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{{f5samples
{{f5samples
|id=FF:10172-103C1
|DRA_sample_Accession=CAGE@SAMD00005173
|name=occipital cortex - adult, donor10196
|accession_numbers=CAGE;DRX008690;DRR009562;DRZ000987;DRZ002372;DRZ012337;DRZ013722
|sample_id=10172
|ancestors_in_anatomy_facet=UBERON:0000468,UBERON:0007023,UBERON:0000955,UBERON:0002021,UBERON:0000956,UBERON:0000479,UBERON:0004121,UBERON:0000064,UBERON:0010314,UBERON:0011216,UBERON:0000062,UBERON:0000061,UBERON:0000465,UBERON:0000481,UBERON:0000073,UBERON:0000477,UBERON:0003528,UBERON:0002791,UBERON:0000467,UBERON:0002619,UBERON:0001062,UBERON:0000480,UBERON:0002616,UBERON:0002780,UBERON:0002020,UBERON:0010317,UBERON:0001017,UBERON:0001016,UBERON:0001869,UBERON:0001893,UBERON:0001890,UBERON:0000203,UBERON:0001950
|rna_tube_id=103C1
|rna_box=103
|rna_position=C1
|sample_cell_lot=NA
|sample_cell_catalog=NA
|sample_company=
|rna_lot_number=
|rna_catalog_number=
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_dev_stage=
|sample_tissue=occipital cortex
|sample_donor(cell lot)=donor: 10196
|sample_sex=female
|sample_age=60
|sample_ethnicity=
|rna_rin=
|rna_od260/230=2.21
|rna_od260/280=1.95
|sample_cell_type=CELL MIXTURE - tissue sample
|sample_cell_line=
|sample_collaboration=Peter Heutink
|sample_experimental_condition=
|sample_disease=
|rna_sample_type=total RNA
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_weight_ug=34.20825
|rna_concentration=0.45611
|sample_note=
|profile_hcage=CNhs13798,LSID1086,release014,COMPLETED
|profile_cagescan=
|profile_srnaseq=
|profile_rnaseq=
|ancestors_in_cell_lineage_facet=
|ancestors_in_cell_lineage_facet=
|ancestors_in_anatomy_facet=UBERON:0000025,UBERON:0000033,UBERON:0000061,UBERON:0000062,UBERON:0000064,UBERON:0000073,UBERON:0000153,UBERON:0000465,UBERON:0000467,UBERON:0000468,UBERON:0000475,UBERON:0000477,UBERON:0000479,UBERON:0000480,UBERON:0000481,UBERON:0000922,UBERON:0000923,UBERON:0000924,UBERON:0000955,UBERON:0000956,UBERON:0001016,UBERON:0001017,UBERON:0001049,UBERON:0001062,UBERON:0001869,UBERON:0001890,UBERON:0001893,UBERON:0001950,UBERON:0002021,UBERON:0002050,UBERON:0002346,UBERON:0002532,UBERON:0002616,UBERON:0002619,UBERON:0002780,UBERON:0002791,UBERON:0003056,UBERON:0003075,UBERON:0003080,UBERON:0004121,UBERON:0005068,UBERON:0005291,UBERON:0005423,UBERON:0005743,UBERON:0006598,UBERON:0007023,UBERON:0007135,UBERON:0007284
|ancestors_in_disease_facet=
|ancestors_in_disease_facet=
|sample_description=
|ancestors_in_ff_facet=FF:0000102,FF:0000210,FF:0000101,FF:0000001,FF:0000998,FF:0000004,FF:0010163
|comment=
|created_by=
|creation_date=
|data_phase=2
|datafreeze_phase=2
|def=
|expression_enrichment_score=chr9:77112244..77112262,+!p1@RORB!2.40!279.14!RORB;;chr21:34442439..34442455,+!p1@OLIG1!2.35!222.46!OLIG1;;chr19:57352087..57352102,-!p1@PEG3,p1@ZIM2!2.34!216.80!PEG3;;chr7:100065686..100065701,-!p2@TSC22D4!2.21!161.53!TSC22D4;;chr9:114287433..114287513,+!p1@ZNF483!2.15!347.16!ZNF483;;chr4:81118647..81118666,+!p1@PRDM8!2.15!184.21!PRDM8;;chr10:64134120..64134183,+!p1@ZNF365!2.01!120.44!ZNF365;;chr17:53342311..53342400,+!p1@HLF!1.99!110.52!HLF;;chr2:2334997..2335053,-!p1@MYT1L!1.96!89.27!MYT1L;;chr17:38821373..38821440,-!p1@KRT222,p2@SMARCE1!1.94!86.43!SMARCE1;;chr5:88178983..88179012,-!p1@MEF2C!1.93!607.88!MEF2C;;chr2:60781201..60781258,-!p3@BCL11A!1.93!85.02!BCL11A;;chrX:25034067..25034088,-!p1@ARX!1.93!83.60!ARX;;chr8:40755333..40755352,-!p1@ZMAT4!1.91!80.77!ZMAT4;;chr2:162272785..162272836,+!p1@TBR1!1.90!79.35!TBR1;;chr2:95963052..95963106,+!p1@KCNIP3!1.87!73.68!KCNIP3;;chr11:61520075..61520136,+!p1@C11orf9!1.80!127.53!C11orf9;;chr18:53070846..53070902,-!p6@TCF4!1.80!62.35!TCF4;;chr21:34442540..34442560,+!p2@OLIG1!1.78!59.51!OLIG1;;chr14:29235961..29236008,+!p1@FOXG1!1.77!58.10!FOXG1;;chr15:80735246..80735321,+!p3@ARNT2!1.74!53.84!ARNT2;;chr2:166326200..166326216,+!p1@CSRNP3!1.72!73.68!CSRNP3;;chr4:57547454..57547469,-!p1@HOPX!1.72!51.01!HOPX;;chr22:38380543..38380569,-!p1@SOX10!1.70!49.59!SOX10;;chr12:106976774..106976788,+!p1@RFX4!1.70!49.59!RFX4;;chr9:77112225..77112238,+!p2@RORB!1.70!49.59!RORB;;chr3:181429704..181429722,+!p1@SOX2!1.69!48.18!SOX2;;chr10:48355030..48355090,+!p1@ZNF488!1.67!58.10!ZNF488;;chr19:13135582..13135600,+!p3@NFIX!1.67!45.34!NFIX;;chr15:80733570..80733659,+!p2@ARNT2!1.65!43.93!ARNT2;;chr5:88179017..88179046,-!p2@MEF2C!1.64!165.78!MEF2C;;chr17:37764128..37764258,-!p1@NEUROD2!1.64!42.51!NEUROD2;;chr11:125034640..125034655,+!p1@PKNOX2!1.62!41.09!PKNOX2;;chr2:105470562..105470582,+!p@chr2:105470562..105470582,+!1.62!41.09!POU3F3;;chr19:13135386..13135435,+!p4@NFIX!1.58!36.84!NFIX;;chr3:181429741..181429767,+!p2@SOX2!1.56!35.42!SOX2;;chr11:113930425..113930471,+!p1@ZBTB16!1.53!46.76!ZBTB16;;chr8:53322304..53322340,-!p1@ST18!1.53!32.59!ST18;;chr10:119302232..119302265,+!p1@EMX2!1.51!31.17!EMX2;;chr19:38085768..38085821,+!p1@ZNF540!1.50!45.34!ZNF540;;chr2:95963120..95963136,+!p2@KCNIP3!1.49!29.76!KCNIP3;;chr2:162272889..162272915,+!p2@TBR1!1.47!28.34!TBR1;;chr12:103351444..103351461,+!p1@ASCL1!1.47!28.34!ASCL1;;chr12:106976678..106976708,+!p2@RFX4!1.47!28.34!RFX4;;chr10:64133862..64133884,+!p4@ZNF365!1.45!26.92!ZNF365;;chr3:141105235..141105307,+!p7@ZBTB38!1.45!26.92!ZBTB38;;chr12:26277817..26277863,-!p2@BHLHE41!1.44!35.42!BHLHE41;;chr2:162272716..162272753,+!p3@TBR1!1.42!25.51!TBR1;;chr9:126773880..126773895,+!p2@LHX2!1.42!25.51!LHX2;;chr7:63505799..63505904,+!p1@ZNF727!1.42!25.51!ZNF727;;chr3:141105705..141105770,+!p4@ZBTB38!1.41!29.76!ZBTB38;;chr2:105470536..105470556,+!p@chr2:105470536..105470556,+!1.40!24.09!POU3F3;;chr8:145560111..145560165,-!p2@SCRT1!1.40!24.09!SCRT1;;chr14:29234581..29234601,+!p2@FOXG1!1.40!24.09!FOXG1;;chr21:34398234..34398250,+!p1@OLIG2!1.40!24.09!OLIG2;;chr20:42544782..42544828,+!p4@TOX2!1.37!22.67!TOX2;;chr2:180726291..180726311,-!p1@ZNF385B!1.37!22.67!ZNF385B;;chrX:85969626..85969664,+!p1@DACH2!1.37!22.67!DACH2;;chr2:145277882..145277967,-!p3@ZEB2!1.35!36.84!ZEB2;;chr11:8102846..8102892,+!p1@TUB!1.35!29.76!TUB;;chr15:80696703..80696754,+!p1@ARNT2!1.35!28.34!ARNT2;;chr15:31658288..31658338,+!p4@KLF13!1.35!21.25!KLF13;;chr19:57352109..57352153,-!p2@ZIM2!1.35!21.25!ZIM2;;chr14:58797974..58798011,+!p3@ARID4A!1.35!21.25!ARID4A;;chr12:54785074..54785122,-!p2@ZNF385A!1.33!31.17!ZNF385A;;chr1:214161272..214161322,+!p1@PROX1!1.33!28.34!PROX1;;chr19:46801639..46801699,+!p1@HIF3A!1.32!19.84!HIF3A;;chr19:13135566..13135577,+!p9@NFIX!1.32!19.84!NFIX;;chr2:162273254..162273267,+!p6@TBR1!1.32!19.84!TBR1;;chr2:180726331..180726344,-!p5@ZNF385B!1.32!19.84!ZNF385B;;chr9:126774018..126774055,+!p1@LHX2!1.32!19.84!LHX2;;chr2:162273196..162273210,+!p5@TBR1!1.29!18.42!TBR1;;chr2:162273241..162273253,+!p4@TBR1!1.29!18.42!TBR1;;chr2:166428861..166428883,+!p3@CSRNP3!1.29!18.42!CSRNP3;;chr10:31610110..31610159,+!p2@ZEB1!1.29!18.42!ZEB1;;chr11:125034605..125034636,+!p2@PKNOX2!1.29!18.42!PKNOX2;;chr11:31832658..31832681,-!p1@PAX6!1.29!18.42!PAX6;;chr12:26277956..26277980,-!p1@BHLHE41!1.28!63.76!BHLHE41;;chr2:192015750..192015793,-!p2@STAT4!1.28!24.09!STAT4;;chr17:7492684..7492778,-!p2@SOX15!1.27!36.84!SOX15;;chr2:162273101..162273118,+!p7@TBR1!1.26!17.00!TBR1;;chr2:166428839..166428859,+!p2@CSRNP3!1.26!17.00!CSRNP3;;chr1:217263131..217263207,-!p4@ESRRG!1.26!17.00!ESRRG;;chr6:15401104..15401166,+!p5@JARID2!1.26!17.00!JARID2;;chr7:31380292..31380351,-!p1@NEUROD6!1.26!17.00!NEUROD6;;chr8:53322347..53322378,-!p2@ST18!1.26!17.00!ST18;;chr10:64134045..64134083,+!p3@ZNF365!1.26!17.00!ZNF365;;chr6:126112039..126112062,+!p8@NCOA7!1.24!19.84!NCOA7;;chr8:145560371..145560449,-!p1@SCRT1!1.22!15.59!SCRT1;;chr21:39870339..39870443,-!p1@ERG!1.22!15.59!ERG;;chr16:1031762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|fantom_cat=http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000955;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0000956;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001016;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001890;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0001893;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0002021;;http://fantom.gsc.riken.jp/5/suppl/Hon_et_al_2016/vis/#/ontologies/UBERON:0003528
|ffid_belonging_in_development=UBERON:0002532,UBERON:0006601,UBERON:0010316
|fonse_cell_line=
|fonse_cell_line=
|fonse_cell_line_closure=
|fonse_cell_line_closure=
Line 66: Line 41:
|fonse_treatment=
|fonse_treatment=
|fonse_treatment_closure=
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|rna_box=103
|rna_catalog_number=
|rna_concentration=0.45611
|rna_extraction_protocol=OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0
|rna_lot_number=
|rna_od260/230=2.21
|rna_od260/280=1.95
|rna_position=C1
|rna_rin=
|rna_sample_type=total RNA
|rna_tube_id=103C1
|rna_weight_ug=34.20825
|sample_age=60
|sample_category=tissues
|sample_cell_catalog=NA
|sample_cell_line=
|sample_cell_lot=NA
|sample_cell_type=CELL MIXTURE - tissue sample
|sample_collaboration=Peter Heutink
|sample_company=
|sample_description=
|sample_dev_stage=
|sample_disease=
|sample_donor(cell lot)=donor: 10196
|sample_ethnicity=
|sample_experimental_condition=
|sample_gostat=GO:0044464;cell part;0!GO:0005622;intracellular;0!GO:0044424;intracellular part;2.51722459339303e-272!GO:0005737;cytoplasm;7.03274858066242e-146!GO:0043226;organelle;1.83933100727468e-105!GO:0043229;intracellular organelle;6.75827775862751e-105!GO:0043227;membrane-bound organelle;1.39906714831906e-97!GO:0043231;intracellular membrane-bound organelle;1.99238562522615e-97!GO:0044444;cytoplasmic part;2.78697223894782e-97!GO:0044422;organelle part;1.35718295835874e-69!GO:0044446;intracellular organelle part;1.17078457964465e-68!GO:0032991;macromolecular complex;3.68234199998967e-68!GO:0005515;protein binding;1.29784489587146e-58!GO:0030529;ribonucleoprotein complex;8.47677128387784e-47!GO:0016043;cellular component organization and biogenesis;1.4015733823655e-45!GO:0003723;RNA binding;9.63624988378728e-44!GO:0005739;mitochondrion;3.32365407692497e-43!GO:0033036;macromolecule localization;1.01643268905042e-38!GO:0015031;protein transport;3.28539211883998e-38!GO:0043234;protein complex;1.26042460234183e-37!GO:0008104;protein localization;4.15242930785273e-35!GO:0043233;organelle lumen;8.96198516828609e-35!GO:0031974;membrane-enclosed lumen;8.96198516828609e-35!GO:0045184;establishment of protein localization;1.17944794100965e-34!GO:0031090;organelle membrane;1.50086200972155e-33!GO:0044429;mitochondrial part;4.53198402670445e-33!GO:0044428;nuclear part;6.65564822953233e-33!GO:0046907;intracellular transport;2.2776546164125e-31!GO:0006396;RNA processing;2.1923656692045e-29!GO:0016071;mRNA metabolic process;2.39380638512277e-29!GO:0043170;macromolecule metabolic process;8.97888025483377e-29!GO:0044238;primary metabolic process;1.26702002984683e-28!GO:0044237;cellular metabolic process;1.41303197219895e-28!GO:0051649;establishment of cellular localization;5.95626891760295e-28!GO:0051641;cellular localization;6.03366204432677e-28!GO:0005829;cytosol;3.20442755183766e-27!GO:0005634;nucleus;7.07466356429534e-27!GO:0031975;envelope;2.8181107678025e-26!GO:0031967;organelle envelope;3.2070503340609e-26!GO:0008380;RNA splicing;3.86482926199475e-26!GO:0019538;protein metabolic process;5.26978710282265e-26!GO:0005840;ribosome;9.52934117265834e-26!GO:0006397;mRNA processing;2.46710325525242e-25!GO:0006886;intracellular protein transport;7.16422009080648e-24!GO:0044260;cellular macromolecule metabolic process;3.45038348760173e-23!GO:0006119;oxidative phosphorylation;3.47249357647521e-23!GO:0016192;vesicle-mediated transport;1.07694913335146e-22!GO:0044267;cellular protein metabolic process;1.38753479181587e-22!GO:0006412;translation;2.86334216897738e-22!GO:0003735;structural constituent of ribosome;1.37960520747903e-21!GO:0005740;mitochondrial envelope;1.37960520747903e-21!GO:0031966;mitochondrial membrane;5.79412062142771e-21!GO:0006996;organelle organization and biogenesis;1.05554353998204e-19!GO:0031981;nuclear lumen;1.63925346784224e-19!GO:0044455;mitochondrial membrane part;6.29032935900364e-19!GO:0019866;organelle inner membrane;1.66977504634811e-18!GO:0000166;nucleotide binding;2.05950557080379e-18!GO:0005743;mitochondrial inner membrane;3.98191390236716e-18!GO:0033279;ribosomal subunit;6.50275805556214e-18!GO:0005681;spliceosome;1.43610114897529e-17!GO:0016818;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides;3.28361874294056e-17!GO:0016462;pyrophosphatase activity;3.86209571653671e-17!GO:0016817;hydrolase activity, acting on acid anhydrides;4.38918134334537e-17!GO:0005794;Golgi apparatus;6.29975206056281e-17!GO:0065003;macromolecular complex assembly;8.41258303021604e-17!GO:0043283;biopolymer metabolic process;9.61994998558357e-17!GO:0005746;mitochondrial respiratory chain;1.35748895215371e-16!GO:0031982;vesicle;1.35748895215371e-16!GO:0017111;nucleoside-triphosphatase activity;3.05059256898934e-16!GO:0009058;biosynthetic process;3.79503794328332e-16!GO:0031410;cytoplasmic vesicle;6.5510292319773e-16!GO:0009059;macromolecule biosynthetic process;9.62017060452951e-16!GO:0022613;ribonucleoprotein complex biogenesis and assembly;1.34638682662408e-15!GO:0050136;NADH dehydrogenase (quinone) activity;1.95210933954845e-15!GO:0003954;NADH dehydrogenase activity;1.95210933954845e-15!GO:0008137;NADH dehydrogenase (ubiquinone) activity;1.95210933954845e-15!GO:0006457;protein folding;2.12069787337042e-15!GO:0044249;cellular biosynthetic process;2.88022291056919e-15!GO:0022607;cellular component assembly;4.72826531394539e-15!GO:0031988;membrane-bound vesicle;5.07438652131909e-15!GO:0006512;ubiquitin cycle;5.87976760690913e-15!GO:0016655;oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor;7.45184210628202e-15!GO:0016023;cytoplasmic membrane-bound vesicle;2.5098702992155e-14!GO:0031980;mitochondrial lumen;4.71071589622101e-14!GO:0005759;mitochondrial matrix;4.71071589622101e-14!GO:0010467;gene expression;9.21515423860758e-14!GO:0032553;ribonucleotide binding;1.04957895641612e-13!GO:0032555;purine ribonucleotide binding;1.04957895641612e-13!GO:0030964;NADH dehydrogenase complex (quinone);2.32208086363439e-13!GO:0045271;respiratory chain complex I;2.32208086363439e-13!GO:0005747;mitochondrial respiratory chain complex I;2.32208086363439e-13!GO:0044445;cytosolic part;2.33373433671305e-13!GO:0016874;ligase activity;4.27696425144381e-13!GO:0042775;organelle ATP synthesis coupled electron transport;4.50208773428184e-13!GO:0042773;ATP synthesis coupled electron transport;4.50208773428184e-13!GO:0022618;protein-RNA complex assembly;4.60563490474336e-13!GO:0006120;mitochondrial electron transport, NADH to ubiquinone;6.2183831380745e-13!GO:0017076;purine nucleotide binding;1.33471313674124e-12!GO:0005654;nucleoplasm;1.49521554599392e-12!GO:0043412;biopolymer modification;4.26408262001321e-12!GO:0043228;non-membrane-bound organelle;4.4309890331001e-12!GO:0043232;intracellular non-membrane-bound organelle;4.4309890331001e-12!GO:0045045;secretory pathway;4.44070972028187e-12!GO:0048193;Golgi vesicle transport;4.48773298056698e-12!GO:0005830;cytosolic ribosome (sensu Eukaryota);9.10080299404295e-12!GO:0043687;post-translational protein modification;1.19148890801945e-11!GO:0012505;endomembrane system;1.2424182951273e-11!GO:0044451;nucleoplasm part;1.51159429995404e-11!GO:0006464;protein modification process;4.10736623984347e-11!GO:0048770;pigment granule;4.24999071880284e-11!GO:0042470;melanosome;4.24999071880284e-11!GO:0019829;cation-transporting ATPase activity;5.98914110449457e-11!GO:0008135;translation factor activity, nucleic acid binding;7.08969994378972e-11!GO:0006605;protein targeting;8.3078881327067e-11!GO:0046961;hydrogen ion transporting ATPase activity, rotational mechanism;8.36336898331985e-11!GO:0051082;unfolded protein binding;2.71058406191385e-10!GO:0016651;oxidoreductase activity, acting on NADH or NADPH;3.94009724086775e-10!GO:0008565;protein transporter activity;4.93828913992441e-10!GO:0015935;small ribosomal subunit;8.65343221816843e-10!GO:0003924;GTPase activity;1.19268715147443e-09!GO:0030135;coated vesicle;1.19677606824212e-09!GO:0006810;transport;1.23615174233778e-09!GO:0046933;hydrogen ion transporting ATP synthase activity, rotational mechanism;2.06518424543074e-09!GO:0000502;proteasome complex (sensu Eukaryota);2.08675778611665e-09!GO:0051603;proteolysis involved in cellular protein catabolic process;3.40956131227293e-09!GO:0015986;ATP synthesis coupled proton transport;3.54168479134471e-09!GO:0015985;energy coupled proton transport, down electrochemical gradient;3.54168479134471e-09!GO:0006511;ubiquitin-dependent protein catabolic process;3.57128015585338e-09!GO:0015934;large ribosomal subunit;6.03216478998951e-09!GO:0019941;modification-dependent protein catabolic process;6.06759259685191e-09!GO:0043632;modification-dependent macromolecule catabolic process;6.06759259685191e-09!GO:0044257;cellular protein catabolic process;7.01719280508949e-09!GO:0051186;cofactor metabolic process;7.51913426260749e-09!GO:0006413;translational initiation;8.27534779376588e-09!GO:0044265;cellular macromolecule catabolic process;9.00365436860043e-09!GO:0006793;phosphorus metabolic process;1.09375791272672e-08!GO:0006796;phosphate metabolic process;1.09375791272672e-08!GO:0000398;nuclear mRNA splicing, via spliceosome;1.41927414361041e-08!GO:0000375;RNA splicing, via transesterification reactions;1.41927414361041e-08!GO:0000377;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile;1.41927414361041e-08!GO:0007264;small GTPase mediated signal transduction;1.42019674786357e-08!GO:0032559;adenyl ribonucleotide binding;1.77982364011324e-08!GO:0005761;mitochondrial ribosome;2.04757148009423e-08!GO:0000313;organellar ribosome;2.04757148009423e-08!GO:0006446;regulation of translational initiation;2.05942610019534e-08!GO:0003743;translation initiation factor activity;2.18592981540131e-08!GO:0016604;nuclear body;2.19332560295209e-08!GO:0005768;endosome;2.43343468202067e-08!GO:0015630;microtubule cytoskeleton;2.60700138163607e-08!GO:0008639;small protein conjugating enzyme activity;2.80861002762211e-08!GO:0006139;nucleobase, nucleoside, nucleotide and nucleic acid metabolic process;3.35032175744555e-08!GO:0044431;Golgi apparatus part;3.74779320520635e-08!GO:0015631;tubulin binding;3.81576675415248e-08!GO:0005525;GTP binding;4.78581922443235e-08!GO:0004842;ubiquitin-protein ligase activity;4.88222382369898e-08!GO:0008092;cytoskeletal protein binding;4.94892974988323e-08!GO:0005524;ATP binding;6.52552478389863e-08!GO:0032940;secretion by cell;7.42896482065709e-08!GO:0006754;ATP biosynthetic process;1.06545753022941e-07!GO:0006753;nucleoside phosphate metabolic process;1.06545753022941e-07!GO:0016607;nuclear speck;1.07978930866626e-07!GO:0043005;neuron projection;1.08235932778008e-07!GO:0008134;transcription factor binding;1.18461175175132e-07!GO:0030554;adenyl nucleotide binding;1.67810890199386e-07!GO:0046034;ATP metabolic process;1.75295218807007e-07!GO:0009141;nucleoside triphosphate metabolic process;1.88801301937096e-07!GO:0051234;establishment of localization;1.88801301937096e-07!GO:0042625;ATPase activity, coupled to transmembrane movement of ions;1.93215865266547e-07!GO:0044248;cellular catabolic process;2.09436092900776e-07!GO:0015078;hydrogen ion transmembrane transporter activity;2.30119622302338e-07!GO:0015077;monovalent inorganic cation transmembrane transporter activity;2.31312519504149e-07!GO:0016469;proton-transporting two-sector ATPase complex;2.68001435931424e-07!GO:0005083;small GTPase regulator activity;2.74258269395733e-07!GO:0051179;localization;2.76210691476408e-07!GO:0043285;biopolymer catabolic process;2.87715824446104e-07!GO:0006164;purine nucleotide biosynthetic process;2.99379685343692e-07!GO:0019787;small conjugating protein ligase activity;3.23570519965962e-07!GO:0009060;aerobic respiration;3.31859567282997e-07!GO:0009152;purine ribonucleotide biosynthetic process;3.61963414713415e-07!GO:0006163;purine nucleotide metabolic process;4.18031672105198e-07!GO:0009205;purine ribonucleoside triphosphate metabolic process;4.28348729870387e-07!GO:0009144;purine nucleoside triphosphate metabolic process;4.28348729870387e-07!GO:0009199;ribonucleoside triphosphate metabolic process;4.28348729870387e-07!GO:0009206;purine ribonucleoside triphosphate biosynthetic process;4.64261273921534e-07!GO:0009145;purine nucleoside triphosphate biosynthetic process;4.64261273921534e-07!GO:0009142;nucleoside triphosphate biosynthetic process;4.738055010248e-07!GO:0009201;ribonucleoside triphosphate biosynthetic process;4.738055010248e-07!GO:0030163;protein catabolic process;5.18620626513897e-07!GO:0009150;purine ribonucleotide metabolic process;5.31457983959373e-07!GO:0007010;cytoskeleton organization and biogenesis;5.41173354483176e-07!GO:0009259;ribonucleotide metabolic process;5.45727655322694e-07!GO:0006913;nucleocytoplasmic transport;5.95026595342535e-07!GO:0031965;nuclear membrane;6.55559494293764e-07!GO:0045333;cellular respiration;6.70980372763089e-07!GO:0019717;synaptosome;7.70860816560626e-07!GO:0051169;nuclear transport;7.76673419057963e-07!GO:0016887;ATPase activity;7.76673419057963e-07!GO:0016310;phosphorylation;7.77727325614581e-07!GO:0006732;coenzyme metabolic process;8.13790766864209e-07!GO:0048475;coated membrane;8.52284710914987e-07!GO:0030117;membrane coat;8.52284710914987e-07!GO:0032561;guanyl ribonucleotide binding;8.85033023609621e-07!GO:0019001;guanyl nucleotide binding;8.85033023609621e-07!GO:0009260;ribonucleotide biosynthetic process;8.85033023609621e-07!GO:0005730;nucleolus;8.98141102045072e-07!GO:0006461;protein complex assembly;9.86759845237554e-07!GO:0007399;nervous system development;9.90053573270151e-07!GO:0030695;GTPase regulator activity;9.96360633595199e-07!GO:0016044;membrane organization and biogenesis;1.26080626345228e-06!GO:0009057;macromolecule catabolic process;1.50512992033733e-06!GO:0042623;ATPase activity, coupled;2.02956564085713e-06!GO:0048471;perinuclear region of cytoplasm;2.24514090756277e-06!GO:0005842;cytosolic large ribosomal subunit (sensu Eukaryota);2.40121215050384e-06!GO:0030136;clathrin-coated vesicle;3.4132740248296e-06!GO:0005783;endoplasmic reticulum;3.77879073654715e-06!GO:0009055;electron carrier activity;4.51187324973164e-06!GO:0045259;proton-transporting ATP synthase complex;4.53680170133488e-06!GO:0000139;Golgi membrane;5.02083152770285e-06!GO:0016879;ligase activity, forming carbon-nitrogen bonds;5.55254962322133e-06!GO:0016881;acid-amino acid ligase activity;5.56900755320442e-06!GO:0005874;microtubule;6.02058062052891e-06!GO:0005843;cytosolic small ribosomal subunit (sensu Eukaryota);6.49753698183272e-06!GO:0015405;P-P-bond-hydrolysis-driven transmembrane transporter activity;7.85411358128863e-06!GO:0015399;primary active transmembrane transporter activity;7.85411358128863e-06!GO:0016070;RNA metabolic process;8.57415969851656e-06!GO:0005635;nuclear envelope;8.91788473338261e-06!GO:0006403;RNA localization;9.9533026743987e-06!GO:0032446;protein modification by small protein conjugation;1.13118341516123e-05!GO:0006099;tricarboxylic acid cycle;1.13478446608223e-05!GO:0046356;acetyl-CoA catabolic process;1.13478446608223e-05!GO:0019899;enzyme binding;1.16560868392704e-05!GO:0008017;microtubule binding;1.35386509772553e-05!GO:0050657;nucleic acid transport;1.42596564529245e-05!GO:0051236;establishment of RNA localization;1.42596564529245e-05!GO:0050658;RNA transport;1.42596564529245e-05!GO:0030120;vesicle coat;1.47698331185582e-05!GO:0030662;coated vesicle membrane;1.47698331185582e-05!GO:0008287;protein serine/threonine phosphatase complex;1.51020983419069e-05!GO:0016567;protein ubiquitination;1.77805075755903e-05!GO:0022890;inorganic cation transmembrane transporter activity;2.14047090755059e-05!GO:0005798;Golgi-associated vesicle;2.25291868469587e-05!GO:0005643;nuclear pore;2.27737200321342e-05!GO:0044440;endosomal part;2.28719810453371e-05!GO:0010008;endosome membrane;2.28719810453371e-05!GO:0009109;coenzyme catabolic process;2.52446803514822e-05!GO:0000245;spliceosome assembly;2.7005899525822e-05!GO:0030036;actin cytoskeleton organization and biogenesis;2.92242694195738e-05!GO:0017038;protein import;4.1523823097917e-05!GO:0006084;acetyl-CoA metabolic process;4.1523823097917e-05!GO:0006325;establishment and/or maintenance of chromatin architecture;5.37894957696074e-05!GO:0006888;ER to Golgi vesicle-mediated transport;5.37894957696074e-05!GO:0044453;nuclear membrane part;5.85299048406223e-05!GO:0051188;cofactor biosynthetic process;5.86272610282549e-05!GO:0043492;ATPase activity, coupled to movement of substances;5.90803645027232e-05!GO:0006752;group transfer coenzyme metabolic process;6.55246141448173e-05!GO:0051187;cofactor catabolic process;6.91943481026302e-05!GO:0005905;coated pit;8.056171842824e-05!GO:0042626;ATPase activity, coupled to transmembrane movement of substances;8.33836202145092e-05!GO:0030133;transport vesicle;0.000102512969640047!GO:0016772;transferase activity, transferring phosphorus-containing groups;0.000106846233600538!GO:0015931;nucleobase, nucleoside, nucleotide and nucleic acid transport;0.000109481942255451!GO:0048489;synaptic vesicle transport;0.000110696113567575!GO:0006259;DNA metabolic process;0.000110696113567575!GO:0005770;late endosome;0.000115082882640162!GO:0003676;nucleic acid binding;0.000115082882640162!GO:0016820;hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances;0.000119634169476659!GO:0030029;actin filament-based process;0.00014074494636301!GO:0051128;regulation of cellular component organization and biogenesis;0.000147341965994312!GO:0031202;RNA splicing factor activity, transesterification mechanism;0.00015842088085996!GO:0005769;early endosome;0.000161081127875069!GO:0006323;DNA packaging;0.000163376904228175!GO:0030425;dendrite;0.000203308380621136!GO:0051028;mRNA transport;0.000213354161578626!GO:0019226;transmission of nerve impulse;0.000221390759524753!GO:0016568;chromatin modification;0.000221634717641272!GO:0005813;centrosome;0.000226915777406397!GO:0003712;transcription cofactor activity;0.000306267830010507!GO:0003724;RNA helicase activity;0.000354408015068748!GO:0065002;intracellular protein transport across a membrane;0.000376034531732381!GO:0009108;coenzyme biosynthetic process;0.000410513477374223!GO:0033178;proton-transporting two-sector ATPase complex, catalytic domain;0.000414091023703089!GO:0055086;nucleobase, nucleoside and nucleotide metabolic process;0.000418506999636209!GO:0030118;clathrin coat;0.000424206164486157!GO:0007242;intracellular signaling cascade;0.000424471778044324!GO:0031072;heat shock protein binding;0.000453213587106715!GO:0030532;small nuclear ribonucleoprotein complex;0.000480105627710549!GO:0031252;leading edge;0.000533680747839842!GO:0004386;helicase activity;0.000544082399215899!GO:0007269;neurotransmitter secretion;0.000557489379660547!GO:0051087;chaperone binding;0.000578377036470384!GO:0006613;cotranslational protein targeting to membrane;0.000602605073024484!GO:0006897;endocytosis;0.000602605073024484!GO:0010324;membrane invagination;0.000602605073024484!GO:0016876;ligase activity, forming aminoacyl-tRNA and related compounds;0.000627888416373782!GO:0004812;aminoacyl-tRNA ligase activity;0.000627888416373782!GO:0016875;ligase activity, forming carbon-oxygen bonds;0.000627888416373782!GO:0051246;regulation of protein metabolic process;0.000644790342635929!GO:0003729;mRNA binding;0.000704240772344986!GO:0008026;ATP-dependent helicase activity;0.000722384531717782!GO:0000151;ubiquitin ligase complex;0.000722436430520151!GO:0016591;DNA-directed RNA polymerase II, holoenzyme;0.000844873771705296!GO:0043038;amino acid activation;0.000856352294411944!GO:0006418;tRNA aminoacylation for protein translation;0.000856352294411944!GO:0043039;tRNA aminoacylation;0.000856352294411944!GO:0009056;catabolic process;0.000904079196776532!GO:0030027;lamellipodium;0.000923938892433373!GO:0048523;negative regulation of cellular process;0.000924104476626587!GO:0043566;structure-specific DNA binding;0.000971014551486792!GO:0005815;microtubule organizing center;0.0010023658922093!GO:0042254;ribosome biogenesis and assembly;0.00103592515200714!GO:0007265;Ras protein signal transduction;0.0010512535375207!GO:0005741;mitochondrial outer membrane;0.0010574174836175!GO:0045261;proton-transporting ATP synthase complex, catalytic core F(1);0.00107559936659007!GO:0005875;microtubule associated complex;0.00108397117609348!GO:0019208;phosphatase regulator activity;0.00114862618315284!GO:0045786;negative regulation of progression through cell cycle;0.0011493737817754!GO:0051056;regulation of small GTPase mediated signal transduction;0.0011704949753864!GO:0000159;protein phosphatase type 2A complex;0.00118918056225856!GO:0016679;oxidoreductase activity, acting on diphenols and related substances as donors;0.0012171292352713!GO:0016681;oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor;0.0012171292352713!GO:0008121;ubiquinol-cytochrome-c reductase activity;0.0012171292352713!GO:0022406;membrane docking;0.00125628775170537!GO:0048278;vesicle docking;0.00125628775170537!GO:0007019;microtubule depolymerization;0.00129229208495291!GO:0016050;vesicle organization and biogenesis;0.00133099718814208!GO:0008601;protein phosphatase type 2A regulator activity;0.0013409418782316!GO:0005753;mitochondrial proton-transporting ATP synthase complex;0.00135700326729674!GO:0015980;energy derivation by oxidation of organic compounds;0.00144697887464545!GO:0006606;protein import into nucleus;0.00146318732882334!GO:0044432;endoplasmic reticulum part;0.00154335866938972!GO:0051170;nuclear import;0.00157671041294999!GO:0008021;synaptic vesicle;0.0015863531574717!GO:0003779;actin binding;0.00167795500066527!GO:0045055;regulated secretory pathway;0.00180250125088283!GO:0008047;enzyme activator activity;0.00185904433190909!GO:0009117;nucleotide metabolic process;0.00186618816849174!GO:0030427;site of polarized growth;0.00189506082654266!GO:0006904;vesicle docking during exocytosis;0.00190054129547012!GO:0007268;synaptic transmission;0.00190054129547012!GO:0016564;transcription repressor activity;0.00191590787833146!GO:0043623;cellular protein complex assembly;0.00196375667298741!GO:0046930;pore complex;0.00197556096363989!GO:0000902;cell morphogenesis;0.00210347456375677!GO:0032989;cellular structure morphogenesis;0.00210347456375677!GO:0006892;post-Golgi vesicle-mediated transport;0.00219493138034867!GO:0005096;GTPase activator activity;0.00227260005666389!GO:0016197;endosome transport;0.00235236190467722!GO:0006607;NLS-bearing substrate import into nucleus;0.00241934901998331!GO:0005938;cell cortex;0.00249487797347067!GO:0006414;translational elongation;0.00254705063617799!GO:0003697;single-stranded DNA binding;0.00262626579602271!GO:0030426;growth cone;0.00266997716932049!GO:0019867;outer membrane;0.00267029278842336!GO:0031968;organelle outer membrane;0.00267029278842336!GO:0051427;hormone receptor binding;0.0028120550526814!GO:0003755;peptidyl-prolyl cis-trans isomerase activity;0.00284190567160019!GO:0016301;kinase activity;0.00284190567160019!GO:0019888;protein phosphatase regulator activity;0.00291930229175756!GO:0031111;negative regulation of microtubule polymerization or depolymerization;0.00292084251771073!GO:0031124;mRNA 3'-end processing;0.00325171671279552!GO:0000314;organellar small ribosomal subunit;0.00337361874643598!GO:0005763;mitochondrial small ribosomal subunit;0.00337361874643598!GO:0006891;intra-Golgi vesicle-mediated transport;0.00341307555244948!GO:0012506;vesicle membrane;0.00341307555244948!GO:0005852;eukaryotic translation initiation factor 3 complex;0.00343747401999688!GO:0006650;glycerophospholipid metabolic process;0.00352733788096312!GO:0005048;signal sequence binding;0.0035423968341935!GO:0046488;phosphatidylinositol metabolic process;0.00354738440795713!GO:0048487;beta-tubulin binding;0.00354738440795713!GO:0031123;RNA 3'-end processing;0.00358969247151279!GO:0008654;phospholipid biosynthetic process;0.00361109333154291!GO:0001505;regulation of neurotransmitter levels;0.00374704708504382!GO:0008186;RNA-dependent ATPase activity;0.0039563249159146!GO:0006402;mRNA catabolic process;0.00424876177062437!GO:0031114;regulation of microtubule depolymerization;0.00425782465632348!GO:0007026;negative regulation of microtubule depolymerization;0.00425782465632348!GO:0005839;proteasome core complex (sensu Eukaryota);0.00425782465632348!GO:0007049;cell cycle;0.00436182102418363!GO:0016859;cis-trans isomerase activity;0.00444246337757954!GO:0005516;calmodulin binding;0.00446168373116276!GO:0006818;hydrogen transport;0.00448450018970652!GO:0006612;protein targeting to membrane;0.00474010475342457!GO:0004721;phosphoprotein phosphatase activity;0.00476449331137316!GO:0035257;nuclear hormone receptor binding;0.0048330637223826!GO:0051276;chromosome organization and biogenesis;0.00483565414324894!GO:0005793;ER-Golgi intermediate compartment;0.00493131371893409!GO:0048167;regulation of synaptic plasticity;0.00502772059512541!GO:0051540;metal cluster binding;0.00509926946696765!GO:0051536;iron-sulfur cluster binding;0.00509926946696765!GO:0035258;steroid hormone receptor binding;0.00512374162636156!GO:0016791;phosphoric monoester hydrolase activity;0.00515577510209236!GO:0007017;microtubule-based process;0.00528226850289969!GO:0005762;mitochondrial large ribosomal subunit;0.00528226850289969!GO:0000315;organellar large ribosomal subunit;0.00528226850289969!GO:0042175;nuclear envelope-endoplasmic reticulum network;0.00530549442003981!GO:0051168;nuclear export;0.00573352879009523!GO:0030658;transport vesicle membrane;0.00581066011623162!GO:0045263;proton-transporting ATP synthase complex, coupling factor F(o);0.00585379028727042!GO:0033177;proton-transporting two-sector ATPase complex, proton-transporting domain;0.00585379028727042!GO:0030054;cell junction;0.00604231929949056!GO:0015992;proton transport;0.00615621683390492!GO:0044448;cell cortex part;0.00619237995302992!GO:0004674;protein serine/threonine kinase activity;0.00619237995302992!GO:0000209;protein polyubiquitination;0.00623008649571104!GO:0005791;rough endoplasmic reticulum;0.00637510080638177!GO:0051129;negative regulation of cellular component organization and biogenesis;0.00647605707555355!GO:0009165;nucleotide biosynthetic process;0.00654729634215266!GO:0005789;endoplasmic reticulum membrane;0.00659198840929565!GO:0006399;tRNA metabolic process;0.00679466767192604!GO:0030867;rough endoplasmic reticulum membrane;0.00685337111032887!GO:0030660;Golgi-associated vesicle membrane;0.00696780722337688!GO:0005773;vacuole;0.00697533660212866!GO:0019902;phosphatase binding;0.0070595357461583!GO:0031901;early endosome membrane;0.00713065714191475!GO:0048519;negative regulation of biological process;0.00716267052470184!GO:0006890;retrograde vesicle-mediated transport, Golgi to ER;0.00737449071462881!GO:0008139;nuclear localization sequence binding;0.00752187614491052!GO:0030384;phosphoinositide metabolic process;0.00757530141998181!GO:0044456;synapse part;0.00766130110728609!GO:0008180;signalosome;0.00766130110728609!GO:0044433;cytoplasmic vesicle part;0.00795238294813556!GO:0046467;membrane lipid biosynthetic process;0.00801319622282079!GO:0005869;dynactin complex;0.00879916745693889!GO:0048500;signal recognition particle;0.00943432544574434!GO:0051726;regulation of cell cycle;0.00953557777198198!GO:0030865;cortical cytoskeleton organization and biogenesis;0.00966985481461607!GO:0050803;regulation of synapse structure and activity;0.0097070401884897!GO:0004004;ATP-dependent RNA helicase activity;0.00971943089473605!GO:0005838;proteasome regulatory particle (sensu Eukaryota);0.00982176160391766!GO:0043209;myelin sheath;0.0100205775069897!GO:0030320;cellular monovalent inorganic anion homeostasis;0.0100205775069897!GO:0055083;monovalent inorganic anion homeostasis;0.0100205775069897!GO:0055064;chloride ion homeostasis;0.0100205775069897!GO:0030644;cellular chloride ion homeostasis;0.0100205775069897!GO:0030530;heterogeneous nuclear ribonucleoprotein complex;0.0103154933101085!GO:0016311;dephosphorylation;0.0105500782278909!GO:0005085;guanyl-nucleotide exchange factor activity;0.0106271427162095!GO:0016281;eukaryotic translation initiation factor 4F complex;0.010775373859941!GO:0019887;protein kinase regulator activity;0.011011299246767!GO:0030258;lipid modification;0.0111232445573987!GO:0043021;ribonucleoprotein binding;0.0116060710540299!GO:0006333;chromatin assembly or disassembly;0.0118197856922404!GO:0001578;microtubule bundle formation;0.0118386620503054!GO:0004722;protein serine/threonine phosphatase activity;0.0119859692964576!GO:0016272;prefoldin complex;0.0120193994596088!GO:0050839;cell adhesion molecule binding;0.012022492032741!GO:0006974;response to DNA damage stimulus;0.0122161673136146!GO:0004298;threonine endopeptidase activity;0.0124874305029879!GO:0030424;axon;0.0124987487611608!GO:0030137;COPI-coated vesicle;0.0124987487611608!GO:0003713;transcription coactivator activity;0.0126420483551571!GO:0030742;GTP-dependent protein binding;0.0128592376368398!GO:0008154;actin polymerization and/or depolymerization;0.0130808082118021!GO:0046578;regulation of Ras protein signal transduction;0.0135385767316535!GO:0035035;histone acetyltransferase binding;0.013562165181438!GO:0016363;nuclear matrix;0.013562165181438!GO:0000074;regulation of progression through cell cycle;0.0137621768002217!GO:0043284;biopolymer biosynthetic process;0.0138028417326738!GO:0003746;translation elongation factor activity;0.0140258208166052!GO:0045187;regulation of circadian sleep/wake cycle, sleep;0.0140258208166052!GO:0004667;prostaglandin-D synthase activity;0.0140258208166052!GO:0050802;circadian sleep/wake cycle, sleep;0.0140258208166052!GO:0022410;circadian sleep/wake cycle process;0.0140258208166052!GO:0042749;regulation of circadian sleep/wake cycle;0.0140258208166052!GO:0050767;regulation of neurogenesis;0.0145349716340222!GO:0005868;cytoplasmic dynein complex;0.0145974283578027!GO:0006366;transcription from RNA polymerase II promoter;0.0147642305484321!GO:0007005;mitochondrion organization and biogenesis;0.0148948782626493!GO:0016773;phosphotransferase activity, alcohol group as acceptor;0.0149589921195942!GO:0003714;transcription corepressor activity;0.0150297480814238!GO:0051920;peroxiredoxin activity;0.015264345518959!GO:0007266;Rho protein signal transduction;0.0156580698317081!GO:0031371;ubiquitin conjugating enzyme complex;0.0157226776571169!GO:0008219;cell death;0.0157226776571169!GO:0016265;death;0.0157226776571169!GO:0006364;rRNA processing;0.0160772336721676!GO:0030132;clathrin coat of coated pit;0.0161011376657785!GO:0000059;protein import into nucleus, docking;0.0168351168261068!GO:0033673;negative regulation of kinase activity;0.0170100650521134!GO:0006469;negative regulation of protein kinase activity;0.0170100650521134!GO:0031109;microtubule polymerization or depolymerization;0.0177151452944181!GO:0004428;inositol or phosphatidylinositol kinase activity;0.0177737349468166!GO:0051261;protein depolymerization;0.0184281391534196!GO:0016740;transferase activity;0.0185881093358024!GO:0019207;kinase regulator activity;0.0186572011209933!GO:0051252;regulation of RNA metabolic process;0.0189284255113092!GO:0005786;signal recognition particle, endoplasmic reticulum targeting;0.0192015301664531!GO:0006614;SRP-dependent cotranslational protein targeting to membrane;0.0192015301664531!GO:0045047;protein targeting to ER;0.0192015301664531!GO:0060052;neurofilament cytoskeleton organization and biogenesis;0.0192486051046922!GO:0043681;protein import into mitochondrion;0.0192486051046922!GO:0046870;cadmium ion binding;0.0193384164008389!GO:0003690;double-stranded DNA binding;0.0193384164008389!GO:0030866;cortical actin cytoskeleton organization and biogenesis;0.0194913948293171!GO:0003711;transcription elongation regulator activity;0.0198610502183408!GO:0030659;cytoplasmic vesicle membrane;0.0205522421505194!GO:0008312;7S RNA binding;0.0207327760812026!GO:0005001;transmembrane receptor protein tyrosine phosphatase activity;0.0207433861615321!GO:0019198;transmembrane receptor protein phosphatase activity;0.0207433861615321!GO:0016079;synaptic vesicle exocytosis;0.0212766071064487!GO:0030041;actin filament polymerization;0.0216008613476669!GO:0051539;4 iron, 4 sulfur cluster binding;0.0216889872439152!GO:0030125;clathrin vesicle coat;0.0217187155454597!GO:0030665;clathrin coated vesicle membrane;0.0217187155454597!GO:0006470;protein amino acid dephosphorylation;0.0225899608798828!GO:0006916;anti-apoptosis;0.0226058239413429!GO:0005885;Arp2/3 protein complex;0.0229878769945266!GO:0050811;GABA receptor binding;0.0236054248857659!GO:0006383;transcription from RNA polymerase III promoter;0.0236708343182167!GO:0016072;rRNA metabolic process;0.0236956666482949!GO:0008022;protein C-terminus binding;0.0242183865180288!GO:0030119;AP-type membrane coat adaptor complex;0.0245656274689767!GO:0031902;late endosome membrane;0.0252693446935674!GO:0006091;generation of precursor metabolites and energy;0.0257039346659913!GO:0016676;oxidoreductase activity, acting on heme group of donors, oxygen as acceptor;0.0260934709769346!GO:0015002;heme-copper terminal oxidase activity;0.0260934709769346!GO:0016675;oxidoreductase activity, acting on heme group of donors;0.0260934709769346!GO:0004129;cytochrome-c oxidase activity;0.0260934709769346!GO:0043069;negative regulation of programmed cell death;0.0268195277638294!GO:0007034;vacuolar transport;0.0275235126106333!GO:0019903;protein phosphatase binding;0.0277029468708642!GO:0006378;mRNA polyadenylation;0.0288331578576729!GO:0019904;protein domain specific binding;0.0293723872301194!GO:0004437;inositol or phosphatidylinositol phosphatase activity;0.0293978345232811!GO:0030131;clathrin adaptor complex;0.029710760758696!GO:0043066;negative regulation of apoptosis;0.0297791694821729!GO:0012501;programmed cell death;0.0304394366494276!GO:0042026;protein refolding;0.0307903811442125!GO:0030663;COPI coated vesicle membrane;0.0311039999701422!GO:0030126;COPI vesicle coat;0.0311039999701422!GO:0006661;phosphatidylinositol biosynthetic process;0.0321290986384661!GO:0019894;kinesin binding;0.0322914481277333!GO:0006915;apoptosis;0.0323449405375799!GO:0045296;cadherin binding;0.0328354963601811!GO:0032011;ARF protein signal transduction;0.0329575251612422!GO:0032012;regulation of ARF protein signal transduction;0.0329575251612422!GO:0050789;regulation of biological process;0.0332118135469723!GO:0051287;NAD binding;0.0336950826187364!GO:0019783;small conjugating protein-specific protease activity;0.0339332135390545!GO:0051348;negative regulation of transferase activity;0.0346229402792604!GO:0030911;TPR domain binding;0.0362521254019268!GO:0006643;membrane lipid metabolic process;0.0366330515823714!GO:0007611;learning and/or memory;0.0385209835458921!GO:0000323;lytic vacuole;0.0389062117216507!GO:0005764;lysosome;0.0389062117216507!GO:0006376;mRNA splice site selection;0.0389127519200932!GO:0000389;nuclear mRNA 3'-splice site recognition;0.0389127519200932!GO:0005667;transcription factor complex;0.0394857189254047!GO:0019911;structural constituent of myelin sheath;0.0398658599894956!GO:0006665;sphingolipid metabolic process;0.0399452244098583!GO:0043631;RNA polyadenylation;0.0403703581353636!GO:0000062;acyl-CoA binding;0.0406834813098918!GO:0016579;protein deubiquitination;0.040689224385008!GO:0042670;retinal cone cell differentiation;0.0415868473183707!GO:0051281;positive regulation of release of sequestered calcium ion into cytosol;0.0415868473183707!GO:0046549;retinal cone cell development;0.0415868473183707!GO:0050794;regulation of cellular process;0.0419793211561797!GO:0009066;aspartate family amino acid metabolic process;0.0427119113511842!GO:0003725;double-stranded RNA binding;0.0431881555652983!GO:0006611;protein export from nucleus;0.0435429857424789!GO:0006100;tricarboxylic acid cycle intermediate metabolic process;0.0445834804702253!GO:0005100;Rho GTPase activator activity;0.0445834804702253!GO:0043025;cell soma;0.0445834804702253!GO:0043488;regulation of mRNA stability;0.0445834804702253!GO:0043487;regulation of RNA stability;0.0445834804702253!GO:0030134;ER to Golgi transport vesicle;0.0454274173695248!GO:0030880;RNA polymerase complex;0.0454910536293107!GO:0005955;calcineurin complex;0.0455028122491162!GO:0018065;protein-cofactor linkage;0.0462095998070392!GO:0005832;chaperonin-containing T-complex;0.0468728967458549!GO:0006281;DNA repair;0.0468728967458549!GO:0004843;ubiquitin-specific protease activity;0.0474905546809362!GO:0022402;cell cycle process;0.0477107593338908!GO:0022008;neurogenesis;0.0478345223563273!GO:0007030;Golgi organization and biogenesis;0.0481964231886596
|sample_id=10172
|sample_note=
|sample_sex=female
|sample_species=Human (Homo sapiens)
|sample_strain=
|sample_tissue=occipital cortex
|top_motifs=REST:3.77653850855;AHR_ARNT_ARNT2:3.75332144315;CUX2:3.71551026658;HOXA9_MEIS1:3.5186323938;MYFfamily:3.42285317772;NHLH1,2:3.33656701003;FOXM1:3.31749185884;PRDM1:3.23319140685;DBP:3.23085745141;ATF2:3.11147983255;PRRX1,2:3.06571500298;MTE{core}:3.0112181312;ZFP161:2.79723044406;NANOG:2.77345263337;MTF1:2.69747548001;PAX6:2.67279559414;NKX3-2:2.6302814921;RREB1:2.52017653735;SOX5:2.47197505874;GFI1B:2.45085224173;OCT4_SOX2{dimer}:2.40469586027;FOXQ1:2.38996244945;NFIX:2.38571906757;LMO2:2.37454741225;MED-1{core}:2.36220557208;NKX6-1,2:2.30032824568;ZBTB6:2.29891730556;MZF1:2.29191933386;GTF2I:2.23000331809;ALX1:2.21926476368;SOX2:2.16250634914;ESRRA:2.14890752194;POU6F1:2.14471139623;RFX1:2.12049049722;JUN:2.11815411654;BREu{core}:2.11312607137;ARID5B:2.10720193141;TGIF1:2.09597331282;EGR1..3:1.95839400081;PAX4:1.94517149795;SMAD1..7,9:1.89639407733;HIC1:1.86424485931;KLF4:1.81390827953;PAX5:1.77864814474;FOX{F1,F2,J1}:1.72243580975;NRF1:1.71816599419;XBP1:1.69807938459;GATA4:1.68623222786;LEF1_TCF7_TCF7L1,2:1.68386043794;SOX17:1.64467319264;NFIL3:1.64467295654;FOXP3:1.62666785879;NKX2-3_NKX2-5:1.57780465456;HOX{A4,D4}:1.53063055817;POU5F1:1.51237789353;TFAP2B:1.49459227109;HMGA1,2:1.41796945856;RFX2..5_RFXANK_RFXAP:1.27984056652;ZNF384:1.27462673445;HBP1_HMGB_SSRP1_UBTF:1.22495431397;IKZF2:1.19418209433;FOXN1:1.19252002846;PATZ1:1.19070257648;POU3F1..4:1.18664926015;GZF1:1.0985664897;TFDP1:0.978809049547;SOX{8,9,10}:0.961557299133;CREB1:0.937001226047;PDX1:0.926459736525;ZEB1:0.920903814141;BPTF:0.871087645766;LHX3,4:0.856108443728;CDC5L:0.819392007185;FOXD3:0.79112015476;MYOD1:0.772399849263;MAZ:0.768255989952;ZNF238:0.712994027833;ONECUT1,2:0.692472474235;YY1:0.686505142501;ZNF143:0.661916649965;RORA:0.659786976487;GTF2A1,2:0.649934528969;MEF2{A,B,C,D}:0.64787990553;EBF1:0.621445126298;RBPJ:0.616311784845;TLX2:0.582002645209;MAFB:0.496028412806;ATF5_CREB3:0.491636329865;ZNF423:0.467079950719;ZIC1..3:0.440347255444;CRX:0.429666773112;STAT2,4,6:0.427721579952;PBX1:0.412193006568;PAX8:0.408163984839;ATF4:0.403209529947;STAT1,3:0.402557687223;SREBF1,2:0.390464327269;TEF:0.366947222962;SPZ1:0.332693714931;AR:0.313850879893;GFI1:0.305387959975;NANOG{mouse}:0.295070088155;T:0.25963338934;POU1F1:0.256380312314;GCM1,2:0.239997234661;HMX1:0.237193362351;EP300:0.230199241832;NKX3-1:0.224218314148;HAND1,2:0.202407385782;UFEwm:0.167497102355;VSX1,2:0.107437779987;ZBTB16:0.0880654341799;FOX{D1,D2}:0.0864295144527;IRF7:0.0573244738917;PAX3,7:0.0187624573202;TFAP2{A,C}:0.00283410996215;CEBPA,B_DDIT3:-0.0163855905934;TOPORS:-0.0378768094689;FOXP1:-0.0575111367718;GATA6:-0.0625372797349;PAX1,9:-0.0934338124049;NR3C1:-0.150901730718;NFATC1..3:-0.180164598605;SNAI1..3:-0.188436199894;PAX2:-0.25807988529;NFE2L2:-0.26822933843;RXR{A,B,G}_{NR1H2,PPAR}dimers:-0.270779996829;NFE2:-0.281767427498;bHLH_family:-0.306281519791;NFY{A,B,C}:-0.319744200851;TBX4,5:-0.342259241894;TLX1..3_NFIC{dimer}:-0.361436683929;STAT5{A,B}:-0.363177592594;FOX{I1,J2}:-0.377513805209;NFE2L1:-0.385625529814;FOXL1:-0.419137318916;SPI1:-0.469577295769;DMAP1_NCOR{1,2}_SMARC:-0.487055216607;EVI1:-0.497680087218;FOXA2:-0.508774573827;HNF1A:-0.524380361025;SP1:-0.527489813281;ADNP_IRX_SIX_ZHX:-0.611373209833;NR5A1,2:-0.653446087408;MYBL2:-0.671470844169;IRF1,2:-0.688026368578;ATF6:-0.698286710893;IKZF1:-0.733133279141;NKX2-1,4:-0.736204986217;FOSL2:-0.746130932517;SPIB:-0.780221704335;BACH2:-0.797453100166;ESR1:-0.798771073652;HSF1,2:-0.819678704605;AIRE:-0.826511393571;FOXO1,3,4:-0.832072483453;FOS_FOS{B,L1}_JUN{B,D}:-0.864902067006;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:-0.882006218053;TAL1_TCF{3,4,12}:-0.890583019023;TEAD1:-0.953018697331;ETS1,2:-0.968203033994;TFAP4:-0.992608226732;HNF4A_NR2F1,2:-1.03116394957;HOX{A6,A7,B6,B7}:-1.04085220369;NFKB1_REL_RELA:-1.06619024925;HLF:-1.07774741933;HIF1A:-1.10324053312;CDX1,2,4:-1.10514034898;MYB:-1.14917421106;E2F1..5:-1.15121652205;PITX1..3:-1.18061254755;RUNX1..3:-1.2080732344;NKX2-2,8:-1.25775848023;ELK1,4_GABP{A,B1}:-1.30199482659;ALX4:-1.32925057142;GLI1..3:-1.35801606589;TP53:-1.38438364424;POU2F1..3:-1.39400892079;RXR{A,B,G}:-1.41017928817;NR1H4:-1.42067455005;RXRA_VDR{dimer}:-1.48187178295;SRF:-1.51597861206;TBP:-1.56921514892;ELF1,2,4:-1.60202135551;HOX{A5,B5}:-1.63535614218;HES1:-1.75986006462;ZNF148:-1.77977881711;XCPE1{core}:-1.92924850681;TFCP2:-1.97723245041;PPARG:-2.15795496345;EN1,2:-2.62747695611;NR6A1:-3.06681653925
|xref=
|zenbu_report=https://fantom.gsc.riken.jp/zenbu/reports/#miRNA_expression_atlas_human;search_select_hide=table111:FF:10172-103C1;search_select_hide=table117:FF:10172-103C1
}}
}}

Latest revision as of 12:24, 3 June 2020

Name:occipital cortex - adult, donor10196
Species:Human (Homo sapiens)
Library ID:CNhs13798
Sample type:tissues
Genomic View: UCSC
RefEX:Specific genes
FANTOM CAT:1, 2, 3, 4, 5, 6, 7
CAGEd-oPOSSUM:link
ZENBU report :link
Additional information
Sample information
strainNA
tissueoccipital cortex
dev stageNA
sexfemale
age60
cell typeCELL MIXTURE - tissue sample
cell lineNA
companyNA
collaborationPeter Heutink
External link for information[{{{sample_info_link}}} {{{sample_info_link}}}]
RNA information
lot numberNA
catalog numberNA
sample typetotal RNA
extraction protocol (Details)OP-RNA-extraction-totalRNA-miRNeasy_Mini-v1.0

CAGE Accession numbers
MethodSample accession id
CAGE  SAMD00005173
Library accession numbers

Library idMethodExp. accession idRun accession id
CNhs13798 CAGE DRX008690 DRR009562
Accession ID Hg19

Library idBAMCTSS
CNhs13798 DRZ000987 DRZ002372
Accession ID Hg38

Library idBAMCTSS
CNhs13798 DRZ012337 DRZ013722
Download raw sequence, BAM & CTSS
Hg19
FastaBAMCTSS
downloaddownloaddonwload
Hg38
BAMCTSS
downloaddonwload


Relative expression to median (log10)

Transcription factors with enriched expression in this sampleRanked list of transcription factor promoter expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed.



Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data

Coexpression clusterscore
C0-CD14-Eosinophils-Neutrophils-Basophils-CD34-immature-Peripheral0
C1-testis-epididymis-embryonic-medulla-pituitary-trachea-caudate0
C10-occipital-temporal-parietal-brain-duodenum-Neurons-Neural0.383
C100-rhabdomyosarcoma-gastric-pineal-Wilms-cervical-mesodermal-endometrial0
C101-small-cerebellum-maxillary-colon-parietal-epididymis-merkel0
C102-neuroblastoma-testicular-pituitary-carcinosarcoma-rectum-acantholytic-iPS0
C103-CD4-CD8-Natural-Peripheral-Whole-Neutrophils-Basophils0
C104-Mast-Basophils-immature-CD14-CD34-eye-Natural0
C105-heart-skeletal-occipital-hippocampus-acute-Sebocyte-penis0.674
C106-Hep2-epitheloid-placenta-cervical-rectal-anaplastic-glassy0
C107-Neutrophils-CD14-Eosinophils-Monocytederived-Whole-Peripheral-blood0
C108-breast-hepatoblastoma-MCF7-parotid-salivary-submaxillary-prostate0
C109-Reticulocytes-non-acute-Hodgkin-Burkitt-retinoblastoma-lymphoma-0.33
C11-cerebellum-medulla-pons-parietal-occipital-middle-medial0
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C92-CD14CD16-CD14-Eosinophils-Basophils-Neutrophils-Macrophage-Whole0
C93-chronic-acute-leukemia-acantholytic-medulloblastoma-testis-papillotubular0
C94-smallcell-adrenal-lung-nonsmall-small-somatostatinoma-teratocarcinoma0
C95-lung-aorta-trachea-penis-Alveolar-throat-endometrioid0
C96-non-acute-tonsil-spleen-Burkitt-lymphoma-appendix0
C97-small-smallcell-gastrointestinal-argyrophil-putamen-duodenum-brain0
C98-CD8-Natural-Basophils-blood-CD4-Peripheral-Whole0
C99-hairy-mycosis-submaxillary-salivary-cord-kidney-parotid0



Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data



TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample

JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs13798

Jaspar motifP-value
MA0002.20.114
MA0003.10.333
MA0004.10.329
MA0006.10.175
MA0007.10.254
MA0009.10.195
MA0014.10.601
MA0017.10.00304
MA0018.20.0509
MA0019.10.633
MA0024.10.686
MA0025.10.368
MA0027.10.805
MA0028.10.0379
MA0029.10.0636
MA0030.10.966
MA0031.10.729
MA0035.20.0423
MA0038.10.421
MA0039.20.0339
MA0040.10.939
MA0041.10.603
MA0042.10.798
MA0043.10.979
MA0046.10.0182
MA0047.20.0573
MA0048.10.0492
MA0050.12.6555e-4
MA0051.10.00437
MA0052.10.241
MA0055.12.56496e-4
MA0057.10.791
MA0058.10.28
MA0059.10.132
MA0060.10.899
MA0061.10.0116
MA0062.27.33473e-4
MA0065.20.00101
MA0066.10.0483
MA0067.10.751
MA0068.10.545
MA0069.10.282
MA0070.10.745
MA0071.10.00748
MA0072.10.439
MA0073.10.378
MA0074.10.171
MA0076.10.0795
MA0077.10.422
MA0078.10.791
MA0079.20.786
MA0080.21.67408e-8
MA0081.10.0362
MA0083.10.0149
MA0084.10.321
MA0087.10.661
MA0088.10.191
MA0090.10.36
MA0091.10.554
MA0092.10.348
MA0093.10.347
MA0099.21.16525e-16
MA0100.10.606
MA0101.10.00201
MA0102.20.0486
MA0103.10.374
MA0104.20.676
MA0105.10.0158
MA0106.10.0402
MA0107.10.00618
MA0108.20.207
MA0111.10.726
MA0112.20.00302
MA0113.10.373
MA0114.10.00162
MA0115.10.227
MA0116.10.0288
MA0117.10.942
MA0119.10.0866
MA0122.10.587
MA0124.10.841
MA0125.10.548
MA0131.10.647
MA0135.10.0251
MA0136.17.0423e-12
MA0137.20.696
MA0138.20.0555
MA0139.10.517
MA0140.10.0305
MA0141.10.0142
MA0142.10.445
MA0143.10.474
MA0144.10.728
MA0145.10.168
MA0146.10.0018
MA0147.10.535
MA0148.10.178
MA0149.10.055
MA0150.18.30165e-4
MA0152.10.502
MA0153.10.0562
MA0154.10.0824
MA0155.10.454
MA0156.18.22215e-9
MA0157.10.546
MA0159.10.0186
MA0160.10.0151
MA0162.10.159
MA0163.15.85521e-4
MA0164.10.8
MA0258.10.0134
MA0259.10.982



FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data

library id: CNhs13798

Novel motifP-value
10.101
100.0705
1000.275
1010.284
1020.995
1030.424
1040.207
1050.102
1060.0223
1070.0402
1080.957
1090.00185
110.0139
1100.0549
1110.306
1120.621
1130.538
1140.373
1150.972
1160.0917
1170.00636
1180.11
1190.274
120.462
1200.319
1210.425
1220.857
1230.743
1240.0021
1250.275
1260.0343
1270.534
1280.14
1290.845
131.40386e-4
1300.169
1310.0143
1320.685
1330.0294
1340.714
1350.0555
1362.14956e-4
1370.751
1380.91
1390.319
140.712
1400.541
1410.863
1420.831
1430.197
1440.994
1450.0423
1460.32
1470.514
1480.565
1490.405
150.157
1500.116
1510.7
1520.0401
1530.876
1540.417
1550.493
1560.619
1570.351
1580.249
1590.0421
160.0675
1600.365
1610.214
1620.729
1630.903
1640.0138
1650.07
1660.864
1670.908
1680.48
1690.0169
170.112
180.312
190.218
20.966
200.0666
210.0522
220.149
230.473
240.0332
250.457
267.47965e-6
270.793
280.638
290.0123
30.0442
300.893
310.989
320.0249
330.0749
340.527
350.933
360.276
370.0358
380.375
390.129
40.736
400.0399
410.574
420.306
430.109
440.241
450.654
460.112
470.0829
480.0502
490.232
50.992
500.11
510.592
520.543
530.987
540.411
550.624
560.437
570.406
580.518
590.0674
60.796
600.0548
610.0485
620.314
630.113
640.33
650.299
660.214
670.497
680.167
690.433
70.0338
700.141
710.0121
720.425
730.015
740.907
750.0413
760.364
770.147
780.00496
790.306
80.0589
800.868
810.666
820.805
830.0215
840.392
850.356
860.22
878.2408e-5
880.773
890.861
90.362
900.253
910.588
920.934
930.472
940.305
950.00584
960.847
970.619
980.46
990.566



de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br> library id: CNhs13798


FANTOM5 (FF) ontology

Direct parent terms


Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data

UBERON: Anatomy
0000468 (multi-cellular organism)
0007023 (adult organism)
0000955 (brain)
0002021 (occipital lobe)
0000956 (cerebral cortex)
0000479 (tissue)
0004121 (ectoderm-derived structure)
0000064 (organ part)
0010314 (structure with developmental contribution from neural crest)
0011216 (organ system subdivision)
0000062 (organ)
0000061 (anatomical structure)
0000465 (material anatomical entity)
0000481 (multi-tissue structure)
0000073 (regional part of nervous system)
0000477 (anatomical cluster)
0003528 (brain grey matter)
0002791 (regional part of telencephalon)
0000467 (anatomical system)
0002619 (regional part of cerebral cortex)
0001062 (anatomical entity)
0000480 (anatomical group)
0002616 (regional part of brain)
0002780 (regional part of forebrain)
0002020 (gray matter)
0010317 (germ layer / neural crest derived structure)
0001017 (central nervous system)
0001016 (nervous system)
0001869 (cerebral hemisphere)
0001893 (telencephalon)
0001890 (forebrain)
0000203 (pallium)
0001950 (neocortex)

FF: FANTOM5
0000102 (sample by type)
0000210 (human sample)
0000101 (sample by species)
0000001 (sample)
0000998 (adult tissue sample)
0000004 (tissue sample)
0010163 (occipital cortex - adult donor)

Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
UBERON:0002532 (epiblast (generic))
UBERON:0006601 (presumptive ectoderm)
UBERON:0010316 (germ layer / neural crest)

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