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MCL coexpression mm9:287

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Phase1 CAGE Peaks

 Short description
Mm9::chr10:34020647..34020664,+p@chr10:34020647..34020664
+
Mm9::chr11:33743405..33743416,-p5@Kcnip1
Mm9::chr14:67423733..67423743,-p@chr14:67423733..67423743
-
Mm9::chr14:76956449..76956460,-p4@Serp2
Mm9::chr15:78549275..78549309,-p5@Elfn2
Mm9::chr17:24625616..24625627,+p5@Caskin1
Mm9::chr19:47327907..47327937,+p@chr19:47327907..47327937
+
Mm9::chr1:33964544..33964555,-p3@Bend6
Mm9::chr2:124962334..124962359,+p1@Ctxn2
Mm9::chr2:124962484..124962505,+p2@Ctxn2
Mm9::chr2:181041454..181041465,+p@chr2:181041454..181041465
+
Mm9::chr3:88552800..88552811,-p@chr3:88552800..88552811
-
Mm9::chr4:117521906..117521913,+p15@Slc6a9
Mm9::chr5:137729501..137729520,+p1@Ache
Mm9::chr6:114081223..114081240,+p1@Slc6a11
Mm9::chr6:114198039..114198052,+p@chr6:114198039..114198052
+
Mm9::chr6:114198085..114198112,+p@chr6:114198085..114198112
+
Mm9::chr6:114198155..114198168,+p@chr6:114198155..114198168
+
Mm9::chr6:114198339..114198355,+p@chr6:114198339..114198355
+
Mm9::chr6:114198370..114198396,+p@chr6:114198370..114198396
+
Mm9::chr6:91107077..91107093,+p6@Hdac11
Mm9::chr6:91793870..91793909,-p@chr6:91793870..91793909
-
Mm9::chr7:136400541..136400570,+p1@Ppapdc1a
Mm9::chr7:26460119..26460206,-p1@Tmem91
Mm9::chr7:53125597..53125608,-p@chr7:53125597..53125608
-
Mm9::chr7:58877497..58877512,+p3@Slc17a6
Mm9::chr8:33760116..33760119,-p@chr8:33760116..33760119
-
Mm9::chr8:81334120..81334134,-p6@Lsm6
Mm9::chrX:61750178..61750185,+p@chrX:61750178..61750185
+


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data

GO IDGO nameFDR corrected p-value
GO:0006836neurotransmitter transport0.000487893433099392
GO:0005283sodium:amino acid symporter activity0.000487893433099392
GO:0005342organic acid transmembrane transporter activity0.000487893433099392
GO:0005416cation:amino acid symporter activity0.000793169376948295
GO:0005328neurotransmitter:sodium symporter activity0.00238250463219786
GO:0005343organic acid:sodium symporter activity0.00238250463219786
GO:0005326neurotransmitter transporter activity0.00238250463219786
GO:0015179L-amino acid transmembrane transporter activity0.00277289081461163
GO:0005275amine transmembrane transporter activity0.00544349046617558
GO:0015171amino acid transmembrane transporter activity0.00549769167310049
GO:0015370solute:sodium symporter activity0.00617884339273634
GO:0015294solute:cation symporter activity0.0095865853648283
GO:0046943carboxylic acid transmembrane transporter activity0.00977373582424807
GO:0006581acetylcholine catabolic process0.00977373582424807
GO:0003990acetylcholinesterase activity0.00977373582424807
GO:0022891substrate-specific transmembrane transporter activity0.0124562618492223
GO:0008291acetylcholine metabolic process0.0154275641646028
GO:0032800receptor biosynthetic process0.0154275641646028
GO:0045212neurotransmitter receptor biosynthetic process0.0154275641646028
GO:0001505regulation of neurotransmitter levels0.0163882840827892
GO:0022857transmembrane transporter activity0.016420888300229
GO:0006810transport0.0169058882193297
GO:0051234establishment of localization0.0169058882193297
GO:0001919regulation of receptor recycling0.0169058882193297
GO:0043236laminin binding0.0169058882193297
GO:0005332gamma-aminobutyric acid:sodium symporter activity0.0169058882193297
GO:0022892substrate-specific transporter activity0.0178922045850977
GO:0031623receptor internalization0.0188998132089217
GO:0004104cholinesterase activity0.0188998132089217
GO:0042439ethanolamine and derivative metabolic process0.0188998132089217
GO:0015185L-gamma-aminobutyric acid transmembrane transporter activity0.0188998132089217
GO:0008324cation transmembrane transporter activity0.0200721206149368
GO:0001881receptor recycling0.0217456361305597
GO:0015293symporter activity0.0217456361305597
GO:0051179localization0.0219577964512983
GO:0050840extracellular matrix binding0.0219577964512983
GO:0043621protein self-association0.0219577964512983
GO:0045213neurotransmitter receptor metabolic process0.0219577964512983
GO:0005313L-glutamate transmembrane transporter activity0.0219577964512983
GO:0015172acidic amino acid transmembrane transporter activity0.0219577964512983
GO:0001504neurotransmitter uptake0.0249850850611956
GO:0051262protein tetramerization0.0278661202732491
GO:0015291secondary active transmembrane transporter activity0.0296954910337121
GO:0060041retina development in camera-type eye0.0299153999596034
GO:0042135neurotransmitter catabolic process0.0321993161904013
GO:0007268synaptic transmission0.0321993161904013
GO:0015075ion transmembrane transporter activity0.0323653279984625
GO:0004407histone deacetylase activity0.0357847268869069
GO:0033558protein deacetylase activity0.0357847268869069
GO:0019213deacetylase activity0.0394701876471836
GO:0042402biogenic amine catabolic process0.0394701876471836
GO:0019226transmission of nerve impulse0.0394701876471836
GO:0042219amino acid derivative catabolic process0.0432429813478802
GO:0006898receptor-mediated endocytosis0.0432429813478802



Relative expression of the co-expression cluster over median <br>Analyst:




Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br>cell_data<br>uberon_data<br><br>

Uber Anatomy
Ontology termp-valuen
regional part of nervous system2.49e-3954
neural tube1.98e-3652
neural rod1.98e-3652
future spinal cord1.98e-3652
neural keel1.98e-3652
neurectoderm9.42e-3564
neural plate9.42e-3564
presumptive neural plate9.42e-3564
central nervous system5.03e-3473
nervous system1.04e-3275
brain1.68e-2947
future brain1.68e-2947
gray matter6.16e-2934
ecto-epithelium1.12e-2873
ectoderm-derived structure1.20e-2895
ectoderm1.20e-2895
presumptive ectoderm1.20e-2895
regional part of brain2.65e-2846
pre-chordal neural plate2.97e-2649
anterior neural tube1.49e-2540
regional part of forebrain2.63e-2439
forebrain2.63e-2439
future forebrain2.63e-2439
brain grey matter3.72e-2229
regional part of telencephalon3.72e-2229
telencephalon3.72e-2229
structure with developmental contribution from neural crest8.15e-2092
cerebral cortex3.34e-1321
cerebral hemisphere3.34e-1321
pallium3.34e-1321
occipital lobe5.37e-1210
visual cortex5.37e-1210
neocortex5.37e-1210
regional part of cerebral cortex9.00e-1217
posterior neural tube5.22e-1112
chordal neural plate5.22e-1112
basal ganglion1.18e-108
nuclear complex of neuraxis1.18e-108
aggregate regional part of brain1.18e-108
collection of basal ganglia1.18e-108
cerebral subcortex1.18e-108
tube1.09e-09114
spinal cord1.72e-096
dorsal region element1.72e-096
dorsum1.72e-096
anatomical conduit2.66e-08122
regional part of spinal cord2.84e-085
gray matter of spinal cord2.84e-085
regional part of midbrain7.59e-074
midbrain7.59e-074
presumptive midbrain7.59e-074
midbrain neural tube7.59e-074


TFBS overrepresentation<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data

Novel motifs




JASPAR motifs


Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}

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