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MCL coexpression mm9:1169: Difference between revisions

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{{MCL_coexpression_mm9
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transporter activity;0.00443738356052032;27411!GO:0015204;urea transmembrane transporter activity;0.00443738356052032;27411!GO:0015840;urea transport;0.00443738356052032;27411!GO:0042886;amide transport;0.00443738356052032;27411!GO:0051219;phosphoprotein binding;0.023060490470473;26913!|ontology_enrichment_celltype=CL:0000117!1.47e-19!23;CL:0000337!1.47e-19!23;CL:0000540!2.13e-11!33;CL:0000047!2.13e-11!33;CL:0000031!2.13e-11!33;CL:0000404!2.13e-11!33;CL:0000393!1.34e-08!39;CL:0000211!1.34e-08!39;CL:0002609!3.50e-08!6;CL:0002319!6.57e-08!43;CL:0000221!1.40e-07!44;CL:0000133!1.40e-07!44|ontology_enrichment_disease=|ontology_enrichment_uberon=UBERON:0002346!5.90e-17!64;UBERON:0003075!5.90e-17!64;UBERON:0007284!5.90e-17!64;UBERON:0003056!6.20e-16!49;UBERON:0001049!1.50e-14!52;UBERON:0005068!1.50e-14!52;UBERON:0006241!1.50e-14!52;UBERON:0007135!1.50e-14!52;UBERON:0000073!1.42e-13!54;UBERON:0002020!2.06e-13!34;UBERON:0010371!2.50e-13!73;UBERON:0002780!9.97e-13!39;UBERON:0001890!9.97e-13!39;UBERON:0006240!9.97e-13!39;UBERON:0003080!3.33e-12!40;UBERON:0001017!9.68e-12!73;UBERON:0004121!2.32e-11!95;UBERON:0000924!2.32e-11!95;UBERON:0006601!2.32e-11!95;UBERON:0001016!4.00e-11!75;UBERON:0002616!2.41e-10!46;UBERON:0000955!5.95e-10!47;UBERON:0006238!5.95e-10!47;UBERON:0003528!1.94e-09!29;UBERON:0002791!1.94e-09!29;UBERON:0001893!1.94e-09!29;UBERON:0010314!1.00e-08!92;UBERON:0002420!8.81e-07!8;UBERON:0007245!8.81e-07!8;UBERON:0010009!8.81e-07!8;UBERON:0010011!8.81e-07!8;UBERON:0000454!8.81e-07!8|tfbs_overrepresentation_for_novel_motifs=0.438063,0.0418382,0.411716,0.480627,0.810002,0.495263,0.587291,1.12275,0.215218,0.478312,0.542749,0.575086,0.59526,0.599731,0.315771,0,0.795315,0.792229,0.561256,0.112498,0.978328,0.586604,0.598814,0.29769,0.419327,0.62766,0.542568,0.516511,0.344372,0.145661,0.50223,0.897561,0.78719,0.498917,0.316253,0.248902,0.279977,0.57142,0.258564,0.652422,0.295233,0.507468,0.54842,0.317766,0.515031,0.469348,0.714592,0.532496,0.219744,0.917701,0.777641,0.654933,0.851157,1.04034,1.0579,0.606984,0.356236,0.56214,0.176152,0.604914,0.877332,0.664501,1.87045,0.766235,0.618279,1.89163,1.19497,1.54543,0.872612,1.39786,0.392734,0.21183,0.0869413,1.09164,0.17012,0.482617,0.166511,0.703064,0.859987,0.378988,0.610783,0.812889,0.663039,0.200155,0.975495,0.0369809,0.667407,0.447265,0.719558,1.70793,1.26498,0.980512,0.910485,1.49196,0.254625,0.237542,0.203879,0.913319,0.71485,0.127063,0.280055,0.897279,1.02279,0.778243,0.777175,0.507021,0.837607,0.528416,0.383871,0.376549,0.430942,1.02459,0.990132,0.547992,1.27206,0.293461,0.187586,0.484437,0.796633,0.276329,1.09707,0.745011,0.629509,0.702145,1.32639,0.863723,0.595563,0.903645,1.19345,0.308038,1.00568,0.473246,1.16374,0.620831,1.29374,0.0806013,0.446555,0.508896,1.24438,2.07659,1.67603,1.19971,0.641722,0.908128,0.770616,0.507927,0.717753,2.03691,2.9597,0.300961,0.452587,0.0736236,1.04192,0.243291,0.619892,4.12533,0.655955,0.327731,1.11101,0.446272,1.25393,0.974632,0.864173,0.428662,0.767269,0.612377,0.763807,0.573477,0.433127|tfbs_overrepresentation_jaspar=MA0003.1;0.0861444,MA0004.1;0.481116,MA0006.1;0.311391,MA0007.1;0.465969,MA0009.1;0.92425,MA0014.1;0.0886247,MA0017.1;0.337808,MA0019.1;0.740036,MA0024.1;0.880057,MA0025.1;1.15921,MA0027.1;2.57545,MA0028.1;0.321735,MA0029.1;0.858105,MA0030.1;0.864739,MA0031.1;0.828781,MA0038.1;0.62758,MA0040.1;0.936879,MA0041.1;0.404721,MA0042.1;0.391504,MA0043.1;1.02178,MA0046.1;0.960497,MA0048.1;0.128106,MA0050.1;0.520357,MA0051.1;0.636645,MA0052.1;0.945011,MA0055.1;0.0406078,MA0056.1;0,MA0057.1;0.376102,MA0058.1;0.384683,MA0059.1;0.397033,MA0060.1;0.656954,MA0061.1;0.261749,MA0063.1;0,MA0066.1;0.616444,MA0067.1;1.27078,MA0068.1;0.771749,MA0069.1;0.945354,MA0070.1;0.93557,MA0071.1;0.519509,MA0072.1;0.927016,MA0073.1;0.351935,MA0074.1;0.580087,MA0076.1;0.356883,MA0077.1;0.905143,MA0078.1;0.670113,MA0081.1;0.420276,MA0083.1;1.02098,MA0084.1;1.59945,MA0087.1;0.977537,MA0088.1;0.0841779,MA0089.1;0,MA0090.1;0.446539,MA0091.1;2.14241,MA0092.1;0.446857,MA0093.1;0.329976,MA0095.1;0,MA0098.1;0,MA0100.1;0.568369,MA0101.1;0.406019,MA0103.1;0.348572,MA0105.1;0.162418,MA0106.1;0.677988,MA0107.1;0.342432,MA0108.2;0.763162,MA0109.1;0,MA0111.1;0.460823,MA0113.1;0.649407,MA0114.1;0.259463,MA0115.1;1.0246,MA0116.1;0.311187,MA0117.1;0.992087,MA0119.1;4.85978,MA0122.1;2.31065,MA0124.1;1.21735,MA0125.1;1.14291,MA0130.1;0,MA0131.1;0.735438,MA0132.1;0,MA0133.1;0,MA0135.1;1.05845,MA0136.1;0.600242,MA0139.1;0.202522,MA0140.1;1.3943,MA0141.1;0.368264,MA0142.1;0.814115,MA0143.1;0.665982,MA0144.1;0.262477,MA0145.1;0.0910975,MA0146.1;0.0256827,MA0147.1;0.274511,MA0148.1;0.49752,MA0149.1;0.411562,MA0062.2;0.167299,MA0035.2;2.40034,MA0039.2;0.014361,MA0138.2;0.727395,MA0002.2;0.205289,MA0137.2;0.365364,MA0104.2;0.218974,MA0047.2;0.626803,MA0112.2;0.0910939,MA0065.2;0.0914071,MA0150.1;0.465855,MA0151.1;0,MA0152.1;0.626912,MA0153.1;1.07519,MA0154.1;0.397336,MA0155.1;0.102995,MA0156.1;0.356017,MA0157.1;0.781683,MA0158.1;0,MA0159.1;0.284457,MA0160.1;0.50056,MA0161.1;0,MA0162.1;0.127623,MA0163.1;0.28052,MA0164.1;0.600609,MA0080.2;0.343316,MA0018.2;0.610433,MA0099.2;0.721008,MA0079.2;0.00878868,MA0102.2;1.65195,MA0258.1;0.246285,MA0259.1;0.26402,MA0442.1;0}}
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|gostat_on_MCL_coexpression=GO:0042887;amide transporter activity;0.00443738356052032;27411!GO:0015204;urea transmembrane transporter activity;0.00443738356052032;27411!GO:0015840;urea transport;0.00443738356052032;27411!GO:0042886;amide transport;0.00443738356052032;27411!GO:0051219;phosphoprotein binding;0.023060490470473;26913!
}}

Latest revision as of 16:30, 17 September 2013


Phase1 CAGE Peaks

 Short description
Mm9::chr18:78402606..78402617,-p7@Slc14a2
Mm9::chr18:78402628..78402656,-p4@Slc14a2
Mm9::chr18:78402660..78402716,-p2@Slc14a2
Mm9::chr2:25160647..25160666,-p3@Grin1
Mm9::chr2:4073634..4073656,+p32@Frmd4a
Mm9::chr9:58050108..58050129,-p17@Islr2
Mm9::chr9:58050554..58050579,-p15@Islr2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0042887amide transporter activity0.00443738356052032
GO:0015204urea transmembrane transporter activity0.00443738356052032
GO:0015840urea transport0.00443738356052032
GO:0042886amide transport0.00443738356052032
GO:0051219phosphoprotein binding0.023060490470473



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
neurectoderm5.90e-1764
neural plate5.90e-1764
presumptive neural plate5.90e-1764
pre-chordal neural plate6.20e-1649
neural tube1.50e-1452
neural rod1.50e-1452
future spinal cord1.50e-1452
neural keel1.50e-1452
regional part of nervous system1.42e-1354
gray matter2.06e-1334
ecto-epithelium2.50e-1373
regional part of forebrain9.97e-1339
forebrain9.97e-1339
future forebrain9.97e-1339
anterior neural tube3.33e-1240
central nervous system9.68e-1273
ectoderm-derived structure2.32e-1195
ectoderm2.32e-1195
presumptive ectoderm2.32e-1195
nervous system4.00e-1175
regional part of brain2.41e-1046
brain5.95e-1047
future brain5.95e-1047
brain grey matter1.94e-0929
regional part of telencephalon1.94e-0929
telencephalon1.94e-0929
structure with developmental contribution from neural crest1.00e-0892
basal ganglion8.81e-078
nuclear complex of neuraxis8.81e-078
aggregate regional part of brain8.81e-078
collection of basal ganglia8.81e-078
cerebral subcortex8.81e-078


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)
MA0003.10.0861444
MA0004.10.481116
MA0006.10.311391
MA0007.10.465969
MA0009.10.92425
MA0014.10.0886247
MA0017.10.337808
MA0019.10.740036
MA0024.10.880057
MA0025.11.15921
MA0027.12.57545
MA0028.10.321735
MA0029.10.858105
MA0030.10.864739
MA0031.10.828781
MA0038.10.62758
MA0040.10.936879
MA0041.10.404721
MA0042.10.391504
MA0043.11.02178
MA0046.10.960497
MA0048.10.128106
MA0050.10.520357
MA0051.10.636645
MA0052.10.945011
MA0055.10.0406078
MA0056.10
MA0057.10.376102
MA0058.10.384683
MA0059.10.397033
MA0060.10.656954
MA0061.10.261749
MA0063.10
MA0066.10.616444
MA0067.11.27078
MA0068.10.771749
MA0069.10.945354
MA0070.10.93557
MA0071.10.519509
MA0072.10.927016
MA0073.10.351935
MA0074.10.580087
MA0076.10.356883
MA0077.10.905143
MA0078.10.670113
MA0081.10.420276
MA0083.11.02098
MA0084.11.59945
MA0087.10.977537
MA0088.10.0841779
MA0089.10
MA0090.10.446539
MA0091.12.14241
MA0092.10.446857
MA0093.10.329976
MA0095.10
MA0098.10
MA0100.10.568369
MA0101.10.406019
MA0103.10.348572
MA0105.10.162418
MA0106.10.677988
MA0107.10.342432
MA0108.20.763162
MA0109.10
MA0111.10.460823
MA0113.10.649407
MA0114.10.259463
MA0115.11.0246
MA0116.10.311187
MA0117.10.992087
MA0119.14.85978
MA0122.12.31065
MA0124.11.21735
MA0125.11.14291
MA0130.10
MA0131.10.735438
MA0132.10
MA0133.10
MA0135.11.05845
MA0136.10.600242
MA0139.10.202522
MA0140.11.3943
MA0141.10.368264
MA0142.10.814115
MA0143.10.665982
MA0144.10.262477
MA0145.10.0910975
MA0146.10.0256827
MA0147.10.274511
MA0148.10.49752
MA0149.10.411562
MA0062.20.167299
MA0035.22.40034
MA0039.20.014361
MA0138.20.727395
MA0002.20.205289
MA0137.20.365364
MA0104.20.218974
MA0047.20.626803
MA0112.20.0910939
MA0065.20.0914071
MA0150.10.465855
MA0151.10
MA0152.10.626912
MA0153.11.07519
MA0154.10.397336
MA0155.10.102995
MA0156.10.356017
MA0157.10.781683
MA0158.10
MA0159.10.284457
MA0160.10.50056
MA0161.10
MA0162.10.127623
MA0163.10.28052
MA0164.10.600609
MA0080.20.343316
MA0018.20.610433
MA0099.20.721008
MA0079.20.00878868
MA0102.21.65195
MA0258.10.246285
MA0259.10.26402
MA0442.10
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