FF:12750-136A5: Difference between revisions
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{{f5samples | {{f5samples | ||
|ancestors_in_anatomy_facet=UBERON: | |DRA_sample_Accession=CAGE@SAMD00005935 | ||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL: | |accession_numbers=CAGE;DRX008582;DRR009454;DRZ000879;DRZ002264;DRZ012229;DRZ013614 | ||
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0001135,UBERON:0000947,UBERON:0001637,UBERON:0000483,UBERON:0000479,UBERON:0000055,UBERON:0004111,UBERON:0004120,UBERON:0000061,UBERON:0000465,UBERON:0003914,UBERON:0000025,UBERON:0000477,UBERON:0000467,UBERON:0001062,UBERON:0000480,UBERON:0000119,UBERON:0004573,UBERON:0002385,UBERON:0003509,UBERON:0007500,UBERON:0001981,UBERON:0004237,UBERON:0004695,UBERON:0002049,UBERON:0010317,UBERON:0002111,UBERON:0007798,UBERON:0001015,UBERON:0004178,UBERON:0002204,UBERON:0004535,UBERON:0004571,UBERON:0010191,UBERON:0000383,UBERON:0004572,UBERON:0004537,UBERON:0001009 | |||
|ancestors_in_cell_lineage_facet=CL:0000000,CL:0000003,CL:0000548,CL:0002371,CL:0000393,CL:0000183,CL:0000187,CL:0000192,CL:0000211,CL:0000255,CL:0000359,CL:0002539 | |||
|ancestors_in_disease_facet= | |ancestors_in_disease_facet= | ||
|ancestors_in_ff_facet=FF:0000210,FF:0000101,FF:0000001,FF:0000350,FF:0000344,FF:0000340,FF:0000556 | |||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
|creation_date= | |creation_date= | ||
|data_phase=2 | |||
|datafreeze_phase=2 | |||
|def= | |def= | ||
|donor=biol_rep2 (LK32) | |||
|expression_enrichment_score=chr8:55370487..55370503,+!p1@SOX17!2.05!110.27!SOX17;;chr21:38071430..38071456,+!p1@SIM2!1.76!56.60!SIM2;;chr12:66218836..66218888,+!p1@HMGA2!1.46!248.85!HMGA2;;chr14:29235961..29236008,+!p1@FOXG1!1.39!23.42!FOXG1;;chr1:170633348..170633399,+!p2@PRRX1!1.33!27.81!PRRX1;;chr1:170632285..170632309,+!p1@PRRX1!1.29!20.98!PRRX1;;chr14:29234581..29234601,+!p2@FOXG1!1.26!17.08!FOXG1;;chr10:94449703..94449718,+!p1@HHEX!1.25!63.43!HHEX;;chr12:66218904..66218913,+!p11@HMGA2!1.25!16.59!HMGA2;;chr11:34642612..34642646,+!p1@EHF!1.23!16.10!EHF;;chr12:66218923..66218934,+!p14@HMGA2!1.23!16.10!HMGA2;;chr17:1959369..1959388,+!p2@HIC1!1.21!40.01!HIC1;;chr8:11561684..11561751,+!p1@GATA4!1.18!14.15!GATA4;;chr12:66218598..66218645,+!p2@HMGA2!1.17!63.43!HMGA2;;chr14:29236269..29236285,+!p3@FOXG1!1.17!13.66!FOXG1;;chr1:170633262..170633285,+!p3@PRRX1!1.14!14.64!PRRX1;;chr12:66358080..66358094,+!p15@HMGA2!1.12!12.20!HMGA2;;chr11:46299199..46299233,+!p1@CREB3L1!1.10!60.02!CREB3L1;;chr17:46622205..46622218,-!p3@HOXB2!1.09!13.17!HOXB2;;chr16:86544113..86544145,+!p1@FOXF1!1.08!13.66!FOXF1;;chr12:66218255..66218304,+!p3@HMGA2!1.05!27.81!HMGA2;;chr1:170632959..170632987,+!p4@PRRX1!1.05!11.22!PRRX1;;chr3:141087393..141087426,+!p3@ZBTB38!1.04!40.50!ZBTB38;;chr2:19558373..19558392,-!p1@OSR1!0.99!24.40!OSR1;;chr1:170633058..170633084,+!p5@PRRX1!0.99!8.78!PRRX1;;chr5:72744594..72744609,-!p1@FOXD1!0.98!40.50!FOXD1;;chr2:239756671..239756732,+!p1@TWIST2!0.98!27.81!TWIST2;;chr12:66218212..66218244,+!p5@HMGA2!0.97!12.20!HMGA2;;chr1:170632115..170632136,+!p9@PRRX1!0.97!8.29!PRRX1;;chr11:61520075..61520136,+!p1@C11orf9!0.96!17.57!C11orf9;;chr17:46655704..46655718,-!p2@HOXB4!0.96!12.20!HOXB4;;chrY:2803415..2803468,+!p1@ZFY!0.94!7.81!ZFY;;chr3:141105705..141105770,+!p4@ZBTB38!0.93!9.27!ZBTB38;;chr19:42636586..42636607,-!p1@POU2F2!0.92!20.98!POU2F2;;chr11:46299539..46299620,+!p2@CREB3L1!0.89!11.71!CREB3L1;;chr21:38071462..38071474,+!p3@SIM2!0.89!6.83!SIM2;;chr7:27183291..27183324,-!p1@HOXA5!0.89!6.83!HOXA5;;chr17:1958388..1958404,+!p1@HIC1!0.88!43.91!HIC1;;chr17:46622070..46622109,-!p1@HOXB2!0.88!15.13!HOXB2;;chr17:46688334..46688385,-!p1@HOXB7!0.88!9.76!HOXB7;;chr17:46621937..46621966,-!p2@HOXB2!0.87!18.05!HOXB2;;chr1:221052840..221052875,+!p4@HLX!0.87!7.81!HLX;;chr21:38071403..38071428,+!p2@SIM2!0.87!6.34!SIM2;;chr1:221052776..221052799,+!p1@HLX!0.86!11.71!HLX;;chr1:170632439..170632465,+!p11@PRRX1!0.84!5.86!PRRX1;;chr6:134210243..134210257,+!p1@TCF21!0.84!5.86!TCF21;;chr20:50721803..50721857,-!p2@ZFP64!0.83!9.27!ZFP64;;chr18:53068911..53068935,-!p4@TCF4!0.82!6.34!TCF4;;chr6:34204921..34204939,+!p3@HMGA1!0.80!174.68!HMGA1;;chr20:42543441..42543497,+!p1@TOX2!0.80!25.86!TOX2;;chr5:321810..321877,+!p1@AHRR!0.80!18.05!AHRR;;chr17:41622925..41622976,-!p3@ETV4!0.80!8.29!ETV4;;chr17:46659728..46659749,-!p3@HOXB3!0.80!5.37!HOXB3;;chr1:170632137..170632172,+!p10@PRRX1!0.80!5.37!PRRX1;;chr1:170632477..170632506,+!p6@PRRX1!0.80!5.37!PRRX1;;chr1:170632683..170632696,+!p12@PRRX1!0.80!5.37!PRRX1;;chr1:170632723..170632739,+!p8@PRRX1!0.80!5.37!PRRX1;;chr1:151032860..151032918,+!p1@MLLT11!0.79!67.33!MLLT11;;chr20:42543506..42543549,+!p2@TOX2!0.79!13.17!TOX2;;chr20:6748325..6748352,+!p1@BMP2!0.79!7.81!BMP2;;chr12:125002739..125002756,-!p6@NCOR2!0.78!7.81!NCOR2;;chr17:46675420..46675465,-!p3@HOXB6!0.78!5.86!HOXB6;;chr6:45296048..45296082,+!p1@RUNX2!0.78!5.86!RUNX2;;chr15:96869255..96869291,+!p6@NR2F2!0.77!9.27!NR2F2;;chr17:46622114..46622138,-!p4@HOXB2!0.77!7.81!HOXB2;;chr8:55370720..55370733,+!p2@SOX17!0.77!4.88!SOX17;;chr12:66218183..66218209,+!p4@HMGA2!0.76!9.76!HMGA2;;chr2:66662281..66662308,+!p1@MEIS1!0.75!17.57!MEIS1;;chr15:83953397..83953425,-!p1@BNC1!0.75!5.37!BNC1;;chr3:157823517..157823562,-!p1@SHOX2!0.74!4.88!SHOX2;;chr1:170632028..170632043,+!p20@PRRX1!0.73!4.39!PRRX1;;chr1:170632647..170632659,+!p17@PRRX1!0.73!4.39!PRRX1;;chr17:46621146..46621180,-!p10@HOXB2!0.73!4.39!HOXB2;;chrY:21906594..21906622,-!p1@KDM5D!0.73!4.39!KDM5D;;chr17:41622765..41622821,-!p2@ETV4!0.72!6.83!ETV4;;chr5:72744445..72744466,-!p2@FOXD1!0.71!7.32!FOXD1;;chr17:3571863..3571881,-!p1@TAX1BP3!0.70!327.40!TAX1BP3;;chr6:21597514..21597578,+!p4@SOX4!0.70!7.32!SOX4;;chr6:21597370..21597408,+!p5@SOX4!0.70!6.83!SOX4;;chr7:26191809..26191890,+!p1@NFE2L3!0.69!21.96!NFE2L3;;chr15:96869206..96869220,+!p21@NR2F2!0.69!3.90!NR2F2;;chr17:46655672..46655697,-!p3@HOXB4!0.69!3.90!HOXB4;;chr2:102091144..102091183,-!p2@RFX8!0.69!3.90!RFX8;;chr12:66357214..66357233,+!p13@HMGA2!0.69!3.90!HMGA2;;chr14:29236169..29236216,+!p6@FOXG1!0.69!3.90!FOXG1;;chr1:170632250..170632277,+!p7@PRRX1!0.69!3.90!PRRX1;;chr15:57511609..57511651,+!p2@TCF12!0.68!6.83!TCF12;;chr2:66662895..66662907,+!p3@MEIS1!0.68!4.88!MEIS1;;chr11:65686802..65686818,+!p6@DRAP1!0.67!6.83!DRAP1;;chr6:106534192..106534224,+!p1@PRDM1!0.66!11.22!PRDM1;;chr15:96876966..96877017,+!p12@NR2F2!0.66!5.37!NR2F2;;chr1:221052994..221053008,+!p6@HLX!0.66!4.39!HLX;;chr15:96874244..96874259,+!p5@NR2F2!0.65!9.27!NR2F2;;chr3:178789522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| |||
|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000056;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000187;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000192;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0000359;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/CL:0002539;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000947;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001135;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001637;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001981;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002385;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0004573;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0007798 | |||
|ffid_belonging_in_development=CL:0000355,CL:0000222,CL:0000514 | |||
|fonse_cell_line= | |fonse_cell_line= | ||
|fonse_cell_line_closure= | |fonse_cell_line_closure= | ||
Line 34: | Line 43: | ||
|fonse_treatment_closure=EFO:0000369,FF:0000340,FF:0000556,FF:12750-136A5 | |fonse_treatment_closure=EFO:0000369,FF:0000340,FF:0000556,FF:12750-136A5 | ||
|has_quality= | |has_quality= | ||
|hg19bam=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Aortic%2520smooth%2520muscle%2520cell%2520response%2520to%2520IL1b%252c%252000hr00min%252c%2520biol_rep2%2520%2528LK32%2529.CNhs13369.12750-136A5.hg19.nobarcode.bam | |||
|hg19ctss=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Aortic%2520smooth%2520muscle%2520cell%2520response%2520to%2520IL1b%252c%252000hr00min%252c%2520biol_rep2%2520%2528LK32%2529.CNhs13369.12750-136A5.hg19.ctss.bed.gz | |||
|hg19fasta=http://fantom.gsc.riken.jp/5/datafiles/latest/basic/human.timecourse.hCAGE/Aortic%2520smooth%2520muscle%2520cell%2520response%2520to%2520IL1b%252c%252000hr00min%252c%2520biol_rep2%2520%2528LK32%2529.CNhs13369.12750-136A5.hg19.nobarcode.rdna.fa.gz | |||
|hg38bam=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Aortic%2520smooth%2520muscle%2520cell%2520response%2520to%2520IL1b%252c%252000hr00min%252c%2520biol_rep2%2520%2528LK32%2529.CNhs13369.12750-136A5.hg38.nobarcode.bam | |||
|hg38ctss=http://fantom.gsc.riken.jp/5/datafiles/reprocessed/hg38_v2/basic/human.timecourse.hCAGE/Aortic%2520smooth%2520muscle%2520cell%2520response%2520to%2520IL1b%252c%252000hr00min%252c%2520biol_rep2%2520%2528LK32%2529.CNhs13369.12750-136A5.hg38.nobarcode.ctss.bed.gz | |||
|id=FF:12750-136A5 | |id=FF:12750-136A5 | ||
|is_a=EFO:0002091;;FF: | |is_a=EFO:0002091;;FF:0000556 | ||
|name=Aortic smooth muscle cell response to IL1b | |is_obsolete= | ||
|library_id=CNhs13369 | |||
|library_id_phase_based=2:CNhs13369 | |||
|microRNAs= | |||
|microRNAs_nn= | |||
|microRNAs_nonnovel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer/#/human#cage;sample;12750 | |||
|microRNAs_novel_cage=http://fantom.gsc.riken.jp/5/suppl/De_Rie_et_al_2017/vis_viewer_novel/#/human#cage;sample;12750 | |||
|name=Aortic smooth muscle cell response to IL1b | |||
|namespace=FANTOM5 | |namespace=FANTOM5 | ||
|part_of= | |part_of= | ||
|profile_cagescan=,,, | |profile_cagescan=,,, | ||
|profile_hcage=CNhs13369,LSID1022,release013,COMPLETED | |profile_hcage=CNhs13369,LSID1022,release013,COMPLETED | ||
|profile_rnaseq= | |profile_rnaseq= | ||
|profile_srnaseq=,,, | |profile_srnaseq=,,, | ||
|refex=http://refex.dbcls.jp/genelist.php?lang | |||
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| |||
|rna_box=136 | |rna_box=136 | ||
|rna_catalog_number= | |rna_catalog_number= | ||
Line 56: | Line 80: | ||
|rna_weight_ug=3.28 | |rna_weight_ug=3.28 | ||
|sample_age= | |sample_age= | ||
|sample_category=time courses | |||
|sample_cell_catalog= | |sample_cell_catalog= | ||
|sample_cell_line= | |sample_cell_line= | ||
Line 68: | Line 93: | ||
|sample_ethnicity= | |sample_ethnicity= | ||
|sample_experimental_condition=Aortic smooth muscle cell response to interleukin 1b | |sample_experimental_condition=Aortic smooth muscle cell response to interleukin 1b | ||
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;1.27005015015446e-204!GO:0005737;cytoplasm;5.20610761959625e-196!GO:0043226;organelle;1.99652025651156e-157!GO:0043229;intracellular organelle;5.17682175225613e-157!GO:0043231;intracellular membrane-bound organelle;5.97734847248211e-154!GO:0043227;membrane-bound organelle;5.97734847248211e-154!GO:0044444;cytoplasmic part;6.94199737148311e-148!GO:0044422;organelle part;2.18315138830685e-122!GO:0044446;intracellular organelle part;1.43113393233226e-120!GO:0032991;macromolecular complex;1.41337054942053e-89!GO:0030529;ribonucleoprotein complex;6.90864650850739e-85!GO:0005515;protein binding;5.80215863678717e-77!GO:0044238;primary metabolic process;1.58456231498035e-73!GO:0044237;cellular metabolic process;1.65662716916781e-73!GO:0005739;mitochondrion;7.27807201072425e-68!GO:0043170;macromolecule metabolic process;9.44472640838668e-66!GO:0043233;organelle lumen;1.28993338451444e-63!GO:0031974;membrane-enclosed lumen;1.28993338451444e-63!GO:0003723;RNA binding;3.40074093731869e-58!GO:0005840;ribosome;1.172824427713e-54!GO:0019538;protein metabolic process;2.64125951739183e-53!GO:0044428;nuclear part;4.61641010619295e-53!GO:0031090;organelle membrane;6.23833593981633e-53!GO:0006412;translation;1.5192789395533e-50!GO:0044260;cellular macromolecule metabolic process;5.25362889920488e-49!GO:0003735;structural constituent of ribosome;1.12294999125627e-48!GO:0044267;cellular protein metabolic process;6.68636292362286e-48!GO:0044429;mitochondrial part;6.94815891003868e-46!GO:0005829;cytosol;1.28581162047307e-43!GO:0043234;protein complex;1.7957599434151e-43!GO:0033279;ribosomal subunit;6.61516534285091e-43!GO:0016043;cellular component organization and biogenesis;1.04971191762073e-42!GO:0009058;biosynthetic process;1.48115825522019e-42!GO:0005634;nucleus;2.58486648865315e-42!GO:0015031;protein transport;3.18084431640638e-41!GO:0006396;RNA processing;1.1050562367417e-40!GO:0009059;macromolecule biosynthetic process;1.68381858152211e-40!GO:0033036;macromolecule localization;2.0548247139152e-40!GO:0044249;cellular biosynthetic process;7.28767024168198e-40!GO:0045184;establishment of protein localization;2.89549082614633e-38!GO:0008104;protein localization;1.16540636321373e-37!GO:0031967;organelle envelope;1.13760115475745e-36!GO:0031975;envelope;2.57776402013443e-36!GO:0031981;nuclear lumen;6.5889998572089e-35!GO:0046907;intracellular transport;3.78973077090171e-32!GO:0005830;cytosolic ribosome (sensu Eukaryota);4.36074133345288e-32!GO:0016071;mRNA metabolic process;1.06715085554227e-31!GO:0005740;mitochondrial envelope;7.92403968166824e-31!GO:0008380;RNA splicing;1.69006111635126e-30!GO:0043283;biopolymer metabolic process;1.58902110996291e-29!GO:0031966;mitochondrial membrane;9.9279026873421e-29!GO:0010467;gene expression;3.05361185575814e-28!GO:0006397;mRNA processing;1.21264921668133e-27!GO:0065003;macromolecular complex assembly;1.72518149181847e-27!GO:0019866;organelle inner membrane;1.98609675940624e-27!GO:0006886;intracellular protein transport;2.90197686312006e-27!GO:0022613;ribonucleoprotein complex biogenesis and assembly;4.88792521405098e-27!GO:0005743;mitochondrial inner membrane;1.62839895181055e-26!GO:0044445;cytosolic part;6.78490443671321e-26!GO:0005783;endoplasmic reticulum;2.26085636048208e-24!GO:0006119;oxidative phosphorylation;6.10480661304824e-24!GO:0006996;organelle organization and biogenesis;6.69532758211765e-24!GO:0022607;cellular component assembly;8.4525949164782e-24!GO:0043228;non-membrane-bound organelle;8.62465996450738e-23!GO:0043232;intracellular non-membrane-bound organelle;8.62465996450738e-23!GO:0015934;large ribosomal subunit;1.52747685256125e-22!GO:0044455;mitochondrial membrane part;6.09607861362505e-22!GO:0006457;protein folding;1.10848349963127e-21!GO:0012505;endomembrane system;1.19743207437204e-21!GO:0005681;spliceosome;1.71227938236786e-21!GO:0015935;small ribosomal subunit;2.03433516202274e-21!GO:0005654;nucleoplasm;2.32402803199348e-21!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;2.53535220715532e-21!GO:0051641;cellular localization;5.56952531115021e-20!GO:0051649;establishment of cellular localization;5.95226909850297e-20!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;9.7148601953094e-20!GO:0016462;pyrophosphatase activity;1.27302282984952e-19!GO:0016817;hydrolase activity, acting on acid anhydrides;1.48273242243857e-19!GO:0048770;pigment granule;1.71302694820673e-19!GO:0042470;melanosome;1.71302694820673e-19!GO:0044432;endoplasmic reticulum part;2.85300853467459e-19!GO:0017111;nucleoside-triphosphatase activity;1.21774517112937e-18!GO:0031980;mitochondrial lumen;3.57692506371042e-18!GO:0005759;mitochondrial matrix;3.57692506371042e-18!GO:0005746;mitochondrial respiratory chain;7.1127013512117e-18!GO:0022618;protein-RNA complex assembly;1.01715769863938e-17!GO:0005794;Golgi apparatus;1.01715769863938e-17!GO:0044451;nucleoplasm part;1.7065165550841e-17!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;1.77440935027543e-17!GO:0000502;proteasome complex (sensu Eukaryota);1.45152054993949e-16!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);1.71639447150042e-16!GO:0016874;ligase activity;2.27232637098822e-16!GO:0050136;NADH dehydrogenase (quinone) activity;2.8434530651402e-16!GO:0003954;NADH dehydrogenase activity;2.8434530651402e-16!GO:0008137;NADH dehydrogenase (ubiquinone) activity;2.8434530651402e-16!GO:0051186;cofactor metabolic process;3.06823798310709e-16!GO:0006512;ubiquitin cycle;5.07205433945553e-16!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);6.93243189600539e-16!GO:0008135;translation factor activity, nucleic acid binding;1.59761555137919e-15!GO:0043285;biopolymer catabolic process;2.27174703195486e-15!GO:0000166;nucleotide binding;3.1732698704674e-15!GO:0048193;Golgi vesicle transport;4.77532048418734e-15!GO:0051082;unfolded protein binding;6.03099413796605e-15!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;8.41845230443163e-15!GO:0008134;transcription factor binding;8.75366592301794e-15!GO:0044265;cellular macromolecule catabolic process;1.0283338763965e-14!GO:0005761;mitochondrial ribosome;1.02843889515373e-14!GO:0000313;organellar ribosome;1.02843889515373e-14!GO:0005730;nucleolus;1.59953663790213e-14!GO:0051603;proteolysis involved in cellular protein catabolic process;1.63569416870125e-14!GO:0009057;macromolecule catabolic process;1.96526184846868e-14!GO:0042775;organelle ATP synthesis coupled electron transport;2.13703091026053e-14!GO:0042773;ATP synthesis coupled electron transport;2.13703091026053e-14!GO:0016192;vesicle-mediated transport;2.40676141142753e-14!GO:0030163;protein catabolic process;2.69441582223502e-14!GO:0030964;NADH dehydrogenase complex (quinone);2.69441582223502e-14!GO:0045271;respiratory chain complex I;2.69441582223502e-14!GO:0005747;mitochondrial respiratory chain complex I;2.69441582223502e-14!GO:0019941;modification-dependent protein catabolic process;3.0956708875445e-14!GO:0043632;modification-dependent macromolecule catabolic process;3.0956708875445e-14!GO:0044257;cellular protein catabolic process;3.70649577598093e-14!GO:0006511;ubiquitin-dependent protein catabolic process;6.06898122062139e-14!GO:0042175;nuclear envelope-endoplasmic reticulum network;7.87129107758257e-14!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;8.80795718274297e-14!GO:0006605;protein targeting;1.56287969969744e-13!GO:0044248;cellular catabolic process;1.75617675318715e-13!GO:0006259;DNA metabolic process;2.5261462888702e-13!GO:0005789;endoplasmic reticulum membrane;2.73805304111962e-13!GO:0003743;translation initiation factor activity;4.3571858098657e-13!GO:0012501;programmed cell death;1.85710172566487e-12!GO:0006732;coenzyme metabolic process;2.56591915576647e-12!GO:0009055;electron carrier activity;3.77583457676398e-12!GO:0006915;apoptosis;4.28674991808998e-12!GO:0043412;biopolymer modification;4.84471739978771e-12!GO:0005793;ER-Golgi intermediate compartment;6.03436646189258e-12!GO:0006413;translational initiation;1.15272655861097e-11!GO:0000398;nuclear mRNA splicing, via spliceosome;1.43507010060448e-11!GO:0000375;RNA splicing, via transesterification reactions;1.43507010060448e-11!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.43507010060448e-11!GO:0006464;protein modification process;4.09393756850883e-11!GO:0009259;ribonucleotide metabolic process;4.16198140834598e-11!GO:0008219;cell death;5.09975322970453e-11!GO:0016265;death;5.09975322970453e-11!GO:0006163;purine nucleotide metabolic process;1.08595213402083e-10!GO:0009150;purine ribonucleotide metabolic process;1.25312636648249e-10!GO:0003676;nucleic acid binding;1.5879931368841e-10!GO:0048523;negative regulation of cellular process;1.6107254778638e-10!GO:0032553;ribonucleotide binding;1.75647113246813e-10!GO:0032555;purine ribonucleotide binding;1.75647113246813e-10!GO:0017076;purine nucleotide binding;2.0354438653879e-10!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;2.96906784572862e-10!GO:0042254;ribosome biogenesis and assembly;3.5728428984472e-10!GO:0007049;cell cycle;5.60563708696262e-10!GO:0006164;purine nucleotide biosynthetic process;6.91433601202703e-10!GO:0009152;purine ribonucleotide biosynthetic process;7.64636995668995e-10!GO:0003712;transcription cofactor activity;7.84687990410603e-10!GO:0009260;ribonucleotide biosynthetic process;8.9219494820676e-10!GO:0003924;GTPase activity;1.36325472878237e-09!GO:0006446;regulation of translational initiation;1.50878722493394e-09!GO:0009199;ribonucleoside triphosphate metabolic process;1.60149008989719e-09!GO:0019787;small conjugating protein ligase activity;1.87174402305353e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.1142961676125e-09!GO:0008639;small protein conjugating enzyme activity;2.11486018038775e-09!GO:0008565;protein transporter activity;2.35991217595603e-09!GO:0009141;nucleoside triphosphate metabolic process;2.58320126045698e-09!GO:0009205;purine ribonucleoside triphosphate metabolic process;3.1808191209751e-09!GO:0009144;purine nucleoside triphosphate metabolic process;3.1808191209751e-09!GO:0016491;oxidoreductase activity;3.57433521403082e-09!GO:0004842;ubiquitin-protein ligase activity;4.47881525695433e-09!GO:0048519;negative regulation of biological process;4.58046580530608e-09!GO:0009056;catabolic process;4.98938284622327e-09!GO:0016879;ligase activity, forming carbon-nitrogen bonds;6.91488982177932e-09!GO:0009060;aerobic respiration;7.72024390127155e-09!GO:0016604;nuclear body;7.94953443763505e-09!GO:0015986;ATP synthesis coupled proton transport;8.10041055432413e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;8.10041055432413e-09!GO:0016887;ATPase activity;1.02599506269547e-08!GO:0016070;RNA metabolic process;1.12839527368618e-08!GO:0042623;ATPase activity, coupled;1.18263265825351e-08!GO:0043687;post-translational protein modification;1.24723522792521e-08!GO:0046034;ATP metabolic process;1.29438700856477e-08!GO:0016881;acid-amino acid ligase activity;1.30134666274686e-08!GO:0009142;nucleoside triphosphate biosynthetic process;1.4009477798159e-08!GO:0009201;ribonucleoside triphosphate biosynthetic process;1.4009477798159e-08!GO:0043067;regulation of programmed cell death;1.68938912757877e-08!GO:0005788;endoplasmic reticulum lumen;1.91526973715428e-08!GO:0044431;Golgi apparatus part;2.06521673405035e-08!GO:0006913;nucleocytoplasmic transport;2.40193565216107e-08!GO:0006888;ER to Golgi vesicle-mediated transport;2.45261200353664e-08!GO:0019829;cation-transporting ATPase activity;2.55878579707389e-08!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;2.70779696574941e-08!GO:0042981;regulation of apoptosis;2.71314670288986e-08!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;2.74892016078947e-08!GO:0009145;purine nucleoside triphosphate biosynthetic process;2.74892016078947e-08!GO:0045333;cellular respiration;3.12439824144937e-08!GO:0006399;tRNA metabolic process;3.60338020772027e-08!GO:0051246;regulation of protein metabolic process;3.98004334369734e-08!GO:0051169;nuclear transport;4.54308263658918e-08!GO:0030120;vesicle coat;4.68647550985923e-08!GO:0030662;coated vesicle membrane;4.68647550985923e-08!GO:0051188;cofactor biosynthetic process;6.08497178868372e-08!GO:0015078;hydrogen ion transmembrane transporter activity;6.36335199122598e-08!GO:0043069;negative regulation of programmed cell death;7.33432215490546e-08!GO:0005768;endosome;9.48276142727991e-08!GO:0006754;ATP biosynthetic process;9.53161838258065e-08!GO:0006753;nucleoside phosphate metabolic process;9.53161838258065e-08!GO:0005524;ATP binding;1.00881715037706e-07!GO:0043123;positive regulation of I-kappaB kinase/NF-kappaB cascade;1.14244273717009e-07!GO:0048475;coated membrane;1.52086974475148e-07!GO:0030117;membrane coat;1.52086974475148e-07!GO:0043066;negative regulation of apoptosis;1.54578304178387e-07!GO:0005635;nuclear envelope;1.5477664192071e-07!GO:0006461;protein complex assembly;1.66843597633006e-07!GO:0043122;regulation of I-kappaB kinase/NF-kappaB cascade;1.67993058561157e-07!GO:0032559;adenyl ribonucleotide binding;1.7971775677296e-07!GO:0016787;hydrolase activity;1.7971775677296e-07!GO:0006916;anti-apoptosis;2.49071027540672e-07!GO:0030554;adenyl nucleotide binding;2.49984616232201e-07!GO:0006974;response to DNA damage stimulus;2.64382266207788e-07!GO:0051726;regulation of cell cycle;2.69235470461603e-07!GO:0016607;nuclear speck;2.87105999101408e-07!GO:0030532;small nuclear ribonucleoprotein complex;2.98335440911205e-07!GO:0044453;nuclear membrane part;3.02862498101315e-07!GO:0017038;protein import;3.34362398455758e-07!GO:0000074;regulation of progression through cell cycle;3.99787644194794e-07!GO:0009117;nucleotide metabolic process;4.44375080006991e-07!GO:0005839;proteasome core complex (sensu Eukaryota);4.46900892198005e-07!GO:0031965;nuclear membrane;4.46976145092407e-07!GO:0007249;I-kappaB kinase/NF-kappaB cascade;4.6995752741253e-07!GO:0006099;tricarboxylic acid cycle;5.11585525112763e-07!GO:0046356;acetyl-CoA catabolic process;5.11585525112763e-07!GO:0022402;cell cycle process;5.71619630920869e-07!GO:0016469;proton-transporting two-sector ATPase complex;6.62607649479183e-07!GO:0006325;establishment and/or maintenance of chromatin architecture;7.09972253437986e-07!GO:0007005;mitochondrion organization and biogenesis;8.23964781879291e-07!GO:0005773;vacuole;1.07248646495124e-06!GO:0008026;ATP-dependent helicase activity;1.15646586333725e-06!GO:0006364;rRNA processing;1.17728562267811e-06!GO:0000139;Golgi membrane;1.2652977144886e-06!GO:0006084;acetyl-CoA metabolic process;1.2652977144886e-06!GO:0031988;membrane-bound vesicle;1.29661862608474e-06!GO:0051187;cofactor catabolic process;1.31337995051161e-06!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;1.33239694934209e-06!GO:0004812;aminoacyl-tRNA ligase activity;1.33239694934209e-06!GO:0016875;ligase activity, forming carbon-oxygen bonds;1.33239694934209e-06!GO:0016072;rRNA metabolic process;1.35853921684081e-06!GO:0065004;protein-DNA complex assembly;1.56794584375347e-06!GO:0045259;proton-transporting ATP synthase complex;1.69862107062237e-06!GO:0006323;DNA packaging;1.86656824870449e-06!GO:0048522;positive regulation of cellular process;1.98914109457831e-06!GO:0043038;amino acid activation;2.00250601419418e-06!GO:0006418;tRNA aminoacylation for protein translation;2.00250601419418e-06!GO:0043039;tRNA aminoacylation;2.00250601419418e-06!GO:0016023;cytoplasmic membrane-bound vesicle;2.03439156905141e-06!GO:0006091;generation of precursor metabolites and energy;2.17025266223735e-06!GO:0006752;group transfer coenzyme metabolic process;2.70219452603782e-06!GO:0009109;coenzyme catabolic process;3.09164473096352e-06!GO:0031252;leading edge;3.60077271843053e-06!GO:0006366;transcription from RNA polymerase II promoter;3.75871738950092e-06!GO:0005798;Golgi-associated vesicle;4.02500946442125e-06!GO:0004298;threonine endopeptidase activity;4.25050985655399e-06!GO:0004386;helicase activity;4.28569469802639e-06!GO:0032446;protein modification by small protein conjugation;4.44776777758262e-06!GO:0065002;intracellular protein transport across a membrane;4.60122860401707e-06!GO:0005770;late endosome;4.94950275861417e-06!GO:0044440;endosomal part;5.08406337559917e-06!GO:0010008;endosome membrane;5.08406337559917e-06!GO:0005762;mitochondrial large ribosomal subunit;5.15204119490302e-06!GO:0000315;organellar large ribosomal subunit;5.15204119490302e-06!GO:0009108;coenzyme biosynthetic process;5.21713409926663e-06!GO:0016853;isomerase activity;5.34072555286076e-06!GO:0006333;chromatin assembly or disassembly;5.65333388159117e-06!GO:0015077;monovalent inorganic cation transmembrane transporter activity;5.65648929690402e-06!GO:0005667;transcription factor complex;5.76921607401671e-06!GO:0005525;GTP binding;7.41982001896414e-06!GO:0016567;protein ubiquitination;7.82529323715854e-06!GO:0005905;coated pit;8.72977804968225e-06!GO:0005643;nuclear pore;8.93268914940722e-06!GO:0000278;mitotic cell cycle;8.94552885440932e-06!GO:0030036;actin cytoskeleton organization and biogenesis;9.25419648177958e-06!GO:0006281;DNA repair;9.41584360043069e-06!GO:0031982;vesicle;1.09569137339898e-05!GO:0051276;chromosome organization and biogenesis;1.17913168378056e-05!GO:0000245;spliceosome assembly;1.20943869649312e-05!GO:0016859;cis-trans isomerase activity;1.41726064286648e-05!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;1.42289819759739e-05!GO:0006613;cotranslational protein targeting to membrane;1.51763099902582e-05!GO:0000323;lytic vacuole;1.5547338395751e-05!GO:0005764;lysosome;1.5547338395751e-05!GO:0050794;regulation of cellular process;1.5839167881991e-05!GO:0051789;response to protein stimulus;1.5839167881991e-05!GO:0006986;response to unfolded protein;1.5839167881991e-05!GO:0031410;cytoplasmic vesicle;1.8309280421257e-05!GO:0003713;transcription coactivator activity;2.07037744151375e-05!GO:0045786;negative regulation of progression through cell cycle;2.07412056997603e-05!GO:0000151;ubiquitin ligase complex;2.22411419628979e-05!GO:0045454;cell redox homeostasis;2.45060209142882e-05!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;2.61755450717225e-05!GO:0007243;protein kinase cascade;2.78644959245668e-05!GO:0015980;energy derivation by oxidation of organic compounds;3.36556165170011e-05!GO:0009719;response to endogenous stimulus;3.84202397826118e-05!GO:0019843;rRNA binding;4.00093459672183e-05!GO:0030867;rough endoplasmic reticulum membrane;4.08019374069653e-05!GO:0046930;pore complex;4.12056731893237e-05!GO:0008654;phospholipid biosynthetic process;4.2925613021741e-05!GO:0000785;chromatin;4.52956625591039e-05!GO:0003714;transcription corepressor activity;5.52822292971027e-05!GO:0006334;nucleosome assembly;5.66281988728334e-05!GO:0032561;guanyl ribonucleotide binding;7.11912390185154e-05!GO:0019001;guanyl nucleotide binding;7.11912390185154e-05!GO:0016563;transcription activator activity;8.19390253329616e-05!GO:0016564;transcription repressor activity;9.26381095245478e-05!GO:0030029;actin filament-based process;9.46019157070891e-05!GO:0051170;nuclear import;9.46019157070891e-05!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.000100669079678167!GO:0006793;phosphorus metabolic process;0.000101272178790521!GO:0006796;phosphate metabolic process;0.000101272178790521!GO:0030133;transport vesicle;0.000106098476056366!GO:0033116;ER-Golgi intermediate compartment membrane;0.000106253088590218!GO:0031324;negative regulation of cellular metabolic process;0.000107241979293775!GO:0003697;single-stranded DNA binding;0.000110547884682347!GO:0050657;nucleic acid transport;0.000114303852832366!GO:0051236;establishment of RNA localization;0.000114303852832366!GO:0050658;RNA transport;0.000114303852832366!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;0.000116862284397099!GO:0006403;RNA localization;0.000119856584887838!GO:0043623;cellular protein complex assembly;0.000131527720665512!GO:0019867;outer membrane;0.000131798611139135!GO:0008361;regulation of cell size;0.000139476843141663!GO:0031968;organelle outer membrane;0.000144125192438054!GO:0006606;protein import into nucleus;0.000145116055734516!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;0.000155418981233177!GO:0015399;primary active transmembrane transporter activity;0.000155418981233177!GO:0016049;cell growth;0.000160735406311905!GO:0005852;eukaryotic translation initiation factor 3 complex;0.000162927494790373!GO:0031497;chromatin assembly;0.000164850659294651!GO:0043021;ribonucleoprotein binding;0.00019127895929607!GO:0000314;organellar small ribosomal subunit;0.000196626539655494!GO:0005763;mitochondrial small ribosomal subunit;0.000196626539655494!GO:0003724;RNA helicase activity;0.000225376549462407!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.000246757584654711!GO:0005769;early endosome;0.00025120460654525!GO:0005048;signal sequence binding;0.00025120460654525!GO:0043566;structure-specific DNA binding;0.00026101913254833!GO:0001558;regulation of cell growth;0.000264630752587495!GO:0016044;membrane organization and biogenesis;0.000265869568872398!GO:0016740;transferase activity;0.000268608057338369!GO:0016310;phosphorylation;0.000284941673327898!GO:0048518;positive regulation of biological process;0.00029021500770654!GO:0005885;Arp2/3 protein complex;0.000300210970832916!GO:0005694;chromosome;0.000303770337154266!GO:0008092;cytoskeletal protein binding;0.000307763939592783!GO:0051427;hormone receptor binding;0.000316398712354729!GO:0008250;oligosaccharyl transferase complex;0.000328844742335766!GO:0004576;oligosaccharyl transferase activity;0.000348390569548015!GO:0006612;protein targeting to membrane;0.000372827817266358!GO:0006414;translational elongation;0.000375659607314193!GO:0004579;dolichyl-diphosphooligosaccharide-protein glycotransferase activity;0.000444097648846829!GO:0019899;enzyme binding;0.000472307066828278!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000506785494382799!GO:0016779;nucleotidyltransferase activity;0.00053464549038083!GO:0009892;negative regulation of metabolic process;0.00054450085384046!GO:0009165;nucleotide biosynthetic process;0.000552468841193212!GO:0043284;biopolymer biosynthetic process;0.000553482885899197!GO:0005741;mitochondrial outer membrane;0.000558112073110347!GO:0031072;heat shock protein binding;0.000601810626850907!GO:0044427;chromosomal part;0.000623182393757642!GO:0035257;nuclear hormone receptor binding;0.000641727672524245!GO:0044262;cellular carbohydrate metabolic process;0.00071354537173467!GO:0003899;DNA-directed RNA polymerase activity;0.00071354537173467!GO:0051920;peroxiredoxin activity;0.000744149009854276!GO:0065009;regulation of a molecular function;0.000793397328595839!GO:0030663;COPI coated vesicle membrane;0.000812541824139738!GO:0030126;COPI vesicle coat;0.000812541824139738!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.000830530745861481!GO:0007010;cytoskeleton organization and biogenesis;0.000881915613235372!GO:0050789;regulation of biological process;0.000925554911708681!GO:0015630;microtubule cytoskeleton;0.000945293438586967!GO:0046474;glycerophospholipid biosynthetic process;0.00094722306082021!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000953232066625459!GO:0009967;positive regulation of signal transduction;0.000962107739218848!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.00101852576553571!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00102063960090322!GO:0018196;peptidyl-asparagine modification;0.00108961651537254!GO:0018279;protein amino acid N-linked glycosylation via asparagine;0.00108961651537254!GO:0016568;chromatin modification;0.0011025499295681!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0011927608694351!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0011927608694351!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0011927608694351!GO:0051028;mRNA transport;0.00121647119335318!GO:0006260;DNA replication;0.00134260376064052!GO:0043681;protein import into mitochondrion;0.00156685280908961!GO:0008047;enzyme activator activity;0.00162807741756689!GO:0030176;integral to endoplasmic reticulum membrane;0.00168315358794601!GO:0030137;COPI-coated vesicle;0.00190822321520952!GO:0016765;transferase activity, transferring alkyl or aryl (other than methyl) groups;0.001965259913476!GO:0006383;transcription from RNA polymerase III promoter;0.00200211741171516!GO:0016281;eukaryotic translation initiation factor 4F complex;0.0021345321550773!GO:0043492;ATPase activity, coupled to movement of substances;0.00214200138023953!GO:0030658;transport vesicle membrane;0.00221374512530705!GO:0006891;intra-Golgi vesicle-mediated transport;0.00229972058637167!GO:0045934;negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00230197410128377!GO:0006626;protein targeting to mitochondrion;0.00234563762390329!GO:0051301;cell division;0.00234899842528102!GO:0048500;signal recognition particle;0.00243383501930064!GO:0004177;aminopeptidase activity;0.00246955814177058!GO:0030118;clathrin coat;0.00250790468622894!GO:0003729;mRNA binding;0.0025171291621194!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;0.00257961731423173!GO:0007264;small GTPase mediated signal transduction;0.0025961659578844!GO:0000087;M phase of mitotic cell cycle;0.00270461973903887!GO:0022890;inorganic cation transmembrane transporter activity;0.00274590333943425!GO:0046489;phosphoinositide biosynthetic process;0.00293264226899177!GO:0000307;cyclin-dependent protein kinase holoenzyme complex;0.00294500435434821!GO:0008186;RNA-dependent ATPase activity;0.00295973972493221!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00303924408567044!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00303924408567044!GO:0006839;mitochondrial transport;0.00311279641565074!GO:0016481;negative regulation of transcription;0.00320124506689584!GO:0006082;organic acid metabolic process;0.0032526936263813!GO:0007067;mitosis;0.0033253271181446!GO:0019752;carboxylic acid metabolic process;0.00354319071326378!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.00362463576709701!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.00373652249177942!GO:0005813;centrosome;0.00376176416432175!GO:0030041;actin filament polymerization;0.00377234161657836!GO:0008243;plasminogen activator activity;0.00379007664532566!GO:0051168;nuclear export;0.00379234199418104!GO:0048468;cell development;0.00379234199418104!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00385854501828246!GO:0030880;RNA polymerase complex;0.00391877823163842!GO:0030132;clathrin coat of coated pit;0.00398073846912352!GO:0016667;oxidoreductase activity, acting on sulfur group of donors;0.00400334120775575!GO:0045935;positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;0.00404703030210388!GO:0007006;mitochondrial membrane organization and biogenesis;0.00404703030210388!GO:0030027;lamellipodium;0.0042630902229454!GO:0007040;lysosome organization and biogenesis;0.00446813105776652!GO:0008180;signalosome;0.0044907013397735!GO:0051087;chaperone binding;0.0044907013397735!GO:0015992;proton transport;0.00449713815444479!GO:0006818;hydrogen transport;0.00454716180811654!GO:0046467;membrane lipid biosynthetic process;0.00473358290806134!GO:0048487;beta-tubulin binding;0.0047566220838581!GO:0000786;nucleosome;0.00476062236512284!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.00477367580686255!GO:0045047;protein targeting to ER;0.00477367580686255!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.00477367580686255!GO:0015002;heme-copper terminal oxidase activity;0.00477367580686255!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.00477367580686255!GO:0004129;cytochrome-c oxidase activity;0.00477367580686255!GO:0008610;lipid biosynthetic process;0.00486396564472023!GO:0045941;positive regulation of transcription;0.00489518047245453!GO:0006950;response to stress;0.00529374263457192!GO:0045045;secretory pathway;0.00541892102743578!GO:0045893;positive regulation of transcription, DNA-dependent;0.00545438553199421!GO:0005791;rough endoplasmic reticulum;0.00560176508091737!GO:0030134;ER to Golgi transport vesicle;0.00562760532881907!GO:0040008;regulation of growth;0.00573172186481691!GO:0008139;nuclear localization sequence binding;0.00588361670715149!GO:0030660;Golgi-associated vesicle membrane;0.00590439287674383!GO:0042802;identical protein binding;0.00606442033194712!GO:0016272;prefoldin complex;0.00609483296318991!GO:0003746;translation elongation factor activity;0.0062145279944325!GO:0006650;glycerophospholipid metabolic process;0.00622178331322417!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.00628171563937108!GO:0008033;tRNA processing;0.00629417642082244!GO:0048471;perinuclear region of cytoplasm;0.00630139291999241!GO:0016126;sterol biosynthetic process;0.00639766022233067!GO:0008312;7S RNA binding;0.00669386801510083!GO:0046519;sphingoid metabolic process;0.00680923126724733!GO:0044452;nucleolar part;0.00692599580972079!GO:0008154;actin polymerization and/or depolymerization;0.00698234311813409!GO:0005815;microtubule organizing center;0.00700051140058769!GO:0046483;heterocycle metabolic process;0.00702247396120807!GO:0006740;NADPH regeneration;0.00702247396120807!GO:0006098;pentose-phosphate shunt;0.00702247396120807!GO:0030127;COPII vesicle coat;0.00702247396120807!GO:0012507;ER to Golgi transport vesicle membrane;0.00702247396120807!GO:0006778;porphyrin metabolic process;0.00702247396120807!GO:0033013;tetrapyrrole metabolic process;0.00702247396120807!GO:0016862;intramolecular oxidoreductase activity, interconverting keto- and enol-groups;0.00702247396120807!GO:0008632;apoptotic program;0.00710822793050897!GO:0004004;ATP-dependent RNA helicase activity;0.00714718208146667!GO:0017166;vinculin binding;0.00748864867125574!GO:0030659;cytoplasmic vesicle membrane;0.00757874893369232!GO:0007050;cell cycle arrest;0.00760218431682372!GO:0016363;nuclear matrix;0.00766335456183068!GO:0006509;membrane protein ectodomain proteolysis;0.00767231550214716!GO:0033619;membrane protein proteolysis;0.00767231550214716!GO:0006118;electron transport;0.00789498271405866!GO:0016197;endosome transport;0.00792025054894534!GO:0055029;nuclear DNA-directed RNA polymerase complex;0.00817146947324876!GO:0000428;DNA-directed RNA polymerase complex;0.00817146947324876!GO:0001726;ruffle;0.00887215939569434!GO:0005869;dynactin complex;0.00887595054514527!GO:0006357;regulation of transcription from RNA polymerase II promoter;0.00893028132580564!GO:0007033;vacuole organization and biogenesis;0.009005453976807!GO:0035258;steroid hormone receptor binding;0.00932952505872268!GO:0030521;androgen receptor signaling pathway;0.00943083741917584!GO:0042168;heme metabolic process;0.00956868680236355!GO:0006595;polyamine metabolic process;0.00982562862306771!GO:0006897;endocytosis;0.010042710766331!GO:0010324;membrane invagination;0.010042710766331!GO:0005862;muscle thin filament tropomyosin;0.0107366461497559!GO:0005684;U2-dependent spliceosome;0.0107366461497559!GO:0016627;oxidoreductase activity, acting on the CH-CH group of donors;0.0110875109675762!GO:0051329;interphase of mitotic cell cycle;0.0116721892147734!GO:0051101;regulation of DNA binding;0.0116848386339487!GO:0006497;protein amino acid lipidation;0.0122590928362587!GO:0033673;negative regulation of kinase activity;0.0122830667148628!GO:0006469;negative regulation of protein kinase activity;0.0122830667148628!GO:0003711;transcription elongation regulator activity;0.0127878832868324!GO:0030865;cortical cytoskeleton organization and biogenesis;0.0130780606273131!GO:0030125;clathrin vesicle coat;0.0132672456717138!GO:0030665;clathrin coated vesicle membrane;0.0132672456717138!GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors;0.0132672456717138!GO:0015631;tubulin binding;0.0133728733471959!GO:0050811;GABA receptor binding;0.0135310991677341!GO:0045792;negative regulation of cell size;0.0139396614358984!GO:0030308;negative regulation of cell growth;0.0144682292891954!GO:0022403;cell cycle phase;0.0145319909964118!GO:0051539;4 iron, 4 sulfur cluster binding;0.0146231218387324!GO:0006672;ceramide metabolic process;0.0149062615870681!GO:0051348;negative regulation of transferase activity;0.0151956886797608!GO:0051540;metal cluster binding;0.0151956886797608!GO:0051536;iron-sulfur cluster binding;0.0151956886797608!GO:0030833;regulation of actin filament polymerization;0.0152237378750432!GO:0043022;ribosome binding;0.0152670029623981!GO:0006892;post-Golgi vesicle-mediated transport;0.0154881151794585!GO:0048144;fibroblast proliferation;0.0157860678002528!GO:0048145;regulation of fibroblast proliferation;0.0157860678002528!GO:0044433;cytoplasmic vesicle part;0.0158126141799038!GO:0051252;regulation of RNA metabolic process;0.0162666536170837!GO:0007034;vacuolar transport;0.0162838756425249!GO:0012506;vesicle membrane;0.0171211954594034!GO:0030119;AP-type membrane coat adaptor complex;0.0180249182120396!GO:0005832;chaperonin-containing T-complex;0.0183272345517353!GO:0006779;porphyrin biosynthetic process;0.018881190183611!GO:0033014;tetrapyrrole biosynthetic process;0.018881190183611!GO:0046426;negative regulation of JAK-STAT cascade;0.0188812811182347!GO:0031529;ruffle organization and biogenesis;0.0190151369456371!GO:0043068;positive regulation of programmed cell death;0.0197709372966457!GO:0031902;late endosome membrane;0.0204926217265134!GO:0043065;positive regulation of apoptosis;0.0204926217265134!GO:0000059;protein import into nucleus, docking;0.0205724529573781!GO:0006695;cholesterol biosynthetic process;0.0206825339530893!GO:0006979;response to oxidative stress;0.0207029871718033!GO:0007021;tubulin folding;0.0213098010786449!GO:0006352;transcription initiation;0.0213854337750831!GO:0051287;NAD binding;0.0219655461337476!GO:0051128;regulation of cellular component organization and biogenesis;0.0220302401556546!GO:0006520;amino acid metabolic process;0.022263523969032!GO:0019205;nucleobase, nucleoside, nucleotide kinase activity;0.0223324570572165!GO:0016780;phosphotransferase activity, for other substituted phosphate groups;0.0223361872249694!GO:0043161;proteasomal ubiquitin-dependent protein catabolic process;0.0225459631298544!GO:0050681;androgen receptor binding;0.023144394336029!GO:0051098;regulation of binding;0.023410052693632!GO:0000082;G1/S transition of mitotic cell cycle;0.0238852471875041!GO:0050662;coenzyme binding;0.0238852471875041!GO:0050790;regulation of catalytic activity;0.0239447070664241!GO:0003756;protein disulfide isomerase activity;0.0239856365236902!GO:0016864;intramolecular oxidoreductase activity, transposing S-S bonds;0.0239856365236902!GO:0005665;DNA-directed RNA polymerase II, core complex;0.0239856365236902!GO:0000049;tRNA binding;0.0240167952214128!GO:0006402;mRNA catabolic process;0.0252344805627285!GO:0006783;heme biosynthetic process;0.0254387301644343!GO:0000209;protein polyubiquitination;0.0255199015813574!GO:0006506;GPI anchor biosynthetic process;0.0255994408005739!GO:0003779;actin binding;0.0257615409916157!GO:0000339;RNA cap binding;0.0257615409916157!GO:0048146;positive regulation of fibroblast proliferation;0.0259790139049527!GO:0003690;double-stranded DNA binding;0.0263635231500035!GO:0022408;negative regulation of cell-cell adhesion;0.0273728444689385!GO:0030384;phosphoinositide metabolic process;0.0277610901568593!GO:0031901;early endosome membrane;0.0294678543851325!GO:0042158;lipoprotein biosynthetic process;0.029647651281996!GO:0051271;negative regulation of cell motility;0.0299816698082262!GO:0031625;ubiquitin protein ligase binding;0.0304107665605067!GO:0030032;lamellipodium biogenesis;0.0304509256550115!GO:0008637;apoptotic mitochondrial changes;0.0312369832599205!GO:0045936;negative regulation of phosphate metabolic process;0.0312422487644603!GO:0006518;peptide metabolic process;0.0313915068797107!GO:0032984;macromolecular complex disassembly;0.0314732174469286!GO:0030131;clathrin adaptor complex;0.031937747766848!GO:0032940;secretion by cell;0.0320979613202452!GO:0001952;regulation of cell-matrix adhesion;0.0322357141361361!GO:0031418;L-ascorbic acid binding;0.0323860899827092!GO:0005096;GTPase activator activity;0.0329400395507934!GO:0008538;proteasome activator activity;0.0329886985926425!GO:0006378;mRNA polyadenylation;0.0332095838969446!GO:0008383;manganese superoxide dismutase activity;0.0335765334878733!GO:0001315;age-dependent response to reactive oxygen species;0.0335765334878733!GO:0035035;histone acetyltransferase binding;0.0347871728119894!GO:0006007;glucose catabolic process;0.0348451689300996!GO:0006401;RNA catabolic process;0.0348786639660672!GO:0006354;RNA elongation;0.035136510162489!GO:0031371;ubiquitin conjugating enzyme complex;0.035479213420571!GO:0065007;biological regulation;0.0357026361998412!GO:0017015;regulation of transforming growth factor beta receptor signaling pathway;0.0360905006534304!GO:0031124;mRNA 3'-end processing;0.0364096046234551!GO:0008064;regulation of actin polymerization and/or depolymerization;0.0365332119492736!GO:0005801;cis-Golgi network;0.0365902717926304!GO:0006739;NADP metabolic process;0.0370027220245064!GO:0006505;GPI anchor metabolic process;0.0371194542068421!GO:0001953;negative regulation of cell-matrix adhesion;0.0372353621591772!GO:0006984;ER-nuclear signaling pathway;0.0373807647918593!GO:0004287;prolyl oligopeptidase activity;0.0381563203538196!GO:0008320;protein transmembrane transporter activity;0.0382857389774819!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0382968424640739!GO:0000096;sulfur amino acid metabolic process;0.0383544575240243!GO:0006611;protein export from nucleus;0.0384681351172843!GO:0030518;steroid hormone receptor signaling pathway;0.0384681351172843!GO:0032981;mitochondrial respiratory chain complex I assembly;0.0384681351172843!GO:0010257;NADH dehydrogenase complex assembly;0.0384681351172843!GO:0033108;mitochondrial respiratory chain complex assembly;0.0384681351172843!GO:0051493;regulation of cytoskeleton organization and biogenesis;0.0384681351172843!GO:0033043;regulation of organelle organization and biogenesis;0.0384681351172843!GO:0022884;macromolecule transmembrane transporter activity;0.0388375393809707!GO:0015450;P-P-bond-hydrolysis-driven protein transmembrane transporter activity;0.0388375393809707!GO:0016408;C-acyltransferase activity;0.0389803200896209!GO:0045926;negative regulation of growth;0.0391124668183122!GO:0043488;regulation of mRNA stability;0.039210289279534!GO:0043487;regulation of RNA stability;0.039210289279534!GO:0045892;negative regulation of transcription, DNA-dependent;0.0395500928588426!GO:0043433;negative regulation of transcription factor activity;0.0397285488851635!GO:0005774;vacuolar membrane;0.0398324744491681!GO:0006807;nitrogen compound metabolic process;0.0401613667098423!GO:0051045;negative regulation of membrane protein ectodomain proteolysis;0.0401613667098423!GO:0051043;regulation of membrane protein ectodomain proteolysis;0.0401613667098423!GO:0008234;cysteine-type peptidase activity;0.0404210423044835!GO:0008022;protein C-terminus binding;0.0406999870134211!GO:0042532;negative regulation of tyrosine phosphorylation of STAT protein;0.0406999870134211!GO:0042518;negative regulation of tyrosine phosphorylation of Stat3 protein;0.0406999870134211!GO:0050732;negative regulation of peptidyl-tyrosine phosphorylation;0.0406999870134211!GO:0031301;integral to organelle membrane;0.0416673709665482!GO:0030433;ER-associated protein catabolic process;0.0422827754524333!GO:0006515;misfolded or incompletely synthesized protein catabolic process;0.0422827754524333!GO:0006417;regulation of translation;0.0422827754524333!GO:0003684;damaged DNA binding;0.0425300642722481!GO:0030911;TPR domain binding;0.0438706336137828!GO:0005092;GDP-dissociation inhibitor activity;0.0441543565691722!GO:0030508;thiol-disulfide exchange intermediate activity;0.0441543565691722!GO:0006368;RNA elongation from RNA polymerase II promoter;0.0463333460935575!GO:0030031;cell projection biogenesis;0.0470356366962856!GO:0051325;interphase;0.0474674722372074!GO:0006643;membrane lipid metabolic process;0.04753942092868!GO:0008475;procollagen-lysine 5-dioxygenase activity;0.0476100266893066!GO:0000079;regulation of cyclin-dependent protein kinase activity;0.0481907771839643!GO:0006376;mRNA splice site selection;0.0481907771839643!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0481907771839643!GO:0001527;microfibril;0.0483989686138549!GO:0046822;regulation of nucleocytoplasmic transport;0.0486860626632424!GO:0009893;positive regulation of metabolic process;0.0489624728178336!GO:0008147;structural constituent of bone;0.0493555160437478!GO:0043071;positive regulation of non-apoptotic programmed cell death;0.0494463799308334!GO:0008283;cell proliferation;0.0495307736492834 | |||
|sample_id=12750 | |sample_id=12750 | ||
|sample_note= | |sample_note= | ||
Line 74: | Line 100: | ||
|sample_strain= | |sample_strain= | ||
|sample_tissue=aorta | |sample_tissue=aorta | ||
|time= 00hr00min | |||
|timecourse=AoSMC_response_to_IL1b | |||
|top_motifs=ALX4:1.97343153572;NKX3-1:1.80310768102;FOXL1:1.79220108379;NKX2-2,8:1.77148191571;ONECUT1,2:1.67250043251;UFEwm:1.54823236717;EVI1:1.41258382106;TP53:1.37975114278;ZNF384:1.23417189836;NFE2L1:1.21222902553;GZF1:1.13163394631;ZBTB6:1.10496524936;ZNF238:1.09024239911;HOX{A4,D4}:0.972350563512;EN1,2:0.961749193671;RXR{A,B,G}:0.941339115504;HMGA1,2:0.932226711439;GATA4:0.931971022646;GCM1,2:0.927249550195;FOXD3:0.896603628663;MYBL2:0.890216543357;DBP:0.863753718584;NKX3-2:0.828462776795;KLF4:0.787476176258;HSF1,2:0.773593215669;NFATC1..3:0.76622925823;SRF:0.743699417727;XBP1:0.730510681983;TEAD1:0.69962397729;POU6F1:0.692551044565;TAL1_TCF{3,4,12}:0.673735898004;PPARG:0.670607637853;HOX{A5,B5}:0.665393347892;TFAP4:0.664443068678;ZIC1..3:0.662328409095;FOXQ1:0.659003538346;FOX{I1,J2}:0.65506712253;TLX1..3_NFIC{dimer}:0.644572162261;TEF:0.639447301618;POU1F1:0.613776605689;PAX4:0.578796482704;PAX8:0.573463404395;TFCP2:0.568593082746;HES1:0.563155798519;FOXM1:0.550043085064;NKX2-1,4:0.519840206978;CDX1,2,4:0.501894473573;GTF2A1,2:0.496779285936;GFI1B:0.485673733514;TBP:0.455993850917;NR3C1:0.404113502233;AIRE:0.403141526619;PAX1,9:0.401914377484;NKX6-1,2:0.399199253269;EBF1:0.379140330718;PRDM1:0.378708579655;HBP1_HMGB_SSRP1_UBTF:0.377316138641;NANOG{mouse}:0.376872826068;TLX2:0.351307344482;BPTF:0.331106836545;NFE2L2:0.322383653087;GLI1..3:0.319827135361;HMX1:0.318482727608;HAND1,2:0.312523466988;LHX3,4:0.285388421398;ATF6:0.28219498127;CDC5L:0.282094944389;POU3F1..4:0.267133986539;ADNP_IRX_SIX_ZHX:0.26671176162;GTF2I:0.23567047431;REST:0.232333368569;ALX1:0.216527443431;BACH2:0.196532336552;ZBTB16:0.18521573061;MAFB:0.176162494136;CRX:0.158671261781;AR:0.129291982505;NFIX:0.123711812745;HLF:0.106987836918;SOX2:0.0926939237935;FOS_FOS{B,L1}_JUN{B,D}:0.0896215865611;bHLH_family:0.0642266028169;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.0582870907977;SOX17:0.0201764358405;NFKB1_REL_RELA:0.0197367240793;SPZ1:0.0114850147175;FOXP3:-0.0105952642625;MZF1:-0.0134068473159;HNF1A:-0.0204173597496;TBX4,5:-0.0463291956431;TFAP2B:-0.0690723475241;ARID5B:-0.102099054518;XCPE1{core}:-0.140020170044;PATZ1:-0.152651171719;MTE{core}:-0.153070122222;SMAD1..7,9:-0.160284467974;ESR1:-0.162669471771;STAT2,4,6:-0.173860924064;JUN:-0.177414253228;FOX{D1,D2}:-0.191840930637;PAX5:-0.200806049248;FOSL2:-0.202325647055;IKZF2:-0.204935379543;MEF2{A,B,C,D}:-0.216712277946;SOX{8,9,10}:-0.216760752579;RUNX1..3:-0.221851367593;MYFfamily:-0.22905762452;PITX1..3:-0.236249410496;NR6A1:-0.237407459497;LEF1_TCF7_TCF7L1,2:-0.238947919718;IKZF1:-0.240392771564;ELK1,4_GABP{A,B1}:-0.241019730277;SOX5:-0.24449936161;HIC1:-0.2456625474;NFE2:-0.25244767731;PAX6:-0.257885442917;TFAP2{A,C}:-0.262302909665;OCT4_SOX2{dimer}:-0.275466709124;PBX1:-0.283731100305;STAT5{A,B}:-0.286037756447;POU2F1..3:-0.28727156302;PRRX1,2:-0.29394301536;IRF1,2:-0.29418471669;NFIL3:-0.299367321266;MAZ:-0.303544007645;ZFP161:-0.306868517051;ELF1,2,4:-0.307521602735;RXRA_VDR{dimer}:-0.31739676182;MED-1{core}:-0.320812191556;DMAP1_NCOR{1,2}_SMARC:-0.326336684479;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.353926179563;NHLH1,2:-0.355188117145;ETS1,2:-0.365995188669;SPI1:-0.371858132711;MTF1:-0.38026998986;YY1:-0.381627087499;HOXA9_MEIS1:-0.381673428938;HNF4A_NR2F1,2:-0.385635676954;ZNF148:-0.407972651281;FOXP1:-0.410865910628;HOX{A6,A7,B6,B7}:-0.426471518217;LMO2:-0.429147822677;AHR_ARNT_ARNT2:-0.436255799054;RREB1:-0.458757251345;EGR1..3:-0.470845870416;CEBPA,B_DDIT3:-0.471193494694;ESRRA:-0.47233840059;HIF1A:-0.485123349903;NKX2-3_NKX2-5:-0.485799803385;ZNF143:-0.490900197989;SPIB:-0.492144319938;MYB:-0.492629068138;TFDP1:-0.502104135496;PAX2:-0.514040749917;RFX1:-0.538818096013;NRF1:-0.552215255124;ZEB1:-0.553223761786;POU5F1:-0.557032322715;TOPORS:-0.607535810852;SNAI1..3:-0.610833799439;SP1:-0.642536919165;ATF5_CREB3:-0.644206829423;FOX{F1,F2,J1}:-0.649962964987;GFI1:-0.651300699683;SREBF1,2:-0.671418191947;TGIF1:-0.678574685136;ATF2:-0.681019690716;CREB1:-0.687681342176;GATA6:-0.74736942979;FOXO1,3,4:-0.753493990707;CUX2:-0.762240005097;ZNF423:-0.770189283317;STAT1,3:-0.775472508968;T:-0.781951239471;NR1H4:-0.811998774872;E2F1..5:-0.879782672633;IRF7:-0.913604043717;PAX3,7:-0.925656798821;MYOD1:-0.990834272408;PDX1:-1.01728390555;NANOG:-1.1155455982;NR5A1,2:-1.12997531591;ATF4:-1.13349538463;FOXN1:-1.16033302566;RFX2..5_RFXANK_RFXAP:-1.16703634361;VSX1,2:-1.20164931238;RORA:-1.22287728534;BREu{core}:-1.23742022749;NFY{A,B,C}:-1.28428412346;FOXA2:-1.30410661774;EP300:-1.33205537494;RBPJ:-1.50009942631 | |top_motifs=ALX4:1.97343153572;NKX3-1:1.80310768102;FOXL1:1.79220108379;NKX2-2,8:1.77148191571;ONECUT1,2:1.67250043251;UFEwm:1.54823236717;EVI1:1.41258382106;TP53:1.37975114278;ZNF384:1.23417189836;NFE2L1:1.21222902553;GZF1:1.13163394631;ZBTB6:1.10496524936;ZNF238:1.09024239911;HOX{A4,D4}:0.972350563512;EN1,2:0.961749193671;RXR{A,B,G}:0.941339115504;HMGA1,2:0.932226711439;GATA4:0.931971022646;GCM1,2:0.927249550195;FOXD3:0.896603628663;MYBL2:0.890216543357;DBP:0.863753718584;NKX3-2:0.828462776795;KLF4:0.787476176258;HSF1,2:0.773593215669;NFATC1..3:0.76622925823;SRF:0.743699417727;XBP1:0.730510681983;TEAD1:0.69962397729;POU6F1:0.692551044565;TAL1_TCF{3,4,12}:0.673735898004;PPARG:0.670607637853;HOX{A5,B5}:0.665393347892;TFAP4:0.664443068678;ZIC1..3:0.662328409095;FOXQ1:0.659003538346;FOX{I1,J2}:0.65506712253;TLX1..3_NFIC{dimer}:0.644572162261;TEF:0.639447301618;POU1F1:0.613776605689;PAX4:0.578796482704;PAX8:0.573463404395;TFCP2:0.568593082746;HES1:0.563155798519;FOXM1:0.550043085064;NKX2-1,4:0.519840206978;CDX1,2,4:0.501894473573;GTF2A1,2:0.496779285936;GFI1B:0.485673733514;TBP:0.455993850917;NR3C1:0.404113502233;AIRE:0.403141526619;PAX1,9:0.401914377484;NKX6-1,2:0.399199253269;EBF1:0.379140330718;PRDM1:0.378708579655;HBP1_HMGB_SSRP1_UBTF:0.377316138641;NANOG{mouse}:0.376872826068;TLX2:0.351307344482;BPTF:0.331106836545;NFE2L2:0.322383653087;GLI1..3:0.319827135361;HMX1:0.318482727608;HAND1,2:0.312523466988;LHX3,4:0.285388421398;ATF6:0.28219498127;CDC5L:0.282094944389;POU3F1..4:0.267133986539;ADNP_IRX_SIX_ZHX:0.26671176162;GTF2I:0.23567047431;REST:0.232333368569;ALX1:0.216527443431;BACH2:0.196532336552;ZBTB16:0.18521573061;MAFB:0.176162494136;CRX:0.158671261781;AR:0.129291982505;NFIX:0.123711812745;HLF:0.106987836918;SOX2:0.0926939237935;FOS_FOS{B,L1}_JUN{B,D}:0.0896215865611;bHLH_family:0.0642266028169;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:0.0582870907977;SOX17:0.0201764358405;NFKB1_REL_RELA:0.0197367240793;SPZ1:0.0114850147175;FOXP3:-0.0105952642625;MZF1:-0.0134068473159;HNF1A:-0.0204173597496;TBX4,5:-0.0463291956431;TFAP2B:-0.0690723475241;ARID5B:-0.102099054518;XCPE1{core}:-0.140020170044;PATZ1:-0.152651171719;MTE{core}:-0.153070122222;SMAD1..7,9:-0.160284467974;ESR1:-0.162669471771;STAT2,4,6:-0.173860924064;JUN:-0.177414253228;FOX{D1,D2}:-0.191840930637;PAX5:-0.200806049248;FOSL2:-0.202325647055;IKZF2:-0.204935379543;MEF2{A,B,C,D}:-0.216712277946;SOX{8,9,10}:-0.216760752579;RUNX1..3:-0.221851367593;MYFfamily:-0.22905762452;PITX1..3:-0.236249410496;NR6A1:-0.237407459497;LEF1_TCF7_TCF7L1,2:-0.238947919718;IKZF1:-0.240392771564;ELK1,4_GABP{A,B1}:-0.241019730277;SOX5:-0.24449936161;HIC1:-0.2456625474;NFE2:-0.25244767731;PAX6:-0.257885442917;TFAP2{A,C}:-0.262302909665;OCT4_SOX2{dimer}:-0.275466709124;PBX1:-0.283731100305;STAT5{A,B}:-0.286037756447;POU2F1..3:-0.28727156302;PRRX1,2:-0.29394301536;IRF1,2:-0.29418471669;NFIL3:-0.299367321266;MAZ:-0.303544007645;ZFP161:-0.306868517051;ELF1,2,4:-0.307521602735;RXRA_VDR{dimer}:-0.31739676182;MED-1{core}:-0.320812191556;DMAP1_NCOR{1,2}_SMARC:-0.326336684479;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.353926179563;NHLH1,2:-0.355188117145;ETS1,2:-0.365995188669;SPI1:-0.371858132711;MTF1:-0.38026998986;YY1:-0.381627087499;HOXA9_MEIS1:-0.381673428938;HNF4A_NR2F1,2:-0.385635676954;ZNF148:-0.407972651281;FOXP1:-0.410865910628;HOX{A6,A7,B6,B7}:-0.426471518217;LMO2:-0.429147822677;AHR_ARNT_ARNT2:-0.436255799054;RREB1:-0.458757251345;EGR1..3:-0.470845870416;CEBPA,B_DDIT3:-0.471193494694;ESRRA:-0.47233840059;HIF1A:-0.485123349903;NKX2-3_NKX2-5:-0.485799803385;ZNF143:-0.490900197989;SPIB:-0.492144319938;MYB:-0.492629068138;TFDP1:-0.502104135496;PAX2:-0.514040749917;RFX1:-0.538818096013;NRF1:-0.552215255124;ZEB1:-0.553223761786;POU5F1:-0.557032322715;TOPORS:-0.607535810852;SNAI1..3:-0.610833799439;SP1:-0.642536919165;ATF5_CREB3:-0.644206829423;FOX{F1,F2,J1}:-0.649962964987;GFI1:-0.651300699683;SREBF1,2:-0.671418191947;TGIF1:-0.678574685136;ATF2:-0.681019690716;CREB1:-0.687681342176;GATA6:-0.74736942979;FOXO1,3,4:-0.753493990707;CUX2:-0.762240005097;ZNF423:-0.770189283317;STAT1,3:-0.775472508968;T:-0.781951239471;NR1H4:-0.811998774872;E2F1..5:-0.879782672633;IRF7:-0.913604043717;PAX3,7:-0.925656798821;MYOD1:-0.990834272408;PDX1:-1.01728390555;NANOG:-1.1155455982;NR5A1,2:-1.12997531591;ATF4:-1.13349538463;FOXN1:-1.16033302566;RFX2..5_RFXANK_RFXAP:-1.16703634361;VSX1,2:-1.20164931238;RORA:-1.22287728534;BREu{core}:-1.23742022749;NFY{A,B,C}:-1.28428412346;FOXA2:-1.30410661774;EP300:-1.33205537494;RBPJ:-1.50009942631 | ||
|xref= | |||
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:12750-136A5;search_select_hide=table117:FF:12750-136A5 | |||
}} | }} |
Latest revision as of 18:44, 4 June 2020
Name: | Aortic smooth muscle cell response to IL1b |
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Species: | Human (Homo sapiens) |
Library ID: | CNhs13369 |
Sample type: | time courses |
Genomic View: | UCSC |
RefEX: | Specific genes |
FANTOM CAT: | 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 |
CAGEd-oPOSSUM: | link |
ZENBU report : | link |
Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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CAGE Accession numbers | ||||||||||||||||||||||||||||||||||||||||||||||
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Download raw sequence, BAM & CTSS | ||||||||||||||
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Relative expression to median (log10)
Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.
Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13369
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs13369
Novel motif | Logo | P-value |
---|---|---|
1 | 1 | 0.202 |
10 | 10 | 0.552 |
100 | 100 | 0.443 |
101 | 101 | 0.898 |
102 | 102 | 0.933 |
103 | 103 | 0.227 |
104 | 104 | 0.828 |
105 | 105 | 0.311 |
106 | 106 | 0.00551 |
107 | 107 | 0.0842 |
108 | 108 | 0.239 |
109 | 109 | 0.229 |
11 | 11 | 0.0768 |
110 | 110 | 0.21 |
111 | 111 | 0.103 |
112 | 112 | 0.182 |
113 | 113 | 0.0826 |
114 | 114 | 0.0206 |
115 | 115 | 0.0895 |
116 | 116 | 0.0311 |
117 | 117 | 0.347 |
118 | 118 | 0.339 |
119 | 119 | 0.114 |
12 | 12 | 0.997 |
120 | 120 | 0.0146 |
121 | 121 | 0.766 |
122 | 122 | 0.106 |
123 | 123 | 0.253 |
124 | 124 | 0.879 |
125 | 125 | 0.323 |
126 | 126 | 0.597 |
127 | 127 | 0.982 |
128 | 128 | 0.0435 |
129 | 129 | 0.408 |
13 | 13 | 0.506 |
130 | 130 | 0.313 |
131 | 131 | 0.297 |
132 | 132 | 0.813 |
133 | 133 | 0.838 |
134 | 134 | 0.52 |
135 | 135 | 0.387 |
136 | 136 | 0.667 |
137 | 137 | 0.167 |
138 | 138 | 0.931 |
139 | 139 | 0.193 |
14 | 14 | 0.916 |
140 | 140 | 0.218 |
141 | 141 | 0.736 |
142 | 142 | 0.623 |
143 | 143 | 0.022 |
144 | 144 | 0.302 |
145 | 145 | 0.135 |
146 | 146 | 0.836 |
147 | 147 | 0.153 |
148 | 148 | 0.0888 |
149 | 149 | 0.0556 |
15 | 15 | 0.392 |
150 | 150 | 0.119 |
151 | 151 | 0.757 |
152 | 152 | 0.0407 |
153 | 153 | 0.618 |
154 | 154 | 0.829 |
155 | 155 | 0.0387 |
156 | 156 | 0.661 |
157 | 157 | 0.269 |
158 | 158 | 0.0314 |
159 | 159 | 0.161 |
16 | 16 | 0.094 |
160 | 160 | 0.124 |
161 | 161 | 0.912 |
162 | 162 | 0.0844 |
163 | 163 | 0.95 |
164 | 164 | 0.0168 |
165 | 165 | 0.74 |
166 | 166 | 0.42 |
167 | 167 | 0.546 |
168 | 168 | 0.456 |
169 | 169 | 0.0705 |
17 | 17 | 0.115 |
18 | 18 | 0.089 |
19 | 19 | 0.0458 |
2 | 2 | 0.535 |
20 | 20 | 0.79 |
21 | 21 | 0.297 |
22 | 22 | 0.501 |
23 | 23 | 0.129 |
24 | 24 | 0.942 |
25 | 25 | 0.33 |
26 | 26 | 0.0858 |
27 | 27 | 0.312 |
28 | 28 | 0.456 |
29 | 29 | 0.0932 |
3 | 3 | 0.234 |
30 | 30 | 0.901 |
31 | 31 | 0.306 |
32 | 32 | 1.27625e-4 |
33 | 33 | 0.655 |
34 | 34 | 0.854 |
35 | 35 | 0.157 |
36 | 36 | 0.868 |
37 | 37 | 0.0179 |
38 | 38 | 0.477 |
39 | 39 | 0.297 |
4 | 4 | 0.953 |
40 | 40 | 0.929 |
41 | 41 | 0.618 |
42 | 42 | 0.847 |
43 | 43 | 0.189 |
44 | 44 | 0.0143 |
45 | 45 | 0.548 |
46 | 46 | 0.0513 |
47 | 47 | 0.289 |
48 | 48 | 0.169 |
49 | 49 | 0.449 |
5 | 5 | 0.417 |
50 | 50 | 0.832 |
51 | 51 | 0.635 |
52 | 52 | 0.533 |
53 | 53 | 0.432 |
54 | 54 | 0.523 |
55 | 55 | 0.101 |
56 | 56 | 0.649 |
57 | 57 | 0.384 |
58 | 58 | 0.821 |
59 | 59 | 0.0679 |
6 | 6 | 0.428 |
60 | 60 | 0.387 |
61 | 61 | 0.426 |
62 | 62 | 0.429 |
63 | 63 | 0.191 |
64 | 64 | 0.576 |
65 | 65 | 0.124 |
66 | 66 | 0.548 |
67 | 67 | 0.475 |
68 | 68 | 0.383 |
69 | 69 | 0.787 |
7 | 7 | 0.738 |
70 | 70 | 0.0418 |
71 | 71 | 0.216 |
72 | 72 | 0.777 |
73 | 73 | 0.0193 |
74 | 74 | 0.0376 |
75 | 75 | 0.349 |
76 | 76 | 0.399 |
77 | 77 | 0.0167 |
78 | 78 | 0.556 |
79 | 79 | 0.00343 |
8 | 8 | 0.0179 |
80 | 80 | 0.273 |
81 | 81 | 0.291 |
82 | 82 | 0.0269 |
83 | 83 | 0.852 |
84 | 84 | 0.878 |
85 | 85 | 0.0513 |
86 | 86 | 0.647 |
87 | 87 | 0.136 |
88 | 88 | 0.16 |
89 | 89 | 0.141 |
9 | 9 | 0.422 |
90 | 90 | 0.178 |
91 | 91 | 0.168 |
92 | 92 | 0.17 |
93 | 93 | 0.486 |
94 | 94 | 0.33 |
95 | 95 | 0.243 |
96 | 96 | 0.709 |
97 | 97 | 0.65 |
98 | 98 | 0.768 |
99 | 99 | 0.00807 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs13369
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
EFO:0002091 biological replicate
FF:0000556 human Aortic Smooth Muscle cells 0min after treatment with IL1b sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000548 (animal cell)
0002371 (somatic cell)
0000393 (electrically responsive cell)
0000183 (contractile cell)
0000187 (muscle cell)
0000192 (smooth muscle cell)
0000211 (electrically active cell)
0000255 (eukaryotic cell)
0000359 (vascular associated smooth muscle cell)
0002539 (aortic smooth muscle cell)
UBERON: Anatomy
0000468 (multi-cellular organism)
0001135 (smooth muscle tissue)
0000947 (aorta)
0001637 (artery)
0000483 (epithelium)
0000479 (tissue)
0000055 (vessel)
0004111 (anatomical conduit)
0004120 (mesoderm-derived structure)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0003914 (epithelial tube)
0000025 (tube)
0000477 (anatomical cluster)
0000467 (anatomical system)
0001062 (anatomical entity)
0000480 (anatomical group)
0000119 (cell layer)
0004573 (systemic artery)
0002385 (muscle tissue)
0003509 (arterial blood vessel)
0007500 (epithelial tube open at both ends)
0001981 (blood vessel)
0004237 (blood vessel smooth muscle)
0004695 (arterial system smooth muscle)
0002049 (vasculature)
0010317 (germ layer / neural crest derived structure)
0002111 (artery smooth muscle tissue)
0007798 (vascular system)
0001015 (musculature)
0004178 (aorta smooth muscle tissue)
0002204 (musculoskeletal system)
0004535 (cardiovascular system)
0004571 (systemic arterial system)
0010191 (aortic system)
0000383 (musculature of body)
0004572 (arterial system)
0004537 (blood vasculature)
0001009 (circulatory system)
FF: FANTOM5
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000350 (experimentally modified sample)
0000344 (0 minute sample)
0000340 (IL1-beta treatment sample)
0000556 (human Aortic Smooth Muscle cells 0min after treatment with IL1b sample)
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
CL:0000355 (multi-potent skeletal muscle stem cell)
CL:0000222 (mesodermal cell)
CL:0000514 (smooth muscle myoblast)