FF:10182-103D2: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet= | |DRA_sample_Accession=CAGE@SAMD00004969 | ||
|accession_numbers=CAGE;DRX008676;DRR009548;DRZ000973;DRZ002358;DRZ012323;DRZ013708 | |||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0007023,UBERON:0000955,UBERON:0000988,UBERON:0002148,UBERON:0000479,UBERON:0004121,UBERON:0000064,UBERON:0010314,UBERON:0011216,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000063,UBERON:0000481,UBERON:0000073,UBERON:0000477,UBERON:0003528,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0002680,UBERON:0002616,UBERON:0004733,UBERON:0004732,UBERON:0006331,UBERON:0009662,UBERON:0000125,UBERON:0002020,UBERON:0010317,UBERON:0002308,UBERON:0001017,UBERON:0001016,UBERON:0001895,UBERON:0002298,UBERON:0002028 | |||
|ancestors_in_cell_lineage_facet= | |ancestors_in_cell_lineage_facet= | ||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000101,FF:0000001,FF:0000998,FF:0000004,FF:0011487 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|expression_enrichment_score= | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
| Line 35: | Line 42: | ||
|fonse_treatment_closure= | |fonse_treatment_closure= | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/locus%2520coeruleus%2520-%2520adult%252c%2520donor10196.CNhs13808.10182-103D2.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/locus%2520coeruleus%2520-%2520adult%252c%2520donor10196.CNhs13808.10182-103D2.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.tissue.hCAGE/locus%2520coeruleus%2520-%2520adult%252c%2520donor10196.CNhs13808.10182-103D2.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.tissue.hCAGE/locus%2520coeruleus%2520-%2520adult%252c%2520donor10196.CNhs13808.10182-103D2.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.tissue.hCAGE/locus%2520coeruleus%2520-%2520adult%252c%2520donor10196.CNhs13808.10182-103D2.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:10182-103D2 | |id=FF:10182-103D2 | ||
|is_a=FF: | |is_a=FF:0011487 | ||
|is_obsolete= | |||
|library_id=CNhs13808 | |||
|library_id_phase_based=2:CNhs13808 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;10182 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;10182 | |||
|name=locus coeruleus - adult, donor10196 | |name=locus coeruleus - adult, donor10196 | ||
|namespace= | |namespace= | ||
| Line 44: | Line 63: | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq= | |profile_srnaseq= | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=103 | |rna_box=103 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
| Line 57: | Line 79: | ||
|rna_weight_ug=56.1675 | |rna_weight_ug=56.1675 | ||
|sample_age=60 | |sample_age=60 | ||
|sample_category=tissues | |||
|sample_cell_catalog=NA | |sample_cell_catalog=NA | ||
|sample_cell_line= | |sample_cell_line= | ||
| Line 69: | Line 92: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition= | |sample_experimental_condition= | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.2984794918556e-272!GO:0005737;cytoplasm;8.40459757877851e-159!GO:0044444;cytoplasmic part;3.76835726670946e-104!GO:0043226;organelle;4.16390288020146e-101!GO:0043229;intracellular organelle;1.47127063549509e-100!GO:0043227;membrane-bound organelle;5.59890305261127e-92!GO:0043231;intracellular membrane-bound organelle;8.74469971118905e-92!GO:0005515;protein binding;1.58133392291789e-65!GO:0044422;organelle part;1.33376307626583e-64!GO:0044446;intracellular organelle part;1.51853172068648e-63!GO:0032991;macromolecular complex;1.48071013509029e-57!GO:0016043;cellular component organization and biogenesis;1.19288700804972e-46!GO:0005739;mitochondrion;1.67657409593632e-44!GO:0030529;ribonucleoprotein complex;1.12252785780219e-43!GO:0003723;RNA binding;2.92510151179676e-39!GO:0033036;macromolecule localization;3.9429369000193e-37!GO:0015031;protein transport;1.06483805261816e-35!GO:0031090;organelle membrane;6.69504415124304e-35!GO:0008104;protein localization;5.93751726093243e-34!GO:0045184;establishment of protein localization;3.39621945911189e-33!GO:0044429;mitochondrial part;3.63138739378131e-32!GO:0043234;protein complex;1.10899699325112e-30!GO:0046907;intracellular transport;1.3352312462401e-30!GO:0043233;organelle lumen;1.05607428970225e-29!GO:0031974;membrane-enclosed lumen;1.05607428970225e-29!GO:0044238;primary metabolic process;2.86923711083114e-28!GO:0031975;envelope;3.32468664094052e-28!GO:0031967;organelle envelope;4.68234607498936e-28!GO:0044428;nuclear part;6.49346223782601e-28!GO:0044237;cellular metabolic process;6.34915854677647e-27!GO:0005829;cytosol;8.30368260606122e-27!GO:0051649;establishment of cellular localization;1.44351726625304e-26!GO:0051641;cellular localization;1.90010889354157e-26!GO:0016071;mRNA metabolic process;7.21807176374968e-26!GO:0016192;vesicle-mediated transport;5.81543472989684e-25!GO:0005840;ribosome;4.09099181241396e-24!GO:0019538;protein metabolic process;1.31731585784744e-23!GO:0008380;RNA splicing;2.20322389275539e-23!GO:0043170;macromolecule metabolic process;2.55483927355458e-23!GO:0005740;mitochondrial envelope;3.05242623495495e-22!GO:0006396;RNA processing;4.03621201839628e-22!GO:0006886;intracellular protein transport;4.91324593852818e-22!GO:0031966;mitochondrial membrane;8.95720133434436e-22!GO:0006412;translation;1.19225453451241e-21!GO:0006397;mRNA processing;2.40708115992965e-21!GO:0005634;nucleus;2.7656138030846e-21!GO:0044260;cellular macromolecule metabolic process;4.25216796130001e-21!GO:0006119;oxidative phosphorylation;1.00934855696937e-20!GO:0009058;biosynthetic process;1.6795712156977e-20!GO:0019866;organelle inner membrane;3.54036952179971e-20!GO:0044267;cellular protein metabolic process;4.78254501016078e-20!GO:0003735;structural constituent of ribosome;1.1429328677795e-19!GO:0005743;mitochondrial inner membrane;3.34381767560512e-19!GO:0006996;organelle organization and biogenesis;1.18513136854841e-18!GO:0031982;vesicle;1.0173447410894e-17!GO:0005794;Golgi apparatus;1.52913030590777e-17!GO:0033279;ribosomal subunit;1.62039444555711e-17!GO:0000166;nucleotide binding;1.62314212347286e-17!GO:0044249;cellular biosynthetic process;2.1803705052125e-17!GO:0065003;macromolecular complex assembly;6.18295183855135e-17!GO:0031410;cytoplasmic vesicle;6.45977612569571e-17!GO:0005681;spliceosome;2.28978483280175e-16!GO:0044455;mitochondrial membrane part;3.68912628730128e-16!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;4.51499348874766e-16!GO:0009059;macromolecule biosynthetic process;5.18169359228203e-16!GO:0016462;pyrophosphatase activity;5.91646257250599e-16!GO:0031988;membrane-bound vesicle;5.93436739801571e-16!GO:0016817;hydrolase activity, acting on acid anhydrides;6.64637046225435e-16!GO:0031981;nuclear lumen;7.29066942293384e-16!GO:0016023;cytoplasmic membrane-bound vesicle;3.2648195591548e-15!GO:0022607;cellular component assembly;3.57932473517029e-15!GO:0017111;nucleoside-triphosphatase activity;3.83772171734917e-15!GO:0005746;mitochondrial respiratory chain;8.09122238606351e-15!GO:0050136;NADH dehydrogenase (quinone) activity;8.36960341471051e-15!GO:0003954;NADH dehydrogenase activity;8.36960341471051e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;8.36960341471051e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.14912651369503e-14!GO:0012505;endomembrane system;6.68225154760554e-13!GO:0005830;cytosolic ribosome (sensu Eukaryota);1.20827816854686e-12!GO:0044445;cytosolic part;1.21397089364768e-12!GO:0006457;protein folding;1.21397089364768e-12!GO:0030964;NADH dehydrogenase complex (quinone);1.21397089364768e-12!GO:0045271;respiratory chain complex I;1.21397089364768e-12!GO:0005747;mitochondrial respiratory chain complex I;1.21397089364768e-12!GO:0048770;pigment granule;1.21397089364768e-12!GO:0042470;melanosome;1.21397089364768e-12!GO:0031980;mitochondrial lumen;1.42885480346847e-12!GO:0005759;mitochondrial matrix;1.42885480346847e-12!GO:0032553;ribonucleotide binding;1.72303725434432e-12!GO:0032555;purine ribonucleotide binding;1.72303725434432e-12!GO:0042775;organelle ATP synthesis coupled electron transport;3.29789815538478e-12!GO:0042773;ATP synthesis coupled electron transport;3.29789815538478e-12!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;3.62531926753626e-12!GO:0043283;biopolymer metabolic process;3.6307504123872e-12!GO:0022613;ribonucleoprotein complex biogenesis and assembly;5.44544325755354e-12!GO:0016874;ligase activity;6.64994894178895e-12!GO:0017076;purine nucleotide binding;1.02076214447669e-11!GO:0043228;non-membrane-bound organelle;1.06598237043906e-11!GO:0043232;intracellular non-membrane-bound organelle;1.06598237043906e-11!GO:0003924;GTPase activity;1.34381078592905e-11!GO:0010467;gene expression;1.36576173197195e-11!GO:0022618;protein-RNA complex assembly;1.98892667388569e-11!GO:0048193;Golgi vesicle transport;6.4952540528694e-11!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;8.13214599052709e-11!GO:0006512;ubiquitin cycle;1.44640813547785e-10!GO:0051603;proteolysis involved in cellular protein catabolic process;1.80560609031886e-10!GO:0005654;nucleoplasm;1.81672685357718e-10!GO:0006605;protein targeting;2.72859086633661e-10!GO:0006511;ubiquitin-dependent protein catabolic process;2.7885735687607e-10!GO:0016044;membrane organization and biogenesis;2.87019952209203e-10!GO:0019941;modification-dependent protein catabolic process;3.04378029792788e-10!GO:0043632;modification-dependent macromolecule catabolic process;3.04378029792788e-10!GO:0044257;cellular protein catabolic process;3.62062535048548e-10!GO:0051082;unfolded protein binding;5.59299553494439e-10!GO:0007264;small GTPase mediated signal transduction;5.994961603915e-10!GO:0008135;translation factor activity, nucleic acid binding;6.44678711447219e-10!GO:0008134;transcription factor binding;7.00328440494255e-10!GO:0015935;small ribosomal subunit;8.81901518244237e-10!GO:0045045;secretory pathway;1.07952455546623e-09!GO:0008092;cytoskeletal protein binding;1.10898263109469e-09!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;1.16212022494835e-09!GO:0044451;nucleoplasm part;1.34159217560923e-09!GO:0044265;cellular macromolecule catabolic process;1.41982711431109e-09!GO:0008565;protein transporter activity;1.68946253903777e-09!GO:0005768;endosome;1.86005554173455e-09!GO:0000502;proteasome complex (sensu Eukaryota);1.9220970333044e-09!GO:0005525;GTP binding;2.14767124898535e-09!GO:0007010;cytoskeleton organization and biogenesis;2.79333470984396e-09!GO:0019829;cation-transporting ATPase activity;3.21204755022814e-09!GO:0043412;biopolymer modification;5.02981257070139e-09!GO:0051186;cofactor metabolic process;8.14839405773702e-09!GO:0030695;GTPase regulator activity;8.42485656717869e-09!GO:0043687;post-translational protein modification;9.64456715712675e-09!GO:0006464;protein modification process;1.03802160157248e-08!GO:0006810;transport;1.49132546365407e-08!GO:0015934;large ribosomal subunit;1.50350343236587e-08!GO:0044248;cellular catabolic process;2.3311795496886e-08!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.47130052470707e-08!GO:0005783;endoplasmic reticulum;2.68072655230642e-08!GO:0015630;microtubule cytoskeleton;2.70571562528296e-08!GO:0051179;localization;3.49519770387388e-08!GO:0006793;phosphorus metabolic process;4.2775865597784e-08!GO:0006796;phosphate metabolic process;4.2775865597784e-08!GO:0032561;guanyl ribonucleotide binding;4.61659785372667e-08!GO:0019001;guanyl nucleotide binding;4.61659785372667e-08!GO:0048523;negative regulation of cellular process;5.45363548755258e-08!GO:0030135;coated vesicle;6.00753941108671e-08!GO:0043285;biopolymer catabolic process;6.58141521218016e-08!GO:0015986;ATP synthesis coupled proton transport;1.00720832639316e-07!GO:0015985;energy coupled proton transport, down electrochemical gradient;1.00720832639316e-07!GO:0030163;protein catabolic process;1.11227745227392e-07!GO:0016604;nuclear body;1.27612882390016e-07!GO:0006446;regulation of translational initiation;1.27612882390016e-07!GO:0006413;translational initiation;1.34980494513748e-07!GO:0005083;small GTPase regulator activity;1.67594967802267e-07!GO:0000398;nuclear mRNA splicing, via spliceosome;1.69475821907796e-07!GO:0000375;RNA splicing, via transesterification reactions;1.69475821907796e-07!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.69475821907796e-07!GO:0006913;nucleocytoplasmic transport;1.9480369149888e-07!GO:0003743;translation initiation factor activity;2.60407322111288e-07!GO:0006461;protein complex assembly;2.65938778884318e-07!GO:0016607;nuclear speck;2.77263474923494e-07!GO:0005761;mitochondrial ribosome;3.3188481655318e-07!GO:0000313;organellar ribosome;3.3188481655318e-07!GO:0044431;Golgi apparatus part;3.3188481655318e-07!GO:0051169;nuclear transport;3.51862267500916e-07!GO:0030036;actin cytoskeleton organization and biogenesis;4.10776146254682e-07!GO:0006897;endocytosis;4.10776146254682e-07!GO:0010324;membrane invagination;4.10776146254682e-07!GO:0009060;aerobic respiration;4.88433273702648e-07!GO:0005635;nuclear envelope;7.31809207835568e-07!GO:0051234;establishment of localization;7.48804955986702e-07!GO:0015631;tubulin binding;7.77574487705775e-07!GO:0031965;nuclear membrane;8.17144703817758e-07!GO:0009057;macromolecule catabolic process;8.23841144336623e-07!GO:0032559;adenyl ribonucleotide binding;8.40494640110856e-07!GO:0032940;secretion by cell;8.40494640110856e-07!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);9.07834376377581e-07!GO:0048471;perinuclear region of cytoplasm;9.70222847906779e-07!GO:0005874;microtubule;1.18265421294577e-06!GO:0045333;cellular respiration;1.35964468301643e-06!GO:0008639;small protein conjugating enzyme activity;1.65709807810562e-06!GO:0048519;negative regulation of biological process;1.6712053448726e-06!GO:0006732;coenzyme metabolic process;1.73089582906371e-06!GO:0046034;ATP metabolic process;2.27370210016943e-06!GO:0048475;coated membrane;2.34838271901085e-06!GO:0030117;membrane coat;2.34838271901085e-06!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;2.3799299688117e-06!GO:0004842;ubiquitin-protein ligase activity;2.3799299688117e-06!GO:0019787;small conjugating protein ligase activity;2.38729840485002e-06!GO:0005524;ATP binding;2.41034960694248e-06!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.42571666205542e-06!GO:0031252;leading edge;2.98985539590142e-06!GO:0006754;ATP biosynthetic process;3.47597270847279e-06!GO:0006753;nucleoside phosphate metabolic process;3.47597270847279e-06!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.59633516775808e-06!GO:0030554;adenyl nucleotide binding;3.6391534763475e-06!GO:0017038;protein import;3.81136636560399e-06!GO:0005905;coated pit;4.01291535685876e-06!GO:0030029;actin filament-based process;4.43483169156344e-06!GO:0016469;proton-transporting two-sector ATPase complex;4.44661620725358e-06!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.44661620725358e-06!GO:0009144;purine nucleoside triphosphate metabolic process;4.44661620725358e-06!GO:0009141;nucleoside triphosphate metabolic process;4.68353701155111e-06!GO:0009055;electron carrier activity;4.94302700222346e-06!GO:0009199;ribonucleoside triphosphate metabolic process;5.65346621369291e-06!GO:0009150;purine ribonucleotide metabolic process;5.74519383964467e-06!GO:0016310;phosphorylation;5.85133254872331e-06!GO:0006163;purine nucleotide metabolic process;5.9766273606839e-06!GO:0005730;nucleolus;6.2934669693504e-06!GO:0006099;tricarboxylic acid cycle;7.27612924160679e-06!GO:0046356;acetyl-CoA catabolic process;7.27612924160679e-06!GO:0009152;purine ribonucleotide biosynthetic process;7.9608016489202e-06!GO:0006164;purine nucleotide biosynthetic process;8.82528098203003e-06!GO:0008287;protein serine/threonine phosphatase complex;9.225470024687e-06!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;9.64658855587974e-06!GO:0009145;purine nucleoside triphosphate biosynthetic process;9.64658855587974e-06!GO:0019899;enzyme binding;1.01084366944055e-05!GO:0009109;coenzyme catabolic process;1.18250567424847e-05!GO:0043005;neuron projection;1.19303780135429e-05!GO:0000902;cell morphogenesis;1.19506043449552e-05!GO:0032989;cellular structure morphogenesis;1.19506043449552e-05!GO:0015078;hydrogen ion transmembrane transporter activity;1.23356166532294e-05!GO:0009142;nucleoside triphosphate biosynthetic process;1.23356166532294e-05!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.23356166532294e-05!GO:0051246;regulation of protein metabolic process;1.30466239647932e-05!GO:0045259;proton-transporting ATP synthase complex;1.30466239647932e-05!GO:0016881;acid-amino acid ligase activity;1.3259217750066e-05!GO:0009259;ribonucleotide metabolic process;1.33756131682124e-05!GO:0044440;endosomal part;1.42632979406708e-05!GO:0010008;endosome membrane;1.42632979406708e-05!GO:0000139;Golgi membrane;1.57585124638504e-05!GO:0016887;ATPase activity;1.67932184254646e-05!GO:0005769;early endosome;1.6908104289937e-05!GO:0016879;ligase activity, forming carbon-nitrogen bonds;1.88644174582987e-05!GO:0007399;nervous system development;2.40551165469078e-05!GO:0012501;programmed cell death;2.60051330472001e-05!GO:0051187;cofactor catabolic process;2.62919808587024e-05!GO:0008017;microtubule binding;3.04576791197486e-05!GO:0030136;clathrin-coated vesicle;3.16883194249526e-05!GO:0015077;monovalent inorganic cation transmembrane transporter activity;3.30101089360652e-05!GO:0003712;transcription cofactor activity;3.38102084102703e-05!GO:0008219;cell death;3.44344747806817e-05!GO:0016265;death;3.44344747806817e-05!GO:0006915;apoptosis;3.44927783210229e-05!GO:0006084;acetyl-CoA metabolic process;3.58190143529601e-05!GO:0042623;ATPase activity, coupled;3.84619748215431e-05!GO:0003779;actin binding;3.9685878358828e-05!GO:0007242;intracellular signaling cascade;3.9685878358828e-05!GO:0009260;ribonucleotide biosynthetic process;4.23173645062598e-05!GO:0044432;endoplasmic reticulum part;4.38862691170541e-05!GO:0005770;late endosome;4.99849809276508e-05!GO:0016564;transcription repressor activity;5.0296848228257e-05!GO:0008047;enzyme activator activity;5.25017582967709e-05!GO:0005096;GTPase activator activity;7.49424257947037e-05!GO:0045786;negative regulation of progression through cell cycle;8.94394739663991e-05!GO:0000245;spliceosome assembly;9.78881742885961e-05!GO:0030120;vesicle coat;9.97881764697512e-05!GO:0030662;coated vesicle membrane;9.97881764697512e-05!GO:0044453;nuclear membrane part;0.000101165456205788!GO:0007265;Ras protein signal transduction;0.000104875636048081!GO:0006606;protein import into nucleus;0.000128537778100035!GO:0009056;catabolic process;0.000130032920440151!GO:0019717;synaptosome;0.000141767283027374!GO:0051170;nuclear import;0.000144194523000329!GO:0005643;nuclear pore;0.000174774688495941!GO:0051188;cofactor biosynthetic process;0.000186873816534813!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000192602832367687!GO:0015399;primary active transmembrane transporter activity;0.000192602832367687!GO:0051128;regulation of cellular component organization and biogenesis;0.00021059872137924!GO:0043069;negative regulation of programmed cell death;0.000232669809292752!GO:0000159;protein phosphatase type 2A complex;0.000242909049806469!GO:0031072;heat shock protein binding;0.000293352893617499!GO:0003714;transcription corepressor activity;0.000317225983673195!GO:0043066;negative regulation of apoptosis;0.000327305755775298!GO:0032446;protein modification by small protein conjugation;0.000333547909447265!GO:0005875;microtubule associated complex;0.00035334326628231!GO:0042175;nuclear envelope-endoplasmic reticulum network;0.000359421434378358!GO:0003729;mRNA binding;0.000360045110556998!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000360060884593337!GO:0006366;transcription from RNA polymerase II promoter;0.000373319879338689!GO:0006752;group transfer coenzyme metabolic process;0.000373319879338689!GO:0006403;RNA localization;0.000381955443662582!GO:0030118;clathrin coat;0.000385602406610187!GO:0016070;RNA metabolic process;0.000385602406610187!GO:0005789;endoplasmic reticulum membrane;0.000389814564913523!GO:0016197;endosome transport;0.000394520092655655!GO:0005741;mitochondrial outer membrane;0.000437633015976739!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000449568560324149!GO:0004812;aminoacyl-tRNA ligase activity;0.000449568560324149!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000449568560324149!GO:0048468;cell development;0.000454233613819624!GO:0006607;NLS-bearing substrate import into nucleus;0.000457974435361329!GO:0015980;energy derivation by oxidation of organic compounds;0.00046021022736722!GO:0043492;ATPase activity, coupled to movement of substances;0.000461306424102146!GO:0050657;nucleic acid transport;0.000461306424102146!GO:0051236;establishment of RNA localization;0.000461306424102146!GO:0050658;RNA transport;0.000461306424102146!GO:0006325;establishment and/or maintenance of chromatin architecture;0.000472443696711488!GO:0031901;early endosome membrane;0.000473447600835625!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000474520483199246!GO:0005798;Golgi-associated vesicle;0.000477871208771546!GO:0016126;sterol biosynthetic process;0.000491805978592105!GO:0006613;cotranslational protein targeting to membrane;0.00050468904902636!GO:0030133;transport vesicle;0.000517714298490587!GO:0016567;protein ubiquitination;0.000541907278413759!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000543594039756408!GO:0006888;ER to Golgi vesicle-mediated transport;0.000555158245901658!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.000602335391420959!GO:0043038;amino acid activation;0.000631556248098675!GO:0006418;tRNA aminoacylation for protein translation;0.000631556248098675!GO:0043039;tRNA aminoacylation;0.000631556248098675!GO:0022890;inorganic cation transmembrane transporter activity;0.000640776438765706!GO:0006916;anti-apoptosis;0.000677562496839046!GO:0005793;ER-Golgi intermediate compartment;0.00069105167490617!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000787364904422401!GO:0030532;small nuclear ribonucleoprotein complex;0.000857244353502275!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000926588504020797!GO:0050789;regulation of biological process;0.000942823991424287!GO:0008601;protein phosphatase type 2A regulator activity;0.000942823991424287!GO:0005773;vacuole;0.000957800521144589!GO:0030027;lamellipodium;0.000960729795005666!GO:0051087;chaperone binding;0.00101978419318024!GO:0008361;regulation of cell size;0.00113529257093118!GO:0000151;ubiquitin ligase complex;0.0012290038707964!GO:0008654;phospholipid biosynthetic process;0.00126548262102585!GO:0006892;post-Golgi vesicle-mediated transport;0.0012919618197387!GO:0006323;DNA packaging;0.00130080014186558!GO:0031968;organelle outer membrane;0.00137408854352647!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00137408854352647!GO:0019867;outer membrane;0.00141718432998972!GO:0016791;phosphoric monoester hydrolase activity;0.00143347211987732!GO:0030867;rough endoplasmic reticulum membrane;0.00144240941742814!GO:0043566;structure-specific DNA binding;0.00152063107267977!GO:0004721;phosphoprotein phosphatase activity;0.00158955610981065!GO:0050794;regulation of cellular process;0.00160303367709528!GO:0005791;rough endoplasmic reticulum;0.00174948207819969!GO:0016050;vesicle organization and biogenesis;0.00181096762968038!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00184934526525257!GO:0016049;cell growth;0.00187905522479357!GO:0009108;coenzyme biosynthetic process;0.00191951785936946!GO:0051056;regulation of small GTPase mediated signal transduction;0.00191951785936946!GO:0005938;cell cortex;0.00194342792214396!GO:0006414;translational elongation;0.00195055424673621!GO:0050767;regulation of neurogenesis;0.00195055424673621!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.00199944202455783!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.00199944202455783!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.00199944202455783!GO:0003724;RNA helicase activity;0.00205823128064756!GO:0019208;phosphatase regulator activity;0.00216043604362355!GO:0016568;chromatin modification;0.00218369986185366!GO:0009117;nucleotide metabolic process;0.00222190434386213!GO:0009966;regulation of signal transduction;0.00224400284352792!GO:0046467;membrane lipid biosynthetic process;0.00225810793884888!GO:0007019;microtubule depolymerization;0.00229454017663585!GO:0009892;negative regulation of metabolic process;0.00230727174961533!GO:0006259;DNA metabolic process;0.00242737160040875!GO:0016311;dephosphorylation;0.00264632928153755!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.00270112341545071!GO:0008026;ATP-dependent helicase activity;0.00284014986619377!GO:0030425;dendrite;0.00287437115209556!GO:0007017;microtubule-based process;0.0030009744112294!GO:0022406;membrane docking;0.00308277802209812!GO:0048278;vesicle docking;0.00308277802209812!GO:0005839;proteasome core complex (sensu Eukaryota);0.00310742451309235!GO:0006650;glycerophospholipid metabolic process;0.00312864123489878!GO:0043623;cellular protein complex assembly;0.00315109876986727!GO:0001726;ruffle;0.00319359269117408!GO:0008139;nuclear localization sequence binding;0.00323997974294941!GO:0031111;negative regulation of microtubule polymerization or depolymerization;0.00361553655866649!GO:0006402;mRNA catabolic process;0.00389217472546279!GO:0003697;single-stranded DNA binding;0.00407103168778415!GO:0043209;myelin sheath;0.00411738381395022!GO:0030132;clathrin coat of coated pit;0.00416418757860339!GO:0051028;mRNA transport;0.00416418757860339!GO:0001508;regulation of action potential;0.00424636742152961!GO:0051726;regulation of cell cycle;0.00435992140056782!GO:0005813;centrosome;0.00450924374973314!GO:0000323;lytic vacuole;0.00457570023287379!GO:0005764;lysosome;0.00457570023287379!GO:0007243;protein kinase cascade;0.00460654883708307!GO:0001505;regulation of neurotransmitter levels;0.00460654883708307!GO:0004386;helicase activity;0.00472805011690912!GO:0007272;ensheathment of neurons;0.00476814892758361!GO:0008366;axon ensheathment;0.00476814892758361!GO:0050811;GABA receptor binding;0.00495726627476983!GO:0044448;cell cortex part;0.00496680064568792!GO:0048487;beta-tubulin binding;0.00496680064568792!GO:0006904;vesicle docking during exocytosis;0.0050824261288065!GO:0005085;guanyl-nucleotide exchange factor activity;0.00509984122534015!GO:0030865;cortical cytoskeleton organization and biogenesis;0.00513361925232613!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0051816645271035!GO:0051129;negative regulation of cellular component organization and biogenesis;0.00545000188102468!GO:0030426;growth cone;0.0055626871858441!GO:0019904;protein domain specific binding;0.00564810548213089!GO:0005100;Rho GTPase activator activity;0.00583391781050893!GO:0004722;protein serine/threonine phosphatase activity;0.0059635750423743!GO:0003676;nucleic acid binding;0.00650940483551209!GO:0000074;regulation of progression through cell cycle;0.00669741966142836!GO:0031114;regulation of microtubule depolymerization;0.00674571139752201!GO:0007026;negative regulation of microtubule depolymerization;0.00674571139752201!GO:0030424;axon;0.00679992916946564!GO:0030427;site of polarized growth;0.00686120727575483!GO:0006470;protein amino acid dephosphorylation;0.00686198480037541!GO:0016481;negative regulation of transcription;0.0069255739202685!GO:0008286;insulin receptor signaling pathway;0.00695767063013138!GO:0031324;negative regulation of cellular metabolic process;0.00696993316601636!GO:0051920;peroxiredoxin activity;0.00697599379591471!GO:0019888;protein phosphatase regulator activity;0.00702005050388432!GO:0043284;biopolymer biosynthetic process;0.00720904920000044!GO:0016301;kinase activity;0.00726254323827219!GO:0012506;vesicle membrane;0.00739017607632091!GO:0045187;regulation of circadian sleep/wake cycle, sleep;0.00739017607632091!GO:0004667;prostaglandin-D synthase activity;0.00739017607632091!GO:0050802;circadian sleep/wake cycle, sleep;0.00739017607632091!GO:0022410;circadian sleep/wake cycle process;0.00739017607632091!GO:0042749;regulation of circadian sleep/wake cycle;0.00739017607632091!GO:0008154;actin polymerization and/or depolymerization;0.007401078966598!GO:0005762;mitochondrial large ribosomal subunit;0.00741342370726495!GO:0000315;organellar large ribosomal subunit;0.00741342370726495!GO:0051540;metal cluster binding;0.00744666620260304!GO:0051536;iron-sulfur cluster binding;0.00744666620260304!GO:0008610;lipid biosynthetic process;0.00767975087579276!GO:0006695;cholesterol biosynthetic process;0.00769113600253015!GO:0043021;ribonucleoprotein binding;0.00771702341655647!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00787545011848405!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00845023506908191!GO:0006643;membrane lipid metabolic process;0.0084729041552478!GO:0007266;Rho protein signal transduction;0.00867057486568727!GO:0005869;dynactin complex;0.00884534509880629!GO:0007049;cell cycle;0.00898548159107328!GO:0051789;response to protein stimulus;0.00951232750462034!GO:0006986;response to unfolded protein;0.00951232750462034!GO:0048500;signal recognition particle;0.00968371906043348!GO:0006612;protein targeting to membrane;0.00995905319127178!GO:0000314;organellar small ribosomal subunit;0.0100930841687555!GO:0005763;mitochondrial small ribosomal subunit;0.0100930841687555!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.010289109265412!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.01045133038272!GO:0004674;protein serine/threonine kinase activity;0.0104863784728005!GO:0046578;regulation of Ras protein signal transduction;0.0105050690297098!GO:0046930;pore complex;0.0105757383123419!GO:0005815;microtubule organizing center;0.0107164329871294!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.0107298860522204!GO:0019887;protein kinase regulator activity;0.0108994426830688!GO:0046870;cadmium ion binding;0.0110076521028157!GO:0005099;Ras GTPase activator activity;0.0110815312715587!GO:0030742;GTP-dependent protein binding;0.0110815312715587!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.0110815312715587!GO:0005048;signal sequence binding;0.0111466145763835!GO:0048489;synaptic vesicle transport;0.0112022561267496!GO:0005868;cytoplasmic dynein complex;0.0112757914665067!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.0113885033348701!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.0113885033348701!GO:0060052;neurofilament cytoskeleton organization and biogenesis;0.0114822881573081!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;0.0116080953372526!GO:0065002;intracellular protein transport across a membrane;0.011678692471384!GO:0030320;cellular monovalent inorganic anion homeostasis;0.011678692471384!GO:0055083;monovalent inorganic anion homeostasis;0.011678692471384!GO:0055064;chloride ion homeostasis;0.011678692471384!GO:0030644;cellular chloride ion homeostasis;0.011678692471384!GO:0008021;synaptic vesicle;0.011678692471384!GO:0004298;threonine endopeptidase activity;0.0120222756662312!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0123057294488455!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.0129147691399669!GO:0031902;late endosome membrane;0.0129743005017775!GO:0003746;translation elongation factor activity;0.0131780521096431!GO:0006891;intra-Golgi vesicle-mediated transport;0.0132733288231975!GO:0001666;response to hypoxia;0.0136671831360348!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0141704303007759!GO:0033673;negative regulation of kinase activity;0.0146682042561961!GO:0006469;negative regulation of protein kinase activity;0.0146682042561961!GO:0031124;mRNA 3'-end processing;0.0146682042561961!GO:0006333;chromatin assembly or disassembly;0.0151448980570641!GO:0000059;protein import into nucleus, docking;0.0154941510532068!GO:0051168;nuclear export;0.015525061639729!GO:0019902;phosphatase binding;0.0158228299102056!GO:0001578;microtubule bundle formation;0.0159878523627447!GO:0051261;protein depolymerization;0.0161547933968058!GO:0050839;cell adhesion molecule binding;0.0162866586546728!GO:0042802;identical protein binding;0.0162866586546728!GO:0044433;cytoplasmic vesicle part;0.0163834838997872!GO:0005885;Arp2/3 protein complex;0.0165939222409075!GO:0008186;RNA-dependent ATPase activity;0.0166216035827698!GO:0007005;mitochondrion organization and biogenesis;0.0172488989368369!GO:0001558;regulation of cell growth;0.0176491396810798!GO:0030119;AP-type membrane coat adaptor complex;0.018101909253663!GO:0045892;negative regulation of transcription, DNA-dependent;0.018101909253663!GO:0051287;NAD binding;0.0188331603565513!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0190058059428622!GO:0006665;sphingolipid metabolic process;0.01902075489474!GO:0030041;actin filament polymerization;0.019146022173712!GO:0035035;histone acetyltransferase binding;0.0192074530408383!GO:0030658;transport vesicle membrane;0.0193095312258853!GO:0030258;lipid modification;0.0194299329648886!GO:0030131;clathrin adaptor complex;0.0195858695060968!GO:0003690;double-stranded DNA binding;0.0201942883912021!GO:0016859;cis-trans isomerase activity;0.0205282928449273!GO:0008090;retrograde axon cargo transport;0.0208878240987852!GO:0033596;TSC1-TSC2 complex;0.0208878240987852!GO:0033693;neurofilament bundle assembly;0.0208878240987852!GO:0051348;negative regulation of transferase activity;0.0211872728268201!GO:0009165;nucleotide biosynthetic process;0.021418966575966!GO:0006672;ceramide metabolic process;0.0219496388764269!GO:0046488;phosphatidylinositol metabolic process;0.0223854752042899!GO:0043681;protein import into mitochondrion;0.0225509729326281!GO:0016740;transferase activity;0.0242148208739395!GO:0042578;phosphoric ester hydrolase activity;0.0242186955278524!GO:0030030;cell projection organization and biogenesis;0.025904479278188!GO:0048858;cell projection morphogenesis;0.025904479278188!GO:0032990;cell part morphogenesis;0.025904479278188!GO:0007050;cell cycle arrest;0.0259197743948578!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0261732125312824!GO:0045047;protein targeting to ER;0.0261732125312824!GO:0051427;hormone receptor binding;0.0262306841849149!GO:0019894;kinesin binding;0.0268130343596746!GO:0030660;Golgi-associated vesicle membrane;0.0275370255501383!GO:0051539;4 iron, 4 sulfur cluster binding;0.0275437876030113!GO:0043067;regulation of programmed cell death;0.0276002048219276!GO:0042254;ribosome biogenesis and assembly;0.0283537130879735!GO:0030384;phosphoinositide metabolic process;0.0292388362868772!GO:0015629;actin cytoskeleton;0.0296958273227644!GO:0048154;S100 beta binding;0.0297724020574699!GO:0000287;magnesium ion binding;0.0297724020574699!GO:0031628;opioid receptor binding;0.0297724020574699!GO:0031852;mu-type opioid receptor binding;0.0297724020574699!GO:0016579;protein deubiquitination;0.0298673325698336!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0303062440743703!GO:0031371;ubiquitin conjugating enzyme complex;0.0313714692266424!GO:0019752;carboxylic acid metabolic process;0.0325215924142635!GO:0042981;regulation of apoptosis;0.033065100970107!GO:0046519;sphingoid metabolic process;0.033065100970107!GO:0043488;regulation of mRNA stability;0.0331392627266779!GO:0043487;regulation of RNA stability;0.0331392627266779!GO:0030137;COPI-coated vesicle;0.0331392627266779!GO:0030125;clathrin vesicle coat;0.0331392627266779!GO:0030665;clathrin coated vesicle membrane;0.0331392627266779!GO:0046474;glycerophospholipid biosynthetic process;0.0332041735575504!GO:0051252;regulation of RNA metabolic process;0.0332348316240546!GO:0030659;cytoplasmic vesicle membrane;0.0332348316240546!GO:0008022;protein C-terminus binding;0.0333831075088932!GO:0004860;protein kinase inhibitor activity;0.0333831075088932!GO:0006399;tRNA metabolic process;0.0338179454677209!GO:0019783;small conjugating protein-specific protease activity;0.0338179454677209!GO:0042026;protein refolding;0.0339878380868533!GO:0009066;aspartate family amino acid metabolic process;0.0340273737299184!GO:0065007;biological regulation;0.0342359012142393!GO:0019911;structural constituent of myelin sheath;0.0343414709632243!GO:0042552;myelination;0.0344317380569306!GO:0000062;acyl-CoA binding;0.034966253215153!GO:0019207;kinase regulator activity;0.0352223119901131!GO:0003713;transcription coactivator activity;0.0352223119901131!GO:0043086;negative regulation of catalytic activity;0.035443647831171!GO:0006091;generation of precursor metabolites and energy;0.0360529669475184!GO:0016272;prefoldin complex;0.0363241391723629!GO:0050435;beta-amyloid metabolic process;0.0372912554174641!GO:0009081;branched chain family amino acid metabolic process;0.0372952045201582!GO:0017166;vinculin binding;0.0378761918113066!GO:0004004;ATP-dependent RNA helicase activity;0.0378761918113066!GO:0003711;transcription elongation regulator activity;0.0380326969590654!GO:0046839;phospholipid dephosphorylation;0.0380714646133526!GO:0015682;ferric iron transport;0.0384029501133574!GO:0015091;ferric iron transmembrane transporter activity;0.0384029501133574!GO:0031643;positive regulation of myelination;0.0384029501133574!GO:0007006;mitochondrial membrane organization and biogenesis;0.038423027602224!GO:0030911;TPR domain binding;0.0384950275290709!GO:0032287;myelin maintenance in the peripheral nervous system;0.0390932452547933!GO:0032838;cell projection cytoplasm;0.0390932452547933!GO:0033081;regulation of T cell differentiation in the thymus;0.0390932452547933!GO:0043217;myelin maintenance;0.0390932452547933!GO:0060087;relaxation of vascular smooth muscle;0.0390932452547933!GO:0032839;dendrite cytoplasm;0.0390932452547933!GO:0016408;C-acyltransferase activity;0.03977977475424!GO:0006082;organic acid metabolic process;0.0402415876231741!GO:0004843;ubiquitin-specific protease activity;0.0402415876231741!GO:0035257;nuclear hormone receptor binding;0.0409916692074377!GO:0017091;AU-rich element binding;0.0412605199040064!GO:0050779;RNA destabilization;0.0412605199040064!GO:0000289;poly(A) tail shortening;0.0412605199040064!GO:0045296;cadherin binding;0.041371351147959!GO:0006383;transcription from RNA polymerase III promoter;0.0417441681995579!GO:0030139;endocytic vesicle;0.0417737497464726!GO:0031123;RNA 3'-end processing;0.0425544402399741!GO:0005856;cytoskeleton;0.0425544402399741!GO:0031109;microtubule polymerization or depolymerization;0.0426574814687134!GO:0000209;protein polyubiquitination;0.0430750928829104!GO:0051276;chromosome organization and biogenesis;0.04308338653599!GO:0016615;malate dehydrogenase activity;0.0441463800168019!GO:0042995;cell projection;0.0441463800168019!GO:0006611;protein export from nucleus;0.0447264170531711!GO:0007034;vacuolar transport;0.0454099620004963!GO:0065009;regulation of a molecular function;0.0470645592737416!GO:0008250;oligosaccharyl transferase complex;0.0470702762362818!GO:0004221;ubiquitin thiolesterase activity;0.0487079381892269!GO:0021782;glial cell development;0.0493279615002444!GO:0022008;neurogenesis;0.0495408041946109!GO:0005667;transcription factor complex;0.0496734083372674!GO:0008312;7S RNA binding;0.0496734083372674!GO:0008180;signalosome;0.0497947296323175!GO:0030641;cellular hydrogen ion homeostasis;0.0498777022389599 | |||
|sample_id=10182 | |sample_id=10182 | ||
|sample_note=biological replicate | |sample_note=biological replicate | ||
| Line 76: | Line 100: | ||
|sample_tissue=locus coeruleus | |sample_tissue=locus coeruleus | ||
|top_motifs=REST:3.4612153696;SOX2:3.26847257765;MYFfamily:3.25720988543;NHLH1,2:3.1926523195;MTF1:3.17597833668;SOX5:3.11723342931;RREB1:3.07495197278;ZFP161:2.97161365241;HIC1:2.82044729224;DBP:2.73683031051;MED-1{core}:2.63268911072;NFIX:2.61926454577;PRDM1:2.61461677855;PRRX1,2:2.55195947251;MTE{core}:2.54256120786;ATF2:2.49698064446;RFX1:2.48625688943;SOX{8,9,10}:2.47400080459;RFX2..5_RFXANK_RFXAP:2.41887829559;ZBTB6:2.409318411;TFAP2B:2.37338760627;CUX2:2.37268629176;NANOG:2.29772577751;LMO2:2.24834892161;GFI1B:2.22705347954;OCT4_SOX2{dimer}:2.22424281469;EGR1..3:2.202735277;GATA4:2.19212214499;NKX3-2:2.18006628059;GTF2I:2.17794203561;KLF4:2.16808997816;PAX6:2.15119172651;SMAD1..7,9:2.14486352473;HOXA9_MEIS1:2.13430002242;FOXP3:2.11279044092;TGIF1:2.05958290483;HOX{A6,A7,B6,B7}:2.05454003262;PATZ1:2.05242099696;SOX17:1.99883892868;JUN:1.99090069329;HBP1_HMGB_SSRP1_UBTF:1.92926540026;MZF1:1.91456556428;MAZ:1.76236469253;EP300:1.75830779643;BREu{core}:1.73542754936;FOXD3:1.69792833156;SP1:1.69294373999;ZNF384:1.63683783841;PAX5:1.63298467978;GCM1,2:1.61007581336;NKX6-1,2:1.60414865484;AHR_ARNT_ARNT2:1.5899397087;EBF1:1.56392946264;XBP1:1.54243101565;PDX1:1.51199414622;STAT2,4,6:1.50946317993;POU6F1:1.47505309352;FOXM1:1.47251600387;ZNF423:1.45915454318;TFDP1:1.41282739735;LEF1_TCF7_TCF7L1,2:1.3953982831;BPTF:1.35868645554;MYBL2:1.32370666205;FOXP1:1.28525526481;RBPJ:1.23371814522;POU5F1:1.23295099008;NR3C1:1.19865923251;STAT1,3:1.17381931286;NRF1:1.1734158979;RORA:1.16502925818;POU3F1..4:1.15345431815;IKZF2:1.1448834086;ZIC1..3:1.13654104034;TFAP2{A,C}:1.13142209846;CDC5L:1.10772719417;ARID5B:1.06533030224;TLX1..3_NFIC{dimer}:1.02253655765;VSX1,2:1.01491920051;FOXQ1:0.996437319196;NKX2-3_NKX2-5:0.970222462504;HOX{A4,D4}:0.909130809355;ONECUT1,2:0.847569930825;FOX{D1,D2}:0.83548915154;AR:0.764225752728;SREBF1,2:0.761159280039;CRX:0.73850932352;MAFB:0.707446416353;ZNF143:0.689192998852;LHX3,4:0.663356160293;ADNP_IRX_SIX_ZHX:0.64009222103;ZBTB16:0.628451345664;HMGA1,2:0.61175983417;PAX4:0.504485105883;CREB1:0.471432125052;GTF2A1,2:0.443717262151;FOXO1,3,4:0.440905925087;ESRRA:0.421624454881;T:0.420956320079;FOXN1:0.418598892451;NKX3-1:0.398190782075;ATF5_CREB3:0.317350056504;XCPE1{core}:0.310050967761;FOX{F1,F2,J1}:0.300845394414;IRF7:0.282013065057;FOX{I1,J2}:0.253852631567;ATF4:0.21054774742;GFI1:0.210192538507;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.155148317182;NFIL3:0.131394840093;EVI1:0.130683118449;PAX2:0.122302678184;HMX1:0.11609045008;GZF1:0.098230400282;MEF2{A,B,C,D}:0.0280197190496;PBX1:0.016836579756;NFY{A,B,C}:0.00548663563213;ALX1:-0.00715185644759;ZEB1:-0.0111020490585;HAND1,2:-0.0526798276773;NR5A1,2:-0.0748315978365;NFATC1..3:-0.0776234939237;IRF1,2:-0.0928309631718;SPZ1:-0.0944717758489;TFCP2:-0.0963175302361;NFE2L2:-0.098030067777;MYOD1:-0.119451471581;TOPORS:-0.120797505289;FOXL1:-0.178153747349;AIRE:-0.194314743359;ZNF238:-0.241518959283;NR1H4:-0.271014641218;NFE2L1:-0.275409052166;CEBPA,B_DDIT3:-0.277649403806;UFEwm:-0.282534065905;PAX3,7:-0.287809898827;CDX1,2,4:-0.307843555284;NFE2:-0.316750580281;ATF6:-0.329981772314;POU1F1:-0.339848685699;PITX1..3:-0.380874743071;NKX2-1,4:-0.390399578058;ALX4:-0.393494358076;GATA6:-0.469785895947;TBX4,5:-0.473235721751;YY1:-0.534181808042;FOXA2:-0.534259096111;SPI1:-0.577917426206;NANOG{mouse}:-0.581700490288;TP53:-0.591658027452;TBP:-0.596892931839;TLX2:-0.601202886153;TEF:-0.65698837616;ETS1,2:-0.659064052531;HNF4A_NR2F1,2:-0.666558495347;IKZF1:-0.68158762729;TFAP4:-0.702841512057;HNF1A:-0.73889951789;DMAP1_NCOR{1,2}_SMARC:-0.75438384131;NKX2-2,8:-0.77344025755;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.781022444692;SPIB:-0.806621209063;bHLH_family:-0.81142766039;HSF1,2:-0.88055871951;SNAI1..3:-0.905126291912;PAX8:-0.907077101738;HIF1A:-0.93185683147;TEAD1:-0.937193329778;ESR1:-0.940216968836;BACH2:-0.942597842913;FOS_FOS{B,L1}_JUN{B,D}:-0.948073139394;FOSL2:-0.990727282183;PAX1,9:-1.01080500855;SRF:-1.09195916311;E2F1..5:-1.2223350223;NFKB1_REL_RELA:-1.22604444369;HLF:-1.23533488092;ELK1,4_GABP{A,B1}:-1.24650392647;ELF1,2,4:-1.32985581098;RUNX1..3:-1.34702588647;RXR{A,B,G}:-1.3620364759;POU2F1..3:-1.36997617815;ZNF148:-1.43932916314;NR6A1:-1.52446640412;MYB:-1.53379996216;HES1:-1.59129664022;TAL1_TCF{3,4,12}:-1.71925284182;GLI1..3:-1.83532879427;PPARG:-1.96568154983;RXRA_VDR{dimer}:-2.33995500824;HOX{A5,B5}:-2.40760983777;STAT5{A,B}:-2.55389876892;EN1,2:-2.80531514899 | |top_motifs=REST:3.4612153696;SOX2:3.26847257765;MYFfamily:3.25720988543;NHLH1,2:3.1926523195;MTF1:3.17597833668;SOX5:3.11723342931;RREB1:3.07495197278;ZFP161:2.97161365241;HIC1:2.82044729224;DBP:2.73683031051;MED-1{core}:2.63268911072;NFIX:2.61926454577;PRDM1:2.61461677855;PRRX1,2:2.55195947251;MTE{core}:2.54256120786;ATF2:2.49698064446;RFX1:2.48625688943;SOX{8,9,10}:2.47400080459;RFX2..5_RFXANK_RFXAP:2.41887829559;ZBTB6:2.409318411;TFAP2B:2.37338760627;CUX2:2.37268629176;NANOG:2.29772577751;LMO2:2.24834892161;GFI1B:2.22705347954;OCT4_SOX2{dimer}:2.22424281469;EGR1..3:2.202735277;GATA4:2.19212214499;NKX3-2:2.18006628059;GTF2I:2.17794203561;KLF4:2.16808997816;PAX6:2.15119172651;SMAD1..7,9:2.14486352473;HOXA9_MEIS1:2.13430002242;FOXP3:2.11279044092;TGIF1:2.05958290483;HOX{A6,A7,B6,B7}:2.05454003262;PATZ1:2.05242099696;SOX17:1.99883892868;JUN:1.99090069329;HBP1_HMGB_SSRP1_UBTF:1.92926540026;MZF1:1.91456556428;MAZ:1.76236469253;EP300:1.75830779643;BREu{core}:1.73542754936;FOXD3:1.69792833156;SP1:1.69294373999;ZNF384:1.63683783841;PAX5:1.63298467978;GCM1,2:1.61007581336;NKX6-1,2:1.60414865484;AHR_ARNT_ARNT2:1.5899397087;EBF1:1.56392946264;XBP1:1.54243101565;PDX1:1.51199414622;STAT2,4,6:1.50946317993;POU6F1:1.47505309352;FOXM1:1.47251600387;ZNF423:1.45915454318;TFDP1:1.41282739735;LEF1_TCF7_TCF7L1,2:1.3953982831;BPTF:1.35868645554;MYBL2:1.32370666205;FOXP1:1.28525526481;RBPJ:1.23371814522;POU5F1:1.23295099008;NR3C1:1.19865923251;STAT1,3:1.17381931286;NRF1:1.1734158979;RORA:1.16502925818;POU3F1..4:1.15345431815;IKZF2:1.1448834086;ZIC1..3:1.13654104034;TFAP2{A,C}:1.13142209846;CDC5L:1.10772719417;ARID5B:1.06533030224;TLX1..3_NFIC{dimer}:1.02253655765;VSX1,2:1.01491920051;FOXQ1:0.996437319196;NKX2-3_NKX2-5:0.970222462504;HOX{A4,D4}:0.909130809355;ONECUT1,2:0.847569930825;FOX{D1,D2}:0.83548915154;AR:0.764225752728;SREBF1,2:0.761159280039;CRX:0.73850932352;MAFB:0.707446416353;ZNF143:0.689192998852;LHX3,4:0.663356160293;ADNP_IRX_SIX_ZHX:0.64009222103;ZBTB16:0.628451345664;HMGA1,2:0.61175983417;PAX4:0.504485105883;CREB1:0.471432125052;GTF2A1,2:0.443717262151;FOXO1,3,4:0.440905925087;ESRRA:0.421624454881;T:0.420956320079;FOXN1:0.418598892451;NKX3-1:0.398190782075;ATF5_CREB3:0.317350056504;XCPE1{core}:0.310050967761;FOX{F1,F2,J1}:0.300845394414;IRF7:0.282013065057;FOX{I1,J2}:0.253852631567;ATF4:0.21054774742;GFI1:0.210192538507;RXR{A,B,G}_{NR1H2,PPAR}dimers:0.155148317182;NFIL3:0.131394840093;EVI1:0.130683118449;PAX2:0.122302678184;HMX1:0.11609045008;GZF1:0.098230400282;MEF2{A,B,C,D}:0.0280197190496;PBX1:0.016836579756;NFY{A,B,C}:0.00548663563213;ALX1:-0.00715185644759;ZEB1:-0.0111020490585;HAND1,2:-0.0526798276773;NR5A1,2:-0.0748315978365;NFATC1..3:-0.0776234939237;IRF1,2:-0.0928309631718;SPZ1:-0.0944717758489;TFCP2:-0.0963175302361;NFE2L2:-0.098030067777;MYOD1:-0.119451471581;TOPORS:-0.120797505289;FOXL1:-0.178153747349;AIRE:-0.194314743359;ZNF238:-0.241518959283;NR1H4:-0.271014641218;NFE2L1:-0.275409052166;CEBPA,B_DDIT3:-0.277649403806;UFEwm:-0.282534065905;PAX3,7:-0.287809898827;CDX1,2,4:-0.307843555284;NFE2:-0.316750580281;ATF6:-0.329981772314;POU1F1:-0.339848685699;PITX1..3:-0.380874743071;NKX2-1,4:-0.390399578058;ALX4:-0.393494358076;GATA6:-0.469785895947;TBX4,5:-0.473235721751;YY1:-0.534181808042;FOXA2:-0.534259096111;SPI1:-0.577917426206;NANOG{mouse}:-0.581700490288;TP53:-0.591658027452;TBP:-0.596892931839;TLX2:-0.601202886153;TEF:-0.65698837616;ETS1,2:-0.659064052531;HNF4A_NR2F1,2:-0.666558495347;IKZF1:-0.68158762729;TFAP4:-0.702841512057;HNF1A:-0.73889951789;DMAP1_NCOR{1,2}_SMARC:-0.75438384131;NKX2-2,8:-0.77344025755;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.781022444692;SPIB:-0.806621209063;bHLH_family:-0.81142766039;HSF1,2:-0.88055871951;SNAI1..3:-0.905126291912;PAX8:-0.907077101738;HIF1A:-0.93185683147;TEAD1:-0.937193329778;ESR1:-0.940216968836;BACH2:-0.942597842913;FOS_FOS{B,L1}_JUN{B,D}:-0.948073139394;FOSL2:-0.990727282183;PAX1,9:-1.01080500855;SRF:-1.09195916311;E2F1..5:-1.2223350223;NFKB1_REL_RELA:-1.22604444369;HLF:-1.23533488092;ELK1,4_GABP{A,B1}:-1.24650392647;ELF1,2,4:-1.32985581098;RUNX1..3:-1.34702588647;RXR{A,B,G}:-1.3620364759;POU2F1..3:-1.36997617815;ZNF148:-1.43932916314;NR6A1:-1.52446640412;MYB:-1.53379996216;HES1:-1.59129664022;TAL1_TCF{3,4,12}:-1.71925284182;GLI1..3:-1.83532879427;PPARG:-1.96568154983;RXRA_VDR{dimer}:-2.33995500824;HOX{A5,B5}:-2.40760983777;STAT5{A,B}:-2.55389876892;EN1,2:-2.80531514899 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10182-103D2;search_select_hide=table117:FF:10182-103D2 | |||
}} | }} | ||
Latest revision as of 12:25, 3 June 2020
| Name: | locus coeruleus - adult, donor10196 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | CNhs13808 |
| Sample type: | tissues |
| Genomic View: | UCSC |
| RefEX: | Specific genes |
| FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9 |
| CAGEd-oPOSSUM: | link |
| ZENBU report : | link |
| Additional information | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sample information
RNA information
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| CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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| Download raw sequence, BAM & CTSS | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13808
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13808
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.0438 |
| 10 | 10 | 0.0425 |
| 100 | 100 | 0.333 |
| 101 | 101 | 0.824 |
| 102 | 102 | 0.876 |
| 103 | 103 | 0.0667 |
| 104 | 104 | 0.139 |
| 105 | 105 | 0.164 |
| 106 | 106 | 0.0521 |
| 107 | 107 | 0.167 |
| 108 | 108 | 0.913 |
| 109 | 109 | 0.00468 |
| 11 | 11 | 0.0105 |
| 110 | 110 | 0.0334 |
| 111 | 111 | 0.205 |
| 112 | 112 | 0.419 |
| 113 | 113 | 0.53 |
| 114 | 114 | 0.133 |
| 115 | 115 | 0.842 |
| 116 | 116 | 0.156 |
| 117 | 117 | 0.00714 |
| 118 | 118 | 0.0982 |
| 119 | 119 | 0.248 |
| 12 | 12 | 0.624 |
| 120 | 120 | 0.141 |
| 121 | 121 | 0.447 |
| 122 | 122 | 0.915 |
| 123 | 123 | 0.968 |
| 124 | 124 | 0.134 |
| 125 | 125 | 0.257 |
| 126 | 126 | 0.0686 |
| 127 | 127 | 0.45 |
| 128 | 128 | 0.225 |
| 129 | 129 | 0.448 |
| 13 | 13 | 0.00209 |
| 130 | 130 | 0.226 |
| 131 | 131 | 0.0231 |
| 132 | 132 | 0.732 |
| 133 | 133 | 0.0104 |
| 134 | 134 | 0.69 |
| 135 | 135 | 0.19 |
| 136 | 136 | 0.00643 |
| 137 | 137 | 0.574 |
| 138 | 138 | 0.775 |
| 139 | 139 | 0.108 |
| 14 | 14 | 0.898 |
| 140 | 140 | 0.55 |
| 141 | 141 | 0.496 |
| 142 | 142 | 0.827 |
| 143 | 143 | 0.0408 |
| 144 | 144 | 0.875 |
| 145 | 145 | 0.155 |
| 146 | 146 | 0.396 |
| 147 | 147 | 0.603 |
| 148 | 148 | 0.297 |
| 149 | 149 | 0.0955 |
| 15 | 15 | 0.0557 |
| 150 | 150 | 0.159 |
| 151 | 151 | 0.728 |
| 152 | 152 | 0.167 |
| 153 | 153 | 0.935 |
| 154 | 154 | 0.455 |
| 155 | 155 | 0.789 |
| 156 | 156 | 0.229 |
| 157 | 157 | 0.459 |
| 158 | 158 | 0.145 |
| 159 | 159 | 0.00649 |
| 16 | 16 | 0.0414 |
| 160 | 160 | 0.196 |
| 161 | 161 | 0.162 |
| 162 | 162 | 0.84 |
| 163 | 163 | 0.842 |
| 164 | 164 | 0.0108 |
| 165 | 165 | 0.114 |
| 166 | 166 | 0.963 |
| 167 | 167 | 0.783 |
| 168 | 168 | 0.357 |
| 169 | 169 | 0.0151 |
| 17 | 17 | 0.0898 |
| 18 | 18 | 0.072 |
| 19 | 19 | 0.285 |
| 2 | 2 | 0.895 |
| 20 | 20 | 0.171 |
| 21 | 21 | 0.0635 |
| 22 | 22 | 0.274 |
| 23 | 23 | 0.487 |
| 24 | 24 | 0.0379 |
| 25 | 25 | 0.53 |
| 26 | 26 | 1.51374e-4 |
| 27 | 27 | 0.722 |
| 28 | 28 | 0.791 |
| 29 | 29 | 0.00891 |
| 3 | 3 | 0.0371 |
| 30 | 30 | 0.866 |
| 31 | 31 | 0.901 |
| 32 | 32 | 0.0126 |
| 33 | 33 | 0.0704 |
| 34 | 34 | 0.739 |
| 35 | 35 | 0.378 |
| 36 | 36 | 0.173 |
| 37 | 37 | 0.0468 |
| 38 | 38 | 0.31 |
| 39 | 39 | 0.43 |
| 4 | 4 | 0.961 |
| 40 | 40 | 0.0577 |
| 41 | 41 | 0.29 |
| 42 | 42 | 0.209 |
| 43 | 43 | 0.118 |
| 44 | 44 | 0.122 |
| 45 | 45 | 0.714 |
| 46 | 46 | 0.0328 |
| 47 | 47 | 0.0488 |
| 48 | 48 | 0.0375 |
| 49 | 49 | 0.22 |
| 5 | 5 | 0.695 |
| 50 | 50 | 0.358 |
| 51 | 51 | 0.362 |
| 52 | 52 | 0.715 |
| 53 | 53 | 0.903 |
| 54 | 54 | 0.425 |
| 55 | 55 | 0.611 |
| 56 | 56 | 0.51 |
| 57 | 57 | 0.302 |
| 58 | 58 | 0.33 |
| 59 | 59 | 0.0664 |
| 6 | 6 | 0.939 |
| 60 | 60 | 0.114 |
| 61 | 61 | 0.0779 |
| 62 | 62 | 0.158 |
| 63 | 63 | 0.174 |
| 64 | 64 | 0.157 |
| 65 | 65 | 0.22 |
| 66 | 66 | 0.183 |
| 67 | 67 | 0.363 |
| 68 | 68 | 0.373 |
| 69 | 69 | 0.614 |
| 7 | 7 | 0.0847 |
| 70 | 70 | 0.0154 |
| 71 | 71 | 0.00566 |
| 72 | 72 | 0.356 |
| 73 | 73 | 0.0624 |
| 74 | 74 | 0.873 |
| 75 | 75 | 0.0204 |
| 76 | 76 | 0.303 |
| 77 | 77 | 0.162 |
| 78 | 78 | 0.00346 |
| 79 | 79 | 0.273 |
| 8 | 8 | 0.0575 |
| 80 | 80 | 0.458 |
| 81 | 81 | 0.427 |
| 82 | 82 | 0.621 |
| 83 | 83 | 0.0801 |
| 84 | 84 | 0.511 |
| 85 | 85 | 0.383 |
| 86 | 86 | 0.15 |
| 87 | 87 | 6.95285e-4 |
| 88 | 88 | 0.751 |
| 89 | 89 | 0.194 |
| 9 | 9 | 0.496 |
| 90 | 90 | 0.0842 |
| 91 | 91 | 0.699 |
| 92 | 92 | 0.562 |
| 93 | 93 | 0.585 |
| 94 | 94 | 0.129 |
| 95 | 95 | 0.0215 |
| 96 | 96 | 0.802 |
| 97 | 97 | 0.605 |
| 98 | 98 | 0.248 |
| 99 | 99 | 0.526 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13808
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
FF:0011487 human locus coeruleus- adult sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
UBERON: Anatomy
0000468 (multi-cellular organism)
0007023 (adult organism)
0000955 (brain)
0000988 (pons)
0002148 (locus ceruleus)
0000479 (tissue)
0004121 (ectoderm-derived structure)
0000064 (organ part)
0010314 (structure with developmental contribution from neural crest)
0011216 (organ system subdivision)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000063 (organ segment)
0000481 (multi-tissue structure)
0000073 (regional part of nervous system)
0000477 (anatomical cluster)
0003528 (brain grey matter)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0002680 (regional part of metencephalon)
0002616 (regional part of brain)
0004733 (segmental subdivision of hindbrain)
0004732 (segmental subdivision of nervous system)
0006331 (brainstem nucleus)
0009662 (hindbrain nucleus)
0000125 (neural nucleus)
0002020 (gray matter)
0010317 (germ layer / neural crest derived structure)
0002308 (nucleus of brain)
0001017 (central nervous system)
0001016 (nervous system)
0001895 (metencephalon)
0002298 (brainstem)
0002028 (hindbrain)
FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000998 (adult tissue sample)
0000004 (tissue sample)
0011487 (human locus coeruleus- adult sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0002532 (epiblast (generic))
UBERON:0006601 (presumptive ectoderm)
UBERON:0010316 (germ layer / neural crest)
