FF:10848-111F2: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005921 | ||
| | |accession_numbers=CAGE;DRX007948;DRR008820;DRZ000245;DRZ001630;DRZ011595;DRZ012980 | ||
| | |ancestors_in_anatomy_facet=UBERON:0002384,UBERON:0000479,UBERON:0000061,UBERON:0000465,UBERON:0001062 | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0000066,CL:0002371,CL:0000076,CL:0000213,CL:0000215,CL:0000255,CL:0000057,CL:0000077 | ||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:1115 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100453,FF:0100400,FF:0100460,FF:0102424,FF:0103764 | |||
|comment= | |||
| | |created_by= | ||
|creation_date= | |||
| | |data_phase=2 | ||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr6:28321909..28321965,-!p3@ZNF323!1.56!35.65!ZNF323;;chr11:61520075..61520136,+!p1@C11orf9!1.55!71.29!C11orf9;;chr17:7493405..7493419,-!p1@SOX15!1.45!27.37!SOX15;;chr15:67418047..67418093,+!p4@SMAD3!1.39!29.40!SMAD3;;chr6:10415276..10415341,-!p2@TFAP2A!1.32!24.33!TFAP2A;;chr15:67418119..67418162,+!p5@SMAD3!1.27!19.43!SMAD3;;chr6:10412392..10412409,-!p4@TFAP2A!1.25!19.09!TFAP2A;;chr17:7492684..7492778,-!p2@SOX15!1.22!32.77!SOX15;;chr6:28321971..28321995,-!p1@ZNF323!1.22!15.71!ZNF323;;chr15:83953397..83953425,-!p1@BNC1!1.17!15.71!BNC1;;chr11:31832658..31832681,-!p1@PAX6!1.16!13.52!PAX6;;chr6:10412600..10412637,-!p1@TFAP2A!1.13!20.61!TFAP2A;;chr6:19837592..19837621,+!p1@ID4!1.08!67.24!ID4;;chr5:134369905..134369972,-!p1@PITX1!1.07!16.73!PITX1;;chr11:615570..615721,-!p2@IRF7!1.03!19.43!IRF7;;chr6:85473156..85473210,-!p2@TBX18!1.03!11.99!TBX18;;chr6:126240380..126240430,+!p2@NCOA7!1.02!24.83!NCOA7;;chr15:67418177..67418204,+!p9@SMAD3!0.99!8.79!SMAD3;;chr2:19558373..19558392,-!p1@OSR1!0.97!23.48!OSR1;;chr5:2751762..2751784,-!p1@IRX2!0.97!8.28!IRX2;;chr7:149470540..149470596,-!p2@ZNF467!0.96!10.81!ZNF467;;chr8:106330656..106330684,+!p1@ZFPM2!0.94!20.61!ZFPM2;;chr6:126240356..126240379,+!p7@NCOA7!0.94!9.46!NCOA7;;chr7:26191809..26191890,+!p1@NFE2L3!0.89!35.48!NFE2L3;;chr7:35293685..35293718,-!p1@TBX20!0.87!6.42!TBX20;;chr19:13134772..13134822,+!p2@NFIX!0.85!9.29!NFIX;;chrY:21906594..21906622,-!p1@KDM5D!0.84!5.91!KDM5D;;chr3:141747459..141747475,-!p1@TFDP2!0.83!51.53!TFDP2;;chr8:37963466..37963506,+!p3@ASH2L!0.83!7.26!ASH2L;;chr11:32457075..32457095,-!p1@WT1!0.83!5.74!WT1;;chr18:6414884..6414942,-!p1@L3MBTL4!0.82!7.26!L3MBTL4;;chr15:37390374..37390422,-!p9@MEIS2!0.81!6.93!MEIS2;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!0.81!5.41!SEBOX;;chr1:44513995..44514031,+!p1@KLF17!0.81!5.41!KLF17;;chr17:41277372..41277418,-!p1@BRCA1!0.80!20.78!BRCA1;;chr18:19749541..19749557,+!p1@GATA6!0.80!17.91!GATA6;;chr3:128206762..128206781,-!p2@GATA2!0.79!35.31!GATA2;;chr7:149470641..149470694,-!p1@ZNF467!0.79!25.51!ZNF467;;chr8:37963407..37963454,+!p2@ASH2L!0.79!16.39!ASH2L;;chr15:37390482..37390572,-!p7@MEIS2!0.79!7.26!MEIS2;;chr5:3595934..3595957,+!p2@IRX1!0.78!5.07!IRX1;;chrY:2803415..2803468,+!p1@ZFY!0.78!5.07!ZFY;;chr2:46524897..46524911,+!p2@EPAS1!0.77!14.70!EPAS1;;chr14:24630902..24630948,+!p2@IRF9!0.77!6.08!IRF9;;chr5:92918919..92918942,+!p1@NR2F1!0.76!23.48!NR2F1;;chr11:31832610..31832639,-!p5@PAX6!0.76!4.73!PAX6;;chr11:65667884..65667895,-!p2@FOSL1!0.75!19.60!FOSL1;;chr15:37392616..37392638,-!p2@MEIS2!0.75!15.88!MEIS2;;chr3:114343768..114343822,-!p1@ZBTB20!0.74!21.46!ZBTB20;;chr11:120107344..120107351,+!p1@POU2F3!0.74!5.58!POU2F3;;chr12:104531823..104531849,-!p5@NFYB!0.72!9.46!NFYB;;chr1:158985493..158985535,+!p4@IFI16!0.72!6.76!IFI16;;chr8:106330696..106330719,+!p2@ZFPM2!0.72!5.58!ZFPM2;;chrX:30327504..30327509,-!p1@NR0B1!0.72!4.22!NR0B1;;chr15:67418099..67418118,+!p16@SMAD3!0.72!4.22!SMAD3;;chr11:615942..615957,-!p1@IRF7!0.71!44.26!IRF7;;chr5:92919100..92919135,+!p3@NR2F1!0.70!5.07!NR2F1;;chr6:28321827..28321856,-!p5@ZNF323!0.70!4.05!ZNF323;;chr15:96869255..96869291,+!p6@NR2F2!0.69!7.60!NR2F2;;chr15:96869292..96869320,+!p15@NR2F2!0.69!5.91!NR2F2;;chr7:101917407..101917443,+!p3@CUX1!0.69!3.89!CUX1;;chr20:30193083..30193098,+!p1@ID1!0.67!348.19!ID1;;chr3:114343826..114343869,-!p4@ZBTB20!0.67!7.94!ZBTB20;;chr5:3595977..3595999,+!p1@IRX1!0.67!3.72!IRX1;;chr7:64023410..64023428,-!p2@ZNF680!0.66!6.08!ZNF680;;chr8:10588010..10588030,-!p1@SOX7!0.66!3.55!SOX7;;chr4:299227..299272,-!p1@ZNF732!0.66!3.55!ZNF732;;chr12:2986206..2986258,-!p2@FOXM1!0.65!24.50!FOXM1;;chr15:37392724..37392757,-!p1@MEIS2!0.65!18.25!MEIS2;;chr12:2986275..2986363,-!p1@FOXM1!0.64!40.04!FOXM1;;chr20:61051039..61051057,-!p1@GATA5!0.64!3.38!GATA5;;chr7:19157043..19157088,-!p2@TWIST1!0.62!9.12!TWIST1;;chr16:79633894..79633954,-!p3@MAF!0.62!6.76!MAF;;chr19:13134457..13134462,+!p5@NFIX!0.62!6.25!NFIX;;chr2:231084639..231084654,-!p2@SP110!0.62!5.74!SP110;;chr1:158985469..158985489,+!p7@IFI16!0.62!3.89!IFI16;;chr9:130966497..130966541,-!p4@CIZ1!0.62!3.21!CIZ1;;chr11:65667846..65667868,-!p1@FOSL1!0.61!98.32!FOSL1;;chr5:92918894..92918912,+!p2@NR2F1!0.61!11.66!NR2F1;;chr12:80084167..80084197,-!p5@PAWR!0.61!8.11!PAWR;;chr6:85474299..85474324,-!p1@TBX18!0.61!6.08!TBX18;;chr10:35415951..35415975,+!p8@CREM!0.61!4.56!CREM;;chr15:37392576..37392589,-!p12@MEIS2!0.61!3.89!MEIS2;;chr15:83953373..83953386,-!p2@BNC1!0.61!3.04!BNC1;;chr16:85932760..85932775,+!p1@IRF8!0.61!3.04!IRF8;;chr3:128207349..128207386,-!p3@GATA2!0.61!3.04!GATA2;;chr12:66218836..66218888,+!p1@HMGA2!0.60!33.62!HMGA2;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.60!16.22!TAL1;;chr17:46655730..46655791,-!p1@HOXB4!0.60!8.45!HOXB4;;chr16:8962544..8962584,-!p2@CARHSP1!0.60!7.77!CARHSP1;;chr15:37392094..37392116,-!p6@MEIS2!0.60!3.89!MEIS2;;chr11:65687362..65687436,+!p3@DRAP1!0.59!15.54!DRAP1;;chr16:8962202..8962222,-!p3@CARHSP1!0.59!5.74!CARHSP1;;chr11:32457103..32457123,-!p3@WT1!0.59!2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;chr19:56110859..56110917,-!p1@FIZ1!0.14!7.43!FIZ1;;chr19:21264991..21265026,+!p1@ZNF714!0.14!7.43!ZNF714;;chr19:53898380..53898422,+!p1@ZNF765!0.14!6.93!ZNF765;;chr6:28317685..28317761,+!p1@ZKSCAN3!0.14!5.58!ZKSCAN3;;chr6:28220023..28220053,-!p1@ZKSCAN4!0.14!4.73!ZKSCAN4;;chr1:8585945..8586056,-!p3@RERE!0.14!3.38!RERE;;chr1:211433275..211433335,+!p2@RCOR3!0.14!3.04!RCOR3;;chr2:148778570..148778589,+!p4@MBD5!0.14!3.04!MBD5;;chr12:6798056..6798102,-!p3@ZNF384!0.14!2.87!ZNF384;;chr4:1873155..1873185,+!p3@WHSC1!0.14!2.70!WHSC1;;chr1:8483756..8483809,-!p5@RERE!0.14!2.70!RERE;;chr2:172967621..172967637,-!p1@DLX2!0.14!2.53!DLX2;;chr19:20150301..20150321,-!p1@ZNF682!0.14!2.37!ZNF682;;chr19:46271505..46271575,-!p2@SIX5!0.14!2.37!SIX5;;chr12:133758115..133758138,+!p3@ZNF268!0.14!2.20!ZNF268;;chr1:211432887..211432903,+!p4@RCOR3!0.14!2.03!RCOR3;;chr19:52839515..52839572,+!p1@ZNF610!0.14!1.86!ZNF610;;chr10:77161133..77161176,-!p3@ZNF503!0.14!1.86!ZNF503;;chr6:41514005..41514026,+!p3@FOXP4!0.14!1.86!FOXP4;;chr1:151253991..151254031,+!p2@ZNF687!0.14!1.52!ZNF687;;chr7:86781858..86781879,+!p3@DMTF1!0.14!1.18!DMTF1;;chr10:21823381..21823399,+!p4@MLLT10!0.14!1.18!MLLT10;;chr4:87968203..87968221,+!p11@AFF1!0.14!1.18!AFF1;;chr4:87928105..87928126,+!p13@AFF1!0.14!1.01!AFF1;;chr12:125002739..125002756,-!p6@NCOR2!0.14!1.01!NCOR2;;chr19:57019215..57019250,+!p1@ZNF471!0.14!1.01!ZNF471;;chr15:57210795..57210809,+!p8@TCF12!0.14!1.01!TCF12;;chr19:3366625..3366629,+!p4@NFIC!0.14!1.01!NFIC;;chr16:30546275..30546297,-!p2@ZNF747!0.14!0.84!ZNF747;;chr17:46621101..46621143,-!p7@HOXB2!0.14!0.84!HOXB2;;chr19:11750566..11750627,+!p1@ZNF833P!0.14!0.84!ZNF833P;;chr16:86544113..86544145,+!p1@FOXF1!0.14!0.68!FOXF1;;chr16:69419724..69419735,-!p4@TERF2!0.14!0.51!TERF2;;chr18:3448314..3448333,+!p18@TGIF1!0.14!0.51!TGIF1;;chr2:24930425..24930435,+!p4@NCOA1!0.14!0.51!NCOA1;;chr6:134273586..134273611,+!p5@TBPL1!0.14!0.51!TBPL1;;chr19:52772811..52772817,+!p3@ZNF766!0.14!0.51!ZNF766;;chrX:101187036..101187056,-!p2@ZMAT1!0.14!0.51!ZMAT1;;chr6:34204642..34204664,+!p2@HMGA1!0.13!163.87!HMGA1;;chr14:69259772..69259790,-!p1@ZFP36L1!0.13!126.20!ZFP36L1;;chr12:56753869..56753930,-!p1@STAT2!0.13!53.22!STAT2;;chr10:135122380..135122458,+!p1@ZNF511!0.13!36.83!ZNF511;;chr7:108210048..108210169,-!p1@THAP5,p2@PNPLA8!0.13!36.49!THAP5;;chr16:30798492..30798535,-!p1@ZNF629!0.13!18.58!ZNF629;;chr2:75937994..75938054,-!p1@GCFC2!0.13!16.73!GCFC2;;chr19:35168567..35168620,+!p1@ZNF302!0.13!13.52!ZNF302;;chr1:246729544..246729572,-!p1@TFB2M!0.13!11.32!TFB2M;;chr19:52490043..52490113,-!p1@ZNF350!0.13!8.95!ZNF350;;chr16:89284104..89284150,+!p1@ZNF778!0.13!7.94!ZNF778;;chr17:17740330..17740349,-!p3@SREBF1!0.13!7.43!SREBF1;;chr1:161736072..161736093,+!p2@ATF6!0.13!4.90!ATF6;;chr6:20403916..20403965,+!p3@E2F3!0.13!4.73!E2F3;;chr15:77713025..77713081,+!p2@HMG20A!0.13!4.56!HMG20A;;chr1:43148792..43148849,+!p2@YBX1!0.13!3.89!YBX1;;chrX:46404811..46404869,-!p1@ZNF674!0.13!3.72!ZNF674;;chr2:217277480..217277505,+!p2@SMARCAL1!0.13!3.38!SMARCAL1;;chr9:137217986..137218049,+!p3@RXRA!0.13!2.70!RXRA;;chr3:44754126..44754171,+!p1@ZNF502!0.13!2.20!ZNF502;;chr4:56413032..56413056,-!p2@CLOCK!0.13!2.20!CLOCK;; 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|ffid_belonging_in_development=CL:0000134,CL:0000222 | |||
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| | |||
|fonse_cell_line=FF:0100400,FF:0100453,FF:0102424 | |fonse_cell_line=FF:0100400,FF:0100453,FF:0102424 | ||
|fonse_cell_line_closure=FF:0100400,FF:0100453,FF:0102424 | |fonse_cell_line_closure=FF:0100400,FF:0100453,FF:0102424 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H2452.CNhs13064.10848-111F2.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H2452.CNhs13064.10848-111F2.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H2452.CNhs13064.10848-111F2.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H2452.CNhs13064.10848-111F2.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/mesothelioma%2520cell%2520line%253aNCI-H2452.CNhs13064.10848-111F2.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10848-111F2 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0102424;;FF:0103764 | |||
|is_obsolete= | |||
|library_id=CNhs13064 | |||
|library_id_phase_based=2:CNhs13064 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10848 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10848 | |||
|name=mesothelioma cell line:NCI-H2452 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13064,LSID1000,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0.673641356777498,0,0,0,0,0,0.0638963197116508,0,-0.1320804316184,0.135528443612987,0,0,0,0,0,0,0,0,0,0,0.0677931267972615,0,0,-0.0855298835511661,0,0,0,0,0,0.028460849776319,0,0,0.132972030969282,0,0,0,0,0,0,0,0,0,0,1.25679436612607,0,-0.0814564468999647,0,0,0,0,0,0,0,0,0.250492863459378,0,0,0,0,0,0,0,-0.0291992344453436,0,0,0.12687072258494,0,0,0,0,0,0,0,0,0.0677931267972615,0,0,0,0,0.0677931267972615,0,0,0,0.0744949977165685,0.0338965633986308,0,0.0402777562551652,0,0,0,0.0353661098647633,0,0,0,-0.0897160340064403,0.262784432022126,0,0.178063486278075,0,0,-0.0302422244404449,0.102547036345246,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.155946894025074,0,0,0,-0.0561307831042739,-0.182445446721576,0,0,0.0178104476103019,0,0,0 | |||
|repeat_enrich_byname=0,0,0,0.126418746044377,-0.0302422244404449,0,0,0.178063486278075,0,0,0,0,0.0677931267972615,0.178063486278075,0,0,-0.069115389007489,0,0.493376555882551,-0.143515142523472,0,0,-0.115142868255222,0,0.0677931267972615,0,0,0.0677931267972615,0,0,0.0677931267972615,0,-0.0603267401553032,0,0.0173805752079466,0,0.0677931267972615,0.0677931267972615,0,0,-0.305472230898407,0,-0.00477127577263425,0.197584359670777,0,0.0466442801327162,0,0,0.037797560499982,0,-0.120879483793741,0.0436985777209592,0,-0.406020954801793,-0.04680465889238,0,0,0,-0.17210363194477,-0.314690524332345,0,0,0.119244385394267,-0.147453055162028,0,0,-0.323251454754373,0,0.200959671134037,-0.0993965653463445,0,0.0994968521682253,0,0,0,0,0,0.126418746044377,0,0.0677931267972615,0,0,0,0.0396124695993824,0.0744949977165685,0.0971059364208192,0.0677931267972615,0.178063486278075,0,-0.210391312168,0,0,-0.107357535208422,-0.142006161844479,-0.0075491431353033,0.148139883353776,0,-0.0781753772118763,-0.0354751264754367,-0.328281797574344,-0.132885592023736,0.191571721382612,0.11400326846436,0,-0.0757735859000066,-0.198334869981475,0.0350326580653762,0.0712666191990126,-0.0316996235202638,0.0374037188445415,-0.0122597801555107,0.126418746044377,0.0677931267972615,0.132613576123617,-0.158658813139633,0,0,-0.118762431610423,-0.00353719969073491,-0.141121851048315,-0.0821500935783812,-6.23399313468555e-05,-0.164000934195118,0.138530957821405,-0.0277771111156716,0,0.226702381995606,0,0,-0.0453369183118792,-0.0664172740937746,0.0319902910137323,-0.186166831397756,0,-0.357558715766604,0.235640726936839,0,-0.244994756132256,-0.0342332501430085,0.0677931267972615,0,0.0625827198501406,0,0,0.153152078026062,0,0,0.0858490264698004,-0.138008548634629,0.168628032839993,0,0.0133151322914158,-0.0189281718506975,0.165717004598332,0,-0.140256284337583,-0.0638195054488879,0,-0.224840677798974,0,0.0544575887315472,0.00702652011242988,0.0977200773849536,0.45777573724699,-0.0584468268118252,-0.123986959677935,0.0866101088849405,0.0653521311844787,0.0176577878486037,0.00211104945096303,0.136087517322749,0,0.15656701070532,0.0786859227123475,-0.0245627253631537,0.164563026999396,0.0677931267972615,0.0168951769408576,0,-0.165963123388592,0,-0.0620637325458159,-0.110774409692317,-0.215075024782649,0.37994190493326,0,-0.25665191895952,-0.0173281897756203,0,0,0,0,-0.0239483372902628,-0.473481616714546,-0.122618684725551,-0.105092893280564,0,-0.221517175260705,0,0.0677931267972615,-0.118688664122714,0.030452582983756,0,-0.0148350156533624,0.0797217605740126,-0.0995750653002254,0.108243276363103,0.224214349798037,0,-0.645700337992725,0,0,0.427441866293951,0,-0.280809753204882,-0.253326341486756,-0.01452578268347,-0.074726246055625,0,0,0.088400854782969,0,0.171231018479657,0.0301983656337895,0,0.147664471803904,0.222345457763618,0,0,0,0,0,0,0,0,0,0,0,0.00126017844828197,0.101284635835257,0,0.0598226467574203,0,0,0,0,0,-0.00997261433030164,0.0144486317313367,0,0.711654731996299,0.063577899793818,0.180967572337787,0,0,0,0,0.265333390764867,0.198247032300814,0,-0.0640695797003702,0,0,0,0,0.0402777562551652,0,0,0,0.0677931267972615,0.0686882889907125,0.201843570722322,0,0,0,0.027030586412417,0,0,0,0,-0.267407962032606,0,0.0677931267972615,0.659963875053451,0,-0.27078262425279,-0.0815818795468414,0,-0.132960446099674,-0.146452972141391,0.495517352089058,0,0,-0.193554004992626,0,0.0677931267972615,0.284932958450835,0,0.178063486278075,0.0338965633986308,0,0,0,0,0.126418746044377,0,-0.214314512399756,0.12086283058208,0,0,0,0,0.126418746044377,0,0.126418746044377,0,0,0,-0.017668620602336,0.0341946893858661,0,0,0,0,0,0.0677931267972615,0,0.00979054031972765,-0.0659933056563675,0,0,0,0,0,0.0677931267972615,0,0,0.116511819469294,0,0,0,0,0,-0.0291992344453436,0,0,0,0,0.0929934009478999,0,0,-0.209569005396253,0,0,0,0,0,0,0,0,0,0.673641356777498,0,0,0,-0.123319086035448,-0.1320804316184,0,0,0,0,0,0,0,0.0291516898081169,0,0.178063486278075,0,0,0.11032997608906,0,0,0,0.324862956991767,0,0.0638963197116508,0,0,0,0,0,0,0.0338965633986308,0,0,0,0,0,0,0,0,0,0,0.379092027166936,0,0,0,0.1657589719727,0.0677931267972615,-0.0519111361788303,-0.055409737776524,0,0,0.11921584189723,0,0,0,0,0,0,0.0807667508704915,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.00096148040645763,0,0,0,0,0,0,0,0.028460849776319,0,0,-0.0920328098005262,0,0,0,0,0.126148658880489,0,0.0496917947835695,0.42770903562888,-0.0185597531319991,0,0,0.178063486278075,0.00882380053973325,0,0,0,0,0.00101573937836015,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0855298835511661,0,0,0,0,0,0,0,0,0,0,0,0,0.0632093730221885,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0677931267972615,0,0,0,0,0,0,0,-0.000114799876785747,0.126418746044377,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.0122253414713769,0,0,0,-0.0866674836126672,0,0,0,0,0,0,0.0677931267972615,0,0.126418746044377,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.00394527255485722,0,0,0,0,0,0,0,0,1.25679436612607,0,0,0,0,-0.04822207523905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| |||
|rna_box=111 | |||
|rna_catalog_number= | |||
|rna_concentration=1.61217 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.13 | |||
|rna_od260/280=2.06 | |||
|rna_position=F2 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=111F2 | |||
|rna_weight_ug=120.91275 | |||
|sample_age=unknown | |||
|sample_category=cell lines | |||
|sample_cell_catalog=CRL5946 | |||
|sample_cell_line=NCI-H2452 | |||
|sample_cell_lot= | |||
|sample_cell_type=mesothelial cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=ATCC | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=mesothelioma | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;3.84762245686818e-262!GO:0043226;organelle;4.4632386543408e-213!GO:0043229;intracellular organelle;1.49385550660119e-212!GO:0043231;intracellular membrane-bound organelle;1.36264178068981e-211!GO:0043227;membrane-bound organelle;2.00180734418694e-211!GO:0005737;cytoplasm;6.23509585205153e-188!GO:0044422;organelle part;1.05750264002474e-157!GO:0044446;intracellular organelle part;3.86173964435853e-156!GO:0044444;cytoplasmic part;3.86951229060887e-134!GO:0032991;macromolecular complex;3.48593473295027e-107!GO:0044237;cellular metabolic process;2.54891607128885e-96!GO:0044238;primary metabolic process;8.17928853262975e-95!GO:0005634;nucleus;2.83876024076633e-93!GO:0030529;ribonucleoprotein complex;1.38720420134556e-91!GO:0043170;macromolecule metabolic process;1.62744999464517e-90!GO:0044428;nuclear part;1.2883571375254e-81!GO:0003723;RNA binding;4.83240833728833e-79!GO:0043233;organelle lumen;1.907816628774e-76!GO:0031974;membrane-enclosed lumen;1.907816628774e-76!GO:0005515;protein binding;4.16392354754591e-76!GO:0005739;mitochondrion;8.11053228924719e-68!GO:0005840;ribosome;2.65200520929683e-55!GO:0016043;cellular component organization and biogenesis;5.14417170471926e-55!GO:0043234;protein complex;6.5049331034016e-54!GO:0006412;translation;2.71392840154501e-53!GO:0043283;biopolymer metabolic process;8.50775106701083e-53!GO:0006396;RNA processing;6.70407337953452e-52!GO:0031090;organelle membrane;2.48187064837023e-51!GO:0019538;protein metabolic process;4.69484841800946e-50!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.78135783873905e-48!GO:0003735;structural constituent of ribosome;7.12174248841004e-48!GO:0031981;nuclear lumen;1.11029113741105e-47!GO:0010467;gene expression;9.91189292371525e-46!GO:0033036;macromolecule localization;2.24623064282337e-45!GO:0044429;mitochondrial part;3.39077766263619e-45!GO:0015031;protein transport;1.689272242254e-44!GO:0044267;cellular protein metabolic process;9.47128517395912e-44!GO:0044260;cellular macromolecule metabolic process;1.54673016811819e-43!GO:0031967;organelle envelope;3.02270333735015e-42!GO:0031975;envelope;7.72734528998653e-42!GO:0005829;cytosol;9.59657742805722e-42!GO:0043228;non-membrane-bound organelle;1.27970597046462e-41!GO:0043232;intracellular non-membrane-bound organelle;1.27970597046462e-41!GO:0008104;protein localization;2.5762856086059e-41!GO:0045184;establishment of protein localization;8.1316759999154e-41!GO:0033279;ribosomal subunit;1.38109123614701e-40!GO:0009058;biosynthetic process;2.04238370977671e-40!GO:0044249;cellular biosynthetic process;4.32030174910291e-40!GO:0009059;macromolecule biosynthetic process;4.36570786570022e-40!GO:0006996;organelle organization and biogenesis;5.25700029726839e-40!GO:0006259;DNA metabolic process;8.33531251977813e-40!GO:0016071;mRNA metabolic process;2.45965141161094e-39!GO:0008380;RNA splicing;4.30049125369174e-38!GO:0046907;intracellular transport;1.6504172130192e-37!GO:0065003;macromolecular complex assembly;8.79915512324913e-36!GO:0006397;mRNA processing;2.84045674956039e-34!GO:0022613;ribonucleoprotein complex biogenesis and assembly;8.84160018658254e-33!GO:0022607;cellular component assembly;1.00247595221088e-32!GO:0006886;intracellular protein transport;3.15097108370844e-31!GO:0003676;nucleic acid binding;5.70361749788416e-30!GO:0007049;cell cycle;6.68202485045395e-30!GO:0005654;nucleoplasm;3.12557530267319e-29!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.6480141773994e-29!GO:0005740;mitochondrial envelope;7.09178386382343e-29!GO:0031966;mitochondrial membrane;1.89636598417438e-27!GO:0005681;spliceosome;5.62971960961175e-27!GO:0019866;organelle inner membrane;2.12903615801956e-26!GO:0000166;nucleotide binding;8.03452163449326e-26!GO:0017111;nucleoside-triphosphatase activity;1.34479623863705e-25!GO:0016462;pyrophosphatase activity;1.37676973052252e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.47634105713385e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;2.49225127055686e-25!GO:0005743;mitochondrial inner membrane;2.47200922388485e-24!GO:0044445;cytosolic part;6.00194039090213e-24!GO:0051649;establishment of cellular localization;9.35983006661723e-24!GO:0051641;cellular localization;1.1640741784939e-23!GO:0044451;nucleoplasm part;4.0225947539484e-23!GO:0006119;oxidative phosphorylation;1.34126741621525e-22!GO:0022402;cell cycle process;3.04932151764985e-22!GO:0000278;mitotic cell cycle;6.43289096595743e-22!GO:0006974;response to DNA damage stimulus;7.00121811725846e-22!GO:0005694;chromosome;1.05996684052306e-21!GO:0044427;chromosomal part;4.20275716217883e-21!GO:0015934;large ribosomal subunit;4.32752084371157e-21!GO:0012505;endomembrane system;5.81526275638796e-21!GO:0006457;protein folding;7.77883997879428e-21!GO:0016070;RNA metabolic process;1.37598020085635e-20!GO:0015935;small ribosomal subunit;1.63775874678464e-20!GO:0005730;nucleolus;6.03698276620063e-20!GO:0044265;cellular macromolecule catabolic process;1.5688901076696e-19!GO:0022618;protein-RNA complex assembly;1.61570461353057e-19!GO:0006281;DNA repair;2.28881209704369e-19!GO:0016874;ligase activity;3.24977353769915e-19!GO:0031980;mitochondrial lumen;3.33229501839165e-19!GO:0005759;mitochondrial matrix;3.33229501839165e-19!GO:0043285;biopolymer catabolic process;3.94356931737858e-19!GO:0044455;mitochondrial membrane part;4.42762007674699e-19!GO:0000502;proteasome complex (sensu Eukaryota);9.54750164127158e-19!GO:0051603;proteolysis involved in cellular protein catabolic process;1.41475972231901e-18!GO:0019941;modification-dependent protein catabolic process;2.32286285317726e-18!GO:0043632;modification-dependent macromolecule catabolic process;2.32286285317726e-18!GO:0032553;ribonucleotide binding;2.39604840344879e-18!GO:0032555;purine ribonucleotide binding;2.39604840344879e-18!GO:0044257;cellular protein catabolic process;3.55586370112583e-18!GO:0005783;endoplasmic reticulum;3.59667502130725e-18!GO:0006511;ubiquitin-dependent protein catabolic process;5.94427765866868e-18!GO:0017076;purine nucleotide binding;7.40988812392781e-18!GO:0008134;transcription factor binding;7.48144414390279e-18!GO:0009057;macromolecule catabolic process;8.39142879441985e-18!GO:0051276;chromosome organization and biogenesis;1.13302467971982e-17!GO:0006512;ubiquitin cycle;1.45474947001184e-17!GO:0022403;cell cycle phase;1.61633940958148e-17!GO:0000087;M phase of mitotic cell cycle;1.94723975382914e-17!GO:0007067;mitosis;3.21465910257837e-17!GO:0006260;DNA replication;3.54589728955967e-17!GO:0030163;protein catabolic process;4.84451256158949e-17!GO:0048770;pigment granule;2.17891486862338e-16!GO:0042470;melanosome;2.17891486862338e-16!GO:0005524;ATP binding;4.39168546840094e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.44883710879902e-16!GO:0051301;cell division;5.4631959200907e-16!GO:0006605;protein targeting;5.6203341368926e-16!GO:0008135;translation factor activity, nucleic acid binding;6.52641008259162e-16!GO:0005761;mitochondrial ribosome;6.61019933887861e-16!GO:0000313;organellar ribosome;6.61019933887861e-16!GO:0005746;mitochondrial respiratory chain;7.13380282747012e-16!GO:0032559;adenyl ribonucleotide binding;1.25719082919578e-15!GO:0051186;cofactor metabolic process;3.05325715405984e-15!GO:0009719;response to endogenous stimulus;3.13761840359241e-15!GO:0000279;M phase;4.73361249552437e-15!GO:0030554;adenyl nucleotide binding;6.07916179622572e-15!GO:0044248;cellular catabolic process;7.07644656133969e-15!GO:0044432;endoplasmic reticulum part;7.43237692144307e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);7.44884662892507e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.06132550362035e-14!GO:0003954;NADH dehydrogenase activity;1.06132550362035e-14!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.06132550362035e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.06132550362035e-14!GO:0016887;ATPase activity;2.07291874579773e-14!GO:0042254;ribosome biogenesis and assembly;2.55890225905584e-14!GO:0042623;ATPase activity, coupled;3.21455447771097e-14!GO:0051082;unfolded protein binding;3.66642489660116e-14!GO:0005635;nuclear envelope;4.83290483170532e-14!GO:0048193;Golgi vesicle transport;6.6742246839595e-14!GO:0044453;nuclear membrane part;8.90000668419056e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;8.9061817471282e-14!GO:0000375;RNA splicing, via transesterification reactions;8.9061817471282e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;8.9061817471282e-14!GO:0005794;Golgi apparatus;9.89155881956039e-14!GO:0042775;organelle ATP synthesis coupled electron transport;1.77580861441278e-13!GO:0042773;ATP synthesis coupled electron transport;1.77580861441278e-13!GO:0031965;nuclear membrane;2.08771952200401e-13!GO:0030964;NADH dehydrogenase complex (quinone);5.13177808643368e-13!GO:0045271;respiratory chain complex I;5.13177808643368e-13!GO:0005747;mitochondrial respiratory chain complex I;5.13177808643368e-13!GO:0006325;establishment and/or maintenance of chromatin architecture;6.46457289684567e-13!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;6.49181441620577e-13!GO:0003743;translation initiation factor activity;1.34026654244765e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.42348322118651e-12!GO:0006413;translational initiation;1.9297260866266e-12!GO:0016192;vesicle-mediated transport;2.32154026620918e-12!GO:0006323;DNA packaging;2.37914454471732e-12!GO:0016604;nuclear body;3.06941799979389e-12!GO:0004386;helicase activity;3.26888161627806e-12!GO:0003712;transcription cofactor activity;3.27513778248031e-12!GO:0006732;coenzyme metabolic process;6.80996113241245e-12!GO:0006399;tRNA metabolic process;6.97186747192018e-12!GO:0043412;biopolymer modification;1.00557673744142e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.46600824696284e-11!GO:0065004;protein-DNA complex assembly;3.79614491968399e-11!GO:0000785;chromatin;5.59772882805665e-11!GO:0005789;endoplasmic reticulum membrane;6.14107050476046e-11!GO:0006446;regulation of translational initiation;6.16228512528885e-11!GO:0005643;nuclear pore;6.3261757120682e-11!GO:0012501;programmed cell death;6.56498794300774e-11!GO:0006915;apoptosis;7.25600436167747e-11!GO:0009055;electron carrier activity;8.9235823883532e-11!GO:0008639;small protein conjugating enzyme activity;9.09923421884889e-11!GO:0006913;nucleocytoplasmic transport;1.62475636354276e-10!GO:0051726;regulation of cell cycle;1.68462928719835e-10!GO:0000074;regulation of progression through cell cycle;1.73167161003264e-10!GO:0008026;ATP-dependent helicase activity;1.97540308481599e-10!GO:0004842;ubiquitin-protein ligase activity;2.57285863251762e-10!GO:0006403;RNA localization;2.81572081631293e-10!GO:0051169;nuclear transport;3.54717176327292e-10!GO:0050657;nucleic acid transport;3.54717176327292e-10!GO:0051236;establishment of RNA localization;3.54717176327292e-10!GO:0050658;RNA transport;3.54717176327292e-10!GO:0065002;intracellular protein transport across a membrane;3.9157895970309e-10!GO:0019787;small conjugating protein ligase activity;4.56088123629369e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.63528672458576e-10!GO:0006464;protein modification process;6.47776374406262e-10!GO:0006366;transcription from RNA polymerase II promoter;6.54820028815724e-10!GO:0009259;ribonucleotide metabolic process;7.72788780199834e-10!GO:0006461;protein complex assembly;8.17684423236245e-10!GO:0008219;cell death;8.40567946054383e-10!GO:0016265;death;8.40567946054383e-10!GO:0016879;ligase activity, forming carbon-nitrogen bonds;8.61620995399657e-10!GO:0006163;purine nucleotide metabolic process;1.30765204238507e-09!GO:0006364;rRNA processing;1.50360717992565e-09!GO:0050794;regulation of cellular process;1.61061028311643e-09!GO:0009056;catabolic process;1.84412594998794e-09!GO:0015630;microtubule cytoskeleton;1.92814980078987e-09!GO:0008565;protein transporter activity;2.32418021986353e-09!GO:0006333;chromatin assembly or disassembly;2.36461721780452e-09!GO:0016072;rRNA metabolic process;3.23631958486215e-09!GO:0005793;ER-Golgi intermediate compartment;3.75727570236335e-09!GO:0009150;purine ribonucleotide metabolic process;3.94939489702148e-09!GO:0046930;pore complex;4.76343287028093e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.12754426342564e-09!GO:0016607;nuclear speck;5.47540327942959e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;5.47540327942959e-09!GO:0004812;aminoacyl-tRNA ligase activity;5.47540327942959e-09!GO:0016875;ligase activity, forming carbon-oxygen bonds;5.47540327942959e-09!GO:0003697;single-stranded DNA binding;6.86917456261563e-09!GO:0043566;structure-specific DNA binding;8.16826622620469e-09!GO:0051188;cofactor biosynthetic process;9.93070941432317e-09!GO:0043038;amino acid activation;1.13227923069648e-08!GO:0006418;tRNA aminoacylation for protein translation;1.13227923069648e-08!GO:0043039;tRNA aminoacylation;1.13227923069648e-08!GO:0016881;acid-amino acid ligase activity;1.23695871174009e-08!GO:0006164;purine nucleotide biosynthetic process;1.374859318646e-08!GO:0015986;ATP synthesis coupled proton transport;1.54896406055583e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.54896406055583e-08!GO:0009141;nucleoside triphosphate metabolic process;1.66110473693817e-08!GO:0030532;small nuclear ribonucleoprotein complex;1.70251325124618e-08!GO:0009260;ribonucleotide biosynthetic process;1.76907321592107e-08!GO:0016779;nucleotidyltransferase activity;1.80431562253772e-08!GO:0009199;ribonucleoside triphosphate metabolic process;1.83917164114178e-08!GO:0005839;proteasome core complex (sensu Eukaryota);1.83917164114178e-08!GO:0051028;mRNA transport;2.22335263665342e-08!GO:0017038;protein import;2.53109703088036e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.61759933168759e-08!GO:0009144;purine nucleoside triphosphate metabolic process;2.61759933168759e-08!GO:0007005;mitochondrion organization and biogenesis;2.71216930958809e-08!GO:0000775;chromosome, pericentric region;2.71798722587834e-08!GO:0043687;post-translational protein modification;2.73692086151919e-08!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.73692086151919e-08!GO:0003924;GTPase activity;3.74864195785106e-08!GO:0009152;purine ribonucleotide biosynthetic process;4.01477378118116e-08!GO:0006888;ER to Golgi vesicle-mediated transport;4.65971440454239e-08!GO:0046034;ATP metabolic process;5.66928135261675e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.27660767980249e-08!GO:0006334;nucleosome assembly;7.65149985778936e-08!GO:0009142;nucleoside triphosphate biosynthetic process;9.33614494481037e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;9.33614494481037e-08!GO:0019829;cation-transporting ATPase activity;9.33614494481037e-08!GO:0009060;aerobic respiration;9.85153257727672e-08!GO:0004298;threonine endopeptidase activity;1.24290375463356e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.33674960502008e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.33674960502008e-07!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.77698091349839e-07!GO:0006754;ATP biosynthetic process;2.33925454380811e-07!GO:0006753;nucleoside phosphate metabolic process;2.33925454380811e-07!GO:0051246;regulation of protein metabolic process;2.48374614651927e-07!GO:0006261;DNA-dependent DNA replication;2.52144065653862e-07!GO:0005819;spindle;2.57276347584754e-07!GO:0042981;regulation of apoptosis;2.6067644009227e-07!GO:0043067;regulation of programmed cell death;3.42274694688256e-07!GO:0045333;cellular respiration;3.47508683722928e-07!GO:0031497;chromatin assembly;3.85533604634992e-07!GO:0048475;coated membrane;3.89565507475059e-07!GO:0030117;membrane coat;3.89565507475059e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.27647297094499e-07!GO:0005813;centrosome;5.27736957410443e-07!GO:0005768;endosome;5.96009363445425e-07!GO:0000245;spliceosome assembly;6.44002230022165e-07!GO:0030120;vesicle coat;6.61925799416678e-07!GO:0030662;coated vesicle membrane;6.61925799416678e-07!GO:0009108;coenzyme biosynthetic process;6.75437288339829e-07!GO:0016469;proton-transporting two-sector ATPase complex;9.34135278424425e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;9.49079959048577e-07!GO:0005815;microtubule organizing center;9.541746267626e-07!GO:0016787;hydrolase activity;9.78503554648387e-07!GO:0016568;chromatin modification;1.12713021082092e-06!GO:0007051;spindle organization and biogenesis;1.19303127315007e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.25553952889673e-06!GO:0015078;hydrogen ion transmembrane transporter activity;1.2560474537511e-06!GO:0003714;transcription corepressor activity;1.41647550043133e-06!GO:0048523;negative regulation of cellular process;1.44437045391317e-06!GO:0005667;transcription factor complex;1.49525625260462e-06!GO:0009117;nucleotide metabolic process;1.49525625260462e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.79998536997979e-06!GO:0005657;replication fork;2.00569996416051e-06!GO:0045259;proton-transporting ATP synthase complex;2.37070907222355e-06!GO:0051427;hormone receptor binding;2.44172264057163e-06!GO:0043623;cellular protein complex assembly;2.77340503047578e-06!GO:0016564;transcription repressor activity;3.67303236192115e-06!GO:0006099;tricarboxylic acid cycle;4.62412085677777e-06!GO:0046356;acetyl-CoA catabolic process;4.62412085677777e-06!GO:0016491;oxidoreductase activity;4.76874378746518e-06!GO:0000151;ubiquitin ligase complex;4.84682859771868e-06!GO:0044431;Golgi apparatus part;5.2370964584716e-06!GO:0003713;transcription coactivator activity;5.34274777472966e-06!GO:0003724;RNA helicase activity;5.43138829533487e-06!GO:0016853;isomerase activity;5.71288842174798e-06!GO:0035257;nuclear hormone receptor binding;5.92287997027629e-06!GO:0051329;interphase of mitotic cell cycle;6.98375162212947e-06!GO:0032446;protein modification by small protein conjugation;8.04104159689649e-06!GO:0006084;acetyl-CoA metabolic process;8.09085272104068e-06!GO:0051325;interphase;8.1723076516141e-06!GO:0006752;group transfer coenzyme metabolic process;1.00922292666963e-05!GO:0005788;endoplasmic reticulum lumen;1.09292437431682e-05!GO:0006613;cotranslational protein targeting to membrane;1.12395062538751e-05!GO:0016567;protein ubiquitination;1.13571917890432e-05!GO:0005762;mitochondrial large ribosomal subunit;1.17105154318165e-05!GO:0000315;organellar large ribosomal subunit;1.17105154318165e-05!GO:0031988;membrane-bound vesicle;1.2529000815027e-05!GO:0016023;cytoplasmic membrane-bound vesicle;1.46985121334366e-05!GO:0044440;endosomal part;1.56981338707674e-05!GO:0010008;endosome membrane;1.56981338707674e-05!GO:0050789;regulation of biological process;1.62246667352933e-05!GO:0019222;regulation of metabolic process;1.87688896319733e-05!GO:0016740;transferase activity;1.98091858251784e-05!GO:0006916;anti-apoptosis;2.18893559104081e-05!GO:0006302;double-strand break repair;2.69041519746687e-05!GO:0048519;negative regulation of biological process;2.95236388938135e-05!GO:0051170;nuclear import;3.42776806645751e-05!GO:0007059;chromosome segregation;3.42988959896366e-05!GO:0043021;ribonucleoprotein binding;3.6001134376877e-05!GO:0006606;protein import into nucleus;3.89731609474551e-05!GO:0008094;DNA-dependent ATPase activity;4.07719184106285e-05!GO:0005769;early endosome;4.26388835439195e-05!GO:0016563;transcription activator activity;4.56187152313662e-05!GO:0006612;protein targeting to membrane;4.85679415261272e-05!GO:0030867;rough endoplasmic reticulum membrane;5.04123362663441e-05!GO:0000075;cell cycle checkpoint;5.05684204911108e-05!GO:0008654;phospholipid biosynthetic process;5.28533283672233e-05!GO:0005525;GTP binding;5.28533283672233e-05!GO:0009109;coenzyme catabolic process;5.63763992619668e-05!GO:0043069;negative regulation of programmed cell death;5.72428178049782e-05!GO:0007010;cytoskeleton organization and biogenesis;5.96854086154406e-05!GO:0045454;cell redox homeostasis;6.11473517088712e-05!GO:0000776;kinetochore;6.37371619970794e-05!GO:0051168;nuclear export;6.7856533570837e-05!GO:0051187;cofactor catabolic process;6.9970305389987e-05!GO:0003899;DNA-directed RNA polymerase activity;7.0729503043979e-05!GO:0043066;negative regulation of apoptosis;7.91959418526649e-05!GO:0000314;organellar small ribosomal subunit;8.02580962404537e-05!GO:0005763;mitochondrial small ribosomal subunit;8.02580962404537e-05!GO:0005773;vacuole;8.05649427813459e-05!GO:0006414;translational elongation;8.45460843609189e-05!GO:0051789;response to protein stimulus;8.45460843609189e-05!GO:0006986;response to unfolded protein;8.45460843609189e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;8.49542763362359e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;9.31150869715083e-05!GO:0003682;chromatin binding;9.81168985619561e-05!GO:0031968;organelle outer membrane;9.97819894025887e-05!GO:0006310;DNA recombination;0.000109434566637883!GO:0019843;rRNA binding;0.000111451490427439!GO:0005798;Golgi-associated vesicle;0.000117759937535755!GO:0031982;vesicle;0.000118977389467984!GO:0000139;Golgi membrane;0.000130849783460398!GO:0019867;outer membrane;0.000133072619840481!GO:0008033;tRNA processing;0.00013681898351092!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000146643142900173!GO:0031410;cytoplasmic vesicle;0.000160005558404912!GO:0031252;leading edge;0.000180489310499632!GO:0005905;coated pit;0.00018483722288899!GO:0016859;cis-trans isomerase activity;0.000190929177036746!GO:0030036;actin cytoskeleton organization and biogenesis;0.000196704255271763!GO:0045786;negative regulation of progression through cell cycle;0.000199782374277094!GO:0005048;signal sequence binding;0.000219613474262687!GO:0031324;negative regulation of cellular metabolic process;0.000228658905027969!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000230318884573974!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000230944893264936!GO:0008186;RNA-dependent ATPase activity;0.000230944893264936!GO:0051052;regulation of DNA metabolic process;0.00023126477268175!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000244020674344103!GO:0006626;protein targeting to mitochondrion;0.000276561402608058!GO:0000786;nucleosome;0.000279792372359931!GO:0007088;regulation of mitosis;0.000286750748880203!GO:0004576;oligosaccharyl transferase activity;0.000312104819776022!GO:0003690;double-stranded DNA binding;0.000336981625222638!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000352996760625456!GO:0015399;primary active transmembrane transporter activity;0.000352996760625456!GO:0008250;oligosaccharyl transferase complex;0.00036631064649806!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000369267362433987!GO:0033116;ER-Golgi intermediate compartment membrane;0.000382835112374749!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000411006492404771!GO:0015980;energy derivation by oxidation of organic compounds;0.000424538667576459!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000503923981052489!GO:0016044;membrane organization and biogenesis;0.000511113824181557!GO:0032561;guanyl ribonucleotide binding;0.000523252745565295!GO:0019001;guanyl nucleotide binding;0.000523252745565295!GO:0005770;late endosome;0.00053448858838212!GO:0005874;microtubule;0.000553855981078834!GO:0005885;Arp2/3 protein complex;0.000569168012503947!GO:0007052;mitotic spindle organization and biogenesis;0.000626039527270915!GO:0048522;positive regulation of cellular process;0.000629918105855594!GO:0004004;ATP-dependent RNA helicase activity;0.000647930427159802!GO:0016363;nuclear matrix;0.000648082134435956!GO:0009892;negative regulation of metabolic process;0.000648082134435956!GO:0005741;mitochondrial outer membrane;0.000664468921568131!GO:0008632;apoptotic program;0.000676751317198416!GO:0051252;regulation of RNA metabolic process;0.000711623968038982!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000714454058868494!GO:0019899;enzyme binding;0.000729724947036512!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00074460345170825!GO:0006839;mitochondrial transport;0.00076510938740988!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00079068533501248!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.000802539691709474!GO:0035258;steroid hormone receptor binding;0.000809299355436847!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00083569957036071!GO:0006091;generation of precursor metabolites and energy;0.000849531196982531!GO:0000323;lytic vacuole;0.00085711937637441!GO:0005764;lysosome;0.00085711937637441!GO:0015631;tubulin binding;0.000878218283919504!GO:0003684;damaged DNA binding;0.000878218283919504!GO:0003729;mRNA binding;0.000914023334432617!GO:0051920;peroxiredoxin activity;0.00107710055569442!GO:0006891;intra-Golgi vesicle-mediated transport;0.00109336694516587!GO:0044452;nucleolar part;0.0011069872056538!GO:0016310;phosphorylation;0.00115684271408295!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00118585880080766!GO:0007093;mitotic cell cycle checkpoint;0.00119362638186694!GO:0046474;glycerophospholipid biosynthetic process;0.00121453987682674!GO:0030663;COPI coated vesicle membrane;0.00124115738738362!GO:0030126;COPI vesicle coat;0.00124115738738362!GO:0043681;protein import into mitochondrion;0.0012541248928938!GO:0007243;protein kinase cascade;0.00125421040479223!GO:0006352;transcription initiation;0.00125798866767659!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00125798866767659!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00125798866767659!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00125798866767659!GO:0018196;peptidyl-asparagine modification;0.00127654047834668!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00127654047834668!GO:0046489;phosphoinositide biosynthetic process;0.0013102397704308!GO:0048471;perinuclear region of cytoplasm;0.00133413183581186!GO:0005684;U2-dependent spliceosome;0.00136347978344193!GO:0006793;phosphorus metabolic process;0.00136463081343207!GO:0006796;phosphate metabolic process;0.00136463081343207!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00136950651606817!GO:0006402;mRNA catabolic process;0.00143354326337158!GO:0006383;transcription from RNA polymerase III promoter;0.00155332880639926!GO:0006401;RNA catabolic process;0.00159853722047847!GO:0031323;regulation of cellular metabolic process;0.00168901052130822!GO:0051087;chaperone binding;0.00192460393744693!GO:0046467;membrane lipid biosynthetic process;0.00203924157783165!GO:0007017;microtubule-based process;0.00204744128981269!GO:0030029;actin filament-based process;0.00214231823488693!GO:0043284;biopolymer biosynthetic process;0.00215904511496019!GO:0015992;proton transport;0.00216722686723888!GO:0042802;identical protein binding;0.00228340157306325!GO:0016197;endosome transport;0.00229567349172034!GO:0007006;mitochondrial membrane organization and biogenesis;0.00232236679759256!GO:0006818;hydrogen transport;0.00236413299541364!GO:0030137;COPI-coated vesicle;0.00241811491588012!GO:0003678;DNA helicase activity;0.00245008885535934!GO:0016481;negative regulation of transcription;0.00263229312761233!GO:0005791;rough endoplasmic reticulum;0.002640103715868!GO:0031072;heat shock protein binding;0.00267129071465695!GO:0003746;translation elongation factor activity;0.00267821495891621!GO:0032508;DNA duplex unwinding;0.0027105124674393!GO:0032392;DNA geometric change;0.0027105124674393!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00277990639615861!GO:0008361;regulation of cell size;0.00284786989425145!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00299174592642871!GO:0003711;transcription elongation regulator activity;0.00303396944695921!GO:0030031;cell projection biogenesis;0.00306784716352686!GO:0030880;RNA polymerase complex;0.00307618715446182!GO:0048500;signal recognition particle;0.00309714319799428!GO:0043492;ATPase activity, coupled to movement of substances;0.00353153354309791!GO:0004527;exonuclease activity;0.00372587193480509!GO:0030132;clathrin coat of coated pit;0.00374064313384744!GO:0016049;cell growth;0.00381325404161073!GO:0048487;beta-tubulin binding;0.00382607319820473!GO:0008139;nuclear localization sequence binding;0.0038357687684452!GO:0043596;nuclear replication fork;0.00384451282568323!GO:0016126;sterol biosynthetic process;0.00393697921116715!GO:0000049;tRNA binding;0.00395952311424203!GO:0016741;transferase activity, transferring one-carbon groups;0.00397666859551469!GO:0008168;methyltransferase activity;0.00401395196608687!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0040456822134787!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0040456822134787!GO:0009165;nucleotide biosynthetic process;0.00405569863700887!GO:0030521;androgen receptor signaling pathway;0.0040616012381971!GO:0006405;RNA export from nucleus;0.00406774419255702!GO:0008312;7S RNA binding;0.00411393478224604!GO:0030118;clathrin coat;0.00425258858913135!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00426690448330691!GO:0051540;metal cluster binding;0.00432889117131138!GO:0051536;iron-sulfur cluster binding;0.00432889117131138!GO:0046483;heterocycle metabolic process;0.00451536318616909!GO:0005637;nuclear inner membrane;0.00451536318616909!GO:0006289;nucleotide-excision repair;0.00453017099133665!GO:0000059;protein import into nucleus, docking;0.00460203426786122!GO:0006284;base-excision repair;0.00461315315133662!GO:0016251;general RNA polymerase II transcription factor activity;0.00473354605011565!GO:0008022;protein C-terminus binding;0.00478000719965975!GO:0006268;DNA unwinding during replication;0.005238335626613!GO:0000922;spindle pole;0.00524222998593357!GO:0005876;spindle microtubule;0.00528603665333519!GO:0030659;cytoplasmic vesicle membrane;0.00535363425629009!GO:0031901;early endosome membrane;0.00546384505028366!GO:0016272;prefoldin complex;0.00560898047836207!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00563504193691381!GO:0000428;DNA-directed RNA polymerase complex;0.00563504193691381!GO:0050662;coenzyme binding;0.00563504193691381!GO:0006595;polyamine metabolic process;0.00563504193691381!GO:0006509;membrane protein ectodomain proteolysis;0.00566323834246758!GO:0033619;membrane protein proteolysis;0.00566323834246758!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00578616525009725!GO:0051539;4 iron, 4 sulfur cluster binding;0.00586690723556045!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00586690723556045!GO:0045047;protein targeting to ER;0.00586690723556045!GO:0006350;transcription;0.00586690723556045!GO:0030176;integral to endoplasmic reticulum membrane;0.00591704053638522!GO:0003702;RNA polymerase II transcription factor activity;0.00619965674820869!GO:0006497;protein amino acid lipidation;0.00655991105771638!GO:0006275;regulation of DNA replication;0.00658375516370327!GO:0030134;ER to Golgi transport vesicle;0.00677049960489164!GO:0001726;ruffle;0.00686184917011689!GO:0043488;regulation of mRNA stability;0.00692644294220067!GO:0043487;regulation of RNA stability;0.00692644294220067!GO:0000228;nuclear chromosome;0.007065978885018!GO:0000082;G1/S transition of mitotic cell cycle;0.00716547152245041!GO:0065007;biological regulation;0.0075154300537657!GO:0006695;cholesterol biosynthetic process;0.007810354233658!GO:0043022;ribosome binding;0.00791974638262304!GO:0009116;nucleoside metabolic process;0.00798319114553804!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.00802097556479458!GO:0030133;transport vesicle;0.0080448957967455!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00816795246364293!GO:0006740;NADPH regeneration;0.00816795246364293!GO:0006098;pentose-phosphate shunt;0.00816795246364293!GO:0030384;phosphoinositide metabolic process;0.00826944335555469!GO:0050681;androgen receptor binding;0.0082846949494816!GO:0006950;response to stress;0.0084693857637464!GO:0009112;nucleobase metabolic process;0.0084693857637464!GO:0007040;lysosome organization and biogenesis;0.00852386297061868!GO:0046966;thyroid hormone receptor binding;0.00989123595264856!GO:0051287;NAD binding;0.0100123996615159!GO:0003756;protein disulfide isomerase activity;0.0100281276983863!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0100281276983863!GO:0008610;lipid biosynthetic process;0.0101166960794304!GO:0006650;glycerophospholipid metabolic process;0.0101792289925805!GO:0032200;telomere organization and biogenesis;0.0103870299736364!GO:0000723;telomere maintenance;0.0103870299736364!GO:0004674;protein serine/threonine kinase activity;0.0104662151941033!GO:0007021;tubulin folding;0.010625648600989!GO:0005853;eukaryotic translation elongation factor 1 complex;0.010625648600989!GO:0006144;purine base metabolic process;0.0107036060773895!GO:0006739;NADP metabolic process;0.0110680857776003!GO:0005832;chaperonin-containing T-complex;0.0110725094070321!GO:0006007;glucose catabolic process;0.0110838612376315!GO:0030032;lamellipodium biogenesis;0.011457782449211!GO:0006611;protein export from nucleus;0.0116303547347276!GO:0006672;ceramide metabolic process;0.0119241035467404!GO:0051128;regulation of cellular component organization and biogenesis;0.0120468916746226!GO:0017166;vinculin binding;0.0123941049014442!GO:0043624;cellular protein complex disassembly;0.0123941049014442!GO:0030027;lamellipodium;0.0123941049014442!GO:0032984;macromolecular complex disassembly;0.0125045280649355!GO:0000819;sister chromatid segregation;0.0125541332417042!GO:0042393;histone binding;0.0125735252287724!GO:0044262;cellular carbohydrate metabolic process;0.012587139202184!GO:0000725;recombinational repair;0.0130083940386482!GO:0000724;double-strand break repair via homologous recombination;0.0130083940386482!GO:0000070;mitotic sister chromatid segregation;0.0130088607006964!GO:0044433;cytoplasmic vesicle part;0.0130088607006964!GO:0008092;cytoskeletal protein binding;0.0134374262464914!GO:0007033;vacuole organization and biogenesis;0.0136312875015277!GO:0008408;3'-5' exonuclease activity;0.013887350519669!GO:0065009;regulation of a molecular function;0.013895427806852!GO:0030658;transport vesicle membrane;0.013895427806852!GO:0008234;cysteine-type peptidase activity;0.0139038658435146!GO:0030127;COPII vesicle coat;0.0140562436509089!GO:0012507;ER to Golgi transport vesicle membrane;0.0140562436509089!GO:0043601;nuclear replisome;0.0147311587294567!GO:0030894;replisome;0.0147311587294567!GO:0042770;DNA damage response, signal transduction;0.0147547234077594!GO:0030119;AP-type membrane coat adaptor complex;0.0157573318177731!GO:0001558;regulation of cell growth;0.0157573318177731!GO:0009451;RNA modification;0.0158061481258654!GO:0005862;muscle thin filament tropomyosin;0.015815619422457!GO:0006376;mRNA splice site selection;0.0158169593918627!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0158169593918627!GO:0008637;apoptotic mitochondrial changes;0.0160987756392948!GO:0008180;signalosome;0.0165848973058311!GO:0006984;ER-nuclear signaling pathway;0.0167218052623346!GO:0044454;nuclear chromosome part;0.0167218052623346!GO:0006506;GPI anchor biosynthetic process;0.0173346333918103!GO:0016584;nucleosome positioning;0.017826600693965!GO:0010468;regulation of gene expression;0.0178282521792432!GO:0046519;sphingoid metabolic process;0.0179398877018642!GO:0000339;RNA cap binding;0.0179453092072874!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0180871428690236!GO:0042158;lipoprotein biosynthetic process;0.0184537958873397!GO:0009967;positive regulation of signal transduction;0.0185502248164085!GO:0012506;vesicle membrane;0.0189535261731956!GO:0031625;ubiquitin protein ligase binding;0.0191073615277619!GO:0004177;aminopeptidase activity;0.0194040513522832!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0200223092675897!GO:0015002;heme-copper terminal oxidase activity;0.0200223092675897!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0200223092675897!GO:0004129;cytochrome-c oxidase activity;0.0200223092675897!GO:0007034;vacuolar transport;0.0201101429528141!GO:0030833;regulation of actin filament polymerization;0.0205982318251029!GO:0000152;nuclear ubiquitin ligase complex;0.0207781991194241!GO:0009615;response to virus;0.0207781991194241!GO:0000209;protein polyubiquitination;0.0211710883382578!GO:0006520;amino acid metabolic process;0.0215926569250138!GO:0000781;chromosome, telomeric region;0.0218240380912736!GO:0000096;sulfur amino acid metabolic process;0.0222006401204819!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0223874192940912!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0225227074491473!GO:0004518;nuclease activity;0.0225608524717016!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0228909170904117!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0230000565303374!GO:0006778;porphyrin metabolic process;0.0230534862123791!GO:0033013;tetrapyrrole metabolic process;0.0230534862123791!GO:0005758;mitochondrial intermembrane space;0.0231569221689295!GO:0043241;protein complex disassembly;0.0231569221689295!GO:0031124;mRNA 3'-end processing;0.0232978126080835!GO:0006505;GPI anchor metabolic process;0.0233989612910734!GO:0030131;clathrin adaptor complex;0.0237852813274819!GO:0006779;porphyrin biosynthetic process;0.0249058538112881!GO:0033014;tetrapyrrole biosynthetic process;0.0249058538112881!GO:0006733;oxidoreduction coenzyme metabolic process;0.024921519446517!GO:0031529;ruffle organization and biogenesis;0.0251892029908099!GO:0031570;DNA integrity checkpoint;0.0251892029908099!GO:0045893;positive regulation of transcription, DNA-dependent;0.0257301255712423!GO:0030660;Golgi-associated vesicle membrane;0.025980069351109!GO:0007004;telomere maintenance via telomerase;0.025980069351109!GO:0008538;proteasome activator activity;0.0264666702012829!GO:0033559;unsaturated fatty acid metabolic process;0.0269787546879972!GO:0006636;unsaturated fatty acid biosynthetic process;0.0269787546879972!GO:0004532;exoribonuclease activity;0.027091990957548!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.027091990957548!GO:0005774;vacuolar membrane;0.0273149252281792!GO:0048468;cell development;0.0273980879735163!GO:0030041;actin filament polymerization;0.0275313393540451!GO:0007346;regulation of progression through mitotic cell cycle;0.0277371151347948!GO:0045941;positive regulation of transcription;0.0277990065668477!GO:0006360;transcription from RNA polymerase I promoter;0.0279143974067397!GO:0006417;regulation of translation;0.0280103528481356!GO:0005869;dynactin complex;0.0286399276863799!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0295508718250337!GO:0031970;organelle envelope lumen;0.0297708525755492!GO:0006270;DNA replication initiation;0.029990917247708!GO:0022415;viral reproductive process;0.0305849196713122!GO:0006266;DNA ligation;0.0306817878045691!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0306817878045691!GO:0010257;NADH dehydrogenase complex assembly;0.0306817878045691!GO:0033108;mitochondrial respiratory chain complex assembly;0.0306817878045691!GO:0006354;RNA elongation;0.0309423819504742!GO:0043065;positive regulation of apoptosis;0.0312941215885177!GO:0030518;steroid hormone receptor signaling pathway;0.0312941215885177!GO:0005784;translocon complex;0.0313859216215512!GO:0006400;tRNA modification;0.0315381174675671!GO:0043281;regulation of caspase activity;0.0316025150016957!GO:0046822;regulation of nucleocytoplasmic transport;0.0316532287387197!GO:0045045;secretory pathway;0.0316532287387197!GO:0048518;positive regulation of biological process;0.0319899095172696!GO:0008243;plasminogen activator activity;0.0320241264925206!GO:0000792;heterochromatin;0.0320241264925206!GO:0031577;spindle checkpoint;0.0322185729434997!GO:0000118;histone deacetylase complex;0.0322923848746606!GO:0008017;microtubule binding;0.0323464882771212!GO:0022411;cellular component disassembly;0.0323952896725401!GO:0017134;fibroblast growth factor binding;0.0325117069837323!GO:0022890;inorganic cation transmembrane transporter activity;0.0330321869736972!GO:0006378;mRNA polyadenylation;0.0331625406354084!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.035366755468006!GO:0008601;protein phosphatase type 2A regulator activity;0.035401759420932!GO:0005663;DNA replication factor C complex;0.0356799417319888!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0360989691390063!GO:0006897;endocytosis;0.0367494485637518!GO:0010324;membrane invagination;0.0367494485637518!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.0367996820456222!GO:0004003;ATP-dependent DNA helicase activity;0.0368883941024228!GO:0043189;H4/H2A histone acetyltransferase complex;0.0372903842030913!GO:0007050;cell cycle arrest;0.0373872126062472!GO:0030125;clathrin vesicle coat;0.037543988820287!GO:0030665;clathrin coated vesicle membrane;0.037543988820287!GO:0043154;negative regulation of caspase activity;0.0382915740761812!GO:0019752;carboxylic acid metabolic process;0.0387383715935694!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0401106412510351!GO:0007264;small GTPase mediated signal transduction;0.0401106412510351!GO:0033673;negative regulation of kinase activity;0.0401106412510351!GO:0006469;negative regulation of protein kinase activity;0.0401106412510351!GO:0046112;nucleobase biosynthetic process;0.0401838875247849!GO:0000910;cytokinesis;0.0403884094749301!GO:0043068;positive regulation of programmed cell death;0.0403884094749301!GO:0030433;ER-associated protein catabolic process;0.0403884094749301!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0403884094749301!GO:0016860;intramolecular oxidoreductase activity;0.0405343595408395!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.0406795493923484!GO:0051348;negative regulation of transferase activity;0.0406795493923484!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0410516323128818!GO:0006082;organic acid metabolic process;0.0413776665918504!GO:0051053;negative regulation of DNA metabolic process;0.0414602874919332!GO:0016615;malate dehydrogenase activity;0.0421337336693765!GO:0008320;protein transmembrane transporter activity;0.0421735432152301!GO:0003725;double-stranded RNA binding;0.042188771351441!GO:0031902;late endosome membrane;0.0425535579003786!GO:0030508;thiol-disulfide exchange intermediate activity;0.0425535579003786!GO:0016408;C-acyltransferase activity;0.0425707578474027!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0425946242190646!GO:0046979;TAP2 binding;0.0437073891306127!GO:0046977;TAP binding;0.0437073891306127!GO:0046978;TAP1 binding;0.0437073891306127!GO:0046128;purine ribonucleoside metabolic process;0.0437409790270968!GO:0042278;purine nucleoside metabolic process;0.0437409790270968!GO:0030100;regulation of endocytosis;0.0441045576170272!GO:0009303;rRNA transcription;0.0441045576170272!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0441076828474481!GO:0035267;NuA4 histone acetyltransferase complex;0.0441076828474481!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0442514401935056!GO:0006892;post-Golgi vesicle-mediated transport;0.0446810824511799!GO:0008047;enzyme activator activity;0.0447658941027936!GO:0005680;anaphase-promoting complex;0.04478268941584!GO:0005850;eukaryotic translation initiation factor 2 complex;0.04478268941584!GO:0042168;heme metabolic process;0.0450073190451971!GO:0050811;GABA receptor binding;0.0450073190451971!GO:0048037;cofactor binding;0.0451160173278909!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0451268795730216!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.0457514585764294!GO:0022884;macromolecule transmembrane transporter activity;0.0458748637680499!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0458748637680499!GO:0000303;response to superoxide;0.0462366043604239!GO:0019783;small conjugating protein-specific protease activity;0.0465534449990729!GO:0044438;microbody part;0.0465999577718769!GO:0044439;peroxisomal part;0.0465999577718769!GO:0006338;chromatin remodeling;0.0469758137860434!GO:0006783;heme biosynthetic process;0.0484924417177755!GO:0047485;protein N-terminus binding;0.0487827380216907!GO:0005669;transcription factor TFIID complex;0.0494438652109782!GO:0001836;release of cytochrome c from mitochondria;0.0497542293482379 | |||
|sample_id=10848 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=mesothelium | |||
|top_motifs=NKX3-1:1.38316600569;IRF7:1.17000636985;NR3C1:1.16536007192;IRF1,2:1.01325343804;EN1,2:0.956108888008;RXR{A,B,G}:0.945097704975;E2F1..5:0.89767782082;CDX1,2,4:0.8842135223;GFI1:0.866802030688;HOX{A5,B5}:0.780647363184;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.732730698646;TEAD1:0.711483764879;ELK1,4_GABP{A,B1}:0.691101825344;NKX2-2,8:0.630358555213;TOPORS:0.602988000535;POU1F1:0.599135580531;STAT5{A,B}:0.581554721966;ADNP_IRX_SIX_ZHX:0.579689201204;ZIC1..3:0.577638020675;NRF1:0.56181123464;NFY{A,B,C}:0.554693966761;TEF:0.548400552532;ZBTB16:0.539923893266;XCPE1{core}:0.53383189284;NFIX:0.515000289394;NKX6-1,2:0.495265492365;LMO2:0.490541375699;PITX1..3:0.462614322373;TLX1..3_NFIC{dimer}:0.442075176455;EVI1:0.441882499904;NFE2L2:0.427432105579;POU5F1:0.3841116251;UFEwm:0.372731223986;AIRE:0.36417729937;HMGA1,2:0.355427374777;NFE2:0.344962048598;YY1:0.344182563988;FOXM1:0.341632653775;HSF1,2:0.317251412236;MYB:0.311480913707;STAT2,4,6:0.299825689904;NR6A1:0.285049573733;GZF1:0.28031002774;BACH2:0.27295084278;ZNF143:0.238706324556;ZNF148:0.236483872131;HOX{A4,D4}:0.214046461326;bHLH_family:0.191663893577;HOXA9_MEIS1:0.190552816333;ZNF384:0.170703484236;GATA4:0.165149937857;CEBPA,B_DDIT3:0.15646119556;HNF4A_NR2F1,2:0.147469570063;GFI1B:0.142686450861;FOS_FOS{B,L1}_JUN{B,D}:0.128032853099;EP300:0.0983862799666;HAND1,2:0.0806672789383;MYOD1:0.078002954327;PAX4:0.0719163414112;ELF1,2,4:0.0690485212632;FOXQ1:0.0679764574093;RFX1:0.0673723878762;HIF1A:0.0652583347119;SOX2:0.0646231299824;ALX4:0.0583725237058;PDX1:0.0557666320378;NFE2L1:0.0521397467149;MAZ:0.0463230865316;NR5A1,2:0.0453034909587;ZBTB6:0.0330587176438;PBX1:0.0136095514798;SREBF1,2:0.0120466486994;ZEB1:0.0107915530892;XBP1:0.00561466507194;CRX:0.00526527371622;SNAI1..3:-0.0181648613872;PAX5:-0.021371355969;GTF2I:-0.0457953164412;LHX3,4:-0.0481271178471;DMAP1_NCOR{1,2}_SMARC:-0.0550993341903;TFDP1:-0.0579140353585;PATZ1:-0.0675665100712;KLF4:-0.0689185604261;RXRA_VDR{dimer}:-0.0725073834946;FOXD3:-0.075196025656;FOXP1:-0.0952634220719;NFATC1..3:-0.10598933538;FOXA2:-0.109773833614;POU3F1..4:-0.118183723232;RREB1:-0.121315238164;OCT4_SOX2{dimer}:-0.129027740548;HLF:-0.142928337026;MZF1:-0.15103639506;PPARG:-0.156545831487;SOX{8,9,10}:-0.160112019196;PAX1,9:-0.161949369242;FOXO1,3,4:-0.179000846596;FOXP3:-0.186674792484;NFKB1_REL_RELA:-0.211039015615;TFAP2B:-0.222759247869;ALX1:-0.224208747563;PRRX1,2:-0.230212158886;NKX3-2:-0.230665352056;HBP1_HMGB_SSRP1_UBTF:-0.231896029859;ONECUT1,2:-0.238440762599;HNF1A:-0.244588011298;IKZF1:-0.245373352832;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.259998797973;HIC1:-0.263197370109;T:-0.277283665482;PAX8:-0.278106918018;ZNF423:-0.280646463935;POU2F1..3:-0.296980148739;GCM1,2:-0.307796399979;FOSL2:-0.326079370854;AHR_ARNT_ARNT2:-0.32873580834;IKZF2:-0.329401974875;TP53:-0.3598806181;NKX2-3_NKX2-5:-0.361719147847;ATF6:-0.366874720339;ARID5B:-0.378298543404;PRDM1:-0.381383275093;FOXL1:-0.383891649539;HES1:-0.384017096277;MTE{core}:-0.388521485072;AR:-0.394038555809;ESRRA:-0.400509647825;GLI1..3:-0.400738989092;TFCP2:-0.410163786907;SP1:-0.41832216335;ETS1,2:-0.422760398962;NANOG:-0.430381293511;PAX6:-0.437657577818;GTF2A1,2:-0.451141524255;SRF:-0.462471259761;SPIB:-0.468082027956;CDC5L:-0.46942184738;HOX{A6,A7,B6,B7}:-0.478031318242;LEF1_TCF7_TCF7L1,2:-0.488576634146;MAFB:-0.491913304242;SPZ1:-0.492133587096;FOX{I1,J2}:-0.492626896362;BREu{core}:-0.498018106126;RFX2..5_RFXANK_RFXAP:-0.502704409566;SPI1:-0.505724339455;SOX17:-0.518006432092;STAT1,3:-0.533862654123;TBP:-0.543550244833;RBPJ:-0.549818759443;NKX2-1,4:-0.560254366906;PAX2:-0.567593619058;GATA6:-0.576356547726;RUNX1..3:-0.577288651867;REST:-0.585866346104;EGR1..3:-0.605708796148;ATF5_CREB3:-0.626291016908;MED-1{core}:-0.62683543848;ZNF238:-0.633345402339;NR1H4:-0.634304321305;PAX3,7:-0.638725664866;TFAP2{A,C}:-0.643538620395;ESR1:-0.663344199872;TAL1_TCF{3,4,12}:-0.698283307496;CREB1:-0.698334842228;SMAD1..7,9:-0.723937382569;MEF2{A,B,C,D}:-0.734787321755;TFAP4:-0.742025439503;MYBL2:-0.743204694569;VSX1,2:-0.751813842915;ZFP161:-0.760295964373;MTF1:-0.761963395204;NHLH1,2:-0.776841756153;FOX{D1,D2}:-0.79860755558;DBP:-0.799611741207;NFIL3:-0.800144583199;MYFfamily:-0.828529992486;TGIF1:-0.829556889486;FOX{F1,F2,J1}:-0.835585368595;TBX4,5:-0.84019581591;CUX2:-0.861403862528;HMX1:-0.875130709888;EBF1:-0.894847436732;BPTF:-0.894956357121;ATF4:-0.905740046608;JUN:-1.00057281122;POU6F1:-1.02474359005;RORA:-1.04622374833;TLX2:-1.04986829179;FOXN1:-1.10804016253;ATF2:-1.19211342966;NANOG{mouse}:-1.29030515927;SOX5:-1.55687774011 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10848-111F2;search_select_hide=table117:FF:10848-111F2 | |||
}} | }} |
Latest revision as of 15:09, 3 June 2020
Name: | mesothelioma cell line:NCI-H2452 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13064 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13064
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13064
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.00744 |
10 | 10 | 0.115 |
100 | 100 | 0.192 |
101 | 101 | 0.54 |
102 | 102 | 0.793 |
103 | 103 | 0.418 |
104 | 104 | 0.467 |
105 | 105 | 0.466 |
106 | 106 | 0.0102 |
107 | 107 | 0.147 |
108 | 108 | 0.509 |
109 | 109 | 0.137 |
11 | 11 | 0.507 |
110 | 110 | 0.0328 |
111 | 111 | 0.708 |
112 | 112 | 0.266 |
113 | 113 | 0.0302 |
114 | 114 | 0.527 |
115 | 115 | 0.745 |
116 | 116 | 0.998 |
117 | 117 | 0.0218 |
118 | 118 | 0.102 |
119 | 119 | 0.792 |
12 | 12 | 0.453 |
120 | 120 | 0.453 |
121 | 121 | 0.181 |
122 | 122 | 0.75 |
123 | 123 | 0.752 |
124 | 124 | 0.121 |
125 | 125 | 0.783 |
126 | 126 | 0.714 |
127 | 127 | 0.93 |
128 | 128 | 0.00832 |
129 | 129 | 0.34 |
13 | 13 | 6.04063e-4 |
130 | 130 | 0.641 |
131 | 131 | 0.606 |
132 | 132 | 0.681 |
133 | 133 | 0.157 |
134 | 134 | 0.054 |
135 | 135 | 0.0236 |
136 | 136 | 0.0375 |
137 | 137 | 0.394 |
138 | 138 | 0.843 |
139 | 139 | 0.0841 |
14 | 14 | 0.736 |
140 | 140 | 0.93 |
141 | 141 | 0.526 |
142 | 142 | 0.109 |
143 | 143 | 0.0558 |
144 | 144 | 0.753 |
145 | 145 | 0.646 |
146 | 146 | 0.858 |
147 | 147 | 0.136 |
148 | 148 | 0.705 |
149 | 149 | 0.296 |
15 | 15 | 0.179 |
150 | 150 | 0.403 |
151 | 151 | 0.925 |
152 | 152 | 0.515 |
153 | 153 | 0.223 |
154 | 154 | 0.319 |
155 | 155 | 0.234 |
156 | 156 | 0.912 |
157 | 157 | 0.708 |
158 | 158 | 0.187 |
159 | 159 | 0.685 |
16 | 16 | 0.921 |
160 | 160 | 0.446 |
161 | 161 | 0.387 |
162 | 162 | 0.878 |
163 | 163 | 0.581 |
164 | 164 | 0.0138 |
165 | 165 | 0.354 |
166 | 166 | 0.669 |
167 | 167 | 0.58 |
168 | 168 | 0.0248 |
169 | 169 | 0.055 |
17 | 17 | 0.585 |
18 | 18 | 0.361 |
19 | 19 | 0.762 |
2 | 2 | 0.898 |
20 | 20 | 0.364 |
21 | 21 | 0.366 |
22 | 22 | 0.339 |
23 | 23 | 0.0661 |
24 | 24 | 0.251 |
25 | 25 | 0.352 |
26 | 26 | 0.21 |
27 | 27 | 0.866 |
28 | 28 | 0.496 |
29 | 29 | 8.46049e-4 |
3 | 3 | 0.249 |
30 | 30 | 0.307 |
31 | 31 | 0.105 |
32 | 32 | 0.162 |
33 | 33 | 0.172 |
34 | 34 | 0.184 |
35 | 35 | 0.674 |
36 | 36 | 0.3 |
37 | 37 | 0.595 |
38 | 38 | 0.811 |
39 | 39 | 0.309 |
4 | 4 | 0.249 |
40 | 40 | 0.058 |
41 | 41 | 0.0272 |
42 | 42 | 0.469 |
43 | 43 | 0.803 |
44 | 44 | 0.85 |
45 | 45 | 0.513 |
46 | 46 | 0.884 |
47 | 47 | 0.125 |
48 | 48 | 0.0625 |
49 | 49 | 0.321 |
5 | 5 | 0.26 |
50 | 50 | 0.742 |
51 | 51 | 0.825 |
52 | 52 | 0.298 |
53 | 53 | 0.76 |
54 | 54 | 0.477 |
55 | 55 | 0.712 |
56 | 56 | 0.308 |
57 | 57 | 0.34 |
58 | 58 | 0.357 |
59 | 59 | 0.907 |
6 | 6 | 0.566 |
60 | 60 | 0.18 |
61 | 61 | 0.211 |
62 | 62 | 0.168 |
63 | 63 | 0.533 |
64 | 64 | 0.414 |
65 | 65 | 0.242 |
66 | 66 | 0.0324 |
67 | 67 | 0.446 |
68 | 68 | 0.531 |
69 | 69 | 0.423 |
7 | 7 | 0.827 |
70 | 70 | 0.718 |
71 | 71 | 0.00154 |
72 | 72 | 0.523 |
73 | 73 | 0.52 |
74 | 74 | 0.477 |
75 | 75 | 0.00441 |
76 | 76 | 0.314 |
77 | 77 | 0.206 |
78 | 78 | 0.275 |
79 | 79 | 0.449 |
8 | 8 | 0.421 |
80 | 80 | 0.0875 |
81 | 81 | 0.564 |
82 | 82 | 0.748 |
83 | 83 | 0.973 |
84 | 84 | 0.651 |
85 | 85 | 0.0407 |
86 | 86 | 0.301 |
87 | 87 | 0.0481 |
88 | 88 | 0.765 |
89 | 89 | 0.894 |
9 | 9 | 0.429 |
90 | 90 | 0.552 |
91 | 91 | 0.612 |
92 | 92 | 0.0413 |
93 | 93 | 0.873 |
94 | 94 | 0.393 |
95 | 95 | 0.541 |
96 | 96 | 0.982 |
97 | 97 | 0.893 |
98 | 98 | 0.999 |
99 | 99 | 0.0831 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13064
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102424 mesothelioma cell line sample
FF:0103764 NCI cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000076 (squamous epithelial cell)
0000213 (lining cell)
0000215 (barrier cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0000077 (mesothelial cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
1115 (sarcoma)
UBERON: Anatomy
0002384 (connective tissue)
0000479 (tissue)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0001062 (anatomical entity)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100453 (fibroblast cell line sample)
0100400 (sarcoma cell line sample)
0100460 (fibrosarcoma cell line sample)
0102424 (mesothelioma cell line sample)
0103764 (NCI cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000222 (mesodermal cell)