FF:11890-125D9: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00005183 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX007785;DRR008657;DRZ000082;DRZ001467;DRZ011432;DRZ012817 | ||
|ancestors_in_disease_facet=DOID: | |ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001737,UBERON:0000064,UBERON:0004119,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000072,UBERON:0010317,UBERON:0000065,UBERON:0001004,UBERON:0001557 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0000066,CL:0000255 | |||
|ancestors_in_disease_facet=DOID:4,DOID:162,DOID:14566,DOID:0050687,DOID:305 | |||
|ancestors_in_ff_facet=FF:0000102,FF:0000003,FF:0000210,FF:0000101,FF:0000001,FF:0000625,FF:0000350,FF:0000632,FF:0104978,FF:0000638,FF:0100297,FF:0101120,FF:0011133 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score=chr6:10415276..10415341,-!p2@TFAP2A!1.65!52.94!TFAP2A;;chr6:10415484..10415508,-!p3@TFAP2A!1.53!32.76!TFAP2A;;chr5:134369905..134369972,-!p1@PITX1!1.47!42.90!PITX1;;chr6:126240380..126240430,+!p2@NCOA7!1.45!69.60!NCOA7;;chr6:10412600..10412637,-!p1@TFAP2A!1.44!43.24!TFAP2A;;chr2:238592039..238592054,+!p4@LRRFIP1!1.44!26.25!LRRFIP1;;chr6:1312325..1312340,+!p1@FOXQ1!1.39!37.83!FOXQ1;;chr6:126240442..126240459,+!p4@NCOA7!1.39!30.22!NCOA7;;chr5:134369879..134369898,-!p2@PITX1!1.34!20.85!PITX1;;chr1:201979743..201979762,+!p1@ELF3!1.29!18.64!ELF3;;chr6:126240463..126240489,+!p6@NCOA7!1.24!18.20!NCOA7;;chr5:170736243..170736279,+!p1@TLX3!1.23!15.99!TLX3;;chr22:19748231..19748317,+!p1@TBX1!1.18!14.01!TBX1;;chr6:126240356..126240379,+!p7@NCOA7!1.16!16.54!NCOA7;;chr12:54380036..54380091,+!p4@HOXC10!1.16!13.57!HOXC10;;chr20:6748325..6748352,+!p1@BMP2!1.13!18.09!BMP2;;chr1:201979703..201979721,+!p2@ELF3!1.12!12.13!ELF3;;chr12:54378923..54378966,+!p1@HOXC10!1.12!12.13!HOXC10;;chr6:1389789..1389821,+!p1@FOXF2!1.11!16.43!FOXF2;;chr17:46682321..46682362,-!p1@HOXB6!1.11!12.02!HOXB6;;chr9:100615499..100615519,+!p1@FOXE1!1.11!11.91!FOXE1;;chr12:54380404..54380433,+!p3@HOXC10!1.09!11.36!HOXC10;;chr17:46687959..46688007,-!p2@HOXB7!1.08!15.44!HOXB7;;chr1:44513995..44514031,+!p1@KLF17!1.07!10.81!KLF17;;chr7:101917447..101917479,+!p4@CUX1!1.06!10.48!CUX1;;chrX:131624056..131624069,-!p2@MBNL3!1.04!13.57!MBNL3;;chr18:55102598..55102623,+!p1@ONECUT2!1.04!10.04!ONECUT2;;chr6:10412576..10412599,-!p5@TFAP2A!1.00!8.93!TFAP2A;;chr18:55102628..55102646,+!p2@ONECUT2!0.98!8.49!ONECUT2;;chr11:34663913..34663945,+!p6@EHF!0.97!8.27!EHF;;chr7:27224842..27224872,-!p1@HOXA11!0.97!8.27!HOXA11;;chr3:69915385..69915438,+!p3@MITF!0.96!8.05!MITF;;chr6:10412392..10412409,-!p4@TFAP2A!0.92!8.38!TFAP2A;;chr12:54332608..54332636,+!p1@HOXC13!0.92!7.39!HOXC13;;chr5:170736216..170736238,+!p2@TLX3!0.92!7.28!TLX3;;chr13:73633131..73633149,+!p1@KLF5!0.88!74.56!KLF5;;chr7:27239703..27239715,-!p1@HOXA13!0.86!6.29!HOXA13;;chr6:31126291..31126399,+!p1@TCF19!0.85!61.21!TCF19;;chr12:54379029..54379057,+!p2@HOXC10!0.85!6.07!HOXC10;;chr10:104155659..104155676,+!p4@NFKB2!0.84!7.61!NFKB2;;chr7:101917407..101917443,+!p3@CUX1!0.84!5.96!CUX1;;chr10:28034739..28034756,-!p1@MKX!0.84!5.85!MKX;;chrX:131623044..131623089,-!p1@MBNL3!0.82!24.60!MBNL3;;chr5:321810..321877,+!p1@AHRR!0.81!18.31!AHRR;;chr8:55370487..55370503,+!p1@SOX17!0.81!5.51!SOX17;;chr1:8934931..8934947,-!p4@ENO1!0.80!18.64!ENO1;;chr16:29818199..29818216,+!p11@MAZ!0.80!9.04!MAZ;;chr17:17726907..17726958,-!p2@SREBF1!0.79!34.85!SREBF1;;chr21:38071430..38071456,+!p1@SIM2!0.79!5.18!SIM2;;chr11:34664014..34664045,+!p4@EHF!0.78!5.07!EHF;;chr12:3068544..3068597,+!p1@TEAD4!0.77!31.99!TEAD4;;chr12:80084737..80084763,-!p3@PAWR!0.77!19.96!PAWR;;chr1:45805872..45805900,+!p2@TOE1!0.77!12.68!TOE1;;chr1:151804244..151804310,-!p1@RORC!0.77!4.85!RORC;;chr15:96875657..96875760,+!p14@NR2F2!0.76!8.16!NR2F2;;chr15:67418119..67418162,+!p5@SMAD3!0.76!5.40!SMAD3;;chr7:27224795..27224840,-!p2@HOXA11!0.75!4.63!HOXA11;;chr8:128748308..128748324,+!p2@MYC!0.74!138.64!MYC;;chr10:51572408..51572454,+!p3@NCOA4!0.74!29.12!NCOA4;;chr12:54332652..54332671,+!p2@HOXC13!0.74!4.52!HOXC13;;chr2:178129853..178129860,-!p14@NFE2L2!0.74!4.52!NFE2L2;;chr1:8938709..8938720,-!p3@ENO1!0.73!235.70!ENO1;;chr3:138665937..138665968,-!p1@FOXL2!0.73!4.41!FOXL2;;chr20:42295745..42295765,+!p1@MYBL2!0.72!77.76!MYBL2;;chr2:46524897..46524911,+!p2@EPAS1!0.72!12.90!EPAS1;;chr2:172967621..172967637,-!p1@DLX2!0.72!12.57!DLX2;;chr17:46688334..46688385,-!p1@HOXB7!0.72!6.51!HOXB7;;chr7:101917482..101917507,+!p6@CUX1!0.72!4.30!CUX1;;chr14:37131058..37131139,+!p1@PAX9!0.72!4.30!PAX9;;chr2:45236540..45236577,-!p1@SIX2!0.71!4.08!SIX2;;chr12:2986275..2986363,-!p1@FOXM1!0.70!45.22!FOXM1;;chr20:42295713..42295738,+!p2@MYBL2!0.70!26.91!MYBL2;;chr12:72056800..72056834,+!p1@THAP2!0.70!5.62!THAP2;;chr6:10415263..10415274,-!p8@TFAP2A!0.70!3.97!TFAP2A;;chrX:131623026..131623039,-!p5@MBNL3!0.70!3.97!MBNL3;;chr17:26697276..26697303,-!p2@SEBOX,p2@VTN!0.69!3.86!SEBOX;;chr6:126240490..126240501,+!p11@NCOA7!0.69!3.86!NCOA7;;chr20:30193083..30193098,+!p1@ID1!0.68!354.71!ID1;;chr6:1389989..1390019,+!p2@FOXF2!0.68!3.75!FOXF2;;chr12:54379136..54379150,+!p4@HOXC5!0.68!3.75!HOXC5;;chr22:19746969..19746987,+!p2@TBX1!0.68!3.75!TBX1;;chr1:23885981..23886002,-!p1@ID3!0.67!753.31!ID3;;chr17:7492684..7492778,-!p2@SOX15!0.67!8.60!SOX15;;chr20:62680984..62680999,-!p1@SOX18!0.67!5.07!SOX18;;chr3:69915369..69915381,+!p4@MITF!0.67!3.64!MITF;;chr17:48072574..48072597,-!p1@DLX3!0.67!3.64!DLX3;;chr12:52445218..52445237,+!p1@NR4A1!0.66!51.95!NR4A1;;chr16:29818160..29818188,+!p6@MAZ!0.66!18.97!MAZ;;chr6:10419824..10419840,-!p9@TFAP2A!0.66!3.53!TFAP2A;;chr13:100623375..100623425,-!p1@ZIC5!0.66!3.53!ZIC5;;chr2:178128149..178128198,-!p2@NFE2L2!0.65!21.29!NFE2L2;;chr17:41277372..41277418,-!p1@BRCA1!0.65!14.34!BRCA1;;chr17:26697304..26697335,-!p1@SEBOX,p1@VTN!0.65!3.42!SEBOX;;chr12:54379477..5437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| |||
|ffid_belonging_in_development=UBERON:0008947,UBERON:0002532,UBERON:0006595,UBERON:0010316 | |||
|fonse_cell_line=FF:0101120 | |fonse_cell_line=FF:0101120 | ||
|fonse_cell_line_closure=FF:0101120 | |fonse_cell_line_closure=FF:0101120 | ||
Line 34: | Line 41: | ||
|fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000638,FF:0011133,FF:11890-125D9 | |fonse_treatment_closure=FF:0000625,FF:0000632,FF:0000638,FF:0011133,FF:11890-125D9 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep1.CNhs13477.11890-125D9.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep1.CNhs13477.11890-125D9.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep1.CNhs13477.11890-125D9.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep1.CNhs13477.11890-125D9.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.cell_line.hCAGE/Hep-2%2520cells%2520treated%2520with%2520Streptococci%2520strain%25205448%252c%2520biol_rep1.CNhs13477.11890-125D9.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:11890-125D9 | |id=FF:11890-125D9 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0011133 | ||
|is_obsolete= | |||
|library_id=CNhs13477 | |||
|library_id_phase_based=2:CNhs13477 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;11890 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;11890 | |||
|name=Hep-2 cells treated with Streptococci strain 5448, biol_rep1 | |name=Hep-2 cells treated with Streptococci strain 5448, biol_rep1 | ||
|namespace= | |namespace= | ||
Line 41: | Line 60: | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13477,LSID1024,release012,COMPLETED | |profile_hcage=CNhs13477,LSID1024,release012,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=125 | |rna_box=125 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 56: | Line 78: | ||
|rna_weight_ug=10 | |rna_weight_ug=10 | ||
|sample_age=56 | |sample_age=56 | ||
|sample_category=cell lines | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line=Hep-2 | |sample_cell_line=Hep-2 | ||
Line 68: | Line 91: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.22116359874866e-260!GO:0043226;organelle;2.50955799347903e-212!GO:0043229;intracellular organelle;1.15548262156147e-211!GO:0043227;membrane-bound organelle;1.19905957544149e-211!GO:0043231;intracellular membrane-bound organelle;1.46764581439651e-211!GO:0005737;cytoplasm;1.10241730190757e-202!GO:0044422;organelle part;1.18889880347502e-175!GO:0044446;intracellular organelle part;1.55808517390615e-173!GO:0044444;cytoplasmic part;1.63298625553375e-148!GO:0032991;macromolecular complex;3.72242392435562e-122!GO:0030529;ribonucleoprotein complex;5.25208308250202e-103!GO:0005739;mitochondrion;3.87818464152468e-97!GO:0044237;cellular metabolic process;1.12207313390284e-93!GO:0044238;primary metabolic process;3.40849573837646e-90!GO:0043233;organelle lumen;1.97579287193881e-89!GO:0031974;membrane-enclosed lumen;1.97579287193881e-89!GO:0044428;nuclear part;2.56793411231312e-89!GO:0003723;RNA binding;3.40255385057965e-85!GO:0005634;nucleus;6.35098198893564e-84!GO:0043170;macromolecule metabolic process;2.74450575889982e-77!GO:0005515;protein binding;2.08115456566916e-68!GO:0006396;RNA processing;2.95029252456706e-63!GO:0044429;mitochondrial part;2.17993918472199e-62!GO:0005840;ribosome;4.89597306210179e-62!GO:0043234;protein complex;1.03568636408438e-61!GO:0006412;translation;2.06688847639039e-59!GO:0031090;organelle membrane;1.23706292402875e-56!GO:0031967;organelle envelope;4.39101599148214e-54!GO:0031975;envelope;6.86566668994866e-54!GO:0003735;structural constituent of ribosome;1.3488923731459e-53!GO:0031981;nuclear lumen;2.73424804321612e-52!GO:0044249;cellular biosynthetic process;5.38684726600529e-52!GO:0009058;biosynthetic process;2.22207201970602e-51!GO:0016043;cellular component organization and biogenesis;6.64068548957492e-49!GO:0033279;ribosomal subunit;6.72206713915365e-47!GO:0043228;non-membrane-bound organelle;9.21165321816773e-45!GO:0043232;intracellular non-membrane-bound organelle;9.21165321816773e-45!GO:0006259;DNA metabolic process;7.72992846677365e-44!GO:0019538;protein metabolic process;2.07661295875363e-43!GO:0009059;macromolecule biosynthetic process;3.35411652383969e-43!GO:0005829;cytosol;3.98206328838694e-43!GO:0016071;mRNA metabolic process;3.28605643087797e-42!GO:0015031;protein transport;6.70447310186871e-42!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;7.78720087219708e-42!GO:0033036;macromolecule localization;8.85441949717259e-42!GO:0008380;RNA splicing;6.54079131537757e-41!GO:0005740;mitochondrial envelope;1.18997774432682e-39!GO:0043283;biopolymer metabolic process;1.41984051838343e-39!GO:0022613;ribonucleoprotein complex biogenesis and assembly;2.18442817771171e-38!GO:0045184;establishment of protein localization;2.34675393381461e-38!GO:0006397;mRNA processing;3.52548514268341e-38!GO:0019866;organelle inner membrane;4.37659877590491e-38!GO:0044260;cellular macromolecule metabolic process;5.18022173755913e-38!GO:0008104;protein localization;6.6566095071048e-38!GO:0044267;cellular protein metabolic process;8.04730435967154e-38!GO:0031966;mitochondrial membrane;2.74676129781864e-37!GO:0010467;gene expression;5.62268392576404e-37!GO:0006996;organelle organization and biogenesis;5.67512453322274e-37!GO:0065003;macromolecular complex assembly;1.01452029468167e-36!GO:0005743;mitochondrial inner membrane;6.0599792597876e-36!GO:0046907;intracellular transport;4.74811017545651e-33!GO:0007049;cell cycle;8.06393631375136e-33!GO:0022607;cellular component assembly;5.39371265983049e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.25720134215257e-31!GO:0005681;spliceosome;6.10943656731347e-30!GO:0005654;nucleoplasm;6.62287733459547e-30!GO:0031980;mitochondrial lumen;6.06668393635987e-28!GO:0005759;mitochondrial matrix;6.06668393635987e-28!GO:0006886;intracellular protein transport;6.29752794598085e-28!GO:0000166;nucleotide binding;7.48393389293187e-27!GO:0005730;nucleolus;5.07604121775514e-26!GO:0006119;oxidative phosphorylation;5.41693128980368e-26!GO:0044445;cytosolic part;5.86158910853649e-26!GO:0044455;mitochondrial membrane part;7.73485569955685e-26!GO:0006974;response to DNA damage stimulus;1.10632861084651e-25!GO:0015934;large ribosomal subunit;3.38219095151268e-25!GO:0000278;mitotic cell cycle;4.82169165637492e-25!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;7.08567738614371e-25!GO:0016462;pyrophosphatase activity;7.19489843911381e-25!GO:0016817;hydrolase activity, acting on acid anhydrides;1.09979103186205e-24!GO:0022402;cell cycle process;1.53202953202504e-24!GO:0005694;chromosome;1.93849530570946e-24!GO:0017111;nucleoside-triphosphatase activity;6.74745943554103e-24!GO:0044451;nucleoplasm part;1.39178105671179e-23!GO:0015935;small ribosomal subunit;6.69495716655842e-23!GO:0003676;nucleic acid binding;1.19832077311834e-22!GO:0044427;chromosomal part;1.30058789974424e-22!GO:0051186;cofactor metabolic process;7.87070321470824e-22!GO:0006281;DNA repair;1.09828745293191e-21!GO:0051649;establishment of cellular localization;1.48768297272336e-21!GO:0006457;protein folding;1.71646981001205e-21!GO:0051641;cellular localization;1.89923416526972e-21!GO:0016874;ligase activity;4.70620003360322e-21!GO:0012505;endomembrane system;5.79147883569397e-21!GO:0005783;endoplasmic reticulum;1.17974437162536e-20!GO:0022403;cell cycle phase;8.01003734252064e-20!GO:0006260;DNA replication;9.28028644083845e-20!GO:0005746;mitochondrial respiratory chain;1.00395514846376e-19!GO:0042254;ribosome biogenesis and assembly;1.21723190703194e-19!GO:0022618;protein-RNA complex assembly;1.78821673157326e-19!GO:0005761;mitochondrial ribosome;2.847189880023e-19!GO:0000313;organellar ribosome;2.847189880023e-19!GO:0009719;response to endogenous stimulus;4.90359690534256e-19!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.53895980648548e-18!GO:0000087;M phase of mitotic cell cycle;1.94658910312501e-18!GO:0032553;ribonucleotide binding;2.3080366895591e-18!GO:0032555;purine ribonucleotide binding;2.3080366895591e-18!GO:0007067;mitosis;3.56003302621295e-18!GO:0017076;purine nucleotide binding;4.38696086255364e-18!GO:0044432;endoplasmic reticulum part;7.24888897528547e-18!GO:0006732;coenzyme metabolic process;8.68006579270274e-18!GO:0050136;NADH dehydrogenase (quinone) activity;1.264193601764e-17!GO:0003954;NADH dehydrogenase activity;1.264193601764e-17!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.264193601764e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.882183063579e-17!GO:0044265;cellular macromolecule catabolic process;4.92721165196568e-17!GO:0005524;ATP binding;6.82083585196107e-17!GO:0051276;chromosome organization and biogenesis;7.61170065370318e-17!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);7.9658765679966e-17!GO:0044248;cellular catabolic process;8.95631480320879e-17!GO:0008135;translation factor activity, nucleic acid binding;1.07866718090965e-16!GO:0032559;adenyl ribonucleotide binding;1.27492326344318e-16!GO:0016887;ATPase activity;3.25279712823977e-16!GO:0030554;adenyl nucleotide binding;4.09868586185726e-16!GO:0006399;tRNA metabolic process;4.18690802381779e-16!GO:0042623;ATPase activity, coupled;5.54448324964818e-16!GO:0042775;organelle ATP synthesis coupled electron transport;6.61552795597572e-16!GO:0042773;ATP synthesis coupled electron transport;6.61552795597572e-16!GO:0006512;ubiquitin cycle;7.00213669296388e-16!GO:0006605;protein targeting;1.02674593395072e-15!GO:0030964;NADH dehydrogenase complex (quinone);1.40304509731245e-15!GO:0045271;respiratory chain complex I;1.40304509731245e-15!GO:0005747;mitochondrial respiratory chain complex I;1.40304509731245e-15!GO:0000279;M phase;1.52712307370216e-15!GO:0044453;nuclear membrane part;2.0344710884915e-15!GO:0051301;cell division;2.23749614010067e-15!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);2.43603435704896e-15!GO:0051603;proteolysis involved in cellular protein catabolic process;3.27312701407305e-15!GO:0005635;nuclear envelope;3.72549459758119e-15!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;4.32521502445337e-15!GO:0019941;modification-dependent protein catabolic process;5.72304198175959e-15!GO:0043632;modification-dependent macromolecule catabolic process;5.72304198175959e-15!GO:0000398;nuclear mRNA splicing, via spliceosome;5.81125483759138e-15!GO:0000375;RNA splicing, via transesterification reactions;5.81125483759138e-15!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;5.81125483759138e-15!GO:0044257;cellular protein catabolic process;1.00939708126307e-14!GO:0051082;unfolded protein binding;1.35368750001618e-14!GO:0006511;ubiquitin-dependent protein catabolic process;1.37899284914409e-14!GO:0031965;nuclear membrane;1.45447948953588e-14!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;2.49586998256195e-14!GO:0042175;nuclear envelope-endoplasmic reticulum network;3.60969550530519e-14!GO:0048770;pigment granule;6.06178757512971e-14!GO:0042470;melanosome;6.06178757512971e-14!GO:0009055;electron carrier activity;7.62463548941319e-14!GO:0005789;endoplasmic reticulum membrane;8.64097753042264e-14!GO:0008134;transcription factor binding;9.52530589294742e-14!GO:0006325;establishment and/or maintenance of chromatin architecture;1.19859300466375e-13!GO:0006364;rRNA processing;1.21292106340553e-13!GO:0009057;macromolecule catabolic process;1.24308968957119e-13!GO:0000785;chromatin;1.40821537280524e-13!GO:0043285;biopolymer catabolic process;1.64320212383076e-13!GO:0005643;nuclear pore;2.62870190958873e-13!GO:0016070;RNA metabolic process;2.72931392993996e-13!GO:0016072;rRNA metabolic process;3.14915073596598e-13!GO:0003743;translation initiation factor activity;3.47288837822471e-13!GO:0000074;regulation of progression through cell cycle;3.5199644385294e-13!GO:0051726;regulation of cell cycle;3.58978654812915e-13!GO:0006323;DNA packaging;3.98489095911904e-13!GO:0065002;intracellular protein transport across a membrane;7.80642041456567e-13!GO:0006413;translational initiation;1.42636288936696e-12!GO:0009259;ribonucleotide metabolic process;1.57733836610254e-12!GO:0012501;programmed cell death;1.95194583508147e-12!GO:0048193;Golgi vesicle transport;2.37649774443434e-12!GO:0006915;apoptosis;3.64089772173726e-12!GO:0051188;cofactor biosynthetic process;4.28602247932311e-12!GO:0006163;purine nucleotide metabolic process;4.7186974007705e-12!GO:0006913;nucleocytoplasmic transport;5.42557821968046e-12!GO:0006333;chromatin assembly or disassembly;9.15376021192726e-12!GO:0004386;helicase activity;1.23320185383451e-11!GO:0050657;nucleic acid transport;1.38619415907896e-11!GO:0051236;establishment of RNA localization;1.38619415907896e-11!GO:0050658;RNA transport;1.38619415907896e-11!GO:0006403;RNA localization;1.490173133091e-11!GO:0051169;nuclear transport;1.69238439570849e-11!GO:0065004;protein-DNA complex assembly;2.24424298850089e-11!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.3056805207857e-11!GO:0046930;pore complex;2.47151509311185e-11!GO:0016604;nuclear body;2.90661427192695e-11!GO:0008026;ATP-dependent helicase activity;3.88933018606209e-11!GO:0030163;protein catabolic process;4.79788164395537e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;5.21776680183744e-11!GO:0008219;cell death;5.27787812831398e-11!GO:0016265;death;5.27787812831398e-11!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.42693390159493e-11!GO:0009150;purine ribonucleotide metabolic process;5.47423482014893e-11!GO:0009260;ribonucleotide biosynthetic process;6.83016229944386e-11!GO:0006164;purine nucleotide biosynthetic process;8.6623803852097e-11!GO:0006461;protein complex assembly;2.06407463839562e-10!GO:0006446;regulation of translational initiation;2.43188926614528e-10!GO:0007005;mitochondrion organization and biogenesis;2.47067461003481e-10!GO:0009108;coenzyme biosynthetic process;3.09672978307121e-10!GO:0008565;protein transporter activity;4.0872042568799e-10!GO:0009060;aerobic respiration;4.0872042568799e-10!GO:0009117;nucleotide metabolic process;4.58350428872434e-10!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;4.64684364495202e-10!GO:0005794;Golgi apparatus;5.44525805831463e-10!GO:0009199;ribonucleoside triphosphate metabolic process;6.11864272367545e-10!GO:0016779;nucleotidyltransferase activity;6.18908910806208e-10!GO:0009141;nucleoside triphosphate metabolic process;7.69616547154872e-10!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;7.69616547154872e-10!GO:0004812;aminoacyl-tRNA ligase activity;7.69616547154872e-10!GO:0016875;ligase activity, forming carbon-oxygen bonds;7.69616547154872e-10!GO:0006366;transcription from RNA polymerase II promoter;7.88767097000899e-10!GO:0016192;vesicle-mediated transport;7.9374546169933e-10!GO:0051028;mRNA transport;9.40916674256632e-10!GO:0016491;oxidoreductase activity;9.50618969148254e-10!GO:0009152;purine ribonucleotide biosynthetic process;1.01048820941372e-09!GO:0030532;small nuclear ribonucleoprotein complex;1.05687513016325e-09!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;1.27237110876219e-09!GO:0008639;small protein conjugating enzyme activity;1.40982067894958e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;1.52888499658918e-09!GO:0009144;purine nucleoside triphosphate metabolic process;1.52888499658918e-09!GO:0043038;amino acid activation;1.61875143913512e-09!GO:0006418;tRNA aminoacylation for protein translation;1.61875143913512e-09!GO:0043039;tRNA aminoacylation;1.61875143913512e-09!GO:0045333;cellular respiration;1.69662900917646e-09!GO:0006261;DNA-dependent DNA replication;1.74864417248063e-09!GO:0006334;nucleosome assembly;1.83686598035859e-09!GO:0043412;biopolymer modification;1.84470714779547e-09!GO:0015986;ATP synthesis coupled proton transport;1.94209673272343e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.94209673272343e-09!GO:0043566;structure-specific DNA binding;3.01457220620024e-09!GO:0009056;catabolic process;3.02183145871583e-09!GO:0003697;single-stranded DNA binding;3.32558476757996e-09!GO:0004842;ubiquitin-protein ligase activity;4.2222864678764e-09!GO:0009142;nucleoside triphosphate biosynthetic process;4.2222864678764e-09!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.2222864678764e-09!GO:0019787;small conjugating protein ligase activity;4.72256692566366e-09!GO:0046034;ATP metabolic process;4.95808318512063e-09!GO:0031497;chromatin assembly;5.22094247829974e-09!GO:0017038;protein import;6.06784211135898e-09!GO:0016607;nuclear speck;7.0783165437618e-09!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;1.11650135228825e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;1.11650135228825e-08!GO:0015078;hydrogen ion transmembrane transporter activity;1.63647536963552e-08!GO:0016881;acid-amino acid ligase activity;2.30637530755928e-08!GO:0006099;tricarboxylic acid cycle;2.30637530755928e-08!GO:0046356;acetyl-CoA catabolic process;2.30637530755928e-08!GO:0019829;cation-transporting ATPase activity;2.51258249299499e-08!GO:0005819;spindle;2.60214695015662e-08!GO:0051329;interphase of mitotic cell cycle;2.65263429755538e-08!GO:0016469;proton-transporting two-sector ATPase complex;2.82443837102142e-08!GO:0051325;interphase;2.87144812800729e-08!GO:0006754;ATP biosynthetic process;2.9414924355895e-08!GO:0006753;nucleoside phosphate metabolic process;2.9414924355895e-08!GO:0000775;chromosome, pericentric region;3.23089538290641e-08!GO:0006084;acetyl-CoA metabolic process;3.34628770674088e-08!GO:0042981;regulation of apoptosis;3.53911671698629e-08!GO:0043067;regulation of programmed cell death;3.58439925270797e-08!GO:0006752;group transfer coenzyme metabolic process;3.95324114402308e-08!GO:0016787;hydrolase activity;4.15530660780034e-08!GO:0003712;transcription cofactor activity;4.74069552826747e-08!GO:0016740;transferase activity;5.99642015197298e-08!GO:0005793;ER-Golgi intermediate compartment;8.56835224830839e-08!GO:0008033;tRNA processing;9.26601536437209e-08!GO:0006464;protein modification process;1.75174482949998e-07!GO:0005657;replication fork;2.07008647046904e-07!GO:0045259;proton-transporting ATP synthase complex;2.38810046171094e-07!GO:0003899;DNA-directed RNA polymerase activity;2.76854933421125e-07!GO:0043623;cellular protein complex assembly;3.12847537401642e-07!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;3.18524473521687e-07!GO:0051187;cofactor catabolic process;3.314065694965e-07!GO:0005762;mitochondrial large ribosomal subunit;3.35418205724183e-07!GO:0000315;organellar large ribosomal subunit;3.35418205724183e-07!GO:0016568;chromatin modification;4.00023829560017e-07!GO:0006916;anti-apoptosis;4.68437730010083e-07!GO:0006888;ER to Golgi vesicle-mediated transport;4.76933053435294e-07!GO:0005839;proteasome core complex (sensu Eukaryota);4.77772746359817e-07!GO:0009109;coenzyme catabolic process;4.78131454537571e-07!GO:0008094;DNA-dependent ATPase activity;5.66814616414334e-07!GO:0006091;generation of precursor metabolites and energy;5.78613680856827e-07!GO:0043069;negative regulation of programmed cell death;6.06958878626938e-07!GO:0005667;transcription factor complex;7.15392230410725e-07!GO:0000245;spliceosome assembly;7.72304927697679e-07!GO:0030120;vesicle coat;7.96527763905649e-07!GO:0030662;coated vesicle membrane;7.96527763905649e-07!GO:0015630;microtubule cytoskeleton;8.6446811139809e-07!GO:0043066;negative regulation of apoptosis;9.80024857391991e-07!GO:0008654;phospholipid biosynthetic process;1.07029103778354e-06!GO:0031202;RNA splicing factor activity, transesterification mechanism;1.25808269770121e-06!GO:0007051;spindle organization and biogenesis;1.36299133237986e-06!GO:0000075;cell cycle checkpoint;1.48406385851872e-06!GO:0032446;protein modification by small protein conjugation;1.64176492675254e-06!GO:0003724;RNA helicase activity;1.73054966591513e-06!GO:0043687;post-translational protein modification;2.14343700694087e-06!GO:0051427;hormone receptor binding;2.17848631722683e-06!GO:0044452;nucleolar part;2.34385435521965e-06!GO:0000079;regulation of cyclin-dependent protein kinase activity;2.4528641850306e-06!GO:0016567;protein ubiquitination;2.59032916951705e-06!GO:0004298;threonine endopeptidase activity;2.65226955058354e-06!GO:0009165;nucleotide biosynthetic process;2.85525547162932e-06!GO:0048523;negative regulation of cellular process;2.97857501028319e-06!GO:0000314;organellar small ribosomal subunit;2.98159414010031e-06!GO:0005763;mitochondrial small ribosomal subunit;2.98159414010031e-06!GO:0016853;isomerase activity;3.05549834921786e-06!GO:0005768;endosome;3.08084260822525e-06!GO:0051246;regulation of protein metabolic process;3.42733274873624e-06!GO:0000786;nucleosome;3.7968480795455e-06!GO:0048475;coated membrane;3.8926707502291e-06!GO:0030117;membrane coat;3.8926707502291e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;4.48087384437301e-06!GO:0051170;nuclear import;5.10628473598441e-06!GO:0035257;nuclear hormone receptor binding;5.18265410057114e-06!GO:0051168;nuclear export;5.82550197773338e-06!GO:0000151;ubiquitin ligase complex;6.66995372205471e-06!GO:0006613;cotranslational protein targeting to membrane;6.95249860474382e-06!GO:0006082;organic acid metabolic process;7.91142980865038e-06!GO:0019752;carboxylic acid metabolic process;7.95088553873229e-06!GO:0006626;protein targeting to mitochondrion;9.35473188351678e-06!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.01185045918064e-05!GO:0006302;double-strand break repair;1.28839861947546e-05!GO:0005788;endoplasmic reticulum lumen;1.54738564497807e-05!GO:0008168;methyltransferase activity;1.66600755777024e-05!GO:0016741;transferase activity, transferring one-carbon groups;1.76834150543345e-05!GO:0007249;I-kappaB kinase/NF-kappaB cascade;1.82086463602065e-05!GO:0003682;chromatin binding;1.89524783974888e-05!GO:0005813;centrosome;1.89524783974888e-05!GO:0006606;protein import into nucleus;1.93175331892139e-05!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;2.09365696291818e-05!GO:0046483;heterocycle metabolic process;2.12838819145154e-05!GO:0045454;cell redox homeostasis;2.22458522910435e-05!GO:0031324;negative regulation of cellular metabolic process;2.26019934960195e-05!GO:0006414;translational elongation;2.40865653285196e-05!GO:0006839;mitochondrial transport;2.9118595824189e-05!GO:0046474;glycerophospholipid biosynthetic process;3.1285496105657e-05!GO:0003924;GTPase activity;3.20115529794628e-05!GO:0007088;regulation of mitosis;3.25191314322535e-05!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;3.32191914464374e-05!GO:0015399;primary active transmembrane transporter activity;3.32191914464374e-05!GO:0005815;microtubule organizing center;3.73334545394377e-05!GO:0043681;protein import into mitochondrion;4.1883370067194e-05!GO:0015980;energy derivation by oxidation of organic compounds;4.39303322703402e-05!GO:0003690;double-stranded DNA binding;5.07059874207721e-05!GO:0008186;RNA-dependent ATPase activity;5.1580853139484e-05!GO:0043021;ribonucleoprotein binding;6.15643730154326e-05!GO:0003713;transcription coactivator activity;6.22948430916112e-05!GO:0030867;rough endoplasmic reticulum membrane;6.59863714648835e-05!GO:0048519;negative regulation of biological process;7.23772858341136e-05!GO:0016772;transferase activity, transferring phosphorus-containing groups;7.3714294588991e-05!GO:0005753;mitochondrial proton-transporting ATP synthase complex;7.66993731859657e-05!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;7.71472329625394e-05!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;7.95075140640474e-05!GO:0019867;outer membrane;8.4985207334448e-05!GO:0051052;regulation of DNA metabolic process;8.57168557955618e-05!GO:0009892;negative regulation of metabolic process;8.98422281154891e-05!GO:0005770;late endosome;9.10771159209182e-05!GO:0016126;sterol biosynthetic process;9.20549137068814e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;9.43555586647451e-05!GO:0006357;regulation of transcription from RNA polymerase II promoter;9.58971665282684e-05!GO:0016859;cis-trans isomerase activity;0.000105550257632359!GO:0045786;negative regulation of progression through cell cycle;0.000106866911056701!GO:0044440;endosomal part;0.000107101293458603!GO:0010008;endosome membrane;0.000107101293458603!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000108296149499237!GO:0006383;transcription from RNA polymerase III promoter;0.000109444862445183!GO:0046489;phosphoinositide biosynthetic process;0.000109444862445183!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.000109703896134601!GO:0000776;kinetochore;0.000110098143848651!GO:0003684;damaged DNA binding;0.000112891214632479!GO:0031968;organelle outer membrane;0.000114930635979452!GO:0006612;protein targeting to membrane;0.000128939614739836!GO:0051789;response to protein stimulus;0.000142395929524088!GO:0006986;response to unfolded protein;0.000142395929524088!GO:0004004;ATP-dependent RNA helicase activity;0.000145512550409481!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.000146477449961743!GO:0006793;phosphorus metabolic process;0.000158095732286387!GO:0006796;phosphate metabolic process;0.000158095732286387!GO:0048471;perinuclear region of cytoplasm;0.000169873376337626!GO:0008610;lipid biosynthetic process;0.000178128717589324!GO:0000059;protein import into nucleus, docking;0.000189985602567491!GO:0005773;vacuole;0.000195508975368606!GO:0016564;transcription repressor activity;0.000207035093956843!GO:0050662;coenzyme binding;0.000209690673058665!GO:0007059;chromosome segregation;0.000232421884225914!GO:0030880;RNA polymerase complex;0.000260089825031104!GO:0004527;exonuclease activity;0.000275878055691086!GO:0042802;identical protein binding;0.000280189784062966!GO:0006310;DNA recombination;0.000288409905115981!GO:0003678;DNA helicase activity;0.000326265443223489!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000333182033182221!GO:0005525;GTP binding;0.000336441667112777!GO:0006695;cholesterol biosynthetic process;0.000338144665660611!GO:0005741;mitochondrial outer membrane;0.000367960831947312!GO:0051087;chaperone binding;0.000379666984701864!GO:0019843;rRNA binding;0.000391657638264234!GO:0000226;microtubule cytoskeleton organization and biogenesis;0.00041641036714455!GO:0004518;nuclease activity;0.000423167068945493!GO:0030176;integral to endoplasmic reticulum membrane;0.000437388911309967!GO:0009112;nucleobase metabolic process;0.000442858113330891!GO:0016310;phosphorylation;0.000444629736198997!GO:0043596;nuclear replication fork;0.000457800272892299!GO:0043284;biopolymer biosynthetic process;0.000471327923779614!GO:0008361;regulation of cell size;0.000474239812525069!GO:0033116;ER-Golgi intermediate compartment membrane;0.000474239812525069!GO:0006520;amino acid metabolic process;0.000490722270175293!GO:0006650;glycerophospholipid metabolic process;0.000492047955845025!GO:0005791;rough endoplasmic reticulum;0.000498539290171144!GO:0051920;peroxiredoxin activity;0.000507500032053182!GO:0003729;mRNA binding;0.000515155125214339!GO:0016049;cell growth;0.00053343639503096!GO:0007006;mitochondrial membrane organization and biogenesis;0.00053343639503096!GO:0001558;regulation of cell growth;0.00053343639503096!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000547493401348239!GO:0005684;U2-dependent spliceosome;0.00056736138509896!GO:0000323;lytic vacuole;0.00056736138509896!GO:0005764;lysosome;0.00056736138509896!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000580443763585863!GO:0031072;heat shock protein binding;0.00058112776556538!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00062987471931579!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.000639213536905892!GO:0000428;DNA-directed RNA polymerase complex;0.000639213536905892!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.000656047689665528!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.000656047689665528!GO:0016563;transcription activator activity;0.000671113920581006!GO:0016363;nuclear matrix;0.000683318962635349!GO:0031252;leading edge;0.000721130424110089!GO:0048037;cofactor binding;0.000725829801535306!GO:0046467;membrane lipid biosynthetic process;0.000733051763619904!GO:0065009;regulation of a molecular function;0.000766023410139312!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.000767593686848379!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.000767593686848379!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.000767593686848379!GO:0044431;Golgi apparatus part;0.000786991662312246!GO:0005885;Arp2/3 protein complex;0.000820272772303062!GO:0006950;response to stress;0.000827654994463219!GO:0006275;regulation of DNA replication;0.000833710147858192!GO:0005798;Golgi-associated vesicle;0.000928583184530913!GO:0016891;endoribonuclease activity, producing 5'-phosphomonoesters;0.000944597153526566!GO:0006284;base-excision repair;0.00098344007706471!GO:0006506;GPI anchor biosynthetic process;0.00098344007706471!GO:0051287;NAD binding;0.00098344007706471!GO:0005048;signal sequence binding;0.00100233025532059!GO:0030132;clathrin coat of coated pit;0.00103209098161889!GO:0000082;G1/S transition of mitotic cell cycle;0.00118032275796231!GO:0003711;transcription elongation regulator activity;0.00121849454516931!GO:0032508;DNA duplex unwinding;0.00121908714242066!GO:0032392;DNA geometric change;0.00121908714242066!GO:0051540;metal cluster binding;0.00127338451304409!GO:0051536;iron-sulfur cluster binding;0.00127338451304409!GO:0043492;ATPase activity, coupled to movement of substances;0.00131589616219927!GO:0006405;RNA export from nucleus;0.00131926072809594!GO:0031988;membrane-bound vesicle;0.00133770980089664!GO:0035258;steroid hormone receptor binding;0.00136685211451029!GO:0007052;mitotic spindle organization and biogenesis;0.00137408124057861!GO:0006611;protein export from nucleus;0.00139875409811302!GO:0015992;proton transport;0.00146017101868719!GO:0044262;cellular carbohydrate metabolic process;0.00147134648578493!GO:0016893;endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00149885241796972!GO:0009116;nucleoside metabolic process;0.00153553860112381!GO:0000049;tRNA binding;0.00154793434693358!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00156620871082416!GO:0006767;water-soluble vitamin metabolic process;0.00164141589807034!GO:0048500;signal recognition particle;0.00164296668644619!GO:0006505;GPI anchor metabolic process;0.00165200868309207!GO:0008312;7S RNA binding;0.0016601424781416!GO:0009451;RNA modification;0.00166817655469368!GO:0048487;beta-tubulin binding;0.00166817655469368!GO:0016796;exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters;0.00168306831874896!GO:0051252;regulation of RNA metabolic process;0.00168306831874896!GO:0006818;hydrogen transport;0.00175700388635036!GO:0030384;phosphoinositide metabolic process;0.00182474170568843!GO:0008180;signalosome;0.00186785752909132!GO:0006401;RNA catabolic process;0.00190441440980184!GO:0007093;mitotic cell cycle checkpoint;0.00192296437801606!GO:0008320;protein transmembrane transporter activity;0.00194147259109511!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00212732270076786!GO:0016023;cytoplasmic membrane-bound vesicle;0.00215806054545468!GO:0016628;oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor;0.00217124202521056!GO:0016481;negative regulation of transcription;0.00217863177443701!GO:0006270;DNA replication initiation;0.00221158178648599!GO:0043601;nuclear replisome;0.00221158178648599!GO:0030894;replisome;0.00221158178648599!GO:0006118;electron transport;0.00221856980449629!GO:0006007;glucose catabolic process;0.00221856980449629!GO:0005905;coated pit;0.00221856980449629!GO:0006497;protein amino acid lipidation;0.00222813356196497!GO:0005876;spindle microtubule;0.00226395433411096!GO:0005758;mitochondrial intermembrane space;0.00232314903475037!GO:0030663;COPI coated vesicle membrane;0.00235760314510227!GO:0030126;COPI vesicle coat;0.00235760314510227!GO:0003714;transcription corepressor activity;0.00240240040001878!GO:0000086;G2/M transition of mitotic cell cycle;0.00245854430882795!GO:0006268;DNA unwinding during replication;0.00249797591382894!GO:0000178;exosome (RNase complex);0.00259534835108489!GO:0006733;oxidoreduction coenzyme metabolic process;0.00262568479396848!GO:0048522;positive regulation of cellular process;0.002734504935007!GO:0000228;nuclear chromosome;0.00273513656882997!GO:0003746;translation elongation factor activity;0.00284876580508551!GO:0032561;guanyl ribonucleotide binding;0.00300640431724316!GO:0019001;guanyl nucleotide binding;0.00300640431724316!GO:0016272;prefoldin complex;0.00302803298129904!GO:0008632;apoptotic program;0.00303349852159424!GO:0008408;3'-5' exonuclease activity;0.00316499822122161!GO:0016281;eukaryotic translation initiation factor 4F complex;0.00330578373265263!GO:0016044;membrane organization and biogenesis;0.00338382553999253!GO:0006144;purine base metabolic process;0.00338382553999253!GO:0006352;transcription initiation;0.0034335199389621!GO:0004532;exoribonuclease activity;0.00343815832480763!GO:0016896;exoribonuclease activity, producing 5'-phosphomonoesters;0.00343815832480763!GO:0042770;DNA damage response, signal transduction;0.00352675030385236!GO:0022884;macromolecule transmembrane transporter activity;0.00381334650838467!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.00381334650838467!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00382089301382747!GO:0045047;protein targeting to ER;0.00382089301382747!GO:0005769;early endosome;0.00387960744223502!GO:0005637;nuclear inner membrane;0.00398414616095041!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00410571967766887!GO:0000139;Golgi membrane;0.00426825130944646!GO:0042393;histone binding;0.0044239626663658!GO:0006595;polyamine metabolic process;0.00448697319265273!GO:0006402;mRNA catabolic process;0.004547575493434!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00474014439940962!GO:0015002;heme-copper terminal oxidase activity;0.00474014439940962!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00474014439940962!GO:0004129;cytochrome-c oxidase activity;0.00474014439940962!GO:0022890;inorganic cation transmembrane transporter activity;0.00474758126640115!GO:0006519;amino acid and derivative metabolic process;0.00476896770271657!GO:0000096;sulfur amino acid metabolic process;0.00487932809689016!GO:0006891;intra-Golgi vesicle-mediated transport;0.0048849073936357!GO:0030118;clathrin coat;0.00515476683316052!GO:0006400;tRNA modification;0.00520722268627854!GO:0007243;protein kinase cascade;0.00524643614806027!GO:0030137;COPI-coated vesicle;0.00531204041228132!GO:0040008;regulation of growth;0.00562840738596203!GO:0008757;S-adenosylmethionine-dependent methyltransferase activity;0.00565738006076262!GO:0016408;C-acyltransferase activity;0.00581201946498338!GO:0043065;positive regulation of apoptosis;0.00588247636245337!GO:0045792;negative regulation of cell size;0.00624016986251611!GO:0007010;cytoskeleton organization and biogenesis;0.00642539580714959!GO:0004526;ribonuclease P activity;0.00645293340824409!GO:0031982;vesicle;0.00645616008410269!GO:0008022;protein C-terminus binding;0.00679211345981!GO:0000287;magnesium ion binding;0.00693597446180812!GO:0007007;inner mitochondrial membrane organization and biogenesis;0.00696634450302878!GO:0030308;negative regulation of cell growth;0.00698149015875685!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00705130903255043!GO:0046983;protein dimerization activity;0.00717797415820869!GO:0004549;tRNA-specific ribonuclease activity;0.00724087772114479!GO:0008637;apoptotic mitochondrial changes;0.00726820206617087!GO:0008139;nuclear localization sequence binding;0.00727104764356261!GO:0043068;positive regulation of programmed cell death;0.00729642189026292!GO:0031970;organelle envelope lumen;0.00742620414315295!GO:0050790;regulation of catalytic activity;0.00757385397621865!GO:0043624;cellular protein complex disassembly;0.00773759227189028!GO:0051338;regulation of transferase activity;0.00780279879442284!GO:0004003;ATP-dependent DNA helicase activity;0.00780279879442284!GO:0050794;regulation of cellular process;0.00785380938717241!GO:0043154;negative regulation of caspase activity;0.00788529379169317!GO:0019899;enzyme binding;0.00806200803815308!GO:0046982;protein heterodimerization activity;0.00825917361208404!GO:0006509;membrane protein ectodomain proteolysis;0.00837338520493416!GO:0033619;membrane protein proteolysis;0.00837338520493416!GO:0042158;lipoprotein biosynthetic process;0.00854768696258938!GO:0032259;methylation;0.00868539873981123!GO:0031124;mRNA 3'-end processing;0.00892164748346509!GO:0007050;cell cycle arrest;0.00897443230449013!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00905339052397308!GO:0043022;ribosome binding;0.00907477350672076!GO:0009124;nucleoside monophosphate biosynthetic process;0.00907477350672076!GO:0009123;nucleoside monophosphate metabolic process;0.00907477350672076!GO:0000339;RNA cap binding;0.00907477350672076!GO:0008629;induction of apoptosis by intracellular signals;0.00913346607130153!GO:0003725;double-stranded RNA binding;0.00920294910055076!GO:0005832;chaperonin-containing T-complex;0.00938448182292967!GO:0016251;general RNA polymerase II transcription factor activity;0.00943423963463156!GO:0030658;transport vesicle membrane;0.00959108895583642!GO:0015631;tubulin binding;0.0095987902700528!GO:0046966;thyroid hormone receptor binding;0.0095987902700528!GO:0043488;regulation of mRNA stability;0.00965833059003453!GO:0043487;regulation of RNA stability;0.00965833059003453!GO:0006289;nucleotide-excision repair;0.00999385631948495!GO:0009303;rRNA transcription;0.0102078803449458!GO:0043549;regulation of kinase activity;0.010337139612253!GO:0000175;3'-5'-exoribonuclease activity;0.0104057601888962!GO:0031410;cytoplasmic vesicle;0.0104916538507026!GO:0031570;DNA integrity checkpoint;0.0104916538507026!GO:0043414;biopolymer methylation;0.0105739039030232!GO:0051539;4 iron, 4 sulfur cluster binding;0.0106838883880157!GO:0000922;spindle pole;0.0109286036827208!GO:0031902;late endosome membrane;0.0112660274621743!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0114757027548551!GO:0009119;ribonucleoside metabolic process;0.0118098199330285!GO:0043433;negative regulation of transcription factor activity;0.0121204053996927!GO:0005744;mitochondrial inner membrane presequence translocase complex;0.01220766540709!GO:0005874;microtubule;0.0122260307476337!GO:0042719;mitochondrial intermembrane space protein transporter complex;0.0122762388086839!GO:0045039;protein import into mitochondrial inner membrane;0.0122762388086839!GO:0016616;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor;0.012461748830904!GO:0006807;nitrogen compound metabolic process;0.0125743627258598!GO:0004540;ribonuclease activity;0.0125743627258598!GO:0005862;muscle thin filament tropomyosin;0.012687602988839!GO:0030659;cytoplasmic vesicle membrane;0.0127282070908347!GO:0016125;sterol metabolic process;0.0127833737636839!GO:0006778;porphyrin metabolic process;0.0131076387309398!GO:0033013;tetrapyrrole metabolic process;0.0131076387309398!GO:0008652;amino acid biosynthetic process;0.0131076387309398!GO:0030521;androgen receptor signaling pathway;0.0132642020336688!GO:0007021;tubulin folding;0.0133457453855284!GO:0006740;NADPH regeneration;0.0142008424009772!GO:0006098;pentose-phosphate shunt;0.0142008424009772!GO:0016407;acetyltransferase activity;0.0142248256611762!GO:0004523;ribonuclease H activity;0.0142248256611762!GO:0030125;clathrin vesicle coat;0.0144653010450279!GO:0030665;clathrin coated vesicle membrane;0.0144653010450279!GO:0006096;glycolysis;0.0146717654109841!GO:0000725;recombinational repair;0.0149612213622481!GO:0000724;double-strand break repair via homologous recombination;0.0149612213622481!GO:0044454;nuclear chromosome part;0.0150934601446083!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.0151834867052049!GO:0032984;macromolecular complex disassembly;0.0157398183467118!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0160293813008894!GO:0016614;oxidoreductase activity, acting on CH-OH group of donors;0.0160293813008894!GO:0006338;chromatin remodeling;0.0161125797055985!GO:0045859;regulation of protein kinase activity;0.0163393856550318!GO:0006417;regulation of translation;0.0166859178031346!GO:0007017;microtubule-based process;0.017107706557382!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0173533097523331!GO:0050681;androgen receptor binding;0.0173533097523331!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0173533097523331!GO:0005869;dynactin complex;0.0180045577625112!GO:0030119;AP-type membrane coat adaptor complex;0.0180523775614733!GO:0007034;vacuolar transport;0.0185416745366694!GO:0006378;mRNA polyadenylation;0.0189360694124247!GO:0044255;cellular lipid metabolic process;0.019439006356624!GO:0048144;fibroblast proliferation;0.0197581936289499!GO:0048145;regulation of fibroblast proliferation;0.0197581936289499!GO:0006066;alcohol metabolic process;0.0202563886332249!GO:0009161;ribonucleoside monophosphate metabolic process;0.0203424582612672!GO:0009156;ribonucleoside monophosphate biosynthetic process;0.0203424582612672!GO:0046365;monosaccharide catabolic process;0.0204058536715772!GO:0006769;nicotinamide metabolic process;0.0204335313629044!GO:0043241;protein complex disassembly;0.0209848072067395!GO:0016197;endosome transport;0.0212569315861839!GO:0048146;positive regulation of fibroblast proliferation;0.021269618522533!GO:0000070;mitotic sister chromatid segregation;0.0213495161624309!GO:0045045;secretory pathway;0.0215722850372208!GO:0006541;glutamine metabolic process;0.0216205393168591!GO:0031529;ruffle organization and biogenesis;0.0216556695877928!GO:0008538;proteasome activator activity;0.0220987486950143!GO:0006360;transcription from RNA polymerase I promoter;0.0224402239716688!GO:0005732;small nucleolar ribonucleoprotein complex;0.022442679538375!GO:0030660;Golgi-associated vesicle membrane;0.022489733018784!GO:0009308;amine metabolic process;0.0225967817327273!GO:0050178;phenylpyruvate tautomerase activity;0.0227047578248414!GO:0005996;monosaccharide metabolic process;0.0227113747446065!GO:0005853;eukaryotic translation elongation factor 1 complex;0.0227113747446065!GO:0030131;clathrin adaptor complex;0.0233197671177913!GO:0046164;alcohol catabolic process;0.0233748873769793!GO:0044438;microbody part;0.0234858711052811!GO:0044439;peroxisomal part;0.0234858711052811!GO:0005663;DNA replication factor C complex;0.0235919017638909!GO:0008092;cytoskeletal protein binding;0.0236438517342911!GO:0006643;membrane lipid metabolic process;0.0236438517342911!GO:0000792;heterochromatin;0.0238129026622889!GO:0006979;response to oxidative stress;0.0238129026622889!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0238129026622889!GO:0010257;NADH dehydrogenase complex assembly;0.0238129026622889!GO:0033108;mitochondrial respiratory chain complex assembly;0.0238129026622889!GO:0030508;thiol-disulfide exchange intermediate activity;0.0241278507177189!GO:0005774;vacuolar membrane;0.0242136789415413!GO:0008250;oligosaccharyl transferase complex;0.0242824387154812!GO:0003923;GPI-anchor transamidase activity;0.0242824387154812!GO:0016255;attachment of GPI anchor to protein;0.0242824387154812!GO:0042765;GPI-anchor transamidase complex;0.0242824387154812!GO:0000819;sister chromatid segregation;0.0242824387154812!GO:0000030;mannosyltransferase activity;0.0243560121100601!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0243560121100601!GO:0031227;intrinsic to endoplasmic reticulum membrane;0.0243760699267825!GO:0019318;hexose metabolic process;0.0243877545732033!GO:0004576;oligosaccharyl transferase activity;0.0248280050506452!GO:0012506;vesicle membrane;0.0250857337255657!GO:0051059;NF-kappaB binding;0.0251006181676797!GO:0007346;regulation of progression through mitotic cell cycle;0.0252598243802929!GO:0009003;signal peptidase activity;0.0256647000383193!GO:0004659;prenyltransferase activity;0.0256647000383193!GO:0006730;one-carbon compound metabolic process;0.0259269949151036!GO:0003702;RNA polymerase II transcription factor activity;0.0259269949151036!GO:0006779;porphyrin biosynthetic process;0.0264122908267893!GO:0033014;tetrapyrrole biosynthetic process;0.0264122908267893!GO:0017166;vinculin binding;0.0266344978365317!GO:0008234;cysteine-type peptidase activity;0.0266344978365317!GO:0006354;RNA elongation;0.0266344978365317!GO:0050811;GABA receptor binding;0.027191954469264!GO:0044433;cytoplasmic vesicle part;0.0274817431955331!GO:0022411;cellular component disassembly;0.0284119635809023!GO:0045926;negative regulation of growth;0.0287156609990475!GO:0031123;RNA 3'-end processing;0.0291391372781479!GO:0006006;glucose metabolic process;0.0291391372781479!GO:0005669;transcription factor TFIID complex;0.0292285800530722!GO:0000726;non-recombinational repair;0.0295550182205051!GO:0004860;protein kinase inhibitor activity;0.0296289920363409!GO:0046519;sphingoid metabolic process;0.0296289920363409!GO:0000152;nuclear ubiquitin ligase complex;0.0296289920363409!GO:0016788;hydrolase activity, acting on ester bonds;0.0299679209289366!GO:0001836;release of cytochrome c from mitochondria;0.0304847177406883!GO:0006220;pyrimidine nucleotide metabolic process;0.0307310329513533!GO:0006213;pyrimidine nucleoside metabolic process;0.030820984520778!GO:0015036;disulfide oxidoreductase activity;0.0309748906982708!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.0310273511546392!GO:0004861;cyclin-dependent protein kinase inhibitor activity;0.031283991273309!GO:0019320;hexose catabolic process;0.0316362232517672!GO:0006376;mRNA splice site selection;0.0318671461646252!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0318671461646252!GO:0031406;carboxylic acid binding;0.0320052598871581!GO:0030134;ER to Golgi transport vesicle;0.0320571426241231!GO:0008536;Ran GTPase binding;0.0322181769229775!GO:0051053;negative regulation of DNA metabolic process;0.0324361604067367!GO:0006596;polyamine biosynthetic process;0.032479875462204!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.0327607264625043!GO:0031903;microbody membrane;0.0328684472928262!GO:0005778;peroxisomal membrane;0.0328684472928262!GO:0031326;regulation of cellular biosynthetic process;0.0328684472928262!GO:0005658;alpha DNA polymerase:primase complex;0.0329427285436825!GO:0043189;H4/H2A histone acetyltransferase complex;0.0334239268262455!GO:0042168;heme metabolic process;0.0339563800046561!GO:0030677;ribonuclease P complex;0.0348610725651686!GO:0019362;pyridine nucleotide metabolic process;0.0348709095164167!GO:0046112;nucleobase biosynthetic process;0.0348752262648416!GO:0040029;regulation of gene expression, epigenetic;0.0349558953392781!GO:0009889;regulation of biosynthetic process;0.0351400767409558!GO:0046128;purine ribonucleoside metabolic process;0.0351400767409558!GO:0042278;purine nucleoside metabolic process;0.0351400767409558!GO:0005850;eukaryotic translation initiation factor 2 complex;0.0352315208217126!GO:0045893;positive regulation of transcription, DNA-dependent;0.0354976455291572!GO:0016790;thiolester hydrolase activity;0.0359364945891703!GO:0042364;water-soluble vitamin biosynthetic process;0.0359364945891703!GO:0006356;regulation of transcription from RNA polymerase I promoter;0.0366228988026288!GO:0005784;translocon complex;0.0367621381258097!GO:0007040;lysosome organization and biogenesis;0.0369940489423157!GO:0006672;ceramide metabolic process;0.037487473421949!GO:0009967;positive regulation of signal transduction;0.0377426711968135!GO:0006739;NADP metabolic process;0.0381705069373709!GO:0045936;negative regulation of phosphate metabolic process;0.038586492801042!GO:0030127;COPII vesicle coat;0.0388748384233943!GO:0012507;ER to Golgi transport vesicle membrane;0.0388748384233943!GO:0003857;3-hydroxyacyl-CoA dehydrogenase activity;0.0393939156468534!GO:0000077;DNA damage checkpoint;0.0394508621397222!GO:0000781;chromosome, telomeric region;0.0395581345456996!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0396699317213264!GO:0031577;spindle checkpoint;0.0399768377666409!GO:0047485;protein N-terminus binding;0.0400353834437214!GO:0019783;small conjugating protein-specific protease activity;0.0401870776361318!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.040419906953476!GO:0007033;vacuole organization and biogenesis;0.0408231034973941!GO:0051716;cellular response to stimulus;0.0410194330873315!GO:0032200;telomere organization and biogenesis;0.0410774171266347!GO:0000723;telomere maintenance;0.0410774171266347!GO:0019206;nucleoside kinase activity;0.0411863271268845!GO:0001522;pseudouridine synthesis;0.0418063745606424!GO:0006749;glutathione metabolic process;0.0420851651120267!GO:0004448;isocitrate dehydrogenase activity;0.0422490758194396!GO:0001726;ruffle;0.0422680843269744!GO:0031371;ubiquitin conjugating enzyme complex;0.0425720057406857!GO:0042769;DNA damage response, detection of DNA damage;0.0428098257478529!GO:0003985;acetyl-CoA C-acetyltransferase activity;0.0428098257478529!GO:0006644;phospholipid metabolic process;0.043049839289257!GO:0016417;S-acyltransferase activity;0.0432796397341155!GO:0030036;actin cytoskeleton organization and biogenesis;0.0436567131415209!GO:0030503;regulation of cell redox homeostasis;0.044590605684456!GO:0016584;nucleosome positioning;0.044604805124017!GO:0051128;regulation of cellular component organization and biogenesis;0.044604805124017!GO:0008426;protein kinase C inhibitor activity;0.0448282663031897!GO:0007041;lysosomal transport;0.0448732442842088!GO:0030433;ER-associated protein catabolic process;0.0450007368223252!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0450007368223252!GO:0035267;NuA4 histone acetyltransferase complex;0.0453052842541284!GO:0030032;lamellipodium biogenesis;0.0456797677671032!GO:0030911;TPR domain binding;0.0457828264824753!GO:0048468;cell development;0.0459854542200608!GO:0031625;ubiquitin protein ligase binding;0.04628337685683!GO:0008173;RNA methyltransferase activity;0.0464201974758789!GO:0003988;acetyl-CoA C-acyltransferase activity;0.0464358659448054!GO:0009225;nucleotide-sugar metabolic process;0.0465752604574887!GO:0030133;transport vesicle;0.0466532864899238!GO:0005971;ribonucleoside-diphosphate reductase complex;0.0466556103777191!GO:0009066;aspartate family amino acid metabolic process;0.0466556103777191!GO:0051098;regulation of binding;0.0466824765143521!GO:0004843;ubiquitin-specific protease activity;0.0469786778808764!GO:0008017;microtubule binding;0.0469810581015635!GO:0044437;vacuolar part;0.0470466418762347!GO:0030027;lamellipodium;0.0470466418762347!GO:0003756;protein disulfide isomerase activity;0.047225707645058!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.047225707645058!GO:0030515;snoRNA binding;0.0474763067714868!GO:0033673;negative regulation of kinase activity;0.0483240877819122!GO:0006469;negative regulation of protein kinase activity;0.0483240877819122!GO:0018196;peptidyl-asparagine modification;0.0497230207508157!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.0497230207508157 | |||
|sample_id=11890 | |sample_id=11890 | ||
|sample_note= | |sample_note= | ||
Line 75: | Line 99: | ||
|sample_tissue= | |sample_tissue= | ||
|top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.89400581176;ESRRA:1.64419028066;HES1:1.61991592335;E2F1..5:1.54452079242;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.48480123071;ELK1,4_GABP{A,B1}:1.33214211508;PPARG:1.32320136262;HIF1A:1.31244522114;FOXM1:1.30568276922;NR5A1,2:1.30323152331;FOXD3:1.09443030765;NKX3-1:1.03607607731;FOXQ1:1.03090354501;PAX1,9:0.985842380874;YY1:0.980658611622;ARID5B:0.919320901096;bHLH_family:0.839796006458;NR6A1:0.813151853557;HOX{A6,A7,B6,B7}:0.801039034278;NRF1:0.785528322811;ZNF143:0.754594188136;TBX4,5:0.732668903416;HNF4A_NR2F1,2:0.706847073217;PAX8:0.692759805937;GCM1,2:0.644878958255;NFY{A,B,C}:0.642003539648;NKX3-2:0.630620212682;PAX5:0.611960553981;FOXN1:0.608143196564;SNAI1..3:0.59582184052;UFEwm:0.561702941682;MYB:0.551166815486;NFE2L1:0.541766026207;RXR{A,B,G}:0.524592997645;POU1F1:0.496034047018;TEAD1:0.495622226964;ZEB1:0.459261796273;IKZF1:0.390974562014;EP300:0.365685550124;ZNF148:0.339031699069;TP53:0.327916544174;TEF:0.322342409797;IRF7:0.313660038578;TFDP1:0.260785961297;GFI1:0.242280744773;MYBL2:0.236247597457;IKZF2:0.205060594345;ALX4:0.204249819035;GTF2A1,2:0.191709985352;PITX1..3:0.181160186736;PAX2:0.146631678824;NKX6-1,2:0.140461288905;CREB1:0.135792838633;HOXA9_MEIS1:0.121846937655;GFI1B:0.11626766657;ZNF423:0.114668450975;RFX2..5_RFXANK_RFXAP:0.111262617576;MYOD1:0.0987964491269;LEF1_TCF7_TCF7L1,2:0.072586900375;POU3F1..4:0.0619554322531;HSF1,2:0.0607206738984;ZBTB16:0.0404033167058;SOX{8,9,10}:0.0316500591943;NFE2:0.0275713240079;ZNF384:0.0209110712231;BREu{core}:0.0155061046241;LHX3,4:0.0133811556078;ONECUT1,2:0.0131675513553;OCT4_SOX2{dimer}:0.00921773026692;BACH2:0.00793033518352;CDC5L:0.00770064723743;MTF1:0.00399551202757;HLF:-0.00103051220822;FOXL1:-0.0104014153389;HOX{A5,B5}:-0.0182066928751;HNF1A:-0.0322573069513;CUX2:-0.0349415138473;ATF5_CREB3:-0.0439957304538;CEBPA,B_DDIT3:-0.0551737775794;GZF1:-0.0559845447646;NR3C1:-0.0714739626494;POU2F1..3:-0.071878708078;NFE2L2:-0.0750757298129;VSX1,2:-0.0752979883373;FOS_FOS{B,L1}_JUN{B,D}:-0.0981938607659;HOX{A4,D4}:-0.101559656729;NKX2-2,8:-0.114926580575;TBP:-0.115934172849;FOX{F1,F2,J1}:-0.11998974529;CDX1,2,4:-0.130703670031;ZBTB6:-0.147146701894;RORA:-0.148235867739;TLX1..3_NFIC{dimer}:-0.149824642735;PAX3,7:-0.174547671154;STAT5{A,B}:-0.186453181277;PDX1:-0.189497056604;DBP:-0.194451163414;HMGA1,2:-0.201485434729;ELF1,2,4:-0.202235509184;TFCP2:-0.206821237527;ESR1:-0.20822039755;FOX{I1,J2}:-0.215732108661;HAND1,2:-0.223810403048;GLI1..3:-0.230146437491;STAT2,4,6:-0.233302324613;ATF4:-0.234806724128;MAFB:-0.238175867353;MEF2{A,B,C,D}:-0.246914765249;EBF1:-0.248311118334;AIRE:-0.269205932232;PAX4:-0.269230459788;AHR_ARNT_ARNT2:-0.277254939929;BPTF:-0.278804349581;LMO2:-0.29250530234;NFKB1_REL_RELA:-0.293216452152;NFIL3:-0.317102132899;PBX1:-0.334111736376;EVI1:-0.339698533129;KLF4:-0.350286047515;IRF1,2:-0.353644617864;PRRX1,2:-0.353933886672;T:-0.361789769579;FOXP3:-0.363797003838;RXRA_VDR{dimer}:-0.37597839135;FOSL2:-0.386097448138;JUN:-0.400035097143;EN1,2:-0.411264568073;FOXP1:-0.415934217248;PAX6:-0.422962416444;CRX:-0.437763397037;TFAP2{A,C}:-0.448966723708;SREBF1,2:-0.454411053914;NR1H4:-0.454432337331;HIC1:-0.457358686114;SPIB:-0.469586735929;HBP1_HMGB_SSRP1_UBTF:-0.474314824532;GTF2I:-0.492600460092;ATF6:-0.5004469243;TFAP2B:-0.511585743089;ZIC1..3:-0.518829887294;POU5F1:-0.525218900871;ZFP161:-0.53809073541;RFX1:-0.547582166662;NKX2-1,4:-0.554449648609;SRF:-0.607013272805;ALX1:-0.610620641349;SOX2:-0.619303244066;SP1:-0.620517804145;SPI1:-0.623461913655;SOX5:-0.679744164475;NANOG:-0.681369952098;GATA6:-0.682120035916;RBPJ:-0.682789049217;NKX2-3_NKX2-5:-0.686914287184;ADNP_IRX_SIX_ZHX:-0.694371612287;TFAP4:-0.694852311382;MED-1{core}:-0.698443951993;RUNX1..3:-0.707504491496;ZNF238:-0.729674489277;EGR1..3:-0.737178878338;REST:-0.737849809722;NHLH1,2:-0.754069184083;MTE{core}:-0.760754692334;ETS1,2:-0.782783917957;FOXA2:-0.789080380791;GATA4:-0.81324956381;TOPORS:-0.826024620265;XCPE1{core}:-0.832254377855;TAL1_TCF{3,4,12}:-0.840877437855;SOX17:-0.842282151243;AR:-0.847672028844;POU6F1:-0.864002632481;STAT1,3:-0.864534231273;RREB1:-0.866522061305;DMAP1_NCOR{1,2}_SMARC:-0.886005812972;NFATC1..3:-0.926287565522;MAZ:-0.935716256316;MYFfamily:-1.04127352135;FOXO1,3,4:-1.05455466851;PRDM1:-1.09948963615;ATF2:-1.10347217506;MZF1:-1.15379667387;FOX{D1,D2}:-1.17562065394;SMAD1..7,9:-1.19639917812;TLX2:-1.25981066722;PATZ1:-1.2644220747;XBP1:-1.29670309097;TGIF1:-1.34122959731;NFIX:-1.35101569454;HMX1:-1.35183616903;NANOG{mouse}:-1.45660690236;SPZ1:-1.71535145399 | |top_motifs=ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.89400581176;ESRRA:1.64419028066;HES1:1.61991592335;E2F1..5:1.54452079242;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.48480123071;ELK1,4_GABP{A,B1}:1.33214211508;PPARG:1.32320136262;HIF1A:1.31244522114;FOXM1:1.30568276922;NR5A1,2:1.30323152331;FOXD3:1.09443030765;NKX3-1:1.03607607731;FOXQ1:1.03090354501;PAX1,9:0.985842380874;YY1:0.980658611622;ARID5B:0.919320901096;bHLH_family:0.839796006458;NR6A1:0.813151853557;HOX{A6,A7,B6,B7}:0.801039034278;NRF1:0.785528322811;ZNF143:0.754594188136;TBX4,5:0.732668903416;HNF4A_NR2F1,2:0.706847073217;PAX8:0.692759805937;GCM1,2:0.644878958255;NFY{A,B,C}:0.642003539648;NKX3-2:0.630620212682;PAX5:0.611960553981;FOXN1:0.608143196564;SNAI1..3:0.59582184052;UFEwm:0.561702941682;MYB:0.551166815486;NFE2L1:0.541766026207;RXR{A,B,G}:0.524592997645;POU1F1:0.496034047018;TEAD1:0.495622226964;ZEB1:0.459261796273;IKZF1:0.390974562014;EP300:0.365685550124;ZNF148:0.339031699069;TP53:0.327916544174;TEF:0.322342409797;IRF7:0.313660038578;TFDP1:0.260785961297;GFI1:0.242280744773;MYBL2:0.236247597457;IKZF2:0.205060594345;ALX4:0.204249819035;GTF2A1,2:0.191709985352;PITX1..3:0.181160186736;PAX2:0.146631678824;NKX6-1,2:0.140461288905;CREB1:0.135792838633;HOXA9_MEIS1:0.121846937655;GFI1B:0.11626766657;ZNF423:0.114668450975;RFX2..5_RFXANK_RFXAP:0.111262617576;MYOD1:0.0987964491269;LEF1_TCF7_TCF7L1,2:0.072586900375;POU3F1..4:0.0619554322531;HSF1,2:0.0607206738984;ZBTB16:0.0404033167058;SOX{8,9,10}:0.0316500591943;NFE2:0.0275713240079;ZNF384:0.0209110712231;BREu{core}:0.0155061046241;LHX3,4:0.0133811556078;ONECUT1,2:0.0131675513553;OCT4_SOX2{dimer}:0.00921773026692;BACH2:0.00793033518352;CDC5L:0.00770064723743;MTF1:0.00399551202757;HLF:-0.00103051220822;FOXL1:-0.0104014153389;HOX{A5,B5}:-0.0182066928751;HNF1A:-0.0322573069513;CUX2:-0.0349415138473;ATF5_CREB3:-0.0439957304538;CEBPA,B_DDIT3:-0.0551737775794;GZF1:-0.0559845447646;NR3C1:-0.0714739626494;POU2F1..3:-0.071878708078;NFE2L2:-0.0750757298129;VSX1,2:-0.0752979883373;FOS_FOS{B,L1}_JUN{B,D}:-0.0981938607659;HOX{A4,D4}:-0.101559656729;NKX2-2,8:-0.114926580575;TBP:-0.115934172849;FOX{F1,F2,J1}:-0.11998974529;CDX1,2,4:-0.130703670031;ZBTB6:-0.147146701894;RORA:-0.148235867739;TLX1..3_NFIC{dimer}:-0.149824642735;PAX3,7:-0.174547671154;STAT5{A,B}:-0.186453181277;PDX1:-0.189497056604;DBP:-0.194451163414;HMGA1,2:-0.201485434729;ELF1,2,4:-0.202235509184;TFCP2:-0.206821237527;ESR1:-0.20822039755;FOX{I1,J2}:-0.215732108661;HAND1,2:-0.223810403048;GLI1..3:-0.230146437491;STAT2,4,6:-0.233302324613;ATF4:-0.234806724128;MAFB:-0.238175867353;MEF2{A,B,C,D}:-0.246914765249;EBF1:-0.248311118334;AIRE:-0.269205932232;PAX4:-0.269230459788;AHR_ARNT_ARNT2:-0.277254939929;BPTF:-0.278804349581;LMO2:-0.29250530234;NFKB1_REL_RELA:-0.293216452152;NFIL3:-0.317102132899;PBX1:-0.334111736376;EVI1:-0.339698533129;KLF4:-0.350286047515;IRF1,2:-0.353644617864;PRRX1,2:-0.353933886672;T:-0.361789769579;FOXP3:-0.363797003838;RXRA_VDR{dimer}:-0.37597839135;FOSL2:-0.386097448138;JUN:-0.400035097143;EN1,2:-0.411264568073;FOXP1:-0.415934217248;PAX6:-0.422962416444;CRX:-0.437763397037;TFAP2{A,C}:-0.448966723708;SREBF1,2:-0.454411053914;NR1H4:-0.454432337331;HIC1:-0.457358686114;SPIB:-0.469586735929;HBP1_HMGB_SSRP1_UBTF:-0.474314824532;GTF2I:-0.492600460092;ATF6:-0.5004469243;TFAP2B:-0.511585743089;ZIC1..3:-0.518829887294;POU5F1:-0.525218900871;ZFP161:-0.53809073541;RFX1:-0.547582166662;NKX2-1,4:-0.554449648609;SRF:-0.607013272805;ALX1:-0.610620641349;SOX2:-0.619303244066;SP1:-0.620517804145;SPI1:-0.623461913655;SOX5:-0.679744164475;NANOG:-0.681369952098;GATA6:-0.682120035916;RBPJ:-0.682789049217;NKX2-3_NKX2-5:-0.686914287184;ADNP_IRX_SIX_ZHX:-0.694371612287;TFAP4:-0.694852311382;MED-1{core}:-0.698443951993;RUNX1..3:-0.707504491496;ZNF238:-0.729674489277;EGR1..3:-0.737178878338;REST:-0.737849809722;NHLH1,2:-0.754069184083;MTE{core}:-0.760754692334;ETS1,2:-0.782783917957;FOXA2:-0.789080380791;GATA4:-0.81324956381;TOPORS:-0.826024620265;XCPE1{core}:-0.832254377855;TAL1_TCF{3,4,12}:-0.840877437855;SOX17:-0.842282151243;AR:-0.847672028844;POU6F1:-0.864002632481;STAT1,3:-0.864534231273;RREB1:-0.866522061305;DMAP1_NCOR{1,2}_SMARC:-0.886005812972;NFATC1..3:-0.926287565522;MAZ:-0.935716256316;MYFfamily:-1.04127352135;FOXO1,3,4:-1.05455466851;PRDM1:-1.09948963615;ATF2:-1.10347217506;MZF1:-1.15379667387;FOX{D1,D2}:-1.17562065394;SMAD1..7,9:-1.19639917812;TLX2:-1.25981066722;PATZ1:-1.2644220747;XBP1:-1.29670309097;TGIF1:-1.34122959731;NFIX:-1.35101569454;HMX1:-1.35183616903;NANOG{mouse}:-1.45660690236;SPZ1:-1.71535145399 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:11890-125D9;search_select_hide=table117:FF:11890-125D9 | |||
}} | }} |
Latest revision as of 18:27, 4 June 2020
Name: | Hep-2 cells treated with Streptococci strain 5448, biol_rep1 |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13477 |
Sample type: | cell lines |
Genomic View: | UCSC |
RefEX: | Specific genes |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13477
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13477
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.0941 |
10 | 10 | 0.0621 |
100 | 100 | 0.0249 |
101 | 101 | 0.231 |
102 | 102 | 0.919 |
103 | 103 | 0.656 |
104 | 104 | 0.938 |
105 | 105 | 0.161 |
106 | 106 | 0.0495 |
107 | 107 | 0.267 |
108 | 108 | 0.822 |
109 | 109 | 8.08662e-4 |
11 | 11 | 0.801 |
110 | 110 | 0.21 |
111 | 111 | 0.82 |
112 | 112 | 0.451 |
113 | 113 | 0.00142 |
114 | 114 | 0.9 |
115 | 115 | 0.529 |
116 | 116 | 0.249 |
117 | 117 | 0.114 |
118 | 118 | 0.0904 |
119 | 119 | 0.61 |
12 | 12 | 0.747 |
120 | 120 | 0.0521 |
121 | 121 | 0.492 |
122 | 122 | 0.21 |
123 | 123 | 0.24 |
124 | 124 | 0.539 |
125 | 125 | 0.915 |
126 | 126 | 0.834 |
127 | 127 | 0.24 |
128 | 128 | 0.00103 |
129 | 129 | 0.281 |
13 | 13 | 6.82471e-5 |
130 | 130 | 0.673 |
131 | 131 | 0.442 |
132 | 132 | 0.398 |
133 | 133 | 0.305 |
134 | 134 | 0.988 |
135 | 135 | 0.0841 |
136 | 136 | 0.00316 |
137 | 137 | 0.281 |
138 | 138 | 0.843 |
139 | 139 | 0.0781 |
14 | 14 | 0.395 |
140 | 140 | 0.345 |
141 | 141 | 0.506 |
142 | 142 | 0.695 |
143 | 143 | 0.166 |
144 | 144 | 0.41 |
145 | 145 | 0.349 |
146 | 146 | 0.515 |
147 | 147 | 0.907 |
148 | 148 | 0.433 |
149 | 149 | 0.71 |
15 | 15 | 0.887 |
150 | 150 | 0.463 |
151 | 151 | 0.733 |
152 | 152 | 0.798 |
153 | 153 | 0.567 |
154 | 154 | 0.435 |
155 | 155 | 0.432 |
156 | 156 | 0.0411 |
157 | 157 | 0.12 |
158 | 158 | 0.142 |
159 | 159 | 0.199 |
16 | 16 | 0.784 |
160 | 160 | 0.387 |
161 | 161 | 0.507 |
162 | 162 | 0.765 |
163 | 163 | 0.273 |
164 | 164 | 0.00858 |
165 | 165 | 0.941 |
166 | 166 | 0.0329 |
167 | 167 | 0.176 |
168 | 168 | 0.347 |
169 | 169 | 0.144 |
17 | 17 | 0.991 |
18 | 18 | 0.156 |
19 | 19 | 0.974 |
2 | 2 | 0.557 |
20 | 20 | 0.0758 |
21 | 21 | 0.256 |
22 | 22 | 0.931 |
23 | 23 | 0.00385 |
24 | 24 | 0.687 |
25 | 25 | 0.365 |
26 | 26 | 0.632 |
27 | 27 | 0.927 |
28 | 28 | 0.858 |
29 | 29 | 0.0168 |
3 | 3 | 0.805 |
30 | 30 | 0.368 |
31 | 31 | 0.579 |
32 | 32 | 0.182 |
33 | 33 | 0.166 |
34 | 34 | 0.232 |
35 | 35 | 0.768 |
36 | 36 | 0.162 |
37 | 37 | 0.197 |
38 | 38 | 0.931 |
39 | 39 | 0.925 |
4 | 4 | 0.196 |
40 | 40 | 0.0172 |
41 | 41 | 0.0958 |
42 | 42 | 0.914 |
43 | 43 | 0.508 |
44 | 44 | 0.0383 |
45 | 45 | 0.179 |
46 | 46 | 0.785 |
47 | 47 | 0.352 |
48 | 48 | 0.44 |
49 | 49 | 0.208 |
5 | 5 | 0.187 |
50 | 50 | 0.855 |
51 | 51 | 0.641 |
52 | 52 | 0.368 |
53 | 53 | 0.138 |
54 | 54 | 0.51 |
55 | 55 | 0.0287 |
56 | 56 | 0.95 |
57 | 57 | 0.623 |
58 | 58 | 0.784 |
59 | 59 | 0.781 |
6 | 6 | 0.539 |
60 | 60 | 0.428 |
61 | 61 | 0.0413 |
62 | 62 | 0.829 |
63 | 63 | 0.492 |
64 | 64 | 0.669 |
65 | 65 | 0.449 |
66 | 66 | 0.748 |
67 | 67 | 0.636 |
68 | 68 | 0.678 |
69 | 69 | 0.843 |
7 | 7 | 0.0484 |
70 | 70 | 0.489 |
71 | 71 | 0.0235 |
72 | 72 | 0.803 |
73 | 73 | 0.214 |
74 | 74 | 0.11 |
75 | 75 | 0.096 |
76 | 76 | 0.177 |
77 | 77 | 0.521 |
78 | 78 | 0.169 |
79 | 79 | 0.894 |
8 | 8 | 0.0954 |
80 | 80 | 0.0333 |
81 | 81 | 0.31 |
82 | 82 | 0.196 |
83 | 83 | 0.544 |
84 | 84 | 0.559 |
85 | 85 | 0.0301 |
86 | 86 | 0.868 |
87 | 87 | 0.00473 |
88 | 88 | 0.751 |
89 | 89 | 0.753 |
9 | 9 | 0.528 |
90 | 90 | 0.0589 |
91 | 91 | 0.0196 |
92 | 92 | 0.0827 |
93 | 93 | 0.349 |
94 | 94 | 0.421 |
95 | 95 | 0.00104 |
96 | 96 | 0.46 |
97 | 97 | 0.742 |
98 | 98 | 0.991 |
99 | 99 | 0.359 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13477
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0011133 human Hep-2 cells treated with Streptococci strain 5448 sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0000066 (epithelial cell)
0000255 (eukaryotic cell)
DOID: Disease
4 (disease)
162 (cancer)
14566 (disease of cellular proliferation)
0050687 (cell type cancer)
305 (carcinoma)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001737 (larynx)
0000064 (organ part)
0004119 (endoderm-derived structure)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000072 (segment of respiratory tract)
0010317 (germ layer / neural crest derived structure)
0000065 (respiratory tract)
0001004 (respiratory system)
0001557 (upper respiratory tract)
FF: FANTOM5
0000102 (sample by type)
0000003 (cell line sample)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000625 (experimental infection sample)
0000350 (experimentally modified sample)
0000632 (group A streptococci treatment sample)
0104978 (HEp-2 cell sample)
0000638 (Streptococcus strain 5448 treatment sample)
0100297 (carcinoma cell line sample)
0101120 (epithelial cell line sample)
0011133 (human Hep-2 cells treated with Streptococci strain 5448 sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0008947 (respiratory primordium)
UBERON:0002532 (epiblast (generic))
UBERON:0006595 (presumptive endoderm)
UBERON:0010316 (germ layer / neural crest)