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Coexpression cluster:C2191

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Full id: C2191_pineal_medial_occipital_parietal_middle_temporal_postcentral



Phase1 CAGE Peaks

Hg19::chr12:121099167..121099179,+p@chr12:121099167..121099179
+
Hg19::chr20:48099892..48099917,-p@chr20:48099892..48099917
-
Hg19::chr20:48100770..48100790,-p2@KCNB1
Hg19::chr9:100854293..100854313,-p@chr9:100854293..100854313
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism5.96e-53115
central nervous system3.75e-4082
brain9.94e-4069
future brain9.94e-4069
regional part of nervous system2.03e-3994
nervous system2.03e-3994
regional part of brain5.26e-3659
neural tube7.42e-3657
neural rod7.42e-3657
future spinal cord7.42e-3657
neural keel7.42e-3657
regional part of forebrain1.81e-3341
forebrain1.81e-3341
future forebrain1.81e-3341
anterior neural tube2.72e-3242
telencephalon1.07e-2634
gray matter2.25e-2634
brain grey matter2.25e-2634
regional part of telencephalon1.16e-2533
cerebral hemisphere1.98e-2532
neural plate5.94e-2586
presumptive neural plate5.94e-2586
neurectoderm3.78e-2490
anterior region of body4.08e-23129
craniocervical region4.08e-23129
head2.36e-22123
regional part of cerebral cortex2.89e-2122
pre-chordal neural plate3.42e-2061
ectoderm-derived structure3.67e-20169
ectoderm6.49e-20173
presumptive ectoderm6.49e-20173
cerebral cortex2.05e-1925
pallium2.05e-1925
neocortex2.62e-1920
organism subdivision4.47e-09365
basal ganglion1.16e-089
nuclear complex of neuraxis1.16e-089
aggregate regional part of brain1.16e-089
collection of basal ganglia1.16e-089
cerebral subcortex1.16e-089
nucleus of brain2.14e-089
neural nucleus2.14e-089
diencephalon3.17e-087
future diencephalon3.17e-087
tube3.78e-08194
gyrus4.44e-086
anatomical cluster4.93e-07286
telencephalic nucleus5.40e-077
temporal lobe5.68e-077
anatomical conduit5.82e-07241


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.