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Coexpression cluster:C372

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Full id: C372_spinal_medulla_substantia_locus_thalamus_corpus_globus



Phase1 CAGE Peaks

Hg19::chr10:130489605..130489614,-p@chr10:130489605..130489614
-
Hg19::chr10:130489635..130489656,-p@chr10:130489635..130489656
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Hg19::chr10:14066483..14066492,-p@chr10:14066483..14066492
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Hg19::chr10:6425090..6425094,-p@chr10:6425090..6425094
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Hg19::chr10:66295438..66295453,+p@chr10:66295438..66295453
+
Hg19::chr11:114146042..114146050,-p@chr11:114146042..114146050
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Hg19::chr11:65207271..65207286,+p9@AK129631
Hg19::chr11:81982984..81982991,+p@chr11:81982984..81982991
+
Hg19::chr13:34922094..34922105,+p@chr13:34922094..34922105
+
Hg19::chr17:42984508..42984535,-p8@GFAP
Hg19::chr17:42993715..42993719,-p@chr17:42993715..42993719
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Hg19::chr17:42993904..42993912,-p@chr17:42993904..42993912
-
Hg19::chr17:42994283..42994286,-p@chr17:42994283..42994286
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Hg19::chr18:24445821..24445829,+p@chr18:24445821..24445829
+
Hg19::chr18:74690849..74690860,-p@chr18:74690849..74690860
-
Hg19::chr1:95332264..95332266,+p@chr1:95332264..95332266
+
Hg19::chr2:20665905..20665909,-p@chr2:20665905..20665909
-
Hg19::chr3:16215714..16215728,+p9@GALNTL2
Hg19::chr3:16215730..16215743,+p3@GALNTL2
Hg19::chr3:16215758..16215779,+p8@GALNTL2
Hg19::chr4:67195068..67195099,-p@chr4:67195068..67195099
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Hg19::chr5:132113658..132113680,-p10@SEPT8
Hg19::chr5:132115740..132115752,-p@chr5:132115740..132115752
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Hg19::chr5:72570629..72570651,-p@chr5:72570629..72570651
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Hg19::chr5:72570665..72570692,-p@chr5:72570665..72570692
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Hg19::chr7:44145241..44145259,+p@chr7:44145241..44145259
+
Hg19::chr7:73779766..73779773,-p@chr7:73779766..73779773
-
Hg19::chr8:27522642..27522647,+p@chr8:27522642..27522647
+
Hg19::chr9:132312044..132312058,-p@chr9:132312044..132312058
-


Enriched pathways on this co-expression cluster<b>Summary:</b><br>Canonical pathway gene sets were compiled from Reactome, Wikipathways and KEGG. For the major signaling pathways, the transcriptionally-regulated genes (downstream targets) were obtained from Netpath. Combined, the canonical pathways and downstream targets totaled 489 human gene sets. The corresponding M. musculus gene sets were inferred by homology using the HomoloGene database. Enrichment for each of the canonical 489 pathways and gene sets included in the co-expression cluster was assessed by the hypergeometric probability. The resulting P values were also then adjusted by the Benjamini-Hochberg method for multiple comparisons.<br><b>Analyst: </b>Emmanuel Dimont<br><br>link to source dataset<br>data


No results for this coexpression

Enriched Gene Ontology terms on this co-expression cluster<b>Summary:</b> Results for GOStat analysis on co-expressed clusters. Each cluster with promoters mapping to at least two different genes was analysed with GOStat (PMID: 14962934) with default parameter. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br>data


No GOStat results

Enriched sample ontology terms on this co-expression cluster<b>Summary:</b>To summarize promoter activities (expression profile of a TSS region) across ~1000 samples, we performed enrichment analysis based on FANTOM5 Sample Ontology (FF ontology). The question here is “in which type of samples the promoter is more active”. To answer this question, we compared expressions (TPMs) in the samples associated with a sample ontology term and the rest of the samples by using the Mann-Whitney rank sum test. To summarize ontologies enriched in this co-expression cluster, we ran the same analysis on an averaged expression profile of all promoters that make up. <b>Analyst:</b> Hideya Kawaji <br><br>links to source dataset<br><br><br>uberon_data<br><br>


Uber Anatomy
Ontology termp-valuen
neural tube4.32e-10456
neural rod4.32e-10456
future spinal cord4.32e-10456
neural keel4.32e-10456
regional part of nervous system3.40e-8953
regional part of brain3.40e-8953
central nervous system1.55e-7481
brain1.25e-7268
future brain1.25e-7268
neural plate7.67e-7082
presumptive neural plate7.67e-7082
nervous system1.00e-6689
neurectoderm2.18e-6686
regional part of forebrain1.14e-6441
forebrain1.14e-6441
anterior neural tube1.14e-6441
future forebrain1.14e-6441
brain grey matter5.82e-5834
gray matter5.82e-5834
telencephalon1.12e-5734
ecto-epithelium4.30e-54104
regional part of telencephalon1.03e-4832
cerebral hemisphere1.80e-4832
adult organism5.49e-46114
pre-chordal neural plate2.18e-4261
structure with developmental contribution from neural crest1.43e-41132
posterior neural tube2.59e-4015
chordal neural plate2.59e-4015
brainstem9.59e-386
regional part of cerebral cortex9.11e-3522
neural nucleus8.16e-339
nucleus of brain8.16e-339
ectoderm-derived structure9.87e-33171
ectoderm9.87e-33171
presumptive ectoderm9.87e-33171
neocortex5.67e-3220
cerebral cortex1.70e-3025
pallium1.70e-3025
tube6.07e-27192
segmental subdivision of hindbrain7.34e-2512
hindbrain7.34e-2512
presumptive hindbrain7.34e-2512
basal ganglion5.81e-249
nuclear complex of neuraxis5.81e-249
aggregate regional part of brain5.81e-249
collection of basal ganglia5.81e-249
cerebral subcortex5.81e-249
organ system subdivision8.52e-24223
segmental subdivision of nervous system6.95e-2313
telencephalic nucleus1.01e-217
anatomical conduit1.82e-20240
medulla oblongata4.48e-203
myelencephalon4.48e-203
future myelencephalon4.48e-203
spinal cord7.42e-203
dorsal region element7.42e-203
dorsum7.42e-203
pons1.78e-193
gyrus3.71e-166
epithelium7.60e-15306
cell layer1.20e-14309
corpus striatum5.18e-144
striatum5.18e-144
ventral part of telencephalon5.18e-144
future corpus striatum5.18e-144
locus ceruleus9.74e-142
brainstem nucleus9.74e-142
hindbrain nucleus9.74e-142
dorsal plus ventral thalamus1.33e-132
thalamic complex1.33e-132
organ part2.56e-12218
anatomical cluster4.66e-12373
limbic system1.67e-115
regional part of metencephalon3.58e-119
metencephalon3.58e-119
future metencephalon3.58e-119
parietal lobe3.67e-115
multi-tissue structure1.99e-09342
caudate-putamen5.97e-093
dorsal striatum5.97e-093
frontal cortex7.01e-093
diencephalon1.57e-087
future diencephalon1.57e-087
temporal lobe2.96e-086
substantia nigra9.71e-081
midbrain nucleus9.71e-081
regional part of midbrain9.71e-081
midbrain9.71e-081
presumptive midbrain9.71e-081
midbrain neural tube9.71e-081
corpus callosum1.25e-071
central nervous system cell part cluster1.25e-071
axon tract1.25e-071
intercerebral commissure1.25e-071
dorsal telencephalic commissure1.25e-071
brain white matter1.25e-071
brain commissure1.25e-071
white matter1.25e-071
nervous system commissure1.25e-071
cerebral hemisphere white matter1.25e-071


Overrepresented TFBS (DNA) motifs on this co-expression cluster<b>Summary:</b>The values shown are the p-values for overrepresentation of the motif in this coexpression cluster. So a small p-value means a strong overrepresentation. <b>Analyst:</b> Michiel de Hoon <br><br>link to source data <br> Novel motifs <br>data <br><br> Jaspar motifs <br>data


Novel motifs



JASPAR motifs

Motifs-log10(p-value)
MA0003.12.59914e-05
MA0004.10.334532
MA0006.10.0364375
MA0007.10.309412
MA0009.10.429031
MA0014.10.00266684
MA0017.10.414482
MA0019.10.188957
MA0024.10.343215
MA0025.10.544326
MA0027.11.97447
MA0028.10.04151
MA0029.10.358654
MA0030.12.49242
MA0031.11.47015
MA0038.10.937891
MA0040.10.953232
MA0041.11.75008
MA0042.11.60229
MA0043.10.429296
MA0046.10.419892
MA0048.10.00844313
MA0050.10.31764
MA0051.10.157595
MA0052.10.366488
MA0055.10.108027
MA0056.10
MA0057.10.0271819
MA0058.10.0589349
MA0059.10.806387
MA0060.10.286154
MA0061.10.395971
MA0063.10
MA0066.10.160456
MA0067.10.711124
MA0068.10.0207462
MA0069.10.416668
MA0070.10.407339
MA0071.10.42511
MA0072.10.403605
MA0073.16.15363e-06
MA0074.10.157134
MA0076.10.065346
MA0077.10.397221
MA0078.10.633683
MA0081.10.0584929
MA0083.11.11054
MA0084.10.887042
MA0087.10.401577
MA0088.10.182269
MA0089.10
MA0090.10.533979
MA0091.11.67616
MA0092.10.601706
MA0093.10.341935
MA0095.10
MA0098.10
MA0100.10.168841
MA0101.10.348346
MA0103.10.135646
MA0105.10.117193
MA0106.10.547251
MA0107.10.414244
MA0108.20.296685
MA0109.10
MA0111.10.955933
MA0113.10.573327
MA0114.10.65856
MA0115.10.640975
MA0116.11.8412
MA0117.10.460927
MA0119.10.754603
MA0122.10.483183
MA0124.10.60338
MA0125.10.528543
MA0130.10
MA0131.10.23543
MA0132.10
MA0133.10
MA0135.12.01017
MA0136.10.164568
MA0139.11.12225
MA0140.10.135474
MA0141.10.461089
MA0142.10.275028
MA0143.10.197366
MA0144.10.362892
MA0145.10.343911
MA0146.10.00150604
MA0147.10.227226
MA0148.10.369009
MA0149.10.129939
MA0062.20.0994414
MA0035.20.135068
MA0039.20.000175116
MA0138.20.635695
MA0002.20.258808
MA0137.23.13129
MA0104.20.28434
MA0047.20.528161
MA0112.20.00190071
MA0065.20.231366
MA0150.10.24291
MA0151.10
MA0152.10.430874
MA0153.10.513757
MA0154.10.330254
MA0155.10.418917
MA0156.10.0444235
MA0157.11.30819
MA0158.10
MA0159.10.228288
MA0160.10.390619
MA0161.10
MA0162.13.64416e-05
MA0163.10.0345074
MA0164.10.205602
MA0080.20.147729
MA0018.20.187315
MA0099.20.139496
MA0079.21.51278e-06
MA0102.20.922526
MA0258.10.0645778
MA0259.10.241418
MA0442.10



ENCODE TF ChIP-seq peak enrichment analysis<b>Summary:</b> For each TF and each co-expression cluster, the number of promoters with ENCODE TF ChIP signal was compared with the rest of promoters from the robust set using Fisher's exact test. Clusters with significant ChIP enrichment (q <= 0.05) after Benjamini-Hochberg correction were retained. <br><b>Analyst:</b> Erik Arner<br><br>link to source dataset<br><br>data


No analysis results for this cluster

Relative expression of the co-expression cluster<b>Summary:</b>Co-expression clusters are compared against FANTOM5 samples to obtain relative expression. <br><b>Analyst:</b>NA<br><br>link to data source<br> data


This analysis result is provided for C0 - C305 clusters.