FF:10789-110H6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005659 | ||
| | |accession_numbers=CAGE;DRX007772;DRR008644;DRZ000069;DRZ001454;DRZ011419;DRZ012804 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0101883,FF:0100740 | |||
| | |comment= | ||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr11:47400078..47400106,-!p1@SPI1!2.15!139.42!SPI1;;chr2:68592406..68592424,+!p1@PLEK!2.14!136.35!PLEK;;chr7:27205136..27205164,-!p1@HOXA9!2.14!136.16!HOXA9;;chr2:16080659..16080685,+!p1@MYCN!2.08!118.16!MYCN;;chr21:39870339..39870443,-!p1@ERG!2.05!110.31!ERG;;chr1:25256756..25256774,-!p1@RUNX3!1.90!144.40!RUNX3;;chr4:57522513..57522548,-!p4@HOPX!1.90!78.90!HOPX;;chr12:54694758..54694805,-!p1@NFE2!1.82!77.56!NFE2;;chr4:54966328..54966335,+!p1@GSX2!1.81!63.39!GSX2;;chr12:54694807..54694832,-!p3@NFE2!1.80!62.05!NFE2;;chr19:13213662..13213686,-!p1@LYL1!1.75!81.01!LYL1;;chr6:135502408..135502459,+!p2@MYB!1.74!62.24!MYB;;chr20:31350184..31350200,+!p1@DNMT3B!1.73!107.63!DNMT3B;;chr6:135502501..135502546,+!p1@MYB!1.68!56.30!MYB;;chr9:135854091..135854159,+!p1@GFI1B!1.63!42.13!GFI1B;;chr7:27205106..27205134,-!p2@HOXA9!1.58!37.34!HOXA9;;chr7:50344289..50344323,+!p1@IKZF1!1.58!37.15!IKZF1;;chr7:27213893..27213954,-!p1@HOXA10!1.52!31.79!HOXA10;;chr4:57522598..57522664,-!p3@HOPX!1.50!30.64!HOPX;;chr7:137620650..137620677,-!p3@CREB3L2!1.48!29.49!CREB3L2;;chr7:27192185..27192209,-!p1@HOXA3!1.44!26.24!HOXA3;;chr1:92951607..92951661,-!p1@GFI1!1.42!25.09!GFI1;;chr2:16082155..16082169,+!p3@MYCN!1.40!24.13!MYCN;;chr14:75988771..75988826,+!p1@BATF!1.39!30.83!BATF;;chr4:57522674..57522699,-!p5@HOPX!1.39!23.36!HOPX;;chr1:42384532..42384603,-!p2@HIVEP3!1.36!22.02!HIVEP3;;chr19:13213511..13213545,-!p2@LYL1!1.35!23.36!LYL1;;chr19:33793430..33793447,-!p1@CEBPA!1.32!81.58!CEBPA;;chr11:47400062..47400077,-!p2@SPI1!1.32!19.92!SPI1;;chr11:47399996..47400014,-!p4@SPI1!1.29!18.38!SPI1;;chrY:21906594..21906622,-!p1@KDM5D!1.27!17.81!KDM5D;;chr8:40755333..40755352,-!p1@ZMAT4!1.26!17.04!ZMAT4;;chr10:94449703..94449718,+!p1@HHEX!1.23!61.47!HHEX;;chr19:13213954..13214021,-!p4@LYL1!1.23!15.89!LYL1;;chr2:68592394..68592405,+!p2@PLEK!1.19!14.55!PLEK;;chr8:60031619..60031676,-!p1@TOX!1.18!30.26!TOX;;chr7:50344251..50344288,+!p3@IKZF1!1.15!13.02!IKZF1;;chr2:16080635..16080650,+!p4@MYCN!1.13!12.45!MYCN;;chr2:16081912..16081931,+!p2@MYCN!1.12!12.06!MYCN;;chr19:22235279..22235301,+!p1@ZNF257!1.11!22.60!ZNF257;;chr7:27196217..27196246,-!p2@HOXA7!1.11!11.87!HOXA7;;chr7:137620684..137620711,-!p4@CREB3L2!1.10!11.68!CREB3L2;;chr13:41593425..41593480,-!p1@ELF1!1.09!72.77!ELF1;;chr11:47399947..47399961,-!p3@SPI1!1.08!11.11!SPI1;;chr6:144385698..144385742,-!p2@PLAGL1!1.07!13.02!PLAGL1;;chr3:168864315..168864339,-!p2@MECOM!1.06!17.43!MECOM;;chr12:11802547..11802560,+!p5@ETV6!1.06!14.55!ETV6;;chr12:54778471..54778528,-!p1@ZNF385A!1.05!10.15!ZNF385A;;chr10:94449675..94449694,+!p2@HHEX!1.04!27.39!HHEX;;chr21:36421535..36421610,-!p2@RUNX1!0.98!31.41!RUNX1;;chr5:88178983..88179012,-!p1@MEF2C!0.97!65.88!MEF2C;;chr11:47400032..47400043,-!p5@SPI1!0.97!8.23!SPI1;;chr19:20011744..20011770,+!p1@ZNF93!0.96!32.75!ZNF93;;chr17:79881332..79881348,-!p3@MAFG!0.96!12.06!MAFG;;chr17:46622205..46622218,-!p3@HOXB2!0.96!9.58!HOXB2;;chr5:321810..321877,+!p1@AHRR!0.95!25.66!AHRR;;chr19:24097706..24097731,+!p2@ZNF726!0.95!15.32!ZNF726;;chr11:47400045..47400060,-!p6@SPI1!0.95!7.85!SPI1;;chr6:126240463..126240489,+!p6@NCOA7!0.94!8.81!NCOA7;;chr7:50343634..50343717,+!p2@IKZF1!0.93!7.47!IKZF1;;chr3:114819101..114819121,-!p7@ZBTB20!0.92!7.28!ZBTB20;;chr6:126240380..126240430,+!p2@NCOA7!0.91!19.15!NCOA7;;chr19:12203100..12203132,+!p1@ZNF788!0.91!14.94!ZNF788;;chr3:18486354..18486377,-!p2@SATB1!0.91!9.00!SATB1;;chr4:57522753..57522760,-!p18@HOPX!0.91!7.09!HOPX;;chr2:192015750..192015793,-!p2@STAT4!0.90!9.58!STAT4;;chr19:20188776..20188826,+!p1@ZNF90!0.89!18.77!ZNF90;;chr20:50159198..50159299,-!p1@NFATC2!0.88!9.96!NFATC2;;chr2:208031943..208031978,-!p5@KLF7!0.87!8.81!KLF7;;chr11:128563948..128564003,+!p1@FLI1!0.86!79.09!FLI1;;chr17:1959369..1959388,+!p2@HIC1!0.86!17.04!HIC1;;chr19:36391434..36391450,-!p1@NFKBID!0.86!12.83!NFKBID;;chr19:13213704..13213726,-!p3@LYL1!0.86!8.43!LYL1;;chr7:115670804..115670825,-!p1@TFEC!0.86!6.32!TFEC;;chr7:128577972..128578047,+!p1@IRF5!0.85!9.96!IRF5;;chr17:46622114..46622138,-!p4@HOXB2!0.85!9.58!HOXB2;;chr4:57522166..57522260,-!p2@HOPX!0.85!7.09!HOPX;;chr8:60031563..60031574,-!p7@TOX!0.85!6.13!TOX;;chr22:29196547..29196563,-!p2@XBP1!0.84!231.15!XBP1;;chr6:20402102..20402152,+!p1@E2F3!0.84!25.66!E2F3;;chr5:88179017..88179046,-!p2@MEF2C!0.84!25.28!MEF2C;;chr19:11959532..11959593,+!p1@ZNF439!0.84!23.94!ZNF439;;chr7:149470641..149470694,-!p1@ZNF467!0.83!27.58!ZNF467;;chr6:15246200..15246214,+!p2@JARID2!0.83!16.66!JARID2;;chr19:13213555..13213568,-!p5@LYL1!0.83!5.75!LYL1;;chr1:92949331..92949377,-!p2@GFI1!0.83!5.75!GFI1;;chr3:128212033..128212051,-!p1@GATA2!0.83!5.75!GATA2;;chr3:63953435..63953499,+!p1@ATXN7!0.83!5.75!ATXN7;;chr9:20382446..20382493,-!p4@MLLT3!0.83!5.75!MLLT3;;chr9:117150254..117150271,-!p1@AKNA!0.82!16.09!AKNA;;chr6:126240442..126240459,+!p4@NCOA7!0.82!7.28!NCOA7;;chr19:21106081..21106115,+!p2@ZNF85!0.80!16.85!ZNF85;;chr2:192015701..192015743,-!p1@STAT4!0.80!7.47!STAT4;;chr4:57522701..57522712,-!p10@HOPX!0.80!5.36!HOPX;;chr10:94451574..94451587,+!p6@HHEX!0.79!5.17!HHEX;;chr4:81118647..81118666,+!p1@PRDM8!0.78!6.89!PRDM8;;chr6:135502472..135502489,+!p3@MYB!0.78!4.98!MYB;;chr6:391743..391759,+!p1@IRF4!0.78!4.98!IRF4;;chr17:46622175..46622186,-!p12@HOXB2!0.78!4.98!HOXB2;;chr19:45579725..45579743,-!p1@ZNF296!0.77!23.75!ZNF296;;chr19:24097675..24097699,+!p1@ZNF726!0.77!17.43!ZNF726;;chr3:128206762..128206781,-!p2@GATA2!0.76!32.56!GATA2;;chr2:60780607..60780624,-!p2@BCL11A!0.76!15.89!BCL11A;;chr3:71355163..71355209,-!p5@FOXP1!0.76!6.89!FOXP1;;chr17:46622440..46622477,-!p5@HOXB2!0.76!5.36!HOXB2;;chr7:50348268..50348366,+!p4@IKZF1!0.76!4.79!IKZF1;;chr19:22034809..22034878,-!p2@ZNF43!0.75!17.81!ZNF43;;chr3:44626446..44626477,+!p1@ZNF660!0.75!8.81!ZNF660;;chr12:54785074..54785122,-!p2@ZNF385A!0.75!7.47!ZNF385A;;chr19:53039233..53039247,+!p2@ZNF808!0.75!7.09!ZNF808;;chr17:40440481..40440550,+!p1@STAT5A!0.74!36.00!STAT5A;;chr19:19976683..19976709,+!p1@ZNF253!0.74!21.83!ZNF253;;chr17:46622070..46622109,-!p1@HOXB2!0.74!10.72!HOXB2;;chr19:23299814..23299844,+!p1@ZNF730!0.73!5.55!ZNF730;;chr16:88752861..88752884,-!p2@SNAI3!0.73!4.40!SNAI3;;chr17:46655672..46655697,-!p3@HOXB4!0.73!4.40!HOXB4;;chr17:42295682..42295731,-!p17@UBTF!0.72!4.21!UBTF;;chr17:61920280..61920343,-!p2@SMARCD2!0.71!44.81!SMARCD2;;chr14:74226961..74227020,-!p1@C14orf43!0.71!30.45!C14orf43;;chr19:23433144..23433204,-!p1@ZNF724P!0.71!20.49!ZNF724P;;chr17:53342311..53342400,+!p1@HLF!0.71!4.79!HLF;;chr19:12551785..12551823,-!p1@ZNF443!0.70!6.89!ZNF443;;chr22:29196492..29196503,-!p3@XBP1!0.70!6.51!XBP1;;chr8:60031534..60031553,-!p8@TOX!0.70!4.02!TOX;;chr7:64838786..64838809,+!p2@ZNF92!0.69!25.09!ZNF92;;chr17:1958388..1958404,+!p1@HIC1!0.68!27.39!HIC1;;chr1:153940354..153940395,+!p1@CREB3L4!0.68!17.43!CREB3L4;;chr19:21950332..21950356,-!p2@ZNF100!0.68!8.81!ZNF100;;chrY:2803415..2803468,+!p1@ZFY!0.68!3.83!ZFY;;chr21:40177845..40177863,+!p1@ETS2!0.67!251.26!ETS2;;chr18:45457423..45457468,-!p5@SMAD2!0.67!15.32!SMAD2;;chr19:12551824..12551846,-!p2@ZNF443!0.67!5.17!ZNF443;;chr19:20011731..20011743,+!p3@ZNF93!0.67!4.98!ZNF93;;chr14:75988831..75988847,+!p2@BATF!0.67!3.64!BATF;;chr2:102091566..102091581,-!p1@RFX8!0.67!3.64!RFX8;;chr11:19262421..19262455,-!p3@E2F8!0.67!3.64!E2F8;;chr17:41277372..41277418,-!p1@BRCA1!0.66!14.75!BRCA1;;chr19:23941680..23941704,-!p1@ZNF681!0.66!11.68!ZNF681;;chr19:23941647..23941672,-!p2@ZNF681!0.66!6.32!ZNF681;;chr3:141747459..141747475,-!p1@TFDP2!0.65!33.70!TFDP2;;chr14:55493763..55493824,-!p1@WDHD1!0.65!30.45!WDHD1;;chr19:53073532..53073551,+!p1@ZNF701!0.65!18.00!ZNF701;;chr1:33004996..33005017,+!p3@ZBTB8A!0.65!4.98!ZBTB8A;;chr18:45457909..45457939,-!p8@SMAD2!0.65!4.40!SMAD2;;chr19:22235310..22235319,+!p2@ZNF257!0.65!3.45!ZNF257;;chr7:63505799..63505904,+!p1@ZNF727!0.65!3.45!ZNF727;;chr1:25291475..25291511,-!p2@RUNX3!0.65!3.45!RUNX3;;chr10:51572339..51572376,+!p4@NCOA4!0.64!8.43!NCOA4;;chr19:20748574..20748599,-!p1@ZNF737!0.63!22.98!ZNF737;;chr17:46655704..46655718,-!p2@HOXB4!0.63!5.17!HOXB4;;chr21:36421347..36421380,-!p8@RUNX1!0.63!3.26!RUNX1;;chr2:60781201..60781258,-!p3@BCL11A!0.63!3.26!BCL11A;;chr3:168865250..168865272,-!p5@MECOM!0.63!3.26!MECOM;;chr7:27205175..27205184,-!p3@HOXA9!0.63!3.26!HOXA9;;chr12:96588368..96588394,+!p3@ELK3!0.62!9.77!ELK3;;chr17:46621937..46621966,-!p2@HOXB2!0.62!9.77!HOXB2;;chr9:127533519..127533573,-!p2@NR6A1!0.62!4.02!NR6A1;;chr12:54785054..54785072,-!p4@ZNF385A!0.62!3.64!ZNF385A;;chr1:149858461..149858479,+!p1@BOLA1!0.61!1472.68!BOLA1;;chr2:145277640..145277771,-!p1@ZEB2!0.61!49.03!ZEB2;;chr10:105110831..105110885,-!p1@PCGF6!0.61!35.24!PCGF6;;chr19:23869970..23869991,-!p1@ZNF675!0.61!13.60!ZNF675;;chr19:12405606..12405629,-!p2@ZNF44!0.61!6.70!ZNF44;;chr2:217277271..217277290,+!p3@SMARCAL1!0.61!5.36!SMARCAL1;;chr10:45496320..45496336,+!p3@ZNF22!0.61!3.06!ZNF22;;chr12:54694653..54694672,-!p2@NFE2!0.61!3.06!NFE2;;chr19:21106049..21106072,+!p1@ZNF85!0.60!19.53!ZNF85;;chr15:57511609..57511651,+!p2@TCF12!0.60!5.55!TCF12;;chr3:168865194..168865245,-!p3@MECOM!0.60!4.02!MECOM;;chr12:11802600..11802685,+!p1@ETV6!0.59!52.86!ETV6;;chr10:51572408..51572454,+!p3@NCOA4!0.59!20.49!NCOA4;;chr2:121493425..121493474,+!p1@GLI2!0.59!7.28!GLI2;;chr19:19976714..19976729,+!p3@ZNF253!0.59!6.13!ZNF253;;chr1:23857698..23857733,-!p1@E2F2!0.59!5.94!E2F2;;chr10:94449649..94449664,+!p3@HHEX!0.59!4.60!HHEX;;chr19:12163769..12163798,-!p1@ZNF878!0.59!4.02!ZNF878;;chr17:45810594..45810608,+!p1@TBX21!0.59!2.87!TBX21;;chr18:55102598..55102623,+!p1@ONECUT2!0.59!2.87!ONECUT2;;chr6:15246741..15246765,+!p9@JARID2!0.59!2.87!JARID2;;chr14:45722360..45722415,-!p1@MIS18BP1!0.58!54.00!MIS18BP1;;chr5:176738887..176738934,-!p1@MXD3!0.58!22.79!MXD3;;chr12:11802575..11802592,+!p6@ETV6!0.58!4.40!ETV6;;chr6:31126291..31126399,+!p1@TCF19!0.57!32.17!TCF19;;chr11:130184470..130184533,-!p2@ZBTB44!0.57!8.62!ZBTB44;;chr19:13213634..13213645,-!p8@LYL1!0.57!2.68!LYL1;;chrY:21906761..21906810,-!p2@KDM5D!0.57!2.68!KDM5D;;chr19:6110474..6110551,-!p1@RFX2!0.56!19.53!RFX2;;chr16:3313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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.LQhCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M0%2529%2520cell%2520line%253aKasumi-3.CNhs13241.10789-110H6.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.LQhCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M0%2529%2520cell%2520line%253aKasumi-3.CNhs13241.10789-110H6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.LQhCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M0%2529%2520cell%2520line%253aKasumi-3.CNhs13241.10789-110H6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.LQhCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M0%2529%2520cell%2520line%253aKasumi-3.CNhs13241.10789-110H6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.LQhCAGE/acute%2520myeloid%2520leukemia%2520%2528FAB%2520M0%2529%2520cell%2520line%253aKasumi-3.CNhs13241.10789-110H6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10789-110H6 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0101883 | |||
|is_obsolete= | |||
|library_id=CNhs13241 | |||
|library_id_phase_based=2:CNhs13241 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10789 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10789 | |||
|name=acute myeloid leukemia (FAB M0) cell line:Kasumi-3 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13241,LSID1006,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,-0.277362132193514,-0.244355558547665,0,0,0,0,0,0,0,0,0,0,0.0760960040585542,0,0,-0.153323010348428,0,0,0,0,0,-0.0979578962680575,0,0,0.0641905189033015,0,0,0,0,0,0,0,0,0,0,0,0,-0.247541284470351,0,0,0,0,0,0,0,0,0.3177633728197,0,0,0,0.140825552791593,0,-0.043330089705205,0.0760960040585542,-0.0969923612426051,0,0,-0.0212476231545428,0,0,0,0,0,0,0,0,0,0,0.917883662366176,0,0,0.332242926988987,0,0,0,-0.0624110093031312,0.0380480020292771,0,0,0,0,-0.00636642453588654,-0.282245232202384,0,0,0,-0.0584468268118252,0.226656756850836,0,0,0,0,-0.0219393471791523,-0.100429198771618,0,0,0,0,0,0,0,0,0,0.0380480020292771,0,0,0,0,0,0,0,-0.0259608175266647,0,0,0,-0.207074288755302,-0.60393279483113,0,0,0,0,0,0 | |||
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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=0.03982 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=1.01 | |||
|rna_od260/280=1.9 | |||
|rna_position=H6 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=110H6 | |||
|rna_weight_ug=1.07514 | |||
|sample_age=57 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=jcrb1004 | |||
|sample_cell_line=Kasumi-3 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid progenitor cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=acute myeloid leukemia (FAB M0) | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=J | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;4.50584568653133e-245!GO:0043227;membrane-bound organelle;1.80907759678575e-223!GO:0043231;intracellular membrane-bound organelle;3.98824536625413e-223!GO:0043226;organelle;2.26969681590038e-205!GO:0043229;intracellular organelle;1.15746322049836e-204!GO:0005737;cytoplasm;1.24336822932221e-152!GO:0044422;organelle part;5.62407677584261e-144!GO:0044446;intracellular organelle part;4.2475798938623e-142!GO:0044444;cytoplasmic part;9.3701078840839e-118!GO:0044237;cellular metabolic process;1.97723962248059e-113!GO:0044238;primary metabolic process;1.51231473956571e-109!GO:0005634;nucleus;3.48142165924924e-108!GO:0032991;macromolecular complex;6.26597644213377e-108!GO:0043170;macromolecule metabolic process;1.12057843748186e-103!GO:0030529;ribonucleoprotein complex;5.3841348462969e-96!GO:0044428;nuclear part;1.2100763758904e-83!GO:0043233;organelle lumen;1.24948840014688e-80!GO:0031974;membrane-enclosed lumen;1.24948840014688e-80!GO:0003723;RNA binding;3.69854680518767e-79!GO:0005739;mitochondrion;7.86624104835799e-76!GO:0043283;biopolymer metabolic process;5.56054918114585e-65!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.72829812968186e-63!GO:0010467;gene expression;1.30636341035793e-57!GO:0006396;RNA processing;4.83095141110426e-57!GO:0005515;protein binding;6.76432012919215e-56!GO:0005840;ribosome;1.03245662072363e-55!GO:0006412;translation;2.02942660624381e-54!GO:0043234;protein complex;4.52328217891937e-53!GO:0031981;nuclear lumen;4.0692032184322e-50!GO:0044429;mitochondrial part;4.9570544417881e-50!GO:0003735;structural constituent of ribosome;7.72255996748809e-49!GO:0006259;DNA metabolic process;1.00566336927132e-48!GO:0019538;protein metabolic process;9.7750682785192e-48!GO:0016071;mRNA metabolic process;1.30350180225004e-45!GO:0044267;cellular protein metabolic process;1.89886292104854e-44!GO:0009058;biosynthetic process;8.35060670836655e-44!GO:0044260;cellular macromolecule metabolic process;9.28548913184738e-44!GO:0044249;cellular biosynthetic process;1.66051424095534e-43!GO:0009059;macromolecule biosynthetic process;5.72851222877476e-42!GO:0031967;organelle envelope;1.32091349336342e-41!GO:0031975;envelope;3.15632442708322e-41!GO:0033279;ribosomal subunit;4.36403323331794e-41!GO:0008380;RNA splicing;6.37228105951614e-41!GO:0031090;organelle membrane;1.566212426594e-40!GO:0005829;cytosol;5.39284694255365e-40!GO:0003676;nucleic acid binding;7.94432008180912e-40!GO:0006397;mRNA processing;9.97354891694305e-40!GO:0033036;macromolecule localization;2.34843175186483e-39!GO:0016043;cellular component organization and biogenesis;3.70797563716829e-38!GO:0015031;protein transport;7.96006664796273e-38!GO:0045184;establishment of protein localization;1.33741492994123e-35!GO:0065003;macromolecular complex assembly;1.35728689532129e-35!GO:0008104;protein localization;3.71610973646556e-35!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.19336299317749e-32!GO:0005654;nucleoplasm;4.28553898036392e-32!GO:0006996;organelle organization and biogenesis;8.67799718692732e-32!GO:0005681;spliceosome;3.4549047790349e-31!GO:0007049;cell cycle;1.14693103956418e-30!GO:0005740;mitochondrial envelope;1.64566448251911e-30!GO:0022607;cellular component assembly;1.80918527553533e-30!GO:0043228;non-membrane-bound organelle;2.7909704498615e-30!GO:0043232;intracellular non-membrane-bound organelle;2.7909704498615e-30!GO:0019866;organelle inner membrane;3.3032483939331e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);6.88007290111368e-30!GO:0005694;chromosome;1.32309439666888e-29!GO:0046907;intracellular transport;2.75480675700211e-29!GO:0031966;mitochondrial membrane;2.34670126207238e-28!GO:0016070;RNA metabolic process;3.50050413606157e-28!GO:0006886;intracellular protein transport;4.02511050584282e-28!GO:0006974;response to DNA damage stimulus;4.38085966507762e-28!GO:0005743;mitochondrial inner membrane;2.45250193678548e-27!GO:0044427;chromosomal part;7.93034014784909e-27!GO:0044445;cytosolic part;5.67734342126078e-26!GO:0000166;nucleotide binding;2.10434554340252e-25!GO:0006281;DNA repair;3.50133706576113e-25!GO:0022402;cell cycle process;1.06207551463921e-24!GO:0044451;nucleoplasm part;7.90638213370901e-24!GO:0006119;oxidative phosphorylation;9.13055147995135e-24!GO:0031980;mitochondrial lumen;2.60338990118599e-23!GO:0005759;mitochondrial matrix;2.60338990118599e-23!GO:0051276;chromosome organization and biogenesis;7.08673231087101e-23!GO:0015935;small ribosomal subunit;4.19137346925015e-22!GO:0051649;establishment of cellular localization;7.79815550089929e-22!GO:0000278;mitotic cell cycle;1.29318439523387e-21!GO:0051641;cellular localization;2.86544515474974e-21!GO:0044455;mitochondrial membrane part;4.36334728082705e-21!GO:0015934;large ribosomal subunit;4.08340913956491e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.30020209514355e-20!GO:0016462;pyrophosphatase activity;6.5108205773135e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;6.56223732299119e-20!GO:0017111;nucleoside-triphosphatase activity;2.14951351553589e-19!GO:0009719;response to endogenous stimulus;4.402991072552e-19!GO:0022618;protein-RNA complex assembly;7.29493108281295e-19!GO:0005730;nucleolus;7.46252359811929e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;9.06631804918758e-19!GO:0006457;protein folding;1.01033641712071e-18!GO:0006323;DNA packaging;4.6813513939091e-18!GO:0000087;M phase of mitotic cell cycle;6.74338415588836e-18!GO:0032553;ribonucleotide binding;1.14502048592723e-17!GO:0032555;purine ribonucleotide binding;1.14502048592723e-17!GO:0044265;cellular macromolecule catabolic process;1.23135034557752e-17!GO:0006260;DNA replication;1.55119426742164e-17!GO:0048770;pigment granule;1.69308059823007e-17!GO:0042470;melanosome;1.69308059823007e-17!GO:0022403;cell cycle phase;1.79404044799673e-17!GO:0007067;mitosis;2.18018091880316e-17!GO:0000502;proteasome complex (sensu Eukaryota);4.70401542233881e-17!GO:0005746;mitochondrial respiratory chain;5.33713207470091e-17!GO:0017076;purine nucleotide binding;7.34290928753341e-17!GO:0005761;mitochondrial ribosome;1.95729661094972e-16!GO:0000313;organellar ribosome;1.95729661094972e-16!GO:0051301;cell division;2.06608971405929e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.22112642592508e-16!GO:0016874;ligase activity;2.2897558843165e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.32181912400092e-16!GO:0005524;ATP binding;3.20125874164057e-16!GO:0032559;adenyl ribonucleotide binding;4.50873472869033e-16!GO:0006512;ubiquitin cycle;4.79688653820127e-16!GO:0051186;cofactor metabolic process;6.71872177160632e-16!GO:0042623;ATPase activity, coupled;7.26849731143168e-16!GO:0050136;NADH dehydrogenase (quinone) activity;9.49020119794925e-16!GO:0003954;NADH dehydrogenase activity;9.49020119794925e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;9.49020119794925e-16!GO:0000785;chromatin;1.29202433964036e-15!GO:0016604;nuclear body;1.33682163487579e-15!GO:0044248;cellular catabolic process;1.39463784896112e-15!GO:0043285;biopolymer catabolic process;1.77968432282163e-15!GO:0016887;ATPase activity;2.20479024127509e-15!GO:0006605;protein targeting;2.64533296031533e-15!GO:0000279;M phase;3.48720400811161e-15!GO:0030554;adenyl nucleotide binding;4.15531291468104e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;6.10984480753587e-15!GO:0006511;ubiquitin-dependent protein catabolic process;7.28545411930578e-15!GO:0019941;modification-dependent protein catabolic process;7.28545411930578e-15!GO:0043632;modification-dependent macromolecule catabolic process;7.28545411930578e-15!GO:0009057;macromolecule catabolic process;8.61095582725747e-15!GO:0042254;ribosome biogenesis and assembly;9.88155754610672e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.00169336011913e-14!GO:0000375;RNA splicing, via transesterification reactions;1.00169336011913e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.00169336011913e-14!GO:0065004;protein-DNA complex assembly;1.23962537732543e-14!GO:0044257;cellular protein catabolic process;1.55465418338731e-14!GO:0043412;biopolymer modification;1.55465418338731e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);4.01833411225781e-14!GO:0042775;organelle ATP synthesis coupled electron transport;4.29803778410298e-14!GO:0042773;ATP synthesis coupled electron transport;4.29803778410298e-14!GO:0051726;regulation of cell cycle;5.17278301236322e-14!GO:0008135;translation factor activity, nucleic acid binding;5.94010151179995e-14!GO:0000074;regulation of progression through cell cycle;7.15018752007343e-14!GO:0006333;chromatin assembly or disassembly;7.65004964515978e-14!GO:0030964;NADH dehydrogenase complex (quinone);9.37508833901276e-14!GO:0045271;respiratory chain complex I;9.37508833901276e-14!GO:0005747;mitochondrial respiratory chain complex I;9.37508833901276e-14!GO:0006913;nucleocytoplasmic transport;1.56428841472372e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.12017035762428e-13!GO:0008134;transcription factor binding;3.3601436445082e-13!GO:0051169;nuclear transport;3.77069401059277e-13!GO:0006732;coenzyme metabolic process;4.42526918820317e-13!GO:0006915;apoptosis;6.39674545123971e-13!GO:0012501;programmed cell death;6.59015633710433e-13!GO:0012505;endomembrane system;7.69333585170155e-13!GO:0044453;nuclear membrane part;1.18845996584083e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.42658221678378e-12!GO:0016607;nuclear speck;1.59411925546614e-12!GO:0003743;translation initiation factor activity;3.41379845903748e-12!GO:0009259;ribonucleotide metabolic process;3.48227432980053e-12!GO:0006163;purine nucleotide metabolic process;3.8229981731925e-12!GO:0006464;protein modification process;3.88934080082567e-12!GO:0050657;nucleic acid transport;3.89481833744645e-12!GO:0051236;establishment of RNA localization;3.89481833744645e-12!GO:0050658;RNA transport;3.89481833744645e-12!GO:0006403;RNA localization;4.81999178958265e-12!GO:0031965;nuclear membrane;4.87111399327411e-12!GO:0030163;protein catabolic process;5.8829462673315e-12!GO:0004386;helicase activity;7.20734125304944e-12!GO:0008219;cell death;1.01808737174469e-11!GO:0016265;death;1.01808737174469e-11!GO:0006164;purine nucleotide biosynthetic process;1.04380702642258e-11!GO:0006413;translational initiation;1.11917429507224e-11!GO:0051082;unfolded protein binding;1.29068346085849e-11!GO:0016568;chromatin modification;1.34964060440371e-11!GO:0005635;nuclear envelope;1.59146181655476e-11!GO:0009260;ribonucleotide biosynthetic process;2.86246733850707e-11!GO:0044432;endoplasmic reticulum part;2.88591310936485e-11!GO:0006334;nucleosome assembly;3.93961232957746e-11!GO:0009150;purine ribonucleotide metabolic process;5.33870414408385e-11!GO:0017038;protein import;5.35306304515712e-11!GO:0031497;chromatin assembly;5.80619143799581e-11!GO:0050794;regulation of cellular process;1.3214467987957e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.3818450172325e-10!GO:0005783;endoplasmic reticulum;1.49919519247729e-10!GO:0009152;purine ribonucleotide biosynthetic process;1.49949742623102e-10!GO:0008026;ATP-dependent helicase activity;1.51260540398598e-10!GO:0016787;hydrolase activity;1.67884283659373e-10!GO:0006446;regulation of translational initiation;1.91902163616139e-10!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.10216028133789e-10!GO:0005643;nuclear pore;2.15009531482335e-10!GO:0006364;rRNA processing;2.38909413850954e-10!GO:0016072;rRNA metabolic process;3.22776508779223e-10!GO:0051028;mRNA transport;3.25152253573993e-10!GO:0043687;post-translational protein modification;3.5359833828955e-10!GO:0009055;electron carrier activity;3.67884800662846e-10!GO:0019829;cation-transporting ATPase activity;3.94827917068222e-10!GO:0043566;structure-specific DNA binding;4.38858719360696e-10!GO:0065002;intracellular protein transport across a membrane;4.45277197333949e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.47380542181536e-10!GO:0006399;tRNA metabolic process;8.11794581540852e-10!GO:0003697;single-stranded DNA binding;1.0355320970685e-09!GO:0000775;chromosome, pericentric region;1.57042237542908e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.5946265987084e-09!GO:0016192;vesicle-mediated transport;1.96598639016303e-09!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.08915148229601e-09!GO:0006261;DNA-dependent DNA replication;2.47570582906984e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.58238160980995e-09!GO:0008565;protein transporter activity;2.64590567335136e-09!GO:0051188;cofactor biosynthetic process;2.70776453186781e-09!GO:0009199;ribonucleoside triphosphate metabolic process;2.9741205351012e-09!GO:0009141;nucleoside triphosphate metabolic process;3.21361320383603e-09!GO:0015986;ATP synthesis coupled proton transport;3.75805956401969e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.75805956401969e-09!GO:0009056;catabolic process;3.78395630845509e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;5.88810470863404e-09!GO:0009144;purine nucleoside triphosphate metabolic process;5.88810470863404e-09!GO:0009060;aerobic respiration;6.18366432721675e-09!GO:0009142;nucleoside triphosphate biosynthetic process;6.18366432721675e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;6.18366432721675e-09!GO:0016779;nucleotidyltransferase activity;7.35698477077837e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;8.07193318007619e-09!GO:0009117;nucleotide metabolic process;9.53550016470436e-09!GO:0048193;Golgi vesicle transport;1.26100455404234e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.26454014323031e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.26454014323031e-08!GO:0019222;regulation of metabolic process;1.36511802054111e-08!GO:0046930;pore complex;1.53469481156443e-08!GO:0005789;endoplasmic reticulum membrane;1.74460566318406e-08!GO:0005819;spindle;1.84824121668033e-08!GO:0005773;vacuole;2.46841597739661e-08!GO:0042981;regulation of apoptosis;2.76482145163995e-08!GO:0006793;phosphorus metabolic process;2.98930225088011e-08!GO:0006796;phosphate metabolic process;2.98930225088011e-08!GO:0046034;ATP metabolic process;3.29699536580013e-08!GO:0003712;transcription cofactor activity;3.52639641522342e-08!GO:0015078;hydrogen ion transmembrane transporter activity;3.5860379252569e-08!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.65448284584853e-08!GO:0005839;proteasome core complex (sensu Eukaryota);4.16728736617161e-08!GO:0043067;regulation of programmed cell death;4.16728736617161e-08!GO:0006754;ATP biosynthetic process;5.37864185822369e-08!GO:0006753;nucleoside phosphate metabolic process;5.37864185822369e-08!GO:0000323;lytic vacuole;5.37864185822369e-08!GO:0005764;lysosome;5.37864185822369e-08!GO:0006461;protein complex assembly;7.35414537489333e-08!GO:0008639;small protein conjugating enzyme activity;7.40912450832388e-08!GO:0045333;cellular respiration;7.93779188035019e-08!GO:0016469;proton-transporting two-sector ATPase complex;8.043503460297e-08!GO:0000786;nucleosome;8.63842990955931e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;9.51132117666846e-08!GO:0006099;tricarboxylic acid cycle;1.1829002432786e-07!GO:0046356;acetyl-CoA catabolic process;1.1829002432786e-07!GO:0005793;ER-Golgi intermediate compartment;1.358807541392e-07!GO:0051246;regulation of protein metabolic process;1.358807541392e-07!GO:0051170;nuclear import;1.37415239555683e-07!GO:0009108;coenzyme biosynthetic process;1.50485176396967e-07!GO:0006752;group transfer coenzyme metabolic process;1.58359223210946e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.64883180564219e-07!GO:0004842;ubiquitin-protein ligase activity;1.66295677064192e-07!GO:0006606;protein import into nucleus;2.05561473298668e-07!GO:0016310;phosphorylation;2.1726827379245e-07!GO:0019787;small conjugating protein ligase activity;2.88368046514211e-07!GO:0006084;acetyl-CoA metabolic process;2.9921079336558e-07!GO:0006366;transcription from RNA polymerase II promoter;3.2445139836508e-07!GO:0004298;threonine endopeptidase activity;3.27724887883111e-07!GO:0000245;spliceosome assembly;4.58202912219967e-07!GO:0005657;replication fork;5.65545200268819e-07!GO:0005768;endosome;6.34612450353056e-07!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;6.35602636869138e-07!GO:0005794;Golgi apparatus;7.26256908007059e-07!GO:0045259;proton-transporting ATP synthase complex;7.31014451145578e-07!GO:0008094;DNA-dependent ATPase activity;7.61801191165509e-07!GO:0050789;regulation of biological process;7.66053220886862e-07!GO:0031323;regulation of cellular metabolic process;8.25790138643457e-07!GO:0005813;centrosome;8.71314121002794e-07!GO:0006310;DNA recombination;1.11176235036284e-06!GO:0005815;microtubule organizing center;1.23454300932939e-06!GO:0000075;cell cycle checkpoint;1.35801893292473e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.55523477433368e-06!GO:0016881;acid-amino acid ligase activity;1.65732118417023e-06!GO:0016740;transferase activity;1.79285937288625e-06!GO:0009109;coenzyme catabolic process;1.85524922935592e-06!GO:0005762;mitochondrial large ribosomal subunit;2.00817979513947e-06!GO:0000315;organellar large ribosomal subunit;2.00817979513947e-06!GO:0007051;spindle organization and biogenesis;2.92416979318453e-06!GO:0003899;DNA-directed RNA polymerase activity;3.51943829751626e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.64465018862757e-06!GO:0007243;protein kinase cascade;3.7812125272374e-06!GO:0007005;mitochondrion organization and biogenesis;4.12076503071533e-06!GO:0006950;response to stress;4.173662280055e-06!GO:0051187;cofactor catabolic process;4.36320244742377e-06!GO:0032446;protein modification by small protein conjugation;4.40307854835476e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;4.46054363135323e-06!GO:0003690;double-stranded DNA binding;4.69783317142415e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;5.54208943861534e-06!GO:0004812;aminoacyl-tRNA ligase activity;5.54208943861534e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;5.54208943861534e-06!GO:0009165;nucleotide biosynthetic process;5.76718779871342e-06!GO:0045786;negative regulation of progression through cell cycle;5.784759280983e-06!GO:0051329;interphase of mitotic cell cycle;6.35715708753243e-06!GO:0015630;microtubule cytoskeleton;6.5783917944009e-06!GO:0006350;transcription;8.1008618403553e-06!GO:0043038;amino acid activation;8.53187160977289e-06!GO:0006418;tRNA aminoacylation for protein translation;8.53187160977289e-06!GO:0043039;tRNA aminoacylation;8.53187160977289e-06!GO:0006613;cotranslational protein targeting to membrane;8.96687558639748e-06!GO:0016567;protein ubiquitination;9.30257982855602e-06!GO:0006302;double-strand break repair;9.56683771920256e-06!GO:0003713;transcription coactivator activity;9.77079128760339e-06!GO:0051325;interphase;1.05763563137671e-05!GO:0005770;late endosome;1.28245580622249e-05!GO:0065009;regulation of a molecular function;1.52441960386242e-05!GO:0051168;nuclear export;1.62177253040627e-05!GO:0003724;RNA helicase activity;1.66307848957634e-05!GO:0006888;ER to Golgi vesicle-mediated transport;2.03377125771882e-05!GO:0016363;nuclear matrix;2.18250218786506e-05!GO:0043069;negative regulation of programmed cell death;2.31849761813791e-05!GO:0016491;oxidoreductase activity;2.39343082729025e-05!GO:0006401;RNA catabolic process;2.47631570796414e-05!GO:0008654;phospholipid biosynthetic process;2.52446482190536e-05!GO:0010468;regulation of gene expression;2.56697659496892e-05!GO:0048523;negative regulation of cellular process;2.56697659496892e-05!GO:0000776;kinetochore;2.68348238949889e-05!GO:0043066;negative regulation of apoptosis;3.00866837119436e-05!GO:0003684;damaged DNA binding;3.68444091228833e-05!GO:0000151;ubiquitin ligase complex;4.17216212555243e-05!GO:0003677;DNA binding;4.2358418556486e-05!GO:0006352;transcription initiation;4.37802544090842e-05!GO:0007088;regulation of mitosis;4.58699914308254e-05!GO:0043623;cellular protein complex assembly;4.63943751353267e-05!GO:0000314;organellar small ribosomal subunit;4.91926435516368e-05!GO:0005763;mitochondrial small ribosomal subunit;4.91926435516368e-05!GO:0007059;chromosome segregation;4.96745364102045e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;4.9882436042206e-05!GO:0015399;primary active transmembrane transporter activity;4.9882436042206e-05!GO:0031324;negative regulation of cellular metabolic process;5.87841622337127e-05!GO:0003678;DNA helicase activity;6.61865184207794e-05!GO:0004518;nuclease activity;6.78879370525156e-05!GO:0048475;coated membrane;7.33774268162887e-05!GO:0030117;membrane coat;7.33774268162887e-05!GO:0043681;protein import into mitochondrion;7.39951702435629e-05!GO:0006612;protein targeting to membrane;7.97316306690324e-05!GO:0003729;mRNA binding;8.21301002181346e-05!GO:0019843;rRNA binding;8.46996741366152e-05!GO:0030120;vesicle coat;8.47284898832908e-05!GO:0030662;coated vesicle membrane;8.47284898832908e-05!GO:0006916;anti-apoptosis;8.47284898832908e-05!GO:0005667;transcription factor complex;8.69310511000429e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;9.28901979794357e-05!GO:0008033;tRNA processing;9.50175964785136e-05!GO:0044440;endosomal part;9.74521938524481e-05!GO:0010008;endosome membrane;9.74521938524481e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;9.9012406272537e-05!GO:0043021;ribonucleoprotein binding;0.000117616657868346!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000123198141500445!GO:0005885;Arp2/3 protein complex;0.000146329649594093!GO:0006818;hydrogen transport;0.000153407849818515!GO:0051087;chaperone binding;0.000153968343243276!GO:0015992;proton transport;0.000169077363564374!GO:0019899;enzyme binding;0.00017286137502422!GO:0065007;biological regulation;0.000177859831448431!GO:0044452;nucleolar part;0.000181031367304663!GO:0006402;mRNA catabolic process;0.000203161447022263!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000212623357412605!GO:0016853;isomerase activity;0.000212623357412605!GO:0051427;hormone receptor binding;0.000218381095308553!GO:0048519;negative regulation of biological process;0.000227930011351436!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000254302767681172!GO:0008632;apoptotic program;0.00025833205530063!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00031414329070479!GO:0016563;transcription activator activity;0.000314231181482406!GO:0006417;regulation of translation;0.000318304268029657!GO:0007093;mitotic cell cycle checkpoint;0.000324534374329537!GO:0006091;generation of precursor metabolites and energy;0.000339826265943528!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000343210595929817!GO:0008186;RNA-dependent ATPase activity;0.000355944186829069!GO:0006383;transcription from RNA polymerase III promoter;0.00038096900171129!GO:0009892;negative regulation of metabolic process;0.000381755867801222!GO:0016564;transcription repressor activity;0.000400209894380146!GO:0008168;methyltransferase activity;0.000440157921917251!GO:0035257;nuclear hormone receptor binding;0.00044162998736011!GO:0046489;phosphoinositide biosynthetic process;0.000470391548467817!GO:0032774;RNA biosynthetic process;0.000471619399660013!GO:0045454;cell redox homeostasis;0.00047551806354377!GO:0016741;transferase activity, transferring one-carbon groups;0.00048046673638599!GO:0006405;RNA export from nucleus;0.000490463654024624!GO:0046474;glycerophospholipid biosynthetic process;0.000497137122065776!GO:0005769;early endosome;0.000508960915206711!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000516423703479196!GO:0042802;identical protein binding;0.000541277621782835!GO:0009116;nucleoside metabolic process;0.000556411883667865!GO:0043492;ATPase activity, coupled to movement of substances;0.000559976141791907!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000573136280478907!GO:0032508;DNA duplex unwinding;0.000582848157755182!GO:0032392;DNA geometric change;0.000582848157755182!GO:0005788;endoplasmic reticulum lumen;0.000596932897952745!GO:0016859;cis-trans isomerase activity;0.000609385867885854!GO:0030880;RNA polymerase complex;0.000610476404872961!GO:0005525;GTP binding;0.000623060919399794!GO:0006351;transcription, DNA-dependent;0.000626279429320304!GO:0030384;phosphoinositide metabolic process;0.000628911139571254!GO:0000922;spindle pole;0.00064317961009226!GO:0000287;magnesium ion binding;0.000660466418088323!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000668051619446882!GO:0007006;mitochondrial membrane organization and biogenesis;0.000670904841839755!GO:0031072;heat shock protein binding;0.000683148317665512!GO:0005684;U2-dependent spliceosome;0.000722450241750763!GO:0006414;translational elongation;0.000786044563289748!GO:0051052;regulation of DNA metabolic process;0.000805652866323813!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000807983418778824!GO:0046483;heterocycle metabolic process;0.000835720733357708!GO:0043065;positive regulation of apoptosis;0.000901979923871258!GO:0005637;nuclear inner membrane;0.000994212087804674!GO:0004004;ATP-dependent RNA helicase activity;0.000995630934232268!GO:0016251;general RNA polymerase II transcription factor activity;0.00102746620628233!GO:0050790;regulation of catalytic activity;0.00110507095540083!GO:0006650;glycerophospholipid metabolic process;0.00113684786255877!GO:0006917;induction of apoptosis;0.00114827553121368!GO:0004527;exonuclease activity;0.00115548026329761!GO:0016481;negative regulation of transcription;0.00116096504623812!GO:0007052;mitotic spindle organization and biogenesis;0.00116391718206252!GO:0003924;GTPase activity;0.0012180237650848!GO:0007242;intracellular signaling cascade;0.00121892917244686!GO:0043068;positive regulation of programmed cell death;0.00124713213919955!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00133317049965624!GO:0000428;DNA-directed RNA polymerase complex;0.00133317049965624!GO:0046822;regulation of nucleocytoplasmic transport;0.0013750647226972!GO:0005798;Golgi-associated vesicle;0.00138717113124333!GO:0006284;base-excision repair;0.00149228456595018!GO:0006268;DNA unwinding during replication;0.00158362527519261!GO:0012502;induction of programmed cell death;0.00159202454458474!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.001617371317904!GO:0045449;regulation of transcription;0.00165776208985329!GO:0006082;organic acid metabolic process;0.0017281297922328!GO:0047485;protein N-terminus binding;0.00173492593010281!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00174287113147009!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00174287113147009!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00177656951269051!GO:0019752;carboxylic acid metabolic process;0.00189365645967974!GO:0031326;regulation of cellular biosynthetic process;0.00189604019219919!GO:0000228;nuclear chromosome;0.00190526222677692!GO:0003682;chromatin binding;0.0019814173992942!GO:0051252;regulation of RNA metabolic process;0.0020549134909715!GO:0042393;histone binding;0.00206615811596267!GO:0015980;energy derivation by oxidation of organic compounds;0.00213402705536082!GO:0005876;spindle microtubule;0.00215431576321195!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00217109323600011!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00217109323600011!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00217109323600011!GO:0048500;signal recognition particle;0.00223261426064982!GO:0006626;protein targeting to mitochondrion;0.00225686095382554!GO:0031988;membrane-bound vesicle;0.00238634521528417!GO:0031982;vesicle;0.00239981613855444!GO:0022890;inorganic cation transmembrane transporter activity;0.00241989471766086!GO:0009967;positive regulation of signal transduction;0.00266678557686219!GO:0031252;leading edge;0.00266747552464378!GO:0046467;membrane lipid biosynthetic process;0.00266747552464378!GO:0006338;chromatin remodeling;0.00274306200314227!GO:0051540;metal cluster binding;0.00274434345843986!GO:0051536;iron-sulfur cluster binding;0.00274434345843986!GO:0006506;GPI anchor biosynthetic process;0.002876669499048!GO:0051287;NAD binding;0.00291206084653033!GO:0005774;vacuolar membrane;0.0030905069833638!GO:0015036;disulfide oxidoreductase activity;0.00309975227725638!GO:0006289;nucleotide-excision repair;0.00330639542406325!GO:0007050;cell cycle arrest;0.00353417820759868!GO:0043488;regulation of mRNA stability;0.00360204059588279!GO:0043487;regulation of RNA stability;0.00360204059588279!GO:0008312;7S RNA binding;0.00367334120084445!GO:0003711;transcription elongation regulator activity;0.00367987457004743!GO:0000096;sulfur amino acid metabolic process;0.00375390364600089!GO:0009112;nucleobase metabolic process;0.00395524941776434!GO:0009124;nucleoside monophosphate biosynthetic process;0.00409969590497295!GO:0009123;nucleoside monophosphate metabolic process;0.00409969590497295!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00420387659128699!GO:0043414;biopolymer methylation;0.00421110935907059!GO:0043596;nuclear replication fork;0.00421336263056338!GO:0000082;G1/S transition of mitotic cell cycle;0.00428624977125129!GO:0031124;mRNA 3'-end processing;0.00450380164210116!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00451146920080588!GO:0006505;GPI anchor metabolic process;0.00453609540164248!GO:0016023;cytoplasmic membrane-bound vesicle;0.00469182289577515!GO:0031968;organelle outer membrane;0.00483987851709564!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00494597572552317!GO:0045047;protein targeting to ER;0.00494597572552317!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00521996325922652!GO:0015002;heme-copper terminal oxidase activity;0.00521996325922652!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00521996325922652!GO:0004129;cytochrome-c oxidase activity;0.00521996325922652!GO:0022411;cellular component disassembly;0.00530957770923867!GO:0030867;rough endoplasmic reticulum membrane;0.00532945447727438!GO:0031902;late endosome membrane;0.00546929209976485!GO:0032561;guanyl ribonucleotide binding;0.00547935527473965!GO:0019001;guanyl nucleotide binding;0.00547935527473965!GO:0048487;beta-tubulin binding;0.00586305100984947!GO:0030521;androgen receptor signaling pathway;0.00586382546373019!GO:0031410;cytoplasmic vesicle;0.0062424103461719!GO:0005758;mitochondrial intermembrane space;0.00629707250928575!GO:0019867;outer membrane;0.00629715347803521!GO:0015631;tubulin binding;0.00630670073677205!GO:0040029;regulation of gene expression, epigenetic;0.00644138722405085!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00646029104116814!GO:0006497;protein amino acid lipidation;0.0065703343965355!GO:0051539;4 iron, 4 sulfur cluster binding;0.00659492691795084!GO:0005048;signal sequence binding;0.00671218976294553!GO:0000178;exosome (RNase complex);0.00677894461794336!GO:0004003;ATP-dependent DNA helicase activity;0.00677894461794336!GO:0008234;cysteine-type peptidase activity;0.00680543033113923!GO:0003714;transcription corepressor activity;0.00684692470226068!GO:0031570;DNA integrity checkpoint;0.00705920025602903!GO:0032984;macromolecular complex disassembly;0.00705920025602903!GO:0006839;mitochondrial transport;0.00711066778542101!GO:0044437;vacuolar part;0.00716504151322372!GO:0032259;methylation;0.007222009341108!GO:0005741;mitochondrial outer membrane;0.00737091907343036!GO:0016272;prefoldin complex;0.00737091907343036!GO:0051098;regulation of binding;0.00744871300283243!GO:0007034;vacuolar transport;0.00756108498727787!GO:0006270;DNA replication initiation;0.0076689633339609!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00777326974453111!GO:0006595;polyamine metabolic process;0.00778746062717342!GO:0016408;C-acyltransferase activity;0.00778772516628859!GO:0006144;purine base metabolic process;0.00791484095905583!GO:0016197;endosome transport;0.00795288260579038!GO:0016584;nucleosome positioning;0.00795288260579038!GO:0008047;enzyme activator activity;0.00797191046850897!GO:0008270;zinc ion binding;0.00800030700614747!GO:0030176;integral to endoplasmic reticulum membrane;0.00800030700614747!GO:0000049;tRNA binding;0.00800030700614747!GO:0033116;ER-Golgi intermediate compartment membrane;0.00825710723765391!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00833185533252137!GO:0048522;positive regulation of cellular process;0.00833357380241872!GO:0000792;heterochromatin;0.0083502846948247!GO:0009889;regulation of biosynthetic process;0.00854127811058395!GO:0009451;RNA modification;0.00885528541071857!GO:0042770;DNA damage response, signal transduction;0.00891272867695414!GO:0006520;amino acid metabolic process;0.0089741079700192!GO:0018193;peptidyl-amino acid modification;0.00902360259185353!GO:0000118;histone deacetylase complex;0.00916842264638055!GO:0008139;nuclear localization sequence binding;0.00916842264638055!GO:0051789;response to protein stimulus;0.00916842264638055!GO:0006986;response to unfolded protein;0.00916842264638055!GO:0007021;tubulin folding;0.0092074203294167!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00933989855441755!GO:0007040;lysosome organization and biogenesis;0.00940027983802669!GO:0051223;regulation of protein transport;0.0094794313123516!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00956527699392655!GO:0000725;recombinational repair;0.00956527699392655!GO:0000724;double-strand break repair via homologous recombination;0.00956527699392655!GO:0050662;coenzyme binding;0.00970133599015102!GO:0009161;ribonucleoside monophosphate metabolic process;0.00973369050819605!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.00973369050819605!GO:0046983;protein dimerization activity;0.00978708325897029!GO:0044431;Golgi apparatus part;0.0098278901388858!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00999365110821842!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0103091975015192!GO:0006611;protein export from nucleus;0.0103247062513892!GO:0005663;DNA replication factor C complex;0.0106494347322311!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0109904669909936!GO:0008610;lipid biosynthetic process;0.0109904669909936!GO:0031123;RNA 3'-end processing;0.0110137808850682!GO:0000339;RNA cap binding;0.0112163844734771!GO:0006220;pyrimidine nucleotide metabolic process;0.0114932063792819!GO:0044438;microbody part;0.0115017260007326!GO:0044439;peroxisomal part;0.0115017260007326!GO:0005765;lysosomal membrane;0.0115453399851615!GO:0000059;protein import into nucleus, docking;0.01158836102661!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0116680408236933!GO:0005669;transcription factor TFIID complex;0.0118367701380425!GO:0046128;purine ribonucleoside metabolic process;0.0121533307415202!GO:0042278;purine nucleoside metabolic process;0.0121533307415202!GO:0032200;telomere organization and biogenesis;0.0121770196746321!GO:0000723;telomere maintenance;0.0121770196746321!GO:0006275;regulation of DNA replication;0.0122002154668299!GO:0006740;NADPH regeneration;0.0124410194105594!GO:0006098;pentose-phosphate shunt;0.0124410194105594!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0124482705438794!GO:0043241;protein complex disassembly;0.0127115376714235!GO:0005832;chaperonin-containing T-complex;0.0127142199156139!GO:0043601;nuclear replisome;0.0130878829670423!GO:0030894;replisome;0.0130878829670423!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0131977265207538!GO:0006376;mRNA splice site selection;0.0135203110196087!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0135203110196087!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0139540290339574!GO:0004674;protein serine/threonine kinase activity;0.0142136132930856!GO:0030663;COPI coated vesicle membrane;0.0143366360699091!GO:0030126;COPI vesicle coat;0.0143366360699091!GO:0030118;clathrin coat;0.0147290502241119!GO:0008180;signalosome;0.0149499901101443!GO:0000819;sister chromatid segregation;0.0152036156013382!GO:0031903;microbody membrane;0.0152036156013382!GO:0005778;peroxisomal membrane;0.0152036156013382!GO:0000726;non-recombinational repair;0.0152036156013382!GO:0006355;regulation of transcription, DNA-dependent;0.0152036156013382!GO:0003887;DNA-directed DNA polymerase activity;0.0152241363727232!GO:0004576;oligosaccharyl transferase activity;0.0152824654276521!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0154932592874843!GO:0051920;peroxiredoxin activity;0.0154992249241865!GO:0044262;cellular carbohydrate metabolic process;0.0155000022213021!GO:0044454;nuclear chromosome part;0.0162038612261302!GO:0007033;vacuole organization and biogenesis;0.0162111181700056!GO:0016044;membrane organization and biogenesis;0.0164047747331101!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0166542118797047!GO:0006607;NLS-bearing substrate import into nucleus;0.0170812694233007!GO:0042158;lipoprotein biosynthetic process;0.0170966435831158!GO:0000070;mitotic sister chromatid segregation;0.0173348085014714!GO:0009615;response to virus;0.0178794304319334!GO:0006458;'de novo' protein folding;0.0180417550411478!GO:0051084;'de novo' posttranslational protein folding;0.0180417550411478!GO:0008629;induction of apoptosis by intracellular signals;0.0182679703914347!GO:0008538;proteasome activator activity;0.0186138712831305!GO:0004540;ribonuclease activity;0.0191609339868047!GO:0006891;intra-Golgi vesicle-mediated transport;0.0193604328131692!GO:0046966;thyroid hormone receptor binding;0.0195308768263436!GO:0006643;membrane lipid metabolic process;0.019566633290132!GO:0051101;regulation of DNA binding;0.0195699354278822!GO:0045045;secretory pathway;0.0197330956730618!GO:0006378;mRNA polyadenylation;0.0197714637847896!GO:0008250;oligosaccharyl transferase complex;0.0205091519840353!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0210148092648794!GO:0043624;cellular protein complex disassembly;0.02111522346919!GO:0000077;DNA damage checkpoint;0.0211990563770423!GO:0009119;ribonucleoside metabolic process;0.0212766632731527!GO:0019206;nucleoside kinase activity;0.0219250057726578!GO:0008624;induction of apoptosis by extracellular signals;0.0225423495887621!GO:0008408;3'-5' exonuclease activity;0.0227560362695099!GO:0051053;negative regulation of DNA metabolic process;0.023033992376543!GO:0033367;protein localization in mast cell secretory granule;0.023033992376543!GO:0033365;protein localization in organelle;0.023033992376543!GO:0033371;T cell secretory granule organization and biogenesis;0.023033992376543!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.023033992376543!GO:0033375;protease localization in T cell secretory granule;0.023033992376543!GO:0042629;mast cell granule;0.023033992376543!GO:0033377;maintenance of protein localization in T cell secretory granule;0.023033992376543!GO:0033364;mast cell secretory granule organization and biogenesis;0.023033992376543!GO:0033380;granzyme B localization in T cell secretory granule;0.023033992376543!GO:0033379;maintenance of protease localization in T cell secretory granule;0.023033992376543!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.023033992376543!GO:0033368;protease localization in mast cell secretory granule;0.023033992376543!GO:0033366;protein localization in secretory granule;0.023033992376543!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.023033992376543!GO:0033374;protein localization in T cell secretory granule;0.023033992376543!GO:0043022;ribosome binding;0.023033992376543!GO:0000119;mediator complex;0.0239407246079748!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0241242918540542!GO:0000209;protein polyubiquitination;0.0245465145046841!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0245785773270774!GO:0051235;maintenance of localization;0.0249861773185495!GO:0006672;ceramide metabolic process;0.0252342455631356!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0252706286138869!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0254879472269114!GO:0010257;NADH dehydrogenase complex assembly;0.0254879472269114!GO:0033108;mitochondrial respiratory chain complex assembly;0.0254879472269114!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0256422751509704!GO:0045039;protein import into mitochondrial inner membrane;0.0256422751509704!GO:0007264;small GTPase mediated signal transduction;0.0258917064280547!GO:0046914;transition metal ion binding;0.0261100428586755!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0261100428586755!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0261100428586755!GO:0009126;purine nucleoside monophosphate metabolic process;0.0261100428586755!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0261100428586755!GO:0032940;secretion by cell;0.0264777738579209!GO:0004300;enoyl-CoA hydratase activity;0.0269923278183207!GO:0004177;aminopeptidase activity;0.0270513091465746!GO:0006406;mRNA export from nucleus;0.0272499874252273!GO:0043284;biopolymer biosynthetic process;0.027463304022236!GO:0030518;steroid hormone receptor signaling pathway;0.0274783210392005!GO:0000152;nuclear ubiquitin ligase complex;0.0274804626901288!GO:0033157;regulation of intracellular protein transport;0.0275311054483559!GO:0042306;regulation of protein import into nucleus;0.0275311054483559!GO:0035258;steroid hormone receptor binding;0.0278580150973859!GO:0006360;transcription from RNA polymerase I promoter;0.0280822067859744!GO:0045185;maintenance of protein localization;0.0280934527131785!GO:0009303;rRNA transcription;0.0281517771245463!GO:0005869;dynactin complex;0.0282313123033497!GO:0030041;actin filament polymerization;0.0291472648738828!GO:0031970;organelle envelope lumen;0.029185484932964!GO:0004532;exoribonuclease activity;0.0292508350830599!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0292508350830599!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0295285111100443!GO:0005784;translocon complex;0.0295350954421758!GO:0018196;peptidyl-asparagine modification;0.0295350954421758!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0295350954421758!GO:0048471;perinuclear region of cytoplasm;0.0301019789814222!GO:0016407;acetyltransferase activity;0.0304126747555402!GO:0006007;glucose catabolic process;0.0309915033642736!GO:0008097;5S rRNA binding;0.0310106755607643!GO:0022415;viral reproductive process;0.0310835968925592!GO:0006779;porphyrin biosynthetic process;0.0311861427613203!GO:0033014;tetrapyrrole biosynthetic process;0.0311861427613203!GO:0008637;apoptotic mitochondrial changes;0.0315569768606345!GO:0000097;sulfur amino acid biosynthetic process;0.0321381360830299!GO:0030658;transport vesicle membrane;0.0325114390474895!GO:0004448;isocitrate dehydrogenase activity;0.0328291485453932!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0330024514447411!GO:0003746;translation elongation factor activity;0.0331447447139408!GO:0045892;negative regulation of transcription, DNA-dependent;0.0335082630652735!GO:0043281;regulation of caspase activity;0.0338182778485333!GO:0001726;ruffle;0.0342073916504489!GO:0030137;COPI-coated vesicle;0.0346097381671085!GO:0006778;porphyrin metabolic process;0.0348946101373121!GO:0033013;tetrapyrrole metabolic process;0.0348946101373121!GO:0046519;sphingoid metabolic process;0.0351109177264146!GO:0006730;one-carbon compound metabolic process;0.0352462043243247!GO:0033170;DNA-protein loading ATPase activity;0.0355165336146273!GO:0003689;DNA clamp loader activity;0.0355165336146273!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0355397361149209!GO:0008276;protein methyltransferase activity;0.0355611719866483!GO:0009396;folic acid and derivative biosynthetic process;0.0356859074602421!GO:0030508;thiol-disulfide exchange intermediate activity;0.0364566302889393!GO:0005095;GTPase inhibitor activity;0.0370600366139179!GO:0008022;protein C-terminus binding;0.0370600366139179!GO:0006266;DNA ligation;0.0372399427103059!GO:0031647;regulation of protein stability;0.037303220123406!GO:0003923;GPI-anchor transamidase activity;0.0378996828428316!GO:0016255;attachment of GPI anchor to protein;0.0378996828428316!GO:0042765;GPI-anchor transamidase complex;0.0378996828428316!GO:0004096;catalase activity;0.037904742684615!GO:0043130;ubiquitin binding;0.0380066041554024!GO:0032182;small conjugating protein binding;0.0380066041554024!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0385473040691647!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0385473040691647!GO:0044450;microtubule organizing center part;0.0397694771572509!GO:0031577;spindle checkpoint;0.0398843835152572!GO:0009081;branched chain family amino acid metabolic process;0.0398843835152572!GO:0048037;cofactor binding;0.0404838276883247!GO:0005777;peroxisome;0.0409205504074028!GO:0042579;microbody;0.0409205504074028!GO:0009262;deoxyribonucleotide metabolic process;0.0409205504074028!GO:0051085;chaperone cofactor-dependent protein folding;0.0414335221255202!GO:0051336;regulation of hydrolase activity;0.0417964263976795!GO:0032507;maintenance of cellular protein localization;0.0419608574443095!GO:0007259;JAK-STAT cascade;0.0419608574443095!GO:0004722;protein serine/threonine phosphatase activity;0.0421196234206903!GO:0006644;phospholipid metabolic process;0.0427554585646656!GO:0030433;ER-associated protein catabolic process;0.0436611737648987!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0436611737648987!GO:0022406;membrane docking;0.0441296218289142!GO:0048278;vesicle docking;0.0441296218289142!GO:0000790;nuclear chromatin;0.0446794196240629!GO:0008537;proteasome activator complex;0.0460041767714408!GO:0030132;clathrin coat of coated pit;0.046617293554697!GO:0006118;electron transport;0.0485057149185632!GO:0006635;fatty acid beta-oxidation;0.0487155572822777!GO:0005092;GDP-dissociation inhibitor activity;0.0487702705980649!GO:0006400;tRNA modification;0.0492984691034174!GO:0035267;NuA4 histone acetyltransferase complex;0.0493185254133605!GO:0016788;hydrolase activity, acting on ester bonds;0.049889291395755 | |||
|sample_id=10789 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=E2F1..5:1.72644628951;ELF1,2,4:1.5470790401;MYB:1.47095167978;STAT1,3:1.46768205428;YY1:1.43837295917;ARID5B:1.42256706282;SPIB:1.33171578644;NANOG:1.26017295839;RUNX1..3:1.23696727344;NFY{A,B,C}:1.19768065865;GATA6:1.18223155653;FOXP3:1.17785967897;NANOG{mouse}:1.16038899618;DMAP1_NCOR{1,2}_SMARC:1.10989931382;TLX2:1.1019163969;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.05893912812;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.03485394892;ALX1:0.976737334392;PBX1:0.926528801323;SPI1:0.899294291914;FOXA2:0.846911461129;NR5A1,2:0.841498517118;ETS1,2:0.822974328971;POU2F1..3:0.790226726768;ZNF143:0.773457099386;ELK1,4_GABP{A,B1}:0.728802522007;HBP1_HMGB_SSRP1_UBTF:0.670158188981;NKX2-3_NKX2-5:0.516068899093;HAND1,2:0.513670726429;TGIF1:0.49665591752;FOX{I1,J2}:0.492531958703;IKZF2:0.438985237887;CDX1,2,4:0.402976955284;NRF1:0.377399473027;NR6A1:0.352033984642;NKX2-2,8:0.345252039918;MYOD1:0.292236199357;CUX2:0.285006449967;RORA:0.280048959313;SREBF1,2:0.279878368203;POU5F1:0.240869680139;OCT4_SOX2{dimer}:0.234006669533;ESRRA:0.228382959418;POU3F1..4:0.214174337437;FOXQ1:0.186644990752;SOX5:0.186547521162;ZNF148:0.173071220678;RXR{A,B,G}:0.163982834436;SOX{8,9,10}:0.16232864047;PAX4:0.138989894156;GFI1:0.13868842773;PAX8:0.128952558283;PAX5:0.12772601478;VSX1,2:0.0800736851521;BREu{core}:0.0785892427799;IRF1,2:0.0719360226605;CRX:0.0715026850251;HOX{A6,A7,B6,B7}:0.041614577457;PAX6:0.0342217863721;IRF7:0.0291442118478;BPTF:0.0253762323494;NFKB1_REL_RELA:0.0154440582777;HMGA1,2:0.0124336477448;RXRA_VDR{dimer}:0.00308859924423;PAX2:-0.00264120319811;DBP:-0.0320471280627;STAT5{A,B}:-0.033496468357;EN1,2:-0.0337891851719;PPARG:-0.0371878309052;GCM1,2:-0.038313564206;LHX3,4:-0.0396695140688;T:-0.0645928702216;HOXA9_MEIS1:-0.0894966814365;PAX3,7:-0.0901712460779;ZEB1:-0.10646723143;RFX2..5_RFXANK_RFXAP:-0.112975915721;TEF:-0.114115259049;ATF5_CREB3:-0.144960540025;ESR1:-0.149761916279;NFIL3:-0.162354957005;ZNF238:-0.166934924656;SOX17:-0.168925845447;GZF1:-0.173052908445;MEF2{A,B,C,D}:-0.180613416237;ONECUT1,2:-0.190028555843;HNF4A_NR2F1,2:-0.191367672017;NFE2:-0.208548526316;HNF1A:-0.211669633408;TFDP1:-0.213805623091;SNAI1..3:-0.247260347097;FOXM1:-0.256751275432;HIF1A:-0.260585364118;HES1:-0.276387613836;NFIX:-0.279078565008;AR:-0.28143110824;FOX{F1,F2,J1}:-0.281995187703;CEBPA,B_DDIT3:-0.291139061319;FOSL2:-0.304852722251;NFATC1..3:-0.308317920795;HSF1,2:-0.311740937257;STAT2,4,6:-0.321795593153;FOXN1:-0.343316797934;LEF1_TCF7_TCF7L1,2:-0.378331197439;CREB1:-0.39053311463;REST:-0.396796997642;PDX1:-0.399098889781;MYBL2:-0.403478731261;RBPJ:-0.407729555558;TFAP4:-0.409637328066;PRRX1,2:-0.418868062307;TBP:-0.426775593027;SMAD1..7,9:-0.430269784105;FOX{D1,D2}:-0.444173549516;AHR_ARNT_ARNT2:-0.446487768401;TAL1_TCF{3,4,12}:-0.450064876594;BACH2:-0.459338541472;NKX3-1:-0.471146267709;SOX2:-0.473806754931;PRDM1:-0.480697106089;FOS_FOS{B,L1}_JUN{B,D}:-0.490926062805;SPZ1:-0.497828648485;RFX1:-0.498449313254;PITX1..3:-0.504260128354;NFE2L1:-0.505787995908;HOX{A4,D4}:-0.51727768758;HLF:-0.529690959479;XBP1:-0.543738300324;ATF4:-0.58412018155;EP300:-0.593720499743;SRF:-0.606897843528;bHLH_family:-0.611679872431;ZNF384:-0.61824663316;FOXP1:-0.620594448601;GTF2I:-0.631047485936;ZBTB16:-0.640697773934;NFE2L2:-0.644346474468;KLF4:-0.676723053528;HIC1:-0.686178102346;EBF1:-0.700381602214;TOPORS:-0.712987282028;MYFfamily:-0.716596710827;MAFB:-0.737893310313;NR1H4:-0.752747366715;ATF2:-0.759398803672;NHLH1,2:-0.789101702813;FOXD3:-0.789660306623;FOXO1,3,4:-0.818725906722;XCPE1{core}:-0.842951666044;TP53:-0.864908304815;LMO2:-0.866885032712;POU1F1:-0.871354207915;ZNF423:-0.877893656527;ZBTB6:-0.903755155498;SP1:-0.905832520044;GLI1..3:-0.913034204285;TFAP2B:-0.915092188593;NKX6-1,2:-0.918697259237;GATA4:-0.936071372739;HOX{A5,B5}:-0.939903471493;UFEwm:-0.940486651641;IKZF1:-0.948392102963;MAZ:-0.949323168039;NKX2-1,4:-0.98026781202;MZF1:-0.984810504822;EVI1:-0.996099012323;HMX1:-1.00043956642;TFAP2{A,C}:-1.00084096764;NKX3-2:-1.00128308488;CDC5L:-1.00504880086;PAX1,9:-1.06953518126;GTF2A1,2:-1.07900962589;GFI1B:-1.08834867408;MTE{core}:-1.09454653703;ZFP161:-1.10131550727;JUN:-1.11088676589;ZIC1..3:-1.11453401226;TLX1..3_NFIC{dimer}:-1.13103203557;TEAD1:-1.16761279955;AIRE:-1.19282633133;EGR1..3:-1.2004231903;MTF1:-1.20899467838;RREB1:-1.29930551115;MED-1{core}:-1.36477340008;TBX4,5:-1.37378231996;POU6F1:-1.39147705606;ALX4:-1.4152752045;ATF6:-1.4166443021;PATZ1:-1.42955327316;NR3C1:-1.52428097105;ADNP_IRX_SIX_ZHX:-1.62059277327;TFCP2:-1.63480449481;FOXL1:-2.21198275551 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10789-110H6;search_select_hide=table117:FF:10789-110H6 | |||
}} | }} |
Latest revision as of 15:04, 3 June 2020
Name: | acute myeloid leukemia (FAB M0) cell line:Kasumi-3 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13241 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13241
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13241
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.37 |
10 | 10 | 0.032 |
100 | 100 | 0.993 |
101 | 101 | 0.613 |
102 | 102 | 0.393 |
103 | 103 | 0.0127 |
104 | 104 | 0.467 |
105 | 105 | 0.518 |
106 | 106 | 0.786 |
107 | 107 | 0.304 |
108 | 108 | 0.253 |
109 | 109 | 0.0322 |
11 | 11 | 0.0374 |
110 | 110 | 0.217 |
111 | 111 | 0.617 |
112 | 112 | 0.351 |
113 | 113 | 0.674 |
114 | 114 | 0.31 |
115 | 115 | 0.457 |
116 | 116 | 0.847 |
117 | 117 | 0.0272 |
118 | 118 | 0.0216 |
119 | 119 | 0.653 |
12 | 12 | 0.463 |
120 | 120 | 0.406 |
121 | 121 | 0.647 |
122 | 122 | 0.361 |
123 | 123 | 0.524 |
124 | 124 | 0.0583 |
125 | 125 | 0.123 |
126 | 126 | 0.115 |
127 | 127 | 0.177 |
128 | 128 | 0.815 |
129 | 129 | 0.216 |
13 | 13 | 0.0014 |
130 | 130 | 0.0524 |
131 | 131 | 0.22 |
132 | 132 | 0.468 |
133 | 133 | 0.731 |
134 | 134 | 0.833 |
135 | 135 | 0.468 |
136 | 136 | 0.119 |
137 | 137 | 0.153 |
138 | 138 | 0.796 |
139 | 139 | 0.944 |
14 | 14 | 0.98 |
140 | 140 | 0.416 |
141 | 141 | 0.624 |
142 | 142 | 0.547 |
143 | 143 | 0.414 |
144 | 144 | 0.246 |
145 | 145 | 0.858 |
146 | 146 | 0.51 |
147 | 147 | 0.0112 |
148 | 148 | 0.845 |
149 | 149 | 0.886 |
15 | 15 | 0.105 |
150 | 150 | 0.339 |
151 | 151 | 0.878 |
152 | 152 | 0.81 |
153 | 153 | 0.221 |
154 | 154 | 0.544 |
155 | 155 | 0.257 |
156 | 156 | 0.361 |
157 | 157 | 0.358 |
158 | 158 | 0.827 |
159 | 159 | 0.487 |
16 | 16 | 0.913 |
160 | 160 | 0.396 |
161 | 161 | 0.063 |
162 | 162 | 0.263 |
163 | 163 | 0.534 |
164 | 164 | 0.544 |
165 | 165 | 0.263 |
166 | 166 | 0.205 |
167 | 167 | 0.447 |
168 | 168 | 0.755 |
169 | 169 | 0.406 |
17 | 17 | 0.973 |
18 | 18 | 0.361 |
19 | 19 | 0.871 |
2 | 2 | 0.797 |
20 | 20 | 0.54 |
21 | 21 | 0.794 |
22 | 22 | 0.419 |
23 | 23 | 0.00686 |
24 | 24 | 0.0207 |
25 | 25 | 0.0242 |
26 | 26 | 0.152 |
27 | 27 | 0.25 |
28 | 28 | 0.97 |
29 | 29 | 0.0573 |
3 | 3 | 0.0201 |
30 | 30 | 0.309 |
31 | 31 | 0.33 |
32 | 32 | 0.0288 |
33 | 33 | 0.0939 |
34 | 34 | 0.528 |
35 | 35 | 0.29 |
36 | 36 | 0.0446 |
37 | 37 | 0.115 |
38 | 38 | 0.458 |
39 | 39 | 0.225 |
4 | 4 | 0.0966 |
40 | 40 | 0.0273 |
41 | 41 | 0.718 |
42 | 42 | 0.0581 |
43 | 43 | 0.452 |
44 | 44 | 0.611 |
45 | 45 | 0.921 |
46 | 46 | 0.17 |
47 | 47 | 0.0153 |
48 | 48 | 0.0202 |
49 | 49 | 0.322 |
5 | 5 | 0.831 |
50 | 50 | 0.897 |
51 | 51 | 0.729 |
52 | 52 | 0.344 |
53 | 53 | 0.305 |
54 | 54 | 0.538 |
55 | 55 | 0.813 |
56 | 56 | 0.828 |
57 | 57 | 0.538 |
58 | 58 | 0.188 |
59 | 59 | 0.229 |
6 | 6 | 0.816 |
60 | 60 | 0.606 |
61 | 61 | 0.136 |
62 | 62 | 0.228 |
63 | 63 | 0.953 |
64 | 64 | 0.191 |
65 | 65 | 0.47 |
66 | 66 | 0.00443 |
67 | 67 | 0.913 |
68 | 68 | 0.526 |
69 | 69 | 0.755 |
7 | 7 | 0.00176 |
70 | 70 | 0.215 |
71 | 71 | 0.0142 |
72 | 72 | 0.465 |
73 | 73 | 0.276 |
74 | 74 | 0.704 |
75 | 75 | 0.0112 |
76 | 76 | 0.276 |
77 | 77 | 0.686 |
78 | 78 | 0.00401 |
79 | 79 | 0.0233 |
8 | 8 | 0.264 |
80 | 80 | 0.358 |
81 | 81 | 0.974 |
82 | 82 | 0.883 |
83 | 83 | 0.0358 |
84 | 84 | 0.8 |
85 | 85 | 0.399 |
86 | 86 | 0.497 |
87 | 87 | 0.0259 |
88 | 88 | 0.324 |
89 | 89 | 0.81 |
9 | 9 | 0.141 |
90 | 90 | 0.283 |
91 | 91 | 0.863 |
92 | 92 | 0.0791 |
93 | 93 | 0.178 |
94 | 94 | 0.763 |
95 | 95 | 7.02915e-5 |
96 | 96 | 0.608 |
97 | 97 | 0.56 |
98 | 98 | 0.39 |
99 | 99 | 0.384 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13241
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0101883 acute myeloid leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0101883 (acute myeloid leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)