FF:11231-116C7: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005408 | ||
| | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005408 | ||
|accession_numbers=CAGE;DRX008401;DRR009273;DRZ000698;DRZ002083;DRZ012048;DRZ013433 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037024;DRR041390;DRZ007032 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0000178,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0000179,UBERON:0000463,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0010317,UBERON:0002390,UBERON:0004535,UBERON:0002193,UBERON:0001009 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0002371,CL:0000219,CL:0000738,CL:0002087,CL:0000255,CL:0000226,CL:0000080,CL:0000842 | |||
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|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000135 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!2.27!186.50!PLEK;;chr11:47400078..47400106,-!p1@SPI1!2.25!175.75!SPI1;;chr16:85932760..85932775,+!p1@IRF8!2.05!110.62!IRF8;;chr5:133451294..133451310,+!p2@TCF7!1.99!95.94!TCF7;;chr12:54778471..54778528,-!p1@ZNF385A!1.92!81.67!ZNF385A;;chr1:25256756..25256774,-!p1@RUNX3!1.89!140.60!RUNX3;;chr3:63953435..63953499,+!p1@ATXN7!1.84!68.03!ATXN7;;chr4:109087445..109087463,-!p1@LEF1!1.82!65.34!LEF1;;chr19:54041669..54041697,+!p2@ZNF331!1.80!62.44!ZNF331;;chr7:50343634..50343717,+!p2@IKZF1!1.77!57.69!IKZF1;;chr19:54058073..54058088,+!p1@ZNF331!1.75!55.83!ZNF331;;chr2:192015701..192015743,-!p1@STAT4!1.73!71.54!STAT4;;chr6:106546808..106546833,+!p3@PRDM1!1.69!59.34!PRDM1;;chr5:133450365..133450444,+!p1@TCF7!1.67!202.01!TCF7;;chr2:231090433..231090469,+!p1@SP140!1.64!42.59!SP140;;chr2:157189180..157189290,-!p1@NR4A2!1.63!209.87!NR4A2;;chr6:91006518..91006570,-!p1@BACH2!1.61!88.08!BACH2;;chr3:71355163..71355209,-!p5@FOXP1!1.61!54.38!FOXP1;;chr7:50344289..50344323,+!p1@IKZF1!1.61!40.11!IKZF1;;chr9:117150254..117150271,-!p1@AKNA!1.58!97.59!AKNA;;chr6:391743..391759,+!p1@IRF4!1.58!36.80!IRF4;;chr2:145277640..145277771,-!p1@ZEB2!1.56!447.86!ZEB2;;chr3:18486354..18486377,-!p2@SATB1!1.52!40.11!SATB1;;chr2:100759010..100759035,-!p1@AFF3!1.49!29.57!AFF3;;chr20:50159198..50159299,-!p1@NFATC2!1.48!42.39!NFATC2;;chr17:45810594..45810608,+!p1@TBX21!1.46!28.12!TBX21;;chr15:60884706..60884743,-!p1@RORA!1.45!135.64!RORA;;chr11:47399947..47399961,-!p3@SPI1!1.45!27.29!SPI1;;chr11:47400062..47400077,-!p2@SPI1!1.45!26.88!SPI1;;chr2:192015750..192015793,-!p2@STAT4!1.44!35.77!STAT4;;chr10:35484053..35484076,+!p1@CREM!1.43!63.27!CREM;;chr19:50922187..50922204,+!p1@SPIB!1.43!25.85!SPIB;;chr14:75745523..75745537,+!p1@FOS!1.42!2872.42!FOS;;chr3:71542615..71542644,-!p12@FOXP1!1.42!25.43!FOXP1;;chr2:231090471..231090504,+!p2@SP140!1.41!24.61!SP140;;chr7:115670804..115670825,-!p1@TFEC!1.40!24.19!TFEC;;chr19:16435625..16435682,+!p1@KLF2!1.36!680.89!KLF2;;chr5:133451347..133451358,+!p3@TCF7!1.35!21.50!TCF7;;chr19:12902289..12902307,+!p1@JUNB!1.33!4455.44!JUNB;;chr12:54778351..54778378,-!p6@ZNF385A!1.33!20.47!ZNF385A;;chr6:106546834..106546850,+!p4@PRDM1!1.33!20.26!PRDM1;;chrX:106960285..106960299,-!p1@TSC22D3!1.31!500.79!TSC22D3;;chr2:61108695..61108753,+!p1@REL!1.31!130.47!REL;;chr10:8096631..8096660,+!p1@GATA3!1.29!22.12!GATA3;;chrX:106960180..106960197,-!p2@TSC22D3!1.28!67.20!TSC22D3;;chr11:111249993..111250006,-!p1@POU2AF1!1.28!18.20!POU2AF1;;chr19:45971246..45971265,+!p1@FOSB!1.27!318.01!FOSB;;chr20:56195474..56195506,-!p1@ZBP1!1.27!17.78!ZBP1;;chr2:100759037..100759058,-!p2@AFF3!1.27!17.58!AFF3;;chr17:38020392..38020477,-!p1@IKZF3!1.27!17.58!IKZF3;;chr9:102584262..102584276,+!p1@NR4A3!1.26!37.84!NR4A3;;chr7:50343895..50343936,+!p5@IKZF1!1.26!17.37!IKZF1;;chr2:145271342..145271377,-!p5@ZEB2!1.26!17.37!ZEB2;;chr12:72056800..72056834,+!p1@THAP2!1.25!22.54!THAP2;;chr11:47399996..47400014,-!p4@SPI1!1.25!16.95!SPI1;;chr21:36421535..36421610,-!p2@RUNX1!1.24!58.31!RUNX1;;chr5:88178983..88179012,-!p1@MEF2C!1.23!121.99!MEF2C;;chr4:109090075..109090095,-!p2@LEF1!1.23!15.92!LEF1;;chrX:106960221..106960236,-!p3@TSC22D3!1.22!43.21!TSC22D3;;chr3:71542684..71542720,-!p18@FOXP1!1.22!15.71!FOXP1;;chr2:70142232..70142251,+!p1@MXD1!1.21!83.74!MXD1;;chr10:35484090..35484104,+!p6@CREM!1.21!15.09!CREM;;chr20:39317868..39317884,-!p1@MAFB!1.19!168.93!MAFB;;chr13:41593425..41593480,-!p1@ELF1!1.19!90.98!ELF1;;chr3:39195075..39195088,-!p1@CSRNP1!1.19!89.53!CSRNP1;;chr10:8096772..8096787,+!p2@GATA3!1.19!16.95!GATA3;;chr7:50344251..50344288,+!p3@IKZF1!1.19!14.47!IKZF1;;chr4:106068026..106068084,+!p1@TET2!1.18!126.54!TET2;;chr1:25291475..25291511,-!p2@RUNX3!1.17!13.65!RUNX3;;chr19:42636586..42636607,-!p1@POU2F2!1.15!36.60!POU2F2;;chr14:35872962..35873025,-!p3@NFKBIA!1.15!33.08!NFKBIA;;chr6:91006575..91006602,-!p2@BACH2!1.15!19.64!BACH2;;chr6:144385698..144385742,-!p2@PLAGL1!1.15!15.92!PLAGL1;;chr12:54694758..54694805,-!p1@NFE2!1.15!15.92!NFE2;;chr9:102584241..102584261,+!p4@NR4A3!1.14!19.64!NR4A3;;chr17:37934365..37934387,-!p2@IKZF3!1.14!12.82!IKZF3;;chr12:52445218..52445237,+!p1@NR4A1!1.13!157.14!NR4A1;;chr11:128392273..128392308,-!p2@ETS1!1.13!52.52!ETS1;;chr2:68592394..68592405,+!p2@PLEK!1.13!12.61!PLEK;;chr6:106546786..106546802,+!p6@PRDM1!1.13!12.41!PRDM1;;chr4:38665769..38665801,+!p2@KLF3!1.12!109.38!KLF3;;chr11:47400032..47400043,-!p5@SPI1!1.12!12.20!SPI1;;chr2:43453734..43453751,-!p1@ZFP36L2!1.09!1188.09!ZFP36L2;;chr19:54041645..54041661,+!p5@ZNF331!1.09!11.17!ZNF331;;chr3:18487057..18487105,-!p4@SATB1!1.08!10.96!SATB1;;chr11:128563948..128564003,+!p1@FLI1!1.07!129.23!FLI1;;chr14:64970670..64970712,-!p3@ZBTB25!1.05!22.33!ZBTB25;;chr17:38020516..38020544,-!p5@IKZF3!1.05!10.34!IKZF3;;chr3:101568349..101568365,+!p1@NFKBIZ!1.04!526.84!NFKBIZ;;chr6:106546731..106546755,+!p5@PRDM1!1.04!9.92!PRDM1;;chr14:35873947..35873965,-!p1@NFKBIA!1.03!620.30!NFKBIA;;chr6:15246261..15246312,+!p1@JARID2!1.03!239.85!JARID2;;chr3:71179699..71179744,-!p2@FOXP1!1.03!73.40!FOXP1;;chr7:149470641..149470694,-!p1@ZNF467!1.03!44.25!ZNF467;;chrX:101186981..101187030,-!p1@ZMAT1!1.03!32.05!ZMAT1;;chr6:15246200..15246214,+!p2@JARID2!1.03!27.29!JARID2;;chr7:104654690..104654704,+!p2@MLL5!1.03!19.64!MLL5;;chr7:137620684..137620711,-!p4@CREB3L2!1.03!9.72!CREB3L2;;chr7:104654718..104654741,+!p3@MLL5!1.02!13.85!MLL5;;chr17:38020557..38020572,-!p4@IKZF3!1.02!9.51!IKZF3;;chr2:157189617..157189667,-!p4@NR4A2!1.02!9.51!NR4A2;;chr3:128212033..128212051,-!p1@GATA2!1.02!9.51!GATA2;;chr4:109089901..109089930,-!p3@LEF1!1.02!9.51!LEF1;;chr21:34442439..34442455,+!p1@OLIG1!1.02!9.51!OLIG1;;chr2:61108650..61108687,+!p2@REL!1.01!45.70!REL;;chr9:3525727..3525828,-!p2@RFX3!1.01!23.78!RFX3;;chr17:38497662..38497713,+!p4@RARA!1.01!10.75!RARA;;chr2:231090344..231090361,-!p3@SP110!1.01!9.30!SP110;;chr2:61108878..61108891,+!p5@REL!1.01!9.30!REL;;chr7:137620650..137620677,-!p3@CREB3L2!1.01!9.30!CREB3L2;;chr11:47400045..47400060,-!p6@SPI1!1.01!9.30!SPI1;;chr4:103422499..103422632,+!p1@NFKB1!1.00!191.47!NFKB1;;chr19:12721790..12721810,+!p2@ZNF791!1.00!25.23!ZNF791;;chr19:19729477..19729542,-!p1@PBX4!1.00!19.44!PBX4;;chr1:26697243..26697258,-!p1@ZNF683!1.00!8.89!ZNF683;;chr11:128392085..128392232,-!p1@ETS1!0.99!303.12!ETS1;;chr12:72056773..72056796,+!p3@THAP2!0.99!11.58!THAP2;;chr6:44233252..44233296,-!p1@NFKBIE!0.98!85.81!NFKBIE;;chr13:74707894..74707947,-!p6@KLF12!0.98!9.51!KLF12;;chr21:36421147..36421193,-!p10@RUNX1!0.98!8.48!RUNX1;;chr14:65569101..65569119,-!p3@MAX!0.97!27.09!MAX;;chr19:45251395..45251432,+!p8@BCL3!0.97!8.27!BCL3;;chr3:27763807..27763822,-!p1@EOMES!0.97!8.27!EOMES;;chr6:106534192..106534224,+!p1@PRDM1!0.96!23.36!PRDM1;;chr14:64971288..64971316,-!p2@ZBTB25!0.95!25.43!ZBTB25;;chr8:71316428..71316459,-!p2@NCOA2!0.95!13.44!NCOA2;;chr1:25256439..25256476,-!p3@RUNX3!0.95!7.86!RUNX3;;chr15:31619326..31619390,+!p2@KLF13!0.94!91.39!KLF13;;chr10:51572408..51572454,+!p3@NCOA4!0.94!47.14!NCOA4;;chr2:208394817..208394834,+!p3@CREB1!0.94!31.84!CREB1;;chr19:45252008..45252024,+!p2@BCL3!0.94!26.05!BCL3;;chr8:67525443..67525459,-!p2@MYBL1!0.94!11.79!MYBL1;;chr6:12009042..12009092,+!p6@HIVEP1!0.94!10.13!HIVEP1;;chr21:36421347..36421380,-!p8@RUNX1!0.94!7.65!RUNX1;;chr6:143266297..143266356,-!p1@HIVEP2!0.93!37.22!HIVEP2;;chr3:18480217..18480239,-!p3@SATB1!0.93!7.44!SATB1;;chr9:37034186..37034216,-!p2@PAX5!0.93!7.44!PAX5;;chr5:131826457..131826514,-!p1@IRF1!0.92!299.19!IRF1;;chr2:231084659..231084721,-!p1@SP110!0.92!176.79!SP110;;chr9:110252035..110252057,-!p1@KLF4!0.92!122.41!KLF4;;chr19:38085768..38085821,+!p1@ZNF540!0.92!11.17!ZNF540;;chr4:57522166..57522260,-!p2@HOPX!0.92!8.48!HOPX;;chr3:71542651..71542683,-!p22@FOXP1!0.92!7.24!FOXP1;;chr1:156470515..156470542,-!p2@MEF2D!0.91!39.08!MEF2D;;chr7:17338324..17338341,+!p3@AHR!0.91!24.81!AHR;;chr3:39195037..39195069,-!p2@CSRNP1!0.90!45.08!CSRNP1;;chr19:19779619..19779670,+!p1@ZNF101!0.90!20.06!ZNF101;;chr10:35416142..35416169,+!p3@CREM!0.90!19.02!CREM;;chr7:128577972..128578047,+!p1@IRF5!0.90!11.17!IRF5;;chr2:61108808..61108821,+!p3@REL!0.90!8.89!REL;;chr4:38665810..38665827,+!p1@KLF3!0.89!103.80!KLF3;;chr1:45805693..45805718,+!p3@TOE1!0.89!14.89!TOE1;;chr14:75988771..75988826,+!p1@BATF!0.89!9.10!BATF;;chr7:28725715..28725727,+!p3@CREB5!0.89!8.06!CREB5;;chr9:102584278..102584285,+!p5@NR4A3!0.89!6.82!NR4A3;;chr2:192015677..192015691,-!p3@STAT4!0.89!6.82!STAT4;;chr2:174828545..174828644,-!p1@SP3!0.88!105.45!SP3;;chr14:90085458..90085557,-!p1@FOXN3!0.88!72.78!FOXN3;;chr2:60780607..60780624,-!p2@BCL11A!0.88!21.09!BCL11A;;chr5:142782823..142782854,-!p3@NR3C1!0.88!9.72!NR3C1;;chr7:50348268..50348366,+!p4@IKZF1!0.88!6.62!IKZF1;;chr4:109089573..109089585,-!p8@LEF1!0.88!6.62!LEF1;;chr19:54041574..54041589,+!p6@ZNF331!0.88!6.62!ZNF331;;chr17:56565257..56565283,-!p2@HSF5!0.88!6.62!HSF5;;chr5:172483347..172483407,+!p1@C5orf41!0.87!51.69!CREBRF;;chr7:77428066..77428132,+!p2@PHTF2!0.87!44.04!PHTF2;;chr9:73028332..73028385,-!p3@KLF9!0.87!23.16!KLF9;;chr6:12008986..12009016,+!p3@HIVEP1!0.87!21.09!HIVEP1;;chr19:36391434..36391450,-!p1@NFKBID!0.87!13.03!NFKBID;;chr8:123793988..123794016,+!p1@ZHX2!0.87!11.79!ZHX2;;chr4:109088089..109088101,-!p11@LEF1!0.87!6.41!LEF1;;chr14:64971461..64971542,+!p1@ZBTB1!0.86!134.19!ZBTB1;;chr2:97202480..97202499,+!p1@ARID5A!0.86!66.99!ARID5A;;chr19:12273866..12273935,+!p1@ZNF136!0.86!59.34!ZNF136;;chr10:104154246..104154347,+!p3@NFKB2!0.86!40.53!NFKB2;;chr3:23986824..23986848,+!p2@NR1D2!0.86!37.22!NR1D2;;chr3:18466787..18466839,-!p1@SATB1!0.86!29.77!SATB1;;chr16:3313791..3313834,+!p2@ZNF263!0.86!14.47!ZNF263;;chr3:101546827..101546847,+!p2@NFKBIZ!0.86!9.10!NFKBIZ;;chr8:81397876..81397898,+!p5@ZBTB10!0.86!7.44!ZBTB10;;chr7:50344144..50344157,+!p6@IKZF1!0.86!6.20!IKZF1;;chr7:64838754..64838778,+!p1@ZNF92!0.85!61.41!ZNF92;;chr9:117160738..117160782,-!p2@AKNA!0.85!26.67!AKNA;;chr10:94449703..94449718,+!p1@HHEX!0.85!24.81!HHEX;;chr3:114866084..114866118,-!p2@ZBTB20!0.85!23.16!ZBTB20;;chr15:31619407..31619419,+!p9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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000842;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 43: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor1.CNhs10860.11231-116C7.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor1.CNhs10860.11231-116C7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor1.CNhs10860.11231-116C7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor1.CNhs10860.11231-116C7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Peripheral%2520Blood%2520Mononuclear%2520Cells%252c%2520donor1.CNhs10860.11231-116C7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11231-116C7 | |||
|is_a=EFO:0002091;;FF:0000135 | |||
|is_obsolete= | |||
|library_id=CNhs10860 | |||
|library_id_phase_based=2:CNhs10860 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11231 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10003.CCGTCC.11231 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11231 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10003.CCGTCC.11231 | |||
|name=Peripheral Blood Mononuclear Cells, donor1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs10860,LSID702,release008,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=SRhi10003,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0.48681009190657,0,0.095712151429431,0,0,0,0.0492784950520221,0.150306889650249,-0.127055242543265,-0.282403560576942,0,0,0,0.0816237948221813,0,0,0,0,0,0.209596525138408,0.150306889650249,0,0,-0.153323010348428,0,0,0,0,0.150306889650249,-0.0979578962680575,0,0,-0.132956589778862,0,0,0,0,0,0.0243347286246724,0,0,0,0.150306889650249,0,0,-0.317954060866147,0,0,0,0,0,0,0,0,0.0509384237122905,0,0,0,0,0,0,0.0816237948221813,-0.0153685664204238,0,0.261755686906388,0.112252897925311,0,0.406312622605576,0,0,0,0,0.209596525138408,0,0,0,1.01302950187906,0,0,0.388700729296098,0,0,0,0,0.0816237948221813,0,0,0.0388669093203882,0,0,-0.231082594662535,0,0,0,0.058963733052508,0.438456488901992,0.0408118974110906,0,0.154158406171268,0,0.443695658783047,-0.02251185856468,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.115588664035066,0.0816237948221813,0,0,-0.0562854122951422,-0.0585484871534357,0.0816237948221813,0,0,0,0,0 | |||
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| |||
|rna_box=116 | |||
|rna_catalog_number=3H100-10-10 | |||
|rna_concentration=1.286 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number=PBMC721 | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=C7 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=116C7 | |||
|rna_weight_ug=10 | |||
|rnaseq_library_id=SRhi10003.CCGTCC | |||
|sample_age=47 | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=mononuclear cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=3HBiomedical | |||
|sample_description= | |||
|sample_dev_stage=47 years old adult | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;8.19326404616708e-220!GO:0043227;membrane-bound organelle;1.35274910270471e-160!GO:0043231;intracellular membrane-bound organelle;2.32845973637809e-160!GO:0043226;organelle;1.90805055528786e-149!GO:0043229;intracellular organelle;7.7968001029113e-149!GO:0005737;cytoplasm;5.66838024129039e-123!GO:0005634;nucleus;3.12581743422754e-88!GO:0043170;macromolecule metabolic process;1.5127649258379e-84!GO:0044422;organelle part;1.52102901473864e-84!GO:0044446;intracellular organelle part;4.5728226946334e-83!GO:0044237;cellular metabolic process;8.63597166153607e-81!GO:0044238;primary metabolic process;1.21830338716816e-79!GO:0044444;cytoplasmic part;4.74210899132015e-76!GO:0032991;macromolecular complex;1.83889992098026e-70!GO:0005515;protein binding;6.48231889036674e-70!GO:0044428;nuclear part;2.96095087480369e-68!GO:0003723;RNA binding;3.38825660118226e-66!GO:0043283;biopolymer metabolic process;2.87977874066357e-60!GO:0030529;ribonucleoprotein complex;1.89658687957399e-57!GO:0010467;gene expression;1.24442430393908e-52!GO:0043233;organelle lumen;1.49381026337626e-52!GO:0031974;membrane-enclosed lumen;1.49381026337626e-52!GO:0019538;protein metabolic process;6.54927124175941e-46!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.38619668123255e-45!GO:0033036;macromolecule localization;3.40131821977099e-45!GO:0015031;protein transport;1.46616751011934e-43!GO:0044267;cellular protein metabolic process;5.50012318203062e-43!GO:0031981;nuclear lumen;8.36309202724991e-43!GO:0044260;cellular macromolecule metabolic process;2.13478327900771e-42!GO:0045184;establishment of protein localization;2.1453627101076e-42!GO:0006412;translation;8.45979245910094e-42!GO:0008104;protein localization;3.74170108080866e-41!GO:0006396;RNA processing;1.37042877437245e-40!GO:0016071;mRNA metabolic process;1.49147925231854e-38!GO:0043234;protein complex;4.26693235126517e-36!GO:0008380;RNA splicing;5.92481758032962e-34!GO:0003676;nucleic acid binding;1.4635928843787e-32!GO:0006397;mRNA processing;3.97297373430314e-32!GO:0005829;cytosol;6.73372829384508e-31!GO:0016043;cellular component organization and biogenesis;6.74787055565378e-31!GO:0046907;intracellular transport;4.65900716117385e-30!GO:0016070;RNA metabolic process;8.16605313958325e-30!GO:0005739;mitochondrion;8.18404851631761e-30!GO:0031090;organelle membrane;9.08151422457077e-30!GO:0009059;macromolecule biosynthetic process;1.4587698757804e-29!GO:0006886;intracellular protein transport;3.27456303562975e-29!GO:0005840;ribosome;2.85004813452685e-28!GO:0005654;nucleoplasm;4.74425309395492e-28!GO:0031967;organelle envelope;2.60716856851055e-27!GO:0006915;apoptosis;3.9611476743101e-27!GO:0012501;programmed cell death;4.70621517914847e-27!GO:0031975;envelope;5.17582927306849e-27!GO:0008219;cell death;5.67791713505516e-26!GO:0016265;death;5.67791713505516e-26!GO:0000166;nucleotide binding;1.71886906099452e-25!GO:0005681;spliceosome;2.69605311034822e-25!GO:0003735;structural constituent of ribosome;8.77405752040749e-25!GO:0065003;macromolecular complex assembly;1.48913743027089e-24!GO:0051641;cellular localization;2.03589721768933e-23!GO:0051649;establishment of cellular localization;2.17023661283222e-23!GO:0044249;cellular biosynthetic process;4.88086313850477e-23!GO:0044451;nucleoplasm part;5.4718214778507e-23!GO:0033279;ribosomal subunit;6.20816832916455e-23!GO:0044429;mitochondrial part;3.40388898744817e-22!GO:0009058;biosynthetic process;5.75814490522611e-22!GO:0043412;biopolymer modification;6.78533202369216e-22!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.18270347228133e-21!GO:0006259;DNA metabolic process;1.20852635868776e-21!GO:0006512;ubiquitin cycle;1.2442897707232e-21!GO:0022607;cellular component assembly;1.82723644579097e-21!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.63395877988647e-21!GO:0050794;regulation of cellular process;3.20589759139537e-21!GO:0008134;transcription factor binding;3.7829872818598e-21!GO:0044445;cytosolic part;2.10232211288805e-20!GO:0006464;protein modification process;1.29955002935588e-19!GO:0043687;post-translational protein modification;1.66085114408725e-19!GO:0032553;ribonucleotide binding;8.51888125431447e-19!GO:0032555;purine ribonucleotide binding;8.51888125431447e-19!GO:0006996;organelle organization and biogenesis;1.32989575435455e-18!GO:0042981;regulation of apoptosis;1.56153896600187e-18!GO:0044265;cellular macromolecule catabolic process;3.3503643562603e-18!GO:0043067;regulation of programmed cell death;3.39702656949375e-18!GO:0017076;purine nucleotide binding;9.62674008385014e-18!GO:0051603;proteolysis involved in cellular protein catabolic process;1.78389996129799e-17!GO:0019941;modification-dependent protein catabolic process;1.8186612250245e-17!GO:0043632;modification-dependent macromolecule catabolic process;1.8186612250245e-17!GO:0016874;ligase activity;2.2212449019111e-17!GO:0006511;ubiquitin-dependent protein catabolic process;2.47909574362633e-17!GO:0016462;pyrophosphatase activity;3.00934174349083e-17!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.17031758596904e-17!GO:0017111;nucleoside-triphosphatase activity;3.34924641811634e-17!GO:0016817;hydrolase activity, acting on acid anhydrides;4.17856918166551e-17!GO:0044257;cellular protein catabolic process;4.79746756795964e-17!GO:0016604;nuclear body;7.68561797784834e-17!GO:0006913;nucleocytoplasmic transport;1.00079476641477e-16!GO:0006605;protein targeting;1.94128074764857e-16!GO:0051169;nuclear transport;2.48884099625919e-16!GO:0050789;regulation of biological process;5.32434203895877e-16!GO:0005740;mitochondrial envelope;1.29394890842536e-15!GO:0022618;protein-RNA complex assembly;1.30316292994009e-15!GO:0031966;mitochondrial membrane;2.61007657895783e-15!GO:0043285;biopolymer catabolic process;3.1557013166914e-15!GO:0019222;regulation of metabolic process;4.71536091902597e-15!GO:0005524;ATP binding;5.58251504299641e-15!GO:0016192;vesicle-mediated transport;6.25925471065272e-15!GO:0005730;nucleolus;7.69780416372193e-15!GO:0032559;adenyl ribonucleotide binding;1.10469400597657e-14!GO:0019866;organelle inner membrane;1.43335652395774e-14!GO:0002376;immune system process;1.67057654306587e-14!GO:0016607;nuclear speck;1.84660810153261e-14!GO:0006119;oxidative phosphorylation;1.96822856101609e-14!GO:0048523;negative regulation of cellular process;6.09760789462959e-14!GO:0006793;phosphorus metabolic process;9.71668036160079e-14!GO:0006796;phosphate metabolic process;9.71668036160079e-14!GO:0030554;adenyl nucleotide binding;1.44177160861881e-13!GO:0007243;protein kinase cascade;2.3701944332885e-13!GO:0003712;transcription cofactor activity;2.93436292905683e-13!GO:0009057;macromolecule catabolic process;4.4591777207115e-13!GO:0048770;pigment granule;4.56418488393155e-13!GO:0042470;melanosome;4.56418488393155e-13!GO:0008135;translation factor activity, nucleic acid binding;7.21825760915589e-13!GO:0005635;nuclear envelope;1.00824918684311e-12!GO:0065007;biological regulation;1.21549152670818e-12!GO:0005743;mitochondrial inner membrane;1.76909101035793e-12!GO:0031323;regulation of cellular metabolic process;1.8669261028188e-12!GO:0007242;intracellular signaling cascade;1.93836500597863e-12!GO:0043228;non-membrane-bound organelle;2.71920192738688e-12!GO:0043232;intracellular non-membrane-bound organelle;2.71920192738688e-12!GO:0006366;transcription from RNA polymerase II promoter;2.83403664698327e-12!GO:0006325;establishment and/or maintenance of chromatin architecture;4.27921046492024e-12!GO:0044248;cellular catabolic process;5.42282166115057e-12!GO:0015934;large ribosomal subunit;5.73703081802745e-12!GO:0016310;phosphorylation;6.03823293866712e-12!GO:0015935;small ribosomal subunit;7.66925461466853e-12!GO:0030163;protein catabolic process;7.77331533876864e-12!GO:0000398;nuclear mRNA splicing, via spliceosome;9.69072606581111e-12!GO:0000375;RNA splicing, via transesterification reactions;9.69072606581111e-12!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;9.69072606581111e-12!GO:0051246;regulation of protein metabolic process;1.06273008926639e-11!GO:0012505;endomembrane system;1.13811224535342e-11!GO:0048519;negative regulation of biological process;1.27756079184316e-11!GO:0031965;nuclear membrane;1.5426018899235e-11!GO:0006323;DNA packaging;1.89988600061808e-11!GO:0007049;cell cycle;2.05758035711045e-11!GO:0051276;chromosome organization and biogenesis;2.59690237854571e-11!GO:0006974;response to DNA damage stimulus;2.62365661272429e-11!GO:0008639;small protein conjugating enzyme activity;2.73731615556304e-11!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.08041051349261e-11!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;3.42606943288352e-11!GO:0007249;I-kappaB kinase/NF-kappaB cascade;3.59479296260548e-11!GO:0006457;protein folding;3.89226669756483e-11!GO:0004842;ubiquitin-protein ligase activity;4.38871601121468e-11!GO:0065009;regulation of a molecular function;5.023916608155e-11!GO:0017038;protein import;5.35261139776019e-11!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.56373174567178e-11!GO:0016568;chromatin modification;9.55143078833302e-11!GO:0043069;negative regulation of programmed cell death;1.25674408842605e-10!GO:0019787;small conjugating protein ligase activity;1.30840207561724e-10!GO:0005768;endosome;1.59865679497899e-10!GO:0004386;helicase activity;1.70906260650682e-10!GO:0010468;regulation of gene expression;1.8082728148141e-10!GO:0043066;negative regulation of apoptosis;1.82921366433187e-10!GO:0006446;regulation of translational initiation;1.87515604875162e-10!GO:0000502;proteasome complex (sensu Eukaryota);1.96634681382165e-10!GO:0006955;immune response;2.05967405074199e-10!GO:0016887;ATPase activity;2.07981880091673e-10!GO:0005794;Golgi apparatus;2.27407259304439e-10!GO:0044455;mitochondrial membrane part;2.49814459666345e-10!GO:0042623;ATPase activity, coupled;3.60184354250057e-10!GO:0006916;anti-apoptosis;4.7966496975841e-10!GO:0006350;transcription;5.37300502534571e-10!GO:0003743;translation initiation factor activity;6.14756564739232e-10!GO:0044453;nuclear membrane part;6.27217574672016e-10!GO:0048193;Golgi vesicle transport;6.29923004739896e-10!GO:0006413;translational initiation;7.39351375309269e-10!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;8.67919549854604e-10!GO:0050657;nucleic acid transport;9.98072603909805e-10!GO:0051236;establishment of RNA localization;9.98072603909805e-10!GO:0050658;RNA transport;9.98072603909805e-10!GO:0006403;RNA localization;1.23936370724154e-09!GO:0051170;nuclear import;1.44704562467745e-09!GO:0005773;vacuole;1.5690482128217e-09!GO:0006606;protein import into nucleus;1.80057213523441e-09!GO:0045321;leukocyte activation;2.58063232019482e-09!GO:0008026;ATP-dependent helicase activity;2.79846665279687e-09!GO:0031324;negative regulation of cellular metabolic process;3.02637794444834e-09!GO:0006417;regulation of translation;5.68408698532258e-09!GO:0005746;mitochondrial respiratory chain;5.78463605843807e-09!GO:0003713;transcription coactivator activity;5.89655971348999e-09!GO:0016563;transcription activator activity;6.49851899680344e-09!GO:0046649;lymphocyte activation;6.7941717981229e-09!GO:0000323;lytic vacuole;7.74856331180763e-09!GO:0005764;lysosome;7.74856331180763e-09!GO:0031980;mitochondrial lumen;7.91626235644156e-09!GO:0005759;mitochondrial matrix;7.91626235644156e-09!GO:0006281;DNA repair;8.12149592851749e-09!GO:0019899;enzyme binding;9.38112251229314e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;9.91051454799243e-09!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.11169066316793e-08!GO:0051726;regulation of cell cycle;1.43102614851636e-08!GO:0016564;transcription repressor activity;1.71394594297421e-08!GO:0016881;acid-amino acid ligase activity;1.82861295499568e-08!GO:0005643;nuclear pore;1.85763959843253e-08!GO:0048522;positive regulation of cellular process;2.05024012545104e-08!GO:0050136;NADH dehydrogenase (quinone) activity;2.16430049653164e-08!GO:0003954;NADH dehydrogenase activity;2.16430049653164e-08!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.16430049653164e-08!GO:0000074;regulation of progression through cell cycle;2.16992872423055e-08!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;3.08387852332643e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;3.5447390850125e-08!GO:0019829;cation-transporting ATPase activity;4.51353106433683e-08!GO:0043065;positive regulation of apoptosis;4.51353106433683e-08!GO:0051082;unfolded protein binding;5.02246453343728e-08!GO:0051028;mRNA transport;5.16267085817582e-08!GO:0016787;hydrolase activity;6.94718094605765e-08!GO:0043068;positive regulation of programmed cell death;7.90389725971487e-08!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;8.16069304187389e-08!GO:0051186;cofactor metabolic process;1.13825346182844e-07!GO:0009892;negative regulation of metabolic process;1.14439050746915e-07!GO:0032446;protein modification by small protein conjugation;1.16234553399976e-07!GO:0006917;induction of apoptosis;1.20571966887945e-07!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.20571966887945e-07!GO:0031326;regulation of cellular biosynthetic process;1.25418124971159e-07!GO:0008565;protein transporter activity;1.39225592006981e-07!GO:0007264;small GTPase mediated signal transduction;1.55872081311823e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.58561967445403e-07!GO:0016481;negative regulation of transcription;1.74410603030417e-07!GO:0043566;structure-specific DNA binding;1.83973794399615e-07!GO:0032774;RNA biosynthetic process;1.9629869109618e-07!GO:0006351;transcription, DNA-dependent;2.08325521316619e-07!GO:0012502;induction of programmed cell death;2.08593490093608e-07!GO:0045449;regulation of transcription;2.21091470308172e-07!GO:0022402;cell cycle process;2.21091470308172e-07!GO:0006950;response to stress;2.47402061144599e-07!GO:0042775;organelle ATP synthesis coupled electron transport;2.51263551367808e-07!GO:0042773;ATP synthesis coupled electron transport;2.51263551367808e-07!GO:0016567;protein ubiquitination;2.63511159157554e-07!GO:0001775;cell activation;2.75138113838171e-07!GO:0042110;T cell activation;3.46637533935112e-07!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;3.56139872571992e-07!GO:0008270;zinc ion binding;3.62187583854581e-07!GO:0050790;regulation of catalytic activity;3.66162598215233e-07!GO:0009889;regulation of biosynthetic process;4.44385028197326e-07!GO:0005783;endoplasmic reticulum;4.50893017066533e-07!GO:0042254;ribosome biogenesis and assembly;4.54566133165581e-07!GO:0048518;positive regulation of biological process;5.26138042696987e-07!GO:0009259;ribonucleotide metabolic process;5.45815557571579e-07!GO:0006461;protein complex assembly;5.57208601633019e-07!GO:0045786;negative regulation of progression through cell cycle;5.78811174270538e-07!GO:0009615;response to virus;6.18761969006629e-07!GO:0009719;response to endogenous stimulus;6.26983352416658e-07!GO:0030964;NADH dehydrogenase complex (quinone);6.27150226858411e-07!GO:0045271;respiratory chain complex I;6.27150226858411e-07!GO:0005747;mitochondrial respiratory chain complex I;6.27150226858411e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;7.11884742139298e-07!GO:0005694;chromosome;8.3254391041428e-07!GO:0009967;positive regulation of signal transduction;8.32765397070008e-07!GO:0003697;single-stranded DNA binding;8.52181724123024e-07!GO:0060090;molecular adaptor activity;9.95847764575009e-07!GO:0005770;late endosome;1.02022824767712e-06!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.04925575981972e-06!GO:0015986;ATP synthesis coupled proton transport;1.08294445218596e-06!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.08294445218596e-06!GO:0001772;immunological synapse;1.19574195263215e-06!GO:0065002;intracellular protein transport across a membrane;1.28249666454562e-06!GO:0009260;ribonucleotide biosynthetic process;1.35098526230116e-06!GO:0046930;pore complex;1.4196229233441e-06!GO:0008047;enzyme activator activity;1.44128541868733e-06!GO:0009152;purine ribonucleotide biosynthetic process;1.66548812691578e-06!GO:0003924;GTPase activity;1.76759107832734e-06!GO:0009150;purine ribonucleotide metabolic process;1.94266352644392e-06!GO:0006333;chromatin assembly or disassembly;2.00032742651942e-06!GO:0006164;purine nucleotide biosynthetic process;2.00120475318823e-06!GO:0030695;GTPase regulator activity;2.08320104085782e-06!GO:0006163;purine nucleotide metabolic process;2.12908842807641e-06!GO:0009966;regulation of signal transduction;2.52979313276204e-06!GO:0005525;GTP binding;2.74636869801353e-06!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.56602897773151e-06!GO:0009056;catabolic process;4.02117188653233e-06!GO:0044440;endosomal part;4.5429942918657e-06!GO:0010008;endosome membrane;4.5429942918657e-06!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.57047603824628e-06!GO:0006732;coenzyme metabolic process;5.00469503218675e-06!GO:0000151;ubiquitin ligase complex;5.15440242966708e-06!GO:0065004;protein-DNA complex assembly;5.26523146478645e-06!GO:0015078;hydrogen ion transmembrane transporter activity;5.27941253720422e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;5.40031971877739e-06!GO:0030532;small nuclear ribonucleoprotein complex;5.42711860360717e-06!GO:0051168;nuclear export;5.46764952877789e-06!GO:0006355;regulation of transcription, DNA-dependent;6.72671628317958e-06!GO:0002757;immune response-activating signal transduction;6.96781987501727e-06!GO:0048475;coated membrane;7.23388439262956e-06!GO:0030117;membrane coat;7.23388439262956e-06!GO:0006401;RNA catabolic process;7.26923579988745e-06!GO:0016469;proton-transporting two-sector ATPase complex;7.26923579988745e-06!GO:0005793;ER-Golgi intermediate compartment;7.81155763421987e-06!GO:0002764;immune response-regulating signal transduction;8.98211905789313e-06!GO:0009060;aerobic respiration;9.28104965697463e-06!GO:0044432;endoplasmic reticulum part;9.35652137668201e-06!GO:0004674;protein serine/threonine kinase activity;1.02607436400965e-05!GO:0016740;transferase activity;1.0488064311373e-05!GO:0007265;Ras protein signal transduction;1.12431714900914e-05!GO:0006754;ATP biosynthetic process;1.15343988721791e-05!GO:0006753;nucleoside phosphate metabolic process;1.15343988721791e-05!GO:0044427;chromosomal part;1.37442678719723e-05!GO:0003714;transcription corepressor activity;1.40305565102846e-05!GO:0002429;immune response-activating cell surface receptor signaling pathway;1.49107861681232e-05!GO:0006888;ER to Golgi vesicle-mediated transport;1.49858360310484e-05!GO:0003724;RNA helicase activity;1.50771067128474e-05!GO:0030120;vesicle coat;1.52202205271901e-05!GO:0030662;coated vesicle membrane;1.52202205271901e-05!GO:0046034;ATP metabolic process;1.78222267152043e-05!GO:0009142;nucleoside triphosphate biosynthetic process;1.88417317761132e-05!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.88417317761132e-05!GO:0002768;immune response-regulating cell surface receptor signaling pathway;1.9178180991148e-05!GO:0009199;ribonucleoside triphosphate metabolic process;1.95077731743022e-05!GO:0000245;spliceosome assembly;2.2130438111016e-05!GO:0000785;chromatin;2.49948500294504e-05!GO:0008632;apoptotic program;2.6476188945022e-05!GO:0005839;proteasome core complex (sensu Eukaryota);2.6476188945022e-05!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.75901070567598e-05!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.75901070567598e-05!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.81636524665914e-05!GO:0009144;purine nucleoside triphosphate metabolic process;2.81636524665914e-05!GO:0006613;cotranslational protein targeting to membrane;3.09065330876237e-05!GO:0005070;SH3/SH2 adaptor activity;3.22196263602182e-05!GO:0048468;cell development;3.29743459116344e-05!GO:0009141;nucleoside triphosphate metabolic process;3.4126467591917e-05!GO:0032561;guanyl ribonucleotide binding;3.46761932820116e-05!GO:0019001;guanyl nucleotide binding;3.46761932820116e-05!GO:0031252;leading edge;3.80918263414099e-05!GO:0051336;regulation of hydrolase activity;3.85360326699651e-05!GO:0045259;proton-transporting ATP synthase complex;4.02252775234093e-05!GO:0005096;GTPase activator activity;4.12278699341038e-05!GO:0005083;small GTPase regulator activity;4.18947636003351e-05!GO:0005813;centrosome;4.46281734580787e-05!GO:0005761;mitochondrial ribosome;4.83664225576748e-05!GO:0000313;organellar ribosome;4.83664225576748e-05!GO:0030097;hemopoiesis;4.85015310660968e-05!GO:0016044;membrane organization and biogenesis;5.20031270511118e-05!GO:0046914;transition metal ion binding;5.25095434605783e-05!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.61131165894778e-05!GO:0008234;cysteine-type peptidase activity;6.05323118869662e-05!GO:0006402;mRNA catabolic process;6.24347474281357e-05!GO:0016363;nuclear matrix;6.2557873059813e-05!GO:0045892;negative regulation of transcription, DNA-dependent;6.48973158637484e-05!GO:0016072;rRNA metabolic process;6.71388376171411e-05!GO:0006364;rRNA processing;6.85467888518866e-05!GO:0005774;vacuolar membrane;7.1834263519593e-05!GO:0004298;threonine endopeptidase activity;7.52897643717837e-05!GO:0006399;tRNA metabolic process;7.52897643717837e-05!GO:0042101;T cell receptor complex;8.09842685576036e-05!GO:0045333;cellular respiration;8.30148468002005e-05!GO:0005789;endoplasmic reticulum membrane;8.41829246664325e-05!GO:0051251;positive regulation of lymphocyte activation;8.51636778729059e-05!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;8.76254972847182e-05!GO:0004812;aminoacyl-tRNA ligase activity;8.76254972847182e-05!GO:0016875;ligase activity, forming carbon-oxygen bonds;8.76254972847182e-05!GO:0001816;cytokine production;9.22168867348859e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000118555055110808!GO:0016197;endosome transport;0.000130492924330414!GO:0009893;positive regulation of metabolic process;0.000134711646885988!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000142110285627204!GO:0051188;cofactor biosynthetic process;0.000153523473506692!GO:0006099;tricarboxylic acid cycle;0.000163738481910821!GO:0046356;acetyl-CoA catabolic process;0.000163738481910821!GO:0043038;amino acid activation;0.00017211450955885!GO:0006418;tRNA aminoacylation for protein translation;0.00017211450955885!GO:0043039;tRNA aminoacylation;0.00017211450955885!GO:0008186;RNA-dependent ATPase activity;0.000185172566335058!GO:0005057;receptor signaling protein activity;0.000189028831208858!GO:0016301;kinase activity;0.000211207238953089!GO:0005815;microtubule organizing center;0.000229968782681235!GO:0005765;lysosomal membrane;0.000239742429188631!GO:0046822;regulation of nucleocytoplasmic transport;0.000251199857524237!GO:0044437;vacuolar part;0.000262545366635527!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.000265735891772361!GO:0005885;Arp2/3 protein complex;0.000269142705839692!GO:0050851;antigen receptor-mediated signaling pathway;0.000290902773995176!GO:0001819;positive regulation of cytokine production;0.000300902942188129!GO:0031982;vesicle;0.000310003695546453!GO:0032940;secretion by cell;0.00032477119098933!GO:0002520;immune system development;0.000331747468225445!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000339957891979795!GO:0015399;primary active transmembrane transporter activity;0.000339957891979795!GO:0005769;early endosome;0.000348783165067661!GO:0006468;protein amino acid phosphorylation;0.000374964542488614!GO:0044431;Golgi apparatus part;0.00038278971456154!GO:0005667;transcription factor complex;0.00038278971456154!GO:0006612;protein targeting to membrane;0.000396499227398237!GO:0051090;regulation of transcription factor activity;0.000406611147719593!GO:0005798;Golgi-associated vesicle;0.000408041161924087!GO:0031902;late endosome membrane;0.000408287514115967!GO:0006084;acetyl-CoA metabolic process;0.000410642855214418!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000416622909962578!GO:0042113;B cell activation;0.000451227240328528!GO:0008654;phospholipid biosynthetic process;0.000462960487512708!GO:0016779;nucleotidyltransferase activity;0.00048630882882156!GO:0006260;DNA replication;0.000488191357192571!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000489346951964626!GO:0009108;coenzyme biosynthetic process;0.000505324491861302!GO:0003690;double-stranded DNA binding;0.000514313357525799!GO:0051427;hormone receptor binding;0.000517380376681039!GO:0003729;mRNA binding;0.000524327287497351!GO:0046983;protein dimerization activity;0.0005286655158303!GO:0043087;regulation of GTPase activity;0.00053399199839372!GO:0004004;ATP-dependent RNA helicase activity;0.000549388329285777!GO:0051187;cofactor catabolic process;0.000550667369603283!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000556767883694667!GO:0001817;regulation of cytokine production;0.000593423600189987!GO:0000278;mitotic cell cycle;0.000657816930599092!GO:0045941;positive regulation of transcription;0.000687166365387228!GO:0003677;DNA binding;0.000709983518483085!GO:0006607;NLS-bearing substrate import into nucleus;0.000789291799031575!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000854353540281005!GO:0051223;regulation of protein transport;0.000878586869670902!GO:0022415;viral reproductive process;0.000886104304639274!GO:0002521;leukocyte differentiation;0.000891721517510257!GO:0035257;nuclear hormone receptor binding;0.000916986327414555!GO:0045893;positive regulation of transcription, DNA-dependent;0.000924652084224143!GO:0006752;group transfer coenzyme metabolic process;0.000931378077667503!GO:0031325;positive regulation of cellular metabolic process;0.000987279428504654!GO:0031410;cytoplasmic vesicle;0.000998786070017395!GO:0050865;regulation of cell activation;0.00101959348747336!GO:0009055;electron carrier activity;0.00103486719419961!GO:0043623;cellular protein complex assembly;0.00103999332100048!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00104523270974021!GO:0009109;coenzyme catabolic process;0.0010536943012423!GO:0004715;non-membrane spanning protein tyrosine kinase activity;0.00106839999323235!GO:0007050;cell cycle arrest;0.00108204332994829!GO:0051249;regulation of lymphocyte activation;0.00109798622377741!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00120738167590125!GO:0006611;protein export from nucleus;0.00127125423817347!GO:0006310;DNA recombination;0.00127125423817347!GO:0030384;phosphoinositide metabolic process;0.00128600584238305!GO:0045045;secretory pathway;0.00128675985998786!GO:0043492;ATPase activity, coupled to movement of substances;0.00129661726166369!GO:0048534;hemopoietic or lymphoid organ development;0.00131445931686162!GO:0051338;regulation of transferase activity;0.00132822827614776!GO:0007005;mitochondrion organization and biogenesis;0.00137657279790866!GO:0003725;double-stranded RNA binding;0.00138012562823738!GO:0031988;membrane-bound vesicle;0.00148658240306466!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00148963886868!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00154745605689779!GO:0005741;mitochondrial outer membrane;0.00179735001090018!GO:0018193;peptidyl-amino acid modification;0.00192734386853294!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00194098108552533!GO:0030658;transport vesicle membrane;0.00195797478896233!GO:0043549;regulation of kinase activity;0.00198163405105778!GO:0006650;glycerophospholipid metabolic process;0.00204951612176608!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.00217172591116581!GO:0042802;identical protein binding;0.0022671419659248!GO:0019783;small conjugating protein-specific protease activity;0.00230532496904041!GO:0019867;outer membrane;0.00237151491154758!GO:0043021;ribonucleoprotein binding;0.00243252996598729!GO:0032318;regulation of Ras GTPase activity;0.00250249584327848!GO:0050870;positive regulation of T cell activation;0.00256539255989197!GO:0001726;ruffle;0.00260987491176321!GO:0031968;organelle outer membrane;0.00263305458103709!GO:0006352;transcription initiation;0.00266736662875498!GO:0030258;lipid modification;0.00268458178888605!GO:0048471;perinuclear region of cytoplasm;0.00268858527619495!GO:0019221;cytokine and chemokine mediated signaling pathway;0.00273191200795756!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00279385412458367!GO:0009607;response to biotic stimulus;0.00286550418177071!GO:0051252;regulation of RNA metabolic process;0.00291006207465189!GO:0030098;lymphocyte differentiation;0.00301403772722783!GO:0016251;general RNA polymerase II transcription factor activity;0.00301403772722783!GO:0006334;nucleosome assembly;0.00301403772722783!GO:0007034;vacuolar transport;0.00301403772722783!GO:0004843;ubiquitin-specific protease activity;0.0030535472611579!GO:0006818;hydrogen transport;0.00305479880013876!GO:0030118;clathrin coat;0.00314213495077173!GO:0005099;Ras GTPase activator activity;0.00314213495077173!GO:0033157;regulation of intracellular protein transport;0.00314213495077173!GO:0042306;regulation of protein import into nucleus;0.00314213495077173!GO:0031497;chromatin assembly;0.00315131581657561!GO:0016023;cytoplasmic membrane-bound vesicle;0.00324035364833707!GO:0015992;proton transport;0.0033443866693785!GO:0009117;nucleotide metabolic process;0.00334804509065475!GO:0006891;intra-Golgi vesicle-mediated transport;0.00345077948019532!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00359116668481874!GO:0006919;caspase activation;0.00359116668481874!GO:0031625;ubiquitin protein ligase binding;0.00365927034633483!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00374377608576848!GO:0005637;nuclear inner membrane;0.00377892050570791!GO:0030217;T cell differentiation;0.0038564954124407!GO:0051098;regulation of binding;0.0039296007154483!GO:0045859;regulation of protein kinase activity;0.00412520396489142!GO:0043280;positive regulation of caspase activity;0.00427711201947458!GO:0043281;regulation of caspase activity;0.00441243510277845!GO:0004221;ubiquitin thiolesterase activity;0.0044471017782384!GO:0051092;activation of NF-kappaB transcription factor;0.00453791435323879!GO:0030660;Golgi-associated vesicle membrane;0.00460348018586502!GO:0006405;RNA export from nucleus;0.0050795896817855!GO:0050871;positive regulation of B cell activation;0.00512831256279496!GO:0030099;myeloid cell differentiation;0.0053251738063216!GO:0016584;nucleosome positioning;0.00538834777473415!GO:0047485;protein N-terminus binding;0.0053887189411174!GO:0002252;immune effector process;0.0055985748141749!GO:0016791;phosphoric monoester hydrolase activity;0.00560384967595796!GO:0045637;regulation of myeloid cell differentiation;0.00561398890009467!GO:0006897;endocytosis;0.00561398890009467!GO:0010324;membrane invagination;0.00561398890009467!GO:0015630;microtubule cytoskeleton;0.00576991488034381!GO:0050863;regulation of T cell activation;0.0059793524614853!GO:0043488;regulation of mRNA stability;0.00609240223468073!GO:0043487;regulation of RNA stability;0.00609240223468073!GO:0008287;protein serine/threonine phosphatase complex;0.00611168783651773!GO:0015631;tubulin binding;0.00613449356566355!GO:0000139;Golgi membrane;0.0064728680112296!GO:0016311;dephosphorylation;0.00692678409774207!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00692678409774207!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00692678409774207!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00692678409774207!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00714749189812953!GO:0031072;heat shock protein binding;0.00714749189812953!GO:0002440;production of molecular mediator of immune response;0.00715491638230252!GO:0008624;induction of apoptosis by extracellular signals;0.00715491638230252!GO:0017091;AU-rich element binding;0.00715491638230252!GO:0050779;RNA destabilization;0.00715491638230252!GO:0000289;poly(A) tail shortening;0.00715491638230252!GO:0030518;steroid hormone receptor signaling pathway;0.00733050926356634!GO:0005048;signal sequence binding;0.00740370498384427!GO:0048500;signal recognition particle;0.00746033310202741!GO:0019904;protein domain specific binding;0.00759446656419345!GO:0045792;negative regulation of cell size;0.0075951099204858!GO:0042287;MHC protein binding;0.00762790758968052!GO:0000209;protein polyubiquitination;0.0079649624404665!GO:0043433;negative regulation of transcription factor activity;0.00807104356998879!GO:0042990;regulation of transcription factor import into nucleus;0.00822005667700542!GO:0042991;transcription factor import into nucleus;0.00822005667700542!GO:0005669;transcription factor TFIID complex;0.00827774874454416!GO:0006414;translational elongation;0.00834128255246262!GO:0003746;translation elongation factor activity;0.00854025611143091!GO:0019901;protein kinase binding;0.00857361486443607!GO:0046489;phosphoinositide biosynthetic process;0.00857361486443607!GO:0002443;leukocyte mediated immunity;0.00912349523112214!GO:0004177;aminopeptidase activity;0.00916096118885986!GO:0030218;erythrocyte differentiation;0.00929165340844942!GO:0004722;protein serine/threonine phosphatase activity;0.00931300062449788!GO:0008139;nuclear localization sequence binding;0.00985447664877127!GO:0003711;transcription elongation regulator activity;0.00997058690958998!GO:0030308;negative regulation of cell growth;0.0101247108681691!GO:0045058;T cell selection;0.0101247108681691!GO:0000118;histone deacetylase complex;0.0103137285313452!GO:0002274;myeloid leukocyte activation;0.01033353786342!GO:0005684;U2-dependent spliceosome;0.0105787775645685!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0106832492511553!GO:0045047;protein targeting to ER;0.0106832492511553!GO:0030041;actin filament polymerization;0.0107642605870201!GO:0006338;chromatin remodeling;0.01086993069166!GO:0030674;protein binding, bridging;0.01086993069166!GO:0033116;ER-Golgi intermediate compartment membrane;0.0110539931655821!GO:0006672;ceramide metabolic process;0.0115838725994645!GO:0003682;chromatin binding;0.0115838725994645!GO:0051049;regulation of transport;0.0116915245791129!GO:0006383;transcription from RNA polymerase III promoter;0.0118200293439447!GO:0022890;inorganic cation transmembrane transporter activity;0.0119602692871784!GO:0030867;rough endoplasmic reticulum membrane;0.0121549581756566!GO:0008629;induction of apoptosis by intracellular signals;0.012230326159757!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.012347108731589!GO:0002819;regulation of adaptive immune response;0.012347108731589!GO:0046474;glycerophospholipid biosynthetic process;0.0123866510345789!GO:0030521;androgen receptor signaling pathway;0.0129383212290462!GO:0045603;positive regulation of endothelial cell differentiation;0.0129621342291026!GO:0051091;positive regulation of transcription factor activity;0.0129711561311639!GO:0046467;membrane lipid biosynthetic process;0.0130883813715013!GO:0043300;regulation of leukocyte degranulation;0.0132101136456069!GO:0006376;mRNA splice site selection;0.0133008772376439!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0133008772376439!GO:0008312;7S RNA binding;0.01345032485662!GO:0030127;COPII vesicle coat;0.0134659735467097!GO:0012507;ER to Golgi transport vesicle membrane;0.0134659735467097!GO:0007259;JAK-STAT cascade;0.0136305851055906!GO:0033673;negative regulation of kinase activity;0.0136314750151231!GO:0006469;negative regulation of protein kinase activity;0.0136314750151231!GO:0007041;lysosomal transport;0.0137041853868469!GO:0045576;mast cell activation;0.0138314432251791!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.0138981679159165!GO:0008017;microtubule binding;0.0144318706460908!GO:0046966;thyroid hormone receptor binding;0.0148775464157391!GO:0006984;ER-nuclear signaling pathway;0.0149432607622825!GO:0043299;leukocyte degranulation;0.0149432607622825!GO:0050857;positive regulation of antigen receptor-mediated signaling pathway;0.0150459525005371!GO:0030036;actin cytoskeleton organization and biogenesis;0.0150459525005371!GO:0051329;interphase of mitotic cell cycle;0.0151914160307648!GO:0046578;regulation of Ras protein signal transduction;0.0153263948171976!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0153719952757084!GO:0006261;DNA-dependent DNA replication;0.0154750763215356!GO:0004185;serine carboxypeptidase activity;0.0154953131053218!GO:0019220;regulation of phosphate metabolic process;0.0157966221250456!GO:0051174;regulation of phosphorus metabolic process;0.0157966221250456!GO:0016788;hydrolase activity, acting on ester bonds;0.01585184130976!GO:0004672;protein kinase activity;0.0158561711693962!GO:0046519;sphingoid metabolic process;0.0160012756075119!GO:0006643;membrane lipid metabolic process;0.0160174949568914!GO:0003678;DNA helicase activity;0.016189922627738!GO:0030119;AP-type membrane coat adaptor complex;0.016566221593585!GO:0045646;regulation of erythrocyte differentiation;0.016769168043673!GO:0048487;beta-tubulin binding;0.0174528676613228!GO:0051056;regulation of small GTPase mediated signal transduction;0.0176641224697006!GO:0003899;DNA-directed RNA polymerase activity;0.0177204019513728!GO:0019079;viral genome replication;0.0177439800207448!GO:0001667;ameboidal cell migration;0.0179783026122827!GO:0032027;myosin light chain binding;0.0179783026122827!GO:0030131;clathrin adaptor complex;0.0182047878495155!GO:0051235;maintenance of localization;0.0182240077143131!GO:0046854;phosphoinositide phosphorylation;0.0182701130350852!GO:0004197;cysteine-type endopeptidase activity;0.0182701130350852!GO:0019900;kinase binding;0.0184441169604768!GO:0051325;interphase;0.0184795272836251!GO:0051348;negative regulation of transferase activity;0.0186477135627051!GO:0033367;protein localization in mast cell secretory granule;0.0186477135627051!GO:0033365;protein localization in organelle;0.0186477135627051!GO:0033371;T cell secretory granule organization and biogenesis;0.0186477135627051!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0186477135627051!GO:0033375;protease localization in T cell secretory granule;0.0186477135627051!GO:0042629;mast cell granule;0.0186477135627051!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0186477135627051!GO:0033364;mast cell secretory granule organization and biogenesis;0.0186477135627051!GO:0033380;granzyme B localization in T cell secretory granule;0.0186477135627051!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0186477135627051!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0186477135627051!GO:0033368;protease localization in mast cell secretory granule;0.0186477135627051!GO:0033366;protein localization in secretory granule;0.0186477135627051!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0186477135627051!GO:0033374;protein localization in T cell secretory granule;0.0186477135627051!GO:0030134;ER to Golgi transport vesicle;0.0186521927361899!GO:0045926;negative regulation of growth;0.0186573252887505!GO:0019058;viral infectious cycle;0.0186715131438947!GO:0003702;RNA polymerase II transcription factor activity;0.0186812722330739!GO:0042108;positive regulation of cytokine biosynthetic process;0.0188905261972066!GO:0016585;chromatin remodeling complex;0.0189104150971932!GO:0051059;NF-kappaB binding;0.019219644829413!GO:0008097;5S rRNA binding;0.0195895283528253!GO:0031098;stress-activated protein kinase signaling pathway;0.0196335035977803!GO:0051789;response to protein stimulus;0.0198335960351368!GO:0006986;response to unfolded protein;0.0198335960351368!GO:0030522;intracellular receptor-mediated signaling pathway;0.0199831498299482!GO:0016790;thiolester hydrolase activity;0.0199891207547998!GO:0005791;rough endoplasmic reticulum;0.0202330846267167!GO:0032386;regulation of intracellular transport;0.0202731107500609!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.020661246036801!GO:0032200;telomere organization and biogenesis;0.0209193531555578!GO:0000723;telomere maintenance;0.0209193531555578!GO:0050811;GABA receptor binding;0.02161671335663!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0216303300262711!GO:0015923;mannosidase activity;0.021921903912753!GO:0001516;prostaglandin biosynthetic process;0.021921903912753!GO:0046457;prostanoid biosynthetic process;0.021921903912753!GO:0043414;biopolymer methylation;0.0221909425654668!GO:0031901;early endosome membrane;0.0228770974593471!GO:0043681;protein import into mitochondrion;0.0228824728917519!GO:0030027;lamellipodium;0.0238213287416721!GO:0000082;G1/S transition of mitotic cell cycle;0.0238238150098248!GO:0050900;leukocyte migration;0.0239171483632919!GO:0022411;cellular component disassembly;0.0240285699212266!GO:0019210;kinase inhibitor activity;0.0243419173605314!GO:0051345;positive regulation of hydrolase activity;0.0246036418384636!GO:0045454;cell redox homeostasis;0.0248958676438771!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0253850508640886!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0253850508640886!GO:0005521;lamin binding;0.0255401253300983!GO:0051051;negative regulation of transport;0.0257097145314476!GO:0045069;regulation of viral genome replication;0.0260109605333071!GO:0006302;double-strand break repair;0.0263774917262686!GO:0019883;antigen processing and presentation of endogenous antigen;0.0271444357934704!GO:0046834;lipid phosphorylation;0.0273271335944797!GO:0006968;cellular defense response;0.0279165379264386!GO:0005762;mitochondrial large ribosomal subunit;0.0280720805620216!GO:0000315;organellar large ribosomal subunit;0.0280720805620216!GO:0022403;cell cycle phase;0.0283001868517766!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0283001868517766!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0284664576821667!GO:0043085;positive regulation of catalytic activity;0.0285149100399445!GO:0004860;protein kinase inhibitor activity;0.0287518723142327!GO:0008637;apoptotic mitochondrial changes;0.0293182949123113!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0293508608663047!GO:0007040;lysosome organization and biogenesis;0.0297814052704961!GO:0006914;autophagy;0.0298348447428807!GO:0019882;antigen processing and presentation;0.0298348447428807!GO:0022406;membrane docking;0.0298476016804506!GO:0048278;vesicle docking;0.0298476016804506!GO:0050864;regulation of B cell activation;0.0301304680679357!GO:0006289;nucleotide-excision repair;0.030359520695225!GO:0043621;protein self-association;0.0304622515470958!GO:0032763;regulation of mast cell cytokine production;0.0307091240162689!GO:0032762;mast cell cytokine production;0.0307091240162689!GO:0045086;positive regulation of interleukin-2 biosynthetic process;0.031383049052151!GO:0042608;T cell receptor binding;0.0315307964474686!GO:0004218;cathepsin S activity;0.031651723117576!GO:0050852;T cell receptor signaling pathway;0.0316559178931946!GO:0016605;PML body;0.0317964998808962!GO:0016505;apoptotic protease activator activity;0.0320817518058301!GO:0051539;4 iron, 4 sulfur cluster binding;0.0325107172917748!GO:0043022;ribosome binding;0.0325107172917748!GO:0000059;protein import into nucleus, docking;0.0325107172917748!GO:0006904;vesicle docking during exocytosis;0.0325107172917748!GO:0000287;magnesium ion binding;0.0338048999095838!GO:0000339;RNA cap binding;0.0341483844828017!GO:0030125;clathrin vesicle coat;0.0341615883579145!GO:0030665;clathrin coated vesicle membrane;0.0341615883579145!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0345897941750795!GO:0006595;polyamine metabolic process;0.0349801040265272!GO:0007254;JNK cascade;0.0349801040265272!GO:0002444;myeloid leukocyte mediated immunity;0.0350051091652067!GO:0002467;germinal center formation;0.0350862150615893!GO:0002378;immunoglobulin biosynthetic process;0.0350862150615893!GO:0001911;negative regulation of leukocyte mediated cytotoxicity;0.0350862150615893!GO:0001915;negative regulation of T cell mediated cytotoxicity;0.0350862150615893!GO:0030176;integral to endoplasmic reticulum membrane;0.0356200462283385!GO:0004527;exonuclease activity;0.036022952206106!GO:0040029;regulation of gene expression, epigenetic;0.0362956981653041!GO:0006213;pyrimidine nucleoside metabolic process;0.0364418902181854!GO:0050854;regulation of antigen receptor-mediated signaling pathway;0.0369804164478388!GO:0016859;cis-trans isomerase activity;0.0369804164478388!GO:0002250;adaptive immune response;0.0372130247687003!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.0372130247687003!GO:0017166;vinculin binding;0.0373996729230599!GO:0007006;mitochondrial membrane organization and biogenesis;0.0379164998013877!GO:0000303;response to superoxide;0.0382566753732221!GO:0008276;protein methyltransferase activity;0.0388264601064729!GO:0006661;phosphatidylinositol biosynthetic process;0.0388546789922293!GO:0006470;protein amino acid dephosphorylation;0.0388879389506146!GO:0051101;regulation of DNA binding;0.0388879389506146!GO:0005869;dynactin complex;0.0392996993755754!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0393508613684987!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0393508613684987!GO:0006354;RNA elongation;0.0394106292125849!GO:0030133;transport vesicle;0.039647195991906!GO:0050671;positive regulation of lymphocyte proliferation;0.0396542694263372!GO:0032946;positive regulation of mononuclear cell proliferation;0.0396542694263372!GO:0050853;B cell receptor signaling pathway;0.0396542694263372!GO:0004721;phosphoprotein phosphatase activity;0.0396819623735633!GO:0035258;steroid hormone receptor binding;0.0399779766814616!GO:0000165;MAPKKK cascade;0.0399891249596569!GO:0042613;MHC class II protein complex;0.0400832098926337!GO:0043304;regulation of mast cell degranulation;0.0400832098926337!GO:0002448;mast cell mediated immunity;0.0409485426134598!GO:0043303;mast cell degranulation;0.0409485426134598!GO:0045767;regulation of anti-apoptosis;0.0410841648732156!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0416063872747422!GO:0032259;methylation;0.0420698614451333!GO:0045947;negative regulation of translational initiation;0.0421826510567813!GO:0019843;rRNA binding;0.0422865696538801!GO:0004518;nuclease activity;0.0426901553476028!GO:0051087;chaperone binding;0.0428365111857967!GO:0006516;glycoprotein catabolic process;0.0430161543934962!GO:0030137;COPI-coated vesicle;0.0430887323949652!GO:0000288;mRNA catabolic process, deadenylation-dependent decay;0.0431775398310927!GO:0048002;antigen processing and presentation of peptide antigen;0.0433293600200251!GO:0004402;histone acetyltransferase activity;0.0436911795006127!GO:0004468;lysine N-acetyltransferase activity;0.0436911795006127!GO:0009165;nucleotide biosynthetic process;0.0441858383477251!GO:0002718;regulation of cytokine production during immune response;0.044419344971746!GO:0002367;cytokine production during immune response;0.044419344971746!GO:0002700;regulation of production of molecular mediator of immune response;0.044419344971746!GO:0009112;nucleobase metabolic process;0.0448170857050623!GO:0032760;positive regulation of tumor necrosis factor production;0.0452623911989143!GO:0030663;COPI coated vesicle membrane;0.0452623911989143!GO:0030126;COPI vesicle coat;0.0452623911989143!GO:0002449;lymphocyte mediated immunity;0.0455611241268632!GO:0015980;energy derivation by oxidation of organic compounds;0.0474782267841191!GO:0032623;interleukin-2 production;0.0479353050072107!GO:0031461;cullin-RING ubiquitin ligase complex;0.0480702581891938!GO:0000049;tRNA binding;0.0487178005189389!GO:0015036;disulfide oxidoreductase activity;0.0490529521207535!GO:0000087;M phase of mitotic cell cycle;0.0490529521207535!GO:0032507;maintenance of cellular protein localization;0.0490578299657598!GO:0000781;chromosome, telomeric region;0.0493155916607679 | |||
|sample_id=11231 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=RUNX1..3:2.89148452218;ETS1,2:2.79949721398;PAX3,7:2.68338017176;FOXO1,3,4:2.44970482561;DMAP1_NCOR{1,2}_SMARC:2.4251704124;SPIB:2.36232536329;ELF1,2,4:2.32376066726;SPI1:2.31839869863;RORA:2.13302212782;FOX{D1,D2}:2.11075058218;ATF5_CREB3:2.080630817;PAX2:2.07562712027;CREB1:1.84110710093;FOXN1:1.81981076555;TGIF1:1.79898868722;NFIL3:1.66016283451;BPTF:1.65072520851;ATF4:1.61691392672;HMX1:1.61610127249;IRF1,2:1.56904589594;TLX2:1.56345994376;MAFB:1.52831330843;T:1.50140117616;NFKB1_REL_RELA:1.43787940179;EP300:1.402037568;FOX{F1,F2,J1}:1.36238857769;CDX1,2,4:1.32645306267;HIF1A:1.25729283587;CEBPA,B_DDIT3:1.20125572794;RFX2..5_RFXANK_RFXAP:1.17265267749;PITX1..3:1.15782606979;NANOG{mouse}:1.15518009476;IRF7:1.10399135124;HMGA1,2:1.0344710689;HOXA9_MEIS1:0.94614380415;JUN:0.931221802792;SREBF1,2:0.916189788138;FOXP1:0.911381275685;IKZF2:0.894415296146;RXRA_VDR{dimer}:0.863932225327;ATF2:0.861210925967;SMAD1..7,9:0.828647715354;NFATC1..3:0.808594972933;BREu{core}:0.769299317911;FOSL2:0.755521190347;HBP1_HMGB_SSRP1_UBTF:0.650052836582;FOXP3:0.578475053957;NKX2-1,4:0.556897421089;PAX6:0.540583288751;FOXA2:0.517981718176;ZBTB16:0.455406493043;GATA6:0.442764967928;BACH2:0.437197949769;HLF:0.432497927317;FOS_FOS{B,L1}_JUN{B,D}:0.416103598292;NFE2:0.387199869465;SOX2:0.37782130148;MYFfamily:0.286084353701;STAT2,4,6:0.265189365078;POU2F1..3:0.255790377641;ATF6:0.254619426988;EGR1..3:0.244910337439;POU5F1:0.234376737874;FOXD3:0.225572270598;MYB:0.215012330139;TBX4,5:0.186811731474;FOX{I1,J2}:0.150107989019;NFE2L2:0.136750817078;RREB1:0.133702653023;GLI1..3:0.105671715118;NANOG:0.101096348861;PDX1:0.0733251409235;TFAP4:0.0636045343681;ZEB1:0.00732428009426;NFE2L1:-0.00817392520212;TOPORS:-0.015507152142;STAT5{A,B}:-0.079286188163;LEF1_TCF7_TCF7L1,2:-0.0796570747662;MYOD1:-0.100325265111;AHR_ARNT_ARNT2:-0.108497708379;SPZ1:-0.140445104252;ESR1:-0.165802663625;MTE{core}:-0.205988189666;PAX4:-0.233070228651;NHLH1,2:-0.2355861267;SNAI1..3:-0.247447849251;MEF2{A,B,C,D}:-0.250873228609;MZF1:-0.26153726085;AIRE:-0.281177211244;ALX1:-0.305225741668;STAT1,3:-0.309086690409;ZFP161:-0.321714564112;NFIX:-0.330406733395;PAX5:-0.332244838415;GATA4:-0.346371669125;GCM1,2:-0.353903362872;NKX3-1:-0.360173654677;NKX2-2,8:-0.386756926392;HES1:-0.408956816402;NKX6-1,2:-0.418160339934;XBP1:-0.425702082059;SP1:-0.439339776902;CUX2:-0.452877016876;MED-1{core}:-0.455562677749;SRF:-0.463651719604;HNF4A_NR2F1,2:-0.469158017634;TAL1_TCF{3,4,12}:-0.471861581023;RBPJ:-0.477793733112;PATZ1:-0.482382101739;EVI1:-0.523007589048;ALX4:-0.523010002011;CRX:-0.523184513432;NR5A1,2:-0.527328199402;PRDM1:-0.528384989683;ELK1,4_GABP{A,B1}:-0.533243314592;ZNF148:-0.537627082435;DBP:-0.545900542048;OCT4_SOX2{dimer}:-0.565281010613;TFCP2:-0.578737326096;NR1H4:-0.586565318982;RFX1:-0.58778598405;PRRX1,2:-0.627834871571;ADNP_IRX_SIX_ZHX:-0.633628180694;MTF1:-0.642976896153;E2F1..5:-0.656923800506;FOXL1:-0.671665366756;SOX{8,9,10}:-0.678395267158;HNF1A:-0.681271211851;LMO2:-0.703432540019;SOX5:-0.715734504685;NRF1:-0.722331551315;PAX8:-0.72985668598;REST:-0.738394558786;TFDP1:-0.760570769346;NFY{A,B,C}:-0.760800938069;VSX1,2:-0.771428287954;TFAP2B:-0.785409288022;PBX1:-0.789190265909;ZNF238:-0.802702792647;AR:-0.863700946917;TFAP2{A,C}:-0.909618893424;ZNF384:-0.919069465799;ZNF423:-0.924719635119;MAZ:-0.944978995889;ESRRA:-0.951926052683;HOX{A6,A7,B6,B7}:-1.01066070193;HIC1:-1.02678925069;XCPE1{core}:-1.0268816972;FOXM1:-1.03087703837;POU1F1:-1.06777263588;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.07639939971;FOXQ1:-1.12269207697;NR3C1:-1.12867027343;ZBTB6:-1.13357493074;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-1.16022686625;HSF1,2:-1.16896445336;EN1,2:-1.17051022502;NR6A1:-1.20226547647;ZNF143:-1.23010594512;RXR{A,B,G}:-1.24050171012;NKX2-3_NKX2-5:-1.24503402775;YY1:-1.29056258044;KLF4:-1.32746142836;PPARG:-1.33191748222;CDC5L:-1.36383203755;bHLH_family:-1.39574895513;GTF2I:-1.40070633871;TBP:-1.42278910778;GFI1:-1.47112053064;GZF1:-1.50699948752;NKX3-2:-1.51151676493;TEF:-1.51499230149;TP53:-1.53005079661;ZIC1..3:-1.5338037283;TLX1..3_NFIC{dimer}:-1.53574367127;SOX17:-1.55300068416;GFI1B:-1.57406152105;HAND1,2:-1.61962445991;TEAD1:-1.63295342186;MYBL2:-1.68198576212;LHX3,4:-1.69131942309;POU6F1:-1.75082196742;GTF2A1,2:-1.75217243382;EBF1:-1.75908013574;HOX{A5,B5}:-1.76091655595;ARID5B:-1.84278779079;POU3F1..4:-1.88894039345;UFEwm:-1.95611358594;PAX1,9:-2.07479632185;ONECUT1,2:-2.1704735322;HOX{A4,D4}:-2.28230198536;IKZF1:-2.81397692667 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11231-116C7;search_select_hide=table117:FF:11231-116C7 | |||
}} | }} |
Latest revision as of 16:26, 3 June 2020
Name: | Peripheral Blood Mononuclear Cells, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs10860 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10860
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs10860
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.443 |
10 | 10 | 0.0148 |
100 | 100 | 0.443 |
101 | 101 | 0.428 |
102 | 102 | 0.711 |
103 | 103 | 0.6 |
104 | 104 | 0.592 |
105 | 105 | 0.167 |
106 | 106 | 0.00995 |
107 | 107 | 0.558 |
108 | 108 | 0.475 |
109 | 109 | 0.423 |
11 | 11 | 0.378 |
110 | 110 | 0.884 |
111 | 111 | 0.14 |
112 | 112 | 0.613 |
113 | 113 | 0.0422 |
114 | 114 | 0.205 |
115 | 115 | 0.152 |
116 | 116 | 0.321 |
117 | 117 | 0.0177 |
118 | 118 | 0.326 |
119 | 119 | 0.974 |
12 | 12 | 0.399 |
120 | 120 | 0.322 |
121 | 121 | 0.472 |
122 | 122 | 0.359 |
123 | 123 | 0.00346 |
124 | 124 | 0.364 |
125 | 125 | 0.796 |
126 | 126 | 0.206 |
127 | 127 | 0.413 |
128 | 128 | 0.234 |
129 | 129 | 0.752 |
13 | 13 | 0.693 |
130 | 130 | 0.244 |
131 | 131 | 0.683 |
132 | 132 | 0.108 |
133 | 133 | 0.474 |
134 | 134 | 0.879 |
135 | 135 | 0.31 |
136 | 136 | 0.635 |
137 | 137 | 5.08791e-4 |
138 | 138 | 0.113 |
139 | 139 | 0.0118 |
14 | 14 | 0.28 |
140 | 140 | 0.424 |
141 | 141 | 0.511 |
142 | 142 | 0.941 |
143 | 143 | 0.00588 |
144 | 144 | 0.75 |
145 | 145 | 0.986 |
146 | 146 | 0.816 |
147 | 147 | 0.0353 |
148 | 148 | 0.195 |
149 | 149 | 0.647 |
15 | 15 | 0.116 |
150 | 150 | 0.907 |
151 | 151 | 0.216 |
152 | 152 | 0.955 |
153 | 153 | 0.706 |
154 | 154 | 0.291 |
155 | 155 | 0.0682 |
156 | 156 | 0.561 |
157 | 157 | 0.899 |
158 | 158 | 0.00548 |
159 | 159 | 0.754 |
16 | 16 | 0.859 |
160 | 160 | 0.479 |
161 | 161 | 0.78 |
162 | 162 | 0.0556 |
163 | 163 | 0.776 |
164 | 164 | 0.252 |
165 | 165 | 0.229 |
166 | 166 | 0.613 |
167 | 167 | 0.453 |
168 | 168 | 0.154 |
169 | 169 | 0.952 |
17 | 17 | 0.765 |
18 | 18 | 0.566 |
19 | 19 | 0.399 |
2 | 2 | 0.846 |
20 | 20 | 0.748 |
21 | 21 | 0.75 |
22 | 22 | 0.948 |
23 | 23 | 0.211 |
24 | 24 | 0.432 |
25 | 25 | 0.0972 |
26 | 26 | 0.643 |
27 | 27 | 0.556 |
28 | 28 | 0.359 |
29 | 29 | 0.233 |
3 | 3 | 0.32 |
30 | 30 | 0.227 |
31 | 31 | 0.997 |
32 | 32 | 0.0196 |
33 | 33 | 0.454 |
34 | 34 | 0.886 |
35 | 35 | 0.153 |
36 | 36 | 0.208 |
37 | 37 | 0.359 |
38 | 38 | 0.675 |
39 | 39 | 0.662 |
4 | 4 | 0.804 |
40 | 40 | 0.871 |
41 | 41 | 0.034 |
42 | 42 | 0.278 |
43 | 43 | 0.117 |
44 | 44 | 0.593 |
45 | 45 | 0.739 |
46 | 46 | 0.451 |
47 | 47 | 0.679 |
48 | 48 | 0.646 |
49 | 49 | 0.107 |
5 | 5 | 0.211 |
50 | 50 | 0.656 |
51 | 51 | 0.541 |
52 | 52 | 0.757 |
53 | 53 | 0.103 |
54 | 54 | 0.627 |
55 | 55 | 0.824 |
56 | 56 | 0.849 |
57 | 57 | 0.94 |
58 | 58 | 0.0493 |
59 | 59 | 0.962 |
6 | 6 | 0.845 |
60 | 60 | 0.138 |
61 | 61 | 0.133 |
62 | 62 | 0.033 |
63 | 63 | 0.945 |
64 | 64 | 0.516 |
65 | 65 | 0.569 |
66 | 66 | 0.214 |
67 | 67 | 0.818 |
68 | 68 | 0.329 |
69 | 69 | 0.734 |
7 | 7 | 0.333 |
70 | 70 | 0.0782 |
71 | 71 | 0.0982 |
72 | 72 | 0.232 |
73 | 73 | 0.671 |
74 | 74 | 0.159 |
75 | 75 | 0.0836 |
76 | 76 | 0.119 |
77 | 77 | 0.169 |
78 | 78 | 0.341 |
79 | 79 | 0.857 |
8 | 8 | 0.662 |
80 | 80 | 0.0102 |
81 | 81 | 0.436 |
82 | 82 | 0.223 |
83 | 83 | 0.913 |
84 | 84 | 0.252 |
85 | 85 | 0.181 |
86 | 86 | 0.0469 |
87 | 87 | 0.812 |
88 | 88 | 0.604 |
89 | 89 | 0.215 |
9 | 9 | 0.447 |
90 | 90 | 0.0291 |
91 | 91 | 0.431 |
92 | 92 | 0.288 |
93 | 93 | 0.572 |
94 | 94 | 0.122 |
95 | 95 | 0.37 |
96 | 96 | 0.86 |
97 | 97 | 0.733 |
98 | 98 | 0.302 |
99 | 99 | 3.62659e-4 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs10860
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000135 human peripheral blood mononuclear cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0002371 (somatic cell)
0000219 (motile cell)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000226 (single nucleate cell)
0000080 (circulating cell)
0000842 (mononuclear cell)
UBERON: Anatomy
0000468 (multi-cellular organism)
0000178 (blood)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000179 (haemolymphatic fluid)
0000463 (organism substance)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0010317 (germ layer / neural crest derived structure)
0002390 (hematopoietic system)
0004535 (cardiovascular system)
0002193 (hemolymphoid system)
0001009 (circulatory system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000135 (human peripheral blood mononuclear cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)