FF:10730-110B1: Difference between revisions
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|top_motifs= | |top_motifs=NKX2-3_NKX2-5:3.0629160625;HOX{A6,A7,B6,B7}:2.81448490467;ARID5B:2.6103218205;LMO2:2.4436012704;PBX1:2.26194124692;JUN:2.18148507942;GFI1:2.14427860033;PAX8:1.99375746373;NRF1:1.9542384212;DBP:1.82059430702;ONECUT1,2:1.81967028189;ESRRA:1.811208754;RXR{A,B,G}_{NR1H2,PPAR}dimers:1.71039856615;NFY{A,B,C}:1.70994822966;HAND1,2:1.65671808594;NR5A1,2:1.57510254382;ZEB1:1.54687596629;ELK1,4_GABP{A,B1}:1.54137769888;POU6F1:1.47788716487;SOX{8,9,10}:1.47601928256;ZNF143:1.45840316478;SNAI1..3:1.43440991675;NANOG:1.39932031849;RFX1:1.39363980576;PAX3,7:1.36352032969;ADNP_IRX_SIX_ZHX:1.30750748366;ALX1:1.28007280535;YY1:1.24392517599;ATF5_CREB3:1.18618112416;E2F1..5:1.16057491822;ARNT_ARNT2_BHLHB2_MAX_MYC_USF1:1.00946542812;PRRX1,2:0.978230830694;TGIF1:0.944268008608;FOXA2:0.944007589236;POU5F1:0.94073527611;FOX{I1,J2}:0.935259008293;MYOD1:0.928665865532;PDX1:0.92270073856;CUX2:0.914731458827;GFI1B:0.910971924837;LEF1_TCF7_TCF7L1,2:0.867387667124;ATF2:0.866388002515;RORA:0.852904227157;STAT1,3:0.837471111321;POU1F1:0.836288324817;NHLH1,2:0.825041568201;VSX1,2:0.809477912987;GATA6:0.800115793514;NFE2L2:0.737576824246;BREu{core}:0.708311581705;SOX17:0.700441497744;SOX2:0.698381851638;FOXQ1:0.688344954101;AHR_ARNT_ARNT2:0.669449799194;HOX{A4,D4}:0.657138287862;RFX2..5_RFXANK_RFXAP:0.656428271837;ZBTB6:0.631965165066;POU2F1..3:0.60136850691;MEF2{A,B,C,D}:0.596833041757;PAX6:0.596790860416;MYB:0.555420630889;NR3C1:0.548749648783;REST:0.530856619899;PAX5:0.508092121147;ZFP161:0.478380839348;PAX1,9:0.471213976882;FOX{F1,F2,J1}:0.445787230866;MED-1{core}:0.435863961929;MYFfamily:0.403369956016;FOX{D1,D2}:0.400332091721;XBP1:0.37732932935;GTF2I:0.372826555444;FOXL1:0.352231039861;ATF4:0.306130274697;NKX2-1,4:0.29170592608;MZF1:0.290974643164;OCT4_SOX2{dimer}:0.290210364678;NKX3-2:0.267920475489;NFE2:0.261823356924;PATZ1:0.251809332582;TEF:0.24863249092;ZIC1..3:0.235407538968;TBP:0.231741846205;TFAP2B:0.222348353883;TFDP1:0.174388681646;CRX:0.155759691182;NKX3-1:0.144333807691;ZNF423:0.138555210893;NKX6-1,2:0.12707856103;STAT5{A,B}:0.110579890502;CDC5L:0.107373558811;EGR1..3:0.0847101977856;CREB1:0.0782614023932;FOXN1:0.0758282708582;HLF:0.0650544516713;SREBF1,2:0.0448785624042;AR:0.0308430802251;SP1:0.00555698548342;FOSL2:-0.034103292247;HOX{A5,B5}:-0.0360821439306;ZNF148:-0.0716004443215;MTE{core}:-0.100298861469;MTF1:-0.121441313035;bHLH_family:-0.122679903421;NFIX:-0.139380990662;FOXD3:-0.148338853438;LHX3,4:-0.159174085224;TP53:-0.168368014929;HNF1A:-0.178606083373;CDX1,2,4:-0.192570648919;FOXM1:-0.248723371606;CEBPA,B_DDIT3:-0.298498078336;FOXP1:-0.300372402035;HIC1:-0.320668264812;MAZ:-0.32679035814;PAX4:-0.332372036425;BACH2:-0.335125168749;HSF1,2:-0.352535468345;RBPJ:-0.389528702809;HNF4A_NR2F1,2:-0.40015224369;AIRE:-0.416012034696;SOX5:-0.420283169286;ZBTB16:-0.430677280912;FOS_FOS{B,L1}_JUN{B,D}:-0.435253661585;PAX2:-0.437052744893;NANOG{mouse}:-0.44231376158;POU3F1..4:-0.442350793085;SPIB:-0.450042765224;MYBL2:-0.466307474941;DMAP1_NCOR{1,2}_SMARC:-0.466410523151;RREB1:-0.506311099102;KLF4:-0.506680664647;PITX1..3:-0.510252762298;GZF1:-0.520294065232;ATF6:-0.525662379419;HMGA1,2:-0.527368399169;MAFB:-0.550284381749;XCPE1{core}:-0.556092734426;HIF1A:-0.561306893726;NFKB1_REL_RELA:-0.600055945111;EVI1:-0.618629311037;TLX1..3_NFIC{dimer}:-0.631653455951;RUNX1..3:-0.647417312683;SPI1:-0.662891662325;EN1,2:-0.682326711522;NR6A1:-0.682956733679;FOXP3:-0.691488986965;TLX2:-0.69810899185;ELF1,2,4:-0.731751886258;TFAP4:-0.755556643553;TBX4,5:-0.764777129053;UFEwm:-0.800645008693;SMAD1..7,9:-0.800653679135;PRDM1:-0.806378807843;PPARG:-0.81088444462;NKX2-2,8:-0.838213606549;NFE2L1:-0.849745848367;IKZF1:-0.851531674111;T:-0.870998543906;HBP1_HMGB_SSRP1_UBTF:-0.891066828375;ETS1,2:-0.900729306776;HOXA9_MEIS1:-0.903015419107;STAT2,4,6:-0.909400788975;RXRA_VDR{dimer}:-0.91872589592;HES1:-0.932855413142;NFIL3:-0.943708453688;RXR{A,B,G}:-0.947017987361;EP300:-0.947841170496;HMX1:-0.984299392399;TFCP2:-1.00065255142;IKZF2:-1.00726960974;GCM1,2:-1.06746883014;ZNF238:-1.07196560607;ESR1:-1.07645408761;GTF2A1,2:-1.09279904714;NR1H4:-1.10089082424;TFAP2{A,C}:-1.14516716699;ZNF384:-1.22930935345;FOXO1,3,4:-1.24845920354;TAL1_TCF{3,4,12}:-1.27806448132;TEAD1:-1.3292766982;GATA4:-1.33689681694;GLI1..3:-1.38661340234;NFATC1..3:-1.39275052633;EBF1:-1.45431178612;IRF1,2:-1.47515075591;TOPORS:-1.47561873954;IRF7:-1.51726756887;BPTF:-1.60930882027;ALX4:-1.75623026437;SRF:-1.91550752204;SPZ1:-2.07047517234 | ||
|comment= | |comment= | ||
|created_by= | |created_by= | ||
Revision as of 18:03, 14 March 2012
| Name: | non-small cell lung cancer cell line:NCI-H1385 |
|---|---|
| Species: | Human (Homo sapiens) |
| Library ID: | {{{library_id}}} |
| Sample type: | {{{sample_category}}} |
| Genomic View: | UCSC |
| CAGEd-oPOSSUM: | link |
| Additional information | ||||||||||||||||||||||||||||
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Sample information
RNA information
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| Download raw sequence, BAM & CTSS | ||||||||||||
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Co-expression clusters with enriched expression in this sampleRanked list of co-expression cluster expression in this sample relative to the median expression in the FANTOM5 collection is shown. Value is log10 transformed. <br>Analyst:NA <br><br>link to dataset.<br>data
Repeat families with enriched expression in this sample<b>Summary:</b>Ranked list of repeat family expression in this sample relative tothe median expression in the FANTOM5 collection is shown. Value is log10transformed.<br><b>Analyst:</b>NA<br><br>link to dataset.<br>data
no result for this sample
TFBS(DNA)motifs over-represented in proximal region of promoters active in this sample
JASPAR motifs<b>Summary:</b>Association of JASPAR motif to the promoter expression in thissample. Pearson's correlation between the number of TFBSs estimated byusing the position-weight matrix for each promoter and its expression isexpressed as Z-score by taking the ones based on random position-weightmatrix, and the tail probability of the normal distribution correspondingto the Z-score is taken as the resulting P-value. Lower P-value indicatesmore (non-random) association of the motif to promoter expression<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12193
FANTOM5 phase1 novel unique motifs<b>Summary:</b>Association of the 169 novel and unique motifs discovered in FANTOM5 phase1 in this sample. Among the de-novo motifs discovered by DMF, HOMER,ChIPMunk, and ScanAll, only novel motifs are selected after comparison with known motif sets, and their clustering based on MACRO-APE resulted in169 novel and unique motifs. Their association to the promoter expression is evaluated in the same way to the JASPAR motif above<br><b>Analyst:</b> Michiel de Hoon <br><br><br>link to dataset.<br>data
library id: CNhs12193
| Novel motif | Logo | P-value |
|---|---|---|
| 1 | 1 | 0.237 |
| 10 | 10 | 0.154 |
| 100 | 100 | 0.425 |
| 101 | 101 | 0.491 |
| 102 | 102 | 0.27 |
| 103 | 103 | 0.444 |
| 104 | 104 | 0.684 |
| 105 | 105 | 0.518 |
| 106 | 106 | 6.41911e-5 |
| 107 | 107 | 0.0191 |
| 108 | 108 | 0.614 |
| 109 | 109 | 0.112 |
| 11 | 11 | 0.125 |
| 110 | 110 | 0.215 |
| 111 | 111 | 0.0317 |
| 112 | 112 | 0.116 |
| 113 | 113 | 0.64 |
| 114 | 114 | 0.0219 |
| 115 | 115 | 0.376 |
| 116 | 116 | 0.16 |
| 117 | 117 | 0.0579 |
| 118 | 118 | 0.322 |
| 119 | 119 | 0.169 |
| 12 | 12 | 0.962 |
| 120 | 120 | 0.739 |
| 121 | 121 | 0.994 |
| 122 | 122 | 0.184 |
| 123 | 123 | 0.15 |
| 124 | 124 | 0.572 |
| 125 | 125 | 0.9 |
| 126 | 126 | 0.1 |
| 127 | 127 | 0.567 |
| 128 | 128 | 0.0344 |
| 129 | 129 | 0.966 |
| 13 | 13 | 0.0391 |
| 130 | 130 | 0.316 |
| 131 | 131 | 0.775 |
| 132 | 132 | 0.567 |
| 133 | 133 | 0.199 |
| 134 | 134 | 0.468 |
| 135 | 135 | 0.724 |
| 136 | 136 | 0.493 |
| 137 | 137 | 0.0792 |
| 138 | 138 | 0.486 |
| 139 | 139 | 0.0146 |
| 14 | 14 | 0.611 |
| 140 | 140 | 0.685 |
| 141 | 141 | 0.98 |
| 142 | 142 | 0.945 |
| 143 | 143 | 0.429 |
| 144 | 144 | 0.256 |
| 145 | 145 | 0.0446 |
| 146 | 146 | 0.773 |
| 147 | 147 | 0.804 |
| 148 | 148 | 0.00247 |
| 149 | 149 | 0.0755 |
| 15 | 15 | 0.201 |
| 150 | 150 | 0.24 |
| 151 | 151 | 0.235 |
| 152 | 152 | 0.0232 |
| 153 | 153 | 0.223 |
| 154 | 154 | 0.79 |
| 155 | 155 | 0.893 |
| 156 | 156 | 0.742 |
| 157 | 157 | 0.79 |
| 158 | 158 | 0.905 |
| 159 | 159 | 0.294 |
| 16 | 16 | 0.143 |
| 160 | 160 | 0.155 |
| 161 | 161 | 0.595 |
| 162 | 162 | 0.19 |
| 163 | 163 | 0.695 |
| 164 | 164 | 0.0737 |
| 165 | 165 | 0.199 |
| 166 | 166 | 0.469 |
| 167 | 167 | 0.192 |
| 168 | 168 | 0.106 |
| 169 | 169 | 0.00308 |
| 17 | 17 | 0.219 |
| 18 | 18 | 0.32 |
| 19 | 19 | 0.0383 |
| 2 | 2 | 0.679 |
| 20 | 20 | 0.438 |
| 21 | 21 | 0.035 |
| 22 | 22 | 0.116 |
| 23 | 23 | 0.0315 |
| 24 | 24 | 0.485 |
| 25 | 25 | 0.945 |
| 26 | 26 | 0.0132 |
| 27 | 27 | 0.662 |
| 28 | 28 | 0.74 |
| 29 | 29 | 0.273 |
| 3 | 3 | 0.125 |
| 30 | 30 | 0.93 |
| 31 | 31 | 0.747 |
| 32 | 32 | 0.00325 |
| 33 | 33 | 0.428 |
| 34 | 34 | 0.232 |
| 35 | 35 | 0.544 |
| 36 | 36 | 0.703 |
| 37 | 37 | 0.159 |
| 38 | 38 | 0.383 |
| 39 | 39 | 0.0679 |
| 4 | 4 | 0.533 |
| 40 | 40 | 0.176 |
| 41 | 41 | 0.465 |
| 42 | 42 | 0.907 |
| 43 | 43 | 0.0623 |
| 44 | 44 | 0.678 |
| 45 | 45 | 0.654 |
| 46 | 46 | 0.297 |
| 47 | 47 | 0.637 |
| 48 | 48 | 0.296 |
| 49 | 49 | 0.203 |
| 5 | 5 | 0.318 |
| 50 | 50 | 0.0492 |
| 51 | 51 | 0.628 |
| 52 | 52 | 0.054 |
| 53 | 53 | 0.542 |
| 54 | 54 | 0.274 |
| 55 | 55 | 0.125 |
| 56 | 56 | 0.867 |
| 57 | 57 | 0.489 |
| 58 | 58 | 0.482 |
| 59 | 59 | 0.0435 |
| 6 | 6 | 0.736 |
| 60 | 60 | 0.00613 |
| 61 | 61 | 0.0482 |
| 62 | 62 | 0.227 |
| 63 | 63 | 0.0145 |
| 64 | 64 | 0.649 |
| 65 | 65 | 0.192 |
| 66 | 66 | 0.117 |
| 67 | 67 | 0.961 |
| 68 | 68 | 0.734 |
| 69 | 69 | 0.333 |
| 7 | 7 | 0.499 |
| 70 | 70 | 0.0589 |
| 71 | 71 | 0.107 |
| 72 | 72 | 0.206 |
| 73 | 73 | 0.0556 |
| 74 | 74 | 0.649 |
| 75 | 75 | 0.249 |
| 76 | 76 | 0.262 |
| 77 | 77 | 0.137 |
| 78 | 78 | 0.0365 |
| 79 | 79 | 0.0388 |
| 8 | 8 | 0.129 |
| 80 | 80 | 0.639 |
| 81 | 81 | 0.232 |
| 82 | 82 | 0.147 |
| 83 | 83 | 0.714 |
| 84 | 84 | 0.608 |
| 85 | 85 | 0.0772 |
| 86 | 86 | 0.417 |
| 87 | 87 | 0.777 |
| 88 | 88 | 0.724 |
| 89 | 89 | 0.699 |
| 9 | 9 | 0.291 |
| 90 | 90 | 0.138 |
| 91 | 91 | 0.157 |
| 92 | 92 | 0.313 |
| 93 | 93 | 0.161 |
| 94 | 94 | 0.355 |
| 95 | 95 | 0.996 |
| 96 | 96 | 0.954 |
| 97 | 97 | 0.679 |
| 98 | 98 | 0.799 |
| 99 | 99 | 0.712 |
de novo motifs identified by HOMER in promoters active in this sample<b>Summary:</b>The result of HOMER in this sample is shown.<br><b>Analyst:</b>NA <br>
library id: CNhs12193
FANTOM5 (FF) ontology
Direct parent terms
is_a relathionship
CL:0002553 lung fibroblast
EFO:0002091 biological replicate
FF:0000003 cell line sample
FF:0000210 human sample
FF:0102553 non-small cell lung cancer cell line sample
FF:0103764 NCI cell sample
Ancestor terms (non development)<b>Summary:</b>Connected ontology terms with is_a, part_of or located_in relationship <br><b>Analyst:</b> Hideya Kawaji<br><br>link to source data<br>data
CL: Cell type
0000000 (cell), 0000000 (cell)
0000003 (native cell)
0000034 (stem cell)
0000048 (multi fate stem cell)
0000055 (non-terminally differentiated cell)
0000057 (fibroblast)
0000066 (epithelial cell)
0000134 (mesenchymal cell)
0000219 (motile cell)
0000255 (eukaryotic cell)
0000548 (animal cell)
0000723 (somatic stem cell)
0002320 (connective tissue cell)
0002371 (somatic cell)
DOID: Disease
0050687 (cell type cancer)
1115 (sarcoma)
14566 (disease of cellular proliferation)
162 (cancer)
305 (carcinoma)
4 (disease)
7 (disease of anatomical entity)
UBERON: Anatomy
0000061 (anatomical structure)
0000062 (organ)
0000077 (mixed endoderm/mesoderm-derived structure)
0000118 (lung bud)
0000119 (cell layer)
0000170 (pair of lungs)
0000171 (respiration organ)
0000464 (anatomical space)
0000465 (material anatomical entity)
0000466 (immaterial anatomical entity)
0000467 (anatomical system)
0000468 (multi-cellular organism)
0000475 (organism subdivision)
0000477 (anatomical cluster)
0000479 (tissue)
0000480 (anatomical group)
0000481 (multi-tissue structure)
0000483 (epithelium)
0000915 (thoracic segment of trunk)
0000922 (embryo)
0000923 (germ layer)
0000925 (endoderm)
0000926 (mesoderm)
0001004 (respiratory system)
0001007 (digestive system)
0001041 (foregut)
0001048 (primordium)
0001062 (anatomical entity)
0001555 (digestive tract)
0002048 (lung)
0002050 (embryonic structure)
0002224 (thoracic cavity)
0002384 (connective tissue)
0002532 (epiblast (generic))
0003104 (mesenchyme)
0003258 (endoderm of foregut)
0004119 (endoderm-derived structure)
0004120 (mesoderm-derived structure)
0004185 (endodermal part of digestive tract)
0004921 (subdivision of digestive tract)
0005153 (epithelial bud)
0005178 (thoracic cavity element)
0005181 (thoracic segment organ)
0005423 (developing anatomical structure)
0005597 (lung primordium)
0005911 (endo-epithelium)
0007026 (primitive gut)
0008947 (respiratory primordium)
0009142 (entire embryonic mesenchyme)
FF: FANTOM5
NA
Ancestor terms (development)<b>Summary:</b>Connected ontology terms with develops_from, derives_from or preceded_by relationship <br><b>Analyst:</b> Hideya Kawaji <br><br>link to source data<br>data
NA
