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Coexpression cluster:C1690

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Full id: C1690_occipital_parietal_medial_amygdala_middle_hippocampus_olfactory



Phase1 CAGE Peaks

Hg19::chr12:81992190..81992193,-p20@PPFIA2
Hg19::chr7:154862971..154862985,-p4@LOC100128264
Hg19::chr7:98460739..98460745,-p17@TMEM130
Hg19::chr8:104831554..104831555,+p37@RIMS2
Hg19::chr8:2883208..2883233,-p@chr8:2883208..2883233
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube3.20e-8557
neural rod3.20e-8557
future spinal cord3.20e-8557
neural keel3.20e-8557
regional part of brain1.37e-7159
regional part of forebrain2.07e-6841
forebrain2.07e-6841
future forebrain2.07e-6841
anterior neural tube1.53e-6642
brain1.91e-6469
future brain1.91e-6469
central nervous system1.53e-6282
gray matter1.30e-5834
brain grey matter1.30e-5834
telencephalon1.69e-5834
neural plate1.01e-5686
presumptive neural plate1.01e-5686
regional part of nervous system2.37e-5694
nervous system2.37e-5694
regional part of telencephalon2.42e-5633
neurectoderm5.58e-5690
cerebral hemisphere3.07e-5532
regional part of cerebral cortex3.96e-4722
pre-chordal neural plate6.84e-4561
adult organism9.84e-45115
neocortex1.17e-4220
cerebral cortex7.39e-4125
pallium7.39e-4125
head1.52e-33123
anterior region of body2.45e-31129
craniocervical region2.45e-31129
ectoderm1.81e-26173
presumptive ectoderm1.81e-26173
ectoderm-derived structure3.63e-26169
basal ganglion8.91e-209
nuclear complex of neuraxis8.91e-209
aggregate regional part of brain8.91e-209
collection of basal ganglia8.91e-209
cerebral subcortex8.91e-209
nucleus of brain5.17e-199
neural nucleus5.17e-199
tube6.37e-19194
posterior neural tube6.63e-1915
chordal neural plate6.63e-1915
telencephalic nucleus2.83e-157
gyrus5.88e-156
temporal lobe8.89e-157
anatomical conduit5.69e-14241
segmental subdivision of hindbrain9.92e-1412
hindbrain9.92e-1412
presumptive hindbrain9.92e-1412
limbic system1.13e-125
segmental subdivision of nervous system1.59e-1213
brainstem1.91e-128
parietal lobe2.48e-125
occipital lobe2.54e-125
epithelium2.16e-11309
cell layer3.88e-11312
diencephalon4.79e-117
future diencephalon4.79e-117
organ part2.47e-10219
anatomical cluster2.75e-10286
corpus striatum3.56e-104
striatum3.56e-104
ventral part of telencephalon3.56e-104
future corpus striatum3.56e-104
organism subdivision5.43e-09365
regional part of metencephalon1.13e-089
metencephalon1.13e-089
future metencephalon1.13e-089
middle temporal gyrus1.64e-083
caudate-putamen4.22e-083
dorsal striatum4.22e-083
pons2.80e-073
medulla oblongata3.33e-073
myelencephalon3.33e-073
future myelencephalon3.33e-073
spinal cord4.23e-073
brainstem nucleus5.70e-073


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.