FF:11860-125A6: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004938 | ||
| | |accession_numbers=CAGE;DRX008138;DRR009010;DRZ000435;DRZ001820;DRZ011785;DRZ013170 | ||
| | |ancestors_in_anatomy_facet= | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000766,CL:0000219,CL:0000325,CL:0000473,CL:0000234,CL:0000738,CL:0002087,CL:0000255,CL:0000576,CL:0000860,CL:0002057 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000628,FF:0011103 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr2:68592406..68592424,+!p1@PLEK!3.90!7988.93!PLEK;;chr16:85932760..85932775,+!p1@IRF8!2.96!914.57!IRF8;;chr11:47400078..47400106,-!p1@SPI1!2.76!579.12!SPI1;;chr10:64576105..64576133,-!p1@EGR2!2.73!1058.42!EGR2;;chr10:35484053..35484076,+!p1@CREM!2.68!1133.80!CREM;;chr12:54778471..54778528,-!p1@ZNF385A!2.55!356.16!ZNF385A;;chr7:115670804..115670825,-!p1@TFEC!2.45!282.23!TFEC;;chr20:39317868..39317884,-!p1@MAFB!2.26!1987.09!MAFB;;chr11:64764435..64764449,-!p1@BATF2!2.23!230.15!BATF2;;chr2:70142232..70142251,+!p1@MXD1!2.22!867.10!MXD1;;chr6:106534192..106534224,+!p1@PRDM1!2.19!416.00!PRDM1;;chr6:36355431..36355466,-!p1@ETV7!2.12!130.32!ETV7;;chr7:128577972..128578047,+!p1@IRF5!2.11!195.92!IRF5;;chr11:47399947..47399961,-!p3@SPI1!2.11!127.45!SPI1;;chr11:47400062..47400077,-!p2@SPI1!2.09!121.41!SPI1;;chr11:65430554..65430579,-!p3@RELA!2.07!286.83!RELA;;chr5:131826457..131826514,-!p1@IRF1!2.06!4125.22!IRF1;;chr2:68592394..68592405,+!p2@PLEK!2.03!105.30!PLEK;;chr17:45810594..45810608,+!p1@TBX21!1.96!89.76!TBX21;;chr11:615942..615957,-!p1@IRF7!1.95!781.95!IRF7;;chr1:221052776..221052799,+!p1@HLX!1.94!150.18!HLX;;chr1:25256756..25256774,-!p1@RUNX3!1.93!153.34!RUNX3;;chr10:35484090..35484104,+!p6@CREM!1.93!84.87!CREM;;chr11:65430535..65430549,-!p4@RELA!1.91!91.77!RELA;;chr21:36260295..36260310,-!p3@RUNX1!1.90!123.42!RUNX1;;chr11:47399996..47400014,-!p4@SPI1!1.87!73.94!SPI1;;chr6:106534230..106534254,+!p2@PRDM1!1.83!161.40!PRDM1;;chr16:31885093..31885165,+!p1@ZNF267!1.81!904.79!ZNF267;;chr1:158985493..158985535,+!p4@IFI16!1.81!94.08!IFI16;;chr12:72056800..72056834,+!p1@THAP2!1.80!83.14!THAP2;;chr19:50432132..50432217,+!p2@ATF5!1.80!73.36!ATF5;;chr14:35872453..35872485,-!p2@NFKBIA!1.79!144.42!NFKBIA;;chr2:231084639..231084654,-!p2@SP110!1.79!97.53!SP110;;chr14:75988831..75988847,+!p2@BATF!1.77!57.54!BATF;;chr10:31288398..31288455,-!p2@ZNF438!1.75!63.58!ZNF438;;chr12:72056749..72056767,+!p6@THAP2!1.75!61.57!THAP2;;chr19:36391434..36391450,-!p1@NFKBID!1.74!102.13!NFKBID;;chr22:38597987..38598021,+!p2@MAFF!1.73!307.83!MAFF;;chr11:47400032..47400043,-!p5@SPI1!1.73!53.22!SPI1;;chr1:212782094..212782109,+!p1@ATF3!1.72!1320.22!ATF3;;chr10:64018918..64018936,+!p2@ZNF365!1.72!51.78!ZNF365;;chr14:35873947..35873965,-!p1@NFKBIA!1.69!2856.50!NFKBIA;;chr2:145277640..145277771,-!p1@ZEB2!1.69!607.32!ZEB2;;chr19:45971246..45971265,+!p1@FOSB!1.68!831.14!FOSB;;chr21:30671690..30671762,+!p2@BACH1!1.68!153.34!BACH1;;chr11:615570..615721,-!p2@IRF7!1.67!88.32!IRF7;;chr2:97202480..97202499,+!p1@ARID5A!1.66!425.50!ARID5A;;chr2:145275162..145275202,-!p2@ZEB2!1.66!251.73!ZEB2;;chr1:221052733..221052749,+!p2@HLX!1.66!58.11!HLX;;chr10:35484804..35484902,+!p2@CREM!1.63!151.90!CREM;;chr8:22550982..22550999,-!p1@EGR3!1.63!113.06!EGR3;;chr10:51572408..51572454,+!p3@NCOA4!1.61!221.52!NCOA4;;chr3:12329397..12329433,+!p2@PPARG!1.61!88.90!PPARG;;chr2:231090471..231090504,+!p2@SP140!1.61!39.70!SP140;;chr14:75988771..75988826,+!p1@BATF!1.59!50.06!BATF;;chr12:54778351..54778378,-!p6@ZNF385A!1.58!37.40!ZNF385A;;chr1:158979872..158979898,+!p3@IFI16!1.56!105.58!IFI16;;chr4:185395590..185395627,-!p3@IRF2!1.56!43.15!IRF2;;chr6:126240380..126240430,+!p2@NCOA7!1.55!87.17!NCOA7;;chr21:30671235..30671253,+!p1@BACH1!1.54!411.40!BACH1;;chr2:157189180..157189290,-!p1@NR4A2!1.54!168.59!NR4A2;;chr12:72056773..72056796,+!p3@THAP2!1.54!43.44!THAP2;;chr10:31288370..31288393,-!p3@ZNF438!1.54!33.37!ZNF438;;chr21:34442439..34442455,+!p1@OLIG1!1.53!32.80!OLIG1;;chr19:33793430..33793447,-!p1@CEBPA!1.49!121.98!CEBPA;;chr10:51572339..51572376,+!p4@NCOA4!1.49!66.46!NCOA4;;chr4:185395633..185395651,-!p2@IRF2!1.48!46.32!IRF2;;chr2:70167296..70167306,+!p3@MXD1!1.48!43.73!MXD1;;chr3:39195037..39195069,-!p2@CSRNP1!1.47!170.31!CSRNP1;;chr4:103422499..103422632,+!p1@NFKB1!1.46!556.40!NFKB1;;chr16:79634624..79634642,-!p1@MAF!1.46!105.30!MAF;;chr21:36421535..36421610,-!p2@RUNX1!1.46!96.66!RUNX1;;chr14:35872962..35873025,-!p3@NFKBIA!1.46!68.47!NFKBIA;;chrX:153305787..153305807,-!p3@MECP2!1.46!27.91!MECP2;;chrX:129244454..129244488,-!p1@ELF4!1.45!189.01!ELF4;;chr21:36260343..36260402,-!p6@RUNX1!1.45!43.44!RUNX1;;chr6:106535598..106535637,+!p7@PRDM1!1.45!27.04!PRDM1;;chr2:145277882..145277967,-!p3@ZEB2!1.44!44.88!ZEB2;;chr11:47399920..47399931,-!p7@SPI1!1.44!26.76!SPI1;;chr10:104155480..104155534,+!p2@NFKB2!1.43!161.68!NFKB2;;chr6:15246200..15246214,+!p2@JARID2!1.43!69.33!JARID2;;chr12:48298765..48298783,-!p2@VDR!1.43!52.65!VDR;;chr6:144385698..144385742,-!p2@PLAGL1!1.43!31.07!PLAGL1;;chr2:191885737..191885750,-!p4@STAT1!1.43!25.89!STAT1;;chr7:50344289..50344323,+!p1@IKZF1!1.42!25.03!IKZF1;;chr3:101568349..101568365,+!p1@NFKBIZ!1.41!1216.08!NFKBIZ;;chr11:47400045..47400060,-!p6@SPI1!1.41!24.74!SPI1;;chr3:187455680..187455700,-!p4@BCL6!1.41!24.45!BCL6;;chr13:41593425..41593480,-!p1@ELF1!1.40!149.89!ELF1;;chr9:102584159..102584174,+!p2@NR4A3!1.40!43.15!NR4A3;;chr19:45251395..45251432,+!p8@BCL3!1.40!24.17!BCL3;;chr12:11802753..11802834,+!p2@ETV6!1.39!111.34!ETV6;;chr3:39195139..39195150,-!p3@CSRNP1!1.39!29.92!CSRNP1;;chr17:38497662..38497713,+!p4@RARA!1.39!27.33!RARA;;chr10:64575812..64575824,-!p4@EGR2!1.39!23.59!EGR2;;chr6:391743..391759,+!p1@IRF4!1.39!23.59!IRF4;;chr20:48807351..48807384,+!p1@CEBPB!1.38!2245.73!CEBPB;;chr9:102584262..102584276,+!p1@NR4A3!1.38!50.06!NR4A3;;chr3:187463179..187463201,-!p2@BCL6!1.37!90.05!BCL6;;chr19:45252008..45252024,+!p2@BCL3!1.37!71.64!BCL3;;chr1:38325227..38325246,-!p2@MTF1!1.37!30.78!MTF1;;chr9:110252035..110252057,-!p1@KLF4!1.36!340.92!KLF4;;chr12:56415246..56415286,+!p2@IKZF4!1.36!21.86!IKZF4;;chr6:44233252..44233296,-!p1@NFKBIE!1.35!205.70!NFKBIE;;chr8:116681123..116681143,-!p4@TRPS1!1.35!40.56!TRPS1;;chr22:38598086..38598105,+!p1@MAFF!1.34!216.63!MAFF;;chr2:61108695..61108753,+!p1@REL!1.34!140.39!REL;;chr3:12330560..12330579,+!p1@PPARG!1.34!24.17!PPARG;;chr21:40177845..40177863,+!p1@ETS2!1.33!1157.10!ETS2;;chr10:104154246..104154347,+!p3@NFKB2!1.33!120.83!NFKB2;;chr22:38598057..38598071,+!p3@MAFF!1.33!46.89!MAFF;;chr6:126240442..126240459,+!p4@NCOA7!1.33!25.89!NCOA7;;chr9:110250697..110250738,-!p2@KLF4!1.33!23.88!KLF4;;chr21:36260325..36260341,-!p14@RUNX1!1.33!20.14!RUNX1;;chr4:106068026..106068084,+!p1@TET2!1.32!174.92!TET2;;chr14:35872494..35872511,-!p5@NFKBIA!1.32!26.18!NFKBIA;;chr21:30672433..30672464,+!p6@BACH1!1.32!19.85!BACH1;;chr18:3449720..3449749,+!p2@TGIF1!1.31!40.85!TGIF1;;chr2:145275228..145275241,-!p11@ZEB2!1.31!23.30!ZEB2;;chr3:187455634..187455651,-!p7@BCL6!1.31!19.28!BCL6;;chr2:70314240..70314256,+!p4@PCBP1!1.30!38.26!PCBP1;;chr5:142782823..142782854,-!p3@NR3C1!1.30!26.76!NR3C1;;chr1:221052840..221052875,+!p4@HLX!1.30!22.44!HLX;;chr21:30672734..30672748,+!p11@BACH1!1.30!18.99!BACH1;;chr1:37940170..37940190,+!p1@ZC3H12A!1.29!222.67!ZC3H12A;;chr9:102584128..102584144,+!p3@NR4A3!1.29!35.10!NR4A3;;chr6:126240463..126240489,+!p6@NCOA7!1.29!20.71!NCOA7;;chr2:231090433..231090469,+!p1@SP140!1.29!18.41!SP140;;chrX:129244430..129244442,-!p5@ELF4!1.29!18.41!ELF4;;chrX:2418949..2419024,-!p1@DHRSX,p1@ZBED1!1.28!17.84!ZBED1;;chr14:35872926..35872951,-!p4@NFKBIA!1.26!24.45!NFKBIA;;chr2:192015701..192015743,-!p1@STAT4!1.26!23.59!STAT4;;chr7:115670792..115670797,-!p2@TFEC!1.26!17.26!TFEC;;chr19:45250948..45250998,+!p3@BCL3!1.25!41.72!BCL3;;chr21:36260980..36261011,-!p1@RUNX1!1.24!460.02!RUNX1;;chr2:231084659..231084721,-!p1@SP110!1.23!360.48!SP110;;chr12:52445218..52445237,+!p1@NR4A1!1.23!195.92!NR4A1;;chr10:64576035..64576046,-!p2@EGR2!1.23!15.82!EGR2;;chr1:25256439..25256476,-!p3@RUNX3!1.23!15.82!RUNX3;;chr18:3449586..3449617,+!p8@TGIF1!1.22!24.74!TGIF1;;chr4:103423079..103423112,+!p4@NFKB1!1.22!15.54!NFKB1;;chr9:129567282..129567353,+!p1@ZBTB43!1.21!197.93!ZBTB43;;chr18:3449618..3449634,+!p13@TGIF1!1.21!18.99!TGIF1;;chr1:221052994..221053008,+!p6@HLX!1.21!17.84!HLX;;chr10:104155455..104155479,+!p1@NFKB2!1.20!212.03!NFKB2;;chr3:39195075..39195088,-!p1@CSRNP1!1.20!91.49!CSRNP1;;chr2:231280954..231280965,+!p2@SP100!1.20!27.04!SP100;;chr3:187454281..187454300,-!p8@BCL6!1.20!14.67!BCL6;;chr3:187455486..187455504,-!p6@BCL6!1.19!14.38!BCL6;;chr7:17338266..17338282,+!p1@AHR!1.18!150.18!AHR;;chr20:48599506..48599526,+!p1@SNAI1!1.18!89.76!SNAI1;;chr16:3285119..3285133,-!p2@ZNF200!1.18!28.19!ZNF200;;chr2:28618532..28618610,+!p4@FOSL2!1.18!23.88!FOSL2;;chr3:101546827..101546847,+!p2@NFKBIZ!1.18!20.14!NFKBIZ;;chr4:185395191..185395226,-!p4@IRF2!1.18!19.56!IRF2;;chr10:3827371..3827386,-!p2@KLF6!1.17!114.21!KLF6;;chr16:79634595..79634620,-!p2@MAF!1.16!24.45!MAF;;chr16:89787973..89788001,+!p3@ZNF276!1.15!25.03!ZNF276;;chr4:83822199..83822239,+!p2@THAP9!1.15!15.82!THAP9;;chr11:65430617..65430624,-!p8@RELA!1.15!13.23!RELA;;chr19:12902289..12902307,+!p1@JUNB!1.14!2876.64!JUNB;;chr7:28725740..28725778,+!p1@CREB5!1.14!114.79!CREB5;;chr8:116681409..116681431,-!p2@TRPS1!1.14!35.10!TRPS1;;chr8:116681150..116681164,-!p5@TRPS1!1.14!25.32!TRPS1;;chr1:221053049..221053075,+!p3@HLX!1.14!22.15!HLX;;chr19:45254529..45254561,+!p10@BCL3!1.14!17.26!BCL3;;chr2:145271342..145271377,-!p5@ZEB2!1.14!12.95!ZEB2;;chr11:65430038..65430053,-!p12@RELA!1.14!12.95!RELA;;chr17:79885537..79885554,-!p2@MAFG!1.13!23.88!MAFG;;chr14:35872414..35872425,-!p7@NFKBIA!1.13!14.10!NFKBIA;;chr14:35872542..35872553,-!p10@NFKBIA!1.13!12.37!NFKBIA;;chr1:221054922..221054933,+!p16@HLX!1.13!12.37!HLX;;chr12:48298785..48298828,-!p1@VDR!1.12!65.31!VDR;;chr11:65429891..65429915,-!p7@RELA!1.12!12.08!RELA;;chr7:150946376..150946389,-!p6@SMARCD3!1.12!12.08!SMARCD3;;chr1:158979792..158979814,+!p2@IFI16!1.11!113.06!IFI16;;chr2:70142189..70142223,+!p2@MXD1!1.11!84.01!MXD1;;chr14:74226747..74226779,-!p3@C14orf43!1.11!65.59!C14orf43;;chr10:35416142..35416169,+!p3@CREM!1.11!31.65!CREM;;chr18:3448455..3448480,+!p5@TGIF1!1.11!22.15!TGIF1;;chr18:3449695..3449712,+!p9@TGIF1!1.11!18.12!TGIF1;;chr15:85291372..85291405,+!p3@ZNF592!1.11!16.40!ZNF592;;chr11:65430586..65430593,-!p5@RELA!1.11!13.52!RELA;;chr3:187455529..187455544,-!p5@BCL6!1.11!11.80!BCL6;;chr1:158979922..158979933,+!p13@IFI16!1.11!11.80!IFI1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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000222;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000234;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000576;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000738;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000763;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000766;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000860;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000988;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002193;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002390;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002405 | |||
|ffid_belonging_in_development=CL:0000049,CL:0000134,CL:0002057 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 66: | Line 41: | ||
|fonse_treatment=FF:0000625,FF:0000628,FF:0011103,FF:11860-125A6 | |fonse_treatment=FF:0000625,FF:0000628,FF:0011103,FF:11860-125A6 | ||
|fonse_treatment_closure=FF:0000625,FF:0000628,FF:0011103,FF:11860-125A6 | |fonse_treatment_closure=FF:0000625,FF:0000628,FF:0011103,FF:11860-125A6 | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor1.CNhs13465.11860-125A6.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor1.CNhs13465.11860-125A6.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor1.CNhs13465.11860-125A6.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor1.CNhs13465.11860-125A6.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/CD14%252b%2520monocytes%2520-%2520treated%2520with%2520BCG%252c%2520donor1.CNhs13465.11860-125A6.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11860-125A6 | |||
|is_a=EFO:0002091;;FF:0011103 | |||
|is_obsolete= | |||
|library_id=CNhs13465 | |||
|library_id_phase_based=2:CNhs13465 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11860 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11860 | |||
|name=CD14+ monocytes - treated with BCG, donor1 | |||
|namespace= | |namespace= | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs13465,LSID1024,release012,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |||
|rna_catalog_number= | |||
|rna_concentration=0.82262 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number=D3-1 | |||
|rna_od260/230=1.77 | |||
|rna_od260/280=2.03 | |||
|rna_position=A6 | |||
|rna_rin=9.1 | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=125A6 | |||
|rna_weight_ug=4.1131 | |||
|sample_age=69 | |||
|sample_category=primary cells | |||
|sample_cell_catalog= | |||
|sample_cell_line= | |||
|sample_cell_lot= | |||
|sample_cell_type=monocyte | |||
|sample_collaboration=Christine Wells (University of Queensland) | |||
|sample_company= | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)=donor1 | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;7.67618830377614e-289!GO:0005737;cytoplasm;2.19729333800599e-127!GO:0043227;membrane-bound organelle;1.65796734371754e-108!GO:0043231;intracellular membrane-bound organelle;3.14184231422876e-108!GO:0043226;organelle;5.81369473877556e-99!GO:0043229;intracellular organelle;3.18378816797476e-98!GO:0044444;cytoplasmic part;8.80465264581628e-85!GO:0044422;organelle part;2.37711716647224e-70!GO:0005515;protein binding;1.41863030364396e-69!GO:0044446;intracellular organelle part;8.443946751324e-69!GO:0044237;cellular metabolic process;5.14388267855528e-61!GO:0044238;primary metabolic process;2.23744703124341e-59!GO:0043170;macromolecule metabolic process;3.35645479423336e-56!GO:0032991;macromolecular complex;3.931141601099e-56!GO:0003723;RNA binding;5.75959671694347e-53!GO:0030529;ribonucleoprotein complex;4.36775864158134e-48!GO:0019538;protein metabolic process;6.8636789641389e-48!GO:0044267;cellular protein metabolic process;5.51839011309227e-45!GO:0044260;cellular macromolecule metabolic process;1.14642768155401e-44!GO:0044428;nuclear part;1.44489474864682e-43!GO:0033036;macromolecule localization;1.15624771384474e-42!GO:0015031;protein transport;3.28362439014001e-42!GO:0045184;establishment of protein localization;1.43354353715393e-41!GO:0008104;protein localization;5.23599850831926e-40!GO:0006412;translation;1.54533500810506e-39!GO:0005634;nucleus;2.23426636130175e-39!GO:0031090;organelle membrane;3.70177426656118e-36!GO:0005829;cytosol;6.16365272993845e-36!GO:0043233;organelle lumen;1.29808616026257e-35!GO:0031974;membrane-enclosed lumen;1.29808616026257e-35!GO:0006915;apoptosis;1.22408827978866e-32!GO:0012501;programmed cell death;1.37024615662114e-32!GO:0008219;cell death;1.64967759764193e-31!GO:0016265;death;1.64967759764193e-31!GO:0016071;mRNA metabolic process;1.99748602148753e-30!GO:0009059;macromolecule biosynthetic process;5.90290847351846e-30!GO:0043283;biopolymer metabolic process;8.24726435572895e-29!GO:0043234;protein complex;1.19788513430992e-28!GO:0009058;biosynthetic process;2.05696206319367e-28!GO:0006396;RNA processing;2.1791266399959e-28!GO:0005739;mitochondrion;5.74145411330665e-28!GO:0044249;cellular biosynthetic process;9.18965033523847e-28!GO:0010467;gene expression;3.28638911023686e-27!GO:0006886;intracellular protein transport;4.67297894196362e-27!GO:0031981;nuclear lumen;7.9273304966498e-27!GO:0046907;intracellular transport;1.21563256151359e-26!GO:0008380;RNA splicing;2.07710486649231e-26!GO:0031967;organelle envelope;3.49047574925781e-26!GO:0006397;mRNA processing;3.63927907062912e-26!GO:0031975;envelope;6.47165284558657e-26!GO:0016043;cellular component organization and biogenesis;7.60131817392388e-26!GO:0005840;ribosome;4.20399846796467e-25!GO:0003735;structural constituent of ribosome;2.29577655300943e-23!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.46237488450411e-23!GO:0033279;ribosomal subunit;9.08107510414971e-23!GO:0042981;regulation of apoptosis;8.07177440493376e-22!GO:0002376;immune system process;9.70494582637406e-22!GO:0043067;regulation of programmed cell death;1.83089736776679e-21!GO:0044445;cytosolic part;2.49735342888579e-21!GO:0044429;mitochondrial part;2.56140362132184e-21!GO:0051649;establishment of cellular localization;1.04234707688845e-20!GO:0005681;spliceosome;2.23417079952909e-20!GO:0065003;macromolecular complex assembly;3.73424852997086e-20!GO:0051641;cellular localization;4.94664914749242e-20!GO:0000166;nucleotide binding;8.13417957499962e-20!GO:0008134;transcription factor binding;8.94741960361878e-20!GO:0005654;nucleoplasm;1.39260290731801e-19!GO:0007243;protein kinase cascade;5.57245087563457e-19!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.68256422459202e-19!GO:0016192;vesicle-mediated transport;9.97368347867249e-19!GO:0006512;ubiquitin cycle;4.72759750045926e-18!GO:0006955;immune response;5.12574615945553e-18!GO:0005740;mitochondrial envelope;3.40240058949468e-17!GO:0006119;oxidative phosphorylation;4.48194149858098e-17!GO:0044265;cellular macromolecule catabolic process;4.70104525841648e-17!GO:0007249;I-kappaB kinase/NF-kappaB cascade;8.11353754349904e-17!GO:0031966;mitochondrial membrane;8.88728795097561e-17!GO:0022607;cellular component assembly;1.4238741440881e-16!GO:0043412;biopolymer modification;1.59697268708523e-16!GO:0044451;nucleoplasm part;1.89555793316438e-16!GO:0005773;vacuole;4.68174945658902e-16!GO:0048523;negative regulation of cellular process;4.77343616422993e-16!GO:0048770;pigment granule;5.56322895536689e-16!GO:0042470;melanosome;5.56322895536689e-16!GO:0022613;ribonucleoprotein complex biogenesis and assembly;7.21768112904466e-16!GO:0006464;protein modification process;8.16093302486566e-16!GO:0019866;organelle inner membrane;8.6867739872123e-16!GO:0043687;post-translational protein modification;1.63531264083847e-15!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.69071935172098e-15!GO:0016462;pyrophosphatase activity;1.90146014598385e-15!GO:0016817;hydrolase activity, acting on acid anhydrides;2.28301147455038e-15!GO:0022618;protein-RNA complex assembly;2.32992835116005e-15!GO:0007242;intracellular signaling cascade;3.33841995158713e-15!GO:0017111;nucleoside-triphosphatase activity;5.33697410031915e-15!GO:0043285;biopolymer catabolic process;5.79095311657841e-15!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.37015590834479e-14!GO:0019941;modification-dependent protein catabolic process;1.60009278269325e-14!GO:0043632;modification-dependent macromolecule catabolic process;1.60009278269325e-14!GO:0032553;ribonucleotide binding;1.76482026804541e-14!GO:0032555;purine ribonucleotide binding;1.76482026804541e-14!GO:0000323;lytic vacuole;1.97506976289449e-14!GO:0005764;lysosome;1.97506976289449e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;2.16288875423785e-14!GO:0048519;negative regulation of biological process;2.17172317965233e-14!GO:0044257;cellular protein catabolic process;2.46294180476819e-14!GO:0006511;ubiquitin-dependent protein catabolic process;3.37221217328481e-14!GO:0006605;protein targeting;5.3653758985798e-14!GO:0017076;purine nucleotide binding;6.46487800891876e-14!GO:0012505;endomembrane system;6.54410071037541e-14!GO:0009057;macromolecule catabolic process;8.22026740219198e-14!GO:0006950;response to stress;1.10435599109696e-13!GO:0005743;mitochondrial inner membrane;2.69852792097517e-13!GO:0044248;cellular catabolic process;3.36166605980965e-13!GO:0005794;Golgi apparatus;3.51425003032378e-13!GO:0005768;endosome;4.16021148228735e-13!GO:0043069;negative regulation of programmed cell death;4.71908474741154e-13!GO:0000502;proteasome complex (sensu Eukaryota);4.88310683881135e-13!GO:0043066;negative regulation of apoptosis;5.14533229229539e-13!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;7.15541382169113e-13!GO:0016874;ligase activity;7.56475506570963e-13!GO:0016604;nuclear body;7.90312561690764e-13!GO:0009615;response to virus;9.54321308655185e-13!GO:0006793;phosphorus metabolic process;1.21846708911954e-12!GO:0006796;phosphate metabolic process;1.21846708911954e-12!GO:0006913;nucleocytoplasmic transport;1.7165695771444e-12!GO:0065009;regulation of a molecular function;2.04035801239182e-12!GO:0015934;large ribosomal subunit;2.14889163997316e-12!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.23616949359014e-12!GO:0044455;mitochondrial membrane part;2.37040690085601e-12!GO:0051246;regulation of protein metabolic process;2.46033470664949e-12!GO:0051169;nuclear transport;3.09390935724036e-12!GO:0008135;translation factor activity, nucleic acid binding;3.47688257633638e-12!GO:0030163;protein catabolic process;4.62004943706982e-12!GO:0003712;transcription cofactor activity;6.19020754273073e-12!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.04237300567137e-11!GO:0015935;small ribosomal subunit;2.09084527038014e-11!GO:0050794;regulation of cellular process;3.60785620438679e-11!GO:0016607;nuclear speck;3.65504813355336e-11!GO:0016310;phosphorylation;3.8055906635701e-11!GO:0006996;organelle organization and biogenesis;4.17641766678253e-11!GO:0003743;translation initiation factor activity;4.3578018583005e-11!GO:0006457;protein folding;4.52692594263599e-11!GO:0006413;translational initiation;8.55556597072459e-11!GO:0003676;nucleic acid binding;1.08962300733364e-10!GO:0016070;RNA metabolic process;1.09867150593811e-10!GO:0006916;anti-apoptosis;1.13926469994585e-10!GO:0006366;transcription from RNA polymerase II promoter;1.33235172494046e-10!GO:0005783;endoplasmic reticulum;1.74712615536179e-10!GO:0048522;positive regulation of cellular process;2.34065760163511e-10!GO:0051186;cofactor metabolic process;2.69710463792858e-10!GO:0009607;response to biotic stimulus;2.7146965536188e-10!GO:0005524;ATP binding;3.81451120957535e-10!GO:0006446;regulation of translational initiation;4.18128570286356e-10!GO:0005746;mitochondrial respiratory chain;4.61722205109494e-10!GO:0009967;positive regulation of signal transduction;5.5502356483276e-10!GO:0032559;adenyl ribonucleotide binding;5.97460062717532e-10!GO:0048518;positive regulation of biological process;8.47992535490808e-10!GO:0016787;hydrolase activity;8.79663099929704e-10!GO:0019787;small conjugating protein ligase activity;1.40449471062446e-09!GO:0043065;positive regulation of apoptosis;1.49100610113196e-09!GO:0004842;ubiquitin-protein ligase activity;1.97970730758165e-09!GO:0006417;regulation of translation;2.19033942820287e-09!GO:0043068;positive regulation of programmed cell death;2.19423263754724e-09!GO:0030554;adenyl nucleotide binding;2.28910970526115e-09!GO:0006732;coenzyme metabolic process;2.45784824198885e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.48065789258536e-09!GO:0008639;small protein conjugating enzyme activity;2.79728922417234e-09!GO:0050136;NADH dehydrogenase (quinone) activity;3.75370675300961e-09!GO:0003954;NADH dehydrogenase activity;3.75370675300961e-09!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.75370675300961e-09!GO:0031324;negative regulation of cellular metabolic process;3.92645592026796e-09!GO:0050790;regulation of catalytic activity;4.11219231362922e-09!GO:0005635;nuclear envelope;4.46648963335896e-09!GO:0050789;regulation of biological process;4.7739926757369e-09!GO:0005770;late endosome;4.90799610796746e-09!GO:0048193;Golgi vesicle transport;4.96108340111424e-09!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;4.99435577707703e-09!GO:0051082;unfolded protein binding;5.51026147224052e-09!GO:0015986;ATP synthesis coupled proton transport;6.68828427658342e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;6.68828427658342e-09!GO:0006259;DNA metabolic process;8.35434188783649e-09!GO:0017038;protein import;9.31795265633332e-09!GO:0019829;cation-transporting ATPase activity;9.31795265633332e-09!GO:0000398;nuclear mRNA splicing, via spliceosome;9.31795265633332e-09!GO:0000375;RNA splicing, via transesterification reactions;9.31795265633332e-09!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;9.31795265633332e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.04007472074333e-08!GO:0009056;catabolic process;1.09177356166418e-08!GO:0048468;cell development;1.19477690695088e-08!GO:0006917;induction of apoptosis;1.78136785386993e-08!GO:0051170;nuclear import;1.98663083527043e-08!GO:0012502;induction of programmed cell death;3.10368340833849e-08!GO:0065007;biological regulation;3.7230462180068e-08!GO:0044432;endoplasmic reticulum part;4.30181452806857e-08!GO:0009150;purine ribonucleotide metabolic process;4.34408633661693e-08!GO:0006606;protein import into nucleus;4.63770322548594e-08!GO:0009889;regulation of biosynthetic process;4.71786151746702e-08!GO:0044440;endosomal part;4.84245433317352e-08!GO:0010008;endosome membrane;4.84245433317352e-08!GO:0009259;ribonucleotide metabolic process;5.08852093138794e-08!GO:0009152;purine ribonucleotide biosynthetic process;5.17814869017777e-08!GO:0009892;negative regulation of metabolic process;6.46396905377108e-08!GO:0005774;vacuolar membrane;6.93906748936226e-08!GO:0006754;ATP biosynthetic process;7.07018502799899e-08!GO:0006753;nucleoside phosphate metabolic process;7.07018502799899e-08!GO:0006163;purine nucleotide metabolic process;7.47978653421044e-08!GO:0031326;regulation of cellular biosynthetic process;7.64053918482565e-08!GO:0042775;organelle ATP synthesis coupled electron transport;7.67893193531514e-08!GO:0042773;ATP synthesis coupled electron transport;7.67893193531514e-08!GO:0016881;acid-amino acid ligase activity;8.67214141763179e-08!GO:0030964;NADH dehydrogenase complex (quinone);9.09164265498533e-08!GO:0045271;respiratory chain complex I;9.09164265498533e-08!GO:0005747;mitochondrial respiratory chain complex I;9.09164265498533e-08!GO:0006164;purine nucleotide biosynthetic process;1.00536872850969e-07!GO:0005730;nucleolus;1.03833421285756e-07!GO:0009055;electron carrier activity;1.08494453781061e-07!GO:0003924;GTPase activity;1.3955531989357e-07!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.55493134495185e-07!GO:0009260;ribonucleotide biosynthetic process;1.65327032731287e-07!GO:0016887;ATPase activity;1.68041777264032e-07!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;1.69457452276346e-07!GO:0016564;transcription repressor activity;2.00900453080193e-07!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.00900453080193e-07!GO:0006954;inflammatory response;2.03900508334337e-07!GO:0003713;transcription coactivator activity;2.2327817629251e-07!GO:0009966;regulation of signal transduction;2.31054168783472e-07!GO:0005525;GTP binding;2.3281758554271e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.43632536603e-07!GO:0005793;ER-Golgi intermediate compartment;2.46842209918851e-07!GO:0042623;ATPase activity, coupled;2.53752205990073e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.67588954949318e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.67588954949318e-07!GO:0046034;ATP metabolic process;2.93124123434591e-07!GO:0044437;vacuolar part;3.41867401929541e-07!GO:0000074;regulation of progression through cell cycle;3.42690249694029e-07!GO:0051726;regulation of cell cycle;3.42690249694029e-07!GO:0016469;proton-transporting two-sector ATPase complex;3.64487918167621e-07!GO:0009142;nucleoside triphosphate biosynthetic process;3.92076696995279e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;3.92076696995279e-07!GO:0005765;lysosomal membrane;4.42045806238894e-07!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.48978686481248e-07!GO:0044453;nuclear membrane part;5.51993484036713e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;5.71383336471909e-07!GO:0009144;purine nucleoside triphosphate metabolic process;5.71383336471909e-07!GO:0019899;enzyme binding;5.82069983473946e-07!GO:0051188;cofactor biosynthetic process;5.86872981929393e-07!GO:0007264;small GTPase mediated signal transduction;5.96298321475442e-07!GO:0042175;nuclear envelope-endoplasmic reticulum network;6.66862728080416e-07!GO:0031965;nuclear membrane;6.75488761326272e-07!GO:0008565;protein transporter activity;6.89969254945755e-07!GO:0005789;endoplasmic reticulum membrane;7.00315842271776e-07!GO:0009199;ribonucleoside triphosphate metabolic process;7.72831471052645e-07!GO:0005839;proteasome core complex (sensu Eukaryota);1.11938483752386e-06!GO:0009108;coenzyme biosynthetic process;1.14031887371344e-06!GO:0016044;membrane organization and biogenesis;1.14031887371344e-06!GO:0008047;enzyme activator activity;1.36804945803059e-06!GO:0007049;cell cycle;1.42590020328085e-06!GO:0016481;negative regulation of transcription;1.83415037651551e-06!GO:0006952;defense response;1.91351447783567e-06!GO:0009141;nucleoside triphosphate metabolic process;1.93983924031576e-06!GO:0045786;negative regulation of progression through cell cycle;2.08408984485164e-06!GO:0032446;protein modification by small protein conjugation;2.38909218722462e-06!GO:0006752;group transfer coenzyme metabolic process;2.52468571430498e-06!GO:0031980;mitochondrial lumen;2.59503521574222e-06!GO:0005759;mitochondrial matrix;2.59503521574222e-06!GO:0006461;protein complex assembly;3.00826523646472e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;3.01256742689304e-06!GO:0016567;protein ubiquitination;3.53353548840909e-06!GO:0032561;guanyl ribonucleotide binding;4.24848814079461e-06!GO:0019001;guanyl nucleotide binding;4.24848814079461e-06!GO:0051707;response to other organism;5.76904066708987e-06!GO:0004298;threonine endopeptidase activity;6.03137483319793e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;6.32058322608411e-06!GO:0016563;transcription activator activity;9.70458964516797e-06!GO:0031252;leading edge;9.97558615542261e-06!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.00107502823697e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;1.03121739255595e-05!GO:0015399;primary active transmembrane transporter activity;1.03121739255595e-05!GO:0004386;helicase activity;1.21697331085495e-05!GO:0030099;myeloid cell differentiation;1.31315039714016e-05!GO:0031982;vesicle;1.34369103495009e-05!GO:0050657;nucleic acid transport;1.34899363118243e-05!GO:0051236;establishment of RNA localization;1.34899363118243e-05!GO:0050658;RNA transport;1.34899363118243e-05!GO:0043228;non-membrane-bound organelle;1.34899363118243e-05!GO:0043232;intracellular non-membrane-bound organelle;1.34899363118243e-05!GO:0031902;late endosome membrane;1.55868677133714e-05!GO:0005643;nuclear pore;1.63649321664439e-05!GO:0006325;establishment and/or maintenance of chromatin architecture;1.63649321664439e-05!GO:0006403;RNA localization;1.74458710752511e-05!GO:0008026;ATP-dependent helicase activity;1.78709948346352e-05!GO:0006888;ER to Golgi vesicle-mediated transport;2.07740842301118e-05!GO:0048475;coated membrane;2.26508320641106e-05!GO:0030117;membrane coat;2.26508320641106e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;2.2695222770715e-05!GO:0030097;hemopoiesis;2.30892760520112e-05!GO:0016197;endosome transport;2.30903017971412e-05!GO:0006897;endocytosis;2.4672205308772e-05!GO:0010324;membrane invagination;2.4672205308772e-05!GO:0016568;chromatin modification;2.48012442699713e-05!GO:0045321;leukocyte activation;2.66843159214637e-05!GO:0003714;transcription corepressor activity;2.91512930911566e-05!GO:0005769;early endosome;3.4323509841466e-05!GO:0019222;regulation of metabolic process;3.54058144545658e-05!GO:0006323;DNA packaging;3.64880589336069e-05!GO:0030120;vesicle coat;4.05579778609329e-05!GO:0030662;coated vesicle membrane;4.05579778609329e-05!GO:0051789;response to protein stimulus;4.15652038189819e-05!GO:0006986;response to unfolded protein;4.15652038189819e-05!GO:0009611;response to wounding;4.6273999566282e-05!GO:0006401;RNA catabolic process;5.94269810623103e-05!GO:0009060;aerobic respiration;6.17648252529606e-05!GO:0051336;regulation of hydrolase activity;6.25113637930844e-05!GO:0001816;cytokine production;6.58097241624746e-05!GO:0045259;proton-transporting ATP synthase complex;7.43506332153555e-05!GO:0006974;response to DNA damage stimulus;7.59945263962885e-05!GO:0031410;cytoplasmic vesicle;7.66382531745073e-05!GO:0044431;Golgi apparatus part;7.76431610146547e-05!GO:0008632;apoptotic program;8.35559068593463e-05!GO:0043492;ATPase activity, coupled to movement of substances;9.18313928828584e-05!GO:0003697;single-stranded DNA binding;9.18313928828584e-05!GO:0051338;regulation of transferase activity;9.93954390200012e-05!GO:0006613;cotranslational protein targeting to membrane;0.000105560203941036!GO:0046930;pore complex;0.000109090848698308!GO:0003724;RNA helicase activity;0.000112684410349462!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000114992003130759!GO:0043566;structure-specific DNA binding;0.000127583440985106!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.000143343568561104!GO:0051028;mRNA transport;0.000144576091971092!GO:0046822;regulation of nucleocytoplasmic transport;0.000153807058188451!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000169685236416575!GO:0031988;membrane-bound vesicle;0.000171175870294084!GO:0043549;regulation of kinase activity;0.000198589414332312!GO:0030695;GTPase regulator activity;0.000209110962048532!GO:0000151;ubiquitin ligase complex;0.000218353698576884!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.00021949688846174!GO:0005096;GTPase activator activity;0.000231209496996729!GO:0045333;cellular respiration;0.000247769349307431!GO:0006818;hydrogen transport;0.000252486917108944!GO:0000245;spliceosome assembly;0.000257408329090763!GO:0045859;regulation of protein kinase activity;0.000258024979737041!GO:0005885;Arp2/3 protein complex;0.000259954320156581!GO:0032940;secretion by cell;0.000270464022493853!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.00027700829395951!GO:0005798;Golgi-associated vesicle;0.000285011239394249!GO:0008234;cysteine-type peptidase activity;0.000287546024393882!GO:0002520;immune system development;0.000304354834494769!GO:0004674;protein serine/threonine kinase activity;0.000304784363729548!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000314740272987139!GO:0008654;phospholipid biosynthetic process;0.000317301071830946!GO:0009893;positive regulation of metabolic process;0.000327734482323755!GO:0015992;proton transport;0.000335869576641977!GO:0051223;regulation of protein transport;0.000347334432384587!GO:0002521;leukocyte differentiation;0.000348455258388129!GO:0051427;hormone receptor binding;0.000392251598123873!GO:0007259;JAK-STAT cascade;0.000402038477672599!GO:0046519;sphingoid metabolic process;0.000403064607232338!GO:0048534;hemopoietic or lymphoid organ development;0.000414250899124894!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000418513512860665!GO:0022890;inorganic cation transmembrane transporter activity;0.000431551452253599!GO:0051168;nuclear export;0.00043675981318505!GO:0022402;cell cycle process;0.000466557152229249!GO:0065002;intracellular protein transport across a membrane;0.000470297052197924!GO:0005057;receptor signaling protein activity;0.000477604773260879!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000481540117993335!GO:0045637;regulation of myeloid cell differentiation;0.000487654583209005!GO:0016023;cytoplasmic membrane-bound vesicle;0.000490435309407187!GO:0030532;small nuclear ribonucleoprotein complex;0.000491217577591061!GO:0007005;mitochondrion organization and biogenesis;0.000491217577591061!GO:0007034;vacuolar transport;0.000491217577591061!GO:0002474;antigen processing and presentation of peptide antigen via MHC class I;0.000491964907288907!GO:0001775;cell activation;0.000515476201635497!GO:0007040;lysosome organization and biogenesis;0.000520183683927163!GO:0016740;transferase activity;0.000542200796646739!GO:0051276;chromosome organization and biogenesis;0.000545779982793142!GO:0046649;lymphocyte activation;0.000579791502173619!GO:0007050;cell cycle arrest;0.000601782664936206!GO:0006402;mRNA catabolic process;0.000614718623117386!GO:0035257;nuclear hormone receptor binding;0.000614718623117386!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000652689250528313!GO:0001726;ruffle;0.000678969959963484!GO:0006672;ceramide metabolic process;0.000704736069374158!GO:0042110;T cell activation;0.000715049141897489!GO:0006612;protein targeting to membrane;0.00071689524462411!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000720488048769207!GO:0007041;lysosomal transport;0.00072779635913574!GO:0006643;membrane lipid metabolic process;0.000804400600732653!GO:0006281;DNA repair;0.000810123250369689!GO:0051090;regulation of transcription factor activity;0.000846794311572167!GO:0046983;protein dimerization activity;0.000885021543351391!GO:0005083;small GTPase regulator activity;0.000920428793528583!GO:0043085;positive regulation of catalytic activity;0.000931049229440808!GO:0005761;mitochondrial ribosome;0.00100385669578202!GO:0000313;organellar ribosome;0.00100385669578202!GO:0005667;transcription factor complex;0.00101350167457634!GO:0033157;regulation of intracellular protein transport;0.00106915396541395!GO:0042306;regulation of protein import into nucleus;0.00106915396541395!GO:0005741;mitochondrial outer membrane;0.0010755388633378!GO:0007033;vacuole organization and biogenesis;0.00118588161705699!GO:0009117;nucleotide metabolic process;0.00124671459841084!GO:0030036;actin cytoskeleton organization and biogenesis;0.00125029640498561!GO:0002274;myeloid leukocyte activation;0.0012764604827866!GO:0019221;cytokine and chemokine mediated signaling pathway;0.00129259343116097!GO:0031323;regulation of cellular metabolic process;0.0014805830634131!GO:0007265;Ras protein signal transduction;0.0014805830634131!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.00148494387498559!GO:0030149;sphingolipid catabolic process;0.00149690175473283!GO:0000139;Golgi membrane;0.00153412129784562!GO:0003729;mRNA binding;0.0015464013228848!GO:0033116;ER-Golgi intermediate compartment membrane;0.00158387306501543!GO:0002757;immune response-activating signal transduction;0.00158444417946772!GO:0002252;immune effector process;0.00160161645805351!GO:0008186;RNA-dependent ATPase activity;0.00161137796287069!GO:0065004;protein-DNA complex assembly;0.00170804426772105!GO:0045893;positive regulation of transcription, DNA-dependent;0.0017267254320156!GO:0045941;positive regulation of transcription;0.00173338456159901!GO:0005637;nuclear inner membrane;0.00185228804915724!GO:0006099;tricarboxylic acid cycle;0.00192267342997006!GO:0046356;acetyl-CoA catabolic process;0.00192267342997006!GO:0045892;negative regulation of transcription, DNA-dependent;0.00192987134978037!GO:0006091;generation of precursor metabolites and energy;0.00192987134978037!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.00207692476471191!GO:0022415;viral reproductive process;0.00223022811325359!GO:0060090;molecular adaptor activity;0.00229523722314508!GO:0042254;ribosome biogenesis and assembly;0.00232672180737051!GO:0031325;positive regulation of cellular metabolic process;0.00234340174235504!GO:0042221;response to chemical stimulus;0.0026042955865246!GO:0044262;cellular carbohydrate metabolic process;0.00267934556410548!GO:0006919;caspase activation;0.00270403261935197!GO:0043281;regulation of caspase activity;0.00271333770540422!GO:0016301;kinase activity;0.00290096699208482!GO:0042990;regulation of transcription factor import into nucleus;0.00300128142769729!GO:0042991;transcription factor import into nucleus;0.00300128142769729!GO:0045045;secretory pathway;0.00305780883770352!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00318265720547104!GO:0043280;positive regulation of caspase activity;0.00336224482127353!GO:0051187;cofactor catabolic process;0.00337937253387639!GO:0002764;immune response-regulating signal transduction;0.00345121579626724!GO:0045454;cell redox homeostasis;0.00350788308736348!GO:0008383;manganese superoxide dismutase activity;0.00362402865281122!GO:0001315;age-dependent response to reactive oxygen species;0.00362402865281122!GO:0031901;early endosome membrane;0.00364972423944893!GO:0031072;heat shock protein binding;0.0038121569617593!GO:0006468;protein amino acid phosphorylation;0.00384286869756837!GO:0009719;response to endogenous stimulus;0.00403923143309655!GO:0018193;peptidyl-amino acid modification;0.00406352635118039!GO:0031968;organelle outer membrane;0.00407739560387437!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00423885707123464!GO:0004004;ATP-dependent RNA helicase activity;0.00423885707123464!GO:0016251;general RNA polymerase II transcription factor activity;0.00430426165484194!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.00441369251245127!GO:0004812;aminoacyl-tRNA ligase activity;0.00441369251245127!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.00441369251245127!GO:0019867;outer membrane;0.00452234542816329!GO:0006352;transcription initiation;0.00476474405937477!GO:0006891;intra-Golgi vesicle-mediated transport;0.00484927337429768!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00489560740047833!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.00489779708807929!GO:0006084;acetyl-CoA metabolic process;0.00504258436911047!GO:0003725;double-stranded RNA binding;0.00519475923754632!GO:0048487;beta-tubulin binding;0.00525081217634697!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00533949245942305!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00533949245942305!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00533949245942305!GO:0030218;erythrocyte differentiation;0.0057270769622737!GO:0002250;adaptive immune response;0.00590918356119926!GO:0002460;adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains;0.00590918356119926!GO:0004185;serine carboxypeptidase activity;0.00591800675013944!GO:0043087;regulation of GTPase activity;0.00597700480209235!GO:0005099;Ras GTPase activator activity;0.00601009605421254!GO:0009109;coenzyme catabolic process;0.00601009605421254!GO:0043038;amino acid activation;0.00601009605421254!GO:0006418;tRNA aminoacylation for protein translation;0.00601009605421254!GO:0043039;tRNA aminoacylation;0.00601009605421254!GO:0006399;tRNA metabolic process;0.00632851342481871!GO:0051092;activation of NF-kappaB transcription factor;0.00632851342481871!GO:0006935;chemotaxis;0.00638676671378028!GO:0042330;taxis;0.00638676671378028!GO:0006607;NLS-bearing substrate import into nucleus;0.00647816327146831!GO:0043021;ribonucleoprotein binding;0.00692888495374686!GO:0046966;thyroid hormone receptor binding;0.00702156685100924!GO:0019882;antigen processing and presentation;0.00726788964113861!GO:0019377;glycolipid catabolic process;0.00726788964113861!GO:0030867;rough endoplasmic reticulum membrane;0.00732617779097651!GO:0043623;cellular protein complex assembly;0.00732617779097651!GO:0002429;immune response-activating cell surface receptor signaling pathway;0.00746127234994746!GO:0030041;actin filament polymerization;0.00749009055178141!GO:0009165;nucleotide biosynthetic process;0.00765612610228642!GO:0046467;membrane lipid biosynthetic process;0.00774542075948706!GO:0006458;'de novo' protein folding;0.00779034097360994!GO:0051084;'de novo' posttranslational protein folding;0.00779034097360994!GO:0002504;antigen processing and presentation of peptide or polysaccharide antigen via MHC class II;0.00836046247503294!GO:0030029;actin filament-based process;0.00856950457009668!GO:0051345;positive regulation of hydrolase activity;0.00856950457009668!GO:0032386;regulation of intracellular transport;0.00879952137501386!GO:0001817;regulation of cytokine production;0.00904206160314579!GO:0019883;antigen processing and presentation of endogenous antigen;0.00919381903058951!GO:0004197;cysteine-type endopeptidase activity;0.00945338316808426!GO:0031625;ubiquitin protein ligase binding;0.00964190541110737!GO:0010468;regulation of gene expression;0.00966404913120519!GO:0033673;negative regulation of kinase activity;0.00969301854843045!GO:0006469;negative regulation of protein kinase activity;0.00969301854843045!GO:0005484;SNAP receptor activity;0.00992496986372395!GO:0016779;nucleotidyltransferase activity;0.00992496986372395!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00992581472225925!GO:0046466;membrane lipid catabolic process;0.0102606286448295!GO:0030658;transport vesicle membrane;0.0104585460203915!GO:0000209;protein polyubiquitination;0.0105307723670457!GO:0051059;NF-kappaB binding;0.0106007554545134!GO:0030176;integral to endoplasmic reticulum membrane;0.0108083290189112!GO:0048002;antigen processing and presentation of peptide antigen;0.0109129844329365!GO:0002682;regulation of immune system process;0.010950752652088!GO:0002237;response to molecule of bacterial origin;0.0109749480765821!GO:0030127;COPII vesicle coat;0.0109917997810295!GO:0012507;ER to Golgi transport vesicle membrane;0.0109917997810295!GO:0043433;negative regulation of transcription factor activity;0.0112450935124009!GO:0016791;phosphoric monoester hydrolase activity;0.0113013971154148!GO:0005062;hematopoietin/interferon-class (D200-domain) cytokine receptor signal transducer activity;0.0113237340825069!GO:0030134;ER to Golgi transport vesicle;0.0116554478160241!GO:0030521;androgen receptor signaling pathway;0.0118854598141739!GO:0006665;sphingolipid metabolic process;0.0119650557819066!GO:0030217;T cell differentiation;0.0120067981142582!GO:0002684;positive regulation of immune system process;0.0121856730791757!GO:0002467;germinal center formation;0.0124056081117273!GO:0051348;negative regulation of transferase activity;0.0125230143083126!GO:0045639;positive regulation of myeloid cell differentiation;0.01285207176378!GO:0030518;steroid hormone receptor signaling pathway;0.0130278788916487!GO:0005070;SH3/SH2 adaptor activity;0.0130884148093925!GO:0008637;apoptotic mitochondrial changes;0.0132383125188593!GO:0030027;lamellipodium;0.013728306645552!GO:0006749;glutathione metabolic process;0.0137307949874166!GO:0032763;regulation of mast cell cytokine production;0.0137307949874166!GO:0032762;mast cell cytokine production;0.0137307949874166!GO:0048500;signal recognition particle;0.0138001707857496!GO:0019079;viral genome replication;0.0139157567814877!GO:0002440;production of molecular mediator of immune response;0.0142865837251923!GO:0002768;immune response-regulating cell surface receptor signaling pathway;0.0144131219155566!GO:0033367;protein localization in mast cell secretory granule;0.0144961146112449!GO:0033365;protein localization in organelle;0.0144961146112449!GO:0033371;T cell secretory granule organization and biogenesis;0.0144961146112449!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.0144961146112449!GO:0033375;protease localization in T cell secretory granule;0.0144961146112449!GO:0042629;mast cell granule;0.0144961146112449!GO:0033377;maintenance of protein localization in T cell secretory granule;0.0144961146112449!GO:0033364;mast cell secretory granule organization and biogenesis;0.0144961146112449!GO:0033380;granzyme B localization in T cell secretory granule;0.0144961146112449!GO:0033379;maintenance of protease localization in T cell secretory granule;0.0144961146112449!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.0144961146112449!GO:0033368;protease localization in mast cell secretory granule;0.0144961146112449!GO:0033366;protein localization in secretory granule;0.0144961146112449!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.0144961146112449!GO:0033374;protein localization in T cell secretory granule;0.0144961146112449!GO:0042613;MHC class II protein complex;0.0150045468135506!GO:0016363;nuclear matrix;0.0157518532177637!GO:0050778;positive regulation of immune response;0.0167009521218574!GO:0042802;identical protein binding;0.0167157865372472!GO:0001819;positive regulation of cytokine production;0.0168898613899543!GO:0015631;tubulin binding;0.0170329118836239!GO:0006611;protein export from nucleus;0.01711969713286!GO:0045646;regulation of erythrocyte differentiation;0.0174152980405541!GO:0005813;centrosome;0.0175320835340238!GO:0003702;RNA polymerase II transcription factor activity;0.0175690218297036!GO:0008139;nuclear localization sequence binding;0.0176121260465416!GO:0043621;protein self-association;0.0176300633743552!GO:0019904;protein domain specific binding;0.017671274627!GO:0002443;leukocyte mediated immunity;0.0181731646588031!GO:0019210;kinase inhibitor activity;0.0186337448113232!GO:0046479;glycosphingolipid catabolic process;0.018717943428077!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0187678474939823!GO:0045047;protein targeting to ER;0.0187678474939823!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0187773150848197!GO:0051091;positive regulation of transcription factor activity;0.018832609495203!GO:0051252;regulation of RNA metabolic process;0.0188693014764558!GO:0006414;translational elongation;0.0193268343838219!GO:0004860;protein kinase inhibitor activity;0.0197650689658217!GO:0019220;regulation of phosphate metabolic process;0.0201724329673129!GO:0051174;regulation of phosphorus metabolic process;0.0201724329673129!GO:0006354;RNA elongation;0.0201724329673129!GO:0005048;signal sequence binding;0.0203285841775214!GO:0016491;oxidoreductase activity;0.0204420099617505!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0205144965231336!GO:0030098;lymphocyte differentiation;0.0208443513691545!GO:0002822;regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains.;0.0209904470704186!GO:0002819;regulation of adaptive immune response;0.0209904470704186!GO:0043022;ribosome binding;0.021137288936716!GO:0046979;TAP2 binding;0.021137288936716!GO:0046977;TAP binding;0.021137288936716!GO:0046978;TAP1 binding;0.021137288936716!GO:0051247;positive regulation of protein metabolic process;0.0214063092707322!GO:0030224;monocyte differentiation;0.0217615837011649!GO:0002224;toll-like receptor signaling pathway;0.0218538324811546!GO:0002221;pattern recognition receptor signaling pathway;0.0218538324811546!GO:0050811;GABA receptor binding;0.0224793163846391!GO:0030693;caspase activity;0.0224793163846391!GO:0030660;Golgi-associated vesicle membrane;0.0225231417105984!GO:0051098;regulation of binding;0.02262976150148!GO:0017091;AU-rich element binding;0.0226344224337535!GO:0050779;RNA destabilization;0.0226344224337535!GO:0000289;poly(A) tail shortening;0.0226344224337535!GO:0051085;chaperone cofactor-dependent protein folding;0.0226772509656061!GO:0003727;single-stranded RNA binding;0.0230078118637007!GO:0008624;induction of apoptosis by extracellular signals;0.0230078118637007!GO:0006644;phospholipid metabolic process;0.0230078118637007!GO:0050776;regulation of immune response;0.0231236906077662!GO:0030663;COPI coated vesicle membrane;0.0236153478532315!GO:0030126;COPI vesicle coat;0.0236153478532315!GO:0050900;leukocyte migration;0.0236311043241408!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0237081616383908!GO:0048146;positive regulation of fibroblast proliferation;0.0238257475955691!GO:0008629;induction of apoptosis by intracellular signals;0.023879876829475!GO:0019843;rRNA binding;0.0240033977068417!GO:0000785;chromatin;0.0241363540651314!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0241552120976094!GO:0006650;glycerophospholipid metabolic process;0.0242013933327421!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0250589493905543!GO:0030137;COPI-coated vesicle;0.0254539769524454!GO:0030118;clathrin coat;0.0254539769524454!GO:0030133;transport vesicle;0.0255587405594852!GO:0003690;double-stranded DNA binding;0.0256479645432985!GO:0051052;regulation of DNA metabolic process;0.026164766754354!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0263338242348323!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0263338242348323!GO:0006333;chromatin assembly or disassembly;0.0264123475285046!GO:0042108;positive regulation of cytokine biosynthetic process;0.0265918881789833!GO:0030503;regulation of cell redox homeostasis;0.0277672737529352!GO:0048144;fibroblast proliferation;0.0283826869491566!GO:0048145;regulation of fibroblast proliferation;0.0283826869491566!GO:0000049;tRNA binding;0.0285933379699767!GO:0031327;negative regulation of cellular biosynthetic process;0.0295515665616427!GO:0002253;activation of immune response;0.0295767891955061!GO:0030433;ER-associated protein catabolic process;0.0295882799694028!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0295882799694028!GO:0050851;antigen receptor-mediated signaling pathway;0.0298633712830812!GO:0042611;MHC protein complex;0.0301773245020162!GO:0032318;regulation of Ras GTPase activity;0.0303068073058613!GO:0002573;myeloid leukocyte differentiation;0.0310955678015907!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0313366639236344!GO:0007162;negative regulation of cell adhesion;0.031355848159651!GO:0006364;rRNA processing;0.0314698859625292!GO:0016072;rRNA metabolic process;0.0317552304956142!GO:0004177;aminopeptidase activity;0.0318394574802552!GO:0000165;MAPKKK cascade;0.031993043512481!GO:0045792;negative regulation of cell size;0.0329780980414331!GO:0051023;regulation of immunoglobulin secretion;0.0330728854855552!GO:0045994;positive regulation of translational initiation by iron;0.0330728854855552!GO:0032760;positive regulation of tumor necrosis factor production;0.0331734011193951!GO:0019318;hexose metabolic process;0.0331734011193951!GO:0005815;microtubule organizing center;0.0333064249243871!GO:0000118;histone deacetylase complex;0.0334740930700627!GO:0043300;regulation of leukocyte degranulation;0.0337225713297307!GO:0005869;dynactin complex;0.0344832684712797!GO:0001562;response to protozoan;0.0348371811925865!GO:0000339;RNA cap binding;0.0348858846613022!GO:0045113;regulation of integrin biosynthetic process;0.0350322769771751!GO:0045112;integrin biosynthetic process;0.0350322769771751!GO:0017166;vinculin binding;0.0351110294788342!GO:0043488;regulation of mRNA stability;0.0351752033413055!GO:0043487;regulation of RNA stability;0.0351752033413055!GO:0042348;NF-kappaB import into nucleus;0.0351828776828236!GO:0042345;regulation of NF-kappaB import into nucleus;0.0351828776828236!GO:0005684;U2-dependent spliceosome;0.035328276295495!GO:0002444;myeloid leukocyte mediated immunity;0.0355502313808704!GO:0015980;energy derivation by oxidation of organic compounds;0.0358987085650965!GO:0008312;7S RNA binding;0.0362667465165461!GO:0000082;G1/S transition of mitotic cell cycle;0.0364880256222904!GO:0044255;cellular lipid metabolic process;0.0366072430235375!GO:0051101;regulation of DNA binding;0.0366539680239705!GO:0015923;mannosidase activity;0.0369369850868266!GO:0045089;positive regulation of innate immune response;0.0369951394606308!GO:0045088;regulation of innate immune response;0.0369951394606308!GO:0008333;endosome to lysosome transport;0.0373665337548199!GO:0033033;negative regulation of myeloid cell apoptosis;0.0373665337548199!GO:0001803;regulation of type III hypersensitivity;0.0373665337548199!GO:0032733;positive regulation of interleukin-10 production;0.0373665337548199!GO:0033025;regulation of mast cell apoptosis;0.0373665337548199!GO:0001805;positive regulation of type III hypersensitivity;0.0373665337548199!GO:0033023;mast cell homeostasis;0.0373665337548199!GO:0002431;Fc receptor mediated stimulatory signaling pathway;0.0373665337548199!GO:0033032;regulation of myeloid cell apoptosis;0.0373665337548199!GO:0001802;type III hypersensitivity;0.0373665337548199!GO:0033028;myeloid cell apoptosis;0.0373665337548199!GO:0042590;antigen processing and presentation of exogenous peptide antigen via MHC class I;0.0373665337548199!GO:0033026;negative regulation of mast cell apoptosis;0.0373665337548199!GO:0033024;mast cell apoptosis;0.0373665337548199!GO:0015036;disulfide oxidoreductase activity;0.0374740423853397!GO:0003746;translation elongation factor activity;0.0375456296916977!GO:0006350;transcription;0.0386421693328987!GO:0008286;insulin receptor signaling pathway;0.0387157501265648!GO:0043407;negative regulation of MAP kinase activity;0.0388872205540277!GO:0002697;regulation of immune effector process;0.0389127530326497!GO:0005905;coated pit;0.0389127530326497!GO:0008361;regulation of cell size;0.0390493745884404!GO:0005669;transcription factor TFIID complex;0.0390493745884404!GO:0019752;carboxylic acid metabolic process;0.0391535951520736!GO:0045936;negative regulation of phosphate metabolic process;0.0391906214673438!GO:0030308;negative regulation of cell growth;0.0393164120425912!GO:0000287;magnesium ion binding;0.0396034648343762!GO:0046426;negative regulation of JAK-STAT cascade;0.0397181187871026!GO:0005791;rough endoplasmic reticulum;0.0399210453103437!GO:0035035;histone acetyltransferase binding;0.04013952297004!GO:0016311;dephosphorylation;0.0403788910125003!GO:0033549;MAP kinase phosphatase activity;0.040744226199615!GO:0017017;MAP kinase tyrosine/serine/threonine phosphatase activity;0.040744226199615!GO:0009890;negative regulation of biosynthetic process;0.0412523759560304!GO:0006984;ER-nuclear signaling pathway;0.0413567635687452!GO:0051051;negative regulation of transport;0.0417892054095075!GO:0030384;phosphoinositide metabolic process;0.0417892054095075!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0423690566303416!GO:0006509;membrane protein ectodomain proteolysis;0.0429603231619203!GO:0033619;membrane protein proteolysis;0.0429603231619203!GO:0008538;proteasome activator activity;0.0430116012888852!GO:0006740;NADPH regeneration;0.0435284956660726!GO:0006098;pentose-phosphate shunt;0.0435284956660726!GO:0016408;C-acyltransferase activity;0.0437729845511464!GO:0019058;viral infectious cycle;0.0438378168289748!GO:0006465;signal peptide processing;0.0441429085962867!GO:0006914;autophagy;0.0442457204015457!GO:0019955;cytokine binding;0.0447377288024666!GO:0030522;intracellular receptor-mediated signaling pathway;0.0449633514245034!GO:0006082;organic acid metabolic process;0.0449633514245034!GO:0006007;glucose catabolic process;0.0451828396719992!GO:0051235;maintenance of localization;0.0451828396719992!GO:0042992;negative regulation of transcription factor import into nucleus;0.0456395430746476!GO:0042308;negative regulation of protein import into nucleus;0.0456395430746476!GO:0005152;interleukin-1 receptor antagonist activity;0.0474092101169741!GO:0030353;fibroblast growth factor receptor antagonist activity;0.0474092101169741!GO:0042116;macrophage activation;0.0482411223632924!GO:0006979;response to oxidative stress;0.0483959652726926!GO:0051920;peroxiredoxin activity;0.0484429184618153!GO:0004722;protein serine/threonine phosphatase activity;0.0488002850295994!GO:0045746;negative regulation of Notch signaling pathway;0.0493017131185275!GO:0000096;sulfur amino acid metabolic process;0.0494420156084315!GO:0002718;regulation of cytokine production during immune response;0.0498553508167136!GO:0002367;cytokine production during immune response;0.0498553508167136!GO:0002700;regulation of production of molecular mediator of immune response;0.0498553508167136!GO:0045576;mast cell activation;0.0498553508167136!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.0499221703420285 | |||
|sample_id=11860 | |||
|sample_note= | |||
|sample_sex=female | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue= | |||
|top_motifs=STAT5{A,B}:6.04730313201;STAT2,4,6:5.91780238851;FOSL2:4.7890680776;IRF7:4.75527392776;NFE2:4.74366025827;IRF1,2:4.72039007102;NFE2L2:4.59235091947;CEBPA,B_DDIT3:4.52556143357;FOS_FOS{B,L1}_JUN{B,D}:4.43574560952;BACH2:4.3581695063;HLF:4.32448295046;STAT1,3:4.19795499726;PAX2:3.58341693728;SPIB:3.43420274536;NANOG{mouse}:3.38750142984;NFIL3:3.05380925925;SPI1:3.03730311516;NR1H4:3.03108700897;NFKB1_REL_RELA:3.01073485757;SREBF1,2:2.95726593749;FOXP3:2.70455308098;ETS1,2:2.70358324222;ATF6:2.57804600478;ATF4:2.49474979493;ATF5_CREB3:2.49392021711;EP300:2.4615099249;DMAP1_NCOR{1,2}_SMARC:2.38201462932;FOXN1:2.20233157028;HSF1,2:2.15137127393;NFATC1..3:2.02883153083;NFE2L1:2.00854970535;CDX1,2,4:1.91412863075;RUNX1..3:1.87297209835;CREB1:1.82150118596;ALX4:1.75597098733;JUN:1.67005361974;PAX8:1.57818627505;HMGA1,2:1.51033363206;HIF1A:1.44771196577;XBP1:1.3754440942;RXRA_VDR{dimer}:1.37472831069;ELF1,2,4:1.31376153;PDX1:1.23209510797;ATF2:1.21739433649;TGIF1:1.20439126681;PITX1..3:1.15221139705;MAFB:1.09328793378;NR6A1:1.01723120209;ZBTB16:0.954377572836;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.867743247176;PPARG:0.76909738834;SRF:0.693132564624;IKZF1:0.644686364494;HOX{A5,B5}:0.637853214822;PAX3,7:0.60900319048;HMX1:0.554221847514;PRDM1:0.522830173785;PAX4:0.520669075985;TFCP2:0.403218036521;BPTF:0.348930428571;HBP1_HMGB_SSRP1_UBTF:0.224381386889;IKZF2:0.210574182803;GLI1..3:0.189472979779;FOXD3:0.183843905314;FOXO1,3,4:0.181337087507;EN1,2:0.128147966547;TLX2:0.116594917415;GATA4:0.0768607304719;ESRRA:0.0610812296695;SPZ1:-0.0688058073145;PAX1,9:-0.103063845346;TBP:-0.120481523577;FOXL1:-0.138282487934;DBP:-0.184602613228;MEF2{A,B,C,D}:-0.222697398661;AHR_ARNT_ARNT2:-0.246925844108;SMAD1..7,9:-0.258604784941;EGR1..3:-0.290653316842;MYB:-0.30860346431;ALX1:-0.319159570038;FOXM1:-0.324962951369;POU2F1..3:-0.395731631997;RXR{A,B,G}:-0.477730796166;NKX6-1,2:-0.496397818806;FOX{D1,D2}:-0.51369556726;NKX3-2:-0.519029591195;ESR1:-0.544964005404;VSX1,2:-0.553621765388;RBPJ:-0.564937529778;NKX3-1:-0.603825594256;OCT4_SOX2{dimer}:-0.637734464915;FOXP1:-0.645381325886;NR3C1:-0.680669789957;RFX2..5_RFXANK_RFXAP:-0.704248441492;NANOG:-0.733271871826;MZF1:-0.811506871536;TFAP4:-0.813454225681;HOX{A6,A7,B6,B7}:-0.873706848747;NKX2-2,8:-0.916295702463;POU6F1:-0.93644905736;ZNF238:-0.978398975586;REST:-0.983508015352;HOXA9_MEIS1:-1.01116114406;TAL1_TCF{3,4,12}:-1.03419613455;POU5F1:-1.10934735218;PAX6:-1.14797946713;HNF4A_NR2F1,2:-1.15039343831;HNF1A:-1.15722140928;SOX2:-1.16688034796;PRRX1,2:-1.2214259941;MYFfamily:-1.2351169369;HES1:-1.25394902063;GZF1:-1.33002643412;NFIX:-1.34528048653;FOX{F1,F2,J1}:-1.38274191411;NHLH1,2:-1.39128311316;RORA:-1.42917557536;T:-1.44269825571;MED-1{core}:-1.46097411214;ZBTB6:-1.52477168973;SOX5:-1.55483823707;RXR{A,B,G}_{NR1H2,PPAR}dimers:-1.56416511331;RREB1:-1.58713928405;ADNP_IRX_SIX_ZHX:-1.58980339014;CRX:-1.63062865673;PATZ1:-1.63111092571;ZNF384:-1.64845411441;NKX2-1,4:-1.65770123309;MTE{core}:-1.6903735573;E2F1..5:-1.69665764039;GATA6:-1.70266460914;TOPORS:-1.72301921003;TEAD1:-1.74359453119;CUX2:-1.76449671508;POU3F1..4:-1.78548498533;MTF1:-1.7954340696;GTF2A1,2:-1.81200286605;TLX1..3_NFIC{dimer}:-1.82212951586;TFAP2B:-1.8304567053;ZNF148:-1.8372659229;ZFP161:-1.8565904012;XCPE1{core}:-1.87567243322;ZEB1:-1.88135803574;GTF2I:-1.8874735255;SOX{8,9,10}:-1.90227426097;UFEwm:-1.91346376984;RFX1:-1.91465618401;BREu{core}:-1.94852941798;TP53:-1.96960638762;SP1:-1.97325075482;ZIC1..3:-1.97855667074;TFDP1:-2.01188026806;MAZ:-2.01671023313;NKX2-3_NKX2-5:-2.05062592464;MYOD1:-2.05825906025;FOXA2:-2.08235367036;TFAP2{A,C}:-2.1281339726;SNAI1..3:-2.1301519423;KLF4:-2.19386292454;GFI1B:-2.19395113573;CDC5L:-2.21063248717;FOXQ1:-2.21803718035;ARID5B:-2.23713908788;EVI1:-2.27450927618;GCM1,2:-2.28189452187;HIC1:-2.30553060668;TBX4,5:-2.31829085121;ELK1,4_GABP{A,B1}:-2.32469268197;ONECUT1,2:-2.35303649402;TEF:-2.37073229109;MYBL2:-2.41411476429;HOX{A4,D4}:-2.45563253332;AIRE:-2.50853687275;LMO2:-2.51706840092;ZNF423:-2.52066877811;bHLH_family:-2.54398455906;HAND1,2:-2.60319626017;EBF1:-2.6035788127;POU1F1:-2.69395753844;NFY{A,B,C}:-2.78105683633;PAX5:-2.83237109806;GFI1:-2.92184672088;FOX{I1,J2}:-2.95491436959;PBX1:-2.95904062292;NR5A1,2:-2.99039643821;SOX17:-3.05737919127;AR:-3.17560697141;NRF1:-3.30877459312;YY1:-3.30882961815;LEF1_TCF7_TCF7L1,2:-3.59014744991;LHX3,4:-3.80022280329;ZNF143:-3.88449802739 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11860-125A6;search_select_hide=table117:FF:11860-125A6 | |||
}} | }} |
Latest revision as of 18:24, 4 June 2020
Name: | CD14+ monocytes - treated with BCG, donor1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13465 |
Sample type: | primary cells |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13465
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13465
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0785 |
10 | 10 | 0.0213 |
100 | 100 | 0.916 |
101 | 101 | 0.931 |
102 | 102 | 0.913 |
103 | 103 | 0.314 |
104 | 104 | 0.526 |
105 | 105 | 0.17 |
106 | 106 | 6.21801e-4 |
107 | 107 | 0.18 |
108 | 108 | 0.964 |
109 | 109 | 0.248 |
11 | 11 | 0.121 |
110 | 110 | 0.146 |
111 | 111 | 0.0342 |
112 | 112 | 0.341 |
113 | 113 | 0.517 |
114 | 114 | 0.0143 |
115 | 115 | 0.206 |
116 | 116 | 0.73 |
117 | 117 | 0.0591 |
118 | 118 | 0.185 |
119 | 119 | 0.15 |
12 | 12 | 0.358 |
120 | 120 | 0.534 |
121 | 121 | 0.584 |
122 | 122 | 0.616 |
123 | 123 | 0.187 |
124 | 124 | 0.744 |
125 | 125 | 0.332 |
126 | 126 | 0.289 |
127 | 127 | 0.443 |
128 | 128 | 0.0379 |
129 | 129 | 0.338 |
13 | 13 | 0.111 |
130 | 130 | 0.186 |
131 | 131 | 0.94 |
132 | 132 | 0.113 |
133 | 133 | 0.476 |
134 | 134 | 0.474 |
135 | 135 | 0.652 |
136 | 136 | 0.981 |
137 | 137 | 0.0316 |
138 | 138 | 0.242 |
139 | 139 | 0.054 |
14 | 14 | 0.472 |
140 | 140 | 0.305 |
141 | 141 | 0.202 |
142 | 142 | 0.0698 |
143 | 143 | 0.0178 |
144 | 144 | 0.66 |
145 | 145 | 0.267 |
146 | 146 | 0.791 |
147 | 147 | 0.636 |
148 | 148 | 0.0133 |
149 | 149 | 0.861 |
15 | 15 | 0.147 |
150 | 150 | 0.397 |
151 | 151 | 0.353 |
152 | 152 | 0.243 |
153 | 153 | 0.828 |
154 | 154 | 0.563 |
155 | 155 | 0.88 |
156 | 156 | 0.638 |
157 | 157 | 0.679 |
158 | 158 | 0.0663 |
159 | 159 | 0.385 |
16 | 16 | 0.248 |
160 | 160 | 0.309 |
161 | 161 | 0.475 |
162 | 162 | 0.305 |
163 | 163 | 0.0594 |
164 | 164 | 0.103 |
165 | 165 | 0.194 |
166 | 166 | 0.645 |
167 | 167 | 0.157 |
168 | 168 | 0.108 |
169 | 169 | 0.00638 |
17 | 17 | 0.195 |
18 | 18 | 0.131 |
19 | 19 | 0.408 |
2 | 2 | 0.692 |
20 | 20 | 0.218 |
21 | 21 | 0.557 |
22 | 22 | 0.319 |
23 | 23 | 0.035 |
24 | 24 | 0.299 |
25 | 25 | 0.469 |
26 | 26 | 0.0384 |
27 | 27 | 0.663 |
28 | 28 | 0.481 |
29 | 29 | 0.23 |
3 | 3 | 0.094 |
30 | 30 | 0.457 |
31 | 31 | 0.786 |
32 | 32 | 0.972 |
33 | 33 | 0.26 |
34 | 34 | 0.729 |
35 | 35 | 0.154 |
36 | 36 | 0.0716 |
37 | 37 | 0.0794 |
38 | 38 | 0.38 |
39 | 39 | 0.802 |
4 | 4 | 0.835 |
40 | 40 | 0.217 |
41 | 41 | 0.0196 |
42 | 42 | 0.326 |
43 | 43 | 0.0322 |
44 | 44 | 0.901 |
45 | 45 | 0.786 |
46 | 46 | 0.147 |
47 | 47 | 0.452 |
48 | 48 | 0.436 |
49 | 49 | 0.129 |
5 | 5 | 0.321 |
50 | 50 | 0.98 |
51 | 51 | 0.439 |
52 | 52 | 0.369 |
53 | 53 | 0.471 |
54 | 54 | 0.379 |
55 | 55 | 0.454 |
56 | 56 | 0.663 |
57 | 57 | 0.749 |
58 | 58 | 0.149 |
59 | 59 | 0.228 |
6 | 6 | 0.787 |
60 | 60 | 0.0412 |
61 | 61 | 0.704 |
62 | 62 | 0.0767 |
63 | 63 | 0.413 |
64 | 64 | 0.395 |
65 | 65 | 0.212 |
66 | 66 | 0.26 |
67 | 67 | 0.492 |
68 | 68 | 0.947 |
69 | 69 | 0.331 |
7 | 7 | 0.266 |
70 | 70 | 0.0329 |
71 | 71 | 0.0318 |
72 | 72 | 0.193 |
73 | 73 | 0.185 |
74 | 74 | 0.0719 |
75 | 75 | 0.121 |
76 | 76 | 0.172 |
77 | 77 | 0.443 |
78 | 78 | 0.0905 |
79 | 79 | 0.481 |
8 | 8 | 0.34 |
80 | 80 | 0.22 |
81 | 81 | 0.318 |
82 | 82 | 0.144 |
83 | 83 | 0.0373 |
84 | 84 | 0.163 |
85 | 85 | 0.0297 |
86 | 86 | 0.0848 |
87 | 87 | 0.599 |
88 | 88 | 0.677 |
89 | 89 | 0.193 |
9 | 9 | 0.335 |
90 | 90 | 0.0786 |
91 | 91 | 0.354 |
92 | 92 | 0.214 |
93 | 93 | 0.513 |
94 | 94 | 0.0653 |
95 | 95 | 0.348 |
96 | 96 | 0.435 |
97 | 97 | 0.696 |
98 | 98 | 0.101 |
99 | 99 | 0.103 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13465
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011103 human CD14-positive monocytes - treated with BCG sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000766 (myeloid leukocyte)
0000219 (motile cell)
0000325 (stuff accumulating cell)
0000473 (defensive cell)
0000234 (phagocyte)
0000738 (leukocyte)
0002087 (nongranular leukocyte)
0000255 (eukaryotic cell)
0000576 (monocyte)
0000860 (classical monocyte)
0002057 (CD14-positive, CD16-negative classical monocyte)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000628 (Bacillus Calmette-Guerin treatment sample)
0011103 (human CD14-positive monocytes - treated with BCG sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)
CL:0002057 (CD14-positive, CD16-negative classical monocyte)