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Coexpression cluster:C705

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Full id: C705_small_cerebellum_parietal_occipital_temporal_amygdala_olfactory



Phase1 CAGE Peaks

Hg19::chr17:47653077..47653091,+p3@NXPH3
Hg19::chr20:30573367..30573378,+p@chr20:30573367..30573378
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Hg19::chr20:30574743..30574753,+p@chr20:30574743..30574753
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Hg19::chr20:30574762..30574771,+p@chr20:30574762..30574771
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Hg19::chr6:102297713..102297717,+p@chr6:102297713..102297717
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Hg19::chr6:102357270..102357274,+p@chr6:102357270..102357274
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Hg19::chr6:102358656..102358697,+p@chr6:102358656..102358697
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Hg19::chr6:102365472..102365475,+p@chr6:102365472..102365475
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Hg19::chr6:102367060..102367078,+p@chr6:102367060..102367078
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Hg19::chr6:102368618..102368631,+p@chr6:102368618..102368631
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Hg19::chr6:102374094..102374097,+p@chr6:102374094..102374097
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Hg19::chr7:29274566..29274570,+p@chr7:29274566..29274570
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
adult organism9.94e-31115
neural tube2.53e-2957
neural rod2.53e-2957
future spinal cord2.53e-2957
neural keel2.53e-2957
regional part of nervous system5.92e-2994
nervous system5.92e-2994
central nervous system5.76e-2782
brain1.13e-2569
future brain1.13e-2569
regional part of brain4.13e-2559
regional part of forebrain5.90e-2541
forebrain5.90e-2541
future forebrain5.90e-2541
anterior neural tube7.13e-2442
neurectoderm1.02e-2390
neural plate1.06e-2286
presumptive neural plate1.06e-2286
gray matter5.08e-2134
brain grey matter5.08e-2134
telencephalon1.29e-2034
regional part of telencephalon6.51e-2033
cerebral hemisphere1.07e-1932
pre-chordal neural plate6.42e-1761
regional part of cerebral cortex9.10e-1722
ectoderm1.60e-16173
presumptive ectoderm1.60e-16173
ectoderm-derived structure1.30e-15169
neocortex3.37e-1520
cerebral cortex6.90e-1525
pallium6.90e-1525
anterior region of body1.93e-13129
craniocervical region1.93e-13129
head2.03e-13123
basal ganglion7.58e-089
nuclear complex of neuraxis7.58e-089
aggregate regional part of brain7.58e-089
collection of basal ganglia7.58e-089
cerebral subcortex7.58e-089
nucleus of brain1.14e-079
neural nucleus1.14e-079
organ1.48e-07511
multi-cellular organism9.13e-07659
posterior neural tube9.25e-0715
chordal neural plate9.25e-0715


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.