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Coexpression cluster:C1690

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Full id: C1690_occipital_parietal_medial_amygdala_middle_hippocampus_olfactory



Phase1 CAGE Peaks

Hg19::chr12:81992190..81992193,-p20@PPFIA2
Hg19::chr7:154862971..154862985,-p4@LOC100128264
Hg19::chr7:98460739..98460745,-p17@TMEM130
Hg19::chr8:104831554..104831555,+p37@RIMS2
Hg19::chr8:2883208..2883233,-p@chr8:2883208..2883233
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of cerebral cortex1.23e-10922
cerebral hemisphere8.76e-10832
telencephalon2.40e-10134
regional part of telencephalon3.53e-9932
neocortex4.20e-9820
cerebral cortex1.71e-9625
pallium1.71e-9625
brain grey matter3.07e-9334
gray matter3.07e-9334
regional part of forebrain1.49e-9041
forebrain1.49e-9041
anterior neural tube1.49e-9041
future forebrain1.49e-9041
neural tube8.64e-8856
neural rod8.64e-8856
future spinal cord8.64e-8856
neural keel8.64e-8856
regional part of nervous system9.38e-8753
regional part of brain9.38e-8753
brain1.03e-7068
future brain1.03e-7068
central nervous system2.02e-6781
nervous system2.76e-6089
pre-chordal neural plate1.03e-5961
neural plate1.35e-5882
presumptive neural plate1.35e-5882
neurectoderm1.18e-5586
ecto-epithelium3.58e-45104
adult organism2.66e-41114
structure with developmental contribution from neural crest3.55e-37132
gyrus1.68e-356
limbic system1.48e-305
parietal lobe1.21e-295
occipital lobe2.47e-295
ectoderm-derived structure3.21e-29171
ectoderm3.21e-29171
presumptive ectoderm3.21e-29171
organ system subdivision1.74e-24223
tube5.02e-22192
temporal lobe8.66e-226
frontal cortex2.37e-183
basal ganglion5.41e-179
nuclear complex of neuraxis5.41e-179
aggregate regional part of brain5.41e-179
collection of basal ganglia5.41e-179
cerebral subcortex5.41e-179
anatomical conduit1.67e-16240
organ part7.96e-16218
corpus striatum2.72e-144
striatum2.72e-144
ventral part of telencephalon2.72e-144
future corpus striatum2.72e-144
amygdala1.22e-132
middle temporal gyrus2.40e-132
middle frontal gyrus3.90e-132
Ammon's horn4.15e-132
lobe parts of cerebral cortex4.15e-132
hippocampal formation4.15e-132
limbic lobe4.15e-132
anatomical cluster2.21e-12373
epithelium1.03e-11306
cell layer1.53e-11309
multi-tissue structure7.53e-11342
caudate-putamen3.92e-093
dorsal striatum3.92e-093
telencephalic nucleus2.27e-087
putamen1.63e-071
olfactory region2.37e-071
primary subdivision of skull2.37e-071
cranium2.37e-071
neurocranium2.37e-071
chondrocranium2.37e-071
cartilaginous neurocranium2.37e-071
head paraxial mesoderm2.37e-071
nucleus accumbens2.52e-071
ventral striatum2.52e-071
paracentral gyrus3.41e-071
insula3.85e-071
postcentral gyrus4.60e-071
occipital pole6.97e-071
pole of cerebral hemisphere6.97e-071
organ7.88e-07503


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.10.0497246
MA0004.10.626788
MA0006.10.452993
MA0007.10.606704
MA0009.11.11255
MA0014.10.161847
MA0017.10.496101
MA0019.10.784036
MA0024.11.00439
MA0025.11.24931
MA0027.12.73598
MA0028.10.470679
MA0029.11.02437
MA0030.11.01252
MA0031.10.945567
MA0038.10.736268
MA0040.11.03042
MA0041.10.64667
MA0042.10.612397
MA0043.11.11288
MA0046.11.10134
MA0048.10.195817
MA0050.10.613347
MA0051.10.731787
MA0052.11.03442
MA0055.10.0853006
MA0056.10
MA0057.10.189508
MA0058.11.29981
MA0059.11.29682
MA0060.10.321781
MA0061.11.44118
MA0063.10
MA0066.10.736721
MA0067.11.43651
MA0068.10.247962
MA0069.11.09737
MA0070.11.08584
MA0071.10.695094
MA0072.11.0812
MA0073.10.00220137
MA0074.10.730989
MA0076.10.540943
MA0077.11.07324
MA0078.10.836493
MA0081.10.522409
MA0083.11.12028
MA0084.11.62584
MA0087.11.07867
MA0088.10.132006
MA0089.10
MA0090.10.556637
MA0091.10.629594
MA0092.10.588959
MA0093.11.15584
MA0095.10
MA0098.10
MA0100.10.750974
MA0101.12.02769
MA0103.10.442769
MA0105.11.00065
MA0106.10.779931
MA0107.12.62998
MA0108.20.94238
MA0109.10
MA0111.10.5713
MA0113.10.797251
MA0114.10.372523
MA0115.11.35895
MA0116.10.382106
MA0117.11.1512
MA0119.10.504689
MA0122.11.17777
MA0124.11.31673
MA0125.11.23103
MA0130.10
MA0131.10.855546
MA0132.10
MA0133.10
MA0135.11.14377
MA0136.10.743749
MA0139.10.277033
MA0140.10.692258
MA0141.10.520334
MA0142.10.912455
MA0143.10.797437
MA0144.10.356507
MA0145.10.143698
MA0146.10.143081
MA0147.11.00307
MA0148.10.653474
MA0149.10.681935
MA0062.20.284987
MA0035.20.691506
MA0039.20.0118463
MA0138.20.837782
MA0002.20.30855
MA0137.20.47779
MA0104.20.320919
MA0047.20.767096
MA0112.20.425004
MA0065.20.146576
MA0150.10.550239
MA0151.10
MA0152.10.69926
MA0153.11.21379
MA0154.10.172764
MA0155.10.130813
MA0156.10.480289
MA0157.10.883854
MA0158.10
MA0159.10.386729
MA0160.10.669748
MA0161.10
MA0162.10.0592265
MA0163.10.0439995
MA0164.10.810347
MA0080.20.456437
MA0018.20.781393
MA0099.20.699641
MA0079.23.83292e-05
MA0102.21.66336
MA0258.10.345771
MA0259.11.02361
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.