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Coexpression cluster:C1834

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Full id: C1834_brain_cerebellum_temporal_occipital_duodenum_parietal_Chondrocyte



Phase1 CAGE Peaks

Hg19::chr1:14925173..14925196,+p2@KAZN
Hg19::chr1:14925286..14925299,+p4@KAZN
Hg19::chr1:14925315..14925338,+p3@KAZN
Hg19::chr1:15214179..15214181,+p@chr1:15214179..15214181
+
Hg19::chr5:179636159..179636220,-p1@RASGEF1C


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>


Cell Type
Ontology termp-valuen
neural cell1.84e-0725
Uber Anatomy
Ontology termp-valuen
regional part of nervous system9.09e-4194
nervous system9.09e-4194
central nervous system2.99e-3982
neural tube5.70e-3657
neural rod5.70e-3657
future spinal cord5.70e-3657
neural keel5.70e-3657
neural plate1.18e-3586
presumptive neural plate1.18e-3586
neurectoderm3.87e-3590
brain5.30e-3269
future brain5.30e-3269
adult organism1.22e-31115
regional part of brain3.58e-3059
ectoderm5.16e-27173
presumptive ectoderm5.16e-27173
ectoderm-derived structure6.50e-27169
anterior neural tube1.46e-2642
regional part of forebrain2.90e-2641
forebrain2.90e-2641
future forebrain2.90e-2641
head6.63e-25123
anterior region of body8.75e-25129
craniocervical region8.75e-25129
pre-chordal neural plate1.62e-2461
telencephalon1.60e-2334
gray matter2.44e-2334
brain grey matter2.44e-2334
regional part of telencephalon7.50e-2333
cerebral hemisphere3.39e-2232
cerebral cortex1.65e-1725
pallium1.65e-1725
organism subdivision3.92e-16365
regional part of cerebral cortex7.27e-1622
neocortex1.09e-1420
multi-tissue structure1.83e-13347
organ2.46e-12511
embryo1.12e-11612
multi-cellular organism2.80e-11659
organ part6.33e-11219
tube1.69e-10194
posterior neural tube2.16e-1015
chordal neural plate2.16e-1015
anatomical group5.35e-10626
anatomical system7.72e-10625
anatomical cluster1.49e-09286
embryonic structure1.51e-09605
developing anatomical structure1.51e-09605
segmental subdivision of nervous system2.68e-0913
germ layer3.01e-09604
embryonic tissue3.01e-09604
presumptive structure3.01e-09604
epiblast (generic)3.01e-09604
anatomical conduit7.01e-09241
segmental subdivision of hindbrain1.35e-0812
hindbrain1.35e-0812
presumptive hindbrain1.35e-0812
epithelium1.47e-07309
basal ganglion2.17e-079
nuclear complex of neuraxis2.17e-079
aggregate regional part of brain2.17e-079
collection of basal ganglia2.17e-079
cerebral subcortex2.17e-079
cell layer2.75e-07312
nucleus of brain2.84e-079
neural nucleus2.84e-079
regional part of metencephalon9.88e-079
metencephalon9.88e-079
future metencephalon9.88e-079


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.