FF:10718-109I7: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005222 | ||
| | |accession_numbers=CAGE;DRX007835;DRR008707;DRZ000132;DRZ001517;DRZ011482;DRZ012867 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:8692 | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0101035,FF:0100741,FF:0100740 | |||
| | |comment= | ||
| | |created_by= | ||
|creation_date= | |||
|data_phase=2 | |||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr16:85932760..85932775,+!p1@IRF8!2.35!220.49!IRF8;;chr5:134369879..134369898,-!p2@PITX1!2.26!181.10!PITX1;;chr11:47400078..47400106,-!p1@SPI1!2.19!152.96!SPI1;;chr3:18486354..18486377,-!p2@SATB1!1.97!115.10!SATB1;;chr2:68592406..68592424,+!p1@PLEK!1.93!83.39!PLEK;;chr6:135502501..135502546,+!p1@MYB!1.90!92.59!MYB;;chr5:134369905..134369972,-!p1@PITX1!1.89!115.62!PITX1;;chr6:135502408..135502459,+!p2@MYB!1.88!85.43!MYB;;chr19:33793430..33793447,-!p1@CEBPA!1.86!288.02!CEBPA;;chr1:92951607..92951661,-!p1@GFI1!1.80!61.90!GFI1;;chr7:50344289..50344323,+!p1@IKZF1!1.79!60.37!IKZF1;;chr1:92949331..92949377,-!p2@GFI1!1.72!51.16!GFI1;;chr2:100759037..100759058,-!p2@AFF3!1.64!42.97!AFF3;;chr7:113726357..113726443,+!p1@FOXP2!1.60!65.99!FOXP2;;chr7:27205136..27205164,-!p1@HOXA9!1.60!38.88!HOXA9;;chr12:54778471..54778528,-!p1@ZNF385A!1.60!38.88!ZNF385A;;chr10:135044190..135044229,+!p3@UTF1!1.59!37.86!UTF1;;chr2:100759010..100759035,-!p1@AFF3!1.58!37.34!AFF3;;chr6:135516877..135516900,+!p5@MYB!1.55!34.79!MYB;;chr3:18467290..18467311,-!p8@SATB1!1.50!30.69!SATB1;;chr10:31288398..31288455,-!p2@ZNF438!1.44!30.69!ZNF438;;chr2:145277640..145277771,-!p1@ZEB2!1.43!335.59!ZEB2;;chr10:124907645..124907660,+!p1@HMX2!1.42!25.58!HMX2;;chr2:172949484..172949522,+!p1@DLX1!1.39!23.53!DLX1;;chr19:13213662..13213686,-!p1@LYL1!1.38!33.76!LYL1;;chr1:25256756..25256774,-!p1@RUNX3!1.35!39.90!RUNX3;;chr1:25291475..25291511,-!p2@RUNX3!1.33!20.46!RUNX3;;chr6:391743..391759,+!p1@IRF4!1.33!20.46!IRF4;;chr11:47400062..47400077,-!p2@SPI1!1.31!19.44!SPI1;;chr7:27213893..27213954,-!p1@HOXA10!1.29!18.42!HOXA10;;chr7:50343634..50343717,+!p2@IKZF1!1.29!18.42!IKZF1;;chr2:102091566..102091581,-!p1@RFX8!1.29!18.42!RFX8;;chr15:76629123..76629151,+!p1@ISL2!1.28!19.95!ISL2;;chr7:50344251..50344288,+!p3@IKZF1!1.26!17.39!IKZF1;;chr19:13213704..13213726,-!p3@LYL1!1.25!22.00!LYL1;;chrY:21906594..21906622,-!p1@KDM5D!1.25!16.88!KDM5D;;chr5:88178983..88179012,-!p1@MEF2C!1.23!120.22!MEF2C;;chr6:135502472..135502489,+!p3@MYB!1.23!15.86!MYB;;chr1:92952473..92952489,-!p3@GFI1!1.23!15.86!GFI1;;chr19:50432453..50432468,+!p1@ATF5!1.21!825.68!ATF5;;chr2:239148671..239148686,-!p1@HES6!1.21!55.76!HES6;;chr7:115670804..115670825,-!p1@TFEC!1.21!15.35!TFEC;;chr7:128577972..128578047,+!p1@IRF5!1.20!23.53!IRF5;;chr7:27205106..27205134,-!p2@HOXA9!1.19!14.32!HOXA9;;chr6:45390269..45390298,+!p5@RUNX2!1.18!23.53!RUNX2;;chr6:45390025..45390076,+!p2@RUNX2!1.17!33.25!RUNX2;;chr10:124895472..124895508,+!p1@HMX3!1.17!13.81!HMX3;;chr6:135516909..135516925,+!p6@MYB!1.14!12.79!MYB;;chr2:145282041..145282092,-!p8@ZEB2!1.13!18.93!ZEB2;;chrX:119384749..119384763,+!p4@ZBTB33!1.13!16.37!ZBTB33;;chr14:75988771..75988826,+!p1@BATF!1.11!15.86!BATF;;chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!1.11!11.77!MEF2B;;chr11:47399996..47400014,-!p4@SPI1!1.11!11.77!SPI1;;chr16:54320646..54320672,-!p2@IRX3!1.08!16.88!IRX3;;chr10:124907876..124907888,+!p5@HMX2!1.07!10.74!HMX2;;chrX:106960221..106960236,-!p3@TSC22D3!1.06!29.16!TSC22D3;;chr6:45390002..45390023,+!p6@RUNX2!1.06!18.42!RUNX2;;chr19:45579725..45579743,-!p1@ZNF296!1.05!47.06!ZNF296;;chr2:66662249..66662267,+!p2@MEIS1!1.05!39.90!MEIS1;;chr5:176738887..176738934,-!p1@MXD3!1.04!67.02!MXD3;;chr2:100759060..100759073,-!p8@AFF3!1.03!9.72!AFF3;;chr3:18466787..18466839,-!p1@SATB1!1.02!43.48!SATB1;;chr19:33865009..33865090,+!p3@CEBPG!1.01!12.28!CEBPG;;chr6:45390300..45390335,+!p4@RUNX2!1.00!14.32!RUNX2;;chr11:128563948..128564003,+!p1@FLI1!0.99!107.43!FLI1;;chr2:145277882..145277967,-!p3@ZEB2!0.99!15.35!ZEB2;;chr2:68592394..68592405,+!p2@PLEK!0.96!8.19!PLEK;;chr16:54319010..54319041,-!p8@IRX3!0.96!8.19!IRX3;;chr18:55102598..55102623,+!p1@ONECUT2!0.96!8.19!ONECUT2;;chr1:92949505..92949543,-!p5@GFI1!0.96!8.19!GFI1;;chr19:20011744..20011770,+!p1@ZNF93!0.94!31.21!ZNF93;;chr18:55102628..55102646,+!p2@ONECUT2!0.94!7.67!ONECUT2;;chr3:157824001..157824078,-!p2@SHOX2!0.94!7.67!SHOX2;;chr7:73038839..73038862,-!p1@MLXIPL!0.94!7.67!MLXIPL;;chr5:134369848..134369853,-!p6@PITX1!0.91!7.16!PITX1;;chr19:13213954..13214021,-!p4@LYL1!0.91!7.16!LYL1;;chr10:31288370..31288393,-!p3@ZNF438!0.91!7.16!ZNF438;;chr2:100759076..100759088,-!p10@AFF3!0.91!7.16!AFF3;;chr2:60780753..60780800,-!p1@BCL11A!0.90!35.81!BCL11A;;chr20:50159198..50159299,-!p1@NFATC2!0.90!10.23!NFATC2;;chr2:100758991..100759009,-!p3@AFF3!0.88!6.65!AFF3;;chr11:47400045..47400060,-!p6@SPI1!0.88!6.65!SPI1;;chr1:156470515..156470542,-!p2@MEF2D!0.87!35.30!MEF2D;;chr17:79881332..79881348,-!p3@MAFG!0.87!9.72!MAFG;;chrX:119384566..119384585,+!p2@ZBTB33!0.86!10.23!ZBTB33;;chr16:29817841..29817865,+!p1@MAZ!0.85!140.17!MAZ;;chr16:54320675..54320715,-!p1@IRX3!0.85!13.81!IRX3;;chr7:113726226..113726245,+!p3@FOXP2!0.85!6.14!FOXP2;;chr7:35293685..35293718,-!p1@TBX20!0.85!6.14!TBX20;;chr11:47400032..47400043,-!p5@SPI1!0.85!6.14!SPI1;;chr16:54320617..54320643,-!p3@IRX3!0.84!7.67!IRX3;;chr11:19263160..19263176,-!p1@E2F8!0.82!6.65!E2F8;;chr11:47399947..47399961,-!p3@SPI1!0.82!5.63!SPI1;;chr2:172967621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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 40: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/biphenotypic%2520B%2520myelomonocytic%2520leukemia%2520cell%2520line%253aMV-4-11.CNhs11845.10718-109I7.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/biphenotypic%2520B%2520myelomonocytic%2520leukemia%2520cell%2520line%253aMV-4-11.CNhs11845.10718-109I7.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/biphenotypic%2520B%2520myelomonocytic%2520leukemia%2520cell%2520line%253aMV-4-11.CNhs11845.10718-109I7.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/biphenotypic%2520B%2520myelomonocytic%2520leukemia%2520cell%2520line%253aMV-4-11.CNhs11845.10718-109I7.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/biphenotypic%2520B%2520myelomonocytic%2520leukemia%2520cell%2520line%253aMV-4-11.CNhs11845.10718-109I7.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10718-109I7 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0100740;;FF:0100741 | |||
|is_obsolete= | |||
|library_id=CNhs11845 | |||
|library_id_phase_based=2:CNhs11845 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10718 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10718 | |||
|name=biphenotypic B myelomonocytic leukemia cell line:MV-4-11 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11845,LSID829,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,-0.160318030086386,0,0.0286648221204145,0.0829054522723895,0,0,0,0,0,0,0,0,0,0.179428944922886,0,0,0,0.330448160479282,0,0,0,0,0,0.305971600290474,0,0,0.173070364535066,0,0,0,0,0,0,0,0,0,0,0,0,0.125896272826973,0.179428944922886,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0.179428944922886,0,0,0,0.512541671662957,0,0,-0.097343627213097,0,0,0,0,0,0,0,0,0,0,0.609534032905562,0,0,0,0,0,0,0.0517580024673543,0,0,0.0932879551336743,0,0,0,-0.552571649267773,0.089714472461443,0,0,0.191706483479549,0.183284086218356,0.089714472461443,0,0,0,0.305894145320825,0.193122857074402,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0566398832345035,0.179428944922886,0,0,0,-0.0143476878436194,0,0,0.174113172612208,0,0,0 | |||
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| |||
|rna_box=109 | |||
|rna_catalog_number= | |||
|rna_concentration=0.57232 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.1 | |||
|rna_od260/280=2.1 | |||
|rna_position=I7 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=109I7 | |||
|rna_weight_ug=26.89904 | |||
|sample_age=10 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=CRL-9591 | |||
|sample_cell_line=MV-4-11 | |||
|sample_cell_lot= | |||
|sample_cell_type=myeloid progenitor cell | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=ATCC | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=biphenotypic B myelomonocytic leukemia | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;8.9722498755381e-251!GO:0043227;membrane-bound organelle;2.13033972869218e-225!GO:0043231;intracellular membrane-bound organelle;5.63488981446591e-225!GO:0043226;organelle;8.36815349715517e-213!GO:0043229;intracellular organelle;5.03058051087888e-212!GO:0005737;cytoplasm;1.29589672408704e-153!GO:0044422;organelle part;6.26783069520804e-149!GO:0044446;intracellular organelle part;5.91164444421944e-147!GO:0044237;cellular metabolic process;4.13196751668527e-118!GO:0044444;cytoplasmic part;8.67008409324365e-117!GO:0044238;primary metabolic process;2.94682856903347e-113!GO:0032991;macromolecular complex;3.43670619111158e-111!GO:0005634;nucleus;1.14218623204961e-108!GO:0043170;macromolecule metabolic process;4.05101802693054e-104!GO:0030529;ribonucleoprotein complex;7.8997569980511e-97!GO:0044428;nuclear part;2.29226590886758e-88!GO:0043233;organelle lumen;1.31651380480855e-81!GO:0031974;membrane-enclosed lumen;1.31651380480855e-81!GO:0003723;RNA binding;1.35962864304478e-81!GO:0005739;mitochondrion;5.40294655320315e-78!GO:0043283;biopolymer metabolic process;1.43035702254449e-65!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.27034874475197e-64!GO:0010467;gene expression;2.38369959507304e-62!GO:0006412;translation;7.51212315532704e-62!GO:0005840;ribosome;1.25499382020015e-57!GO:0043234;protein complex;1.27836308142799e-55!GO:0006396;RNA processing;1.6989825173819e-55!GO:0005515;protein binding;6.82759953072474e-53!GO:0044429;mitochondrial part;9.38755327576874e-52!GO:0003735;structural constituent of ribosome;1.62935263470297e-50!GO:0031981;nuclear lumen;1.95028191321517e-50!GO:0044249;cellular biosynthetic process;6.62656185459755e-50!GO:0019538;protein metabolic process;2.23675836425133e-48!GO:0009058;biosynthetic process;4.14554114515557e-48!GO:0009059;macromolecule biosynthetic process;3.07924570544957e-47!GO:0016071;mRNA metabolic process;6.0046242289805e-46!GO:0031967;organelle envelope;8.67150791021364e-46!GO:0031975;envelope;2.06876587847802e-45!GO:0006259;DNA metabolic process;2.29510465583368e-45!GO:0044267;cellular protein metabolic process;2.43210696262794e-45!GO:0044260;cellular macromolecule metabolic process;3.20400547233756e-45!GO:0033279;ribosomal subunit;2.52139016714365e-44!GO:0003676;nucleic acid binding;2.89751406804498e-43!GO:0031090;organelle membrane;5.76616568420161e-42!GO:0033036;macromolecule localization;2.88068486821867e-41!GO:0008380;RNA splicing;5.49366273817282e-40!GO:0006397;mRNA processing;1.55851196759683e-39!GO:0015031;protein transport;6.22972949168461e-39!GO:0016043;cellular component organization and biogenesis;6.73983230303205e-39!GO:0045184;establishment of protein localization;1.64271325103298e-37!GO:0008104;protein localization;3.98801280015749e-37!GO:0005829;cytosol;3.98801280015749e-37!GO:0006996;organelle organization and biogenesis;3.94382419027672e-35!GO:0065003;macromolecular complex assembly;1.25346972065018e-34!GO:0007049;cell cycle;2.704026079488e-34!GO:0022613;ribonucleoprotein complex biogenesis and assembly;7.13871198519208e-34!GO:0046907;intracellular transport;9.11799456104651e-33!GO:0043228;non-membrane-bound organelle;1.83975785909321e-32!GO:0043232;intracellular non-membrane-bound organelle;1.83975785909321e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.87028317441781e-32!GO:0005740;mitochondrial envelope;1.93820855969417e-32!GO:0005654;nucleoplasm;6.33250505267616e-32!GO:0019866;organelle inner membrane;1.21263149411696e-31!GO:0022607;cellular component assembly;1.05689546730519e-30!GO:0031966;mitochondrial membrane;4.63869955011188e-30!GO:0005681;spliceosome;7.52807382282791e-30!GO:0016070;RNA metabolic process;1.43644641055097e-29!GO:0006886;intracellular protein transport;2.99500658537714e-29!GO:0000166;nucleotide binding;7.65383657396648e-29!GO:0022402;cell cycle process;1.24520547786115e-28!GO:0005743;mitochondrial inner membrane;1.33842805106353e-28!GO:0005694;chromosome;3.5995424164694e-27!GO:0006974;response to DNA damage stimulus;4.34733291136461e-27!GO:0044445;cytosolic part;4.7800391888877e-27!GO:0051649;establishment of cellular localization;5.96729085105176e-26!GO:0000278;mitotic cell cycle;1.95861399538634e-25!GO:0051641;cellular localization;3.10592703996464e-25!GO:0044427;chromosomal part;6.91484872035231e-25!GO:0044451;nucleoplasm part;1.24641459427583e-24!GO:0051276;chromosome organization and biogenesis;1.28956663175566e-23!GO:0006119;oxidative phosphorylation;1.33492777111392e-23!GO:0006281;DNA repair;2.65936055672397e-23!GO:0031980;mitochondrial lumen;3.7354992587636e-23!GO:0005759;mitochondrial matrix;3.7354992587636e-23!GO:0015935;small ribosomal subunit;6.77924204645288e-23!GO:0044455;mitochondrial membrane part;9.74315419281783e-23!GO:0015934;large ribosomal subunit;1.22891451594053e-22!GO:0022403;cell cycle phase;3.16598588729574e-22!GO:0022618;protein-RNA complex assembly;5.37033713831143e-21!GO:0016874;ligase activity;8.14818614568252e-21!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;1.15474140769922e-20!GO:0016817;hydrolase activity, acting on acid anhydrides;1.22367299104353e-20!GO:0016462;pyrophosphatase activity;1.89996542571857e-20!GO:0000087;M phase of mitotic cell cycle;4.76386025256338e-20!GO:0032553;ribonucleotide binding;4.91659817731729e-20!GO:0032555;purine ribonucleotide binding;4.91659817731729e-20!GO:0007067;mitosis;8.77186027732141e-20!GO:0005524;ATP binding;1.05066525059774e-19!GO:0017076;purine nucleotide binding;1.32689267086483e-19!GO:0044265;cellular macromolecule catabolic process;2.00801136862566e-19!GO:0017111;nucleoside-triphosphatase activity;2.4532706301519e-19!GO:0032559;adenyl ribonucleotide binding;4.39421641349437e-19!GO:0005730;nucleolus;5.19671438527608e-19!GO:0005746;mitochondrial respiratory chain;8.87788914468373e-19!GO:0006325;establishment and/or maintenance of chromatin architecture;1.44000460160955e-18!GO:0000279;M phase;1.57122356350976e-18!GO:0030554;adenyl nucleotide binding;2.11173320583401e-18!GO:0009719;response to endogenous stimulus;3.07474788447753e-18!GO:0006512;ubiquitin cycle;4.86557824366539e-18!GO:0043285;biopolymer catabolic process;5.2912786327103e-18!GO:0044248;cellular catabolic process;5.46566140010639e-18!GO:0006323;DNA packaging;7.50763547220484e-18!GO:0008134;transcription factor binding;1.44002960028139e-17!GO:0048770;pigment granule;2.36129724276133e-17!GO:0042470;melanosome;2.36129724276133e-17!GO:0006457;protein folding;4.32460933633778e-17!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.59538350301629e-17!GO:0008135;translation factor activity, nucleic acid binding;5.65308807044023e-17!GO:0009057;macromolecule catabolic process;7.32768462251467e-17!GO:0051301;cell division;1.51907172193685e-16!GO:0051186;cofactor metabolic process;1.66642194732377e-16!GO:0050136;NADH dehydrogenase (quinone) activity;3.03735339781699e-16!GO:0003954;NADH dehydrogenase activity;3.03735339781699e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.03735339781699e-16!GO:0006605;protein targeting;4.00164037661825e-16!GO:0005761;mitochondrial ribosome;5.25573751888278e-16!GO:0000313;organellar ribosome;5.25573751888278e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;5.4006132501097e-16!GO:0006260;DNA replication;5.54387942675471e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);5.85311564780109e-16!GO:0000502;proteasome complex (sensu Eukaryota);7.91972942098592e-16!GO:0016887;ATPase activity;2.42458854890937e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;2.93810658667252e-15!GO:0019941;modification-dependent protein catabolic process;3.73425651837121e-15!GO:0043632;modification-dependent macromolecule catabolic process;3.73425651837121e-15!GO:0006511;ubiquitin-dependent protein catabolic process;4.70108744548127e-15!GO:0044257;cellular protein catabolic process;6.04289587394166e-15!GO:0042623;ATPase activity, coupled;6.76940243157753e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.07945402741276e-14!GO:0000375;RNA splicing, via transesterification reactions;1.07945402741276e-14!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.07945402741276e-14!GO:0051726;regulation of cell cycle;1.31525723727942e-14!GO:0042775;organelle ATP synthesis coupled electron transport;2.06268812522344e-14!GO:0042773;ATP synthesis coupled electron transport;2.06268812522344e-14!GO:0043412;biopolymer modification;2.07485838943614e-14!GO:0044453;nuclear membrane part;2.48148969670232e-14!GO:0012505;endomembrane system;2.50478345285882e-14!GO:0000074;regulation of progression through cell cycle;2.52418507869589e-14!GO:0030964;NADH dehydrogenase complex (quinone);3.07768459920959e-14!GO:0045271;respiratory chain complex I;3.07768459920959e-14!GO:0005747;mitochondrial respiratory chain complex I;3.07768459920959e-14!GO:0006732;coenzyme metabolic process;4.0791797174607e-14!GO:0042254;ribosome biogenesis and assembly;4.19273474425072e-14!GO:0005635;nuclear envelope;4.28405940917807e-14!GO:0000785;chromatin;6.28479593897424e-14!GO:0006913;nucleocytoplasmic transport;7.41377181423499e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;1.12202146126902e-13!GO:0012501;programmed cell death;1.15735605836479e-13!GO:0016604;nuclear body;1.2728197062112e-13!GO:0006915;apoptosis;1.48411409788648e-13!GO:0051169;nuclear transport;1.69874088644536e-13!GO:0051082;unfolded protein binding;1.83324626855607e-13!GO:0003743;translation initiation factor activity;2.64146001477701e-13!GO:0006413;translational initiation;2.64146001477701e-13!GO:0031965;nuclear membrane;3.57836963334726e-13!GO:0006399;tRNA metabolic process;5.34252778859171e-13!GO:0006333;chromatin assembly or disassembly;5.62436059556465e-13!GO:0008219;cell death;8.60292255398464e-13!GO:0016265;death;8.60292255398464e-13!GO:0030163;protein catabolic process;9.96640450777105e-13!GO:0006446;regulation of translational initiation;1.46235948331131e-12!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.40443642318093e-12!GO:0016568;chromatin modification;2.55556266730339e-12!GO:0006464;protein modification process;2.65572305884984e-12!GO:0050657;nucleic acid transport;4.65846689993033e-12!GO:0051236;establishment of RNA localization;4.65846689993033e-12!GO:0050658;RNA transport;4.65846689993033e-12!GO:0004386;helicase activity;5.39378591903228e-12!GO:0006403;RNA localization;6.27377250734093e-12!GO:0044432;endoplasmic reticulum part;9.47826819349499e-12!GO:0065002;intracellular protein transport across a membrane;1.06427708577269e-11!GO:0005643;nuclear pore;2.90378301330973e-11!GO:0009056;catabolic process;3.91337583111536e-11!GO:0065004;protein-DNA complex assembly;4.15746139730088e-11!GO:0009259;ribonucleotide metabolic process;4.72342841316611e-11!GO:0006163;purine nucleotide metabolic process;4.72342841316611e-11!GO:0017038;protein import;5.96907726707076e-11!GO:0006164;purine nucleotide biosynthetic process;7.35748221267235e-11!GO:0008026;ATP-dependent helicase activity;7.47066013546499e-11!GO:0043687;post-translational protein modification;9.08742438735374e-11!GO:0016607;nuclear speck;1.20530463007152e-10!GO:0005783;endoplasmic reticulum;1.91784247224408e-10!GO:0003712;transcription cofactor activity;2.0319294732883e-10!GO:0051028;mRNA transport;2.2615343258296e-10!GO:0009260;ribonucleotide biosynthetic process;2.54425529806442e-10!GO:0008565;protein transporter activity;2.54425529806442e-10!GO:0051188;cofactor biosynthetic process;2.9745877106066e-10!GO:0009150;purine ribonucleotide metabolic process;3.67187206667861e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.67187206667861e-10!GO:0004812;aminoacyl-tRNA ligase activity;3.67187206667861e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.67187206667861e-10!GO:0016192;vesicle-mediated transport;4.05707419549732e-10!GO:0050794;regulation of cellular process;5.13241030638721e-10!GO:0009152;purine ribonucleotide biosynthetic process;5.58228562146404e-10!GO:0016787;hydrolase activity;6.42371490917522e-10!GO:0046930;pore complex;6.6723659211587e-10!GO:0043038;amino acid activation;8.85283496710928e-10!GO:0006418;tRNA aminoacylation for protein translation;8.85283496710928e-10!GO:0043039;tRNA aminoacylation;8.85283496710928e-10!GO:0043566;structure-specific DNA binding;1.04885501636971e-09!GO:0031497;chromatin assembly;1.08575021211866e-09!GO:0048193;Golgi vesicle transport;1.11333286431001e-09!GO:0003697;single-stranded DNA binding;1.36847323987945e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.59647744559017e-09!GO:0019222;regulation of metabolic process;1.93184470262731e-09!GO:0000775;chromosome, pericentric region;2.04257353500616e-09!GO:0006364;rRNA processing;2.12603748896338e-09!GO:0006334;nucleosome assembly;2.17718813498068e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.18518571767663e-09!GO:0016072;rRNA metabolic process;2.50028438109438e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.88994827773975e-09!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.92617001921296e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;3.18691491414414e-09!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.70322513029755e-09!GO:0009055;electron carrier activity;4.80198283600941e-09!GO:0016779;nucleotidyltransferase activity;5.29293117566293e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;5.38973998125767e-09!GO:0009060;aerobic respiration;6.73289997044979e-09!GO:0008639;small protein conjugating enzyme activity;8.35798105822791e-09!GO:0005789;endoplasmic reticulum membrane;1.05593847609955e-08!GO:0042981;regulation of apoptosis;1.32538974757266e-08!GO:0015986;ATP synthesis coupled proton transport;1.52358632503851e-08!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.52358632503851e-08!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;1.57530345652029e-08!GO:0043067;regulation of programmed cell death;1.77139429370834e-08!GO:0005819;spindle;1.87270677694028e-08!GO:0009142;nucleoside triphosphate biosynthetic process;1.87404769083287e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.87404769083287e-08!GO:0004842;ubiquitin-protein ligase activity;1.87404769083287e-08!GO:0009199;ribonucleoside triphosphate metabolic process;2.17734348019225e-08!GO:0009141;nucleoside triphosphate metabolic process;2.20171204359579e-08!GO:0006461;protein complex assembly;2.40227645890793e-08!GO:0019787;small conjugating protein ligase activity;2.42507604218602e-08!GO:0015078;hydrogen ion transmembrane transporter activity;3.17298076969756e-08!GO:0009108;coenzyme biosynthetic process;3.33500585636032e-08!GO:0007005;mitochondrion organization and biogenesis;3.49770342018383e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;3.66556291936246e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;3.66556291936246e-08!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.13197252238084e-08!GO:0009144;purine nucleoside triphosphate metabolic process;4.13197252238084e-08!GO:0005839;proteasome core complex (sensu Eukaryota);4.36763722787712e-08!GO:0009117;nucleotide metabolic process;5.08097311286653e-08!GO:0016740;transferase activity;5.20220308563769e-08!GO:0006793;phosphorus metabolic process;5.82182064028927e-08!GO:0006796;phosphate metabolic process;5.82182064028927e-08!GO:0019829;cation-transporting ATPase activity;6.57022794144059e-08!GO:0051246;regulation of protein metabolic process;6.6211316551912e-08!GO:0045333;cellular respiration;6.96711772873527e-08!GO:0006261;DNA-dependent DNA replication;7.53194146909368e-08!GO:0031323;regulation of cellular metabolic process;8.46005133036186e-08!GO:0051170;nuclear import;8.50135871905692e-08!GO:0015630;microtubule cytoskeleton;1.07043225664546e-07!GO:0006754;ATP biosynthetic process;1.20761383879538e-07!GO:0006753;nucleoside phosphate metabolic process;1.20761383879538e-07!GO:0005794;Golgi apparatus;1.22992974090886e-07!GO:0006366;transcription from RNA polymerase II promoter;1.28450230468823e-07!GO:0051329;interphase of mitotic cell cycle;1.73296096281197e-07!GO:0006606;protein import into nucleus;1.82116947735385e-07!GO:0046034;ATP metabolic process;1.8856835767533e-07!GO:0006752;group transfer coenzyme metabolic process;2.13351474443524e-07!GO:0005813;centrosome;2.75647817130591e-07!GO:0005815;microtubule organizing center;2.9745457998216e-07!GO:0004298;threonine endopeptidase activity;3.01264205891054e-07!GO:0050789;regulation of biological process;3.38524384499008e-07!GO:0016469;proton-transporting two-sector ATPase complex;3.85481065375731e-07!GO:0005793;ER-Golgi intermediate compartment;4.77636463693581e-07!GO:0000245;spliceosome assembly;4.8095693200248e-07!GO:0032446;protein modification by small protein conjugation;4.9860124524359e-07!GO:0016881;acid-amino acid ligase activity;5.21124210218311e-07!GO:0051325;interphase;5.40428556705231e-07!GO:0005768;endosome;5.9556578527732e-07!GO:0006099;tricarboxylic acid cycle;6.70078719220149e-07!GO:0046356;acetyl-CoA catabolic process;6.70078719220149e-07!GO:0016310;phosphorylation;7.06894647252797e-07!GO:0016567;protein ubiquitination;7.78969911684236e-07!GO:0006084;acetyl-CoA metabolic process;9.64694198904928e-07!GO:0009109;coenzyme catabolic process;1.00177214065063e-06!GO:0005773;vacuole;1.00375468092387e-06!GO:0000075;cell cycle checkpoint;1.09255212985678e-06!GO:0006350;transcription;1.18650965868727e-06!GO:0000786;nucleosome;1.26092476230968e-06!GO:0045259;proton-transporting ATP synthase complex;1.26092476230968e-06!GO:0005762;mitochondrial large ribosomal subunit;1.3659356630588e-06!GO:0000315;organellar large ribosomal subunit;1.3659356630588e-06!GO:0048475;coated membrane;1.58457890783546e-06!GO:0030117;membrane coat;1.58457890783546e-06!GO:0045786;negative regulation of progression through cell cycle;1.61523439160257e-06!GO:0030120;vesicle coat;1.62638436653479e-06!GO:0030662;coated vesicle membrane;1.62638436653479e-06!GO:0000323;lytic vacuole;1.77202394048504e-06!GO:0005764;lysosome;1.77202394048504e-06!GO:0003713;transcription coactivator activity;1.83574374183925e-06!GO:0043623;cellular protein complex assembly;2.01875635008772e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.64833745045462e-06!GO:0005667;transcription factor complex;2.66505172695002e-06!GO:0003899;DNA-directed RNA polymerase activity;2.74449573794157e-06!GO:0010468;regulation of gene expression;3.74250981335373e-06!GO:0006401;RNA catabolic process;4.37008001201564e-06!GO:0065009;regulation of a molecular function;6.08931202395384e-06!GO:0003724;RNA helicase activity;6.1409375216271e-06!GO:0007051;spindle organization and biogenesis;7.77309953996435e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;8.43456366437883e-06!GO:0007088;regulation of mitosis;8.53178470756788e-06!GO:0051187;cofactor catabolic process;8.75008415487738e-06!GO:0006082;organic acid metabolic process;9.29332179428657e-06!GO:0051168;nuclear export;1.01351253741504e-05!GO:0019752;carboxylic acid metabolic process;1.01520549030512e-05!GO:0006302;double-strand break repair;1.07675217856001e-05!GO:0009165;nucleotide biosynthetic process;1.08214444755133e-05!GO:0000151;ubiquitin ligase complex;1.23337161158848e-05!GO:0003690;double-stranded DNA binding;1.28033854675022e-05!GO:0043069;negative regulation of programmed cell death;1.31046949257814e-05!GO:0016491;oxidoreductase activity;1.40031659748196e-05!GO:0006613;cotranslational protein targeting to membrane;1.50661181992216e-05!GO:0016563;transcription activator activity;1.60159584315688e-05!GO:0043066;negative regulation of apoptosis;1.63501738697997e-05!GO:0031324;negative regulation of cellular metabolic process;1.92687739503241e-05!GO:0006916;anti-apoptosis;2.1596016173924e-05!GO:0048523;negative regulation of cellular process;2.29332366022264e-05!GO:0051427;hormone receptor binding;2.38783900651081e-05!GO:0008094;DNA-dependent ATPase activity;2.45666997442535e-05!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.5331119757326e-05!GO:0003677;DNA binding;2.70519134600365e-05!GO:0006888;ER to Golgi vesicle-mediated transport;2.95618175223932e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;3.07317913416925e-05!GO:0006310;DNA recombination;3.36766755661201e-05!GO:0007059;chromosome segregation;3.43264629116735e-05!GO:0005657;replication fork;3.51248502975747e-05!GO:0003729;mRNA binding;4.51274810311259e-05!GO:0003684;damaged DNA binding;4.79705750366762e-05!GO:0016363;nuclear matrix;4.96174173897591e-05!GO:0016741;transferase activity, transferring one-carbon groups;4.98984329270454e-05!GO:0035257;nuclear hormone receptor binding;4.99135599798058e-05!GO:0005770;late endosome;5.51377090481742e-05!GO:0043021;ribonucleoprotein binding;5.55030355444775e-05!GO:0000314;organellar small ribosomal subunit;5.65545194957025e-05!GO:0005763;mitochondrial small ribosomal subunit;5.65545194957025e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;6.11254778949837e-05!GO:0015399;primary active transmembrane transporter activity;6.11254778949837e-05!GO:0016564;transcription repressor activity;6.34380415548658e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;6.62498793896673e-05!GO:0008168;methyltransferase activity;6.90771493890106e-05!GO:0006950;response to stress;7.18469745602066e-05!GO:0006091;generation of precursor metabolites and energy;7.84252836110793e-05!GO:0008033;tRNA processing;7.85258005339862e-05!GO:0000082;G1/S transition of mitotic cell cycle;8.28317344813783e-05!GO:0004518;nuclease activity;8.76836056431981e-05!GO:0043681;protein import into mitochondrion;9.21901717653138e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;9.776877297902e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.000104640388584818!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000107769081291696!GO:0006414;translational elongation;0.000108298112296833!GO:0006818;hydrogen transport;0.000121344945336184!GO:0000776;kinetochore;0.000141453839545904!GO:0015992;proton transport;0.000151787631577658!GO:0006402;mRNA catabolic process;0.000152578616194598!GO:0008186;RNA-dependent ATPase activity;0.000165117448171214!GO:0048519;negative regulation of biological process;0.000168704481232853!GO:0008632;apoptotic program;0.000194244781664937!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.000204621135901539!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000217828344560777!GO:0005885;Arp2/3 protein complex;0.000218986726344062!GO:0006612;protein targeting to membrane;0.000225428600796939!GO:0005788;endoplasmic reticulum lumen;0.000225867776275993!GO:0006417;regulation of translation;0.000237091561494474!GO:0019899;enzyme binding;0.000247812539813432!GO:0003682;chromatin binding;0.00024877044065421!GO:0003678;DNA helicase activity;0.00024877044065421!GO:0006626;protein targeting to mitochondrion;0.000253208885262695!GO:0006520;amino acid metabolic process;0.000286683239572732!GO:0000049;tRNA binding;0.000318323574421547!GO:0005637;nuclear inner membrane;0.000321771359262568!GO:0032774;RNA biosynthetic process;0.000321893156695518!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000364782022419421!GO:0045454;cell redox homeostasis;0.00036908746893624!GO:0007093;mitotic cell cycle checkpoint;0.000370201699780465!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000376100590052754!GO:0006351;transcription, DNA-dependent;0.000401951580206663!GO:0007006;mitochondrial membrane organization and biogenesis;0.000412050261282947!GO:0008654;phospholipid biosynthetic process;0.000412141944295423!GO:0065007;biological regulation;0.000427695781149352!GO:0009892;negative regulation of metabolic process;0.00043321262381813!GO:0006289;nucleotide-excision repair;0.000441904107707642!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000443024196965083!GO:0045449;regulation of transcription;0.000458096254881513!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000462343970368432!GO:0006839;mitochondrial transport;0.000470141460164086!GO:0007050;cell cycle arrest;0.000483604123359631!GO:0004004;ATP-dependent RNA helicase activity;0.000490552245915329!GO:0032508;DNA duplex unwinding;0.000504796501885038!GO:0032392;DNA geometric change;0.000504796501885038!GO:0003714;transcription corepressor activity;0.00050943500209528!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00050943500209528!GO:0050790;regulation of catalytic activity;0.000511969069542589!GO:0006405;RNA export from nucleus;0.000518884068380609!GO:0044440;endosomal part;0.000521653617068602!GO:0010008;endosome membrane;0.000521653617068602!GO:0004527;exonuclease activity;0.000637038747287894!GO:0005769;early endosome;0.000639860757524031!GO:0046483;heterocycle metabolic process;0.000684036635546236!GO:0006383;transcription from RNA polymerase III promoter;0.000701337972678234!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.000761745159502145!GO:0046489;phosphoinositide biosynthetic process;0.000762044137429669!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000774507708540653!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000774507708540653!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000774507708540653!GO:0005798;Golgi-associated vesicle;0.00078719446846688!GO:0016853;isomerase activity;0.000803527660527312!GO:0031968;organelle outer membrane;0.00080963350423924!GO:0043065;positive regulation of apoptosis;0.000812265840207818!GO:0006268;DNA unwinding during replication;0.000846661871084688!GO:0000059;protein import into nucleus, docking;0.000881848219749305!GO:0043492;ATPase activity, coupled to movement of substances;0.000915826722615725!GO:0046474;glycerophospholipid biosynthetic process;0.000983435612501254!GO:0043068;positive regulation of programmed cell death;0.000983435612501254!GO:0030880;RNA polymerase complex;0.00102754573873957!GO:0006650;glycerophospholipid metabolic process;0.00106309953104174!GO:0015631;tubulin binding;0.00110329081926084!GO:0030384;phosphoinositide metabolic process;0.00112150993359174!GO:0031072;heat shock protein binding;0.00112510513804605!GO:0019867;outer membrane;0.00112956391941222!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00113754528980391!GO:0030663;COPI coated vesicle membrane;0.00117519044491284!GO:0030126;COPI vesicle coat;0.00117519044491284!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00118287133007947!GO:0005684;U2-dependent spliceosome;0.00120327130053173!GO:0031326;regulation of cellular biosynthetic process;0.00128423327709044!GO:0006917;induction of apoptosis;0.0013803018206325!GO:0042802;identical protein binding;0.001444358566141!GO:0016481;negative regulation of transcription;0.00152946367179952!GO:0006338;chromatin remodeling;0.0016110762570149!GO:0043284;biopolymer biosynthetic process;0.00162358974644841!GO:0044452;nucleolar part;0.00175197440170814!GO:0003711;transcription elongation regulator activity;0.00175197440170814!GO:0032940;secretion by cell;0.00176020818239896!GO:0016197;endosome transport;0.00179896470369575!GO:0019843;rRNA binding;0.00181279208721385!GO:0012502;induction of programmed cell death;0.00185322209780894!GO:0015980;energy derivation by oxidation of organic compounds;0.00186268596288025!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00194355567622734!GO:0000428;DNA-directed RNA polymerase complex;0.00194355567622734!GO:0005741;mitochondrial outer membrane;0.00197842628500907!GO:0005758;mitochondrial intermembrane space;0.00220011666178734!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.00221801920562764!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00222930360866246!GO:0051052;regulation of DNA metabolic process;0.00234878789880221!GO:0005525;GTP binding;0.00237153730986264!GO:0031124;mRNA 3'-end processing;0.00258817113335214!GO:0004674;protein serine/threonine kinase activity;0.00276430489706994!GO:0046983;protein dimerization activity;0.00295473205675354!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00296015676417487!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00296015676417487!GO:0007034;vacuolar transport;0.00296015676417487!GO:0048500;signal recognition particle;0.00306511805882214!GO:0003924;GTPase activity;0.00307000203970751!GO:0000792;heterochromatin;0.00307300466727873!GO:0000922;spindle pole;0.00308475398843522!GO:0007052;mitotic spindle organization and biogenesis;0.00315775388849994!GO:0040029;regulation of gene expression, epigenetic;0.00317536064733528!GO:0016251;general RNA polymerase II transcription factor activity;0.00320811994316991!GO:0051252;regulation of RNA metabolic process;0.00321130135838968!GO:0006284;base-excision repair;0.0032147210224438!GO:0045045;secretory pathway;0.00330804042467865!GO:0000118;histone deacetylase complex;0.00330804042467865!GO:0031982;vesicle;0.00331638363921053!GO:0006506;GPI anchor biosynthetic process;0.0033608773922996!GO:0042393;histone binding;0.00336129903535443!GO:0051920;peroxiredoxin activity;0.00342211592540629!GO:0030658;transport vesicle membrane;0.0034558889172657!GO:0043414;biopolymer methylation;0.0034558889172657!GO:0048522;positive regulation of cellular process;0.00353752692871292!GO:0032200;telomere organization and biogenesis;0.00358931778696278!GO:0000723;telomere maintenance;0.00358931778696278!GO:0044262;cellular carbohydrate metabolic process;0.00362834175705519!GO:0051087;chaperone binding;0.0037451241776048!GO:0000228;nuclear chromosome;0.00375711358909117!GO:0006352;transcription initiation;0.00384305620490229!GO:0022890;inorganic cation transmembrane transporter activity;0.00384305620490229!GO:0009889;regulation of biosynthetic process;0.00417058396203939!GO:0051789;response to protein stimulus;0.00444579083555376!GO:0006986;response to unfolded protein;0.00444579083555376!GO:0003746;translation elongation factor activity;0.00450351263217758!GO:0000287;magnesium ion binding;0.00466782796884826!GO:0006891;intra-Golgi vesicle-mediated transport;0.00484993192303687!GO:0007243;protein kinase cascade;0.00485391129380668!GO:0032259;methylation;0.00488202827521517!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00488202827521517!GO:0015002;heme-copper terminal oxidase activity;0.00488202827521517!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00488202827521517!GO:0004129;cytochrome-c oxidase activity;0.00488202827521517!GO:0030176;integral to endoplasmic reticulum membrane;0.00488304913429057!GO:0031988;membrane-bound vesicle;0.00511114681253154!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0051207722097596!GO:0031970;organelle envelope lumen;0.00523937542126288!GO:0006611;protein export from nucleus;0.005277868941452!GO:0030518;steroid hormone receptor signaling pathway;0.00529124088605964!GO:0005876;spindle microtubule;0.00532971150153817!GO:0030118;clathrin coat;0.00533038293348349!GO:0008276;protein methyltransferase activity;0.00554624737102344!GO:0006505;GPI anchor metabolic process;0.00558984890197946!GO:0044431;Golgi apparatus part;0.00574187736476573!GO:0033116;ER-Golgi intermediate compartment membrane;0.00580775588780469!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00587128449635744!GO:0007040;lysosome organization and biogenesis;0.00598666868574531!GO:0005048;signal sequence binding;0.00606392592032156!GO:0016272;prefoldin complex;0.00637987387331848!GO:0047485;protein N-terminus binding;0.00647789814817014!GO:0030137;COPI-coated vesicle;0.00656467402919589!GO:0000096;sulfur amino acid metabolic process;0.00666855071918736!GO:0005774;vacuolar membrane;0.00670079470796222!GO:0006595;polyamine metabolic process;0.00688012564868615!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00703352579291528!GO:0006519;amino acid and derivative metabolic process;0.00722592707104708!GO:0008637;apoptotic mitochondrial changes;0.00722592707104708!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00722592707104708!GO:0045047;protein targeting to ER;0.00722592707104708!GO:0042770;DNA damage response, signal transduction;0.00733496469245176!GO:0031647;regulation of protein stability;0.00776340912983641!GO:0008312;7S RNA binding;0.00784431004608487!GO:0046822;regulation of nucleocytoplasmic transport;0.00799948026513865!GO:0030660;Golgi-associated vesicle membrane;0.0080229997786672!GO:0044454;nuclear chromosome part;0.00813124793591784!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00816168104119579!GO:0046966;thyroid hormone receptor binding;0.00818740972336529!GO:0006672;ceramide metabolic process;0.00827841907149047!GO:0000339;RNA cap binding;0.00830393157903285!GO:0031410;cytoplasmic vesicle;0.00834921691828395!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00851936091379102!GO:0004003;ATP-dependent DNA helicase activity;0.00879700283092061!GO:0043281;regulation of caspase activity;0.00904249846168584!GO:0016584;nucleosome positioning;0.00912602170291072!GO:0048487;beta-tubulin binding;0.00915739940090475!GO:0035258;steroid hormone receptor binding;0.00918646583163289!GO:0009124;nucleoside monophosphate biosynthetic process;0.00918646583163289!GO:0009123;nucleoside monophosphate metabolic process;0.00918646583163289!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00921987034260631!GO:0031902;late endosome membrane;0.00936407499352789!GO:0000152;nuclear ubiquitin ligase complex;0.00942457943161123!GO:0005869;dynactin complex;0.00946494186739447!GO:0009112;nucleobase metabolic process;0.00947881885692687!GO:0007041;lysosomal transport;0.00963808559729692!GO:0006355;regulation of transcription, DNA-dependent;0.00965716357995139!GO:0031123;RNA 3'-end processing;0.00993243858566779!GO:0016023;cytoplasmic membrane-bound vesicle;0.00996446405112813!GO:0008139;nuclear localization sequence binding;0.0102414331080041!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0104009746607722!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0104714053292965!GO:0010257;NADH dehydrogenase complex assembly;0.0104714053292965!GO:0033108;mitochondrial respiratory chain complex assembly;0.0104714053292965!GO:0030867;rough endoplasmic reticulum membrane;0.0105322924584243!GO:0043022;ribosome binding;0.0105411129810152!GO:0000781;chromosome, telomeric region;0.0105564995284164!GO:0046467;membrane lipid biosynthetic process;0.0106736888317251!GO:0016859;cis-trans isomerase activity;0.0107848012699476!GO:0043488;regulation of mRNA stability;0.0107932114890358!GO:0043487;regulation of RNA stability;0.0107932114890358!GO:0043596;nuclear replication fork;0.0107953633406979!GO:0007021;tubulin folding;0.0108363894204638!GO:0030041;actin filament polymerization;0.0108363894204638!GO:0030119;AP-type membrane coat adaptor complex;0.0109482753112133!GO:0031570;DNA integrity checkpoint;0.0109534385961064!GO:0000910;cytokinesis;0.0111782777815069!GO:0006376;mRNA splice site selection;0.0111782777815069!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0111782777815069!GO:0009615;response to virus;0.0114173761459524!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.0114947301447541!GO:0006497;protein amino acid lipidation;0.0116035848440958!GO:0051539;4 iron, 4 sulfur cluster binding;0.0116216140606856!GO:0007033;vacuole organization and biogenesis;0.0116337566800728!GO:0006406;mRNA export from nucleus;0.0120053806899423!GO:0030131;clathrin adaptor complex;0.012032472064464!GO:0050662;coenzyme binding;0.0125425724222371!GO:0000725;recombinational repair;0.0127644319290352!GO:0000724;double-strand break repair via homologous recombination;0.0127644319290352!GO:0019206;nucleoside kinase activity;0.0127708598408331!GO:0044437;vacuolar part;0.0129763048855072!GO:0007017;microtubule-based process;0.0130418905147037!GO:0006730;one-carbon compound metabolic process;0.0132312861663174!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.0137085166229922!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0138763313417719!GO:0000726;non-recombinational repair;0.0141835072900825!GO:0004576;oligosaccharyl transferase activity;0.0146512400547287!GO:0008652;amino acid biosynthetic process;0.0146710160665342!GO:0006270;DNA replication initiation;0.0146710160665342!GO:0008610;lipid biosynthetic process;0.0148111704502176!GO:0030521;androgen receptor signaling pathway;0.0148559850324609!GO:0015036;disulfide oxidoreductase activity;0.0149248583761061!GO:0016569;covalent chromatin modification;0.0150058530443973!GO:0008180;signalosome;0.0150058530443973!GO:0008629;induction of apoptosis by intracellular signals;0.0152294792466185!GO:0005832;chaperonin-containing T-complex;0.0153189765230963!GO:0006779;porphyrin biosynthetic process;0.0155610468433145!GO:0033014;tetrapyrrole biosynthetic process;0.0155610468433145!GO:0003887;DNA-directed DNA polymerase activity;0.0155907154895714!GO:0000209;protein polyubiquitination;0.0158121289401014!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0158701675523561!GO:0046519;sphingoid metabolic process;0.0159267794688265!GO:0000819;sister chromatid segregation;0.0159788360560302!GO:0009451;RNA modification;0.0162730556829619!GO:0009161;ribonucleoside monophosphate metabolic process;0.0165447055180468!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0165447055180468!GO:0008047;enzyme activator activity;0.0166089652503862!GO:0051287;NAD binding;0.0167557994327249!GO:0000178;exosome (RNase complex);0.0168001843936422!GO:0032561;guanyl ribonucleotide binding;0.0168001843936422!GO:0019001;guanyl nucleotide binding;0.0168001843936422!GO:0003702;RNA polymerase II transcription factor activity;0.016855238370135!GO:0006378;mRNA polyadenylation;0.0171543764496888!GO:0005874;microtubule;0.0171543764496888!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0172486997183059!GO:0008017;microtubule binding;0.0172699968992294!GO:0005765;lysosomal membrane;0.017408357125316!GO:0051540;metal cluster binding;0.0178215338637013!GO:0051536;iron-sulfur cluster binding;0.0178215338637013!GO:0000070;mitotic sister chromatid segregation;0.017855594196919!GO:0008213;protein amino acid alkylation;0.0180887664766889!GO:0006479;protein amino acid methylation;0.0180887664766889!GO:0006118;electron transport;0.0181237616821101!GO:0006220;pyrimidine nucleotide metabolic process;0.0181750565866606!GO:0004540;ribonuclease activity;0.0191692328423017!GO:0044438;microbody part;0.0195536908398977!GO:0044439;peroxisomal part;0.0195536908398977!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0200009639257827!GO:0000139;Golgi membrane;0.0202670409956681!GO:0006144;purine base metabolic process;0.0202723845374678!GO:0042158;lipoprotein biosynthetic process;0.0204766404009231!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0206014514277011!GO:0030134;ER to Golgi transport vesicle;0.0206014514277011!GO:0005996;monosaccharide metabolic process;0.0213746446677706!GO:0008022;protein C-terminus binding;0.0213773377681207!GO:0009127;purine nucleoside monophosphate biosynthetic process;0.0220466188453789!GO:0009167;purine ribonucleoside monophosphate metabolic process;0.0220466188453789!GO:0009126;purine nucleoside monophosphate metabolic process;0.0220466188453789!GO:0009168;purine ribonucleoside monophosphate biosynthetic process;0.0220466188453789!GO:0008234;cysteine-type peptidase activity;0.0221634391117624!GO:0009116;nucleoside metabolic process;0.0228270566295749!GO:0030508;thiol-disulfide exchange intermediate activity;0.0230851890433885!GO:0006509;membrane protein ectodomain proteolysis;0.0232163739369438!GO:0033619;membrane protein proteolysis;0.0232163739369438!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0233105161851805!GO:0008250;oligosaccharyl transferase complex;0.0234283557971302!GO:0030127;COPII vesicle coat;0.0235257217217103!GO:0012507;ER to Golgi transport vesicle membrane;0.0235257217217103!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0235688130085625!GO:0006807;nitrogen compound metabolic process;0.023751172556785!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0239349041658423!GO:0006733;oxidoreduction coenzyme metabolic process;0.0244273019908714!GO:0030522;intracellular receptor-mediated signaling pathway;0.0244350945477219!GO:0030132;clathrin coat of coated pit;0.0244828653192487!GO:0005652;nuclear lamina;0.0245465881051753!GO:0005777;peroxisome;0.0249999197571015!GO:0042579;microbody;0.0249999197571015!GO:0045947;negative regulation of translational initiation;0.0249999197571015!GO:0004532;exoribonuclease activity;0.0251620304741158!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.0251620304741158!GO:0019318;hexose metabolic process;0.0253763360959261!GO:0009967;positive regulation of signal transduction;0.0259587105165123!GO:0008320;protein transmembrane transporter activity;0.0262109789976868!GO:0031903;microbody membrane;0.0265922948166958!GO:0005778;peroxisomal membrane;0.0265922948166958!GO:0051090;regulation of transcription factor activity;0.0267790603739586!GO:0048471;perinuclear region of cytoplasm;0.0269083797055772!GO:0009308;amine metabolic process;0.0272514049751015!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0274100478503294!GO:0048518;positive regulation of biological process;0.0275618779944091!GO:0048037;cofactor binding;0.0280348061697192!GO:0022884;macromolecule transmembrane transporter activity;0.0287883382554822!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0287883382554822!GO:0000077;DNA damage checkpoint;0.0291004421105818!GO:0006767;water-soluble vitamin metabolic process;0.029325937087466!GO:0005669;transcription factor TFIID complex;0.0296075179847194!GO:0005784;translocon complex;0.0306970111835099!GO:0001836;release of cytochrome c from mitochondria;0.030827859882182!GO:0009303;rRNA transcription;0.0311936478389671!GO:0018196;peptidyl-asparagine modification;0.0320989346375911!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0320989346375911!GO:0004177;aminopeptidase activity;0.0321728920389417!GO:0043601;nuclear replisome;0.0327672772101433!GO:0030894;replisome;0.0327672772101433!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0329745665096105!GO:0030503;regulation of cell redox homeostasis;0.0340639882748196!GO:0016570;histone modification;0.0344093584895036!GO:0006516;glycoprotein catabolic process;0.034417854470957!GO:0016407;acetyltransferase activity;0.0349959958897417!GO:0009262;deoxyribonucleotide metabolic process;0.0350239438806443!GO:0031577;spindle checkpoint;0.0351037016394576!GO:0051098;regulation of binding;0.03551270124376!GO:0030911;TPR domain binding;0.0360423602042795!GO:0006783;heme biosynthetic process;0.0360434785329715!GO:0035267;NuA4 histone acetyltransferase complex;0.0362875009911021!GO:0008097;5S rRNA binding;0.0364740948282935!GO:0008538;proteasome activator activity;0.036514254654428!GO:0003725;double-stranded RNA binding;0.0367094258911473!GO:0005680;anaphase-promoting complex;0.0369137569027816!GO:0033367;protein localization in mast cell secretory granule;0.036937328713983!GO:0033365;protein localization in organelle;0.036937328713983!GO:0033371;T cell secretory granule organization and biogenesis;0.036937328713983!GO:0033373;maintenance of protease localization in mast cell secretory granule;0.036937328713983!GO:0033375;protease localization in T cell secretory granule;0.036937328713983!GO:0042629;mast cell granule;0.036937328713983!GO:0033377;maintenance of protein localization in T cell secretory granule;0.036937328713983!GO:0033364;mast cell secretory granule organization and biogenesis;0.036937328713983!GO:0033380;granzyme B localization in T cell secretory granule;0.036937328713983!GO:0033379;maintenance of protease localization in T cell secretory granule;0.036937328713983!GO:0033370;maintenance of protein localization in mast cell secretory granule;0.036937328713983!GO:0033368;protease localization in mast cell secretory granule;0.036937328713983!GO:0033366;protein localization in secretory granule;0.036937328713983!GO:0033382;maintenance of granzyme B localization in T cell secretory granule;0.036937328713983!GO:0033374;protein localization in T cell secretory granule;0.036937328713983!GO:0004748;ribonucleoside-diphosphate reductase activity;0.0371328388664451!GO:0016728;oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor;0.0371328388664451!GO:0006596;polyamine biosynthetic process;0.037204347499927!GO:0000097;sulfur amino acid biosynthetic process;0.037254466226212!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.037282292164861!GO:0007004;telomere maintenance via telomerase;0.0373555234787191!GO:0006007;glucose catabolic process;0.0373555234787191!GO:0031371;ubiquitin conjugating enzyme complex;0.0375841257916797!GO:0030433;ER-associated protein catabolic process;0.0375861602541966!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0375861602541966!GO:0031252;leading edge;0.0379461703731892!GO:0006643;membrane lipid metabolic process;0.0383957483850736!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0387228630411463!GO:0045039;protein import into mitochondrial inner membrane;0.0387228630411463!GO:0045936;negative regulation of phosphate metabolic process;0.0387305952873292!GO:0051336;regulation of hydrolase activity;0.0388564694054371!GO:0006740;NADPH regeneration;0.0389247170497346!GO:0006098;pentose-phosphate shunt;0.0389247170497346!GO:0006919;caspase activation;0.0389710061746267!GO:0000790;nuclear chromatin;0.0389710061746267!GO:0022415;viral reproductive process;0.0389949678305247!GO:0008536;Ran GTPase binding;0.0394086721865623!GO:0004448;isocitrate dehydrogenase activity;0.0402121021043719!GO:0043189;H4/H2A histone acetyltransferase complex;0.0402794363851237!GO:0006778;porphyrin metabolic process;0.0403009884061205!GO:0033013;tetrapyrrole metabolic process;0.0403009884061205!GO:0042826;histone deacetylase binding;0.041086067821753!GO:0005975;carbohydrate metabolic process;0.0410997988533502!GO:0051053;negative regulation of DNA metabolic process;0.0430259832103602!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0438253871637866!GO:0045815;positive regulation of gene expression, epigenetic;0.0438348552817145!GO:0033558;protein deacetylase activity;0.0439196551750336!GO:0006367;transcription initiation from RNA polymerase II promoter;0.0444021051482169!GO:0008408;3'-5' exonuclease activity;0.0451458345839006!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0454151345852212!GO:0051223;regulation of protein transport;0.0458986818124022!GO:0007162;negative regulation of cell adhesion;0.045910778117864!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0461483754654355!GO:0009081;branched chain family amino acid metabolic process;0.0473511508289415!GO:0006266;DNA ligation;0.0478257277009723!GO:0006635;fatty acid beta-oxidation;0.0481775030463206!GO:0044450;microtubule organizing center part;0.0484278222298193!GO:0032603;fractalkine production;0.0484278222298193!GO:0050725;positive regulation of interleukin-1 beta biosynthetic process;0.0484278222298193!GO:0050752;regulation of fractalkine biosynthetic process;0.0484278222298193!GO:0045362;positive regulation of interleukin-1 biosynthetic process;0.0484278222298193!GO:0050754;positive regulation of fractalkine biosynthetic process;0.0484278222298193!GO:0001774;microglial cell activation;0.0484278222298193!GO:0050756;fractalkine metabolic process;0.0484278222298193!GO:0005766;primary lysosome;0.0484278222298193!GO:0050751;fractalkine biosynthetic process;0.0484278222298193!GO:0042222;interleukin-1 biosynthetic process;0.0484278222298193!GO:0050722;regulation of interleukin-1 beta biosynthetic process;0.0484278222298193!GO:0045360;regulation of interleukin-1 biosynthetic process;0.0484278222298193!GO:0042582;azurophil granule;0.0484278222298193!GO:0050720;interleukin-1 beta biosynthetic process;0.0484278222298193!GO:0045792;negative regulation of cell size;0.0484278222298193!GO:0016311;dephosphorylation;0.0489368099681338!GO:0051338;regulation of transferase activity;0.0489803891218036!GO:0030125;clathrin vesicle coat;0.0494181338897069!GO:0030665;clathrin coated vesicle membrane;0.0494181338897069 | |||
|sample_id=10718 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=MYB:1.98949508227;STAT1,3:1.27776386723;CRX:1.22869748063;POU2F1..3:1.22608894054;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.15227843081;PITX1..3:1.12037508521;FOXP1:1.11371342288;POU1F1:1.08429089615;E2F1..5:1.0554771636;ALX1:0.954778650058;ELK1,4_GABP{A,B1}:0.950126738496;YY1:0.92847359344;FOXQ1:0.919622868859;NKX2-2,8:0.896447433303;ELF1,2,4:0.888964172684;AIRE:0.886762210752;DMAP1_NCOR{1,2}_SMARC:0.880410750649;SPIB:0.85377185358;NANOG:0.7907229304;NR5A1,2:0.788272860305;ZNF143:0.78300569974;FOXL1:0.746049727214;NFY{A,B,C}:0.74110427542;HOX{A6,A7,B6,B7}:0.732952337077;TOPORS:0.724369608701;SPI1:0.706445410869;RFX2..5_RFXANK_RFXAP:0.640895497051;CDX1,2,4:0.616132560171;HBP1_HMGB_SSRP1_UBTF:0.596435209362;ZBTB16:0.589463655347;RUNX1..3:0.563654695805;POU5F1:0.525872032915;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.49961591271;PAX8:0.468892207378;OCT4_SOX2{dimer}:0.45094753933;CEBPA,B_DDIT3:0.441939709975;NANOG{mouse}:0.408064459691;GATA6:0.402012217903;MTF1:0.393739764066;TEF:0.37844157181;ETS1,2:0.360455988503;NR6A1:0.319330161443;PPARG:0.313683137234;BREu{core}:0.308784321179;NRF1:0.284264217093;GFI1:0.281604167952;CUX2:0.280586974335;VSX1,2:0.279748341559;ARID5B:0.26670409867;NKX3-1:0.225924084749;AHR_ARNT_ARNT2:0.199191063362;ZNF238:0.198438321968;NFIL3:0.142284772761;PRRX1,2:0.118337699145;TLX2:0.117265821573;STAT5{A,B}:0.108230316611;ONECUT1,2:0.0999020619204;FOXP3:0.0811385248237;SOX{8,9,10}:0.060163552089;NKX2-3_NKX2-5:0.0576024307163;PAX5:0.0416398714874;FOXA2:0.0372002702708;DBP:0.0237673035017;RFX1:0.023607180594;CREB1:0.0221348412297;PAX4:0.0138033498674;FOX{F1,F2,J1}:-0.0158317218109;HOX{A4,D4}:-0.0237813148321;TAL1_TCF{3,4,12}:-0.0551528287744;RXR{A,B,G}:-0.0651955938383;GCM1,2:-0.0927435995662;HAND1,2:-0.108766258842;PBX1:-0.121473469587;GTF2A1,2:-0.149076661678;HNF1A:-0.152020787575;REST:-0.164727704921;IRF1,2:-0.179306153137;IKZF2:-0.193668645403;MYOD1:-0.199311176113;ZNF384:-0.216543790985;EVI1:-0.216942564288;HNF4A_NR2F1,2:-0.235491577082;RORA:-0.236882159027;RXRA_VDR{dimer}:-0.238095309511;EP300:-0.245243916791;NKX6-1,2:-0.24726684646;TFDP1:-0.260800037342;ATF5_CREB3:-0.267438845294;SOX17:-0.282147260618;MEF2{A,B,C,D}:-0.287659188153;TP53:-0.316114680901;BPTF:-0.327941970828;HLF:-0.328662230821;NFKB1_REL_RELA:-0.337618796661;POU3F1..4:-0.340928397999;SREBF1,2:-0.348881080693;EN1,2:-0.351815913688;FOX{I1,J2}:-0.357596082193;TGIF1:-0.357610946432;SOX5:-0.370790946155;PAX3,7:-0.375949175699;HMGA1,2:-0.384516824801;NKX3-2:-0.387358311602;ATF4:-0.403884692529;AR:-0.413524403008;RBPJ:-0.413729879436;CDC5L:-0.422378170644;ESR1:-0.426266427482;IKZF1:-0.432650664225;FOXD3:-0.437510777705;KLF4:-0.438407319333;ZEB1:-0.44664409178;NFE2:-0.449096750801;MYBL2:-0.449105839304;PRDM1:-0.459336713555;XBP1:-0.460138347911;PAX2:-0.473496757013;HIF1A:-0.485932852981;HES1:-0.497845753362;NR1H4:-0.501889478842;ATF2:-0.507101653885;FOS_FOS{B,L1}_JUN{B,D}:-0.508512706933;bHLH_family:-0.52480503625;UFEwm:-0.563935992833;NFIX:-0.570784013037;FOXM1:-0.571213975973;POU6F1:-0.576680776345;NFE2L2:-0.591844084325;BACH2:-0.5922629898;XCPE1{core}:-0.593669765298;T:-0.601997143949;ZNF148:-0.602645465436;PAX6:-0.6029939178;IRF7:-0.606728091318;HOX{A5,B5}:-0.615991448933;LMO2:-0.622514674275;LHX3,4:-0.624097657021;FOSL2:-0.641519808388;STAT2,4,6:-0.651724988671;GATA4:-0.656420139964;FOXN1:-0.677009866215;ESRRA:-0.688326400195;NFE2L1:-0.707450774897;MYFfamily:-0.708421272027;ZFP161:-0.721153796266;NHLH1,2:-0.735012141247;TBP:-0.736029131421;SRF:-0.755051514456;ADNP_IRX_SIX_ZHX:-0.781991471157;SNAI1..3:-0.830002324196;FOX{D1,D2}:-0.856574755044;TFAP4:-0.86310877244;ZNF423:-0.875310616463;TFAP2{A,C}:-0.902188579327;FOXO1,3,4:-0.924414984852;MZF1:-0.94443227171;TFAP2B:-0.978697844837;SP1:-0.981637808506;HOXA9_MEIS1:-0.983977881325;GFI1B:-0.99610126303;HMX1:-1.0245482425;GTF2I:-1.03298924678;MED-1{core}:-1.11347342173;NKX2-1,4:-1.12136764587;LEF1_TCF7_TCF7L1,2:-1.14334909623;ZIC1..3:-1.1456034518;RREB1:-1.16845594874;GLI1..3:-1.18235434618;MAFB:-1.23495099939;TFCP2:-1.29344181685;ZBTB6:-1.29973568417;TEAD1:-1.31249300837;SPZ1:-1.32738231323;JUN:-1.33060909762;SMAD1..7,9:-1.33177292764;EGR1..3:-1.35152698826;HSF1,2:-1.37158796535;HIC1:-1.3849033191;ATF6:-1.40519202675;TLX1..3_NFIC{dimer}:-1.41441961817;PATZ1:-1.41615927537;MTE{core}:-1.43354452978;GZF1:-1.49553298855;NR3C1:-1.57628162206;MAZ:-1.57962262421;PAX1,9:-1.59637831554;SOX2:-1.64981969451;EBF1:-1.74174451329;NFATC1..3:-1.74825298665;ALX4:-1.76439839125;TBX4,5:-1.90382369053;PDX1:-1.91846663939 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10718-109I7;search_select_hide=table117:FF:10718-109I7 | |||
}} | }} |
Latest revision as of 15:01, 3 June 2020
Name: | biphenotypic B myelomonocytic leukemia cell line:MV-4-11 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11845 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11845
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11845
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.02 |
10 | 10 | 0.012 |
100 | 100 | 0.133 |
101 | 101 | 0.179 |
102 | 102 | 0.522 |
103 | 103 | 0.754 |
104 | 104 | 0.965 |
105 | 105 | 0.828 |
106 | 106 | 0.887 |
107 | 107 | 0.263 |
108 | 108 | 0.779 |
109 | 109 | 0.064 |
11 | 11 | 0.0333 |
110 | 110 | 0.18 |
111 | 111 | 0.172 |
112 | 112 | 0.98 |
113 | 113 | 0.989 |
114 | 114 | 0.0856 |
115 | 115 | 0.718 |
116 | 116 | 0.256 |
117 | 117 | 0.0258 |
118 | 118 | 0.169 |
119 | 119 | 0.234 |
12 | 12 | 0.448 |
120 | 120 | 0.643 |
121 | 121 | 0.291 |
122 | 122 | 0.93 |
123 | 123 | 2.26851e-5 |
124 | 124 | 0.045 |
125 | 125 | 0.478 |
126 | 126 | 0.221 |
127 | 127 | 0.195 |
128 | 128 | 0.555 |
129 | 129 | 0.282 |
13 | 13 | 0.0036 |
130 | 130 | 0.743 |
131 | 131 | 0.132 |
132 | 132 | 0.799 |
133 | 133 | 0.823 |
134 | 134 | 0.221 |
135 | 135 | 0.268 |
136 | 136 | 0.251 |
137 | 137 | 0.569 |
138 | 138 | 0.762 |
139 | 139 | 0.206 |
14 | 14 | 0.94 |
140 | 140 | 0.614 |
141 | 141 | 0.526 |
142 | 142 | 0.348 |
143 | 143 | 0.791 |
144 | 144 | 0.993 |
145 | 145 | 0.416 |
146 | 146 | 0.727 |
147 | 147 | 0.364 |
148 | 148 | 0.168 |
149 | 149 | 0.813 |
15 | 15 | 0.527 |
150 | 150 | 0.606 |
151 | 151 | 0.838 |
152 | 152 | 0.376 |
153 | 153 | 0.912 |
154 | 154 | 0.869 |
155 | 155 | 0.0125 |
156 | 156 | 0.685 |
157 | 157 | 0.38 |
158 | 158 | 0.487 |
159 | 159 | 0.138 |
16 | 16 | 0.977 |
160 | 160 | 0.616 |
161 | 161 | 0.249 |
162 | 162 | 0.938 |
163 | 163 | 0.244 |
164 | 164 | 0.201 |
165 | 165 | 0.108 |
166 | 166 | 0.296 |
167 | 167 | 0.0269 |
168 | 168 | 0.316 |
169 | 169 | 0.111 |
17 | 17 | 0.67 |
18 | 18 | 0.967 |
19 | 19 | 0.554 |
2 | 2 | 0.369 |
20 | 20 | 0.281 |
21 | 21 | 0.0865 |
22 | 22 | 0.591 |
23 | 23 | 0.0777 |
24 | 24 | 0.399 |
25 | 25 | 0.227 |
26 | 26 | 0.0143 |
27 | 27 | 0.577 |
28 | 28 | 0.822 |
29 | 29 | 0.0193 |
3 | 3 | 0.0413 |
30 | 30 | 0.0446 |
31 | 31 | 0.553 |
32 | 32 | 0.451 |
33 | 33 | 0.421 |
34 | 34 | 0.984 |
35 | 35 | 0.343 |
36 | 36 | 0.00621 |
37 | 37 | 0.153 |
38 | 38 | 0.213 |
39 | 39 | 0.466 |
4 | 4 | 0.222 |
40 | 40 | 0.106 |
41 | 41 | 0.664 |
42 | 42 | 0.162 |
43 | 43 | 0.534 |
44 | 44 | 0.328 |
45 | 45 | 0.517 |
46 | 46 | 0.106 |
47 | 47 | 0.0144 |
48 | 48 | 0.0165 |
49 | 49 | 0.192 |
5 | 5 | 0.712 |
50 | 50 | 0.877 |
51 | 51 | 0.657 |
52 | 52 | 0.483 |
53 | 53 | 0.149 |
54 | 54 | 0.964 |
55 | 55 | 0.737 |
56 | 56 | 0.984 |
57 | 57 | 0.217 |
58 | 58 | 0.192 |
59 | 59 | 0.598 |
6 | 6 | 0.391 |
60 | 60 | 0.616 |
61 | 61 | 0.173 |
62 | 62 | 0.197 |
63 | 63 | 0.548 |
64 | 64 | 0.0885 |
65 | 65 | 0.732 |
66 | 66 | 0.0901 |
67 | 67 | 0.983 |
68 | 68 | 0.5 |
69 | 69 | 0.102 |
7 | 7 | 0.142 |
70 | 70 | 0.957 |
71 | 71 | 0.0369 |
72 | 72 | 0.867 |
73 | 73 | 0.185 |
74 | 74 | 0.933 |
75 | 75 | 0.0158 |
76 | 76 | 0.104 |
77 | 77 | 0.785 |
78 | 78 | 0.0696 |
79 | 79 | 0.35 |
8 | 8 | 0.0852 |
80 | 80 | 0.139 |
81 | 81 | 0.304 |
82 | 82 | 0.817 |
83 | 83 | 0.853 |
84 | 84 | 0.394 |
85 | 85 | 0.919 |
86 | 86 | 0.773 |
87 | 87 | 0.0941 |
88 | 88 | 0.681 |
89 | 89 | 0.212 |
9 | 9 | 0.698 |
90 | 90 | 0.0181 |
91 | 91 | 0.691 |
92 | 92 | 0.369 |
93 | 93 | 0.822 |
94 | 94 | 0.523 |
95 | 95 | 0.0246 |
96 | 96 | 0.655 |
97 | 97 | 0.391 |
98 | 98 | 0.337 |
99 | 99 | 0.523 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11845
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0100740 myeloid leukemia cell line sample
FF:0100741 lymphocytic leukemia cell line sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100741 (lymphocytic leukemia cell line sample)
0100740 (myeloid leukemia cell line sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)