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{{Coexpression_clusters
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259.1;0.471671,MA0442.1;0}}
|full_id=C2883_carcinosarcoma_gastrointestinal_nonsmall_amygdala_frontal_occipital_pineal
|id=C2883
|ontology_enrichment_celltype=
|ontology_enrichment_disease=
|ontology_enrichment_uberon=UBERON:0001017!9.57e-54!82;UBERON:0000073!3.49e-53!94;UBERON:0001016!3.49e-53!94;UBERON:0005743!6.38e-53!86;UBERON:0001049!2.46e-49!57;UBERON:0005068!2.46e-49!57;UBERON:0006241!2.46e-49!57;UBERON:0007135!2.46e-49!57;UBERON:0002616!1.22e-47!59;UBERON:0000955!3.30e-47!69;UBERON:0006238!3.30e-47!69;UBERON:0002346!5.92e-43!90;UBERON:0003075!8.62e-42!86;UBERON:0007284!8.62e-42!86;UBERON:0000153!2.94e-40!129;UBERON:0007811!2.94e-40!129;UBERON:0000033!1.39e-39!123;UBERON:0000924!5.80e-38!173;UBERON:0006601!5.80e-38!173;UBERON:0002780!6.12e-38!41;UBERON:0001890!6.12e-38!41;UBERON:0006240!6.12e-38!41;UBERON:0003080!1.30e-36!42;UBERON:0004121!1.30e-36!169;UBERON:0002020!6.54e-32!34;UBERON:0003528!6.54e-32!34;UBERON:0001893!7.01e-32!34;UBERON:0002791!7.71e-31!33;UBERON:0001869!9.72e-31!32;UBERON:0003056!3.03e-30!61;UBERON:0000956!1.21e-24!25;UBERON:0000203!1.21e-24!25;UBERON:0002619!7.93e-24!22;UBERON:0007023!1.81e-23!115;UBERON:0001950!5.59e-22!20;UBERON:0003076!1.96e-13!15;UBERON:0003057!1.96e-13!15;UBERON:0000475!4.96e-13!365;UBERON:0004732!8.97e-12!13;UBERON:0004733!4.38e-11!12;UBERON:0002028!4.38e-11!12;UBERON:0007277!4.38e-11!12;UBERON:0001871!5.41e-09!7;UBERON:0002420!6.71e-09!9;UBERON:0007245!6.71e-09!9;UBERON:0010009!6.71e-09!9;UBERON:0010011!6.71e-09!9;UBERON:0000454!6.71e-09!9;UBERON:0000481!1.03e-08!347;UBERON:0000064!1.12e-08!219;UBERON:0002308!1.14e-08!9;UBERON:0000125!1.14e-08!9;UBERON:0000025!1.40e-08!194;UBERON:0002680!1.43e-08!9;UBERON:0001895!1.43e-08!9;UBERON:0010092!1.43e-08!9;UBERON:0000477!2.83e-08!286;UBERON:0000062!3.08e-08!511;UBERON:0000200!1.30e-07!6;UBERON:0001894!2.18e-07!7;UBERON:0006222!2.18e-07!7;UBERON:0004111!2.45e-07!241;UBERON:0000468!4.25e-07!659;UBERON:0009663!6.46e-07!7
}}

Latest revision as of 12:14, 17 September 2013


Full id: C2883_carcinosarcoma_gastrointestinal_nonsmall_amygdala_frontal_occipital_pineal



Phase1 CAGE Peaks

Hg19::chr7:145813151..145813164,+p14@CNTNAP2
Hg19::chr7:145813700..145813711,+p15@CNTNAP2
Hg19::chr7:145813717..145813743,+p5@CNTNAP2
Hg19::chr7:145813864..145813947,+p1@CNTNAP2


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data

No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
neural tube2.07e-7056
neural rod2.07e-7056
future spinal cord2.07e-7056
neural keel2.07e-7056
regional part of nervous system2.17e-6653
regional part of brain2.17e-6653
central nervous system1.54e-6581
nervous system5.22e-6389
brain1.50e-5868
future brain1.50e-5868
neural plate1.12e-5582
presumptive neural plate1.12e-5582
neurectoderm3.57e-5486
regional part of forebrain1.29e-5241
forebrain1.29e-5241
anterior neural tube1.29e-5241
future forebrain1.29e-5241
cerebral hemisphere3.07e-4332
ecto-epithelium4.61e-43104
telencephalon6.57e-4334
brain grey matter7.07e-4334
gray matter7.07e-4334
pre-chordal neural plate4.64e-4061
regional part of telencephalon4.90e-4032
ectoderm-derived structure7.44e-37171
ectoderm7.44e-37171
presumptive ectoderm7.44e-37171
structure with developmental contribution from neural crest4.74e-36132
regional part of cerebral cortex1.41e-3322
cerebral cortex1.67e-3325
pallium1.67e-3325
adult organism3.30e-32114
organ system subdivision1.13e-31223
neocortex9.73e-3120
posterior neural tube4.27e-1815
chordal neural plate4.27e-1815
segmental subdivision of nervous system1.44e-1513
tube6.94e-15192
anatomical cluster1.62e-14373
segmental subdivision of hindbrain2.04e-1412
hindbrain2.04e-1412
presumptive hindbrain2.04e-1412
organ part6.22e-12218
anatomical conduit3.28e-11240
basal ganglion4.99e-119
nuclear complex of neuraxis4.99e-119
aggregate regional part of brain4.99e-119
collection of basal ganglia4.99e-119
cerebral subcortex4.99e-119
gyrus5.05e-116
diencephalon6.29e-117
future diencephalon6.29e-117
multi-tissue structure7.85e-11342
neural nucleus1.01e-109
nucleus of brain1.01e-109
regional part of metencephalon1.72e-109
metencephalon1.72e-109
future metencephalon1.72e-109
brainstem5.20e-106
parietal lobe2.12e-095
occipital lobe2.72e-095
temporal lobe4.24e-096
limbic system4.59e-095
organ1.60e-08503
telencephalic nucleus4.92e-087
epithelium9.98e-08306
cell layer1.72e-07309
regional part of diencephalon2.36e-074
corpus striatum2.47e-074
striatum2.47e-074
ventral part of telencephalon2.47e-074
future corpus striatum2.47e-074
gland of diencephalon4.38e-074
neuroendocrine gland4.38e-074


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.720743
MA0004.10.71247
MA0006.10.532262
MA0007.10.6918
MA0009.11.20602
MA0014.10.0695829
MA0017.10.577281
MA0019.12.02743
MA0024.11.09684
MA0025.11.34373
MA0027.12.83281
MA0028.10.550763
MA0029.11.11704
MA0030.11.10506
MA0031.11.03735
MA0038.10.824639
MA0040.11.12314
MA0041.10.732902
MA0042.10.697662
MA0043.11.20635
MA0046.11.19471
MA0048.11.30988
MA0050.11.66718
MA0051.11.91805
MA0052.11.12718
MA0055.10.396851
MA0056.10
MA0057.12.77736
MA0058.10.605914
MA0059.10.604454
MA0060.10.393285
MA0061.10.360128
MA0063.10
MA0066.10.825101
MA0067.11.53181
MA0068.10.313194
MA0069.11.19071
MA0070.11.17908
MA0071.10.782546
MA0072.11.1744
MA0073.10.0343867
MA0074.10.819248
MA0076.10.623864
MA0077.11.16637
MA0078.10.926725
MA0081.11.4709
MA0083.11.21381
MA0084.11.72172
MA0087.11.17185
MA0088.10.182167
MA0089.10
MA0090.10.640115
MA0091.10.715356
MA0092.10.673508
MA0093.10.535768
MA0095.10
MA0098.10
MA0100.10.83965
MA0101.10.539569
MA0103.10.521546
MA0105.10.232357
MA0106.10.869173
MA0107.10.453492
MA0108.21.03412
MA0109.10
MA0111.10.655276
MA0113.10.886811
MA0114.10.447443
MA0115.11.45393
MA0116.10.457606
MA0117.11.24497
MA0119.10.586221
MA0122.11.27173
MA0124.11.41151
MA0125.11.32534
MA0130.10
MA0131.10.94608
MA0132.10
MA0133.10
MA0135.11.23748
MA0136.10.832277
MA0139.10.344952
MA0140.10.779643
MA0141.10.602484
MA0142.11.00381
MA0143.10.887001
MA0144.10.430413
MA0145.10.195821
MA0146.10.221129
MA0147.10.46175
MA0148.10.739888
MA0149.10.769072
MA0062.20.353589
MA0035.20.778873
MA0039.20.777367
MA0138.20.928035
MA0002.20.379056
MA0137.20.558189
MA0104.20.392359
MA0047.20.856092
MA0112.21.65877
MA0065.21.09513
MA0150.10.633493
MA0151.10
MA0152.10.78681
MA0153.11.30799
MA0154.10.229241
MA0155.10.533581
MA0156.10.560797
MA0157.10.97481
MA0158.10
MA0159.11.1691
MA0160.10.756582
MA0161.10
MA0162.10.640035
MA0163.10.0725493
MA0164.10.90014
MA0080.20.535868
MA0018.20.870662
MA0099.20.7872
MA0079.25.41326
MA0102.21.75932
MA0258.10.418966
MA0259.10.471671
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data

(#promoters = Number of promoters in this coexpression cluster that have ChIP signal of the TF)

TF#promotersEnrichmentp-valueq-value
REST#597837.237521537096020.004104697304192610.0195972791658318



Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data

This analysis result is provided for C0 - C305 clusters.

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