FF:11554-120C6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005209 | ||
| | |accession_numbers=CAGE;DRX008292;DRR009164;DRZ000589;DRZ001974;DRZ011939;DRZ013324 | ||
| | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002097,UBERON:0002199,UBERON:0002384,UBERON:0000479,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0003102,UBERON:0002416 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002320,CL:0002371,CL:0000255,CL:0000057,CL:0002620 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000057,FF:0000250,FF:0000001,FF:0000252 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr9:132427883..132427951,+!p2@PRRX2!1.99!96.14!PRRX2;;chr9:132427972..132428056,+!p1@PRRX2!1.72!65.79!PRRX2;;chr1:197886461..197886558,+!p1@LHX9!1.70!49.17!LHX9;;chr7:19157248..19157268,-!p1@TWIST1!1.57!97.33!TWIST1;;chr12:54410664..54410684,+!p1@HOXC4,p1@HOXC5,p1@HOXC6!1.45!26.96!HOXC5;;chr6:10415276..10415341,-!p2@TFAP2A!1.43!31.37!TFAP2A;;chr11:46299199..46299233,+!p1@CREB3L1!1.38!115.81!CREB3L1;;chr1:170633348..170633399,+!p2@PRRX1!1.38!30.86!PRRX1;;chr1:170632285..170632309,+!p1@PRRX1!1.32!22.55!PRRX1;;chr6:134210243..134210257,+!p1@TCF21!1.30!18.99!TCF21;;chr4:81118647..81118666,+!p1@PRDM8!1.26!22.89!PRDM8;;chr6:1389789..1389821,+!p1@FOXF2!1.24!22.38!FOXF2;;chr2:239756739..239756755,+!p2@TWIST2!1.21!25.94!TWIST2;;chr6:10412600..10412637,-!p1@TFAP2A!1.20!24.93!TFAP2A;;chr15:57511609..57511651,+!p2@TCF12!1.20!24.76!TCF12;;chr2:239756671..239756732,+!p1@TWIST2!1.19!46.29!TWIST2;;chr7:27224842..27224872,-!p1@HOXA11!1.19!14.58!HOXA11;;chr7:27224795..27224840,-!p2@HOXA11!1.18!14.07!HOXA11;;chr10:28034739..28034756,-!p1@MKX!1.07!10.85!MKX;;chr3:128206762..128206781,-!p2@GATA2!1.06!65.62!GATA2;;chr11:65686802..65686818,+!p6@DRAP1!1.03!17.13!DRAP1;;chr5:72744594..72744609,-!p1@FOXD1!1.02!43.75!FOXD1;;chr2:176969228..176969260,+!p1@HOXD11!1.02!9.50!HOXD11;;chr12:54380404..54380433,+!p3@HOXC10!1.01!9.16!HOXC10;;chr5:321810..321877,+!p1@AHRR!0.99!28.83!AHRR;;chr11:65686732..65686756,+!p2@DRAP1!0.98!36.96!DRAP1;;chr11:46299539..46299620,+!p2@CREB3L1!0.97!14.24!CREB3L1;;chr5:72744445..72744466,-!p2@FOXD1!0.95!13.40!FOXD1;;chr3:128212033..128212051,-!p1@GATA2!0.94!7.63!GATA2;;chr5:139492456..139492489,+!p7@PURA!0.91!7.12!PURA;;chr7:27213893..27213954,-!p1@HOXA10!0.91!7.12!HOXA10;;chr1:23885981..23886002,-!p1@ID3!0.90!1272.04!ID3;;chr12:53614115..53614154,-!p1@RARG!0.89!38.32!RARG;;chr16:86544113..86544145,+!p1@FOXF1!0.89!8.48!FOXF1;;chr2:223163706..223163730,-!p1@PAX3!0.89!6.78!PAX3;;chr5:2751762..2751784,-!p1@IRX2!0.89!6.78!IRX2;;chr17:59477233..59477263,+!p1@TBX2!0.88!21.20!TBX2;;chr2:19558373..19558392,-!p1@OSR1!0.88!18.99!OSR1;;chr10:119303078..119303169,+!p2@EMX2!0.88!6.61!EMX2;;chr16:86600426..86600441,+!p1@FOXC2!0.87!16.62!FOXC2;;chr3:157823517..157823562,-!p1@SHOX2!0.86!6.78!SHOX2;;chr4:174450089..174450153,-!p2@HAND2!0.85!6.10!HAND2;;chrY:21906594..21906622,-!p1@KDM5D!0.84!5.93!KDM5D;;chr6:34204921..34204939,+!p3@HMGA1!0.83!186.01!HMGA1;;chr1:170632959..170632987,+!p4@PRRX1!0.83!6.44!PRRX1;;chr10:63809106..63809127,+!p1@ARID5B!0.82!82.07!ARID5B;;chr11:65687362..65687436,+!p3@DRAP1!0.82!27.64!DRAP1;;chr12:115121962..115121987,-!p1@TBX3!0.81!49.85!TBX3;;chr14:61116183..61116208,-!p1@SIX1!0.81!22.38!SIX1;;chr2:66662281..66662308,+!p1@MEIS1!0.81!20.01!MEIS1;;chr2:85981107..85981120,+!p3@ATOH8!0.81!5.43!ATOH8;;chr16:31076332..31076388,-!p3@ZNF668!0.81!5.43!ZNF668;;chr12:54378923..54378966,+!p1@HOXC10!0.81!5.43!HOXC10;;chr10:63809013..63809041,+!p3@ARID5B!0.80!31.54!ARID5B;;chr12:54380036..54380091,+!p4@HOXC10!0.80!5.26!HOXC10;;chr19:13134772..13134822,+!p2@NFIX!0.79!7.80!NFIX;;chr11:65687222..65687240,+!p7@DRAP1!0.79!6.78!DRAP1;;chr6:85473156..85473210,-!p2@TBX18!0.79!6.44!TBX18;;chr7:44143925..44143970,+!p1@AEBP1!0.78!121.91!AEBP1;;chr2:85980951..85981004,+!p1@ATOH8!0.78!8.48!ATOH8;;chr1:170633262..170633285,+!p3@PRRX1!0.78!5.77!PRRX1;;chr7:27239703..27239715,-!p1@HOXA13!0.78!5.09!HOXA13;;chr12:114845810..114845824,-!p1@TBX5!0.78!5.09!TBX5;;chr12:54379029..54379057,+!p2@HOXC10!0.78!5.09!HOXC10;;chr12:66218255..66218304,+!p3@HMGA2!0.77!14.24!HMGA2;;chr3:141121847..141121868,+!p5@ZBTB38!0.77!7.80!ZBTB38;;chr20:30193083..30193098,+!p1@ID1!0.76!423.22!ID1;;chr11:65686952..65686975,+!p5@DRAP1!0.75!27.98!DRAP1;;chr6:10412392..10412409,-!p4@TFAP2A!0.75!5.43!TFAP2A;;chr12:54393880..54393962,+!p1@HOXC9!0.75!4.58!HOXC9;;chr12:54410639..54410659,+!p2@HOXC4,p2@HOXC5,p2@HOXC6!0.75!4.58!HOXC5;;chr19:47523058..47523114,+!p1@NPAS1!0.75!4.58!NPAS1;;chr1:170632250..170632277,+!p7@PRRX1!0.75!4.58!PRRX1;;chr16:51185172..51185197,-!p1@SALL1!0.75!4.58!SALL1;;chr8:67525443..67525459,-!p2@MYBL1!0.74!6.95!MYBL1;;chr5:72743793..72743855,-!p4@FOXD1!0.74!5.43!FOXD1;;chr15:76629123..76629151,+!p1@ISL2!0.74!5.09!ISL2;;chr11:65687243..65687276,+!p8@DRAP1!0.73!6.10!DRAP1;;chr8:93074848..93074871,-!p3@RUNX1T1!0.73!4.41!RUNX1T1;;chr2:172967242..172967265,-!p2@DLX2!0.73!4.41!DLX2;;chr4:174451370..174451387,-!p1@HAND2!0.73!4.41!HAND2;;chr6:19837592..19837621,+!p1@ID4!0.72!29.16!ID4;;chr2:121493425..121493474,+!p1@GLI2!0.72!10.17!GLI2;;chr7:27205136..27205164,-!p1@HOXA9!0.72!4.24!HOXA9;;chr20:55204351..55204377,+!p1@TFAP2C!0.71!5.43!TFAP2C;;chr5:134369905..134369972,-!p1@PITX1!0.70!6.44!PITX1;;chr8:93074803..93074845,-!p1@RUNX1T1!0.70!4.07!RUNX1T1;;chrY:2803415..2803468,+!p1@ZFY!0.70!4.07!ZFY;;chr1:170633058..170633084,+!p5@PRRX1!0.70!4.07!PRRX1;;chr15:83953397..83953425,-!p1@BNC1!0.69!4.58!BNC1;;chr6:100912752..100912778,-!p2@SIM1!0.69!3.90!SIM1;;chr7:27205106..27205134,-!p2@HOXA9!0.69!3.90!HOXA9;;chr7:27239740..27239759,-!p2@HOXA13!0.69!3.90!HOXA13;;chr2:176969179..176969226,+!p2@HOXD11!0.69!3.90!HOXD11;;chr12:124873357..124873401,-!p1@NCOR2!0.68!50.70!NCOR2;;chr12:66218598..66218645,+!p2@HMGA2!0.67!19.33!HMGA2;;chr2:172967621..172967637,-!p1@DLX2!0.67!11.02!DLX2;;chr2:85981222..85981259,+!p2@ATOH8!0.67!6.44!ATOH8;;chr6:100912785..100912822,-!p1@SIM1!0.67!3.73!SIM1;;chr8:49833978..49833996,-!p1@SNAI2!0.66!85.63!SNAI2;;chr1:209979467..209979494,-!p1@IRF6!0.66!4.07!IRF6;;chr1:170632723..170632739,+!p8@PRRX1!0.66!3.56!PRRX1;;chr2:5832508..5832524,+!p1@SOX11!0.66!3.56!SOX11;;chr2:85981073..85981091,+!p5@ATOH8!0.66!3.56!ATOH8;;chr18:52969674..52969685,-!p24@TCF4!0.66!3.56!TCF4;;chr3:52001448..52001478,-!p2@PCBP4!0.65!56.80!PCBP4;;chr8:49833948..49833973,-!p2@SNAI2!0.65!25.26!SNAI2;;chr15:37392724..37392757,-!p1@MEIS2!0.65!18.48!MEIS2;;chr14:24837368..24837401,+!p1@NFATC4!0.64!8.82!NFATC4;;chr15:96869255..96869291,+!p6@NR2F2!0.64!6.61!NR2F2;;chr15:37392703..37392717,-!p8@MEIS2!0.64!5.09!MEIS2;;chr12:114843940..114843955,-!p2@TBX5!0.64!3.39!TBX5;;chr1:119530493..119530572,-!p1@TBX15!0.64!3.39!TBX15;;chr2:172949484..172949522,+!p1@DLX1!0.64!3.39!DLX1;;chr6:85474299..85474324,-!p1@TBX18!0.63!6.44!TBX18;;chr8:99956662..99956684,+!p1@OSR2!0.63!5.43!OSR2;;chr5:72744562..72744573,-!p3@FOXD1!0.63!4.24!FOXD1;;chr15:96869292..96869320,+!p15@NR2F2!0.61!4.75!NR2F2;;chr6:1389824..1389840,+!p3@FOXF2!0.61!3.05!FOXF2;;chr1:197886421..197886432,+!p2@LHX9!0.61!3.05!LHX9;;chr10:63809077..63809089,+!p5@ARID5B!0.60!7.29!ARID5B;;chr12:115122005..115122016,-!p3@TBX3!0.60!3.73!TBX3;;chr2:66662249..66662267,+!p2@MEIS1!0.59!13.23!MEIS1;;chr12:80085061..80085119,-!p6@PAWR!0.59!5.09!PAWR;;chr18:53068911..53068935,-!p4@TCF4!0.59!3.39!TCF4;;chr11:46299443..46299459,+!p4@CREB3L1!0.59!2.88!CREB3L1;;chr6:10412576..10412599,-!p5@TFAP2A!0.59!2.88!TFAP2A;;chr18:56532100..56532130,+!p1@ZNF532!0.58!5.77!ZNF532;;chr15:37390850..37390909,-!p3@MEIS2!0.57!6.10!MEIS2;;chr17:59477275..59477286,+!p3@TBX2!0.57!3.90!TBX2;;chr5:43067636..43067674,+!p6@ZNF131!0.57!3.90!ZNF131;;chr19:45260775..45260838,+!p5@BCL3!0.57!3.73!BCL3;;chr1:110613238..110613272,-!p1@ALX3!0.57!2.71!ALX3;;chr1:170632115..170632136,+!p9@PRRX1!0.57!2.71!PRRX1;;chr1:170632137..170632172,+!p10@PRRX1!0.57!2.71!PRRX1;;chr1:170632477..170632506,+!p6@PRRX1!0.57!2.71!PRRX1;;chr16:86612320..86612394,+!p1@FOXL1!0.57!2.71!FOXL1;;chr4:4861385..4861398,+!p1@MSX1!0.56!9.16!MSX1;;chr3:52001426..52001447,-!p3@PCBP4!0.55!8.65!PCBP4;;chr7:19157043..19157088,-!p2@TWIST1!0.55!7.46!TWIST1;;chr7:1577899..1577943,+!p3@MAFK!0.55!2.54!MAFK;;chr2:172950227..172950249,+!p2@DLX1!0.55!2.54!DLX1;;chr2:176969097..176969109,+!p3@HOXD11!0.55!2.54!HOXD11;;chr2:85981008..85981025,+!p7@ATOH8!0.55!2.54!ATOH8;;chr3:128207349..128207386,-!p3@GATA2!0.55!2.54!GATA2;;chr15:96869165..96869183,+!p20@NR2F2!0.55!2.54!NR2F2;;chr15:66994561..66994597,+!p2@SMAD6!0.54!6.95!SMAD6;;chr2:71127699..71127744,+!p1@VAX2!0.54!5.93!VAX2;;chr10:63809090..63809097,+!p7@ARID5B!0.54!3.73!ARID5B;;chr1:54204818..54204870,-!p@chr1:54204818..54204870,-!0.54!2.71!GLIS1;;chr2:85980919..85980942,+!p4@ATOH8!0.54!2.71!ATOH8;;chr11:65667884..65667895,-!p2@FOSL1!0.53!11.53!FOSL1;;chr11:46316699..46316719,+!p10@CREB3L1!0.53!2.37!CREB3L1;;chr12:54366975..54367001,+!p1@HOXC11!0.53!2.37!HOXC11;;chr12:54394309..54394336,+!p2@HOXC9!0.53!2.37!HOXC9;;chr2:176969124..176969155,+!p5@HOXD11!0.53!2.37!HOXD11;;chr2:85981027..85981047,+!p8@ATOH8!0.53!2.37!ATOH8;;chr6:1389989..1390019,+!p2@FOXF2!0.53!2.37!FOXF2;;chr19:12203100..12203132,+!p1@ZNF788!0.52!5.43!ZNF788;;chr12:66218183..66218209,+!p4@HMGA2!0.52!5.09!HMGA2;;chr7:44143978..44143989,+!p2@AEBP1!0.52!4.92!AEBP1;;chr12:66218212..66218244,+!p5@HMGA2!0.52!3.73!HMGA2;;chr20:42295745..42295765,+!p1@MYBL2!0.51!47.82!MYBL2;;chr15:96874012..96874042,+!p2@NR2F2!0.51!25.94!NR2F2;;chr11:65687158..65687216,+!p4@DRAP1!0.51!16.45!DRAP1;;chr16:54964740..54964789,+!p1@IRX5!0.51!3.56!IRX5;;chr11:12696071..12696086,+!p3@TEAD1!0.51!3.22!TEAD1;;chr9:16870659..16870675,-!p2@BNC2!0.51!2.88!BNC2;;chr15:37392534..37392562,-!p10@MEIS2!0.51!2.54!MEIS2;;chr15:80843484..80843499,+!p5@ARNT2!0.51!2.20!ARNT2;;chr2:66662396..66662407,+!p4@MEIS1!0.51!2.20!MEIS1;;chr9:16705069..16705086,-!p3@BNC2!0.51!2.20!BNC2;;chr12:115122318..115122331,-!p2@TBX3!0.51!2.20!TBX3;;chr5:176738887..176738934,-!p1@MXD3!0.50!18.82!MXD3;;chr18:72922743..72922761,+!p3@TSHZ1!0.50!8.82!TSHZ1;;chr15:66994663..66994680,+!p1@SMAD6!0.50!6.27!SMAD6;;chr12:66218836..66218888,+!p1@HMGA2!0.49!26.11!HMGA2;;chr12:2986206..2986258,-!p2@FOXM1!0.49!16.45!FOXM1;;chr4:1873011..1873063,+!p2@WHSC1!0.49!8.99!WHSC1;;chr20:42543506..42543549,+!p2@TOX2!0.49!6.10!TOX2;;chr6:1312325..1312340,+!p1@FOXQ1!0.49!3.90!FOXQ1;;chr20:62680984..62680999,-!p1@SOX18!0.49!3.05!SOX18;;chr7:44143997..44144008,+!p3@AEBP1!0.49!2.88!AEBP1;;chr6:31126291..31126399,+!p1@TCF19!0.48!25.43!TCF19;;chr12:124873852..124873881,-!p3@NCOR2!0.48!15.94!NCOR2;;chr10:63853436..63853442,+!p4@ARID5B!0.48!14.24!ARID5B;;chr2:121493492..121493537,+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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000057;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002620;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002097;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002416 | |||
|ffid_belonging_in_development=CL:0000134 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|top_motifs= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520walker%2520warburg%252c%2520donor1.CNhs11352.11554-120C6.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520walker%2520warburg%252c%2520donor1.CNhs11352.11554-120C6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520walker%2520warburg%252c%2520donor1.CNhs11352.11554-120C6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520walker%2520warburg%252c%2520donor1.CNhs11352.11554-120C6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Fibroblast%2520-%2520skin%2520walker%2520warburg%252c%2520donor1.CNhs11352.11554-120C6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11554-120C6 | |||
|is_a=EFO:0002091;;FF:0000252 | |||
|is_obsolete= | |||
|library_id=CNhs11352 | |||
|library_id_phase_based=2:CNhs11352 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11554 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11554 | |||
|name=Fibroblast - skin walker warburg, donor1 | |||
|namespace=FANTOM5 | |||
|part_of= | |||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11352,LSID769,release014,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,-0.209339405642681,-0.282403560576942,0,0,0,0.068022726550833,0,0,0,0,0,0,0,0,0,-0.153323010348428,0,0.0340113632754165,0,0,0,-0.0299351697172245,0,0,-0.132956589778862,0,0,0,0,0,0,0,0,0,0,0,0,-0.119783370137819,0,0.068022726550833,0,0.068022726550833,0,0,0,0,-0.0242150211128343,0,0,0,0.339833719722764,0,0.0188798984642461,0,-0.0289696346917721,0,0,0.081254017402096,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,-0.122096397163691,0,0,0,0,0,0,0.0704033276241136,0,0,0,-0.113922139233797,0.00413079829614701,0,0.178597644615193,0.0634099402725185,0,-0.0300126246868734,-0.138477200800895,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.104846976007705,0,0,0,-0.116618893451534,-0.227410940470482,0,0,0,0,0,0 | |||
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| |||
|rna_box=120 | |||
|rna_catalog_number=custom | |||
|rna_concentration=1.177 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-ethanol-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.1 | |||
|rna_od260/280=2.11 | |||
|rna_position=C6 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=120C6 | |||
|rna_weight_ug=158.94225 | |||
|sample_age=1 month old neonate | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=GM16192 | |||
|sample_cell_type=fibroblast | |||
|sample_collaboration=Splicing (contact: Al Forrest) | |||
|sample_company=Coriell | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=WALKER-WARBURG SYNDROME | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=C | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.19079711974056e-247!GO:0043226;organelle;8.55689686561623e-200!GO:0043229;intracellular organelle;1.50885663118221e-199!GO:0043231;intracellular membrane-bound organelle;1.72544435953666e-194!GO:0043227;membrane-bound organelle;4.3154164797508e-194!GO:0005737;cytoplasm;1.89127059586915e-188!GO:0044422;organelle part;3.03006205922719e-150!GO:0044446;intracellular organelle part;6.50247113633451e-149!GO:0044444;cytoplasmic part;1.93330748801808e-132!GO:0032991;macromolecular complex;1.59574685800906e-103!GO:0030529;ribonucleoprotein complex;3.13607717897891e-89!GO:0044238;primary metabolic process;1.74348631216685e-87!GO:0044237;cellular metabolic process;5.52219945436862e-87!GO:0043170;macromolecule metabolic process;1.8595381893054e-84!GO:0005515;protein binding;2.53279054107066e-84!GO:0005634;nucleus;5.87423256250505e-80!GO:0043233;organelle lumen;1.21018079109314e-74!GO:0031974;membrane-enclosed lumen;1.21018079109314e-74!GO:0044428;nuclear part;1.06103443958568e-73!GO:0003723;RNA binding;1.08637031417579e-68!GO:0005739;mitochondrion;2.74072691292967e-66!GO:0016043;cellular component organization and biogenesis;2.99797215796791e-55!GO:0005840;ribosome;6.14263569283948e-54!GO:0043234;protein complex;5.22050343369975e-52!GO:0006412;translation;1.52238580353316e-50!GO:0019538;protein metabolic process;1.12349677757541e-49!GO:0006396;RNA processing;7.69972722169896e-48!GO:0003735;structural constituent of ribosome;8.58330456589125e-48!GO:0031090;organelle membrane;3.06396909373234e-47!GO:0043283;biopolymer metabolic process;4.46111218528803e-46!GO:0031981;nuclear lumen;1.59713847875248e-44!GO:0044429;mitochondrial part;2.08902364418108e-44!GO:0044260;cellular macromolecule metabolic process;7.01034155512992e-44!GO:0015031;protein transport;1.39417553562796e-43!GO:0033036;macromolecule localization;2.42482453499761e-43!GO:0044267;cellular protein metabolic process;3.73970519723021e-43!GO:0010467;gene expression;6.42544896043983e-42!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.89234225249778e-40!GO:0033279;ribosomal subunit;1.92108869429034e-40!GO:0008104;protein localization;4.2007554373249e-40!GO:0045184;establishment of protein localization;7.81883356332675e-40!GO:0005829;cytosol;8.96655071610118e-40!GO:0043228;non-membrane-bound organelle;1.92973575724948e-39!GO:0043232;intracellular non-membrane-bound organelle;1.92973575724948e-39!GO:0031967;organelle envelope;1.24856428034818e-38!GO:0044249;cellular biosynthetic process;2.32675988418385e-38!GO:0009058;biosynthetic process;2.56853054973635e-38!GO:0031975;envelope;3.03331204523366e-38!GO:0009059;macromolecule biosynthetic process;3.53440051295223e-38!GO:0006996;organelle organization and biogenesis;4.14289378697676e-38!GO:0016071;mRNA metabolic process;6.28950887702006e-38!GO:0046907;intracellular transport;6.21658156863451e-37!GO:0008380;RNA splicing;1.64963658020542e-35!GO:0006397;mRNA processing;1.56295717816485e-33!GO:0065003;macromolecular complex assembly;1.53402926266944e-32!GO:0022613;ribonucleoprotein complex biogenesis and assembly;3.44838192521023e-31!GO:0022607;cellular component assembly;3.17296867939852e-30!GO:0006886;intracellular protein transport;4.40337026817542e-30!GO:0005830;cytosolic ribosome (sensu Eukaryota);7.04364666626678e-29!GO:0006259;DNA metabolic process;1.6511951283658e-28!GO:0005740;mitochondrial envelope;5.67664589141011e-28!GO:0005654;nucleoplasm;1.2761361394353e-27!GO:0031966;mitochondrial membrane;2.96949589901532e-26!GO:0005681;spliceosome;6.16319800110248e-26!GO:0019866;organelle inner membrane;7.3585335782549e-26!GO:0007049;cell cycle;2.47595320670669e-25!GO:0005743;mitochondrial inner membrane;3.88662630389277e-24!GO:0051649;establishment of cellular localization;7.40752695286958e-24!GO:0000166;nucleotide binding;1.44742934073844e-23!GO:0051641;cellular localization;1.6311192841696e-23!GO:0044445;cytosolic part;5.47818936989265e-23!GO:0003676;nucleic acid binding;6.21663266230685e-23!GO:0044451;nucleoplasm part;1.99696638641281e-22!GO:0006119;oxidative phosphorylation;4.18766599661267e-22!GO:0016462;pyrophosphatase activity;1.57568266075699e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.95994133073687e-21!GO:0016817;hydrolase activity, acting on acid anhydrides;3.17336849944219e-21!GO:0015935;small ribosomal subunit;5.75645501971028e-21!GO:0017111;nucleoside-triphosphatase activity;7.41283454669729e-21!GO:0006457;protein folding;7.41283454669729e-21!GO:0015934;large ribosomal subunit;1.63493936653229e-20!GO:0000278;mitotic cell cycle;4.52866113516822e-20!GO:0044455;mitochondrial membrane part;7.24466218557332e-20!GO:0031980;mitochondrial lumen;1.49624774547184e-19!GO:0005759;mitochondrial matrix;1.49624774547184e-19!GO:0022402;cell cycle process;1.66689723182523e-19!GO:0005783;endoplasmic reticulum;3.37289330656431e-19!GO:0048770;pigment granule;5.85789585542573e-19!GO:0042470;melanosome;5.85789585542573e-19!GO:0012505;endomembrane system;6.5587755319829e-19!GO:0016070;RNA metabolic process;1.02816118843208e-17!GO:0022618;protein-RNA complex assembly;1.04210174890023e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.74694146120866e-17!GO:0005730;nucleolus;1.8788470004419e-17!GO:0016874;ligase activity;4.14147690555925e-17!GO:0032553;ribonucleotide binding;4.20067631418193e-17!GO:0032555;purine ribonucleotide binding;4.20067631418193e-17!GO:0017076;purine nucleotide binding;9.0133963067644e-17!GO:0005746;mitochondrial respiratory chain;1.74374476396895e-16!GO:0008134;transcription factor binding;1.74374476396895e-16!GO:0006974;response to DNA damage stimulus;5.21813146034499e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;6.31127799606925e-16!GO:0005761;mitochondrial ribosome;8.59739470367854e-16!GO:0000313;organellar ribosome;8.59739470367854e-16!GO:0044432;endoplasmic reticulum part;1.12472861278427e-15!GO:0006512;ubiquitin cycle;1.22394492577544e-15!GO:0048193;Golgi vesicle transport;1.6897061861946e-15!GO:0044265;cellular macromolecule catabolic process;1.87839079819268e-15!GO:0008135;translation factor activity, nucleic acid binding;1.9614768826481e-15!GO:0005694;chromosome;2.05545064640577e-15!GO:0000087;M phase of mitotic cell cycle;2.47923339887549e-15!GO:0007067;mitosis;3.01884909582644e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);3.01884909582644e-15!GO:0051186;cofactor metabolic process;3.56015110550591e-15!GO:0022403;cell cycle phase;3.5857238000894e-15!GO:0043285;biopolymer catabolic process;5.71146346444233e-15!GO:0006605;protein targeting;5.74523150997585e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;6.34771823856471e-15!GO:0050136;NADH dehydrogenase (quinone) activity;6.85961698444418e-15!GO:0003954;NADH dehydrogenase activity;6.85961698444418e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;6.85961698444418e-15!GO:0019941;modification-dependent protein catabolic process;1.15333797625913e-14!GO:0043632;modification-dependent macromolecule catabolic process;1.15333797625913e-14!GO:0051082;unfolded protein binding;1.6496395107823e-14!GO:0044257;cellular protein catabolic process;1.90636165134706e-14!GO:0006511;ubiquitin-dependent protein catabolic process;1.93947437771675e-14!GO:0005794;Golgi apparatus;2.78406029153855e-14!GO:0005524;ATP binding;3.28259196942402e-14!GO:0009057;macromolecule catabolic process;3.56582950728031e-14!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);3.69264935139262e-14!GO:0000398;nuclear mRNA splicing, via spliceosome;4.27928872460601e-14!GO:0000375;RNA splicing, via transesterification reactions;4.27928872460601e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.27928872460601e-14!GO:0044427;chromosomal part;4.4343447242369e-14!GO:0042254;ribosome biogenesis and assembly;4.46056706292874e-14!GO:0032559;adenyl ribonucleotide binding;5.88071896502347e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.22657240454125e-13!GO:0030554;adenyl nucleotide binding;1.82111333283865e-13!GO:0051301;cell division;2.19469533633434e-13!GO:0030163;protein catabolic process;2.51674151462076e-13!GO:0042775;organelle ATP synthesis coupled electron transport;2.81482690015528e-13!GO:0042773;ATP synthesis coupled electron transport;2.81482690015528e-13!GO:0030964;NADH dehydrogenase complex (quinone);3.58919833913663e-13!GO:0045271;respiratory chain complex I;3.58919833913663e-13!GO:0005747;mitochondrial respiratory chain complex I;3.58919833913663e-13!GO:0006281;DNA repair;4.34033637408687e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;9.19230824994272e-13!GO:0051276;chromosome organization and biogenesis;1.71541092267868e-12!GO:0044248;cellular catabolic process;2.32520734695241e-12!GO:0016192;vesicle-mediated transport;3.71540464358789e-12!GO:0009719;response to endogenous stimulus;3.86785756534894e-12!GO:0000279;M phase;4.49260772237304e-12!GO:0009055;electron carrier activity;7.6545843816074e-12!GO:0003743;translation initiation factor activity;9.00254204930384e-12!GO:0043412;biopolymer modification;1.10900050654252e-11!GO:0006732;coenzyme metabolic process;1.12577484159397e-11!GO:0005635;nuclear envelope;1.95972399186359e-11!GO:0006413;translational initiation;2.16066940792545e-11!GO:0005793;ER-Golgi intermediate compartment;4.1350038872041e-11!GO:0003712;transcription cofactor activity;4.54141630751149e-11!GO:0042623;ATPase activity, coupled;5.19347694916781e-11!GO:0042175;nuclear envelope-endoplasmic reticulum network;5.50208130434552e-11!GO:0044453;nuclear membrane part;6.18846218341315e-11!GO:0006260;DNA replication;6.27419890246279e-11!GO:0009259;ribonucleotide metabolic process;7.98903782935139e-11!GO:0031965;nuclear membrane;8.75979598347352e-11!GO:0016887;ATPase activity;1.02661631411762e-10!GO:0006913;nucleocytoplasmic transport;1.45928974762428e-10!GO:0006325;establishment and/or maintenance of chromatin architecture;1.48995083595489e-10!GO:0005789;endoplasmic reticulum membrane;1.77509261168903e-10!GO:0006464;protein modification process;2.12417247897051e-10!GO:0051169;nuclear transport;3.32112652227099e-10!GO:0016604;nuclear body;3.86004347882509e-10!GO:0006399;tRNA metabolic process;4.16331797160332e-10!GO:0006163;purine nucleotide metabolic process;4.47169342217465e-10!GO:0006323;DNA packaging;5.10753100044108e-10!GO:0000074;regulation of progression through cell cycle;6.1331649641939e-10!GO:0048523;negative regulation of cellular process;6.58022366685705e-10!GO:0051726;regulation of cell cycle;6.64662581409811e-10!GO:0012501;programmed cell death;7.16236756620174e-10!GO:0009260;ribonucleotide biosynthetic process;8.12366232737837e-10!GO:0006446;regulation of translational initiation;8.19391951240404e-10!GO:0009150;purine ribonucleotide metabolic process;8.98256188244749e-10!GO:0008565;protein transporter activity;9.8106391152839e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.24576514227349e-09!GO:0006915;apoptosis;1.36272201228816e-09!GO:0006164;purine nucleotide biosynthetic process;1.63715837990464e-09!GO:0008639;small protein conjugating enzyme activity;2.46244091882902e-09!GO:0065004;protein-DNA complex assembly;2.60435288648444e-09!GO:0006366;transcription from RNA polymerase II promoter;2.60665719495847e-09!GO:0043687;post-translational protein modification;2.60665719495847e-09!GO:0006364;rRNA processing;2.85297887253161e-09!GO:0006461;protein complex assembly;2.92154946086533e-09!GO:0009152;purine ribonucleotide biosynthetic process;3.14884220420995e-09!GO:0019787;small conjugating protein ligase activity;3.79632256088816e-09!GO:0004386;helicase activity;3.85929820633845e-09!GO:0004842;ubiquitin-protein ligase activity;4.32325572487271e-09!GO:0006888;ER to Golgi vesicle-mediated transport;4.32325572487271e-09!GO:0065002;intracellular protein transport across a membrane;4.66705786779281e-09!GO:0015630;microtubule cytoskeleton;4.96912946943941e-09!GO:0050794;regulation of cellular process;5.01343391503124e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.08947377186959e-09!GO:0008026;ATP-dependent helicase activity;5.9213898764488e-09!GO:0005643;nuclear pore;6.25772514429096e-09!GO:0008219;cell death;6.5382347451793e-09!GO:0016265;death;6.5382347451793e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;6.6611441932771e-09!GO:0016072;rRNA metabolic process;7.24810777501679e-09!GO:0009199;ribonucleoside triphosphate metabolic process;8.62113070217677e-09!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.04432502205553e-08!GO:0004812;aminoacyl-tRNA ligase activity;1.04432502205553e-08!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.04432502205553e-08!GO:0000785;chromatin;1.10385366576269e-08!GO:0009060;aerobic respiration;1.11356485705937e-08!GO:0009141;nucleoside triphosphate metabolic process;1.15018439357101e-08!GO:0045333;cellular respiration;1.768740374494e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.7906057294547e-08!GO:0009144;purine nucleoside triphosphate metabolic process;1.7906057294547e-08!GO:0043038;amino acid activation;1.83842215182751e-08!GO:0006418;tRNA aminoacylation for protein translation;1.83842215182751e-08!GO:0043039;tRNA aminoacylation;1.83842215182751e-08!GO:0003924;GTPase activity;1.83842215182751e-08!GO:0006333;chromatin assembly or disassembly;2.18549370721882e-08!GO:0048519;negative regulation of biological process;2.52957377838613e-08!GO:0030120;vesicle coat;2.62114635603988e-08!GO:0030662;coated vesicle membrane;2.62114635603988e-08!GO:0030532;small nuclear ribonucleoprotein complex;2.76350106926279e-08!GO:0015986;ATP synthesis coupled proton transport;3.46014629083717e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.46014629083717e-08!GO:0016607;nuclear speck;3.53867404861405e-08!GO:0017038;protein import;4.8386238910307e-08!GO:0009142;nucleoside triphosphate biosynthetic process;5.33507850589561e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;5.33507850589561e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;7.19431536760807e-08!GO:0005788;endoplasmic reticulum lumen;7.7636252671335e-08!GO:0016881;acid-amino acid ligase activity;8.2396119149647e-08!GO:0046930;pore complex;9.55513534533989e-08!GO:0046034;ATP metabolic process;9.82292773330291e-08!GO:0048475;coated membrane;9.82292773330291e-08!GO:0030117;membrane coat;9.82292773330291e-08!GO:0019829;cation-transporting ATPase activity;1.0972350436403e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.14597355486606e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.14597355486606e-07!GO:0050657;nucleic acid transport;1.25866019620157e-07!GO:0051236;establishment of RNA localization;1.25866019620157e-07!GO:0050658;RNA transport;1.25866019620157e-07!GO:0005667;transcription factor complex;1.52685775022607e-07!GO:0006403;RNA localization;1.67886324491975e-07!GO:0051188;cofactor biosynthetic process;1.7275411476605e-07!GO:0006099;tricarboxylic acid cycle;2.12817619878795e-07!GO:0046356;acetyl-CoA catabolic process;2.12817619878795e-07!GO:0005839;proteasome core complex (sensu Eukaryota);2.82869170639106e-07!GO:0051246;regulation of protein metabolic process;2.94333394081838e-07!GO:0051187;cofactor catabolic process;3.16000281708935e-07!GO:0007005;mitochondrion organization and biogenesis;3.22952089314124e-07!GO:0009056;catabolic process;3.23552239028873e-07!GO:0003697;single-stranded DNA binding;3.27546908443327e-07!GO:0006334;nucleosome assembly;3.69333110697842e-07!GO:0007010;cytoskeleton organization and biogenesis;4.4745638334934e-07!GO:0043069;negative regulation of programmed cell death;4.61518909636526e-07!GO:0015078;hydrogen ion transmembrane transporter activity;4.73159038805744e-07!GO:0006916;anti-apoptosis;5.33393864168275e-07!GO:0006754;ATP biosynthetic process;5.36051006836733e-07!GO:0006753;nucleoside phosphate metabolic process;5.36051006836733e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;6.09967102073889e-07!GO:0005819;spindle;6.26667114715673e-07!GO:0009109;coenzyme catabolic process;6.35171676575778e-07!GO:0016469;proton-transporting two-sector ATPase complex;6.49756413226249e-07!GO:0016491;oxidoreductase activity;8.44732900523296e-07!GO:0006084;acetyl-CoA metabolic process;8.44732900523296e-07!GO:0005768;endosome;9.47645948511561e-07!GO:0043066;negative regulation of apoptosis;9.60056797314514e-07!GO:0031497;chromatin assembly;1.04745668230107e-06!GO:0043067;regulation of programmed cell death;1.09904755816508e-06!GO:0043566;structure-specific DNA binding;1.1644138580709e-06!GO:0009117;nucleotide metabolic process;1.23791526952317e-06!GO:0042981;regulation of apoptosis;1.24881309095302e-06!GO:0050789;regulation of biological process;1.41069157627415e-06!GO:0031324;negative regulation of cellular metabolic process;1.90266216156334e-06!GO:0004298;threonine endopeptidase activity;2.07183628372817e-06!GO:0045259;proton-transporting ATP synthase complex;2.21127895162345e-06!GO:0016023;cytoplasmic membrane-bound vesicle;2.66520337398068e-06!GO:0051789;response to protein stimulus;2.72140096409179e-06!GO:0006986;response to unfolded protein;2.72140096409179e-06!GO:0044431;Golgi apparatus part;3.17230423313827e-06!GO:0031988;membrane-bound vesicle;3.63510182193901e-06!GO:0000245;spliceosome assembly;3.73536834480426e-06!GO:0005798;Golgi-associated vesicle;3.93168897974631e-06!GO:0032446;protein modification by small protein conjugation;4.71694732734191e-06!GO:0016853;isomerase activity;5.03202524054419e-06!GO:0051028;mRNA transport;5.03202524054419e-06!GO:0000151;ubiquitin ligase complex;5.80331690000181e-06!GO:0016567;protein ubiquitination;6.3560296245814e-06!GO:0016049;cell growth;6.44204076328965e-06!GO:0006613;cotranslational protein targeting to membrane;6.83711573269199e-06!GO:0016779;nucleotidyltransferase activity;6.84150918497058e-06!GO:0009108;coenzyme biosynthetic process;6.8500758480409e-06!GO:0003724;RNA helicase activity;7.05386603395856e-06!GO:0008361;regulation of cell size;7.07330313595029e-06!GO:0043623;cellular protein complex assembly;7.26243765399076e-06!GO:0006752;group transfer coenzyme metabolic process;7.35533060999763e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.37438097252359e-06!GO:0030036;actin cytoskeleton organization and biogenesis;7.52298933096058e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.24207778789756e-06!GO:0005525;GTP binding;8.35639985634643e-06!GO:0051329;interphase of mitotic cell cycle;9.33858039960334e-06!GO:0006793;phosphorus metabolic process;9.34903750738243e-06!GO:0006796;phosphate metabolic process;9.34903750738243e-06!GO:0051170;nuclear import;1.01547128150617e-05!GO:0005762;mitochondrial large ribosomal subunit;1.03763643620825e-05!GO:0000315;organellar large ribosomal subunit;1.03763643620825e-05!GO:0019843;rRNA binding;1.08405824591478e-05!GO:0016568;chromatin modification;1.10137439651377e-05!GO:0051325;interphase;1.10804697018844e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.19531604765308e-05!GO:0007051;spindle organization and biogenesis;1.30782526414062e-05!GO:0000775;chromosome, pericentric region;1.39110654497536e-05!GO:0003713;transcription coactivator activity;1.43716023143463e-05!GO:0005813;centrosome;1.57661521266396e-05!GO:0003714;transcription corepressor activity;1.57661521266396e-05!GO:0016564;transcription repressor activity;1.58029954644331e-05!GO:0031252;leading edge;1.70885652833406e-05!GO:0009892;negative regulation of metabolic process;1.72626649137786e-05!GO:0015980;energy derivation by oxidation of organic compounds;1.81041726381882e-05!GO:0016740;transferase activity;1.82070861275199e-05!GO:0016310;phosphorylation;1.8773649137131e-05!GO:0044440;endosomal part;1.90983218830389e-05!GO:0010008;endosome membrane;1.90983218830389e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.02237000691179e-05!GO:0045454;cell redox homeostasis;2.11181492479908e-05!GO:0030867;rough endoplasmic reticulum membrane;2.2315309373885e-05!GO:0006606;protein import into nucleus;2.30961914638243e-05!GO:0016787;hydrolase activity;2.54981404780538e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.6918508190619e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;2.7173097259234e-05!GO:0005815;microtubule organizing center;3.11061188663849e-05!GO:0016563;transcription activator activity;3.20374731735159e-05!GO:0006091;generation of precursor metabolites and energy;3.69092523493267e-05!GO:0016859;cis-trans isomerase activity;3.71180519187547e-05!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;4.63198453898217e-05!GO:0001558;regulation of cell growth;4.72122016139914e-05!GO:0043021;ribonucleoprotein binding;5.37342337596746e-05!GO:0032561;guanyl ribonucleotide binding;5.44036027908287e-05!GO:0019001;guanyl nucleotide binding;5.44036027908287e-05!GO:0000314;organellar small ribosomal subunit;5.46858905952991e-05!GO:0005763;mitochondrial small ribosomal subunit;5.46858905952991e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;6.01490867870127e-05!GO:0051427;hormone receptor binding;6.65778158347631e-05!GO:0045786;negative regulation of progression through cell cycle;6.72108269581135e-05!GO:0003899;DNA-directed RNA polymerase activity;6.72283107444261e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;6.7375685269306e-05!GO:0008654;phospholipid biosynthetic process;6.89694227210044e-05!GO:0030029;actin filament-based process;7.5701110087992e-05!GO:0031410;cytoplasmic vesicle;7.81644862892588e-05!GO:0030133;transport vesicle;7.87767297181636e-05!GO:0031982;vesicle;8.01868871507839e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;9.57298507331742e-05!GO:0019222;regulation of metabolic process;0.00011331312322486!GO:0008092;cytoskeletal protein binding;0.000117738561022621!GO:0006261;DNA-dependent DNA replication;0.000125425663800252!GO:0000139;Golgi membrane;0.000126169277804425!GO:0006612;protein targeting to membrane;0.000143745250775037!GO:0035257;nuclear hormone receptor binding;0.000144005682355898!GO:0005770;late endosome;0.000156079488080153!GO:0016481;negative regulation of transcription;0.000167250279272212!GO:0005905;coated pit;0.000172024798692752!GO:0031968;organelle outer membrane;0.000187052613616771!GO:0033116;ER-Golgi intermediate compartment membrane;0.000191077612810459!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000193938098767749!GO:0051168;nuclear export;0.000197533878095408!GO:0006414;translational elongation;0.00019797847715718!GO:0000075;cell cycle checkpoint;0.000199587360950537!GO:0008186;RNA-dependent ATPase activity;0.000200239441186476!GO:0005048;signal sequence binding;0.000200239441186476!GO:0008094;DNA-dependent ATPase activity;0.000206938525149824!GO:0019867;outer membrane;0.000208471930520792!GO:0030663;COPI coated vesicle membrane;0.000228458607799337!GO:0030126;COPI vesicle coat;0.000228458607799337!GO:0005874;microtubule;0.000254019034588895!GO:0005657;replication fork;0.000258086888112025!GO:0005885;Arp2/3 protein complex;0.000266960520079159!GO:0005773;vacuole;0.00032284878522084!GO:0008250;oligosaccharyl transferase complex;0.000335255164310621!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000340193949312455!GO:0043284;biopolymer biosynthetic process;0.000353703555508959!GO:0006626;protein targeting to mitochondrion;0.000374073128863169!GO:0019899;enzyme binding;0.000375289822106685!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000500735972837641!GO:0005769;early endosome;0.000519808438765972!GO:0048522;positive regulation of cellular process;0.000520369722501725!GO:0030137;COPI-coated vesicle;0.000537878037460303!GO:0004576;oligosaccharyl transferase activity;0.000543380979285878!GO:0005741;mitochondrial outer membrane;0.000569862153023215!GO:0004004;ATP-dependent RNA helicase activity;0.000573068769807894!GO:0003684;damaged DNA binding;0.000608561406373965!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000661717008405604!GO:0000786;nucleosome;0.000698319699586132!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000699393507474184!GO:0016363;nuclear matrix;0.000703904558868177!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.000706019200218339!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00071049369599387!GO:0043681;protein import into mitochondrion;0.000737432878046506!GO:0051252;regulation of RNA metabolic process;0.000798801661508336!GO:0006839;mitochondrial transport;0.000816353555921649!GO:0051920;peroxiredoxin activity;0.000818819861569333!GO:0006891;intra-Golgi vesicle-mediated transport;0.000864993614698976!GO:0046474;glycerophospholipid biosynthetic process;0.000897251013276586!GO:0009165;nucleotide biosynthetic process;0.000960058325432471!GO:0030880;RNA polymerase complex;0.00101452791897362!GO:0048471;perinuclear region of cytoplasm;0.00109478789668021!GO:0044452;nucleolar part;0.00118024370150961!GO:0003682;chromatin binding;0.001212126721777!GO:0065007;biological regulation;0.0012209652392192!GO:0007088;regulation of mitosis;0.00134349746523327!GO:0007243;protein kinase cascade;0.00137332132321306!GO:0018196;peptidyl-asparagine modification;0.00137332132321306!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00137332132321306!GO:0044262;cellular carbohydrate metabolic process;0.00140061312791778!GO:0000323;lytic vacuole;0.00144260531765262!GO:0005764;lysosome;0.00144260531765262!GO:0031072;heat shock protein binding;0.0014607500066622!GO:0006383;transcription from RNA polymerase III promoter;0.00148486892116712!GO:0000082;G1/S transition of mitotic cell cycle;0.00151781128085433!GO:0005791;rough endoplasmic reticulum;0.00152921895578658!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00152921895578658!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00152921895578658!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00152921895578658!GO:0005684;U2-dependent spliceosome;0.00160094639832662!GO:0000776;kinetochore;0.00164721512495328!GO:0003729;mRNA binding;0.0016547865493385!GO:0048500;signal recognition particle;0.00168451963014451!GO:0005852;eukaryotic translation initiation factor 3 complex;0.0018943099385526!GO:0000059;protein import into nucleus, docking;0.00203572805045138!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00204967633266735!GO:0042802;identical protein binding;0.00205844317766065!GO:0046489;phosphoinositide biosynthetic process;0.00215716769635969!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0023502772528998!GO:0000428;DNA-directed RNA polymerase complex;0.0023502772528998!GO:0030658;transport vesicle membrane;0.00240968259304126!GO:0008033;tRNA processing;0.00251909365128184!GO:0015631;tubulin binding;0.00268158495827532!GO:0007006;mitochondrial membrane organization and biogenesis;0.00270686632626477!GO:0030176;integral to endoplasmic reticulum membrane;0.00278068927605494!GO:0048487;beta-tubulin binding;0.00280233145944149!GO:0040008;regulation of growth;0.00286473469988238!GO:0043488;regulation of mRNA stability;0.00287192653362379!GO:0043487;regulation of RNA stability;0.00287192653362379!GO:0030134;ER to Golgi transport vesicle;0.00287585463827111!GO:0030521;androgen receptor signaling pathway;0.00289959992104828!GO:0003711;transcription elongation regulator activity;0.00292559553278971!GO:0003678;DNA helicase activity;0.00293378721987474!GO:0030132;clathrin coat of coated pit;0.00309074007865207!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.00314738734026651!GO:0051087;chaperone binding;0.003211029127505!GO:0046483;heterocycle metabolic process;0.00343842106571031!GO:0003690;double-stranded DNA binding;0.00344963050812061!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.00348979611868703!GO:0015399;primary active transmembrane transporter activity;0.00348979611868703!GO:0006302;double-strand break repair;0.0035206265675338!GO:0015992;proton transport;0.00354571376453198!GO:0008312;7S RNA binding;0.00368331493041037!GO:0007052;mitotic spindle organization and biogenesis;0.00370249308240068!GO:0001726;ruffle;0.0037569148798272!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00379598753954662!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00379598753954662!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.00410264214293577!GO:0003746;translation elongation factor activity;0.00432539612302723!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00434354153239909!GO:0045047;protein targeting to ER;0.00434354153239909!GO:0006818;hydrogen transport;0.00435181590658373!GO:0006402;mRNA catabolic process;0.00437722503565922!GO:0008180;signalosome;0.00439524791733542!GO:0035258;steroid hormone receptor binding;0.00443258430701044!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00447399259504924!GO:0006979;response to oxidative stress;0.00448091813376129!GO:0031124;mRNA 3'-end processing;0.00466821830579668!GO:0007093;mitotic cell cycle checkpoint;0.00468121619316709!GO:0030127;COPII vesicle coat;0.00468121619316709!GO:0012507;ER to Golgi transport vesicle membrane;0.00468121619316709!GO:0017166;vinculin binding;0.00482688677403749!GO:0032508;DNA duplex unwinding;0.00491798532755985!GO:0032392;DNA geometric change;0.00491798532755985!GO:0045045;secretory pathway;0.00502014180971716!GO:0030118;clathrin coat;0.00503291799904681!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00515307144639757!GO:0008139;nuclear localization sequence binding;0.00517760830395117!GO:0009112;nucleobase metabolic process;0.00524348490714807!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00524348490714807!GO:0030659;cytoplasmic vesicle membrane;0.00563316517940192!GO:0007050;cell cycle arrest;0.00579271809104035!GO:0000910;cytokinesis;0.00581664474176281!GO:0006595;polyamine metabolic process;0.00606356401287386!GO:0031543;peptidyl-proline dioxygenase activity;0.00606559282100801!GO:0006289;nucleotide-excision repair;0.00616611506620361!GO:0051052;regulation of DNA metabolic process;0.00621292443264255!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00646808425291282!GO:0006354;RNA elongation;0.00651025024687784!GO:0006401;RNA catabolic process;0.00653790669062034!GO:0006352;transcription initiation;0.00662771131015669!GO:0045892;negative regulation of transcription, DNA-dependent;0.00670793726412673!GO:0016197;endosome transport;0.00670842556925864!GO:0030660;Golgi-associated vesicle membrane;0.00690635973791479!GO:0007264;small GTPase mediated signal transduction;0.00709347619559801!GO:0051540;metal cluster binding;0.00718308083486411!GO:0051536;iron-sulfur cluster binding;0.00718308083486411!GO:0005869;dynactin complex;0.00726628675590415!GO:0019206;nucleoside kinase activity;0.00730182986548639!GO:0048468;cell development;0.00733016526878881!GO:0008047;enzyme activator activity;0.00749975793935423!GO:0006650;glycerophospholipid metabolic process;0.00761060097766183!GO:0051128;regulation of cellular component organization and biogenesis;0.00799212141767315!GO:0000049;tRNA binding;0.00812588244751304!GO:0016251;general RNA polymerase II transcription factor activity;0.00833230008931456!GO:0007059;chromosome segregation;0.00838152320547722!GO:0006268;DNA unwinding during replication;0.00853776856231077!GO:0031323;regulation of cellular metabolic process;0.0085687321121717!GO:0003702;RNA polymerase II transcription factor activity;0.00873714911721897!GO:0016272;prefoldin complex;0.00874722772381914!GO:0006892;post-Golgi vesicle-mediated transport;0.0089410082147964!GO:0006405;RNA export from nucleus;0.00899466795129907!GO:0006007;glucose catabolic process;0.00900745460602483!GO:0031418;L-ascorbic acid binding;0.00936687608260793!GO:0043433;negative regulation of transcription factor activity;0.00936687608260793!GO:0005862;muscle thin filament tropomyosin;0.00936687608260793!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00948809599924085!GO:0004674;protein serine/threonine kinase activity;0.00963028139570776!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00964195221633326!GO:0019798;procollagen-proline dioxygenase activity;0.00964195221633326!GO:0007017;microtubule-based process;0.00969503258852165!GO:0044433;cytoplasmic vesicle part;0.0100238102509867!GO:0004527;exonuclease activity;0.01002803065425!GO:0032984;macromolecular complex disassembly;0.0100295894920289!GO:0045941;positive regulation of transcription;0.0102081983174508!GO:0000339;RNA cap binding;0.0104530742180666!GO:0005876;spindle microtubule;0.0106309413298194!GO:0045893;positive regulation of transcription, DNA-dependent;0.0107180080568199!GO:0065009;regulation of a molecular function;0.0110343149192794!GO:0006310;DNA recombination;0.0114080354295155!GO:0016044;membrane organization and biogenesis;0.0114122394381767!GO:0005832;chaperonin-containing T-complex;0.011774990877805!GO:0008022;protein C-terminus binding;0.0119063711038948!GO:0051287;NAD binding;0.0119977424762028!GO:0005637;nuclear inner membrane;0.0120025845245484!GO:0030027;lamellipodium;0.0122601462867784!GO:0009116;nucleoside metabolic process;0.0123165859522815!GO:0046467;membrane lipid biosynthetic process;0.0123165859522815!GO:0050681;androgen receptor binding;0.0124681316897507!GO:0006509;membrane protein ectodomain proteolysis;0.0125569050931456!GO:0033619;membrane protein proteolysis;0.0125569050931456!GO:0006497;protein amino acid lipidation;0.0128743084437243!GO:0043022;ribosome binding;0.0130043949498119!GO:0004177;aminopeptidase activity;0.0135385987434618!GO:0043624;cellular protein complex disassembly;0.0136046715019877!GO:0006950;response to stress;0.0136510619268527!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0138339295063613!GO:0016408;C-acyltransferase activity;0.0138382432589382!GO:0007021;tubulin folding;0.0139299007082036!GO:0006740;NADPH regeneration;0.0140627164955212!GO:0006098;pentose-phosphate shunt;0.0140627164955212!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0140627164955212!GO:0015002;heme-copper terminal oxidase activity;0.0140627164955212!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0140627164955212!GO:0004129;cytochrome-c oxidase activity;0.0140627164955212!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0142286780262992!GO:0030384;phosphoinositide metabolic process;0.0142872314909353!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0144454295331501!GO:0045792;negative regulation of cell size;0.0149656323247006!GO:0008632;apoptotic program;0.0150325029288757!GO:0030041;actin filament polymerization;0.0151771623631869!GO:0006984;ER-nuclear signaling pathway;0.0154955807997659!GO:0006611;protein export from nucleus;0.0161141724575501!GO:0031529;ruffle organization and biogenesis;0.0162827587824535!GO:0019752;carboxylic acid metabolic process;0.016282838757066!GO:0043241;protein complex disassembly;0.0167677264219675!GO:0004003;ATP-dependent DNA helicase activity;0.0168574698866098!GO:0006778;porphyrin metabolic process;0.0169507645643323!GO:0033013;tetrapyrrole metabolic process;0.0169507645643323!GO:0006350;transcription;0.016969913151073!GO:0050662;coenzyme binding;0.0170359376950169!GO:0048518;positive regulation of biological process;0.0170512368429326!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0174988812092885!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0174988812092885!GO:0030308;negative regulation of cell growth;0.0175245080144119!GO:0006220;pyrimidine nucleotide metabolic process;0.0176521222782848!GO:0006144;purine base metabolic process;0.0176891204162393!GO:0008168;methyltransferase activity;0.0178009814934785!GO:0016741;transferase activity, transferring one-carbon groups;0.0179072015397332!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0180444374254715!GO:0006082;organic acid metabolic process;0.0184098015682592!GO:0050811;GABA receptor binding;0.0185748666756346!GO:0030833;regulation of actin filament polymerization;0.0187646605647871!GO:0031123;RNA 3'-end processing;0.01882013010405!GO:0006506;GPI anchor biosynthetic process;0.0193244328227568!GO:0030119;AP-type membrane coat adaptor complex;0.0194914061935381!GO:0030125;clathrin vesicle coat;0.0195451936954368!GO:0030665;clathrin coated vesicle membrane;0.0195451936954368!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0198596260581541!GO:0030496;midbody;0.0202071483679963!GO:0000922;spindle pole;0.0202470110490641!GO:0042168;heme metabolic process;0.020323358299546!GO:0016126;sterol biosynthetic process;0.0210109056811507!GO:0051539;4 iron, 4 sulfur cluster binding;0.0211901746783362!GO:0003779;actin binding;0.0217463751246261!GO:0006520;amino acid metabolic process;0.02200780960209!GO:0031625;ubiquitin protein ligase binding;0.022395723726021!GO:0022890;inorganic cation transmembrane transporter activity;0.0226905250059389!GO:0006284;base-excision repair;0.0227692836201379!GO:0000209;protein polyubiquitination;0.0227938036622476!GO:0001527;microfibril;0.022935959944471!GO:0012506;vesicle membrane;0.0233318051786929!GO:0035035;histone acetyltransferase binding;0.023772880671853!GO:0043492;ATPase activity, coupled to movement of substances;0.0238169995156224!GO:0008652;amino acid biosynthetic process;0.0238805686684787!GO:0008154;actin polymerization and/or depolymerization;0.0240987361355303!GO:0005758;mitochondrial intermembrane space;0.024210613617155!GO:0008538;proteasome activator activity;0.0253890173223356!GO:0007034;vacuolar transport;0.0267871045257304!GO:0005669;transcription factor TFIID complex;0.0270838291245849!GO:0006505;GPI anchor metabolic process;0.027325466641596!GO:0035267;NuA4 histone acetyltransferase complex;0.0273294798821592!GO:0005096;GTPase activator activity;0.0275478471285382!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.0280971266591606!GO:0047485;protein N-terminus binding;0.0281929314782541!GO:0001725;stress fiber;0.028302450389835!GO:0032432;actin filament bundle;0.028302450389835!GO:0031902;late endosome membrane;0.0285956595661919!GO:0000792;heterochromatin;0.0285956595661919!GO:0008320;protein transmembrane transporter activity;0.0288068131489053!GO:0051101;regulation of DNA binding;0.0290974995227186!GO:0031901;early endosome membrane;0.0297038335264998!GO:0006378;mRNA polyadenylation;0.0297561730321097!GO:0030131;clathrin adaptor complex;0.0297723550683158!GO:0009303;rRNA transcription;0.0298963804836264!GO:0008610;lipid biosynthetic process;0.0299314968836629!GO:0000228;nuclear chromosome;0.0309155585269465!GO:0030032;lamellipodium biogenesis;0.0314071847118361!GO:0003756;protein disulfide isomerase activity;0.0314597488334237!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0314597488334237!GO:0043189;H4/H2A histone acetyltransferase complex;0.0314832648063244!GO:0030508;thiol-disulfide exchange intermediate activity;0.0320755822485404!GO:0043596;nuclear replication fork;0.0323713232731288!GO:0009124;nucleoside monophosphate biosynthetic process;0.0328943342451027!GO:0009123;nucleoside monophosphate metabolic process;0.0328943342451027!GO:0042158;lipoprotein biosynthetic process;0.0332259450717047!GO:0007040;lysosome organization and biogenesis;0.0334773319673057!GO:0000096;sulfur amino acid metabolic process;0.0337532408294649!GO:0003923;GPI-anchor transamidase activity;0.0338600169620643!GO:0016255;attachment of GPI anchor to protein;0.0338600169620643!GO:0042765;GPI-anchor transamidase complex;0.0338600169620643!GO:0046426;negative regulation of JAK-STAT cascade;0.0340960507219096!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0342885761416372!GO:0022408;negative regulation of cell-cell adhesion;0.0343317865789775!GO:0005784;translocon complex;0.034692098745375!GO:0051098;regulation of binding;0.0352413163293024!GO:0000118;histone deacetylase complex;0.0355321718425961!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0356340560496613!GO:0030518;steroid hormone receptor signaling pathway;0.0357742354543882!GO:0006275;regulation of DNA replication;0.0357742354543882!GO:0031371;ubiquitin conjugating enzyme complex;0.0357742354543882!GO:0045936;negative regulation of phosphate metabolic process;0.0357742354543882!GO:0009967;positive regulation of signal transduction;0.0372344654128031!GO:0005583;fibrillar collagen;0.0374924156387027!GO:0006376;mRNA splice site selection;0.0376188435361439!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0376188435361439!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0381857143931564!GO:0033043;regulation of organelle organization and biogenesis;0.0381857143931564!GO:0031272;regulation of pseudopodium formation;0.0383132215449428!GO:0031269;pseudopodium formation;0.0383132215449428!GO:0031344;regulation of cell projection organization and biogenesis;0.0383132215449428!GO:0031268;pseudopodium organization and biogenesis;0.0383132215449428!GO:0031346;positive regulation of cell projection organization and biogenesis;0.0383132215449428!GO:0031274;positive regulation of pseudopodium formation;0.0383132215449428!GO:0048144;fibroblast proliferation;0.0384449773763754!GO:0048145;regulation of fibroblast proliferation;0.0384449773763754!GO:0007346;regulation of progression through mitotic cell cycle;0.039191438982171!GO:0004518;nuclease activity;0.0394807703105057!GO:0051271;negative regulation of cell motility;0.0402646214723953!GO:0033559;unsaturated fatty acid metabolic process;0.0404290981031748!GO:0006636;unsaturated fatty acid biosynthetic process;0.0404290981031748!GO:0009119;ribonucleoside metabolic process;0.0409066985216393!GO:0032940;secretion by cell;0.0413627422577244!GO:0006779;porphyrin biosynthetic process;0.0413627422577244!GO:0033014;tetrapyrrole biosynthetic process;0.0413627422577244!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0413627422577244!GO:0010257;NADH dehydrogenase complex assembly;0.0413627422577244!GO:0033108;mitochondrial respiratory chain complex assembly;0.0413627422577244!GO:0008601;protein phosphatase type 2A regulator activity;0.0415661745327817!GO:0043065;positive regulation of apoptosis;0.0424997463755183!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.0433379409424934!GO:0030433;ER-associated protein catabolic process;0.0435744035560401!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0435744035560401!GO:0016584;nucleosome positioning;0.0442007321566278!GO:0009262;deoxyribonucleotide metabolic process;0.0446404459857052!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0451758630255968!GO:0007033;vacuole organization and biogenesis;0.0455212831192261!GO:0005856;cytoskeleton;0.0462587240421905!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0462665947451832!GO:0008283;cell proliferation;0.0467590935676968!GO:0018193;peptidyl-amino acid modification;0.0467590935676968!GO:0000178;exosome (RNase complex);0.0469623593319406!GO:0010468;regulation of gene expression;0.0469801262755464!GO:0006338;chromatin remodeling;0.0477107856549553!GO:0048146;positive regulation of fibroblast proliferation;0.0477107856549553!GO:0030911;TPR domain binding;0.0477107856549553!GO:0005801;cis-Golgi network;0.0477107856549553!GO:0004656;procollagen-proline 4-dioxygenase activity;0.0477107856549553!GO:0031545;peptidyl-proline 4-dioxygenase activity;0.0477107856549553!GO:0043068;positive regulation of programmed cell death;0.0489159542973007!GO:0033673;negative regulation of kinase activity;0.0493059111540608!GO:0006469;negative regulation of protein kinase activity;0.0493059111540608!GO:0016860;intramolecular oxidoreductase activity;0.0495054490380994!GO:0006783;heme biosynthetic process;0.0499924134510266!GO:0004448;isocitrate dehydrogenase activity;0.0499924134510266 | |||
|sample_id=11554 | |||
|sample_note= | |||
|sample_sex=M | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=skin | |||
|top_motifs=SRF:1.42197058416;HAND1,2:1.37254050216;HES1:1.30935337992;FOXL1:1.20871343224;NR3C1:1.1058265773;GCM1,2:1.07296940015;GZF1:1.0339685021;ALX4:1.03381185073;HOX{A5,B5}:1.03136473653;KLF4:1.0262398141;TEAD1:1.00959608225;ZNF238:0.959486041475;GFI1:0.930346002815;NFIX:0.869940242544;GTF2A1,2:0.863006063684;MYBL2:0.859508866725;TP53:0.841304620604;EBF1:0.827423546793;HSF1,2:0.815718642234;NKX2-2,8:0.814891244497;HBP1_HMGB_SSRP1_UBTF:0.766630988361;CDC5L:0.711604933525;UFEwm:0.70931380392;EN1,2:0.703373032021;ESR1:0.703123458886;GFI1B:0.665421789227;NKX3-1:0.660852723074;TFDP1:0.65403227733;GLI1..3:0.641076070179;ZIC1..3:0.632301318321;PDX1:0.628414416899;IKZF1:0.611346811701;MYB:0.585217736373;HMGA1,2:0.561421800805;NFE2L1:0.557501066264;GTF2I:0.545851234214;HIF1A:0.545760131571;GATA4:0.542873972081;PAX1,9:0.528701572524;ZNF384:0.528109743868;TFAP4:0.523493068349;PAX3,7:0.516185654276;TAL1_TCF{3,4,12}:0.513585049049;XCPE1{core}:0.51171774408;TBX4,5:0.505332016907;ZBTB6:0.475388696335;TLX1..3_NFIC{dimer}:0.474501585809;SOX17:0.473090051734;LHX3,4:0.461669148685;PRDM1:0.440425026803;MZF1:0.438156583792;NFE2L2:0.436023634843;LEF1_TCF7_TCF7L1,2:0.435588531953;RXR{A,B,G}:0.409005719607;E2F1..5:0.405369326482;MAZ:0.387264840499;TFAP2{A,C}:0.382220036577;TBP:0.379446244824;ELK1,4_GABP{A,B1}:0.376638599682;SMAD1..7,9:0.374926760658;XBP1:0.367358705047;NFATC1..3:0.359150102754;BACH2:0.35477761859;PAX8:0.354153451151;TFCP2:0.347562790728;NKX3-2:0.327161868534;POU5F1:0.323057166148;PRRX1,2:0.320033272028;RXRA_VDR{dimer}:0.309635238437;HMX1:0.288712482771;RREB1:0.279706518318;MTE{core}:0.276195861388;STAT5{A,B}:0.268864878985;ZNF423:0.257192623001;NFY{A,B,C}:0.2539771431;ADNP_IRX_SIX_ZHX:0.245473972287;MEF2{A,B,C,D}:0.232338150385;TFAP2B:0.193351705224;HOX{A4,D4}:0.178435228477;YY1:0.173634590091;FOXQ1:0.172675147782;AHR_ARNT_ARNT2:0.161210825281;ZNF143:0.14129381613;HLF:0.137172955781;FOS_FOS{B,L1}_JUN{B,D}:0.136567313268;ZNF148:0.120349025216;MAFB:0.107994324969;CRX:0.106135719104;NFE2:0.0941320682109;EVI1:0.0918302087326;HOXA9_MEIS1:0.0674193329513;NRF1:0.0653516164746;SOX{8,9,10}:0.0487419946455;FOSL2:0.0242489742682;POU2F1..3:0.0223501889744;AIRE:0.0119151405483;ATF6:-0.00440416539314;TOPORS:-0.0144873153198;NANOG{mouse}:-0.0188502220947;PBX1:-0.0363018637585;HIC1:-0.0398856515665;SPZ1:-0.0425189164237;PATZ1:-0.0485643673605;NKX2-3_NKX2-5:-0.0533621907677;NR6A1:-0.0560439664289;JUN:-0.066222543269;HNF1A:-0.0664638631864;NHLH1,2:-0.0703755591496;SOX5:-0.0832333030162;SP1:-0.0841258963387;FOXM1:-0.11219133229;POU3F1..4:-0.12058572139;ESRRA:-0.123461742858;PPARG:-0.123534508515;CEBPA,B_DDIT3:-0.13138531437;MTF1:-0.142108231566;RFX1:-0.147327280253;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.151107717759;SOX2:-0.161717238173;NKX6-1,2:-0.166913331492;HNF4A_NR2F1,2:-0.171897406039;POU1F1:-0.179030281303;FOX{I1,J2}:-0.194298685188;OCT4_SOX2{dimer}:-0.195231867182;NR1H4:-0.196111755539;DMAP1_NCOR{1,2}_SMARC:-0.204618758108;RUNX1..3:-0.226011906988;MYFfamily:-0.230089275344;PAX5:-0.238596467467;EP300:-0.239748806157;REST:-0.24065194614;FOXD3:-0.247873700596;FOXO1,3,4:-0.254391693234;NR5A1,2:-0.259007688752;TEF:-0.262008960466;HOX{A6,A7,B6,B7}:-0.267925415731;FOXA2:-0.268943375753;MED-1{core}:-0.292659535352;STAT2,4,6:-0.293537037899;PAX4:-0.294251900416;T:-0.309422693169;IRF1,2:-0.315948824412;ARID5B:-0.318711982514;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.33937519755;VSX1,2:-0.343014722235;EGR1..3:-0.346302706976;TGIF1:-0.354697317168;AR:-0.375217901;ELF1,2,4:-0.375487618223;STAT1,3:-0.380133777954;FOXP3:-0.383032775528;PITX1..3:-0.387588070139;NANOG:-0.398510464179;ETS1,2:-0.40125549634;NFKB1_REL_RELA:-0.41075560564;ALX1:-0.419381728608;SPI1:-0.437008540298;bHLH_family:-0.461741654476;GATA6:-0.46816369156;ZFP161:-0.468645378122;RBPJ:-0.470456849864;NFIL3:-0.505222330793;LMO2:-0.5158707428;ATF5_CREB3:-0.517790529238;ONECUT1,2:-0.521737541732;SPIB:-0.527540070939;BREu{core}:-0.532602132213;CUX2:-0.596290299735;BPTF:-0.599804019465;SNAI1..3:-0.611985734395;PAX2:-0.657699635583;POU6F1:-0.661612067833;DBP:-0.672903860545;ATF4:-0.677855407276;FOX{D1,D2}:-0.714224652486;FOXN1:-0.719650018926;IRF7:-0.73207313786;CREB1:-0.739654857705;PAX6:-0.746408198611;CDX1,2,4:-0.764539216046;NKX2-1,4:-0.815093215006;RFX2..5_RFXANK_RFXAP:-0.825315907039;FOXP1:-0.852677106796;ZEB1:-0.861428965126;SREBF1,2:-0.903349582237;FOX{F1,F2,J1}:-0.964403738014;IKZF2:-0.979962211958;ATF2:-1.04973811408;MYOD1:-1.0942355285;TLX2:-1.16885732192;RORA:-1.22099495908;ZBTB16:-1.31985586848 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11554-120C6;search_select_hide=table117:FF:11554-120C6 | |||
}} | }} |
Latest revision as of 18:08, 4 June 2020
Name: | Fibroblast - skin walker warburg, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11352 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11352
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11352
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.314 |
10 | 10 | 0.385 |
100 | 100 | 0.994 |
101 | 101 | 0.459 |
102 | 102 | 0.16 |
103 | 103 | 0.952 |
104 | 104 | 0.922 |
105 | 105 | 0.938 |
106 | 106 | 0.79 |
107 | 107 | 0.45 |
108 | 108 | 0.818 |
109 | 109 | 0.299 |
11 | 11 | 0.691 |
110 | 110 | 0.277 |
111 | 111 | 0.341 |
112 | 112 | 0.984 |
113 | 113 | 0.0337 |
114 | 114 | 0.784 |
115 | 115 | 0.583 |
116 | 116 | 0.171 |
117 | 117 | 0.416 |
118 | 118 | 0.745 |
119 | 119 | 0.681 |
12 | 12 | 0.851 |
120 | 120 | 0.744 |
121 | 121 | 0.323 |
122 | 122 | 0.775 |
123 | 123 | 1.63445e-5 |
124 | 124 | 0.837 |
125 | 125 | 0.709 |
126 | 126 | 0.398 |
127 | 127 | 0.896 |
128 | 128 | 0.997 |
129 | 129 | 0.962 |
13 | 13 | 0.775 |
130 | 130 | 0.0446 |
131 | 131 | 0.46 |
132 | 132 | 0.452 |
133 | 133 | 0.442 |
134 | 134 | 0.28 |
135 | 135 | 0.229 |
136 | 136 | 0.291 |
137 | 137 | 0.26 |
138 | 138 | 0.21 |
139 | 139 | 0.0156 |
14 | 14 | 0.274 |
140 | 140 | 0.212 |
141 | 141 | 0.0391 |
142 | 142 | 0.899 |
143 | 143 | 0.583 |
144 | 144 | 0.9 |
145 | 145 | 0.48 |
146 | 146 | 0.888 |
147 | 147 | 0.0974 |
148 | 148 | 0.0844 |
149 | 149 | 0.0842 |
15 | 15 | 0.251 |
150 | 150 | 0.362 |
151 | 151 | 0.939 |
152 | 152 | 0.053 |
153 | 153 | 0.868 |
154 | 154 | 0.477 |
155 | 155 | 0.0118 |
156 | 156 | 0.765 |
157 | 157 | 0.0475 |
158 | 158 | 0.00556 |
159 | 159 | 0.522 |
16 | 16 | 0.187 |
160 | 160 | 0.303 |
161 | 161 | 0.353 |
162 | 162 | 0.396 |
163 | 163 | 0.866 |
164 | 164 | 0.412 |
165 | 165 | 0.228 |
166 | 166 | 0.0686 |
167 | 167 | 0.186 |
168 | 168 | 0.733 |
169 | 169 | 0.0664 |
17 | 17 | 0.714 |
18 | 18 | 0.121 |
19 | 19 | 0.0269 |
2 | 2 | 0.345 |
20 | 20 | 0.182 |
21 | 21 | 0.162 |
22 | 22 | 0.215 |
23 | 23 | 0.612 |
24 | 24 | 0.975 |
25 | 25 | 0.856 |
26 | 26 | 0.72 |
27 | 27 | 0.71 |
28 | 28 | 0.232 |
29 | 29 | 0.747 |
3 | 3 | 0.98 |
30 | 30 | 0.035 |
31 | 31 | 0.945 |
32 | 32 | 2.1789e-5 |
33 | 33 | 0.999 |
34 | 34 | 0.66 |
35 | 35 | 0.355 |
36 | 36 | 0.074 |
37 | 37 | 0.229 |
38 | 38 | 0.613 |
39 | 39 | 0.477 |
4 | 4 | 0.495 |
40 | 40 | 0.889 |
41 | 41 | 0.68 |
42 | 42 | 0.951 |
43 | 43 | 0.924 |
44 | 44 | 0.954 |
45 | 45 | 0.437 |
46 | 46 | 0.616 |
47 | 47 | 0.882 |
48 | 48 | 0.843 |
49 | 49 | 0.463 |
5 | 5 | 0.737 |
50 | 50 | 0.262 |
51 | 51 | 0.997 |
52 | 52 | 0.899 |
53 | 53 | 0.381 |
54 | 54 | 0.681 |
55 | 55 | 0.866 |
56 | 56 | 0.93 |
57 | 57 | 0.665 |
58 | 58 | 0.323 |
59 | 59 | 0.0952 |
6 | 6 | 0.905 |
60 | 60 | 0.562 |
61 | 61 | 0.242 |
62 | 62 | 0.779 |
63 | 63 | 0.559 |
64 | 64 | 0.885 |
65 | 65 | 0.695 |
66 | 66 | 0.224 |
67 | 67 | 0.859 |
68 | 68 | 0.844 |
69 | 69 | 0.434 |
7 | 7 | 0.626 |
70 | 70 | 0.0388 |
71 | 71 | 0.474 |
72 | 72 | 0.982 |
73 | 73 | 0.0575 |
74 | 74 | 0.365 |
75 | 75 | 0.715 |
76 | 76 | 0.128 |
77 | 77 | 0.0128 |
78 | 78 | 0.125 |
79 | 79 | 0.0659 |
8 | 8 | 0.607 |
80 | 80 | 0.965 |
81 | 81 | 0.882 |
82 | 82 | 0.85 |
83 | 83 | 0.192 |
84 | 84 | 0.494 |
85 | 85 | 0.418 |
86 | 86 | 0.801 |
87 | 87 | 0.178 |
88 | 88 | 0.416 |
89 | 89 | 0.0758 |
9 | 9 | 0.429 |
90 | 90 | 0.0564 |
91 | 91 | 0.822 |
92 | 92 | 0.977 |
93 | 93 | 0.183 |
94 | 94 | 0.562 |
95 | 95 | 0.194 |
96 | 96 | 0.64 |
97 | 97 | 0.832 |
98 | 98 | 0.288 |
99 | 99 | 8.93986e-4 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11352
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000252 human fibroblast - skin walker warburg sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
0000057 (fibroblast)
0002620 (skin fibroblast)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002097 (skin of body)
0002199 (integument)
0002384 (connective tissue)
0000479 (tissue)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0003102 (surface structure)
0002416 (integumental system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000057 (fibroblast sample)
0000250 (human fibroblast of skin sample)
0000001 (sample)
0000252 (human fibroblast - skin walker warburg sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)