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Coexpression cluster:C2579

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Full id: C2579_spinal_cerebellum_amygdala_occipital_pineal_medial_CD4



Phase1 CAGE Peaks

Hg19::chr1:26093536..26093557,+p@chr1:26093536..26093557
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Hg19::chr1:26093961..26094017,+p@chr1:26093961..26094017
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Hg19::chr1:26094071..26094085,+p@chr1:26094071..26094085
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Hg19::chr1:26094142..26094180,+p@chr1:26094142..26094180
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism3.20e-51115
neural tube3.20e-3457
neural rod3.20e-3457
future spinal cord3.20e-3457
neural keel3.20e-3457
central nervous system2.45e-3382
regional part of brain1.49e-3159
regional part of nervous system2.97e-3194
nervous system2.97e-3194
brain1.75e-2869
future brain1.75e-2869
anterior neural tube1.97e-2842
regional part of forebrain2.82e-2841
forebrain2.82e-2841
future forebrain2.82e-2841
neurectoderm2.14e-2590
neural plate2.24e-2586
presumptive neural plate2.24e-2586
gray matter1.71e-2334
brain grey matter1.71e-2334
telencephalon2.09e-2334
regional part of telencephalon9.43e-2333
cerebral hemisphere5.30e-2232
pre-chordal neural plate1.07e-1961
cerebral cortex1.00e-1725
pallium1.00e-1725
regional part of cerebral cortex3.75e-1722
anterior region of body1.88e-16129
craniocervical region1.88e-16129
neocortex1.03e-1520
head7.67e-15123
ectoderm1.54e-13173
presumptive ectoderm1.54e-13173
ectoderm-derived structure3.14e-13169
basal ganglion2.89e-079
nuclear complex of neuraxis2.89e-079
aggregate regional part of brain2.89e-079
collection of basal ganglia2.89e-079
cerebral subcortex2.89e-079
nucleus of brain3.28e-079
neural nucleus3.28e-079
posterior neural tube3.54e-0715
chordal neural plate3.54e-0715
temporal lobe4.49e-077


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.