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Coexpression cluster:C3959

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Full id: C3959_cerebral_occipital_middle_skeletal_parietal_hippocampus_medial



Phase1 CAGE Peaks

Hg19::chr1:247436728..247436776,+p@chr1:247436728..247436776
+
Hg19::chr1:6209302..6209306,-p@chr1:6209302..6209306
-
Hg19::chr5:149599188..149599192,-p@chr5:149599188..149599192
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube4.83e-7157
neural rod4.83e-7157
future spinal cord4.83e-7157
neural keel4.83e-7157
regional part of forebrain3.31e-6641
forebrain3.31e-6641
future forebrain3.31e-6641
anterior neural tube2.20e-6442
regional part of brain3.12e-6259
gray matter3.24e-6034
brain grey matter3.24e-6034
neural plate4.13e-6086
presumptive neural plate4.13e-6086
telencephalon4.30e-6034
central nervous system3.60e-5982
brain1.42e-5869
future brain1.42e-5869
regional part of telencephalon5.18e-5833
neurectoderm9.36e-5790
cerebral hemisphere1.78e-5632
regional part of nervous system1.83e-5394
nervous system1.83e-5394
adult organism4.76e-52115
pre-chordal neural plate2.43e-5061
regional part of cerebral cortex3.86e-4522
cerebral cortex2.06e-4225
pallium2.06e-4225
neocortex1.01e-4020
head2.68e-39123
anterior region of body2.13e-38129
craniocervical region2.13e-38129
ectoderm-derived structure1.15e-35169
ectoderm1.90e-34173
presumptive ectoderm1.90e-34173
basal ganglion3.52e-199
nuclear complex of neuraxis3.52e-199
aggregate regional part of brain3.52e-199
collection of basal ganglia3.52e-199
cerebral subcortex3.52e-199
nucleus of brain5.40e-199
neural nucleus5.40e-199
telencephalic nucleus3.60e-157
organ part6.62e-15219
tube9.79e-15194
gyrus2.00e-146
anatomical conduit4.00e-14241
temporal lobe4.73e-147
organism subdivision1.13e-13365
epithelium1.27e-12309
cell layer2.41e-12312
parietal lobe4.56e-125
limbic system4.66e-125
occipital lobe8.46e-125
anatomical cluster1.65e-11286
multi-tissue structure7.86e-10347
posterior neural tube1.41e-0915
chordal neural plate1.41e-0915
corpus striatum1.65e-094
striatum1.65e-094
ventral part of telencephalon1.65e-094
future corpus striatum1.65e-094
segmental subdivision of nervous system3.20e-0913
brainstem5.74e-098
organ2.87e-08511
middle temporal gyrus3.10e-083
diencephalon6.63e-087
future diencephalon6.63e-087
embryo9.36e-08612
segmental subdivision of hindbrain1.04e-0712
hindbrain1.04e-0712
presumptive hindbrain1.04e-0712
caudate-putamen1.70e-073
dorsal striatum1.70e-073
brainstem nucleus2.92e-073
pons2.99e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.