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Coexpression cluster:C1690

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Full id: C1690_occipital_parietal_medial_amygdala_middle_hippocampus_olfactory



Phase1 CAGE Peaks

Hg19::chr12:81992190..81992193,-p20@PPFIA2
Hg19::chr7:154862971..154862985,-p4@LOC100128264
Hg19::chr7:98460739..98460745,-p17@TMEM130
Hg19::chr8:104831554..104831555,+p37@RIMS2
Hg19::chr8:2883208..2883233,-p@chr8:2883208..2883233
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Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
regional part of cerebral cortex1.23e-10922
cerebral hemisphere8.76e-10832
telencephalon2.40e-10134
regional part of telencephalon3.53e-9932
neocortex4.20e-9820
cerebral cortex1.71e-9625
pallium1.71e-9625
brain grey matter3.07e-9334
gray matter3.07e-9334
regional part of forebrain1.49e-9041
forebrain1.49e-9041
anterior neural tube1.49e-9041
future forebrain1.49e-9041
neural tube8.64e-8856
neural rod8.64e-8856
future spinal cord8.64e-8856
neural keel8.64e-8856
regional part of nervous system9.38e-8753
regional part of brain9.38e-8753
brain1.03e-7068
future brain1.03e-7068
central nervous system2.02e-6781
nervous system2.76e-6089
pre-chordal neural plate1.03e-5961
neural plate1.35e-5882
presumptive neural plate1.35e-5882
neurectoderm1.18e-5586
ecto-epithelium3.58e-45104
adult organism2.66e-41114
structure with developmental contribution from neural crest3.55e-37132
gyrus1.68e-356
limbic system1.48e-305
parietal lobe1.21e-295
occipital lobe2.47e-295
ectoderm-derived structure3.21e-29171
ectoderm3.21e-29171
presumptive ectoderm3.21e-29171
organ system subdivision1.74e-24223
tube5.02e-22192
temporal lobe8.66e-226
frontal cortex2.37e-183
basal ganglion5.41e-179
nuclear complex of neuraxis5.41e-179
aggregate regional part of brain5.41e-179
collection of basal ganglia5.41e-179
cerebral subcortex5.41e-179
anatomical conduit1.67e-16240
organ part7.96e-16218
corpus striatum2.72e-144
striatum2.72e-144
ventral part of telencephalon2.72e-144
future corpus striatum2.72e-144
amygdala1.22e-132
middle temporal gyrus2.40e-132
middle frontal gyrus3.90e-132
Ammon's horn4.15e-132
lobe parts of cerebral cortex4.15e-132
hippocampal formation4.15e-132
limbic lobe4.15e-132
anatomical cluster2.21e-12373
epithelium1.03e-11306
cell layer1.53e-11309
multi-tissue structure7.53e-11342
caudate-putamen3.92e-093
dorsal striatum3.92e-093
telencephalic nucleus2.27e-087
putamen1.63e-071
olfactory region2.37e-071
primary subdivision of skull2.37e-071
cranium2.37e-071
neurocranium2.37e-071
chondrocranium2.37e-071
cartilaginous neurocranium2.37e-071
head paraxial mesoderm2.37e-071
nucleus accumbens2.52e-071
ventral striatum2.52e-071
paracentral gyrus3.41e-071
insula3.85e-071
postcentral gyrus4.60e-071
occipital pole6.97e-071
pole of cerebral hemisphere6.97e-071
organ7.88e-07503


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)

{{{tfbs_overrepresentation_jaspar}}}



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.