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Coexpression cluster:C135

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Full id: C135_neuroblastoma_retinoblastoma_carcinoid_choriocarcinoma_testicular_acute_rectum



Phase1 CAGE Peaks

Hg19::chr10:135139802..135139811,-p9@CALY
Hg19::chr11:71952706..71952712,-p4@PHOX2A
Hg19::chr11:71952721..71952728,-p6@PHOX2A
Hg19::chr11:71952772..71952788,-p@chr11:71952772..71952788
-
Hg19::chr11:71955210..71955227,-p1@PHOX2A
Hg19::chr11:72070206..72070217,-p@chr11:72070206..72070217
-
Hg19::chr11:8285219..8285232,-p8@LMO1
Hg19::chr14:36003132..36003155,-p@chr14:36003132..36003155
-
Hg19::chr14:36003180..36003191,-p@chr14:36003180..36003191
-
Hg19::chr14:36003234..36003238,-p@chr14:36003234..36003238
-
Hg19::chr14:36003363..36003378,+p1@INSM2
Hg19::chr14:36003405..36003408,+p3@INSM2
Hg19::chr14:89307203..89307210,+p5@TTC8
Hg19::chr14:89307222..89307227,+p7@TTC8
Hg19::chr14:89307231..89307234,+p8@TTC8
Hg19::chr14:89307240..89307249,+p4@TTC8
Hg19::chr14:89319304..89319352,+p@chr14:89319304..89319352
+
Hg19::chr16:55689872..55689912,+p1@SLC6A2
Hg19::chr17:61509320..61509322,-p@chr17:61509320..61509322
-
Hg19::chr19:30719524..30719534,+p@chr19:30719524..30719534
+
Hg19::chr1:109255524..109255546,+p1@FNDC7
Hg19::chr1:99470368..99470446,-p1@LPPR5
Hg19::chr20:21086993..21087007,-p1@LINC00237
Hg19::chr22:45405796..45405814,-p3@PHF21B
Hg19::chr2:137522983..137523027,+p4@THSD7B
Hg19::chr2:16080165..16080175,+p15@MYCN
Hg19::chr2:16080325..16080331,+p17@MYCN
Hg19::chr2:16080357..16080363,+p18@MYCN
Hg19::chr2:16080460..16080495,-p@chr2:16080460..16080495
-
Hg19::chr2:16080635..16080650,+p4@MYCN
Hg19::chr2:16080659..16080685,+p1@MYCN
Hg19::chr2:16080823..16080836,+p5@MYCN
Hg19::chr2:16081024..16081034,+p10@MYCN
Hg19::chr2:16081392..16081406,-p3@MYCNOS
Hg19::chr2:16081716..16081740,-p2@MYCNOS
Hg19::chr2:16081744..16081768,-p5@MYCNOS
Hg19::chr2:16081783..16081817,-p1@MYCNOS
Hg19::chr2:16081912..16081931,+p2@MYCN
Hg19::chr2:16082094..16082106,+p7@MYCN
Hg19::chr2:16082155..16082169,+p3@MYCN
Hg19::chr2:16082384..16082391,+p9@MYCN
Hg19::chr2:16082395..16082415,+p6@MYCN
Hg19::chr2:16082418..16082429,+p8@MYCN
Hg19::chr2:16082486..16082491,+p13@MYCN
Hg19::chr2:16082851..16082860,+p@chr2:16082851..16082860
+
Hg19::chr2:16082878..16082890,+p@chr2:16082878..16082890
+
Hg19::chr2:16082902..16082908,+p@chr2:16082902..16082908
+
Hg19::chr2:16082933..16082942,+p@chr2:16082933..16082942
+
Hg19::chr2:16083539..16083543,+p@chr2:16083539..16083543
+
Hg19::chr2:16085596..16085604,+p@chr2:16085596..16085604
+
Hg19::chr2:16085699..16085709,+p@chr2:16085699..16085709
+
Hg19::chr2:16085756..16085766,+p@chr2:16085756..16085766
+
Hg19::chr2:16085836..16085841,-p@chr2:16085836..16085841
-
Hg19::chr2:16085862..16085895,-p@chr2:16085862..16085895
-
Hg19::chr2:16085916..16085937,-p@chr2:16085916..16085937
-
Hg19::chr2:16122765..16122769,-p@chr2:16122765..16122769
-
Hg19::chr2:16361177..16361195,-p@chr2:16361177..16361195
-
Hg19::chr2:16383015..16383029,-p@chr2:16383015..16383029
-
Hg19::chr2:16405283..16405330,+p1@ENST00000420404
Hg19::chr2:16504184..16504211,+p@chr2:16504184..16504211
+
Hg19::chr2:173724826..173724840,+p15@RAPGEF4
Hg19::chr2:173724864..173724875,+p11@RAPGEF4
Hg19::chr2:173724876..173724893,+p16@RAPGEF4
Hg19::chr2:192364133..192364143,+p@chr2:192364133..192364143
+
Hg19::chr2:30099704..30099722,-p@chr2:30099704..30099722
-
Hg19::chr2:30099741..30099749,-p@chr2:30099741..30099749
-
Hg19::chr2:74726898..74726903,+p@chr2:74726898..74726903
+
Hg19::chr2:74735271..74735288,-p10@PCGF1
Hg19::chr2:74735290..74735299,-p11@PCGF1
Hg19::chr2:74735317..74735338,-p5@PCGF1
Hg19::chr2:74740569..74740580,+p4@TLX2
Hg19::chr2:74741569..74741620,+p1@TLX2
Hg19::chr2:74743961..74743965,+p@chr2:74743961..74743965
+
Hg19::chr4:113869733..113869760,+p@chr4:113869733..113869760
+
Hg19::chr4:113870230..113870237,+p@chr4:113870230..113870237
+
Hg19::chr4:151509442..151509449,-p@chr4:151509442..151509449
-
Hg19::chr4:151509505..151509510,-p@chr4:151509505..151509510
-
Hg19::chr4:151509549..151509560,-p@chr4:151509549..151509560
-
Hg19::chr4:151509603..151509613,-p@chr4:151509603..151509613
-
Hg19::chr4:151509614..151509615,-p@chr4:151509614..151509615
-
Hg19::chr4:151509622..151509629,-p@chr4:151509622..151509629
-
Hg19::chr4:174427862..174427899,+p@chr4:174427862..174427899
+
Hg19::chr4:174429225..174429237,+p@chr4:174429225..174429237
+
Hg19::chr4:174429255..174429289,+p@chr4:174429255..174429289
+
Hg19::chr4:174429652..174429665,+p@chr4:174429652..174429665
+
Hg19::chr4:174440390..174440400,-p@chr4:174440390..174440400
-
Hg19::chr4:174440405..174440414,-p@chr4:174440405..174440414
-
Hg19::chr4:174930472..174930480,-p@chr4:174930472..174930480
-
Hg19::chr4:174930493..174930503,-p@chr4:174930493..174930503
-
Hg19::chr4:174930547..174930558,-p@chr4:174930547..174930558
-
Hg19::chr4:175028534..175028537,-p@chr4:175028534..175028537
-
Hg19::chr4:175041663..175041727,-p1@ENST00000503140
Hg19::chr4:21699314..21699327,-p7@KCNIP4
Hg19::chr4:21699348..21699355,-p25@KCNIP4
Hg19::chr4:21699357..21699368,-p18@KCNIP4
Hg19::chr4:21699380..21699386,-p20@KCNIP4
Hg19::chr4:41859832..41859854,+p@chr4:41859832..41859854
+
Hg19::chr4:41875797..41875802,-p@chr4:41875797..41875802
-
Hg19::chr4:41884582..41884593,-p1@ENST00000499082
Hg19::chr4:41884620..41884663,-p1@ENST00000504870
Hg19::chr4:48485220..48485230,+p10@SLC10A4
Hg19::chr4:48485239..48485249,+p9@SLC10A4
Hg19::chr4:48485341..48485394,+p1@SLC10A4
Hg19::chr4:48485400..48485411,+p3@SLC10A4
Hg19::chr4:48485413..48485423,+p5@SLC10A4
Hg19::chr4:48485436..48485441,+p12@SLC10A4
Hg19::chr4:48485486..48485499,+p2@SLC10A4
Hg19::chr4:95983128..95983134,+p@chr4:95983128..95983134
+
Hg19::chr5:168271822..168271868,-p5@SLIT3
Hg19::chr5:168271880..168271889,-p15@SLIT3
Hg19::chr5:50761081..50761087,-p@chr5:50761081..50761087
-
Hg19::chr5:51202170..51202198,+p@chr5:51202170..51202198
+
Hg19::chr6:154360476..154360504,+p2@OPRM1
Hg19::chr6:154360522..154360525,+p14@OPRM1
Hg19::chr6:154360530..154360549,+p3@OPRM1
Hg19::chr6:154360553..154360567,+p4@OPRM1
Hg19::chr7:133694696..133694724,+p16@EXOC4
Hg19::chr7:19185493..19185503,-p2@FERD3L
Hg19::chr7:73919759..73919766,-p@chr7:73919759..73919766
-
Hg19::chr7:73919790..73919798,-p@chr7:73919790..73919798
-
Hg19::chr7:73919799..73919805,-p@chr7:73919799..73919805
-
Hg19::chr7:8276508..8276551,-p14@ICA1
Hg19::chr7:8276855..8276873,+p@chr7:8276855..8276873
+
Hg19::chr7:8301962..8301966,-p17@ICA1
Hg19::chr7:8301975..8301984,-p11@ICA1
Hg19::chr7:8301994..8301997,-p19@ICA1
Hg19::chr7:8302002..8302015,-p10@ICA1
Hg19::chr7:8302097..8302104,-p15@ICA1
Hg19::chr7:8302126..8302136,-p12@ICA1
Hg19::chr7:8302298..8302323,-p9@ICA1
Hg19::chr8:13373093..13373105,-p55@DLC1
Hg19::chr8:142878006..142878015,+p@chr8:142878006..142878015
+
Hg19::chr8:73164078..73164082,-p6@LOC392232
Hg19::chr9:136501478..136501491,+p1@DBH
Hg19::chr9:137605204..137605213,+p@chr9:137605204..137605213
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0032989cellular structure morphogenesis0.012351859015746
GO:0000902cell morphogenesis0.012351859015746
GO:0032501multicellular organismal process0.012351859015746
GO:0030141secretory granule0.012351859015746
GO:0032990cell part morphogenesis0.012351859015746
GO:0048858cell projection morphogenesis0.012351859015746
GO:0030030cell projection organization and biogenesis0.012351859015746
GO:0005333norepinephrine transmembrane transporter activity0.0185446838572942
GO:0005334norephinephrine:sodium symporter activity0.0185446838572942
GO:0042583chromaffin granule0.0185446838572942
GO:0015874norepinephrine transport0.0185446838572942
GO:0007268synaptic transmission0.0200921373067378
GO:0050877neurological system process0.0226023037666984
GO:0019226transmission of nerve impulse0.0233722017898953
GO:0006836neurotransmitter transport0.0233722017898953
GO:0009914hormone transport0.023991938083013
GO:0050774negative regulation of dendrite morphogenesis0.023991938083013
GO:0015370solute:sodium symporter activity0.0247353766381847
GO:0048814regulation of dendrite morphogenesis0.0291244924816904
GO:0004988mu-opioid receptor activity0.0291244924816904
GO:0030672synaptic vesicle membrane0.0291244924816904
GO:0003008system process0.0293082164144434
GO:0006887exocytosis0.0293082164144434
GO:0015294solute:cation symporter activity0.0293082164144434
GO:0050773regulation of dendrite development0.0293082164144434
GO:0048813dendrite morphogenesis0.0293082164144434
GO:0048667neuron morphogenesis during differentiation0.0293082164144434
GO:0048812neurite morphogenesis0.0293082164144434
GO:0000904cellular morphogenesis during differentiation0.0311410238356019
GO:0032502developmental process0.0313272232327204
GO:0048265response to pain0.0313272232327204
GO:0008504monoamine transmembrane transporter activity0.0313272232327204
GO:0031175neurite development0.0313272232327204
GO:0009653anatomical structure morphogenesis0.0342713320105026
GO:0015844monoamine transport0.0349185433074233
GO:0048666neuron development0.0371398780115165
GO:0030667secretory granule membrane0.0385248908208417
GO:0008508bile acid:sodium symporter activity0.0417582874367942
GO:0004500dopamine beta-monooxygenase activity0.0417582874367942
GO:0042423catecholamine biosynthetic process0.0496224120078445
GO:0015125bile acid transmembrane transporter activity0.0496224120078445



Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
neural cell2.02e-0725
Uber Anatomy
Ontology termp-valuen
regional part of nervous system1.08e-3394
nervous system1.08e-3394
central nervous system1.64e-3182
adult organism7.62e-29115
neural tube2.69e-2757
neural rod2.69e-2757
future spinal cord2.69e-2757
neural keel2.69e-2757
brain2.43e-2469
future brain2.43e-2469
regional part of brain7.85e-2359
regional part of forebrain1.38e-2141
forebrain1.38e-2141
future forebrain1.38e-2141
neurectoderm3.26e-2190
anterior neural tube4.16e-2142
neural plate2.13e-2086
presumptive neural plate2.13e-2086
gray matter1.00e-1834
brain grey matter1.00e-1834
telencephalon2.33e-1834
regional part of telencephalon6.87e-1833
cerebral hemisphere1.41e-1732
ectoderm1.74e-17173
presumptive ectoderm1.74e-17173
ectoderm-derived structure1.11e-16169
pre-chordal neural plate6.28e-1561
cerebral cortex3.00e-1425
pallium3.00e-1425
regional part of cerebral cortex3.36e-1322
neocortex3.37e-1220
head1.96e-10123
anterior region of body2.35e-10129
craniocervical region2.35e-10129
tube1.38e-08194
posterior neural tube2.27e-0715
chordal neural plate2.27e-0715
anatomical conduit4.75e-07241
Disease
Ontology termp-valuen
germ cell and embryonal cancer9.65e-0822
germ cell cancer9.65e-0822


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

"{{{coexpression_dpi_cluster_scores_median}}}" is not a number.

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