FF:10752-110D5: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00004745 | ||
| | |DRA_sample_Accession_RNASeq=RNA-Seq@SAMD00004745 | ||
| | |accession_numbers=CAGE;DRX007919;DRR008791;DRZ000216;DRZ001601;DRZ011566;DRZ012951 | ||
| | |accession_numbers_RNASeq=RNA-Seq;DRX057138;DRR062897;DRZ007973 | ||
| | |ancestors_in_anatomy_facet= | ||
| | |ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000988,CL:0000548,CL:0000763,CL:0002371,CL:0000255 | ||
| | |ancestors_in_disease_facet=DOID:4,DOID:0050686,DOID:162,DOID:2531,DOID:14566,DOID:0060083,DOID:1240,DOID:1036,DOID:8692 | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0100737,FF:0102580,FF:0101035,FF:0100740,FF:0102581 | ||
|comment= | |||
|created_by= | |||
| | |creation_date= | ||
| | |data_phase=2 | ||
| | |datafreeze_phase=2 | ||
| | |def= | ||
| | |expression_enrichment_score=chr12:54694758..54694805,-!p1@NFE2!2.21!193.25!NFE2;;chr3:128212033..128212051,-!p1@GATA2!2.17!146.12!GATA2;;chrX:48644984..48645005,+!p1@GATA1!2.10!123.88!GATA1;;chr12:54694807..54694832,-!p3@NFE2!1.97!91.45!NFE2;;chr6:135502501..135502546,+!p1@MYB!1.92!96.87!MYB;;chr19:13213511..13213545,-!p2@LYL1!1.81!68.88!LYL1;;chr9:135854091..135854159,+!p1@GFI1B!1.80!62.80!GFI1B;;chr5:134369905..134369972,-!p1@PITX1!1.72!78.40!PITX1;;chr1:47695003..47695042,-!p2@TAL1!1.72!50.98!TAL1;;chr19:12998003..12998021,-!p1@KLF1!1.71!50.82!KLF1;;chrY:21906594..21906622,-!p1@KDM5D!1.57!36.20!KDM5D;;chr21:39870339..39870443,-!p1@ERG!1.54!33.99!ERG;;chr6:135502408..135502459,+!p2@MYB!1.51!36.12!MYB;;chr9:20382446..20382493,-!p4@MLLT3!1.49!30.13!MLLT3;;chr11:47400078..47400106,-!p1@SPI1!1.45!27.17!SPI1;;chr3:128206762..128206781,-!p2@GATA2!1.41!149.00!GATA2;;chr5:134369879..134369898,-!p2@PITX1!1.39!23.31!PITX1;;chr1:47903709..47903764,+!p1@BC169308!1.36!25.04!FOXD2;;chr17:46622229..46622257,-!p6@HOXB2!1.31!22.90!HOXB2;;chr15:96869511..96869525,+!p16@NR2F2!1.30!21.18!NR2F2;;chr10:94449703..94449718,+!p1@HHEX!1.29!70.19!HHEX;;chr1:47697881..47697910,-!p4@TAL1!1.23!16.17!TAL1;;chr19:13213555..13213568,-!p5@LYL1!1.23!15.93!LYL1;;chr6:135502472..135502489,+!p3@MYB!1.22!15.52!MYB;;chr2:239148671..239148686,-!p1@HES6!1.19!52.46!HES6;;chr11:47400045..47400060,-!p6@SPI1!1.19!14.53!SPI1;;chr2:187350973..187351072,+!p1@ZC3H15!1.17!1179.67!ZC3H15;;chr12:54694653..54694672,-!p2@NFE2!1.17!13.79!NFE2;;chr7:27205106..27205134,-!p2@HOXA9!1.17!13.79!HOXA9;;chr12:54689532..54689551,-!p4@NFE2!1.16!13.55!NFE2;;chr5:88178983..88179012,-!p1@MEF2C!1.15!99.99!MEF2C;;chr18:22932080..22932170,-!p1@ZNF521!1.13!53.28!ZNF521;;chr11:120107344..120107351,+!p1@POU2F3!1.13!15.27!POU2F3;;chr11:47399996..47400014,-!p4@SPI1!1.13!12.56!SPI1;;chr6:15401104..15401166,+!p5@JARID2!1.11!11.82!JARID2;;chr17:46622205..46622218,-!p3@HOXB2!1.10!13.38!HOXB2;;chr11:47399947..47399961,-!p3@SPI1!1.09!11.41!SPI1;;chr11:47400032..47400043,-!p5@SPI1!1.09!11.33!SPI1;;chr8:128748308..128748324,+!p2@MYC!1.07!299.64!MYC;;chrY:2803415..2803468,+!p1@ZFY!1.07!10.84!ZFY;;chr15:76629123..76629151,+!p1@ISL2!1.06!11.74!ISL2;;chr8:28748099..28748141,+!p2@HMBOX1!1.04!31.61!HMBOX1;;chr17:40441354..40441410,+!p2@STAT5A!1.04!9.85!STAT5A;;chr21:36421535..36421610,-!p2@RUNX1!1.03!35.46!RUNX1;;chr10:94449675..94449694,+!p2@HHEX!1.03!26.19!HHEX;;chrX:48644976..48644983,+!p2@GATA1!1.03!9.69!GATA1;;chr2:157189180..157189290,-!p1@NR4A2!1.02!50.82!NR4A2;;chr15:96876966..96877017,+!p12@NR2F2!1.02!13.87!NR2F2;;chr2:187350951..187350962,+!p2@ZC3H15!1.01!22.16!ZC3H15;;chr7:115670804..115670825,-!p1@TFEC!1.01!9.19!TFEC;;chr11:65687362..65687436,+!p3@DRAP1!1.00!41.79!DRAP1;;chr19:52074502..52074587,+!p1@ZNF175!0.98!31.85!ZNF175;;chr3:24536253..24536328,-!p1@THRB!0.97!16.17!THRB;;chr12:54694738..54694749,-!p5@NFE2!0.97!8.29!NFE2;;chr15:60296442..60296464,+!p1@FOXB1!0.97!8.29!FOXB1;;chr6:20402102..20402152,+!p1@E2F3!0.96!34.48!E2F3;;chr11:32457075..32457095,-!p1@WT1!0.94!7.80!WT1;;chr17:46622440..46622477,-!p5@HOXB2!0.92!8.29!HOXB2;;chr7:27205136..27205164,-!p1@HOXA9!0.92!7.39!HOXA9;;chr7:35293685..35293718,-!p1@TBX20!0.92!7.39!TBX20;;chrX:48645010..48645015,+!p3@GATA1!0.92!7.22!GATA1;;chr9:135854074..135854089,+!p2@GFI1B!0.92!7.22!GFI1B;;chr1:47691303..47691319,-!p5@TAL1!0.92!7.22!TAL1;;chr6:126240380..126240430,+!p2@NCOA7!0.91!19.21!NCOA7;;chr19:12203100..12203132,+!p1@ZNF788!0.91!14.78!ZNF788;;chr19:22235279..22235301,+!p1@ZNF257!0.91!13.79!ZNF257;;chr17:46703687..46703740,-!p1@HOXB9!0.90!6.98!HOXB9;;chr1:47903765..47903783,+!p3@BC169308!0.90!6.90!FOXD2;;chr2:145277640..145277771,-!p1@ZEB2!0.89!95.06!ZEB2;;chr15:96874012..96874042,+!p2@NR2F2!0.89!63.38!NR2F2;;chr12:54785074..54785122,-!p2@ZNF385A!0.89!10.59!ZNF385A;;chr5:88179195..88179224,-!p3@MEF2C!0.88!10.84!MEF2C;;chr17:42295777..42295816,-!p7@UBTF!0.88!8.13!UBTF;;chr17:7492684..7492778,-!p2@SOX15!0.87!14.12!SOX15;;chr1:47697539..47697573,-!p3@TAL1!0.87!6.49!TAL1;;chr17:40440481..40440550,+!p1@STAT5A!0.86!47.78!STAT5A;;chr4:4291837..4291859,-!p2@LYAR!0.86!21.67!LYAR;;chr1:61548069..61548102,+!p3@NFIA!0.86!15.76!NFIA;;chr11:615570..615721,-!p2@IRF7!0.86!12.72!IRF7;;chr17:46655704..46655718,-!p2@HOXB4!0.85!9.36!HOXB4;;chr6:134274354..134274371,+!p1@TBPL1!0.84!166.07!TBPL1;;chr16:29819446..29819471,+!p9@MAZ!0.84!18.64!MAZ;;chr19:19281060..19281078,-!p2@MEF2BNB-MEF2B,p2@MEF2B!0.84!5.91!MEF2B;;chr19:45971246..45971265,+!p1@FOSB!0.83!115.18!FOSB;;chr8:10588010..10588030,-!p1@SOX7!0.82!5.66!SOX7;;chr17:38020392..38020477,-!p1@IKZF3!0.82!5.58!IKZF3;;chr21:36260980..36261011,-!p1@RUNX1!0.81!171.74!RUNX1;;chr5:88179017..88179046,-!p2@MEF2C!0.80!22.90!MEF2C;;chr19:54058073..54058088,+!p1@ZNF331!0.80!5.25!ZNF331;;chr1:92949331..92949377,-!p2@GFI1!0.80!5.25!GFI1;;chr19:13213465..13213478,-!p7@LYL1!0.80!5.25!LYL1;;chr19:54024251..54024305,+!p4@ZNF331!0.78!8.46!ZNF331;;chr8:102216978..102217003,-!p4@ZNF706!0.78!5.09!ZNF706;;chr17:46655578..46655589,-!p4@HOXB4!0.77!4.84!HOXB4;;chr19:20188776..20188826,+!p1@ZNF90!0.76!13.87!ZNF90;;chr8:124286495..124286548,-!p1@ZHX1!0.75!49.75!ZHX1;;chr1:47779762..47779827,-!p1@STIL,p1@TAL1!0.75!23.23!TAL1;;chr18:77155922..77155939,+!p1@NFATC1!0.75!13.79!NFATC1;;chr18:22932004..22932021,-!p2@ZNF521!0.75!4.68!ZNF521;;chr11:47400062..47400077,-!p2@SPI1!0.75!4.68!SPI1;;chr17:40440446..40440464,+!p5@STAT5A!0.75!4.60!STAT5A;;chr17:42295682..42295731,-!p17@UBTF!0.75!4.60!UBTF;;chr19:58545454..58545498,+!p1@ZSCAN1!0.75!4.60!ZSCAN1;;chr19:9695169..9695188,-!p1@ZNF121!0.74!89.23!ZNF121;;chrX:84499081..84499115,+!p2@ZNF711!0.74!6.98!ZNF711;;chr19:13213662..13213686,-!p1@LYL1!0.74!6.90!LYL1;;chr8:28748157..28748175,+!p3@HMBOX1!0.74!5.58!HMBOX1;;chr19:54024313..54024361,+!p7@ZNF331!0.74!4.52!ZNF331;;chr17:46655672..46655697,-!p3@HOXB4!0.74!4.52!HOXB4;;chrY:21906761..21906810,-!p2@KDM5D!0.74!4.52!KDM5D;;chr17:46622175..46622186,-!p12@HOXB2!0.74!4.43!HOXB2;;chr15:96873921..96873946,+!p1@NR2F2!0.73!138.82!NR2F2;;chr19:23433144..23433204,-!p1@ZNF724P!0.73!21.92!ZNF724P;;chr1:158985493..158985535,+!p4@IFI16!0.73!7.06!IFI16;;chr16:29819403..29819442,+!p5@MAZ!0.72!38.99!MAZ;;chr17:46621146..46621180,-!p10@HOXB2!0.72!4.27!HOXB2;;chr2:8822176..8822196,+!p1@ID2!0.71!662.49!ID2;;chr3:141747459..141747475,-!p1@TFDP2!0.71!38.67!TFDP2;;chr8:145159447..145159458,+!p4@MAF1!0.71!10.67!MAF1;;chr18:3448455..3448480,+!p5@TGIF1!0.71!8.21!TGIF1;;chr2:185463247..185463263,+!p1@ZNF804A!0.71!7.80!ZNF804A;;chr6:100061724..100061753,+!p1@PRDM13!0.71!4.19!PRDM13;;chr1:47695156..47695179,-!p10@TAL1!0.71!4.19!TAL1;;chr19:21950332..21950356,-!p2@ZNF100!0.70!9.19!ZNF100;;chr8:37963466..37963506,+!p3@ASH2L!0.70!5.25!ASH2L;;chr8:144373550..144373617,+!p1@ZNF696!0.69!15.68!ZNF696;;chr1:43148855..43148908,+!p4@YBX1!0.69!6.49!YBX1;;chr1:47696918..47696935,-!p6@TAL1!0.69!3.94!TAL1;;chr1:92951607..92951661,-!p1@GFI1!0.69!3.94!GFI1;;chr2:60780607..60780624,-!p2@BCL11A!0.68!12.81!BCL11A;;chr15:96875657..96875760,+!p14@NR2F2!0.68!6.73!NR2F2;;chr17:40440177..40440190,+!p6@STAT5A!0.68!3.78!STAT5A;;chr11:32457103..32457123,-!p3@WT1!0.68!3.78!WT1;;chr9:135854058..135854072,+!p3@GFI1B!0.68!3.78!GFI1B;;chr6:135513595..135513617,+!p4@MYB!0.67!3.69!MYB;;chr12:54778471..54778528,-!p1@ZNF385A!0.67!3.69!ZNF385A;;chr8:128748470..128748487,+!p1@MYC!0.66!464.64!MYC;;chr6:126102292..126102329,+!p3@NCOA7!0.66!13.38!NCOA7;;chr1:61547894..61547968,+!p2@NFIA!0.66!11.82!NFIA;;chr6:126102254..126102289,+!p5@NCOA7!0.66!11.16!NCOA7;;chr3:18486354..18486377,-!p2@SATB1!0.66!4.68!SATB1;;chr2:172949484..172949522,+!p1@DLX1!0.66!3.61!DLX1;;chr5:134369973..134369984,-!p3@PITX1!0.66!3.61!PITX1;;chr7:50348268..50348366,+!p4@IKZF1!0.66!3.61!IKZF1;;chr12:54689552..54689574,-!p6@NFE2!0.66!3.61!NFE2;;chr7:50344289..50344323,+!p1@IKZF1!0.66!3.53!IKZF1;;chr11:615942..615957,-!p1@IRF7!0.65!38.42!IRF7;;chr20:48599506..48599526,+!p1@SNAI1!0.65!26.11!SNAI1;;chr20:42295713..42295738,+!p2@MYBL2!0.65!23.56!MYBL2;;chrX:129244840..129244881,-!p2@ELF4!0.65!15.27!ELF4;;chr20:31350184..31350200,+!p1@DNMT3B!0.65!7.96!DNMT3B;;chr1:25256756..25256774,-!p1@RUNX3!0.65!7.06!RUNX3;;chr11:65688056..65688069,+!p21@DRAP1!0.65!3.45!DRAP1;;chr7:50343634..50343717,+!p2@IKZF1!0.65!3.45!IKZF1;;chr13:41593425..41593480,-!p1@ELF1!0.64!24.71!ELF1;;chr19:24097706..24097731,+!p2@ZNF726!0.64!7.14!ZNF726;;chr19:23299814..23299844,+!p1@ZNF730!0.64!4.27!ZNF730;;chr6:126240356..126240379,+!p7@NCOA7!0.64!4.27!NCOA7;;chr4:109089901..109089930,-!p3@LEF1!0.64!3.37!LEF1;;chr12:11802753..11802834,+!p2@ETV6!0.63!18.47!ETV6;;chr2:231084639..231084654,-!p2@SP110!0.63!5.91!SP110;;chr8:128747757..128747800,+!p7@MYC!0.63!4.68!MYC;;chr19:58740449..58740456,+!p3@ZNF544!0.63!3.28!ZNF544;;chr11:65667884..65667895,-!p2@FOSL1!0.62!14.45!FOSL1;;chr19:11959532..11959593,+!p1@ZNF439!0.62!14.04!ZNF439;;chr1:249132462..249132481,+!p6@ZNF672!0.62!5.75!ZNF672;;chr17:41623009..41623053,-!p4@ETV4!0.62!5.50!ETV4;;chr12:54785054..54785072,-!p4@ZNF385A!0.62!3.69!ZNF385A;;chr16:29819558..29819572,+!p28@MAZ!0.62!3.20!MAZ;;chr1:67395982..67396015,+!p4@MIER1!0.61!9.36!MIER1;;chr17:46655730..46655791,-!p1@HOXB4!0.61!8.70!HOXB4;;chr1:45805872..45805900,+!p2@TOE1!0.61!8.46!TOE1;;chr15:96874244..96874259,+!p5@NR2F2!0.61!8.37!NR2F2;;chr8:128747661..128747703,+!p6@MYC!0.61!4.35!MYC;;chr17:46675420..46675465,-!p3@HOXB6!0.61!3.69!HOXB6;;chr19:13213496..13213501,-!p10@LYL1!0.61!3.12!LYL1;;chr20:22564895..22564910,-!p1@FOXA2!0.61!3.12!FOXA2;;chr20:22565185..22565223,-!p3@FOXA2!0.61!3.12!FOXA2;;chr14:37131058..37131139,+!p1@PAX9!0.61!3.12!PAX9;;chr3:128207349..128207386,-!p3@GATA2!0.61!3.12!GATA2;;chr15:67391010..67391046,+!p13@SMAD3!0.61!3.04!SMAD3;;chr19:13213399..13213414,-!p6@LYL1!0.61!3.04!LYL1;;chr19:36706055..36706074,+!p3@ZNF146!0.60!16.34!ZNF146;;chr16:68119324..68119364,+!p1@NFATC3!0.60!15.93!NFATC3;;chr1:43148792..43148849,+!p2@YBX1!0.60!13.38!YBX1;;chr18:53254566..53254567,-!p8@TCF4!0.60!5.42!TCF4;;chr17:46622114..46622138,-!p4@HOXB2!0.60!4.93!HOXB2;;chr8:80679993..8068001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| ||
| | |ffid_belonging_in_development=CL:0000049,CL:0000134 | ||
| | |||
|fonse_cell_line=FF:0101035 | |fonse_cell_line=FF:0101035 | ||
|fonse_cell_line_closure=FF:0101035 | |fonse_cell_line_closure=FF:0101035 | ||
Line 66: | Line 42: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/leukemia%252c%2520chronic%2520megakaryoblastic%2520cell%2520line%253aMEG-01.CNhs11859.10752-110D5.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/leukemia%252c%2520chronic%2520megakaryoblastic%2520cell%2520line%253aMEG-01.CNhs11859.10752-110D5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/leukemia%252c%2520chronic%2520megakaryoblastic%2520cell%2520line%253aMEG-01.CNhs11859.10752-110D5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/leukemia%252c%2520chronic%2520megakaryoblastic%2520cell%2520line%253aMEG-01.CNhs11859.10752-110D5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/leukemia%252c%2520chronic%2520megakaryoblastic%2520cell%2520line%253aMEG-01.CNhs11859.10752-110D5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10752-110D5 | |||
|is_a=EFO:0002091;;FF:0000210;;FF:0102581 | |||
|is_obsolete= | |||
|library_id=CNhs11859 | |||
|library_id_phase_based=2:CNhs11859 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10752 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10752 | |||
|name=leukemia, chronic megakaryoblastic cell line:MEG-01 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs11859,LSID830,release010,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.0136123497969953,0,-0.128000556201778,0.211544866682219,0,0,0,0.00346010663282764,0,0,0,0,0.0660220147767975,0,0,0,0,-0.0873009955716302,0,0,0,0.130146053995763,0,0.49922490903234,0,0,0.127335518212664,0,0,0,0,0,0,0,0,0,0,0.0956147761340415,0,-0.146667317146056,0.0956147761340415,0,0,0,0,0,0,0,0.0087959862755644,0,0,0,0.0342643952743103,0,-0.0316122588044999,0.0342643952743103,0.481778114787324,0,0,-0.0630792319387867,0,0,0,0,0,0,0,0,0.0342643952743103,0,0.0342643952743103,0,0,0.0342643952743103,0,0,0,0,0,0,0.00947378634483019,0,0,0,0,0,0,0,-0.0553860669588173,-0.036373665956316,0,0,0.0501432050255539,0,0.181407482893838,0.171068605059192,0,0,0,0,0,0,0.0342643952743103,0,0,0,0.171286743720091,0,0,0,0,0,0,0.0113182014618059,0.760525480692261,0,0,-0.0908423238199834,-0.372693858895629,0,0,0.16648732138936,0,0.0342643952743103,0 | |||
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| |||
|rna_box=110 | |||
|rna_catalog_number= | |||
|rna_concentration=1.53012 | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230=2.1 | |||
|rna_od260/280=2.08 | |||
|rna_position=D5 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=110D5 | |||
|rna_weight_ug=68.8554 | |||
|rnaseq_library_id=RDhi10081 | |||
|sample_age=56 | |||
|sample_category=cell lines | |||
|sample_cell_catalog=ifo50151 | |||
|sample_cell_line=MEG-01 | |||
|sample_cell_lot= | |||
|sample_cell_type=megakaryoblast | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=JAPAN HEALTH SCIENCES FOUNDATION - Health Science Research Resources Bank | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease=leukemia, chronic megakaryoblastic | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity=unknown | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.37003324669542e-299!GO:0043227;membrane-bound organelle;2.18233229723716e-258!GO:0043231;intracellular membrane-bound organelle;6.74149352689978e-258!GO:0043226;organelle;1.53956839275035e-250!GO:0043229;intracellular organelle;1.10939655905698e-249!GO:0005737;cytoplasm;3.70661429516212e-179!GO:0044422;organelle part;2.51458253971768e-155!GO:0044446;intracellular organelle part;1.63800381669225e-153!GO:0005634;nucleus;3.23476503724438e-136!GO:0044237;cellular metabolic process;1.09101365671044e-131!GO:0044238;primary metabolic process;4.75497108633559e-127!GO:0043170;macromolecule metabolic process;2.80977895099972e-122!GO:0044444;cytoplasmic part;3.41636672928996e-122!GO:0032991;macromolecular complex;8.49604925751267e-108!GO:0030529;ribonucleoprotein complex;4.19261662603046e-101!GO:0044428;nuclear part;1.05399982446738e-95!GO:0043233;organelle lumen;1.67624508358174e-92!GO:0031974;membrane-enclosed lumen;1.67624508358174e-92!GO:0003723;RNA binding;2.75537042433549e-91!GO:0043283;biopolymer metabolic process;6.35512586265046e-83!GO:0010467;gene expression;4.51280318646702e-79!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;1.42502971480158e-74!GO:0005739;mitochondrion;1.38756245778951e-72!GO:0005515;protein binding;5.38117831388811e-71!GO:0006412;translation;5.9323832629947e-63!GO:0006396;RNA processing;2.86513610640107e-62!GO:0031981;nuclear lumen;1.12389151588409e-59!GO:0005840;ribosome;7.4693749668928e-57!GO:0019538;protein metabolic process;5.02801884343018e-55!GO:0003676;nucleic acid binding;5.02801884343018e-55!GO:0043234;protein complex;2.45915302177163e-51!GO:0009059;macromolecule biosynthetic process;2.04596769053881e-50!GO:0044267;cellular protein metabolic process;3.68819537855078e-50!GO:0009058;biosynthetic process;1.19669854334218e-49!GO:0044260;cellular macromolecule metabolic process;1.51982492594121e-49!GO:0003735;structural constituent of ribosome;2.62061706567263e-49!GO:0016071;mRNA metabolic process;2.05877143908055e-47!GO:0044249;cellular biosynthetic process;8.32842678738018e-47!GO:0031090;organelle membrane;9.02532962004344e-47!GO:0016043;cellular component organization and biogenesis;1.56521747073434e-46!GO:0044429;mitochondrial part;2.85531427441773e-46!GO:0031967;organelle envelope;4.58443144512763e-44!GO:0016070;RNA metabolic process;1.04600716392923e-43!GO:0031975;envelope;1.25310661407039e-43!GO:0033036;macromolecule localization;1.95575107040736e-43!GO:0033279;ribosomal subunit;2.62261788880772e-43!GO:0008380;RNA splicing;3.86971600536667e-43!GO:0006259;DNA metabolic process;2.5317147823024e-41!GO:0015031;protein transport;1.59082233041446e-40!GO:0006397;mRNA processing;2.0812851073616e-40!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.28700298756579e-40!GO:0006996;organelle organization and biogenesis;7.14250437017691e-39!GO:0008104;protein localization;1.0569775618408e-38!GO:0065003;macromolecular complex assembly;1.45693593154479e-38!GO:0005829;cytosol;2.95861968374648e-38!GO:0045184;establishment of protein localization;7.75263051007501e-38!GO:0005654;nucleoplasm;8.61710811305042e-37!GO:0022607;cellular component assembly;8.75528240339286e-35!GO:0043228;non-membrane-bound organelle;1.83993256314318e-34!GO:0043232;intracellular non-membrane-bound organelle;1.83993256314318e-34!GO:0046907;intracellular transport;1.30944762363304e-33!GO:0000166;nucleotide binding;4.84897845788488e-33!GO:0005681;spliceosome;6.69982103760618e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);2.32032347228633e-31!GO:0007049;cell cycle;3.07646850126995e-30!GO:0044451;nucleoplasm part;1.91256446878652e-29!GO:0005740;mitochondrial envelope;1.39725586920196e-28!GO:0006886;intracellular protein transport;1.91080300801807e-28!GO:0044445;cytosolic part;2.17020973482606e-28!GO:0019866;organelle inner membrane;1.41675766300011e-27!GO:0031966;mitochondrial membrane;1.62834563994899e-26!GO:0051649;establishment of cellular localization;2.36958983434524e-25!GO:0005743;mitochondrial inner membrane;4.53115396204435e-25!GO:0051641;cellular localization;9.81638479346749e-25!GO:0016462;pyrophosphatase activity;2.61768894402402e-24!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.45193922631357e-24!GO:0016817;hydrolase activity, acting on acid anhydrides;6.95071045357434e-24!GO:0032553;ribonucleotide binding;8.25477082694718e-24!GO:0032555;purine ribonucleotide binding;8.25477082694718e-24!GO:0005730;nucleolus;9.28548566678067e-24!GO:0017111;nucleoside-triphosphatase activity;2.91088687057149e-23!GO:0031980;mitochondrial lumen;1.17067432255508e-22!GO:0005759;mitochondrial matrix;1.17067432255508e-22!GO:0006974;response to DNA damage stimulus;1.2087995340407e-22!GO:0015935;small ribosomal subunit;2.10342703959975e-22!GO:0017076;purine nucleotide binding;2.19385368919756e-22!GO:0022402;cell cycle process;3.14183507106159e-22!GO:0016874;ligase activity;5.32620676389174e-22!GO:0015934;large ribosomal subunit;6.25906516403475e-22!GO:0022618;protein-RNA complex assembly;1.05839868194373e-21!GO:0005694;chromosome;2.75583915617267e-21!GO:0006457;protein folding;4.57627384060178e-21!GO:0005524;ATP binding;5.71664466605281e-21!GO:0032559;adenyl ribonucleotide binding;7.68482059614153e-21!GO:0006119;oxidative phosphorylation;1.02139680527648e-20!GO:0000278;mitotic cell cycle;1.66212231044398e-20!GO:0051276;chromosome organization and biogenesis;2.44252783985701e-20!GO:0006512;ubiquitin cycle;3.18587457995732e-20!GO:0044455;mitochondrial membrane part;1.31333146582508e-19!GO:0042254;ribosome biogenesis and assembly;1.35881926204964e-19!GO:0012505;endomembrane system;1.5425755004995e-19!GO:0006281;DNA repair;1.82826998760818e-19!GO:0030554;adenyl nucleotide binding;3.51898094825884e-19!GO:0008135;translation factor activity, nucleic acid binding;8.77495101884536e-19!GO:0044427;chromosomal part;2.61699713005272e-18!GO:0044265;cellular macromolecule catabolic process;4.57458505346161e-18!GO:0008134;transcription factor binding;8.5670717831344e-18!GO:0043412;biopolymer modification;2.04985542207443e-17!GO:0022403;cell cycle phase;5.25938665943649e-17!GO:0043285;biopolymer catabolic process;6.26257992819827e-17!GO:0019941;modification-dependent protein catabolic process;8.95918668890373e-17!GO:0043632;modification-dependent macromolecule catabolic process;8.95918668890373e-17!GO:0051603;proteolysis involved in cellular protein catabolic process;9.37648988008456e-17!GO:0050794;regulation of cellular process;1.1825963951225e-16!GO:0006325;establishment and/or maintenance of chromatin architecture;1.49552059682584e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.12841431429912e-16!GO:0006511;ubiquitin-dependent protein catabolic process;2.21807185682033e-16!GO:0044257;cellular protein catabolic process;2.88965683725781e-16!GO:0012501;programmed cell death;2.92133529396891e-16!GO:0006915;apoptosis;4.61836556753037e-16!GO:0005635;nuclear envelope;4.78688656202286e-16!GO:0016604;nuclear body;5.84204519467395e-16!GO:0005746;mitochondrial respiratory chain;6.0529239214226e-16!GO:0006323;DNA packaging;7.91547313567889e-16!GO:0006260;DNA replication;9.41781961462764e-16!GO:0019222;regulation of metabolic process;1.04418963782727e-15!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);1.06646857315501e-15!GO:0005761;mitochondrial ribosome;1.70395402748391e-15!GO:0000313;organellar ribosome;1.70395402748391e-15!GO:0051082;unfolded protein binding;1.72414939796362e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;1.74870492449783e-15!GO:0000375;RNA splicing, via transesterification reactions;1.74870492449783e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.74870492449783e-15!GO:0006605;protein targeting;2.76178892944117e-15!GO:0006464;protein modification process;2.90878353454092e-15!GO:0009057;macromolecule catabolic process;4.30184438053195e-15!GO:0009719;response to endogenous stimulus;4.32880628328358e-15!GO:0000087;M phase of mitotic cell cycle;6.63116404180232e-15!GO:0044453;nuclear membrane part;6.88715609443254e-15!GO:0000502;proteasome complex (sensu Eukaryota);6.8926264986063e-15!GO:0004386;helicase activity;7.26940148962046e-15!GO:0031965;nuclear membrane;8.60994542520926e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;8.90335036171081e-15!GO:0050136;NADH dehydrogenase (quinone) activity;8.9243266091681e-15!GO:0003954;NADH dehydrogenase activity;8.9243266091681e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;8.9243266091681e-15!GO:0048770;pigment granule;9.02806517141575e-15!GO:0042470;melanosome;9.02806517141575e-15!GO:0006399;tRNA metabolic process;9.11625757901954e-15!GO:0016887;ATPase activity;1.01709997317483e-14!GO:0008219;cell death;1.03363265246825e-14!GO:0016265;death;1.03363265246825e-14!GO:0007067;mitosis;1.29946013362661e-14!GO:0042623;ATPase activity, coupled;1.38034120557345e-14!GO:0044248;cellular catabolic process;1.77034183933932e-14!GO:0003743;translation initiation factor activity;2.50732911522635e-14!GO:0051186;cofactor metabolic process;8.46618259122148e-14!GO:0005643;nuclear pore;1.19033553717109e-13!GO:0006366;transcription from RNA polymerase II promoter;1.24550938171481e-13!GO:0030163;protein catabolic process;1.7986502081714e-13!GO:0000279;M phase;2.92902396250465e-13!GO:0006413;translational initiation;3.04482159430622e-13!GO:0050657;nucleic acid transport;3.04482159430622e-13!GO:0051236;establishment of RNA localization;3.04482159430622e-13!GO:0050658;RNA transport;3.04482159430622e-13!GO:0008026;ATP-dependent helicase activity;3.19581810122904e-13!GO:0006403;RNA localization;3.63280364223615e-13!GO:0051301;cell division;4.05155264416718e-13!GO:0043687;post-translational protein modification;4.28801731617234e-13!GO:0006364;rRNA processing;4.8317895247729e-13!GO:0016072;rRNA metabolic process;6.54926756804164e-13!GO:0030964;NADH dehydrogenase complex (quinone);7.18690317297611e-13!GO:0045271;respiratory chain complex I;7.18690317297611e-13!GO:0005747;mitochondrial respiratory chain complex I;7.18690317297611e-13!GO:0042775;organelle ATP synthesis coupled electron transport;7.82948033358943e-13!GO:0042773;ATP synthesis coupled electron transport;7.82948033358943e-13!GO:0031323;regulation of cellular metabolic process;9.59582727835315e-13!GO:0065004;protein-DNA complex assembly;1.13580943661906e-12!GO:0006913;nucleocytoplasmic transport;1.23763794018341e-12!GO:0006350;transcription;1.70627400465079e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;2.53332016516701e-12!GO:0005783;endoplasmic reticulum;2.86264951451925e-12!GO:0051169;nuclear transport;2.86264951451925e-12!GO:0003712;transcription cofactor activity;2.940859367522e-12!GO:0050789;regulation of biological process;4.93945137657536e-12!GO:0005794;Golgi apparatus;6.33866166676895e-12!GO:0065002;intracellular protein transport across a membrane;9.73281317748857e-12!GO:0044432;endoplasmic reticulum part;1.02287269571584e-11!GO:0016607;nuclear speck;1.19942613203021e-11!GO:0006446;regulation of translational initiation;1.36162135385743e-11!GO:0006333;chromatin assembly or disassembly;1.88811934709549e-11!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;2.87622469041451e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.30530362052214e-11!GO:0051028;mRNA transport;3.56950040580938e-11!GO:0016568;chromatin modification;3.56950040580938e-11!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;3.71369569993251e-11!GO:0004812;aminoacyl-tRNA ligase activity;3.71369569993251e-11!GO:0016875;ligase activity, forming carbon-oxygen bonds;3.71369569993251e-11!GO:0000785;chromatin;3.7733092233249e-11!GO:0010468;regulation of gene expression;6.34450133998096e-11!GO:0046930;pore complex;6.4794175907545e-11!GO:0051726;regulation of cell cycle;6.83397543876673e-11!GO:0043038;amino acid activation;7.90452869813602e-11!GO:0006418;tRNA aminoacylation for protein translation;7.90452869813602e-11!GO:0043039;tRNA aminoacylation;7.90452869813602e-11!GO:0048193;Golgi vesicle transport;8.32227543307696e-11!GO:0006732;coenzyme metabolic process;8.95135384553433e-11!GO:0000074;regulation of progression through cell cycle;9.64490594711112e-11!GO:0017038;protein import;2.49318981417774e-10!GO:0016192;vesicle-mediated transport;3.03536826296113e-10!GO:0030532;small nuclear ribonucleoprotein complex;6.3886179769972e-10!GO:0019219;regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.69134780198373e-10!GO:0016779;nucleotidyltransferase activity;7.66679617426191e-10!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;8.19852477267877e-10!GO:0051188;cofactor biosynthetic process;8.5705980579375e-10!GO:0032774;RNA biosynthetic process;9.27105559947934e-10!GO:0006461;protein complex assembly;9.3248939453816e-10!GO:0006351;transcription, DNA-dependent;1.1198239069348e-09!GO:0016740;transferase activity;1.6718277064652e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;2.14861646257395e-09!GO:0008565;protein transporter activity;3.2910861225313e-09!GO:0005793;ER-Golgi intermediate compartment;4.7773736054635e-09!GO:0042981;regulation of apoptosis;6.08114003105891e-09!GO:0043067;regulation of programmed cell death;6.08824379222341e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;7.43145947291085e-09!GO:0043566;structure-specific DNA binding;8.67579988120546e-09!GO:0003697;single-stranded DNA binding;9.96816081639584e-09!GO:0051246;regulation of protein metabolic process;9.97115594094174e-09!GO:0006163;purine nucleotide metabolic process;1.40442270847207e-08!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.49837238492462e-08!GO:0006793;phosphorus metabolic process;1.63259270855989e-08!GO:0006796;phosphate metabolic process;1.63259270855989e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.04043249136852e-08!GO:0007005;mitochondrion organization and biogenesis;2.24984684255757e-08!GO:0005789;endoplasmic reticulum membrane;2.26818150093428e-08!GO:0009259;ribonucleotide metabolic process;2.47315805659655e-08!GO:0045449;regulation of transcription;2.71968038788502e-08!GO:0048523;negative regulation of cellular process;2.84734635186488e-08!GO:0006164;purine nucleotide biosynthetic process;3.0157521364672e-08!GO:0003677;DNA binding;3.84307011770721e-08!GO:0065007;biological regulation;4.41359763053032e-08!GO:0008639;small protein conjugating enzyme activity;5.06891287569583e-08!GO:0006261;DNA-dependent DNA replication;5.9731835053864e-08!GO:0019787;small conjugating protein ligase activity;8.06391475635881e-08!GO:0006334;nucleosome assembly;8.39432065760374e-08!GO:0009055;electron carrier activity;8.87692963109227e-08!GO:0004842;ubiquitin-protein ligase activity;1.0469345811329e-07!GO:0005667;transcription factor complex;1.23428824839757e-07!GO:0009150;purine ribonucleotide metabolic process;1.29666735750324e-07!GO:0009260;ribonucleotide biosynthetic process;1.53807795851791e-07!GO:0016310;phosphorylation;1.5882704545877e-07!GO:0009108;coenzyme biosynthetic process;1.67282540461752e-07!GO:0031497;chromatin assembly;1.98018025432512e-07!GO:0015986;ATP synthesis coupled proton transport;2.46752330715273e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;2.46752330715273e-07!GO:0051170;nuclear import;2.66650013428348e-07!GO:0016881;acid-amino acid ligase activity;2.74779650649622e-07!GO:0009056;catabolic process;2.78338260844576e-07!GO:0009152;purine ribonucleotide biosynthetic process;2.8458945865667e-07!GO:0051329;interphase of mitotic cell cycle;2.99400111507222e-07!GO:0019829;cation-transporting ATPase activity;3.01824395611981e-07!GO:0006357;regulation of transcription from RNA polymerase II promoter;3.81669596466261e-07!GO:0005768;endosome;3.82560814966725e-07!GO:0003899;DNA-directed RNA polymerase activity;3.99341888993412e-07!GO:0009060;aerobic respiration;4.49214426238779e-07!GO:0051325;interphase;5.18840937586719e-07!GO:0048519;negative regulation of biological process;5.50214845392861e-07!GO:0000245;spliceosome assembly;6.13577413435188e-07!GO:0006606;protein import into nucleus;6.21426115503334e-07!GO:0031324;negative regulation of cellular metabolic process;6.75227193754981e-07!GO:0006355;regulation of transcription, DNA-dependent;7.71678786027612e-07!GO:0003924;GTPase activity;8.4226720132498e-07!GO:0009141;nucleoside triphosphate metabolic process;1.00753892337024e-06!GO:0045259;proton-transporting ATP synthase complex;1.05947315689549e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.09680432718965e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.09680432718965e-06!GO:0009199;ribonucleoside triphosphate metabolic process;1.22285269057733e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.29878374562548e-06!GO:0003713;transcription coactivator activity;1.39313761007273e-06!GO:0016563;transcription activator activity;1.43800273049022e-06!GO:0016564;transcription repressor activity;1.50234449030134e-06!GO:0043069;negative regulation of programmed cell death;2.01989267098515e-06!GO:0019899;enzyme binding;2.35549709751874e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.35768328579678e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.35768328579678e-06!GO:0000775;chromosome, pericentric region;2.36629806764547e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;2.49937873146856e-06!GO:0009144;purine nucleoside triphosphate metabolic process;2.49937873146856e-06!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.61129365267906e-06!GO:0015630;microtubule cytoskeleton;3.64745620813137e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;3.96107786411528e-06!GO:0003724;RNA helicase activity;3.97039432673825e-06!GO:0006754;ATP biosynthetic process;4.02513973226814e-06!GO:0006753;nucleoside phosphate metabolic process;4.02513973226814e-06!GO:0048475;coated membrane;4.20166026434118e-06!GO:0030117;membrane coat;4.20166026434118e-06!GO:0044431;Golgi apparatus part;4.22217054174916e-06!GO:0006752;group transfer coenzyme metabolic process;4.27236346521031e-06!GO:0005839;proteasome core complex (sensu Eukaryota);4.34402407317428e-06!GO:0032446;protein modification by small protein conjugation;4.36484197192707e-06!GO:0003729;mRNA binding;4.36693182768503e-06!GO:0043066;negative regulation of apoptosis;4.47635934297892e-06!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;5.58696555698443e-06!GO:0046034;ATP metabolic process;5.70524845861665e-06!GO:0003714;transcription corepressor activity;5.96725956971091e-06!GO:0006520;amino acid metabolic process;6.24963501706538e-06!GO:0045333;cellular respiration;6.37179953780604e-06!GO:0005813;centrosome;6.38349532019744e-06!GO:0006352;transcription initiation;6.4122488884529e-06!GO:0007249;I-kappaB kinase/NF-kappaB cascade;6.45302447431612e-06!GO:0000075;cell cycle checkpoint;6.82952472065499e-06!GO:0008270;zinc ion binding;6.85559103058004e-06!GO:0015078;hydrogen ion transmembrane transporter activity;7.12277832796909e-06!GO:0051427;hormone receptor binding;7.82565313000238e-06!GO:0016567;protein ubiquitination;8.27573929414942e-06!GO:0005762;mitochondrial large ribosomal subunit;8.48995627166896e-06!GO:0000315;organellar large ribosomal subunit;8.48995627166896e-06!GO:0016363;nuclear matrix;8.78731299657827e-06!GO:0043623;cellular protein complex assembly;9.01761355153257e-06!GO:0005819;spindle;9.24777845914744e-06!GO:0006916;anti-apoptosis;1.04677144741133e-05!GO:0044452;nucleolar part;1.06210759452332e-05!GO:0008094;DNA-dependent ATPase activity;1.06210759452332e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;1.08053341946848e-05!GO:0006888;ER to Golgi vesicle-mediated transport;1.19413191709548e-05!GO:0009892;negative regulation of metabolic process;1.2088489479592e-05!GO:0005525;GTP binding;1.24704943034828e-05!GO:0016787;hydrolase activity;1.3712390590178e-05!GO:0016469;proton-transporting two-sector ATPase complex;1.37515059720539e-05!GO:0051168;nuclear export;1.48493316719996e-05!GO:0006613;cotranslational protein targeting to membrane;1.54792005381586e-05!GO:0008033;tRNA processing;1.55268075926609e-05!GO:0035257;nuclear hormone receptor binding;1.66540324919568e-05!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.74849681289874e-05!GO:0006401;RNA catabolic process;2.03921613526375e-05!GO:0004298;threonine endopeptidase activity;2.08801242398387e-05!GO:0016481;negative regulation of transcription;2.48010250905129e-05!GO:0019752;carboxylic acid metabolic process;2.48483060216765e-05!GO:0006082;organic acid metabolic process;2.58667462581728e-05!GO:0046914;transition metal ion binding;2.63609614482803e-05!GO:0005815;microtubule organizing center;2.70563266964231e-05!GO:0006099;tricarboxylic acid cycle;2.72727849931096e-05!GO:0046356;acetyl-CoA catabolic process;2.72727849931096e-05!GO:0008654;phospholipid biosynthetic process;2.85861197847688e-05!GO:0009117;nucleotide metabolic process;3.9434224435405e-05!GO:0000079;regulation of cyclin-dependent protein kinase activity;4.22907375389248e-05!GO:0003678;DNA helicase activity;4.53167085467706e-05!GO:0005788;endoplasmic reticulum lumen;4.76123461671253e-05!GO:0003682;chromatin binding;4.82741082309833e-05!GO:0031982;vesicle;5.12006578787865e-05!GO:0006084;acetyl-CoA metabolic process;5.18186519487077e-05!GO:0007243;protein kinase cascade;5.19125237000627e-05!GO:0005657;replication fork;5.81019461595761e-05!GO:0031988;membrane-bound vesicle;5.81019461595761e-05!GO:0044440;endosomal part;5.88498986702499e-05!GO:0010008;endosome membrane;5.88498986702499e-05!GO:0043021;ribonucleoprotein binding;6.12598534316708e-05!GO:0030880;RNA polymerase complex;6.40436089094605e-05!GO:0000314;organellar small ribosomal subunit;6.47549908538221e-05!GO:0005763;mitochondrial small ribosomal subunit;6.47549908538221e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.80009410708524e-05!GO:0006383;transcription from RNA polymerase III promoter;8.63128476835711e-05!GO:0030120;vesicle coat;8.86693512210845e-05!GO:0030662;coated vesicle membrane;8.86693512210845e-05!GO:0006310;DNA recombination;9.29518368951942e-05!GO:0006402;mRNA catabolic process;9.66785236777787e-05!GO:0006302;double-strand break repair;0.000101998558435414!GO:0003690;double-stranded DNA binding;0.000105135630112889!GO:0031072;heat shock protein binding;0.000111393251869605!GO:0009109;coenzyme catabolic process;0.000111872508748619!GO:0000151;ubiquitin ligase complex;0.000113705005059172!GO:0045454;cell redox homeostasis;0.000114719186972043!GO:0006839;mitochondrial transport;0.000115197634539913!GO:0043681;protein import into mitochondrion;0.000117286766568032!GO:0000139;Golgi membrane;0.000117345942006768!GO:0006626;protein targeting to mitochondrion;0.000133256033510385!GO:0019843;rRNA binding;0.000133373951240089!GO:0016023;cytoplasmic membrane-bound vesicle;0.000134876646817572!GO:0051187;cofactor catabolic process;0.000139445268591739!GO:0051052;regulation of DNA metabolic process;0.000139683178628374!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000143600013496111!GO:0000428;DNA-directed RNA polymerase complex;0.000143600013496111!GO:0031410;cytoplasmic vesicle;0.000161210600931269!GO:0004527;exonuclease activity;0.000161504505949706!GO:0008186;RNA-dependent ATPase activity;0.000179071872421777!GO:0006612;protein targeting to membrane;0.000191700740310276!GO:0032561;guanyl ribonucleotide binding;0.000195559104368711!GO:0019001;guanyl nucleotide binding;0.000195559104368711!GO:0005770;late endosome;0.000201660844770562!GO:0000059;protein import into nucleus, docking;0.000206542110247153!GO:0045786;negative regulation of progression through cell cycle;0.000216870924830551!GO:0016741;transferase activity, transferring one-carbon groups;0.000240639244648429!GO:0015077;monovalent inorganic cation transmembrane transporter activity;0.000246059301800429!GO:0006950;response to stress;0.000252036413432779!GO:0008632;apoptotic program;0.000259268527609716!GO:0006417;regulation of translation;0.000285979695507761!GO:0006414;translational elongation;0.000299734693224777!GO:0051789;response to protein stimulus;0.000306392787874807!GO:0006986;response to unfolded protein;0.000306392787874807!GO:0008168;methyltransferase activity;0.000322569345939741!GO:0006519;amino acid and derivative metabolic process;0.000360367539849041!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.000381869232204883!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000391138256920634!GO:0065009;regulation of a molecular function;0.000433338116406774!GO:0000049;tRNA binding;0.000435789063145476!GO:0000082;G1/S transition of mitotic cell cycle;0.000481207656983445!GO:0004004;ATP-dependent RNA helicase activity;0.000511433340386788!GO:0004518;nuclease activity;0.000514419232623825!GO:0006405;RNA export from nucleus;0.000570531284834439!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000616630900199784!GO:0016859;cis-trans isomerase activity;0.000620718703326607!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000642625270781865!GO:0005885;Arp2/3 protein complex;0.000670682211182581!GO:0016281;eukaryotic translation initiation factor 4F complex;0.000676124934980706!GO:0032508;DNA duplex unwinding;0.000683738355081891!GO:0032392;DNA geometric change;0.000683738355081891!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000713770701322368!GO:0005773;vacuole;0.000716026847215834!GO:0007006;mitochondrial membrane organization and biogenesis;0.000757440624213753!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000782380301392643!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000782380301392643!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000782380301392643!GO:0000776;kinetochore;0.000799486936587154!GO:0016251;general RNA polymerase II transcription factor activity;0.000809262960473238!GO:0046483;heterocycle metabolic process;0.000819549900446065!GO:0005684;U2-dependent spliceosome;0.000883555167229825!GO:0007093;mitotic cell cycle checkpoint;0.00098000985305793!GO:0006268;DNA unwinding during replication;0.00100169126568456!GO:0045045;secretory pathway;0.00100169126568456!GO:0016853;isomerase activity;0.00104007614217266!GO:0048471;perinuclear region of cytoplasm;0.00106027073561626!GO:0005769;early endosome;0.00106027073561626!GO:0006338;chromatin remodeling;0.00110527229736493!GO:0005741;mitochondrial outer membrane;0.00114993904710881!GO:0043065;positive regulation of apoptosis;0.00114993904710881!GO:0031968;organelle outer membrane;0.00115936263305655!GO:0006730;one-carbon compound metabolic process;0.00128571027946631!GO:0000096;sulfur amino acid metabolic process;0.00130714745692322!GO:0005798;Golgi-associated vesicle;0.00130714745692322!GO:0015631;tubulin binding;0.00132622123857819!GO:0005669;transcription factor TFIID complex;0.00136686906660797!GO:0007051;spindle organization and biogenesis;0.00137589848230576!GO:0019867;outer membrane;0.00143924892063092!GO:0048522;positive regulation of cellular process;0.00147964543830042!GO:0043068;positive regulation of programmed cell death;0.00148788485622472!GO:0000786;nucleosome;0.00150270241631719!GO:0046474;glycerophospholipid biosynthetic process;0.00153684178329953!GO:0005048;signal sequence binding;0.00159567447663853!GO:0032200;telomere organization and biogenesis;0.0015956888314836!GO:0000723;telomere maintenance;0.0015956888314836!GO:0042802;identical protein binding;0.0015978269490577!GO:0003684;damaged DNA binding;0.00162503558554554!GO:0051252;regulation of RNA metabolic process;0.00168855768087708!GO:0045892;negative regulation of transcription, DNA-dependent;0.00177285672560353!GO:0046467;membrane lipid biosynthetic process;0.00183930270079739!GO:0006275;regulation of DNA replication;0.00184191904085454!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.0018561898450652!GO:0015399;primary active transmembrane transporter activity;0.0018561898450652!GO:0007088;regulation of mitosis;0.00185750771796517!GO:0030867;rough endoplasmic reticulum membrane;0.00186265787530078!GO:0051087;chaperone binding;0.00190309073827468!GO:0048500;signal recognition particle;0.00195741356610238!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00200063118416694!GO:0000323;lytic vacuole;0.00206301620322808!GO:0005764;lysosome;0.00206301620322808!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00219950725243726!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00219950725243726!GO:0007050;cell cycle arrest;0.00225979780777061!GO:0043488;regulation of mRNA stability;0.00233593233215442!GO:0043487;regulation of RNA stability;0.00233593233215442!GO:0031252;leading edge;0.00239473688932528!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.00253445259914748!GO:0031326;regulation of cellular biosynthetic process;0.00255650130211638!GO:0003746;translation elongation factor activity;0.00277644265540024!GO:0022890;inorganic cation transmembrane transporter activity;0.00286687772680869!GO:0016272;prefoldin complex;0.00289073367295101!GO:0007059;chromosome segregation;0.00308205684092542!GO:0031970;organelle envelope lumen;0.00309823549092885!GO:0048468;cell development;0.003121332776524!GO:0005637;nuclear inner membrane;0.00321146115237577!GO:0008652;amino acid biosynthetic process;0.00325768726390404!GO:0009308;amine metabolic process;0.00326404676185626!GO:0030176;integral to endoplasmic reticulum membrane;0.00344858538531818!GO:0008637;apoptotic mitochondrial changes;0.00350654406300403!GO:0006611;protein export from nucleus;0.00360903887301761!GO:0030384;phosphoinositide metabolic process;0.00361664008618009!GO:0030521;androgen receptor signaling pathway;0.00367341606932442!GO:0009165;nucleotide biosynthetic process;0.0037421518275095!GO:0046489;phosphoinositide biosynthetic process;0.0037421518275095!GO:0000122;negative regulation of transcription from RNA polymerase II promoter;0.00382042709599672!GO:0030118;clathrin coat;0.00388813222117116!GO:0051287;NAD binding;0.0038987645584975!GO:0046966;thyroid hormone receptor binding;0.00394688042182945!GO:0008250;oligosaccharyl transferase complex;0.00397326484998717!GO:0008312;7S RNA binding;0.00400453488221066!GO:0006367;transcription initiation from RNA polymerase II promoter;0.00410008230197725!GO:0047485;protein N-terminus binding;0.00410183582255538!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00410362252513945!GO:0007264;small GTPase mediated signal transduction;0.00412469019020096!GO:0006595;polyamine metabolic process;0.00439533471917531!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00460907089122761!GO:0045047;protein targeting to ER;0.00460907089122761!GO:0003711;transcription elongation regulator activity;0.00471307567249384!GO:0004576;oligosaccharyl transferase activity;0.00472251038186221!GO:0015992;proton transport;0.00475052379956409!GO:0030036;actin cytoskeleton organization and biogenesis;0.00478290377558279!GO:0004003;ATP-dependent DNA helicase activity;0.00479042800302236!GO:0005665;DNA-directed RNA polymerase II, core complex;0.00480798510983104!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00490931961124803!GO:0032259;methylation;0.00497424383365937!GO:0033116;ER-Golgi intermediate compartment membrane;0.00500169094227049!GO:0009615;response to virus;0.00508390257426074!GO:0006807;nitrogen compound metabolic process;0.00508390257426074!GO:0006650;glycerophospholipid metabolic process;0.00508944843857712!GO:0005758;mitochondrial intermembrane space;0.00511562954218101!GO:0006818;hydrogen transport;0.00511902064835777!GO:0006144;purine base metabolic process;0.00522800984673682!GO:0006917;induction of apoptosis;0.00526490031798017!GO:0030218;erythrocyte differentiation;0.00527244001483784!GO:0008408;3'-5' exonuclease activity;0.00534035126201627!GO:0003702;RNA polymerase II transcription factor activity;0.00535743170607887!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00553237863407713!GO:0043414;biopolymer methylation;0.00557773382418308!GO:0015980;energy derivation by oxidation of organic compounds;0.00589477021243629!GO:0019783;small conjugating protein-specific protease activity;0.00593179987762146!GO:0007052;mitotic spindle organization and biogenesis;0.00600412089839169!GO:0030145;manganese ion binding;0.00600515191176185!GO:0043022;ribosome binding;0.00603747638950369!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00605003627704474!GO:0004532;exoribonuclease activity;0.00621416852157336!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00621416852157336!GO:0008139;nuclear localization sequence binding;0.00621416852157336!GO:0030518;steroid hormone receptor signaling pathway;0.00638802763038796!GO:0035258;steroid hormone receptor binding;0.00642090725797873!GO:0004843;ubiquitin-specific protease activity;0.0064394403641738!GO:0008234;cysteine-type peptidase activity;0.00659274914176943!GO:0050790;regulation of catalytic activity;0.00659274914176943!GO:0000792;heterochromatin;0.00708999311200781!GO:0012502;induction of programmed cell death;0.00720321409603339!GO:0016584;nucleosome positioning;0.00734025216301087!GO:0018196;peptidyl-asparagine modification;0.00734025216301087!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00734025216301087!GO:0048487;beta-tubulin binding;0.00761029379243961!GO:0032984;macromolecular complex disassembly;0.00767205877702576!GO:0051540;metal cluster binding;0.00770353870245509!GO:0051536;iron-sulfur cluster binding;0.00770353870245509!GO:0032940;secretion by cell;0.00795584976621809!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00795798325652607!GO:0009889;regulation of biosynthetic process;0.00804660323754156!GO:0006284;base-excision repair;0.00810586201168347!GO:0006891;intra-Golgi vesicle-mediated transport;0.00822392627676578!GO:0022411;cellular component disassembly;0.00822609577976928!GO:0016790;thiolester hydrolase activity;0.00840482884255246!GO:0000184;mRNA catabolic process, nonsense-mediated decay;0.00846024055776808!GO:0006376;mRNA splice site selection;0.00855446081297352!GO:0000389;nuclear mRNA 3'-splice site recognition;0.00855446081297352!GO:0006779;porphyrin biosynthetic process;0.00888298205928538!GO:0033014;tetrapyrrole biosynthetic process;0.00888298205928538!GO:0043492;ATPase activity, coupled to movement of substances;0.00901627613132304!GO:0000097;sulfur amino acid biosynthetic process;0.00909685346846118!GO:0000086;G2/M transition of mitotic cell cycle;0.00920660711960464!GO:0043241;protein complex disassembly;0.00940223314632364!GO:0043624;cellular protein complex disassembly;0.00947447330219524!GO:0006270;DNA replication initiation;0.00957771461086491!GO:0006778;porphyrin metabolic process;0.00957771461086491!GO:0033013;tetrapyrrole metabolic process;0.00957771461086491!GO:0043284;biopolymer biosynthetic process;0.0101413666301689!GO:0008017;microtubule binding;0.010365244172383!GO:0008097;5S rRNA binding;0.0104036488223034!GO:0016491;oxidoreductase activity;0.0104036488223034!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0104981353428275!GO:0005832;chaperonin-containing T-complex;0.010629863289798!GO:0019901;protein kinase binding;0.0111248374795301!GO:0000781;chromosome, telomeric region;0.0112647982094308!GO:0007010;cytoskeleton organization and biogenesis;0.0114062886220174!GO:0009451;RNA modification;0.0115214194387764!GO:0048518;positive regulation of biological process;0.0116188824885414!GO:0040029;regulation of gene expression, epigenetic;0.0117876537192555!GO:0016605;PML body;0.0118004471774143!GO:0004221;ubiquitin thiolesterase activity;0.0118217842928479!GO:0006984;ER-nuclear signaling pathway;0.0119666828272178!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.0119666828272178!GO:0030658;transport vesicle membrane;0.0120494032593234!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.012081070689544!GO:0008276;protein methyltransferase activity;0.0122396623479493!GO:0000339;RNA cap binding;0.0122754260963003!GO:0051539;4 iron, 4 sulfur cluster binding;0.0123147365801931!GO:0030119;AP-type membrane coat adaptor complex;0.012630489151655!GO:0004674;protein serine/threonine kinase activity;0.0126339904040613!GO:0008287;protein serine/threonine phosphatase complex;0.0126339904040613!GO:0022415;viral reproductive process;0.0127667473752647!GO:0030330;DNA damage response, signal transduction by p53 class mediator;0.0131226088817248!GO:0031124;mRNA 3'-end processing;0.0131413936290551!GO:0008610;lipid biosynthetic process;0.0135636729515751!GO:0009081;branched chain family amino acid metabolic process;0.0137074651311009!GO:0005874;microtubule;0.0140343968944384!GO:0008047;enzyme activator activity;0.0143664481792573!GO:0007259;JAK-STAT cascade;0.0143971802747694!GO:0007021;tubulin folding;0.0148428090764695!GO:0009303;rRNA transcription;0.0153321436051119!GO:0009967;positive regulation of signal transduction;0.0153359043412758!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.0154079282388444!GO:0000287;magnesium ion binding;0.0154079282388444!GO:0046426;negative regulation of JAK-STAT cascade;0.0156203397576005!GO:0006783;heme biosynthetic process;0.0166523189257166!GO:0004177;aminopeptidase activity;0.016845309917757!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0172510961035651!GO:0006506;GPI anchor biosynthetic process;0.0175207024082073!GO:0043130;ubiquitin binding;0.0175207024082073!GO:0032182;small conjugating protein binding;0.0175207024082073!GO:0031902;late endosome membrane;0.017829630016818!GO:0043189;H4/H2A histone acetyltransferase complex;0.0179287083392443!GO:0033673;negative regulation of kinase activity;0.0181910381200296!GO:0006469;negative regulation of protein kinase activity;0.0181910381200296!GO:0000178;exosome (RNase complex);0.0182762179081465!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0185958584997061!GO:0042168;heme metabolic process;0.0186699284440718!GO:0000228;nuclear chromosome;0.0188531001571733!GO:0009112;nucleobase metabolic process;0.0188805170476412!GO:0015036;disulfide oxidoreductase activity;0.0189843741317944!GO:0030522;intracellular receptor-mediated signaling pathway;0.0193407084817827!GO:0030131;clathrin adaptor complex;0.0194506770577572!GO:0051338;regulation of transferase activity;0.0196483674706567!GO:0042393;histone binding;0.0196967084358166!GO:0016407;acetyltransferase activity;0.0196967084358166!GO:0030663;COPI coated vesicle membrane;0.0197854023671968!GO:0030126;COPI vesicle coat;0.0197854023671968!GO:0007004;telomere maintenance via telomerase;0.0204885992629637!GO:0043549;regulation of kinase activity;0.0206972516371194!GO:0018193;peptidyl-amino acid modification;0.0207915091570314!GO:0006091;generation of precursor metabolites and energy;0.0209944590306156!GO:0051235;maintenance of localization;0.0209944590306156!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.0210603638840007!GO:0035267;NuA4 histone acetyltransferase complex;0.0219223041159958!GO:0030134;ER to Golgi transport vesicle;0.0221591656485077!GO:0045947;negative regulation of translational initiation;0.0221751855810851!GO:0006505;GPI anchor metabolic process;0.022521645474982!GO:0045893;positive regulation of transcription, DNA-dependent;0.0225242812905356!GO:0005876;spindle microtubule;0.0225522123690737!GO:0030660;Golgi-associated vesicle membrane;0.022674070693341!GO:0007242;intracellular signaling cascade;0.0228614728562667!GO:0030041;actin filament polymerization;0.0229707460598701!GO:0051920;peroxiredoxin activity;0.0229887830307924!GO:0030433;ER-associated protein catabolic process;0.0230907487338983!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0230907487338983!GO:0043596;nuclear replication fork;0.0231741039138825!GO:0051348;negative regulation of transferase activity;0.023421729856607!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.023422288160756!GO:0048144;fibroblast proliferation;0.0239699631947618!GO:0048145;regulation of fibroblast proliferation;0.0239699631947618!GO:0006378;mRNA polyadenylation;0.024696775986161!GO:0006541;glutamine metabolic process;0.0247077249189427!GO:0045815;positive regulation of gene expression, epigenetic;0.024830232860194!GO:0048037;cofactor binding;0.0248884457961757!GO:0006607;NLS-bearing substrate import into nucleus;0.0251317210046283!GO:0008538;proteasome activator activity;0.0251317210046283!GO:0008180;signalosome;0.0251317210046283!GO:0006406;mRNA export from nucleus;0.0251450331156867!GO:0000123;histone acetyltransferase complex;0.0252970600877297!GO:0031301;integral to organelle membrane;0.0253641453102798!GO:0000922;spindle pole;0.025713614625086!GO:0045859;regulation of protein kinase activity;0.025766310632288!GO:0043433;negative regulation of transcription factor activity;0.0259998300188113!GO:0050681;androgen receptor binding;0.0260303799194804!GO:0006497;protein amino acid lipidation;0.0267542236226063!GO:0000175;3'-5'-exoribonuclease activity;0.0269074113899231!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0272066554483884!GO:0006509;membrane protein ectodomain proteolysis;0.0273715749591689!GO:0033619;membrane protein proteolysis;0.0273715749591689!GO:0006289;nucleotide-excision repair;0.0273715749591689!GO:0048146;positive regulation of fibroblast proliferation;0.027409257985234!GO:0042771;DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis;0.0276383449512702!GO:0045941;positive regulation of transcription;0.0276383449512702!GO:0042158;lipoprotein biosynthetic process;0.0277991404036368!GO:0016197;endosome transport;0.0283732414130733!GO:0031371;ubiquitin conjugating enzyme complex;0.0286514590908118!GO:0030503;regulation of cell redox homeostasis;0.0286514590908118!GO:0045730;respiratory burst;0.0287002760684943!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0287317965484076!GO:0019900;kinase binding;0.0295450163216063!GO:0019079;viral genome replication;0.0296518736226614!GO:0006278;RNA-dependent DNA replication;0.0299603907501827!GO:0008213;protein amino acid alkylation;0.0299603907501827!GO:0006479;protein amino acid methylation;0.0299603907501827!GO:0008022;protein C-terminus binding;0.0300923980233718!GO:0008629;induction of apoptosis by intracellular signals;0.0301240542087966!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.03039094546302!GO:0009396;folic acid and derivative biosynthetic process;0.0305292610221423!GO:0001836;release of cytochrome c from mitochondria;0.0306575822938614!GO:0051101;regulation of DNA binding;0.0313028385047426!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0313193499557777!GO:0015002;heme-copper terminal oxidase activity;0.0313193499557777!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0313193499557777!GO:0004129;cytochrome-c oxidase activity;0.0313193499557777!GO:0005774;vacuolar membrane;0.0317481704310697!GO:0007017;microtubule-based process;0.0320382352316188!GO:0006596;polyamine biosynthetic process;0.0322649086549463!GO:0031123;RNA 3'-end processing;0.0324412745961995!GO:0051059;NF-kappaB binding;0.0329321737348234!GO:0030508;thiol-disulfide exchange intermediate activity;0.0333768024774109!GO:0030029;actin filament-based process;0.0335417855516895!GO:0003725;double-stranded RNA binding;0.0338393950318472!GO:0032594;protein transport within lipid bilayer;0.0340542675597779!GO:0032907;transforming growth factor-beta3 production;0.0340542675597779!GO:0032596;protein transport into lipid raft;0.0340542675597779!GO:0032910;regulation of transforming growth factor-beta3 production;0.0340542675597779!GO:0032595;B cell receptor transport within lipid bilayer;0.0340542675597779!GO:0033606;chemokine receptor transport within lipid bilayer;0.0340542675597779!GO:0032600;chemokine receptor transport out of lipid raft;0.0340542675597779!GO:0032599;protein transport out of lipid raft;0.0340542675597779!GO:0032597;B cell receptor transport into lipid raft;0.0340542675597779!GO:0032913;negative regulation of transforming growth factor-beta3 production;0.0340542675597779!GO:0003756;protein disulfide isomerase activity;0.0341529359727289!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0341529359727289!GO:0006400;tRNA modification;0.0344996094539484!GO:0008143;poly(A) binding;0.0349023553912094!GO:0005784;translocon complex;0.0349101425614678!GO:0004860;protein kinase inhibitor activity;0.0349400384332407!GO:0005096;GTPase activator activity;0.0354570175597907!GO:0030127;COPII vesicle coat;0.0354570175597907!GO:0012507;ER to Golgi transport vesicle membrane;0.0354570175597907!GO:0006360;transcription from RNA polymerase I promoter;0.0355475652718181!GO:0031570;DNA integrity checkpoint;0.0355475652718181!GO:0016044;membrane organization and biogenesis;0.0362387804292568!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0366488263064726!GO:0045039;protein import into mitochondrial inner membrane;0.0366488263064726!GO:0006220;pyrimidine nucleotide metabolic process;0.0368501329458761!GO:0004722;protein serine/threonine phosphatase activity;0.0368501329458761!GO:0022406;membrane docking;0.0368501329458761!GO:0048278;vesicle docking;0.0368501329458761!GO:0016835;carbon-oxygen lyase activity;0.0369383102479118!GO:0001726;ruffle;0.0369383102479118!GO:0035035;histone acetyltransferase binding;0.0375304359572541!GO:0045936;negative regulation of phosphate metabolic process;0.0377678604003646!GO:0002763;positive regulation of myeloid leukocyte differentiation;0.0381263682864816!GO:0042770;DNA damage response, signal transduction;0.0388525087943!GO:0050662;coenzyme binding;0.0388913597476919!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.038941077254818!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.038941077254818!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.038941077254818!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0389554068688928!GO:0000725;recombinational repair;0.0394148181039928!GO:0000724;double-strand break repair via homologous recombination;0.0394148181039928!GO:0005869;dynactin complex;0.0395275719295925!GO:0031901;early endosome membrane;0.0400536487185085!GO:0019210;kinase inhibitor activity;0.0403481806708592!GO:0046519;sphingoid metabolic process;0.040570807164941!GO:0045185;maintenance of protein localization;0.0408990809531631!GO:0006458;'de novo' protein folding;0.0413870766995412!GO:0051084;'de novo' posttranslational protein folding;0.0413870766995412!GO:0012506;vesicle membrane;0.0415627169853381!GO:0007265;Ras protein signal transduction;0.042149453527089!GO:0032040;small subunit processome;0.0424025405511644!GO:0060090;molecular adaptor activity;0.042573876226253!GO:0000118;histone deacetylase complex;0.0428996289623856!GO:0004540;ribonuclease activity;0.0430902268539137!GO:0042809;vitamin D receptor binding;0.0437192083119915!GO:0005092;GDP-dissociation inhibitor activity;0.0438117449037454!GO:0016408;C-acyltransferase activity;0.0438117449037454!GO:0030911;TPR domain binding;0.0444722947860369!GO:0046588;negative regulation of calcium-dependent cell-cell adhesion;0.0444722947860369!GO:0046586;regulation of calcium-dependent cell-cell adhesion;0.0444722947860369!GO:0046128;purine ribonucleoside metabolic process;0.0445139060795304!GO:0042278;purine nucleoside metabolic process;0.0445139060795304!GO:0006672;ceramide metabolic process;0.044575443585418!GO:0009083;branched chain family amino acid catabolic process;0.0447692049821641!GO:0051053;negative regulation of DNA metabolic process;0.0447692049821641!GO:0030659;cytoplasmic vesicle membrane;0.0450832569918238!GO:0051881;regulation of mitochondrial membrane potential;0.0455634397067624!GO:0000726;non-recombinational repair;0.0458345661813008!GO:0009070;serine family amino acid biosynthetic process;0.0462488707674039!GO:0031575;G1/S transition checkpoint;0.0462488707674039!GO:0008624;induction of apoptosis by extracellular signals;0.0462488707674039!GO:0030133;transport vesicle;0.0464530153878576!GO:0051098;regulation of binding;0.0467371120883155!GO:0000303;response to superoxide;0.0467939423763522!GO:0046983;protein dimerization activity;0.0470233620899837!GO:0008361;regulation of cell size;0.0471671473868609!GO:0000209;protein polyubiquitination;0.0472869512949717!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.0475239641674618!GO:0045737;positive regulation of cyclin-dependent protein kinase activity;0.0487222177360849!GO:0030137;COPI-coated vesicle;0.049144144968569!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0495200986166744!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0495200986166744 | |||
|sample_id=10752 | |||
|sample_note= | |||
|sample_sex=male | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=blood | |||
|top_motifs=GATA6:3.16373147958;POU2F1..3:2.22450166773;STAT5{A,B}:1.53540906131;MYB:1.49652843162;ALX1:1.46795285066;ZBTB16:1.43762813829;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.23527185324;bHLH_family:1.1652923212;AIRE:1.1540467445;EN1,2:1.12801792061;ELK1,4_GABP{A,B1}:1.11172811261;IKZF2:1.07101454692;NFY{A,B,C}:1.06167477292;PITX1..3:1.05256686545;PBX1:1.04247268087;NKX2-1,4:0.974925971391;TOPORS:0.87297266865;MYOD1:0.854480298608;ZNF143:0.85098475077;YY1:0.829326853744;POU1F1:0.815103741133;BREu{core}:0.798551580011;ELF1,2,4:0.782219895416;E2F1..5:0.743286382764;PAX8:0.679503769779;NRF1:0.647168497272;CUX2:0.639519420791;NKX3-1:0.636889106001;RBPJ:0.624599660592;CRX:0.603578695988;ATF4:0.549072369211;POU3F1..4:0.528158566802;ZNF148:0.513250373876;FOXP1:0.507576063934;HIF1A:0.506245537393;OCT4_SOX2{dimer}:0.505230846526;FOXQ1:0.49506981871;ATF5_CREB3:0.488524381037;FOX{I1,J2}:0.479035505795;STAT1,3:0.43976895329;CDX1,2,4:0.402828315466;FOXN1:0.383988152008;SPIB:0.377721989289;NKX6-1,2:0.342447753047;TFDP1:0.304732186766;HOXA9_MEIS1:0.296226478131;EVI1:0.270951472043;POU6F1:0.247556028791;NR5A1,2:0.243796453367;STAT2,4,6:0.238233590246;NR6A1:0.232518641537;IRF7:0.231158103891;SPI1:0.220929588412;ETS1,2:0.219904106833;TLX2:0.211156608374;CREB1:0.174871876105;NFE2:0.145434640536;HOX{A6,A7,B6,B7}:0.133897923027;DMAP1_NCOR{1,2}_SMARC:0.0992898272534;PAX4:0.0942213268676;SOX{8,9,10}:0.0888496992637;RUNX1..3:0.0857653900827;IRF1,2:0.0766642723078;PRRX1,2:0.0611192969918;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.000252489716184;SOX17:-0.00261315036452;ZNF384:-0.00462431040719;SRF:-0.00565600676448;PAX3,7:-0.0198136561867;AR:-0.0230369462568;NFIX:-0.0322733985702;LHX3,4:-0.0413208386908;CEBPA,B_DDIT3:-0.0714290476044;HES1:-0.0768695711394;PAX6:-0.0784287492252;NANOG{mouse}:-0.0854753490724;ARID5B:-0.0974725403214;HOX{A4,D4}:-0.103607473509;ADNP_IRX_SIX_ZHX:-0.11138369971;HNF4A_NR2F1,2:-0.112757861762;AHR_ARNT_ARNT2:-0.144159401941;ZFP161:-0.144584027155;FOXD3:-0.146557779173;ATF2:-0.150875461016;NKX2-3_NKX2-5:-0.168256412451;HOX{A5,B5}:-0.188734107341;HSF1,2:-0.190277582138;EP300:-0.200322589775;POU5F1:-0.228699783851;PDX1:-0.270255917947;GFI1:-0.272150903005;NHLH1,2:-0.27315880593;BACH2:-0.2737830145;TEF:-0.28334508169;FOXM1:-0.285844756775;FOSL2:-0.297588323784;FOX{F1,F2,J1}:-0.303059728041;SNAI1..3:-0.311274546038;HIC1:-0.323482360945;RREB1:-0.336387696152;NFKB1_REL_RELA:-0.341813622346;NFIL3:-0.373641089372;NANOG:-0.393170278473;ZNF238:-0.394621081492;RORA:-0.398008418564;FOXP3:-0.406497247982;ONECUT1,2:-0.406579249862;T:-0.425228025518;GATA4:-0.427882844738;PAX2:-0.429927721036;HLF:-0.449591066459;TBP:-0.461940638455;LEF1_TCF7_TCF7L1,2:-0.474099674523;NFE2L2:-0.476827912816;FOS_FOS{B,L1}_JUN{B,D}:-0.48432016808;GZF1:-0.484809748849;ZNF423:-0.496411994977;MED-1{core}:-0.496482960515;HBP1_HMGB_SSRP1_UBTF:-0.520949955955;SOX5:-0.526294526061;HNF1A:-0.528420943992;MTF1:-0.544330869207;FOXA2:-0.594657814471;PPARG:-0.598596932393;CDC5L:-0.599989947423;REST:-0.60129215751;RXR{A,B,G}:-0.603097987162;NFE2L1:-0.606509131845;ZEB1:-0.623609156721;GTF2I:-0.648070734537;KLF4:-0.660644746036;FOX{D1,D2}:-0.665950505476;ZBTB6:-0.670014673255;SREBF1,2:-0.680986352979;EGR1..3:-0.683622346493;XBP1:-0.687385583058;HAND1,2:-0.689696045389;GLI1..3:-0.693926233641;MYFfamily:-0.699716873721;UFEwm:-0.700355125746;VSX1,2:-0.701934468233;DBP:-0.705480216592;MZF1:-0.715226066332;RFX2..5_RFXANK_RFXAP:-0.719834910185;MEF2{A,B,C,D}:-0.721398404881;TFAP2B:-0.727023517069;TFAP2{A,C}:-0.739174770264;MAFB:-0.750046326914;BPTF:-0.753076664978;RXRA_VDR{dimer}:-0.755766692104;RFX1:-0.757812159613;NKX3-2:-0.781978817631;HMGA1,2:-0.793529283487;GCM1,2:-0.79746962649;SOX2:-0.84461503126;PATZ1:-0.84935854987;PAX1,9:-0.858544012554;GTF2A1,2:-0.862258444976;TLX1..3_NFIC{dimer}:-0.87379040625;TP53:-0.875802360501;NKX2-2,8:-0.905237847795;ZIC1..3:-0.90876598699;TGIF1:-0.913213775333;TFAP4:-0.91585843944;MYBL2:-0.928361554745;FOXO1,3,4:-0.93069378082;PAX5:-0.935068220585;SMAD1..7,9:-0.966042702013;SP1:-0.984163217869;MTE{core}:-0.989594663944;NFATC1..3:-1.01691008089;IKZF1:-1.03942263602;MAZ:-1.04061683184;JUN:-1.0475905735;TEAD1:-1.06467106713;SPZ1:-1.07572686675;PRDM1:-1.09051986091;ALX4:-1.12362593881;GFI1B:-1.12614066887;ESRRA:-1.14632887057;FOXL1:-1.16457314222;NR1H4:-1.17679970325;XCPE1{core}:-1.19430247901;TBX4,5:-1.22960202314;LMO2:-1.24058855518;ATF6:-1.3129251629;NR3C1:-1.36470808896;TAL1_TCF{3,4,12}:-1.44373926852;TFCP2:-1.5246259803;ESR1:-1.55853245783;HMX1:-1.89267619605;EBF1:-1.9138092093 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10752-110D5;search_select_hide=table117:FF:10752-110D5 | |||
}} | }} |
Latest revision as of 15:02, 3 June 2020
Name: | leukemia, chronic megakaryoblastic cell line:MEG-01 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs11859 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11859
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs11859
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.424 |
10 | 10 | 0.0395 |
100 | 100 | 0.937 |
101 | 101 | 0.189 |
102 | 102 | 0.411 |
103 | 103 | 0.686 |
104 | 104 | 0.973 |
105 | 105 | 0.484 |
106 | 106 | 0.114 |
107 | 107 | 0.172 |
108 | 108 | 0.394 |
109 | 109 | 0.234 |
11 | 11 | 0.394 |
110 | 110 | 0.863 |
111 | 111 | 0.0597 |
112 | 112 | 0.926 |
113 | 113 | 0.435 |
114 | 114 | 0.527 |
115 | 115 | 0.0173 |
116 | 116 | 0.299 |
117 | 117 | 0.0778 |
118 | 118 | 0.193 |
119 | 119 | 0.228 |
12 | 12 | 0.958 |
120 | 120 | 0.357 |
121 | 121 | 0.632 |
122 | 122 | 0.86 |
123 | 123 | 0.277 |
124 | 124 | 0.68 |
125 | 125 | 0.48 |
126 | 126 | 0.239 |
127 | 127 | 0.268 |
128 | 128 | 0.096 |
129 | 129 | 0.143 |
13 | 13 | 0.00192 |
130 | 130 | 0.705 |
131 | 131 | 0.547 |
132 | 132 | 0.186 |
133 | 133 | 0.172 |
134 | 134 | 0.527 |
135 | 135 | 0.0118 |
136 | 136 | 0.0247 |
137 | 137 | 0.817 |
138 | 138 | 0.987 |
139 | 139 | 0.153 |
14 | 14 | 0.504 |
140 | 140 | 0.571 |
141 | 141 | 0.284 |
142 | 142 | 0.434 |
143 | 143 | 0.442 |
144 | 144 | 0.534 |
145 | 145 | 0.363 |
146 | 146 | 0.154 |
147 | 147 | 0.213 |
148 | 148 | 0.37 |
149 | 149 | 0.00245 |
15 | 15 | 0.831 |
150 | 150 | 0.826 |
151 | 151 | 0.228 |
152 | 152 | 0.111 |
153 | 153 | 0.823 |
154 | 154 | 0.829 |
155 | 155 | 0.303 |
156 | 156 | 0.678 |
157 | 157 | 0.607 |
158 | 158 | 0.727 |
159 | 159 | 0.258 |
16 | 16 | 0.44 |
160 | 160 | 0.637 |
161 | 161 | 0.367 |
162 | 162 | 0.862 |
163 | 163 | 0.28 |
164 | 164 | 0.926 |
165 | 165 | 0.871 |
166 | 166 | 0.177 |
167 | 167 | 0.43 |
168 | 168 | 0.386 |
169 | 169 | 0.527 |
17 | 17 | 0.926 |
18 | 18 | 0.984 |
19 | 19 | 0.534 |
2 | 2 | 0.0258 |
20 | 20 | 0.0125 |
21 | 21 | 0.135 |
22 | 22 | 0.501 |
23 | 23 | 0.0019 |
24 | 24 | 0.279 |
25 | 25 | 0.521 |
26 | 26 | 0.289 |
27 | 27 | 0.0435 |
28 | 28 | 0.18 |
29 | 29 | 0.221 |
3 | 3 | 0.404 |
30 | 30 | 0.0094 |
31 | 31 | 0.399 |
32 | 32 | 0.0078 |
33 | 33 | 0.182 |
34 | 34 | 0.295 |
35 | 35 | 0.817 |
36 | 36 | 0.0389 |
37 | 37 | 0.302 |
38 | 38 | 0.972 |
39 | 39 | 0.211 |
4 | 4 | 0.0893 |
40 | 40 | 0.563 |
41 | 41 | 0.192 |
42 | 42 | 0.258 |
43 | 43 | 0.841 |
44 | 44 | 0.665 |
45 | 45 | 0.508 |
46 | 46 | 0.386 |
47 | 47 | 0.178 |
48 | 48 | 0.259 |
49 | 49 | 0.581 |
5 | 5 | 0.563 |
50 | 50 | 0.92 |
51 | 51 | 0.886 |
52 | 52 | 0.159 |
53 | 53 | 0.447 |
54 | 54 | 0.533 |
55 | 55 | 0.124 |
56 | 56 | 0.893 |
57 | 57 | 0.431 |
58 | 58 | 0.314 |
59 | 59 | 0.181 |
6 | 6 | 0.263 |
60 | 60 | 0.426 |
61 | 61 | 0.0645 |
62 | 62 | 0.779 |
63 | 63 | 0.803 |
64 | 64 | 0.648 |
65 | 65 | 0.263 |
66 | 66 | 3.18647e-7 |
67 | 67 | 0.478 |
68 | 68 | 0.208 |
69 | 69 | 0.675 |
7 | 7 | 0.276 |
70 | 70 | 0.794 |
71 | 71 | 0.114 |
72 | 72 | 0.848 |
73 | 73 | 0.965 |
74 | 74 | 0.228 |
75 | 75 | 0.00386 |
76 | 76 | 0.349 |
77 | 77 | 0.0424 |
78 | 78 | 0.038 |
79 | 79 | 0.0285 |
8 | 8 | 0.419 |
80 | 80 | 0.0127 |
81 | 81 | 0.509 |
82 | 82 | 0.254 |
83 | 83 | 0.402 |
84 | 84 | 0.986 |
85 | 85 | 0.357 |
86 | 86 | 0.919 |
87 | 87 | 0.123 |
88 | 88 | 0.453 |
89 | 89 | 0.131 |
9 | 9 | 0.35 |
90 | 90 | 0.134 |
91 | 91 | 0.145 |
92 | 92 | 0.314 |
93 | 93 | 0.925 |
94 | 94 | 0.878 |
95 | 95 | 0.0425 |
96 | 96 | 0.763 |
97 | 97 | 0.479 |
98 | 98 | 0.416 |
99 | 99 | 0.391 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs11859
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000210 human sample
FF:0102581 MEG-01 cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000988 (hematopoietic cell)
0000548 (animal cell)
0000763 (myeloid cell)
0002371 (somatic cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
0050686 (organ system cancer)
162 (cancer)
2531 (hematologic cancer)
14566 (disease of cellular proliferation)
0060083 (immune system cancer)
1240 (leukemia)
1036 (chronic leukemia)
8692 (myeloid leukemia)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0100737 (leukemia cell line sample)
0102580 (chronic myeloid leukemia cell line sample)
0101035 (hematopoietic cell line sample)
0100740 (myeloid leukemia cell line sample)
0102581 (MEG-01 cell sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000049 (common myeloid progenitor)
CL:0000134 (mesenchymal cell)