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{{Coexpression_clusters
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|full_id=C1859_occipital_Neural_parietal_temporal_teratocarcinoma_brain_duodenum
|id=C1859
|ontology_enrichment_celltype=CL:0000047!6.85e-08!8
|ontology_enrichment_disease=DOID:3095!3.58e-07!22;DOID:2994!3.58e-07!22
|ontology_enrichment_uberon=UBERON:0000073!1.70e-40!94;UBERON:0001016!1.70e-40!94;UBERON:0005743!8.58e-40!86;UBERON:0002346!1.27e-38!90;UBERON:0001017!9.07e-38!82;UBERON:0003075!2.98e-36!86;UBERON:0007284!2.98e-36!86;UBERON:0001049!5.77e-34!57;UBERON:0005068!5.77e-34!57;UBERON:0006241!5.77e-34!57;UBERON:0007135!5.77e-34!57;UBERON:0007023!1.92e-33!115;UBERON:0000955!2.30e-28!69;UBERON:0006238!2.30e-28!69;UBERON:0002616!3.94e-28!59;UBERON:0002780!1.35e-25!41;UBERON:0001890!1.35e-25!41;UBERON:0006240!1.35e-25!41;UBERON:0000924!2.28e-25!173;UBERON:0006601!2.28e-25!173;UBERON:0003056!2.87e-25!61;UBERON:0003080!1.39e-24!42;UBERON:0001893!1.49e-24!34;UBERON:0002020!3.29e-24!34;UBERON:0003528!3.29e-24!34;UBERON:0002791!9.72e-24!33;UBERON:0001869!1.35e-23!32;UBERON:0004121!1.78e-23!169;UBERON:0000033!5.63e-21!123;UBERON:0000153!1.84e-20!129;UBERON:0007811!1.84e-20!129;UBERON:0000956!5.88e-20!25;UBERON:0000203!5.88e-20!25;UBERON:0002619!2.27e-17!22;UBERON:0001950!1.01e-15!20;UBERON:0000475!3.15e-12!365;UBERON:0000468!3.58e-12!659;UBERON:0003076!2.05e-10!15;UBERON:0003057!2.05e-10!15;UBERON:0000025!4.19e-09!194;UBERON:0004732!7.35e-09!13;UBERON:0004733!2.28e-08!12;UBERON:0002028!2.28e-08!12;UBERON:0007277!2.28e-08!12;UBERON:0000467!2.75e-08!625;UBERON:0000480!3.54e-08!626;UBERON:0000064!5.20e-08!219;UBERON:0000062!5.26e-08!511;UBERON:0004111!2.46e-07!241;UBERON:0003135!4.22e-07!11;UBERON:0001871!9.50e-07!7
}}

Latest revision as of 11:53, 17 September 2013


Full id: C1859_occipital_Neural_parietal_temporal_teratocarcinoma_brain_duodenum



Phase1 CAGE Peaks

Hg19::chr1:57888776..57888794,-p11@DAB1
Hg19::chr1:57888869..57888890,-p4@DAB1
Hg19::chr1:57889687..57889754,-p2@DAB1
Hg19::chr1:57889755..57889770,-p9@DAB1
Hg19::chr1:57889993..57890012,-p12@DAB1


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br>disease_data<br>

Cell Type
Ontology termp-valuen
neuronal stem cell1.41e-098
neural cell3.26e-0925
neurectodermal cell9.66e-0959
embryonic stem cell4.79e-075
oligodendrocyte5.74e-077
macroglial cell5.74e-077
astrocyte5.74e-077
oligodendrocyte precursor cell5.74e-077
neuron8.17e-076
neuroblast8.17e-076
electrically signaling cell8.17e-076
Uber Anatomy
Ontology termp-valuen
central nervous system3.21e-5181
nervous system9.03e-5089
neurectoderm1.16e-4386
neural tube4.58e-4356
neural rod4.58e-4356
future spinal cord4.58e-4356
neural keel4.58e-4356
neural plate4.35e-4182
presumptive neural plate4.35e-4182
regional part of nervous system9.46e-4053
regional part of brain9.46e-4053
brain7.22e-3868
future brain7.22e-3868
regional part of forebrain4.24e-3141
forebrain4.24e-3141
anterior neural tube4.24e-3141
future forebrain4.24e-3141
pre-chordal neural plate1.45e-3061
ectoderm-derived structure2.79e-30171
ectoderm2.79e-30171
presumptive ectoderm2.79e-30171
telencephalon4.08e-3034
brain grey matter1.56e-2934
gray matter1.56e-2934
ecto-epithelium1.91e-28104
cerebral hemisphere3.32e-2832
regional part of telencephalon7.21e-2832
adult organism3.44e-27114
structure with developmental contribution from neural crest1.19e-25132
cerebral cortex1.98e-2525
pallium1.98e-2525
regional part of cerebral cortex2.30e-2122
neocortex8.47e-1920
organ system subdivision3.30e-17223
posterior neural tube8.10e-1315
chordal neural plate8.10e-1315
multi-cellular organism6.57e-10656
segmental subdivision of hindbrain1.06e-0912
hindbrain1.06e-0912
presumptive hindbrain1.06e-0912
anatomical cluster6.55e-09373
segmental subdivision of nervous system9.12e-0913
regional part of metencephalon1.21e-089
metencephalon1.21e-089
future metencephalon1.21e-089
limbic system4.38e-085
parietal lobe7.34e-085
tube2.00e-07192
temporal lobe4.85e-076
Disease
Ontology termp-valuen
germ cell and embryonal cancer9.27e-0722
germ cell cancer9.27e-0722


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.14.3611
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.11.45664
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.10.569896
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.0853006
MA0056.10
MA0057.13.13944
MA0058.10.523638
MA0059.10.522232
MA0060.10.321781
MA0061.10.291022
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.19.30851
MA0074.11.73427
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.12.58868
MA0089.10
MA0090.11.36977
MA0091.10.629594
MA0092.10.588959
MA0093.10.456342
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.10.459973
MA0103.10.442769
MA0105.10.520776
MA0106.11.83541
MA0107.10.378225
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.759606
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.442008
MA0146.11.35428
MA0147.10.386018
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.21.12758
MA0138.20.837782
MA0002.20.83106
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.425004
MA0065.20.146576
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.172764
MA0155.10.130813
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.12.27598
MA0163.12.54221
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.26.20913
MA0102.21.66336
MA0258.10.345771
MA0259.10.395396
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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