!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0374968054765884!GO:0004364;glutathione transferase activity;0.0378950222813342!GO:0031529;ruffle organization and biogenesis;0.0382225523274832!GO:0004004;ATP-dependent RNA helicase activity;0.038295942312976!GO:0032956;regulation of actin cytoskeleton organization and biogenesis;0.0395535308080431!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0396985770397805!GO:0045047;protein targeting to ER;0.0396985770397805!GO:0032535;regulation of cellular component size;0.0399231637294916!GO:0046578;regulation of Ras protein signal transduction;0.0401682165311216!GO:0018196;peptidyl-asparagine modification;0.0404018887673082!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0404018887673082!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0406788609370625!GO:0042254;ribosome biogenesis and assembly;0.0410474152688939!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.041498588904411!GO:0005938;cell cortex;0.0415518492385409!GO:0031325;positive regulation of cellular metabolic process;0.0421214018263013!GO:0043681;protein import into mitochondrion;0.0434883438337346!GO:0030241;muscle thick filament assembly;0.0434883438337346!GO:0031034;myosin filament assembly;0.0434883438337346!GO:0031033;myosin filament assembly or disassembly;0.0434883438337346!GO:0048739;cardiac muscle fiber development;0.0434883438337346!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0436979131318017!GO:0015002;heme-copper terminal oxidase activity;0.0436979131318017!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0436979131318017!GO:0004129;cytochrome-c oxidase activity;0.0436979131318017!GO:0007040;lysosome organization and biogenesis;0.0439601182285282!GO:0051098;regulation of binding;0.0440283407408036!GO:0000314;organellar small ribosomal subunit;0.0456120042477636!GO:0005763;mitochondrial small ribosomal subunit;0.0456120042477636!GO:0030176;integral to endoplasmic reticulum membrane;0.0459230039570994!GO:0051338;regulation of transferase activity;0.0463283862726298!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0472618575585632!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0477200128733958!GO:0006818;hydrogen transport;0.0480611987037268!GO:0019208;phosphatase regulator activity;0.0482351431216401!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0484048459689884!GO:0019903;protein phosphatase binding;0.0497166816152672!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0498803059539583 | |||
|sample_id=10052 | |||
|sample_note= | |||
|sample_sex=mixed | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=aorta | |||
|top_motifs=SRF:3.19810487178;ZIC1..3:3.18074717151;HMX1:2.74687626185;TBP:2.55609344912;TFAP2{A,C}:2.55120743481;GCM1,2:2.49336456426;GATA4:2.48363327819;XBP1:2.31936278872;TLX1..3_NFIC{dimer}:2.30621963538;TFAP4:2.21655626938;SPZ1:2.19415594443;MAZ:2.17529852778;PRDM1:2.1711885895;NKX2-1,4:2.09388131349;MEF2{A,B,C,D}:2.02157153317;TFCP2:1.98623359002;NFATC1..3:1.93447808859;SP1:1.91363373555;HBP1_HMGB_SSRP1_UBTF:1.79142913318;ZNF423:1.73496116201;ZNF384:1.72128888138;PATZ1:1.70113770736;MZF1:1.68010261673;AR:1.6727682217;MTE{core}:1.67231699652;TFAP2B:1.64063879197;TOPORS:1.63019579694;EP300:1.6195603118;ATF6:1.57413952101;IKZF1:1.51077578187;FOXO1,3,4:1.49942315803;HIC1:1.49251495854;STAT2,4,6:1.48205489394;MTF1:1.46101531109;FOX{D1,D2}:1.44530437964;T:1.43287487834;GTF2I:1.40911463037;GTF2A1,2:1.38883012099;MED-1{core}:1.38751833333;MYBL2:1.38324662538;TLX2:1.34825032683;RREB1:1.31474819555;FOXP1:1.29176354317;EGR1..3:1.27531934686;PITX1..3:1.24918982219;FOX{I1,J2}:1.24790868923;MYFfamily:1.21457777575;FOXL1:1.20546915524;SMAD1..7,9:1.192306693;XCPE1{core}:1.19041585144;RBPJ:1.15473996238;EBF1:1.14848872339;PAX5:1.12146993566;SOX5:1.11971527004;ALX4:1.0621224257;TEAD1:1.02182209582;RXRA_VDR{dimer}:0.993072617624;NR3C1:0.982661457912;ZNF238:0.97541128744;BPTF:0.948309073161;NR6A1:0.936348625302;BREu{core}:0.877072685012;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.870649322554;ZBTB6:0.863567791184;ATF2:0.844297621645;POU6F1:0.80728156643;LMO2:0.800852916094;KLF4:0.756854080978;ZFP161:0.742851070004;GLI1..3:0.718679388507;SNAI1..3:0.712793945129;TGIF1:0.682736775673;NR1H4:0.674346391695;UFEwm:0.669532459377;FOXA2:0.668829920799;GFI1B:0.655707795278;RXR{A,B,G}:0.594516387257;ATF4:0.561928898171;POU2F1..3:0.515771989187;POU5F1:0.512449325845;NFIL3:0.49553291759;JUN:0.438784730289;NHLH1,2:0.434184353338;HSF1,2:0.413991434834;ETS1,2:0.412808673337;IRF7:0.410604747074;HES1:0.406203657144;CREB1:0.398449981447;RFX1:0.386931420661;IKZF2:0.386153871005;REST:0.370750865661;RFX2..5_RFXANK_RFXAP:0.309337686877;ESRRA:0.284417471958;HAND1,2:0.233193360844;HIF1A:0.208316422617;ESR1:0.199980938814;AHR_ARNT_ARNT2:0.170324110571;IRF1,2:0.162888456229;STAT1,3:0.139747205536;ZBTB16:0.102507230977;ARID5B:0.0622101602747;GZF1:0.0269099355949;SPI1:0.0173367312947;HOX{A6,A7,B6,B7}:0.00755748580755;TP53:0.00245777029283;ZNF148:0.000308175521759;MAFB:-0.0123676692389;SREBF1,2:-0.0243790891146;CEBPA,B_DDIT3:-0.0695351100476;SPIB:-0.0724565881028;EVI1:-0.10587340448;NKX3-1:-0.106287576663;GATA6:-0.121822246731;VSX1,2:-0.12295628816;TBX4,5:-0.152794808381;HNF1A:-0.164711446252;ZEB1:-0.167222226018;SOX2:-0.217951935249;MYOD1:-0.226742188255;CDC5L:-0.229946057337;FOSL2:-0.23273356581;AIRE:-0.235421858785;NFE2L1:-0.255036710366;ATF5_CREB3:-0.258460070018;SOX{8,9,10}:-0.274855589248;FOXM1:-0.284918316984;ADNP_IRX_SIX_ZHX:-0.290909606091;FOXD3:-0.294071613906;RUNX1..3:-0.315832592566;NANOG{mouse}:-0.327000208809;POU3F1..4:-0.345979899231;NKX3-2:-0.351914549847;HNF4A_NR2F1,2:-0.361623226874;ELF1,2,4:-0.366807870592;LHX3,4:-0.375282854489;TEF:-0.379776843634;NFKB1_REL_RELA:-0.407564105616;PAX1,9:-0.418295701805;DBP:-0.435853740806;DMAP1_NCOR{1,2}_SMARC:-0.464266472634;FOX{F1,F2,J1}:-0.478058503298;FOXN1:-0.483288320631;TAL1_TCF{3,4,12}:-0.518576027741;HMGA1,2:-0.52220686485;TFDP1:-0.524874743053;FOXQ1:-0.525813997687;FOS_FOS{B,L1}_JUN{B,D}:-0.545673822093;BACH2:-0.579143650204;POU1F1:-0.586832373187;NFE2:-0.624904050546;HLF:-0.629789706236;CUX2:-0.635729535691;NANOG:-0.667807399473;PAX3,7:-0.696325803462;SOX17:-0.698531891217;NFY{A,B,C}:-0.705834550287;NFE2L2:-0.716709659817;PAX2:-0.737307102549;CDX1,2,4:-0.810796311471;PAX6:-0.909431853688;NR5A1,2:-0.924012096553;GFI1:-0.934742331895;PPARG:-0.939636466119;HOX{A5,B5}:-0.943002625504;ZNF143:-0.951018661999;ONECUT1,2:-0.96557002425;NKX2-2,8:-0.986772176984;NKX2-3_NKX2-5:-1.02254502626;OCT4_SOX2{dimer}:-1.0377401379;PRRX1,2:-1.05123171917;NRF1:-1.05856982563;RORA:-1.08490123289;FOXP3:-1.1033771477;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.11870768182;bHLH_family:-1.13036630212;NFIX:-1.14879880457;PBX1:-1.15352378567;HOX{A4,D4}:-1.16737745927;NKX6-1,2:-1.18123324497;LEF1_TCF7_TCF7L1,2:-1.33646834046;PAX4:-1.41959046315;E2F1..5:-1.44231262109;CRX:-1.51312180259;EN1,2:-1.62466840804;ALX1:-1.63399353051;HOXA9_MEIS1:-1.6400075841;PAX8:-1.70321793439;PDX1:-1.73311892916;STAT5{A,B}:-1.76302015302;MYB:-1.78844510544;ELK1,4_GABP{A,B1}:-2.0607637223;YY1:-2.38222353895 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10052-101G7;search_select_hide=table117:FF:10052-101G7 | |||
}} | }} |
Latest revision as of 12:17, 3 June 2020
Name: | aorta, adult, pool1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11760 |
Sample type: | tissues |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11760
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11760
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0211 |
10 | 10 | 0.0577 |
100 | 100 | 0.149 |
101 | 101 | 0.953 |
102 | 102 | 0.418 |
103 | 103 | 0.024 |
104 | 104 | 0.358 |
105 | 105 | 0.486 |
106 | 106 | 0.625 |
107 | 107 | 0.0849 |
108 | 108 | 0.538 |
109 | 109 | 0.024 |
11 | 11 | 0.132 |
110 | 110 | 0.127 |
111 | 111 | 0.0953 |
112 | 112 | 0.912 |
113 | 113 | 0.0592 |
114 | 114 | 0.0995 |
115 | 115 | 0.147 |
116 | 116 | 0.274 |
117 | 117 | 0.0156 |
118 | 118 | 0.0292 |
119 | 119 | 0.816 |
12 | 12 | 0.482 |
120 | 120 | 0.225 |
121 | 121 | 0.644 |
122 | 122 | 0.145 |
123 | 123 | 0.606 |
124 | 124 | 0.307 |
125 | 125 | 0.092 |
126 | 126 | 0.507 |
127 | 127 | 0.325 |
128 | 128 | 0.228 |
129 | 129 | 0.0353 |
13 | 13 | 0.0261 |
130 | 130 | 0.449 |
131 | 131 | 0.516 |
132 | 132 | 0.01 |
133 | 133 | 0.00218 |
134 | 134 | 0.107 |
135 | 135 | 0.303 |
136 | 136 | 0.404 |
137 | 137 | 0.453 |
138 | 138 | 0.995 |
139 | 139 | 0.704 |
14 | 14 | 0.963 |
140 | 140 | 0.812 |
141 | 141 | 0.245 |
142 | 142 | 0.238 |
143 | 143 | 0.0196 |
144 | 144 | 0.707 |
145 | 145 | 0.527 |
146 | 146 | 0.361 |
147 | 147 | 0.603 |
148 | 148 | 0.374 |
149 | 149 | 0.34 |
15 | 15 | 0.016 |
150 | 150 | 0.577 |
151 | 151 | 0.878 |
152 | 152 | 0.443 |
153 | 153 | 0.734 |
154 | 154 | 0.708 |
155 | 155 | 0.313 |
156 | 156 | 0.692 |
157 | 157 | 0.64 |
158 | 158 | 0.424 |
159 | 159 | 0.567 |
16 | 16 | 0.349 |
160 | 160 | 0.768 |
161 | 161 | 0.99 |
162 | 162 | 0.958 |
163 | 163 | 0.439 |
164 | 164 | 0.0994 |
165 | 165 | 0.742 |
166 | 166 | 0.091 |
167 | 167 | 0.0473 |
168 | 168 | 0.846 |
169 | 169 | 0.872 |
17 | 17 | 0.694 |
18 | 18 | 0.014 |
19 | 19 | 0.331 |
2 | 2 | 0.0468 |
20 | 20 | 0.105 |
21 | 21 | 0.395 |
22 | 22 | 0.863 |
23 | 23 | 0.241 |
24 | 24 | 0.133 |
25 | 25 | 0.386 |
26 | 26 | 0.164 |
27 | 27 | 0.848 |
28 | 28 | 0.7 |
29 | 29 | 0.00228 |
3 | 3 | 0.157 |
30 | 30 | 0.0504 |
31 | 31 | 0.834 |
32 | 32 | 0.674 |
33 | 33 | 0.109 |
34 | 34 | 0.328 |
35 | 35 | 0.154 |
36 | 36 | 0.00777 |
37 | 37 | 0.178 |
38 | 38 | 0.732 |
39 | 39 | 0.153 |
4 | 4 | 0.324 |
40 | 40 | 0.0658 |
41 | 41 | 0.06 |
42 | 42 | 0.178 |
43 | 43 | 0.2 |
44 | 44 | 0.822 |
45 | 45 | 0.408 |
46 | 46 | 0.149 |
47 | 47 | 0.0634 |
48 | 48 | 0.135 |
49 | 49 | 0.151 |
5 | 5 | 0.286 |
50 | 50 | 0.475 |
51 | 51 | 0.389 |
52 | 52 | 0.12 |
53 | 53 | 0.371 |
54 | 54 | 0.904 |
55 | 55 | 0.946 |
56 | 56 | 0.878 |
57 | 57 | 0.205 |
58 | 58 | 0.717 |
59 | 59 | 0.658 |
6 | 6 | 0.714 |
60 | 60 | 0.583 |
61 | 61 | 0.313 |
62 | 62 | 0.532 |
63 | 63 | 0.974 |
64 | 64 | 0.248 |
65 | 65 | 0.75 |
66 | 66 | 7.70921e-4 |
67 | 67 | 0.8 |
68 | 68 | 0.122 |
69 | 69 | 0.689 |
7 | 7 | 0.274 |
70 | 70 | 0.134 |
71 | 71 | 0.0238 |
72 | 72 | 0.338 |
73 | 73 | 0.266 |
74 | 74 | 0.469 |
75 | 75 | 0.00822 |
76 | 76 | 0.0205 |
77 | 77 | 0.0867 |
78 | 78 | 0.0147 |
79 | 79 | 0.393 |
8 | 8 | 0.205 |
80 | 80 | 0.6 |
81 | 81 | 0.657 |
82 | 82 | 0.9 |
83 | 83 | 0.922 |
84 | 84 | 0.867 |
85 | 85 | 0.252 |
86 | 86 | 0.775 |
87 | 87 | 0.00973 |
88 | 88 | 0.78 |
89 | 89 | 0.642 |
9 | 9 | 0.596 |
90 | 90 | 0.0159 |
91 | 91 | 0.496 |
92 | 92 | 0.522 |
93 | 93 | 0.00703 |
94 | 94 | 0.0144 |
95 | 95 | 0.00499 |
96 | 96 | 0.636 |
97 | 97 | 0.999 |
98 | 98 | 0.12 |
99 | 99 | 0.892 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11760
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0010052 human aorta - adult sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
UBERON: Anatomy
0000468 (multi-cellular organism)
0007023 (adult organism)
0000947 (aorta)
0001637 (artery)
0000483 (epithelium)
0000479 (tissue)
0000055 (vessel)
0004111 (anatomical conduit)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0003914 (epithelial tube)
0000025 (tube)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0004573 (systemic artery)
0003509 (arterial blood vessel)
0007500 (epithelial tube open at both ends)
0001981 (blood vessel)
0002049 (vasculature)
0010317 (germ layer / neural crest derived structure)
0007798 (vascular system)
0004535 (cardiovascular system)
0004571 (systemic arterial system)
0010191 (aortic system)
0004572 (arterial system)
0004537 (blood vasculature)
0001009 (circulatory system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000998 (adult tissue sample)
0000004 (tissue sample)
0010052 (human aorta - adult sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0002532 (epiblast (generic))
UBERON:0006603 (presumptive mesoderm)
UBERON:0004872 (splanchnic layer of lateral plate mesoderm)
UBERON:0006965 (vascular cord)
UBERON:0010316 (germ layer / neural crest)