FFCP PHASE1:Hg19::chr11:64107705..64107718,+: Difference between revisions
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{{FFCP | {{FFCP|DPIdataset=robustDPI|EntrezGene=283234|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=gencodeV16_protein_coding|HGNC=26757|TSSclassifier=S|UniProt=A6NC98|association_with_transcript=10bp_to_ENST00000356786,ENST00000463837,uc001nzy.2,uc009ypo.1_5end|coexpression_cluster_id=C57|description=CAGE_peak_2_at_CCDC88B_5end|id=chr11:64107705..64107718,+|ontology_enrichment_celltype=CL:0000037!1.30e-88!172;CL:0000566!1.30e-88!172;CL:0000988!1.28e-84!182;CL:0002032!2.31e-83!165;CL:0000837!2.31e-83!165;CL:0000738!6.53e-79!140;CL:0002031!6.02e-64!124;CL:0002087!1.83e-62!119;CL:0000763!5.54e-43!112;CL:0000049!5.54e-43!112;CL:0000542!3.18e-36!53;CL:0000051!3.18e-36!53;CL:0000838!7.02e-36!52;CL:0000766!7.45e-32!76;CL:0000557!2.29e-27!71;CL:0002057!4.84e-26!42;CL:0000839!1.95e-25!70;CL:0002009!1.56e-24!65;CL:0000860!3.66e-23!45;CL:0002194!4.77e-23!63;CL:0000576!4.77e-23!63;CL:0000040!4.77e-23!63;CL:0000559!4.77e-23!63;CL:0000945!4.28e-18!24;CL:0000826!4.28e-18!24;CL:0000084!5.12e-16!25;CL:0000827!5.12e-16!25;CL:0000791!2.20e-14!18;CL:0000789!2.20e-14!18;CL:0002420!2.20e-14!18;CL:0002419!2.20e-14!18;CL:0000790!2.20e-14!18;CL:0000134!2.39e-14!358;CL:0002320!3.12e-13!365;CL:0000236!4.77e-12!14;CL:0000625!1.07e-09!11;CL:0000219!1.76e-09!390;CL:0000094!5.20e-09!8;CL:0002393!1.64e-07!9;CL:0002397!1.64e-07!9;CL:0000451!3.56e-07!10;CL:0000081!5.79e-07!11|ontology_enrichment_celltype_v019=CL:0000542;1.39e-25;53!CL:0000860;1.01e-23;33!CL:0002057;1.01e-23;33!CL:0002087;1.63e-22;104!CL:0000945;2.30e-20;24!CL:0000576;4.23e-20;48!CL:0000738;9.46e-20;136!CL:0000084;9.76e-20;25!CL:0000791;1.28e-18;18!CL:0000789;1.28e-18;18!CL:0002419;1.28e-18;18!CL:0000473;9.44e-17;39!CL:0000234;9.44e-17;39!CL:0000766;2.71e-16;69!CL:0000988;1.11e-15;177!CL:0000236;2.39e-13;13!CL:0000763;1.75e-12;100!CL:0000625;1.87e-12;11!CL:0000094;1.54e-11;8!CL:0000081;3.00e-09;11!CL:0000451;4.40e-09;10!CL:0000219;4.84e-09;193!CL:0000990;4.42e-08;8!CL:0002393;1.57e-07;6!CL:0002397;1.57e-07;6!CL:0000624;4.22e-07;6|ontology_enrichment_celltype_v019_2=CL:0000037,2.86e-100,168;CL:0000988,9.43e-98,177;CL:0000738,6.07e-97,136;CL:0002032,8.40e-95,161;CL:0000837,8.40e-95,161;CL:0002087,9.72e-77,115;CL:0002031,7.49e-75,120;CL:0000763,8.40e-47,108;CL:0000049,8.40e-47,108;CL:0000542,1.47e-43,53;CL:0000051,1.47e-43,53;CL:0000838,4.41e-43,52;CL:0000766,8.28e-39,72;CL:0000860,2.51e-34,42;CL:0002057,2.51e-34,42;CL:0000557,6.91e-33,67;CL:0002009,2.75e-30,61;CL:0000473,1.27e-29,48;CL:0000234,1.27e-29,48;CL:0000839,2.11e-28,66;CL:0002194,2.61e-28,59;CL:0000576,2.61e-28,59;CL:0000040,2.61e-28,59;CL:0000559,2.61e-28,59;CL:0000134,7.19e-26,354;CL:0002320,1.31e-24,361;CL:0000945,1.49e-20,24;CL:0000826,1.49e-20,24;CL:0000219,3.24e-20,386;CL:0000084,1.11e-19,25;CL:0000827,1.11e-19,25;CL:0000791,1.05e-18,18;CL:0000789,1.05e-18,18;CL:0002420,1.05e-18,18;CL:0002419,1.05e-18,18;CL:0000790,1.05e-18,18;CL:0000048,5.64e-15,427;CL:0000034,2.25e-14,441;CL:0000723,2.87e-14,433;CL:0000236,5.97e-14,14;CL:0000625,1.95e-12,11;CL:0000094,1.61e-11,8;CL:0002393,1.60e-09,9;CL:0002397,1.60e-09,9;CL:0000081,3.36e-09,11;CL:0000451,4.51e-09,10;CL:0000990,4.81e-08,8;CL:0000624,2.55e-07,6|ontology_enrichment_development_v019=CL:0000051;1.39e-25;53!CL:0002057;1.63e-24;42!CL:0000790;1.28e-18;18!CL:0000049;3.32e-13;108|ontology_enrichment_disease=DOID:2531!3.62e-14!51;DOID:0060083!3.62e-14!51;DOID:1240!3.37e-11!39;DOID:8692!3.65e-08!31|ontology_enrichment_disease_v019=DOID:2531;1.81e-07;51!DOID:0060083;1.81e-07;51|ontology_enrichment_disease_v019_2=DOID:2531,5.01e-11,51;DOID:0060083,5.01e-11,51;DOID:1240,8.86e-08,39|ontology_enrichment_uberon=UBERON:0002390!6.72e-39!102;UBERON:0003061!6.72e-39!102;UBERON:0002193!5.70e-35!112;UBERON:0002371!8.38e-24!80;UBERON:0001474!1.47e-20!86;UBERON:0002405!7.61e-17!115;UBERON:0004765!6.22e-15!101;UBERON:0001434!6.22e-15!101;UBERON:0000178!1.06e-12!15;UBERON:0000179!1.06e-12!15;UBERON:0000463!1.06e-12!15;UBERON:0002384!9.62e-12!375;UBERON:0007023!1.69e-11!115;UBERON:0003081!1.84e-07!216|ontology_enrichment_uberon_v019=UBERON:0000178;1.18e-16;15!UBERON:0000179;1.18e-16;15!UBERON:0000463;1.18e-16;15!UBERON:0002390;1.41e-12;32!UBERON:0002193;2.46e-07;42|ontology_enrichment_uberon_v019_2=UBERON:0002390,2.52e-48,98;UBERON:0003061,2.52e-48,98;UBERON:0002193,1.76e-44,108;UBERON:0002405,1.06e-30,93;UBERON:0002371,2.04e-28,76;UBERON:0001474,4.66e-25,82;UBERON:0002384,6.72e-23,371;UBERON:0004765,2.61e-21,90;UBERON:0001434,1.59e-17,100;UBERON:0000178,1.88e-16,15;UBERON:0000179,1.88e-16,15;UBERON:0000463,1.88e-16,15;UBERON:0003081,5.39e-12,203;UBERON:0004177,3.48e-07,7;UBERON:0005057,3.48e-07,7|phase1_expression=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3.43860325865781,3.11982239909794,3.30585281517453,7.08055698328027,8.06041736004147,5.72819656269481,0,0,0,2.71135202031056,3.41206157969812,0.293600439334847,9.41792194504192,7.42014455639524,9.98250005292918,1.79132379391939,0.32389366601898,0.257575567634187,2.90796477559129,1.13362783106643,2.66842467306598,2.55671940596253,1.6446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| ||
|DPIdataset=robustDPI | |||
|EntrezGene=283234 | |||
|GencodeV16b_All_Build2_RSEM10_CPAT_consensus=gencodeV16_protein_coding | |||
|HGNC=26757 | |||
|TSSclassifier=S | |||
|UniProt=A6NC98 | |||
|association_with_transcript=10bp_to_ENST00000356786,ENST00000463837,uc001nzy.2,uc009ypo.1_5end | |||
|coexpression_cluster_id=C57 | |||
|description=CAGE_peak_2_at_CCDC88B_5end | |||
|id=chr11:64107705..64107718,+ | |||
|ontology_enrichment_celltype=CL:0000037!1.30e-88!172;CL:0000566!1.30e-88!172;CL:0000988!1.28e-84!182;CL:0002032!2.31e-83!165;CL:0000837!2.31e-83!165;CL:0000738!6.53e-79!140;CL:0002031!6.02e-64!124;CL:0002087!1.83e-62!119;CL:0000763!5.54e-43!112;CL:0000049!5.54e-43!112;CL:0000542!3.18e-36!53;CL:0000051!3.18e-36!53;CL:0000838!7.02e-36!52;CL:0000766!7.45e-32!76;CL:0000557!2.29e-27!71;CL:0002057!4.84e-26!42;CL:0000839!1.95e-25!70;CL:0002009!1.56e-24!65;CL:0000860!3.66e-23!45;CL:0002194!4.77e-23!63;CL:0000576!4.77e-23!63;CL:0000040!4.77e-23!63;CL:0000559!4.77e-23!63;CL:0000945!4.28e-18!24;CL:0000826!4.28e-18!24;CL:0000084!5.12e-16!25;CL:0000827!5.12e-16!25;CL:0000791!2.20e-14!18;CL:0000789!2.20e-14!18;CL:0002420!2.20e-14!18;CL:0002419!2.20e-14!18;CL:0000790!2.20e-14!18;CL:0000134!2.39e-14!358;CL:0002320!3.12e-13!365;CL:0000236!4.77e-12!14;CL:0000625!1.07e-09!11;CL:0000219!1.76e-09!390;CL:0000094!5.20e-09!8;CL:0002393!1.64e-07!9;CL:0002397!1.64e-07!9;CL:0000451!3.56e-07!10;CL:0000081!5.79e-07!11 | |||
|ontology_enrichment_celltype_v019=CL:0000542;1.39e-25;53!CL:0000860;1.01e-23;33!CL:0002057;1.01e-23;33!CL:0002087;1.63e-22;104!CL:0000945;2.30e-20;24!CL:0000576;4.23e-20;48!CL:0000738;9.46e-20;136!CL:0000084;9.76e-20;25!CL:0000791;1.28e-18;18!CL:0000789;1.28e-18;18!CL:0002419;1.28e-18;18!CL:0000473;9.44e-17;39!CL:0000234;9.44e-17;39!CL:0000766;2.71e-16;69!CL:0000988;1.11e-15;177!CL:0000236;2.39e-13;13!CL:0000763;1.75e-12;100!CL:0000625;1.87e-12;11!CL:0000094;1.54e-11;8!CL:0000081;3.00e-09;11!CL:0000451;4.40e-09;10!CL:0000219;4.84e-09;193!CL:0000990;4.42e-08;8!CL:0002393;1.57e-07;6!CL:0002397;1.57e-07;6!CL:0000624;4.22e-07;6 | |||
|ontology_enrichment_celltype_v019_2=CL:0000037,2.86e-100,168;CL:0000988,9.43e-98,177;CL:0000738,6.07e-97,136;CL:0002032,8.40e-95,161;CL:0000837,8.40e-95,161;CL:0002087,9.72e-77,115;CL:0002031,7.49e-75,120;CL:0000763,8.40e-47,108;CL:0000049,8.40e-47,108;CL:0000542,1.47e-43,53;CL:0000051,1.47e-43,53;CL:0000838,4.41e-43,52;CL:0000766,8.28e-39,72;CL:0000860,2.51e-34,42;CL:0002057,2.51e-34,42;CL:0000557,6.91e-33,67;CL:0002009,2.75e-30,61;CL:0000473,1.27e-29,48;CL:0000234,1.27e-29,48;CL:0000839,2.11e-28,66;CL:0002194,2.61e-28,59;CL:0000576,2.61e-28,59;CL:0000040,2.61e-28,59;CL:0000559,2.61e-28,59;CL:0000134,7.19e-26,354;CL:0002320,1.31e-24,361;CL:0000945,1.49e-20,24;CL:0000826,1.49e-20,24;CL:0000219,3.24e-20,386;CL:0000084,1.11e-19,25;CL:0000827,1.11e-19,25;CL:0000791,1.05e-18,18;CL:0000789,1.05e-18,18;CL:0002420,1.05e-18,18;CL:0002419,1.05e-18,18;CL:0000790,1.05e-18,18;CL:0000048,5.64e-15,427;CL:0000034,2.25e-14,441;CL:0000723,2.87e-14,433;CL:0000236,5.97e-14,14;CL:0000625,1.95e-12,11;CL:0000094,1.61e-11,8;CL:0002393,1.60e-09,9;CL:0002397,1.60e-09,9;CL:0000081,3.36e-09,11;CL:0000451,4.51e-09,10;CL:0000990,4.81e-08,8;CL:0000624,2.55e-07,6 | |||
|ontology_enrichment_development_v019=CL:0000051;1.39e-25;53!CL:0002057;1.63e-24;42!CL:0000790;1.28e-18;18!CL:0000049;3.32e-13;108 | |||
|ontology_enrichment_disease=DOID:2531!3.62e-14!51;DOID:0060083!3.62e-14!51;DOID:1240!3.37e-11!39;DOID:8692!3.65e-08!31 | |||
|ontology_enrichment_disease_v019=DOID:2531;1.81e-07;51!DOID:0060083;1.81e-07;51 | |||
|ontology_enrichment_disease_v019_2=DOID:2531,5.01e-11,51;DOID:0060083,5.01e-11,51;DOID:1240,8.86e-08,39 | |||
|ontology_enrichment_uberon=UBERON:0002390!6.72e-39!102;UBERON:0003061!6.72e-39!102;UBERON:0002193!5.70e-35!112;UBERON:0002371!8.38e-24!80;UBERON:0001474!1.47e-20!86;UBERON:0002405!7.61e-17!115;UBERON:0004765!6.22e-15!101;UBERON:0001434!6.22e-15!101;UBERON:0000178!1.06e-12!15;UBERON:0000179!1.06e-12!15;UBERON:0000463!1.06e-12!15;UBERON:0002384!9.62e-12!375;UBERON:0007023!1.69e-11!115;UBERON:0003081!1.84e-07!216 | |||
|ontology_enrichment_uberon_v019=UBERON:0000178;1.18e-16;15!UBERON:0000179;1.18e-16;15!UBERON:0000463;1.18e-16;15!UBERON:0002390;1.41e-12;32!UBERON:0002193;2.46e-07;42 | |||
|ontology_enrichment_uberon_v019_2=UBERON:0002390,2.52e-48,98;UBERON:0003061,2.52e-48,98;UBERON:0002193,1.76e-44,108;UBERON:0002405,1.06e-30,93;UBERON:0002371,2.04e-28,76;UBERON:0001474,4.66e-25,82;UBERON:0002384,6.72e-23,371;UBERON:0004765,2.61e-21,90;UBERON:0001434,1.59e-17,100;UBERON:0000178,1.88e-16,15;UBERON:0000179,1.88e-16,15;UBERON:0000463,1.88e-16,15;UBERON:0003081,5.39e-12,203;UBERON:0004177,3.48e-07,7;UBERON:0005057,3.48e-07,7 | |||
|phase1_expression=0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3.43860325865781,3.11982239909794,3.30585281517453,7.08055698328027,8.06041736004147,5.72819656269481,0,0,0,2.71135202031056,3.41206157969812,0.293600439334847,9.41792194504192,7.42014455639524,9.98250005292918,1.79132379391939,0.32389366601898,0.257575567634187,2.90796477559129,1.13362783106643,2.66842467306598,2.55671940596253,1.6446715520873,4.02618282163635,1.7261543539329,2.56160706529101,2.60130452877444,1.03423704220986,3.22742341791913,5.41705946377367,2.63539275359647,1.91034305040492,2.24723484445085,3.97909060082173,2.24650318953266,2.55734850319616,1.64925650093358,2.39356389145958,2.13112375266347,3.19230162491442,3.40431134814684,3.73693349397345,2.51248665256743,2.60741459210101,2.6062661364614,6.65939452896706,2.94622108790052,2.21523671208619,2.32380814943136,4.25208599930087,2.51590374610051,3.70684482783434,4.8056605709282,4.98249318760948,3.13514018115373,2.58591680358817,2.19196984517561,5.27988733383968,7.64594055766984,8.89509253863555,6.82768356106412,11.2110876370083,7.47178171940828,8.59358334620321,5.72432252721218,11.384259382189,5.87237189370939,11.4681968437569,1.32171328579026,5.04457706683382,0.263384084775077,5.90129310341499,7.46720449223413,6.37364646898479,2.67498392625085,2.60737813306872,2.36723902867367,5.84480185223734,2.45103005147382,2.94605907474837,3.54454231333794,4.06205795647523,5.25174410875268,3.12142434143708,2.46656856905514,3.31620021343018,2.60822777161547,2.52087157375503,4.54819407752512,4.18142095219907,3.17266159553185,3.83220493601921,5.15441168223945,3.54227568827304,3.82278497188916,4.55758417699493,4.75226022224187,6.32415500126646,6.2713439465665,2.49861453104692,6.86654030927649,2.46338399076314,5.44338206706778,9.62784704820626,7.38604459802275,0,0,0,0,0,0,0,0,0,0,0.087834785693126,0.196468613246569,0,0,1.29818957461873,2.08955684759121,1.99436940778298,2.38490624305342,1.14398982156026,1.85728750664782,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,32.9451043590158,34.9002237733493,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3.97316789473185,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.246217006087397,0.234004265139238,0,0,0,0,0,0,0,0.492663237895943,1.05658120815871,1.4512968087854,1.58531948758658,1.51490920111656,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,1.00451418286425,0,0,0,0,0,0,0,2.12961773587702,8.86638420908672,8.84073056924021,10.2674429023799,0,0,0,0,0,23.2192177423627,23.932916736322,11.603634376209,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,3.72182447021197,6.90285442619574,6.40365346820666,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.105551628892876,0,0,0,0,0,0,0,0,0,0.219259876645935,0.261435451024901,0,0,0,0.206082023295445,0,0,0,0,0,0,0,0,0,0,0,0.0852266274161009,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.30982349809975,0,0,0,0,0,0,0,0,0,0,0,0,0.188287601553558,0,0,0,0,8.11916174771471,10.7049208999933,13.1018853050057,7.38518503919146,6.9931586424653,7.78167973431261,8.64050299580984,8.72437693923697,0,0,0,1.11481905075431,0.577076851905779,1.20941133692304,0.478278818186467,0.997896857164083,2.68107518185313,4.86849240264931,1.62310970137278,4.7735520279288,6.61880569196257,1.41011906195721,45.1142058762121,0.50787533340481,1.1241165257259,1.61439765752838,2.98092366383228,2.74804275804612,0.614481528616916,0.894704431569664,1.16794399198336,0.976940477010201,0,1.23087398947712,0,1.6653598399891,2.81974010175699,0,0,0,2.45175445410452,0,0,0,0,0,0.422008249231538,0,0,0,0.796991953004279,6.90709788827869,0,0,3.32328974744888,0,0,0,3.5810065915881,0.0986434056369336,2.3948309234694,0,0,0.0927680981618513,0,0,0,0.724999575434793,0,0,0,0,0,0,0,0,0,0.110579259931225,0,0,0,0,0.307801034015188,0,0,0,0,0,0,0,3.06579894587209,0.31396051279005,3.65665700180344,0,0,0,0,0.476809736941136,0,0,0,0,0.995261931078505,0.353830258013357,0.611030144933625,1.18608451472249,2.22415090103705,2.19286093961456,0.202203398942031,0,0.702793337176017,1.45963831372533,0,0,0.394584402849391,1.20990716048664,0.30607276163049,0.505492637027904,0,0.103688191397247,0,0,0,0,0,0,0,0,0,0.52418000472609,0,0,0,0,0.193978032976839,0,0.90392296312213,0,0,0.0633107959558787,0,0,1.06726497369676,0,0,0,0,0,0,0,0,0,0,0,0,0.136905378891993,8.94226116468806,0,1.31443677139657,0.279282401272254,0.458320848023367,0,0.199679000498991,0,0.223171457441873,0.134366944973453,0,0,0,0,0,0,0.592713324460491,0,0.408610218334727,0,0,0,7.42413842119952,4.6428117273477,0.0607495566580247,0,0.236417121897595,0.0524545881349981,0,0,0,0.714695326373367,0,0,0,0,0,0,0,0,0,0,0,0.129282956361551,0.26446520348538,0,0,0.320362237703084,0,1.24271716604159,2.97699613087171,4.54506753365272,2.9230223611415,0,0,0,0,0,0,0,0,0,0,0.776503360757966,0.124192805882767,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0.276516872303462,1.1691618530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| |||
|short_description=p2@CCDC88B | |||
}} |
Revision as of 18:45, 10 September 2013
Short description: | p2@CCDC88B |
---|---|
Species: | Human (Homo sapiens) |
DPI dataset: | NA |
TSS-like-by-RIKEN-classifier(Yes/No): | NA |
DHS support(Yes/No): | NA |
Description: | CAGE_peak_2_at_CCDC88B_5end |
Coexpression cluster: | C57_Neutrophils_Eosinophils_Whole_CD4_CD8_CD19_Natural |
Association with transcript: | 10bp_to_ENST00000356786, ENST00000463837, uc001nzy.2, uc009ypo.1_5end |
EntrezGene: | CCDC88B |
HGNC: | 26757 |
UniProt: | A6NC98 |
Genome view: | ZENBU |
View on UCSC genome browser
CAGE Expression
- Click each plot point to find sample in table
Ontology-based sample term enrichment analysis<b>Summary:</b>This analysis has been performed by utilizing wilcoxon rank sum test.When the number of associated cells/tissues are > n , randomly sampled n cells/tissues are used for P value calculation with rank sum test. this process are repeated several times, and the P values are averaged on the log space <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source dataset<br>data
Ontology term | p-value | n |
---|---|---|
hematopoietic system | 2.52e-48 | 98 |
blood island | 2.52e-48 | 98 |
hemolymphoid system | 1.76e-44 | 108 |
immune system | 1.06e-30 | 93 |
bone marrow | 2.04e-28 | 76 |
bone element | 4.66e-25 | 82 |
connective tissue | 6.72e-23 | 371 |
skeletal element | 2.61e-21 | 90 |
skeletal system | 1.59e-17 | 100 |
blood | 1.88e-16 | 15 |
haemolymphatic fluid | 1.88e-16 | 15 |
organism substance | 1.88e-16 | 15 |
lateral plate mesoderm | 5.39e-12 | 203 |
hemopoietic organ | 3.48e-07 | 7 |
immune organ | 3.48e-07 | 7 |
Ontology term | p-value | n |
---|---|---|
hematologic cancer | 5.01e-11 | 51 |
immune system cancer | 5.01e-11 | 51 |
leukemia | 8.86e-08 | 39 |
Property "DHS support" (as page type) with input value "{{{DHSsupport}}}" contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.