FF:11523-119I2: Difference between revisions
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{{f5samples | {{f5samples | ||
| | |DRA_sample_Accession=CAGE@SAMD00005826 | ||
| | |DRA_sample_Accession_RNASeq=sRNA-Seq@SAMD00005826 | ||
|accession_numbers=CAGE;DRX008307;DRR009179;DRZ000604;DRZ001989;DRZ011954;DRZ013339 | |||
|accession_numbers_RNASeq=sRNA-Seq;DRX037266;DRR041632;DRZ007274 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0002107,UBERON:0002100,UBERON:0001007,UBERON:0004119,UBERON:0000062,UBERON:0000475,UBERON:0000061,UBERON:0000465,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0009569,UBERON:0002368,UBERON:0005177,UBERON:0002365,UBERON:0005172,UBERON:0006925,UBERON:0002530,UBERON:0010317,UBERON:0005173,UBERON:0002417,UBERON:0000949,UBERON:0002330,UBERON:0000916,UBERON:0002423 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0002371,CL:0000181,CL:0000417,CL:0000668,CL:0000412,CL:0000255,CL:0000182 | |||
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| | |||
|ancestors_in_anatomy_facet=UBERON: | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
| | |ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000002,FF:0000101,FF:0000001,FF:0000078 | ||
|comment= | |||
|created_by= | |||
|creation_date= | |||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |||
|expression_enrichment_score=chr17:26697304..26697335,-!p1@SEBOX,p1@VTN!3.76!5722.99!SEBOX;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!3.15!1420.92!SEBOX;;chr17:26697257..26697268,-!p3@SEBOX,p3@VTN!2.89!778.28!SEBOX;;chr19:4153613..4153652,+!p1@CREB3L3!2.65!444.91!CREB3L3;;chr1:27240455..27240474,-!p1@NR0B2!2.55!352.38!NR0B2;;chr7:73038839..73038862,-!p1@MLXIPL!2.51!321.96!MLXIPL;;chr19:50432453..50432468,+!p1@ATF5!2.24!9041.44!ATF5;;chr12:100867653..100867677,+!p2@NR1H4!2.16!141.97!NR1H4;;chr1:214161272..214161322,+!p1@PROX1!2.15!193.94!PROX1;;chr15:53082521..53082549,-!p1@ONECUT1!2.09!122.95!ONECUT1;;chr12:100867627..100867652,+!p1@NR1H4!2.01!101.40!NR1H4;;chr17:53344945..53344977,+!p2@HLF!1.98!93.80!HLF;;chr1:161208013..161208038,-!p1@NR1I3!1.97!92.53!NR1I3;;chr20:43029862..43029900,+!p1@HNF4A!1.95!88.73!HNF4A;;chr1:201979743..201979762,+!p1@ELF3!1.82!64.65!ELF3;;chr1:161207986..161207998,-!p2@NR1I3!1.80!62.11!NR1I3;;chr1:151804244..151804310,-!p1@RORC!1.77!58.31!RORC;;chr19:33793430..33793447,-!p1@CEBPA!1.74!215.48!CEBPA;;chr3:126076242..126076257,-!p1@KLF15!1.72!63.38!KLF15;;chr14:38064429..38064486,-!p1@FOXA1!1.72!51.97!FOXA1;;chr19:46367576..46367592,+!p1@FOXA3!1.70!49.43!FOXA3;;chr1:199996733..199996781,+!p1@NR5A2!1.70!49.43!NR5A2;;chr20:43030002..43030028,+!p3@HNF4A!1.69!48.17!HNF4A;;chr3:126073018..126073036,-!p3@KLF15!1.69!48.17!KLF15;;chr17:17726907..17726958,-!p2@SREBF1!1.67!272.52!SREBF1;;chr8:71316428..71316459,-!p2@NCOA2!1.67!76.05!NCOA2;;chr19:50435736..50435781,+!p3@ATF5!1.67!62.11!ATF5;;chr17:26694979..26695007,-!p4@SEBOX!1.67!45.63!SEBOX;;chr17:53344980..53345011,+!p3@HLF!1.64!43.10!HLF;;chr8:76319876..76319926,+!p1@HNF4G!1.59!38.03!HNF4G;;chrX:66763856..66763896,+!p1@AR!1.55!49.43!AR;;chr17:26694801..26694812,-!p5@SEBOX!1.55!34.22!SEBOX;;chr19:50435673..50435690,+!p8@ATF5!1.53!32.96!ATF5;;chr17:15942934..15942957,-!p5@NCOR1!1.51!31.69!NCOR1;;chr6:151977801..151977813,+!p8@ESR1!1.51!31.69!ESR1;;chr7:73038867..73038878,-!p2@MLXIPL!1.51!31.69!MLXIPL;;chr1:161207964..161207975,-!p3@NR1I3!1.48!29.15!NR1I3;;chr22:41763452..41763466,+!p2@TEF!1.48!29.15!TEF;;chr12:100897130..100897149,+!p3@NR1H4!1.48!29.15!NR1H4;;chr11:113930425..113930471,+!p1@ZBTB16!1.44!38.03!ZBTB16;;chr1:61548225..61548299,+!p1@NFIA!1.42!314.35!NFIA;;chr22:29196433..29196445,-!p4@XBP1!1.42!27.89!XBP1;;chrX:131547625..131547644,-!p4@MBNL3!1.42!25.35!MBNL3;;chr3:126072967..126072981,-!p4@KLF15!1.40!24.08!KLF15;;chr1:201979703..201979721,+!p2@ELF3!1.40!24.08!ELF3;;chr20:22564895..22564910,-!p1@FOXA2!1.38!22.82!FOXA2;;chr20:62365971..62365986,+!p5@ZGPAT!1.38!22.82!ZGPAT;;chr1:209979467..209979494,-!p1@IRF6!1.35!24.08!IRF6;;chr1:214161328..214161348,+!p2@PROX1!1.35!21.55!PROX1;;chr16:51185172..51185197,-!p1@SALL1!1.35!21.55!SALL1;;chr16:51185318..51185348,-!p2@SALL1!1.35!21.55!SALL1;;chr6:126221034..126221056,+!p13@NCOA7!1.33!20.28!NCOA7;;chr1:214161358..214161377,+!p3@PROX1!1.33!20.28!PROX1;;chr1:2179370..2179409,+!p16@SKI!1.33!20.28!SKI;;chr2:46524897..46524911,+!p2@EPAS1!1.32!54.50!EPAS1;;chr7:113726357..113726443,+!p1@FOXP2!1.32!34.22!FOXP2;;chr10:94449703..94449718,+!p1@HHEX!1.31!73.52!HHEX;;chr22:29196492..29196503,-!p3@XBP1!1.30!29.15!XBP1;;chr7:97840743..97840786,+!p1@BHLHA15!1.30!19.01!BHLHA15;;chr18:55102598..55102623,+!p1@ONECUT2!1.30!19.01!ONECUT2;;chr3:126076264..126076305,-!p2@KLF15!1.28!25.35!KLF15;;chr17:17726892..17726903,-!p6@SREBF1!1.28!20.28!SREBF1;;chr17:26694940..26694949,-!p6@SEBOX!1.27!17.75!SEBOX;;chr1:199996702..199996732,+!p5@NR5A2!1.27!17.75!NR5A2;;chr8:71316403..71316427,-!p6@NCOA2!1.25!20.28!NCOA2;;chr20:62365987..62365998,+!p8@ZGPAT!1.24!16.48!ZGPAT;;chr12:100867736..100867750,+!p4@NR1H4!1.24!16.48!NR1H4;;chr11:113930291..113930339,+!p2@ZBTB16!1.22!25.35!ZBTB16;;chr9:137217986..137218049,+!p3@RXRA!1.21!43.10!RXRA;;chr12:24715376..24715432,-!p1@SOX5!1.21!19.01!SOX5;;chr19:4153719..4153730,+!p2@CREB3L3!1.21!15.21!CREB3L3;;chr17:26694831..26694842,-!p8@SEBOX!1.21!15.21!SEBOX;;chr22:46546494..46546525,+!p2@PPARA!1.20!29.15!PPARA;;chr15:60884706..60884743,-!p1@RORA!1.19!73.52!RORA;;chr17:17723702..17723721,-!p7@SREBF1!1.19!17.75!SREBF1;;chr17:26695013..26695024,-!p7@SEBOX!1.17!13.94!SEBOX;;chr18:55102628..55102646,+!p2@ONECUT2!1.17!13.94!ONECUT2;;chr9:137218281..137218340,+!p1@RXRA!1.14!357.45!RXRA;;chr17:15942958..15942973,-!p10@NCOR1!1.14!12.68!NCOR1;;chr1:42801540..42801562,-!p4@FOXJ3!1.14!12.68!FOXJ3;;chr12:100867695..100867706,+!p6@NR1H4!1.14!12.68!NR1H4;;chr12:121416340..121416360,+!p1@HNF1A!1.14!12.68!HNF1A;;chr11:47279248..47279264,+!p3@NR1H3!1.12!13.94!NR1H3;;chr17:53342311..53342400,+!p1@HLF!1.12!13.94!HLF;;chr9:22447422..22447483,+!p1@DMRTA1!1.09!11.41!DMRTA1;;chrX:66763914..66763933,+!p3@AR!1.09!11.41!AR;;chr2:180726040..180726052,-!p2@ZNF385B!1.09!11.41!ZNF385B;;chr7:73038865..73038866,-!p4@MLXIPL!1.09!11.41!MLXIPL;;chr7:73038889..73038905,-!p3@MLXIPL!1.09!11.41!MLXIPL;;chr12:24102576..24102623,-!p2@SOX5!1.09!11.41!SOX5;;chr6:126240380..126240430,+!p2@NCOA7!1.07!27.89!NCOA7;;chr11:61520075.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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000066;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000182;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000223;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000949;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001007;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002107;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002365;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002368;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002423;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0003929;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0005911;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0007499;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0009854 | |||
|ffid_belonging_in_development=CL:0000134,CL:0000223 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
| Line 66: | Line 43: | ||
|fonse_treatment= | |fonse_treatment= | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|is_a=EFO:0002091;;FF: | |hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Hepatocyte%252c%2520donor1.CNhs12340.11523-119I2.hg19.nobarcode.bam | ||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Hepatocyte%252c%2520donor1.CNhs12340.11523-119I2.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.primary_cell.hCAGE/Hepatocyte%252c%2520donor1.CNhs12340.11523-119I2.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Hepatocyte%252c%2520donor1.CNhs12340.11523-119I2.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.primary_cell.hCAGE/Hepatocyte%252c%2520donor1.CNhs12340.11523-119I2.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11523-119I2 | |||
|is_a=EFO:0002091;;FF:0000078 | |||
|is_obsolete= | |||
|library_id=CNhs12340 | |||
|library_id_phase_based=2:CNhs12340 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11523 | |||
|microRNAs_nonnovel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer/#/human#srna;sample;SRhi10066.AGTCAA.11523 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11523 | |||
|microRNAs_novel_srna=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2016/vis_viewer_novel/#/human#srna;sample;SRhi10066.AGTCAA.11523 | |||
|name=Hepatocyte, donor1 | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |||
|profile_hcage=CNhs12340,LSID913,release011,COMPLETED | |||
|profile_rnaseq= | |||
|profile_srnaseq=,,, | |||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
|repeat_enrich_byfamily=0,0,0,0,0,0,0,0.5211630023393,0.355556938823921,0.814474584726083,0.983093554984688,0,0,0,0,0,0,0,0,0,0,0,0,0,0.528158022077258,0,0,0,0.17777846941196,0,0.450443892807978,0,0,0.801809531069199,0,0,0,0,0,0,0,0,0,0,0,0,0.50642899621879,0.443938603457487,0,0,0,0,0,0,0,-0.0242150211128343,0,0,0,0,0,-0.0839305477320758,0,0.58448867118308,0,0,0.68585947281811,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.0628792039879575,0.17777846941196,0,0,-0.077287496640063,-0.211197402695869,0,0,0,0,0.257521587586215,0.53808023991081,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.400847729064139,0,0,0,0.637214835374452,0.999311875360379,0,0,0,0,0,0 | |||
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| |||
|rna_box=119 | |||
|rna_catalog_number=SC5205 | |||
|rna_concentration=1ug/ul | |||
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-TRIzol-isopropanol-v1.0 | |||
|rna_lot_number= | |||
|rna_od260/230= | |||
|rna_od260/280= | |||
|rna_position=I2 | |||
|rna_rin= | |||
|rna_sample_type=total RNA | |||
|rna_tube_id=119I2 | |||
|rna_weight_ug=10 | |||
|rnaseq_library_id=SRhi10066.AGTCAA | |||
|sample_age= | |||
|sample_category=primary cells | |||
|sample_cell_catalog=N/A | |||
|sample_cell_line= | |||
|sample_cell_lot=N/A | |||
|sample_cell_type=hepatocyte | |||
|sample_collaboration=FANTOM5 OSC CORE (contact: Al Forrest) | |||
|sample_company=Sciencell/3H | |||
|sample_description= | |||
|sample_dev_stage= | |||
|sample_disease= | |||
|sample_donor(cell lot)= | |||
|sample_ethnicity= | |||
|sample_experimental_condition= | |||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.99029188251143e-245!GO:0005737;cytoplasm;4.5996522677584e-206!GO:0044444;cytoplasmic part;5.5231169648728e-190!GO:0043227;membrane-bound organelle;8.89183460101219e-137!GO:0043231;intracellular membrane-bound organelle;8.89183460101219e-137!GO:0043226;organelle;4.45754768449274e-122!GO:0043229;intracellular organelle;8.21730901083244e-122!GO:0005739;mitochondrion;5.14014178519084e-120!GO:0044422;organelle part;5.00165761334687e-107!GO:0044446;intracellular organelle part;1.34827942662927e-105!GO:0044237;cellular metabolic process;1.30677360762189e-79!GO:0031090;organelle membrane;8.46629849126968e-76!GO:0044429;mitochondrial part;4.25574258331448e-74!GO:0044238;primary metabolic process;8.20312154321452e-72!GO:0009058;biosynthetic process;6.1735537955313e-65!GO:0043233;organelle lumen;1.40560611737149e-60!GO:0031974;membrane-enclosed lumen;1.40560611737149e-60!GO:0032991;macromolecular complex;7.28806084561439e-60!GO:0030529;ribonucleoprotein complex;2.90881898722392e-58!GO:0044249;cellular biosynthetic process;2.33234261812153e-55!GO:0031967;organelle envelope;9.62010961298774e-50!GO:0031975;envelope;2.43435775068218e-49!GO:0016491;oxidoreductase activity;7.79881077581297e-48!GO:0005740;mitochondrial envelope;1.6913533802221e-43!GO:0006082;organic acid metabolic process;9.82905170071672e-43!GO:0003723;RNA binding;1.40933760756767e-42!GO:0005783;endoplasmic reticulum;1.40933760756767e-42!GO:0019866;organelle inner membrane;2.74937947609774e-42!GO:0031966;mitochondrial membrane;4.92927937179374e-42!GO:0019752;carboxylic acid metabolic process;9.92916156827207e-42!GO:0005743;mitochondrial inner membrane;7.90094823372118e-41!GO:0019538;protein metabolic process;4.4123129571945e-40!GO:0031980;mitochondrial lumen;1.19460414502945e-39!GO:0005759;mitochondrial matrix;1.19460414502945e-39!GO:0009059;macromolecule biosynthetic process;1.3495459158871e-39!GO:0006412;translation;8.76026526636023e-39!GO:0005840;ribosome;1.08949607897069e-37!GO:0043170;macromolecule metabolic process;2.4444437456589e-37!GO:0033036;macromolecule localization;6.55122210575672e-37!GO:0044260;cellular macromolecule metabolic process;1.72950326947307e-36!GO:0044432;endoplasmic reticulum part;3.03729462985568e-36!GO:0044428;nuclear part;7.94526032081556e-36!GO:0005829;cytosol;1.4121191628521e-35!GO:0015031;protein transport;3.22216708507784e-35!GO:0044267;cellular protein metabolic process;8.58473252643572e-35!GO:0008104;protein localization;2.42896662794685e-34!GO:0045184;establishment of protein localization;3.60022868600571e-34!GO:0044248;cellular catabolic process;9.33396719128227e-34!GO:0006091;generation of precursor metabolites and energy;7.47742147994084e-33!GO:0042175;nuclear envelope-endoplasmic reticulum network;1.52622517789798e-31!GO:0012505;endomembrane system;2.06610197909332e-31!GO:0005789;endoplasmic reticulum membrane;2.54909774949187e-31!GO:0003735;structural constituent of ribosome;4.61531607565249e-31!GO:0005515;protein binding;2.46885007534547e-30!GO:0006396;RNA processing;2.90763603142504e-30!GO:0043234;protein complex;2.84500151650472e-28!GO:0051186;cofactor metabolic process;2.0826112567917e-27!GO:0033279;ribosomal subunit;1.08711036314952e-26!GO:0044255;cellular lipid metabolic process;4.2725226994837e-26!GO:0016071;mRNA metabolic process;8.02343124527287e-26!GO:0006629;lipid metabolic process;1.94939976992325e-25!GO:0006886;intracellular protein transport;3.62551054890596e-25!GO:0009056;catabolic process;1.14680861096887e-23!GO:0032787;monocarboxylic acid metabolic process;1.60033972601587e-23!GO:0008380;RNA splicing;2.12141677929342e-23!GO:0009055;electron carrier activity;2.68607886161907e-23!GO:0046907;intracellular transport;3.21873851912672e-23!GO:0048037;cofactor binding;4.29219201337386e-23!GO:0006119;oxidative phosphorylation;2.74149149327534e-22!GO:0044455;mitochondrial membrane part;4.71063877034628e-22!GO:0006732;coenzyme metabolic process;7.39654965761831e-22!GO:0031981;nuclear lumen;1.02562429038127e-21!GO:0006397;mRNA processing;2.25913125197887e-21!GO:0006118;electron transport;2.93128026718049e-21!GO:0016874;ligase activity;1.65280410976521e-19!GO:0006807;nitrogen compound metabolic process;5.26007738377356e-19!GO:0005746;mitochondrial respiratory chain;6.5739324706611e-19!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.31593808163258e-18!GO:0065003;macromolecular complex assembly;2.15489494919431e-18!GO:0050662;coenzyme binding;4.22356729875747e-17!GO:0005681;spliceosome;7.63338161048613e-17!GO:0016043;cellular component organization and biogenesis;1.27645654038435e-16!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;2.57376469005892e-16!GO:0009308;amine metabolic process;3.30676451920505e-16!GO:0044265;cellular macromolecule catabolic process;3.75282648127224e-16!GO:0050136;NADH dehydrogenase (quinone) activity;3.79055181372738e-16!GO:0003954;NADH dehydrogenase activity;3.79055181372738e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;3.79055181372738e-16!GO:0006520;amino acid metabolic process;7.39910739777199e-16!GO:0006066;alcohol metabolic process;8.44410505994635e-16!GO:0006519;amino acid and derivative metabolic process;2.3766602393947e-15!GO:0005830;cytosolic ribosome (sensu Eukaryota);3.21499578268708e-15!GO:0022607;cellular component assembly;3.21499578268708e-15!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;5.80500477207368e-15!GO:0030964;NADH dehydrogenase complex (quinone);1.10876830641721e-14!GO:0045271;respiratory chain complex I;1.10876830641721e-14!GO:0005747;mitochondrial respiratory chain complex I;1.10876830641721e-14!GO:0042775;organelle ATP synthesis coupled electron transport;1.10959861987829e-14!GO:0042773;ATP synthesis coupled electron transport;1.10959861987829e-14!GO:0005761;mitochondrial ribosome;1.2737452302372e-14!GO:0000313;organellar ribosome;1.2737452302372e-14!GO:0005777;peroxisome;1.42119818328122e-14!GO:0042579;microbody;1.42119818328122e-14!GO:0015935;small ribosomal subunit;3.07102901782968e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.28703929031554e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;4.37544812367757e-14!GO:0006457;protein folding;4.48144631735999e-14!GO:0005654;nucleoplasm;4.78879922639598e-14!GO:0051641;cellular localization;5.63143228025866e-14!GO:0051649;establishment of cellular localization;5.89026925123716e-14!GO:0022618;protein-RNA complex assembly;9.19716736328605e-14!GO:0016787;hydrolase activity;1.27698290389855e-13!GO:0044445;cytosolic part;2.17076215435633e-13!GO:0015934;large ribosomal subunit;2.18359893812637e-13!GO:0006631;fatty acid metabolic process;2.4629989106678e-13!GO:0000502;proteasome complex (sensu Eukaryota);2.93854178828849e-13!GO:0044262;cellular carbohydrate metabolic process;2.96237624243907e-13!GO:0009057;macromolecule catabolic process;3.88097450144444e-13!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;5.60294792569554e-13!GO:0016817;hydrolase activity, acting on acid anhydrides;6.520405591923e-13!GO:0051603;proteolysis involved in cellular protein catabolic process;6.65364889345231e-13!GO:0005634;nucleus;6.92618565263369e-13!GO:0016125;sterol metabolic process;8.37735533878774e-13!GO:0000166;nucleotide binding;8.53114265186766e-13!GO:0008135;translation factor activity, nucleic acid binding;9.81148286797316e-13!GO:0008202;steroid metabolic process;9.84012300869588e-13!GO:0016462;pyrophosphatase activity;1.02270809934079e-12!GO:0006605;protein targeting;1.06747168170412e-12!GO:0044451;nucleoplasm part;1.34798091308971e-12!GO:0019941;modification-dependent protein catabolic process;1.35421663285535e-12!GO:0043632;modification-dependent macromolecule catabolic process;1.35421663285535e-12!GO:0044257;cellular protein catabolic process;1.35559449485396e-12!GO:0006511;ubiquitin-dependent protein catabolic process;1.6252431259933e-12!GO:0051188;cofactor biosynthetic process;1.90911900939823e-12!GO:0005792;microsome;4.01871100405708e-12!GO:0051082;unfolded protein binding;4.65280257590742e-12!GO:0043285;biopolymer catabolic process;7.79094353849065e-12!GO:0017111;nucleoside-triphosphatase activity;7.92101492810197e-12!GO:0006950;response to stress;9.2212669728795e-12!GO:0005793;ER-Golgi intermediate compartment;1.31504422383833e-11!GO:0042598;vesicular fraction;1.54652764005216e-11!GO:0048770;pigment granule;2.32045579100555e-11!GO:0042470;melanosome;2.32045579100555e-11!GO:0008610;lipid biosynthetic process;2.73747249534065e-11!GO:0002526;acute inflammatory response;2.82063530988019e-11!GO:0006512;ubiquitin cycle;2.87370949459689e-11!GO:0008203;cholesterol metabolic process;3.22373184749806e-11!GO:0044270;nitrogen compound catabolic process;3.63319636088911e-11!GO:0009063;amino acid catabolic process;3.86487136219112e-11!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;3.88944466000424e-11!GO:0005794;Golgi apparatus;8.81664499551605e-11!GO:0046483;heterocycle metabolic process;9.92394596430493e-11!GO:0015980;energy derivation by oxidation of organic compounds;2.01670075780113e-10!GO:0009310;amine catabolic process;2.55138018629082e-10!GO:0048193;Golgi vesicle transport;4.53567750617343e-10!GO:0006446;regulation of translational initiation;5.22507530757921e-10!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;5.95825465351091e-10!GO:0016887;ATPase activity;8.73813456416442e-10!GO:0008134;transcription factor binding;9.68036159407072e-10!GO:0009060;aerobic respiration;1.19150624631005e-09!GO:0006413;translational initiation;1.32021837349396e-09!GO:0009108;coenzyme biosynthetic process;1.50138032988391e-09!GO:0045333;cellular respiration;1.95734426824437e-09!GO:0010467;gene expression;2.54729158135121e-09!GO:0016126;sterol biosynthetic process;2.91357034693449e-09!GO:0051187;cofactor catabolic process;3.23338088069193e-09!GO:0016192;vesicle-mediated transport;3.23338088069193e-09!GO:0030163;protein catabolic process;3.70807449168455e-09!GO:0016829;lyase activity;4.14216410023929e-09!GO:0006461;protein complex assembly;5.49271387093404e-09!GO:0005975;carbohydrate metabolic process;8.40649983909635e-09!GO:0003743;translation initiation factor activity;8.66556535324657e-09!GO:0006695;cholesterol biosynthetic process;9.35133082825015e-09!GO:0016740;transferase activity;1.09067867494319e-08!GO:0006084;acetyl-CoA metabolic process;1.12946575429023e-08!GO:0017076;purine nucleotide binding;1.29182979316217e-08!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.56848483444253e-08!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.56848483444253e-08!GO:0005730;nucleolus;1.69045526965883e-08!GO:0008219;cell death;2.05016013200386e-08!GO:0016265;death;2.05016013200386e-08!GO:0006958;complement activation, classical pathway;2.18528532556881e-08!GO:0006913;nucleocytoplasmic transport;2.25119619117454e-08!GO:0002455;humoral immune response mediated by circulating immunoglobulin;2.34440683918008e-08!GO:0016607;nuclear speck;2.55926250561363e-08!GO:0005773;vacuole;2.77974262574859e-08!GO:0006099;tricarboxylic acid cycle;3.09239026370251e-08!GO:0046356;acetyl-CoA catabolic process;3.09239026370251e-08!GO:0016604;nuclear body;3.10813077513887e-08!GO:0006915;apoptosis;3.22096275454025e-08!GO:0012501;programmed cell death;3.31205608897007e-08!GO:0002541;activation of plasma proteins during acute inflammatory response;3.67542477843471e-08!GO:0006956;complement activation;3.67542477843471e-08!GO:0051169;nuclear transport;3.92532207504662e-08!GO:0009109;coenzyme catabolic process;3.95996838043548e-08!GO:0005768;endosome;4.06376188424781e-08!GO:0000398;nuclear mRNA splicing, via spliceosome;4.24446852682285e-08!GO:0000375;RNA splicing, via transesterification reactions;4.24446852682285e-08!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;4.24446852682285e-08!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);4.40302081581699e-08!GO:0009259;ribonucleotide metabolic process;4.7764394140821e-08!GO:0042623;ATPase activity, coupled;4.77658563949869e-08!GO:0030554;adenyl nucleotide binding;5.64662308728803e-08!GO:0005506;iron ion binding;5.88859320602815e-08!GO:0046930;pore complex;7.18100365554716e-08!GO:0005635;nuclear envelope;8.45215890754962e-08!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);9.29715809253125e-08!GO:0019439;aromatic compound catabolic process;9.51339914363234e-08!GO:0019829;cation-transporting ATPase activity;1.30446470662965e-07!GO:0006163;purine nucleotide metabolic process;1.32214410945211e-07!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;1.3892903817922e-07!GO:0043283;biopolymer metabolic process;1.48472487753044e-07!GO:0000323;lytic vacuole;1.55578564751989e-07!GO:0005764;lysosome;1.55578564751989e-07!GO:0008565;protein transporter activity;1.81146242899244e-07!GO:0031965;nuclear membrane;1.81146242899244e-07!GO:0019842;vitamin binding;1.89418676691246e-07!GO:0017038;protein import;2.34518109147462e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.37503116377791e-07!GO:0006752;group transfer coenzyme metabolic process;2.75236991291611e-07!GO:0005996;monosaccharide metabolic process;4.07019726777647e-07!GO:0030120;vesicle coat;4.26963528353823e-07!GO:0030662;coated vesicle membrane;4.26963528353823e-07!GO:0015986;ATP synthesis coupled proton transport;4.28473386321455e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;4.28473386321455e-07!GO:0006888;ER to Golgi vesicle-mediated transport;4.79326330736109e-07!GO:0008652;amino acid biosynthetic process;5.06919894875852e-07!GO:0009260;ribonucleotide biosynthetic process;5.2061860159183e-07!GO:0006164;purine nucleotide biosynthetic process;5.80127390329286e-07!GO:0006996;organelle organization and biogenesis;5.83030645131331e-07!GO:0044453;nuclear membrane part;6.374698217733e-07!GO:0009199;ribonucleoside triphosphate metabolic process;6.80816974755231e-07!GO:0009150;purine ribonucleotide metabolic process;1.05360935984779e-06!GO:0000096;sulfur amino acid metabolic process;1.05617328922947e-06!GO:0019318;hexose metabolic process;1.14928733696998e-06!GO:0006399;tRNA metabolic process;1.16773772560453e-06!GO:0065002;intracellular protein transport across a membrane;1.25126572439511e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.27829688531278e-06!GO:0009144;purine nucleoside triphosphate metabolic process;1.27829688531278e-06!GO:0009142;nucleoside triphosphate biosynthetic process;1.3162800661331e-06!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.3162800661331e-06!GO:0009141;nucleoside triphosphate metabolic process;1.56172245325283e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.9036001273173e-06!GO:0004812;aminoacyl-tRNA ligase activity;1.9036001273173e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.9036001273173e-06!GO:0046034;ATP metabolic process;1.97933841534652e-06!GO:0008639;small protein conjugating enzyme activity;2.00740248380465e-06!GO:0005839;proteasome core complex (sensu Eukaryota);2.24129644455583e-06!GO:0006790;sulfur metabolic process;2.24757130730612e-06!GO:0045259;proton-transporting ATP synthase complex;2.36069680355388e-06!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;2.361602609657e-06!GO:0006006;glucose metabolic process;2.49511236025493e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.50347385615007e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.50347385615007e-06!GO:0050660;FAD binding;2.74928444067743e-06!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.78291768752508e-06!GO:0004842;ubiquitin-protein ligase activity;2.88237388101348e-06!GO:0006754;ATP biosynthetic process;2.91577690565435e-06!GO:0006753;nucleoside phosphate metabolic process;2.91577690565435e-06!GO:0043412;biopolymer modification;2.95720563858295e-06!GO:0032553;ribonucleotide binding;3.41853861644468e-06!GO:0032555;purine ribonucleotide binding;3.41853861644468e-06!GO:0043038;amino acid activation;3.41853861644468e-06!GO:0006418;tRNA aminoacylation for protein translation;3.41853861644468e-06!GO:0043039;tRNA aminoacylation;3.41853861644468e-06!GO:0006869;lipid transport;3.74220188027402e-06!GO:0009152;purine ribonucleotide biosynthetic process;4.46752064497265e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;5.91578120562639e-06!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;6.47411981202735e-06!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;6.47411981202735e-06!GO:0042254;ribosome biogenesis and assembly;6.48250287439601e-06!GO:0030170;pyridoxal phosphate binding;7.02188772363538e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;7.54750491317695e-06!GO:0015399;primary active transmembrane transporter activity;7.54750491317695e-06!GO:0005319;lipid transporter activity;7.54750491317695e-06!GO:0019787;small conjugating protein ligase activity;7.98674247286046e-06!GO:0006694;steroid biosynthetic process;8.49887448996287e-06!GO:0003712;transcription cofactor activity;8.80707366634891e-06!GO:0009069;serine family amino acid metabolic process;8.94522495594187e-06!GO:0016853;isomerase activity;9.40468090767541e-06!GO:0006259;DNA metabolic process;1.03990256891475e-05!GO:0004298;threonine endopeptidase activity;1.12749752719509e-05!GO:0005643;nuclear pore;1.16807714676813e-05!GO:0019395;fatty acid oxidation;1.17660651882809e-05!GO:0016469;proton-transporting two-sector ATPase complex;1.24832178286187e-05!GO:0042157;lipoprotein metabolic process;1.27528396212552e-05!GO:0005762;mitochondrial large ribosomal subunit;1.27933070466058e-05!GO:0000315;organellar large ribosomal subunit;1.27933070466058e-05!GO:0009074;aromatic amino acid family catabolic process;1.30319505006095e-05!GO:0008483;transaminase activity;1.3209884823824e-05!GO:0048475;coated membrane;1.34230558576739e-05!GO:0030117;membrane coat;1.34230558576739e-05!GO:0005524;ATP binding;1.34531422368895e-05!GO:0009719;response to endogenous stimulus;1.37627498936083e-05!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.4105091503939e-05!GO:0032559;adenyl ribonucleotide binding;1.49166893914735e-05!GO:0006725;aromatic compound metabolic process;1.54331782826247e-05!GO:0043069;negative regulation of programmed cell death;1.59376128535276e-05!GO:0006613;cotranslational protein targeting to membrane;1.66385753663198e-05!GO:0016769;transferase activity, transferring nitrogenous groups;1.81763673390345e-05!GO:0051287;NAD binding;1.83562761654446e-05!GO:0043066;negative regulation of apoptosis;1.93226725058463e-05!GO:0005788;endoplasmic reticulum lumen;2.17872607652938e-05!GO:0008654;phospholipid biosynthetic process;2.30448971466103e-05!GO:0000314;organellar small ribosomal subunit;2.54861161076866e-05!GO:0005763;mitochondrial small ribosomal subunit;2.54861161076866e-05!GO:0009117;nucleotide metabolic process;2.82754854314088e-05!GO:0006635;fatty acid beta-oxidation;2.82932257510315e-05!GO:0006979;response to oxidative stress;3.03168540818534e-05!GO:0032446;protein modification by small protein conjugation;3.08459371083469e-05!GO:0050657;nucleic acid transport;3.18945595291573e-05!GO:0051236;establishment of RNA localization;3.18945595291573e-05!GO:0050658;RNA transport;3.18945595291573e-05!GO:0051540;metal cluster binding;3.23886103859517e-05!GO:0051536;iron-sulfur cluster binding;3.23886103859517e-05!GO:0006464;protein modification process;3.43562738622822e-05!GO:0016881;acid-amino acid ligase activity;3.56213515856272e-05!GO:0006403;RNA localization;3.90803934414616e-05!GO:0019867;outer membrane;4.04822128650588e-05!GO:0016741;transferase activity, transferring one-carbon groups;4.32684097969874e-05!GO:0045454;cell redox homeostasis;4.32901430867168e-05!GO:0042981;regulation of apoptosis;4.44676257667308e-05!GO:0006612;protein targeting to membrane;4.45820876340435e-05!GO:0044438;microbody part;4.49373534019531e-05!GO:0044439;peroxisomal part;4.49373534019531e-05!GO:0022890;inorganic cation transmembrane transporter activity;5.08381236977848e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;5.21012609865095e-05!GO:0007005;mitochondrion organization and biogenesis;5.22001038955344e-05!GO:0031968;organelle outer membrane;5.22736078227388e-05!GO:0051246;regulation of protein metabolic process;5.25263973459539e-05!GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors;5.51633009726334e-05!GO:0051789;response to protein stimulus;5.51633009726334e-05!GO:0006986;response to unfolded protein;5.51633009726334e-05!GO:0043067;regulation of programmed cell death;5.95638626789251e-05!GO:0043492;ATPase activity, coupled to movement of substances;5.98840658074677e-05!GO:0046364;monosaccharide biosynthetic process;6.58927664855383e-05!GO:0046165;alcohol biosynthetic process;6.58927664855383e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;6.63533063799534e-05!GO:0016567;protein ubiquitination;6.7283737302165e-05!GO:0004386;helicase activity;7.04245582817627e-05!GO:0005770;late endosome;7.36300778400153e-05!GO:0006558;L-phenylalanine metabolic process;7.44228476267122e-05!GO:0006559;L-phenylalanine catabolic process;7.44228476267122e-05!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;8.03211103946939e-05!GO:0000097;sulfur amino acid biosynthetic process;8.08811539179764e-05!GO:0016746;transferase activity, transferring acyl groups;8.13409980096628e-05!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;8.38200964508123e-05!GO:0000151;ubiquitin ligase complex;8.45779586641671e-05!GO:0009064;glutamine family amino acid metabolic process;8.48320405007149e-05!GO:0016830;carbon-carbon lyase activity;8.48320405007149e-05!GO:0003995;acyl-CoA dehydrogenase activity;9.49028021095058e-05!GO:0008026;ATP-dependent helicase activity;9.68294276709077e-05!GO:0046870;cadmium ion binding;9.81598348832034e-05!GO:0043566;structure-specific DNA binding;0.000105486201159216!GO:0031903;microbody membrane;0.000111832454924338!GO:0005778;peroxisomal membrane;0.000111832454924338!GO:0043284;biopolymer biosynthetic process;0.000115433718359736!GO:0016747;transferase activity, transferring groups other than amino-acyl groups;0.000120744905053725!GO:0044431;Golgi apparatus part;0.000126309050854891!GO:0051539;4 iron, 4 sulfur cluster binding;0.000130679621831067!GO:0044440;endosomal part;0.000135331327983483!GO:0010008;endosome membrane;0.000135331327983483!GO:0005741;mitochondrial outer membrane;0.000140146707571717!GO:0044272;sulfur compound biosynthetic process;0.000149178022290818!GO:0030532;small nuclear ribonucleoprotein complex;0.000149178022290818!GO:0019319;hexose biosynthetic process;0.00015645879331936!GO:0043228;non-membrane-bound organelle;0.000160363185109508!GO:0043232;intracellular non-membrane-bound organelle;0.000160363185109508!GO:0030867;rough endoplasmic reticulum membrane;0.000174465917206864!GO:0006364;rRNA processing;0.00020396329457452!GO:0006778;porphyrin metabolic process;0.000212957638837797!GO:0033013;tetrapyrrole metabolic process;0.000212957638837797!GO:0008415;acyltransferase activity;0.00021356344771685!GO:0051028;mRNA transport;0.000216106147104109!GO:0005791;rough endoplasmic reticulum;0.000219507341161142!GO:0051384;response to glucocorticoid stimulus;0.000239817302141336!GO:0008168;methyltransferase activity;0.000246468297917179!GO:0051170;nuclear import;0.000279882171591609!GO:0042802;identical protein binding;0.000285176408182306!GO:0043021;ribonucleoprotein binding;0.000285946891148023!GO:0006953;acute-phase response;0.000290344917622242!GO:0006090;pyruvate metabolic process;0.000297660916772518!GO:0005798;Golgi-associated vesicle;0.000300285464397767!GO:0006525;arginine metabolic process;0.000301963933690375!GO:0016072;rRNA metabolic process;0.000308306775507203!GO:0006974;response to DNA damage stimulus;0.000356054019434451!GO:0006767;water-soluble vitamin metabolic process;0.000375127357124043!GO:0006606;protein import into nucleus;0.000379386922772299!GO:0031960;response to corticosteroid stimulus;0.000417211851056971!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000428025478995743!GO:0000245;spliceosome assembly;0.000431532615532785!GO:0009066;aspartate family amino acid metabolic process;0.000431532615532785!GO:0006094;gluconeogenesis;0.00047243796104133!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000490802214103089!GO:0046394;carboxylic acid biosynthetic process;0.000540677299347456!GO:0016053;organic acid biosynthetic process;0.000540677299347456!GO:0031988;membrane-bound vesicle;0.000540677299347456!GO:0016064;immunoglobulin mediated immune response;0.000548505687142977!GO:0008286;insulin receptor signaling pathway;0.000599268448429903!GO:0016779;nucleotidyltransferase activity;0.000607509626461136!GO:0006957;complement activation, alternative pathway;0.000622228334544996!GO:0006508;proteolysis;0.000647931749610676!GO:0002253;activation of immune response;0.000650916842432596!GO:0009112;nucleobase metabolic process;0.000656893572378!GO:0016645;oxidoreductase activity, acting on the CH-NH group of donors;0.000671948895525446!GO:0006749;glutathione metabolic process;0.000683908818159578!GO:0043687;post-translational protein modification;0.000686899250621816!GO:0006518;peptide metabolic process;0.000746742775217681!GO:0016051;carbohydrate biosynthetic process;0.000750104764832364!GO:0016023;cytoplasmic membrane-bound vesicle;0.000807688471067576!GO:0051920;peroxiredoxin activity;0.000829842754470397!GO:0015923;mannosidase activity;0.000846065604669902!GO:0019899;enzyme binding;0.000847682351399223!GO:0006916;anti-apoptosis;0.000869808193063227!GO:0051537;2 iron, 2 sulfur cluster binding;0.000880505345430411!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000880872417523499!GO:0009165;nucleotide biosynthetic process;0.000975126073816567!GO:0000139;Golgi membrane;0.00103379124359252!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00103379124359252!GO:0015002;heme-copper terminal oxidase activity;0.00103379124359252!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00103379124359252!GO:0004129;cytochrome-c oxidase activity;0.00103379124359252!GO:0043681;protein import into mitochondrion;0.00105133140493673!GO:0031982;vesicle;0.00113529195134714!GO:0009081;branched chain family amino acid metabolic process;0.00116221581658965!GO:0042168;heme metabolic process;0.00121067341010206!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00121067341010206!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00121067341010206!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00121067341010206!GO:0009309;amine biosynthetic process;0.00122727532025434!GO:0031324;negative regulation of cellular metabolic process;0.0012304238980821!GO:0016885;ligase activity, forming carbon-carbon bonds;0.00123518798891298!GO:0048471;perinuclear region of cytoplasm;0.00126103391251103!GO:0003724;RNA helicase activity;0.00128111114863556!GO:0019438;aromatic compound biosynthetic process;0.00138591160534656!GO:0019724;B cell mediated immunity;0.00147790815033757!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.0015196521412982!GO:0051716;cellular response to stimulus;0.00153252563381915!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.00157109792613875!GO:0006766;vitamin metabolic process;0.00161889196947175!GO:0031410;cytoplasmic vesicle;0.0016212944676746!GO:0030134;ER to Golgi transport vesicle;0.00171301255537846!GO:0016044;membrane organization and biogenesis;0.00174639889502079!GO:0003697;single-stranded DNA binding;0.00177798660913887!GO:0051659;maintenance of mitochondrion localization;0.00180400837209159!GO:0051657;maintenance of organelle localization;0.00180400837209159!GO:0006414;translational elongation;0.00183454178310183!GO:0051168;nuclear export;0.00185289622291811!GO:0003690;double-stranded DNA binding;0.00185289622291811!GO:0030658;transport vesicle membrane;0.00193377474312822!GO:0004300;enoyl-CoA hydratase activity;0.00197776906307162!GO:0030176;integral to endoplasmic reticulum membrane;0.00197776906307162!GO:0016564;transcription repressor activity;0.00198254006569615!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.00198912707509711!GO:0006366;transcription from RNA polymerase II promoter;0.00205761844792616!GO:0005579;membrane attack complex;0.00206969570327418!GO:0006650;glycerophospholipid metabolic process;0.00208187037456269!GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides;0.00209395745113824!GO:0031970;organelle envelope lumen;0.00216175934733053!GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen;0.0021883468761357!GO:0004029;aldehyde dehydrogenase (NAD) activity;0.00222994492847062!GO:0000050;urea cycle;0.00230428518369291!GO:0043603;amide metabolic process;0.00230428518369291!GO:0019627;urea metabolic process;0.00230428518369291!GO:0003714;transcription corepressor activity;0.00230428518369291!GO:0001889;liver development;0.00233222638459165!GO:0006081;aldehyde metabolic process;0.00233222638459165!GO:0006779;porphyrin biosynthetic process;0.00234461349792084!GO:0033014;tetrapyrrole biosynthetic process;0.00234461349792084!GO:0016568;chromatin modification;0.00238511706171008!GO:0033116;ER-Golgi intermediate compartment membrane;0.00247917008298735!GO:0016835;carbon-oxygen lyase activity;0.0025166305979326!GO:0009083;branched chain family amino acid catabolic process;0.00260121694480497!GO:0046474;glycerophospholipid biosynthetic process;0.00262412689595929!GO:0030127;COPII vesicle coat;0.00263710280264792!GO:0012507;ER to Golgi transport vesicle membrane;0.00263710280264792!GO:0003713;transcription coactivator activity;0.00264291613274504!GO:0008206;bile acid metabolic process;0.00268780687380362!GO:0015918;sterol transport;0.00281640884274089!GO:0030301;cholesterol transport;0.00281640884274089!GO:0006487;protein amino acid N-linked glycosylation;0.00282401206854481!GO:0016877;ligase activity, forming carbon-sulfur bonds;0.00284367297053183!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.00286976961780513!GO:0046983;protein dimerization activity;0.00289848000735271!GO:0006818;hydrogen transport;0.00289848000735271!GO:0048500;signal recognition particle;0.00289862691513779!GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds;0.00295938559578492!GO:0006720;isoprenoid metabolic process;0.00304562508360391!GO:0030133;transport vesicle;0.00312052253970249!GO:0005758;mitochondrial intermembrane space;0.00314412856488057!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00327940728682015!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00327940728682015!GO:0015036;disulfide oxidoreductase activity;0.00337235611850505!GO:0004364;glutathione transferase activity;0.00343665377325223!GO:0006281;DNA repair;0.00346970665526548!GO:0016831;carboxy-lyase activity;0.00348725552520787!GO:0006879;cellular iron ion homeostasis;0.00348725552520787!GO:0055072;iron ion homeostasis;0.00348725552520787!GO:0031326;regulation of cellular biosynthetic process;0.00351612635964322!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00354639707956469!GO:0004576;oligosaccharyl transferase activity;0.00362413478696334!GO:0010033;response to organic substance;0.00368012635275342!GO:0030139;endocytic vesicle;0.00374461111223132!GO:0016836;hydro-lyase activity;0.00375822259551417!GO:0044242;cellular lipid catabolic process;0.00375849686210605!GO:0008299;isoprenoid biosynthetic process;0.00398264200882663!GO:0015992;proton transport;0.00414665700406638!GO:0043623;cellular protein complex assembly;0.00419831318861586!GO:0016421;CoA carboxylase activity;0.00422029362106213!GO:0007040;lysosome organization and biogenesis;0.00424520226054356!GO:0009889;regulation of biosynthetic process;0.00430510597961398!GO:0046146;tetrahydrobiopterin metabolic process;0.00430510597961398!GO:0006402;mRNA catabolic process;0.00436079422536655!GO:0042559;pteridine and derivative biosynthetic process;0.00437769641222752!GO:0006572;tyrosine catabolic process;0.00444250732154732!GO:0016407;acetyltransferase activity;0.00470655955151922!GO:0006644;phospholipid metabolic process;0.00481413740991024!GO:0030660;Golgi-associated vesicle membrane;0.00487540725707775!GO:0045947;negative regulation of translational initiation;0.0050727947272203!GO:0007249;I-kappaB kinase/NF-kappaB cascade;0.00519628094843534!GO:0044271;nitrogen compound biosynthetic process;0.00521287900417158!GO:0042558;pteridine and derivative metabolic process;0.00523421880040576!GO:0046395;carboxylic acid catabolic process;0.00528058422044904!GO:0016054;organic acid catabolic process;0.00528058422044904!GO:0006555;methionine metabolic process;0.00529358540953518!GO:0009892;negative regulation of metabolic process;0.00539856057816811!GO:0042627;chylomicron;0.00539856057816811!GO:0006733;oxidoreduction coenzyme metabolic process;0.00544852245286679!GO:0004177;aminopeptidase activity;0.00544852245286679!GO:0019216;regulation of lipid metabolic process;0.00556073691755137!GO:0015924;mannosyl-oligosaccharide mannosidase activity;0.00560779170184245!GO:0033554;cellular response to stress;0.00568307860436509!GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor;0.00582950169518645!GO:0030569;chymotrypsin inhibitor activity;0.00601927117764222!GO:0006417;regulation of translation;0.00624598231932312!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00638800349114035!GO:0030132;clathrin coat of coated pit;0.00640941732720844!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0064554361575516!GO:0045047;protein targeting to ER;0.0064554361575516!GO:0016798;hydrolase activity, acting on glycosyl bonds;0.0064554361575516!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;0.00654402778089007!GO:0051427;hormone receptor binding;0.00655528079992632!GO:0008250;oligosaccharyl transferase complex;0.00665498633334584!GO:0003746;translation elongation factor activity;0.00673074846833051!GO:0006527;arginine catabolic process;0.00702121291279043!GO:0016408;C-acyltransferase activity;0.00703525539465589!GO:0006563;L-serine metabolic process;0.0070727724558415!GO:0031072;heat shock protein binding;0.00712883736684054!GO:0006626;protein targeting to mitochondrion;0.00722837093599954!GO:0005885;Arp2/3 protein complex;0.00743170266829833!GO:0004553;hydrolase activity, hydrolyzing O-glycosyl compounds;0.0076013697237036!GO:0048523;negative regulation of cellular process;0.00762977141588116!GO:0009225;nucleotide-sugar metabolic process;0.00763061839933573!GO:0009070;serine family amino acid biosynthetic process;0.00797530439657964!GO:0030663;COPI coated vesicle membrane;0.00814781834909129!GO:0030126;COPI vesicle coat;0.00814781834909129!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00820774675512789!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.00840038440035256!GO:0005905;coated pit;0.00869649962160678!GO:0005048;signal sequence binding;0.0087287182612265!GO:0008430;selenium binding;0.00884942435411178!GO:0046467;membrane lipid biosynthetic process;0.00886360277753548!GO:0046489;phosphoinositide biosynthetic process;0.0088875964056692!GO:0016859;cis-trans isomerase activity;0.0090909369245017!GO:0003729;mRNA binding;0.00938796699220051!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00941104573941892!GO:0016878;acid-thiol ligase activity;0.00954283494122634!GO:0016197;endosome transport;0.00975131108819764!GO:0042158;lipoprotein biosynthetic process;0.00987273403297575!GO:0030433;ER-associated protein catabolic process;0.00990695934178654!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.00990695934178654!GO:0003899;DNA-directed RNA polymerase activity;0.00999139660002466!GO:0008186;RNA-dependent ATPase activity;0.0100192402279819!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.0101654251754774!GO:0000062;acyl-CoA binding;0.0103189702135544!GO:0005769;early endosome;0.0103380550844974!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;0.0106406575879049!GO:0008312;7S RNA binding;0.010648664084405!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.0108238002259948!GO:0009374;biotin binding;0.0111438562960272!GO:0045786;negative regulation of progression through cell cycle;0.0113923710432212!GO:0007031;peroxisome organization and biogenesis;0.0113923710432212!GO:0006534;cysteine metabolic process;0.0113923710432212!GO:0035257;nuclear hormone receptor binding;0.0114393624145355!GO:0031668;cellular response to extracellular stimulus;0.0114393624145355!GO:0031252;leading edge;0.0116892567649583!GO:0006354;RNA elongation;0.0123841840169212!GO:0018196;peptidyl-asparagine modification;0.0124498649063582!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0124498649063582!GO:0006595;polyamine metabolic process;0.0125505560088419!GO:0006783;heme biosynthetic process;0.0125638183743923!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0126630597264207!GO:0003756;protein disulfide isomerase activity;0.0127220884500225!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0127220884500225!GO:0030880;RNA polymerase complex;0.0129545366807994!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0129812767552823!GO:0006206;pyrimidine base metabolic process;0.0133416665434135!GO:0006401;RNA catabolic process;0.0139672024619496!GO:0007033;vacuole organization and biogenesis;0.0139806761564868!GO:0016410;N-acyltransferase activity;0.014010800017652!GO:0010035;response to inorganic substance;0.0141815303372558!GO:0007006;mitochondrial membrane organization and biogenesis;0.0150864989530387!GO:0006658;phosphatidylserine metabolic process;0.01526405124961!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.01526405124961!GO:0008374;O-acyltransferase activity;0.015377116627427!GO:0016840;carbon-nitrogen lyase activity;0.015377116627427!GO:0006643;membrane lipid metabolic process;0.015377116627427!GO:0009067;aspartate family amino acid biosynthetic process;0.0154158325753344!GO:0009991;response to extracellular stimulus;0.0156352377917428!GO:0048519;negative regulation of biological process;0.0157220683512076!GO:0006325;establishment and/or maintenance of chromatin architecture;0.0159389046628961!GO:0006729;tetrahydrobiopterin biosynthetic process;0.0161762683398682!GO:0000049;tRNA binding;0.0163261816263352!GO:0031406;carboxylic acid binding;0.016513310595918!GO:0019843;rRNA binding;0.0165811637190518!GO:0008172;S-methyltransferase activity;0.0167500864035585!GO:0016709;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen;0.0168278412633929!GO:0006706;steroid catabolic process;0.0168637115857769!GO:0044275;cellular carbohydrate catabolic process;0.0170084825091038!GO:0042594;response to starvation;0.0170810354808069!GO:0042364;water-soluble vitamin biosynthetic process;0.0171922166739588!GO:0005977;glycogen metabolic process;0.0172386408141084!GO:0030145;manganese ion binding;0.0176445886317719!GO:0046904;calcium oxalate binding;0.0180135541860322!GO:0030568;plasmin inhibitor activity;0.0180135541860322!GO:0005667;transcription factor complex;0.0180703465353087!GO:0000287;magnesium ion binding;0.0181998744079316!GO:0045239;tricarboxylic acid cycle enzyme complex;0.0183263800669804!GO:0015682;ferric iron transport;0.0191194851922506!GO:0015091;ferric iron transmembrane transporter activity;0.0191194851922506!GO:0031643;positive regulation of myelination;0.0191194851922506!GO:0051252;regulation of RNA metabolic process;0.0194147945668446!GO:0004571;mannosyl-oligosaccharide 1,2-alpha-mannosidase activity;0.0194334242425769!GO:0043488;regulation of mRNA stability;0.0196133439722627!GO:0043487;regulation of RNA stability;0.0196133439722627!GO:0004448;isocitrate dehydrogenase activity;0.0196637156599084!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0199057995419762!GO:0015886;heme transport;0.0201425970754399!GO:0050327;testosterone 17-beta-dehydrogenase activity;0.0205352125297837!GO:0006007;glucose catabolic process;0.021060815053364!GO:0006544;glycine metabolic process;0.0210923480681467!GO:0016563;transcription activator activity;0.0212486414684217!GO:0050749;apolipoprotein E receptor binding;0.0212486414684217!GO:0048487;beta-tubulin binding;0.021661837764783!GO:0030125;clathrin vesicle coat;0.0217955494812908!GO:0030665;clathrin coated vesicle membrane;0.0217955494812908!GO:0007034;vacuolar transport;0.0221415222203129!GO:0005577;fibrinogen complex;0.0222496102343745!GO:0043094;metabolic compound salvage;0.0224704430542101!GO:0004004;ATP-dependent RNA helicase activity;0.0227459462971768!GO:0005774;vacuolar membrane;0.0230576502879811!GO:0031625;ubiquitin protein ligase binding;0.0230636607056768!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0232839349760425!GO:0003924;GTPase activity;0.0235962537855025!GO:0007596;blood coagulation;0.0237056044103974!GO:0015205;nucleobase transmembrane transporter activity;0.0238565793328108!GO:0050748;negative regulation of lipoprotein metabolic process;0.0245475287505048!GO:0006891;intra-Golgi vesicle-mediated transport;0.024558309887526!GO:0006611;protein export from nucleus;0.0250085005348878!GO:0007599;hemostasis;0.0250700359553695!GO:0030118;clathrin coat;0.0251108091283268!GO:0030151;molybdenum ion binding;0.0254647229730751!GO:0002449;lymphocyte mediated immunity;0.0258483587682271!GO:0006839;mitochondrial transport;0.0264343483222683!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.0269895812384424!GO:0000428;DNA-directed RNA polymerase complex;0.0269895812384424!GO:0015035;protein disulfide oxidoreductase activity;0.0275653747388386!GO:0006793;phosphorus metabolic process;0.0281787115727622!GO:0006796;phosphate metabolic process;0.0281787115727622!GO:0030137;COPI-coated vesicle;0.0286308044186483!GO:0008320;protein transmembrane transporter activity;0.0288133675736866!GO:0009086;methionine biosynthetic process;0.0288307986288451!GO:0005525;GTP binding;0.0288307986288451!GO:0030659;cytoplasmic vesicle membrane;0.0299516069329434!GO:0006633;fatty acid biosynthetic process;0.0299952003015306!GO:0051087;chaperone binding;0.0299952003015306!GO:0006984;ER-nuclear signaling pathway;0.0302164677209364!GO:0030503;regulation of cell redox homeostasis;0.0307641381698034!GO:0030518;steroid hormone receptor signaling pathway;0.0308304258207297!GO:0016624;oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor;0.0313834226703366!GO:0006959;humoral immune response;0.0314645158698!GO:0006323;DNA packaging;0.0315819708684053!GO:0046487;glyoxylate metabolic process;0.0318386124280265!GO:0051101;regulation of DNA binding;0.032004316790536!GO:0050811;GABA receptor binding;0.0325632427809038!GO:0005159;insulin-like growth factor receptor binding;0.0336709720515537!GO:0004372;glycine hydroxymethyltransferase activity;0.0337489254117846!GO:0006022;aminoglycan metabolic process;0.0337489254117846!GO:0050817;coagulation;0.0342393141280533!GO:0006073;glucan metabolic process;0.0342410822276425!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0355660748020976!GO:0007243;protein kinase cascade;0.036626230700108!GO:0042221;response to chemical stimulus;0.0366274143847963!GO:0006497;protein amino acid lipidation;0.0366274143847963!GO:0017166;vinculin binding;0.0367772336728741!GO:0009116;nucleoside metabolic process;0.0370952005528689!GO:0001666;response to hypoxia;0.03747361468647!GO:0030235;nitric-oxide synthase regulator activity;0.0375184757147257!GO:0005684;U2-dependent spliceosome;0.037626079086373!GO:0006642;triacylglycerol mobilization;0.0376372584669053!GO:0006526;arginine biosynthetic process;0.0382810522796675!GO:0002018;renin-angiotensin regulation of aldosterone production;0.0391409856105437!GO:0048143;astrocyte activation;0.0391409856105437!GO:0046622;positive regulation of organ growth;0.0391409856105437!GO:0031701;angiotensin receptor binding;0.0391409856105437!GO:0031703;type 2 angiotensin receptor binding;0.0391409856105437!GO:0045723;positive regulation of fatty acid biosynthetic process;0.0391409856105437!GO:0001999;renal response to blood flow during renin-angiotensin regulation of systemic arterial blood pressure;0.0391409856105437!GO:0042756;drinking behavior;0.0391409856105437!GO:0002019;angiotensin mediated regulation of renal output;0.0391409856105437!GO:0031702;type 1 angiotensin receptor binding;0.0391409856105437!GO:0001998;angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure;0.0391409856105437!GO:0031327;negative regulation of cellular biosynthetic process;0.0391409856105437!GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen;0.0391523082662742!GO:0045540;regulation of cholesterol biosynthetic process;0.0395097246856815!GO:0000041;transition metal ion transport;0.0395097246856815!GO:0016646;oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor;0.0395660419348036!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.0398424944130094!GO:0043022;ribosome binding;0.0399175664981254!GO:0031669;cellular response to nutrient levels;0.0399402405837833!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0400269287383429!GO:0051726;regulation of cell cycle;0.0400887959728964!GO:0008139;nuclear localization sequence binding;0.0406583334895404!GO:0044264;cellular polysaccharide metabolic process;0.0408037499404432!GO:0008033;tRNA processing;0.0408037499404432!GO:0030508;thiol-disulfide exchange intermediate activity;0.0408157816999963!GO:0001887;selenium metabolic process;0.0417836840365415!GO:0044437;vacuolar part;0.0424857303283139!GO:0005784;translocon complex;0.0426400686052822!GO:0031647;regulation of protein stability;0.0434243965431232!GO:0006013;mannose metabolic process;0.0434243965431232!GO:0019321;pentose metabolic process;0.0438388230818478!GO:0000074;regulation of progression through cell cycle;0.0455553652221994!GO:0003711;transcription elongation regulator activity;0.0457312585262175!GO:0003812;alternative-complement-pathway C3/C5 convertase activity;0.046694709609892!GO:0046112;nucleobase biosynthetic process;0.0474024222731824!GO:0032287;myelin maintenance in the peripheral nervous system;0.0474024222731824!GO:0032838;cell projection cytoplasm;0.0474024222731824!GO:0033081;regulation of T cell differentiation in the thymus;0.0474024222731824!GO:0043217;myelin maintenance;0.0474024222731824!GO:0060087;relaxation of vascular smooth muscle;0.0474024222731824!GO:0032839;dendrite cytoplasm;0.0474024222731824!GO:0009267;cellular response to starvation;0.0474467956612049!GO:0031667;response to nutrient levels;0.0475382751745498!GO:0008383;manganese superoxide dismutase activity;0.0481831082248764!GO:0001315;age-dependent response to reactive oxygen species;0.0481831082248764!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0491202140886656!GO:0010257;NADH dehydrogenase complex assembly;0.0491202140886656!GO:0033108;mitochondrial respiratory chain complex assembly;0.0491202140886656!GO:0006383;transcription from RNA polymerase III promoter;0.0496338938379861!GO:0006897;endocytosis;0.049777598762155!GO:0010324;membrane invagination;0.049777598762155!GO:0016481;negative regulation of transcription;0.0498063680074775 | |||
|sample_id=11523 | |||
|sample_note= | |||
|sample_sex= | |||
|sample_species=Human (Homo sapiens) | |||
|sample_strain= | |||
|sample_tissue=liver | |||
|top_motifs=HNF4A_NR2F1,2:8.12072270132;HNF1A:7.49141154743;FOXA2:6.65191124675;NR6A1:5.70561253248;RXR{A,B,G}_{NR1H2,PPAR}dimers:5.19476596438;AR:3.20481073147;FOX{F1,F2,J1}:2.96430279982;EVI1:2.86839236306;STAT2,4,6:2.8438520855;CUX2:2.81594298239;BPTF:2.4403694026;FOXD3:2.34736039494;ALX4:2.25161724029;NR1H4:2.2181446487;ARID5B:1.94108585384;POU6F1:1.91635098128;ADNP_IRX_SIX_ZHX:1.8788126578;NKX2-1,4:1.86335404525;DBP:1.70138799043;FOX{D1,D2}:1.63719891384;ONECUT1,2:1.6273328578;PAX1,9:1.60739106029;NFE2L1:1.58543833265;T:1.57228999716;MTF1:1.47197001921;GLI1..3:1.4581282146;NFIL3:1.34717453417;HOX{A4,D4}:1.34646497847;PAX4:1.33355316235;FOXM1:1.31885434621;MYOD1:1.26065914093;FOXP3:1.2602142333;ZBTB16:1.17745538921;RXRA_VDR{dimer}:1.11472283783;GATA6:1.09949309862;HLF:1.08562170218;RBPJ:1.02140407995;PPARG:0.978409557981;SNAI1..3:0.93501986754;PDX1:0.911002854432;TLX2:0.907654085367;CEBPA,B_DDIT3:0.901257497817;FOXQ1:0.872703887618;FOX{I1,J2}:0.86233519081;TAL1_TCF{3,4,12}:0.846685921903;FOXL1:0.758444866099;HOXA9_MEIS1:0.729533569091;bHLH_family:0.662518827137;ZEB1:0.654767954875;PBX1:0.645705867661;IRF7:0.628588818926;PAX3,7:0.608843625731;RXR{A,B,G}:0.558230428494;EN1,2:0.501332362582;HMGA1,2:0.482529073699;ATF6:0.451874557815;LMO2:0.440252297227;UFEwm:0.394030643906;YY1:0.390955493033;NKX3-2:0.382319360579;NR5A1,2:0.362775730058;PAX6:0.360885467685;FOXP1:0.27395058206;TBP:0.214362750756;AIRE:0.209114484077;EP300:0.186105111343;STAT1,3:0.181030199884;TEF:0.139064771299;HIF1A:0.0682531974781;HOX{A5,B5}:0.053371298188;TFCP2:0.0433540547179;CRX:0.0285428819149;TGIF1:0.00469485899234;GFI1:-0.0404189135356;GCM1,2:-0.0457396906444;CDX1,2,4:-0.0720363821232;NHLH1,2:-0.0942601656517;ALX1:-0.101081608799;NFIX:-0.115185032388;MYFfamily:-0.120955938121;HIC1:-0.127617229285;ZNF423:-0.182655379046;IKZF2:-0.188057746299;PAX2:-0.200757149167;VSX1,2:-0.201605380576;TLX1..3_NFIC{dimer}:-0.21582310323;SMAD1..7,9:-0.266525678239;SREBF1,2:-0.269497902651;DMAP1_NCOR{1,2}_SMARC:-0.275578949225;MED-1{core}:-0.27854064602;IRF1,2:-0.345725374079;RORA:-0.345821936028;KLF4:-0.348944036037;ATF5_CREB3:-0.382825610489;NKX2-2,8:-0.385768100034;MAFB:-0.40719899319;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.443134750186;HAND1,2:-0.451130184618;MTE{core}:-0.490941131283;NFY{A,B,C}:-0.506032611087;FOXN1:-0.519385082965;STAT5{A,B}:-0.519631523398;NFKB1_REL_RELA:-0.520139218415;REST:-0.590089418315;OCT4_SOX2{dimer}:-0.60581225104;ZNF143:-0.607961169918;TOPORS:-0.614540316953;ELF1,2,4:-0.619474702967;NFE2:-0.642303302952;PAX5:-0.686671205154;NR3C1:-0.690484303156;SP1:-0.691313567047;GZF1:-0.712143394288;MYBL2:-0.715904107543;IKZF1:-0.740868068346;SOX{8,9,10}:-0.749441421121;SOX5:-0.773812993931;SPI1:-0.788978520345;MEF2{A,B,C,D}:-0.803647957541;SOX17:-0.809475266558;LHX3,4:-0.811849467105;FOXO1,3,4:-0.814574815084;EBF1:-0.859888244805;BREu{core}:-0.863060273586;PITX1..3:-0.899261509122;TP53:-0.900976702992;RUNX1..3:-0.907113345515;ZFP161:-0.920011973614;EGR1..3:-0.921974392031;TBX4,5:-0.923719553004;SPIB:-0.944923545896;HES1:-0.946367130835;ELK1,4_GABP{A,B1}:-0.948419516336;MAZ:-0.981453046392;POU1F1:-0.993762036601;BACH2:-1.01883114491;NRF1:-1.03468832774;ZNF238:-1.05414285271;FOS_FOS{B,L1}_JUN{B,D}:-1.05604840296;ETS1,2:-1.06392579139;GTF2I:-1.0697025173;TFAP4:-1.07320772182;FOSL2:-1.07856297346;CREB1:-1.1108648681;NFATC1..3:-1.1150402525;RFX2..5_RFXANK_RFXAP:-1.12758334537;LEF1_TCF7_TCF7L1,2:-1.16732342251;POU3F1..4:-1.17628539885;ESR1:-1.18572693465;HOX{A6,A7,B6,B7}:-1.19014165194;E2F1..5:-1.19225520695;TEAD1:-1.19811352603;GATA4:-1.21394199555;PATZ1:-1.22000819585;TFAP2{A,C}:-1.23517847606;NFE2L2:-1.24176547981;GFI1B:-1.26421177023;HMX1:-1.27619367876;POU2F1..3:-1.29429005877;HSF1,2:-1.30623816474;NKX2-3_NKX2-5:-1.31232843602;HBP1_HMGB_SSRP1_UBTF:-1.3264808975;RFX1:-1.3322820716;RREB1:-1.33731585789;ESRRA:-1.3547221655;ATF4:-1.37665944789;ZIC1..3:-1.38715165179;TFAP2B:-1.41832968832;AHR_ARNT_ARNT2:-1.41905301524;ZBTB6:-1.44115275753;PRRX1,2:-1.57333899237;GTF2A1,2:-1.6252754814;SRF:-1.64337162861;MYB:-1.64670064897;JUN:-1.70884943071;SPZ1:-1.72432518345;PRDM1:-1.77967960846;NANOG{mouse}:-1.83539012139;NKX3-1:-1.86873010188;MZF1:-1.91007522003;NKX6-1,2:-1.99863511123;ATF2:-2.061727521;ZNF148:-2.124956038;ZNF384:-2.24069569309;SOX2:-2.26257551096;POU5F1:-2.27341965474;NANOG:-2.36753927731;CDC5L:-2.38536464987;PAX8:-2.41746000554;XBP1:-2.4307148547;XCPE1{core}:-2.47552143979;TFDP1:-2.54602133789 | |||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11523-119I2;search_select_hide=table117:FF:11523-119I2 | |||
}} | }} | ||
Latest revision as of 18:06, 4 June 2020
| Name: | Hepatocyte, donor1 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs12340 |
| Sample type: | primary cells |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13 |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| RNA-Seq Accession numbers | ||||||||||||||||||||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12340
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12340
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.0235 |
| 10 | 10 | 0.119 |
| 100 | 100 | 0.176 |
| 101 | 101 | 0.853 |
| 102 | 102 | 0.209 |
| 103 | 103 | 0.0436 |
| 104 | 104 | 0.875 |
| 105 | 105 | 0.367 |
| 106 | 106 | 0.0422 |
| 107 | 107 | 0.0426 |
| 108 | 108 | 0.338 |
| 109 | 109 | 0.202 |
| 11 | 11 | 0.172 |
| 110 | 110 | 0.152 |
| 111 | 111 | 0.132 |
| 112 | 112 | 0.0219 |
| 113 | 113 | 0.266 |
| 114 | 114 | 0.0213 |
| 115 | 115 | 0.648 |
| 116 | 116 | 0.303 |
| 117 | 117 | 0.238 |
| 118 | 118 | 0.209 |
| 119 | 119 | 0.0195 |
| 12 | 12 | 0.463 |
| 120 | 120 | 0.998 |
| 121 | 121 | 0.342 |
| 122 | 122 | 0.579 |
| 123 | 123 | 0.755 |
| 124 | 124 | 0.0774 |
| 125 | 125 | 0.56 |
| 126 | 126 | 0.105 |
| 127 | 127 | 0.557 |
| 128 | 128 | 0.129 |
| 129 | 129 | 0.0954 |
| 13 | 13 | 0.0748 |
| 130 | 130 | 0.019 |
| 131 | 131 | 0.714 |
| 132 | 132 | 0.583 |
| 133 | 133 | 0.513 |
| 134 | 134 | 0.576 |
| 135 | 135 | 0.847 |
| 136 | 136 | 0.889 |
| 137 | 137 | 0.35 |
| 138 | 138 | 0.281 |
| 139 | 139 | 0.692 |
| 14 | 14 | 0.674 |
| 140 | 140 | 0.107 |
| 141 | 141 | 0.0332 |
| 142 | 142 | 0.278 |
| 143 | 143 | 0.037 |
| 144 | 144 | 0.793 |
| 145 | 145 | 0.351 |
| 146 | 146 | 0.123 |
| 147 | 147 | 0.897 |
| 148 | 148 | 0.0699 |
| 149 | 149 | 0.0678 |
| 15 | 15 | 0.125 |
| 150 | 150 | 0.628 |
| 151 | 151 | 0.272 |
| 152 | 152 | 0.643 |
| 153 | 153 | 0.701 |
| 154 | 154 | 0.594 |
| 155 | 155 | 0.0439 |
| 156 | 156 | 0.695 |
| 157 | 157 | 0.791 |
| 158 | 158 | 0.995 |
| 159 | 159 | 0.744 |
| 16 | 16 | 0.174 |
| 160 | 160 | 0.135 |
| 161 | 161 | 0.395 |
| 162 | 162 | 0.634 |
| 163 | 163 | 0.654 |
| 164 | 164 | 0.111 |
| 165 | 165 | 0.0023 |
| 166 | 166 | 0.878 |
| 167 | 167 | 0.0182 |
| 168 | 168 | 0.745 |
| 169 | 169 | 3.96185e-4 |
| 17 | 17 | 0.32 |
| 18 | 18 | 0.693 |
| 19 | 19 | 0.0514 |
| 2 | 2 | 0.684 |
| 20 | 20 | 0.735 |
| 21 | 21 | 0.596 |
| 22 | 22 | 0.212 |
| 23 | 23 | 0.26 |
| 24 | 24 | 0.881 |
| 25 | 25 | 0.977 |
| 26 | 26 | 0.0352 |
| 27 | 27 | 0.434 |
| 28 | 28 | 0.75 |
| 29 | 29 | 0.176 |
| 3 | 3 | 0.168 |
| 30 | 30 | 0.875 |
| 31 | 31 | 0.387 |
| 32 | 32 | 0.463 |
| 33 | 33 | 0.4 |
| 34 | 34 | 0.91 |
| 35 | 35 | 0.0815 |
| 36 | 36 | 0.0761 |
| 37 | 37 | 0.249 |
| 38 | 38 | 0.315 |
| 39 | 39 | 0.386 |
| 4 | 4 | 0.497 |
| 40 | 40 | 0.0861 |
| 41 | 41 | 0.398 |
| 42 | 42 | 0.374 |
| 43 | 43 | 0.161 |
| 44 | 44 | 0.00219 |
| 45 | 45 | 0.591 |
| 46 | 46 | 0.106 |
| 47 | 47 | 0.218 |
| 48 | 48 | 0.239 |
| 49 | 49 | 0.161 |
| 5 | 5 | 0.293 |
| 50 | 50 | 0.698 |
| 51 | 51 | 0.733 |
| 52 | 52 | 0.19 |
| 53 | 53 | 0.956 |
| 54 | 54 | 0.556 |
| 55 | 55 | 0.245 |
| 56 | 56 | 0.358 |
| 57 | 57 | 0.484 |
| 58 | 58 | 0.35 |
| 59 | 59 | 0.17 |
| 6 | 6 | 0.703 |
| 60 | 60 | 0.0619 |
| 61 | 61 | 0.617 |
| 62 | 62 | 0.198 |
| 63 | 63 | 0.129 |
| 64 | 64 | 0.317 |
| 65 | 65 | 0.178 |
| 66 | 66 | 0.283 |
| 67 | 67 | 0.0925 |
| 68 | 68 | 0.717 |
| 69 | 69 | 0.872 |
| 7 | 7 | 0.111 |
| 70 | 70 | 0.0808 |
| 71 | 71 | 0.0501 |
| 72 | 72 | 0.495 |
| 73 | 73 | 0.417 |
| 74 | 74 | 0.692 |
| 75 | 75 | 0.131 |
| 76 | 76 | 0.984 |
| 77 | 77 | 0.067 |
| 78 | 78 | 0.0472 |
| 79 | 79 | 0.629 |
| 8 | 8 | 0.0374 |
| 80 | 80 | 0.562 |
| 81 | 81 | 0.298 |
| 82 | 82 | 0.188 |
| 83 | 83 | 0.435 |
| 84 | 84 | 0.397 |
| 85 | 85 | 0.0359 |
| 86 | 86 | 0.41 |
| 87 | 87 | 0.863 |
| 88 | 88 | 0.424 |
| 89 | 89 | 0.0665 |
| 9 | 9 | 0.873 |
| 90 | 90 | 0.129 |
| 91 | 91 | 0.101 |
| 92 | 92 | 0.185 |
| 93 | 93 | 0.427 |
| 94 | 94 | 0.894 |
| 95 | 95 | 0.813 |
| 96 | 96 | 0.171 |
| 97 | 97 | 0.341 |
| 98 | 98 | 0.258 |
| 99 | 99 | 0.124 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12340
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000078 human hepatocyte sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0002371 (somatic cell)
0000181 (metabolising cell)
0000417 (endopolyploid cell)
0000668 (parenchymal cell)
0000412 (polyploid cell)
0000255 (eukaryotic cell)
0000182 (hepatocyte)
UBERON: Anatomy
0000468 (multi-cellular organism)
0002107 (liver)
0002100 (trunk)
0001007 (digestive system)
0004119 (endoderm-derived structure)
0000062 (organ)
0000475 (organism subdivision)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0009569 (subdivision of trunk)
0002368 (endocrine gland)
0005177 (trunk region element)
0002365 (exocrine gland)
0005172 (abdomen element)
0006925 (digestive gland)
0002530 (gland)
0010317 (germ layer / neural crest derived structure)
0005173 (abdominal segment element)
0002417 (abdominal segment of trunk)
0000949 (endocrine system)
0002330 (exocrine system)
0000916 (abdomen)
0002423 (hepatobiliary system)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000002 (in vivo cell sample)
0000101 (sample by species)
0000001 (sample)
0000078 (human hepatocyte sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000134 (mesenchymal cell)
CL:0000223 (endodermal cell)
