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MCL coexpression mm9:2275: Difference between revisions

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{{MCL_coexpression_mm9
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|gostat_on_MCL_coexpression=GO:0004857;enzyme inhibitor activity;0.00253516577492826;18938,230157!GO:0004864;protein phosphatase inhibitor activity;0.0138721533729309;18938!GO:0019212;phosphatase inhibitor activity;0.0138721533729309;18938!GO:0019888;protein phosphatase regulator activity;0.0153256564215353;18938!GO:0019208;phosphatase regulator activity;0.0153256564215353;18938!GO:0004867;serine-type endopeptidase inhibitor activity;0.0367878587967453;230157!GO:0004866;endopeptidase inhibitor activity;0.039834565154955;230157!GO:0030414;protease inhibitor activity;0.039834565154955;230157!
}}

Latest revision as of 18:16, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr19:7049103..7049172,+p4@Ppp1r14b
Mm9::chr4:48598120..48598140,+p5@Tmeff1
Mm9::chr6:122436142..122436198,-p4@Rimklb
Mm9::chr6:122436270..122436322,-p5@Rimklb


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0004857enzyme inhibitor activity0.00253516577492826
GO:0004864protein phosphatase inhibitor activity0.0138721533729309
GO:0019212phosphatase inhibitor activity0.0138721533729309
GO:0019888protein phosphatase regulator activity0.0153256564215353
GO:0019208phosphatase regulator activity0.0153256564215353
GO:0004867serine-type endopeptidase inhibitor activity0.0367878587967453
GO:0004866endopeptidase inhibitor activity0.039834565154955
GO:0030414protease inhibitor activity0.039834565154955



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
neurectoderm6.34e-2364
neural plate6.34e-2364
presumptive neural plate6.34e-2364
central nervous system7.96e-2273
nervous system1.82e-2175
ectoderm-derived structure2.27e-2195
ectoderm2.27e-2195
presumptive ectoderm2.27e-2195
ecto-epithelium4.51e-2073
regional part of nervous system2.55e-1954
pre-chordal neural plate2.95e-1949
neural tube1.25e-1852
neural rod1.25e-1852
future spinal cord1.25e-1852
neural keel1.25e-1852
structure with developmental contribution from neural crest6.18e-1892
gray matter7.01e-1634
anterior neural tube3.12e-1540
regional part of brain6.06e-1546
brain6.34e-1547
future brain6.34e-1547
regional part of forebrain9.62e-1539
forebrain9.62e-1539
future forebrain9.62e-1539
brain grey matter1.25e-1229
regional part of telencephalon1.25e-1229
telencephalon1.25e-1229
cerebral cortex2.53e-0821
cerebral hemisphere2.53e-0821
pallium2.53e-0821


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.14.15047
MA0004.10.6888
MA0006.11.24418
MA0007.10.672186
MA0009.11.15569
MA0014.12.01483
MA0017.10.528196
MA0019.10.964875
MA0024.11.11019
MA0025.11.39562
MA0027.12.81824
MA0028.10.509589
MA0029.11.08753
MA0030.11.09438
MA0031.11.05719
MA0038.10.846479
MA0040.11.16866
MA0041.10.604221
MA0042.10.589368
MA0043.11.25564
MA0046.11.1929
MA0048.11.35097
MA0050.10.731539
MA0051.10.856094
MA0052.11.17701
MA0055.10.125758
MA0056.10
MA0057.11.29714
MA0058.10.581673
MA0059.10.59559
MA0060.10.403071
MA0061.10.438628
MA0063.10
MA0066.10.834648
MA0067.11.50873
MA0068.10.713436
MA0069.11.17737
MA0070.11.16732
MA0071.10.73062
MA0072.11.15853
MA0073.14.40992
MA0074.10.795862
MA0076.10.550092
MA0077.11.13603
MA0078.10.891476
MA0081.10.621611
MA0083.11.25482
MA0084.11.84013
MA0087.11.21037
MA0088.10.582815
MA0089.10
MA0090.10.650768
MA0091.10.703314
MA0092.10.651119
MA0093.11.29026
MA0095.10
MA0098.10
MA0100.10.783305
MA0101.10.605676
MA0103.10.540576
MA0105.10.313353
MA0106.10.899777
MA0107.10.533522
MA0108.20.989014
MA0109.10
MA0111.10.666525
MA0113.10.869608
MA0114.10.43587
MA0115.11.25852
MA0116.10.497293
MA0117.11.22527
MA0119.10.606338
MA0122.11.24573
MA0124.11.45461
MA0125.11.37907
MA0130.10
MA0131.10.960068
MA0132.10
MA0133.10
MA0135.11.29308
MA0136.10.817395
MA0139.10.365453
MA0140.10.78318
MA0141.10.563066
MA0142.11.04199
MA0143.10.887119
MA0144.10.439506
MA0145.10.21199
MA0146.11.07887
MA0147.12.0075
MA0148.10.706718
MA0149.10.611881
MA0062.20.856416
MA0035.20.788288
MA0039.21.47117
MA0138.20.951653
MA0002.20.368961
MA0137.20.559766
MA0104.21.77707
MA0047.20.845655
MA0112.20.608441
MA0065.21.14711
MA0150.10.67206
MA0151.10
MA0152.10.84577
MA0153.11.31015
MA0154.10.263609
MA0155.11.8891
MA0156.10.549102
MA0157.11.0083
MA0158.10
MA0159.10.465802
MA0160.10.71003
MA0161.10
MA0162.11.16288
MA0163.12.89766
MA0164.10.817786
MA0080.20.534538
MA0018.20.828253
MA0099.20.944966
MA0079.212.9386
MA0102.21.8929
MA0258.10.419871
MA0259.10.441366
MA0442.10
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